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https://www.readbyqxmd.com/read/29908522/management-of-complete-talocrural-luxations-by-selective-talocrural-arthrodesis-using-hybrid-transarticular-external-skeletal-fixation-in-dogs
#1
Cenk Yardımcı, Taylan Önyay, Kamil S İnal, Deniz B Özbakır, Ahmet Özak
OBJECTIVE:  This article presents a novel surgical technique in the management of open complete talocrural luxations and evaluates the results, and clinical benefits with its routine clinical utilization. STUDY DESIGN:  Retrospective study. ANIMALS:  Seventeen medium- or large-breed client-owned dogs of different breed, age and sex with complete talocrural luxations and radiographic follow-up of at least 24 weeks duration. METHOD:  Selective talocrural arthrodesis was performed by using a hybrid transarticular external skeletal fixator frame...
June 16, 2018: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/29908517/high-sensitive-cardiac-troponin-hs-tnt-levels-in-sudden-deaths-related-to-atherosclerotic-coronary-artery-disease
#2
Tim Beausire, Mohamed Faouzi, Cristian Palmiere, Tony Fracasso, Katarzyna Michaud
INTRODUCTION: Ischemic heart disease (IHD) related to atherosclerotic coronary artery disease (CAD) is one of the most prevalent causes of death in Europe. Postmortem evaluation of IHD remains a challenge because of possible non-specific autopsy finding in some autopsy cases, especially in early myocardial ischemia. High-sensitive cardiac troponin T (hs-TnT) is used today in clinical practice as the "gold standard" to diagnose the myocardial ischemia, and might also be applied as an ancillary tool for post-mortem evaluation...
June 4, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29908484/ethnic-differences-in-the-diagnosis-of-schizophrenia-and-mood-disorders-during-admission-to-an-academic-safety-net-psychiatric-hospital
#3
Jane E Hamilton, Angela M Heads, Thomas D Meyer, Pratikkumar V Desai, Olaoluwa O Okusaga, Raymond Y Cho
U.S. Hispanics, now the single largest minority group in the country, face unique mental health disparities. The current study utilizes Andersen's Behavioral Model of Health Service Use to examine ethnic disparities in receiving a schizophrenia or mood disorder diagnosis at psychiatric hospital admission. Our retrospective cohort study examined electronic health record data at an academic safety-net psychiatric hospital for adult patients (n = 5571) admitted between 2010 and 2013. Logistic regression with block-wise entry of predisposing, enabling and need variables was used to examine ethnic disparities in receiving a schizophrenia diagnosis at admission...
May 30, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29908433/a-retrospective-analysis-of-the-association-between-providing-nicotine-replacement-therapy-at-admission-and-motivation-to-quit-and-nicotine-withdrawal-symptoms-during-an-inpatient-psychiatric-hospitalization
#4
Chizimuzo T C Okoli, Yazan D Al-Mrayat, Charles I Shelton, Milan Khara
BACKGROUND: Psychiatric patients have high tobacco use prevalence, dependence, and withdrawal severity. A tobacco-free psychiatric hospitalization necessitates the management of nicotine withdrawal (NW) for tobacco using patients. NW management often requires the provision of approved nicotine replacement therapy (NRT) to patients, which may also motivate tobacco users towards cessation. However, few studies have examined the associations between providing NRT, motivation to quit, and NW among psychiatric patients...
June 7, 2018: Addictive Behaviors
https://www.readbyqxmd.com/read/29908418/the-fossil-study-flag-or-standard-7-3-induction-therapy-in-secondary-acute-myeloid-leukemia
#5
Vera Vulaj, Anthony J Perissinotti, James R Uebel, Victoria R Nachar, Gianni B Scappaticci, Ashley Crouch, Dale L Bixby, Patrick W Burke, Ivan Maillard, Moshe Talpaz, Bernard L Marini
Patients with secondary acute myeloid leukemia (sAML) have poor outcomes, with CR/CRi rates of 25-35% with standard 7 + 3 induction chemotherapy, while single center non-comparative analyses suggest promising outcomes with FLAG. We conducted a single-center, retrospective cohort study assessing outcomes in treatment-naïve patients with sAML treated with fludarabine, high-dose cytarabine, and granulocyte colony-stimulating factor (FLAG, n = 40) compared with 7 + 3 (n = 66). Median patient age was 63 years (range: 27-82) in the FLAG group and 60 years (range: 21-76) in the 7 + 3 group (P = 0...
June 1, 2018: Leukemia Research
https://www.readbyqxmd.com/read/29908410/beyond-the-walls-risk-factors-for-overdose-mortality-following-release-from-the-philadelphia-department-of-prisons
#6
Lia N Pizzicato, Rebecca Drake, Reed Domer-Shank, Caroline C Johnson, Kendra M Viner
BACKGROUND: High overdose mortality after release from state prison systems is well documented; however, little is known about overdose mortality following release from local criminal justice systems (CJS). The purpose of this study was to assess overdose mortality following release from a local CJS in Philadelphia, PA. METHODS: We conducted a retrospective cohort study of individuals released to the community from a local CJS between 2010 and 2016. Incarceration records were linked to overdose fatality data from the Medical Examiner's Office and death certificate records...
June 5, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29908405/objective-predictors-of-early-tolerance-to-ventral-intermediate-nucleus-of-thalamus-deep-brain-stimulation-in-essential-tremor-patients
#7
Shabbir Hussain Merchant, Sheng-Han Kuo, Yu Qiping, Linda Winfield, Guy McKhann, Sameer Sheth, Seth L Pullman, Blair Ford
OBJECTIVE: To identify pre-operative clinical and computerized spiral analysis characteristics that may help ascertain which patients with Essential Tremor (ET) will exhibit 'early tolerance' to ventral intermediate nucleus of thalamus (Vim) deep brain stimulation (DBS). METHODS: Identification of comparative characteristics of defined cases of 'early tolerance' versus patients with sustained satisfactory response treated with Vim DBS surgery for medically-refractory ET, based on retrospective chart review by a clinician blinded to the findings of computerized spiral analysis...
June 5, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29908382/open-versus-french-door-laminoplasty-for-the-treatment-of-cervical-multilevel-compressive-myelopathy-a-meta-analysis
#8
REVIEW
Wenqi Luo, Yueying Li, Jianhui Zhao, Rui Gu, Rui Jiang, Phd Feng Lin
PURPOSE: To compare the clinical outcomes and postoperative complications between open-door laminoplasty (ODL) versus French-door laminoplasty (FDL) for the treatment of cervical multilevel compressive myelopathy. METHODS: We comprehensively searched PubMed, EMBASE, Cochrane library, and China National Knowledge Infrastructure (CNKI) to identify relevant articles. The search results were last updated on January 1, 2018. All values of weighted mean difference (WMD) and odds ratio(OR) are expressed as ODL relative to FDL...
June 13, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29908376/the-increased-level-of-tspan5-in-villi-suggests-more-proliferation-and-invasiveness-of-trophoblasts-in-tubal-pregnancy
#9
Tianyang Gao, Yingqiu Liang, Haiyu Tang, Li Quan
OBJECTIVE: This study was to determinate the expression of Tspan5 in tubal ectopic implantation sites and to explore the correlation of the expressive level of Tspan5 at maternal-fetal interface and the occurrence of tubal ectopic pregnancy. STUDY DESIGN: This is a retrospective study. Trophoblastic and endometrial tissues were collected from tubal ectopic pregnancy(Total of 40), and intrauterine pregnancy(Total of 41), who had voluntary abortion, non-pregnancy women(Total of 12), who recieved an diagnostic uterine curettage before IVF-ET for male infertility...
June 5, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29908371/the-addition-of-minute-ventilation-to-rate-responsive-pacing-improves-heart-rate-score-more-than-accelerometer-alone
#10
Mark Richards, Brian Olshansky, Arjun D Sharma, Nicholas Wold, Paul Jones, David Perschbacher, Bruce L Wilkoff
BACKGROUND: Heart Rate Score (HRSc)≥70%, a novel parameter, predicts risk of mortality in patients with implantable defibrillators and identifies patients who have survival benefit with DDDR versus DDD pacing. OBJECTIVE: DDDR pacing lowers HRSc and dual-sensor with minute ventilation (MV) and accelerometer (XL) improves HRSc more than accelerometer (XL) alone in patients requiring pacemakers (PM). METHODS: HRSc, the percent of all beats in the predominant 10 bpm bin, was calculated...
June 13, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29908357/coronal-trunk-imbalance-in-idiopathic-scoliosis-does-gravity-line-localisation-confirm-the-physical-findings
#11
Thibault Hernandez, Thomas Thenard, Claudio Vergari, Leopold Robichon, Wafa Skalli, Raphaël Vialle
BACKGROUND: Adolescent idiopathic scoliosis (AIS) can require surgical procedures that have major consequences. Coronal imbalance as assessed clinically using a plumb line is a key criterion for selecting patients to surgery. Nevertheless, the reference standard for assessing postural balance of the trunk is gravity line localisation within a validated frame of reference. Recent studies have established that the gravity line can be localised after body contour reconstruction from biplanar radiographs...
June 13, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29908356/total-hip-arthroplasty-after-failed-fixation-of-a-proximal-femur-fracture-analysis-of-59-cases-of-intra-and-extra-capsular-fractures
#12
Antoine Morice, Florian Ducellier, Pascal Bizot
INTRODUCTION: The indications for total hip arthroplasty (THA) after failed internal fixation of a proximal femur fracture vary. Published studies on this topic are broad-ranging and do not distinguish between intracapsular and extracapsular fractures. This led us to conduct a retrospective analysis comparing the clinical outcomes, radiological outcomes, technical problems and complications between these two types of fractures. HYPOTHESIS: The functional outcomes of THA after an extracapsular fracture will be worse than the ones after an intracapsular fracture...
June 13, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29908355/medial-acetabular-wall-breach-in-total-hip-arthroplasty-is-full-weight-bearing-possible
#13
Filippo Mandelli, Simon Tiziani, Jürgen Schmitt, Clément M L Werner, Hans-Peter Simmen, Georg Osterhoff
BACKGROUND: A breach of the medial acetabular wall is a phenomenon seen frequently due to over-reaming during total hip arthroplasty (THA). The consequences of this issue are not fully understood particularly in cementless THA. A retrospective study was performed to answer whether: 1) immediate postoperative full-weight bearing in the presence of a medial acetabular wall breach after THA results in more short-term revisions of the acetabular component, 2) increases the risk for migration of the acetabular component? HYPOTHESIS: Immediate full-weight bearing in the presence of a medial breach is not associated with an increased likelihood for acetabular-related revision surgery or migration of the cup...
June 13, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29908338/surgical-and-oncologic-outcomes-of-radical-abdominal-trachelectomy-versus-hysterectomy-for-stage-ia2-ib1-cervical-cancer
#14
Jing Guo, Ying Zhang, Xiaofei Chen, Lin Sun, Kai Chen, Xiugui Sheng
STUDY OBJECTIVE: To compare the surgical and oncologic outcomes between radical abdominal trachelectomy and radical hysterectomy (RH) for stage IA2-IB1 cervical cancer. DESIGN: Ⅱ-2: : Retrospective cohort study. SETTING: Shandong Cancer Hospital. PATIENTS: 329 patients with IA2-IB1 cervical cancer. INTERVENTIONS: All patients underwent radical abdominal trachelectomy (ART) or RH. MEASUREMENTS AND MAIN RESULTS: All patients were divided into ART (n=143) and RH (n=186) group according to surgical approach...
June 13, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29908329/the-incidence-of-vocal-fold-motion-impairment-after-primary-thyroid-and-parathyroid-surgery-for-a-single-high-volume-academic-surgeon-determined-by-pre-and-immediate-post-operative-fiberoptic-laryngoscopy
#15
Vaninder K Dhillon, Eleni Rettig, Salem I Noureldine, Dane J Genther, Ahmed Hassoon, Mai G Al Khadem, Ozan B Ozgursoy, Ralph P Tufano, Charles W Cummings
BACKGROUND: Vocal fold motion impairment (VFMI) is a well-recognized complication of thyroid and parathyroid surgery. Preoperative counseling requires a thorough understanding of the incidence, risk factors, and value of early diagnosis of postoperative VFMI. Our objective is to describe the incidence of and risk factors for VFMI for a single high-volume academic surgeon, and to assess the utility of immediate postoperative fiberoptic laryngoscopy (FOL) in early diagnosis of VFMI. METHODS: Retrospective cohort study of patients undergoing primary thyroid and parathyroid procedures by a single high-volume surgeon at an academic tertiary care center...
June 13, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29908230/additional-cytogenetic-abnormalities-with-philadelphia-chromosome-positive-acute-lymphoblastic-leukemia-on-allogeneic-stem-cell-transplantation-in-the-tyrosine-kinase-inhibitor-era
#16
Yu Akahoshi, Shuichi Mizuta, Hiroaki Shimizu, Naoyuki Uchida, Takahiro Fukuda, Heiwa Kanamori, Makoto Onizuka, Yukiyasu Ozawa, Kazuteru Ohashi, Shuichi Ohta, Tetsuya Eto, Junji Tanaka, Yoshiko Atsuta, Shinichi Kako
Cytogenetic abnormalities are well-known and powerful independent prognostic factor for various hematological disorders. Although the combination of chemotherapy with tyrosine kinase inhibitor (TKI) is now considered the standard of care in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia, little is known about the impact of additional cytogenetic abnormalities (ACAs). Therefore, we retrospectively evaluated 1375 adult patients who underwent their first allogeneic hematopoietic stem cell transplantation in the TKI era...
June 13, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29908227/hypogastric-preservation-using-retrograde-endovascular-bypass
#17
Mathew Wooster, Paul Armstrong, Martin Back
OBJECTIVE: Maintenance of pelvic circulation has been connected to reduced risks of ischemic colitis, buttock claudication, erectile dysfunction, and spinal cord ischemia during the treatment of extensive aorto-iliac aneurysmal disease. We evaluate the mid to late follow up of a cohort of patients treated using one preservation technique, the endovascular external (EIA) to internal (IIA) iliac artery bypass. METHODS: All patients undergoing elective retrograde EIA-IIA endovascular bypass at a single institution were retrospectively reviewed over a ten-year period from 2006-2016...
June 13, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29908195/safety-of-next-day-discharge-following-lobectomy-have-we-broken-the-speed-limit
#18
Stephen Greer, Ashley D Miller, Jeremiah S Smith, Jenny M Holcombe, James R Headrick
BACKGROUND: Utilizing our standardized approach to air leak reduction (STAR) protocol has led to a continual decrease in the need for inpatient recovery following lobectomy. Although next day discharges do occur, the current literature hasn't addressed their safety. We analyzed our STAR dataset to study this group and their outcomes. METHODS: A retrospective review of prospectively collected data from the STAR dataset was performed. Characteristics were compared between patients discharged on postoperative day (POD) 1 and those with longer admissions...
June 13, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29908155/pharmacokinetics-of-continuous-infusion-beta-lactams-in-the-treatment-of-acute-pulmonary-exacerbations-in-adult-cystic-fibrosis-patients
#19
Lisa T Hong, Theodore G Liou, Rishi Deka, Jordan B King, Vanessa Stevens, David C Young
BACKGROUND: Several clinical trials have demonstrated the efficacy of continuous infusion (CI) beta-lactam (BL) antibiotics in cystic fibrosis (CF) patients; however, little is known regarding pharmacokinetic changes during treatment of an acute pulmonary exacerbation (APE). Identifying and understanding these changes may assist in optimizing antibiotic dosing during APE treatment. METHODS: This study is a retrospective cohort study of 162 adult CF patients admitted to the University of Utah Hospital between January 1, 2008 and May 15, 2014 for treatment of an APE with both a CI BL and intravenous tobramycin...
June 13, 2018: Chest
https://www.readbyqxmd.com/read/29908131/low-body-mass-index-is-a-risk-factor-for-hyperkalaemia-associated-with-angiotensin-converting-enzyme-inhibitors-and-angiotensin-ii-receptor-blockers-treatments
#20
T Hirai, R Yamaga, A Fujita, T Itoh
WHAT IS KNOWN AND OBJECTIVE: Angiotensin converting enzyme inhibitors (ACEI) and angiotensin II receptor blockers (ARB) represent the cornerstones of hypertension and congestive heart failure treatment. Risk factors for hyperkalaemia associated with ACEI and ARB are chronic kidney disease and concomitant medications which increase serum potassium level. Body mass index (BMI) also affects pharmacokinetics of ACEI and ARB and potassium disposition. We evaluated the relationship between BMI and hyperkalaemia associated with ACEI and ARB treatments...
June 16, 2018: Journal of Clinical Pharmacy and Therapeutics
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