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https://www.readbyqxmd.com/read/29775738/humoral-and-mucosal-immune-responses-in-meagre-argyrosomus-regius-juveniles-fed-diets-with-varying-inclusion-levels-of-carob-seed-germ-meal
#1
Francisco Antonio Guardiola, Carolina Barroso, Paula Enes, Ana Couto, Patricia Díaz-Rosales, António Afonso, Erika Kanashiro, Helena Peres, Elisabete Matos, Aires Oliva-Teles, Pedro Pousão-Ferreira, Benjamín Costas
Many studies have assessed the effects of incorporation of plant feedstuffs in fish diets on growth performance, whereas few studies have addressed the effects of fish meal replacement by plant protein sources on fish immune parameters. Thus, the aim of this study was to evaluate the effects on immune response of different inclusion levels of carob seed germ meal (CSGM) as partial replacement for fish meal in diets for meagre (Argyrosomus regius) juveniles. Fish were fed four experimental diets with increased CSGM inclusion levels [0% (control), 7...
May 15, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29772836/soybean-hop-alleviates-estrogen-deficiency-related-bone-loss-and-metabolic-dysfunction-in-ovariectomized-rats-fed-a-high-fat-diet
#2
Dasom Noh, Yeni Lim, Hansol Lee, Hyejin Kim, Oran Kwon
Soybeans and hops have been traditionally used as a natural estrogen replacement therapy and their major active ingredients, isoflavones and prenylflavanones, are known to have estrogenic/antiestrogenic effects depending on the target organ. However, their potential benefits are still subject to controversies. The present study investigated the dual effect of soy isoflavones plus hop prenylflavanones (Soy-Hop) on bone loss and metabolic dysfunction under estrogen deficient condition. Rats were sham-operated ( n = 10) or ovariectomized (OVX; n = 40) and then fed a high-fat diet (HFD) to develop hyperlipidemia in OVX rats within the experimental period of 8 weeks...
May 17, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29763365/effect-of-cross-linked-chitosan-iron-iii-on-vascular-calcification-in-uremic-rats
#3
Barbara Bruna Abreu de Castro, Wander Barros do Carmo, Paulo Giovani de Albuquerque Suassuna, Moises Carminatti, Julia Bianchi Brito, Wagner Vasques Dominguez, Ivone Braga de Oliveira, Vanda Jorgetti, Melani Ribeiro Custodio, Helady Sanders-Pinheiro
Cross-linked chitosan iron (III) is a chitin-derived polymer with a chelating effect on phosphorus, but it is untested in vascular calcification. We evaluated this compound's ability to reduce hyperphosphatemia and its effect on vascular calcification in uremic rats using an adenine-based, phosphorus-rich diet for seven weeks. We used a control group to characterize the uremia. Uremic rats were divided according the treatment into chronic kidney disease, CKD-Ch-Fe(III)CL (CKD-Ch), CKD-calcium carbonate, or CKD-sevelamer groups...
May 2018: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29756964/a%C3%A3-ai-improves-non-alcoholic-fatty-liver-disease-nafld-induced-by-fructose
#4
Mayara Medeiros de Freitas Carvalho, Larissa Lélis Teixeira Reis, Juliana Márcia Macedo Lopes, Nara Nunes Lage, Joyce Ferreira da Costa Guerra, Helena Porto Zago, Larissa De Freitas Bonomo, Renata Rebeca Pereira, Wanderson Geraldo de Lima, Marcelo Eustáquio Silva, Maria Lucia Pedrosa
INTRODUCTION: the excessive consumption of fructose can cause liver damage, characteristic of non-alcoholic fatty liver disease (NAFLD) associated with changes in lipid metabolism and antioxidant defenses. Açai, the fruit of Euterpe oleraceaMart., has demonstrated numerous biological activities, including anti-inflammatory, antioxidant, and lipid metabolism modulating action. OBJECTIVE: we evaluated the benefits of açai supplementation on liver damage caused by replacing starch with fructose in rats...
February 16, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29746171/increased-task-channel-mediated-currents-underlie-high-fat-diet-induced-vagal-afferent-dysfunction
#5
Sung Jin Park, Yang Yu, Brittany Wagner, William C Valinsky, Alan E Lomax, Michael J Beyak
We have previously demonstrated that satiety sensing vagal afferent neurons are less responsive to meal-related stimuli in obesity, due to reduced electrical excitability. As leak K+ currents are key determinants of membrane excitability, we hypothesized that leak K+ currents are increased in vagal afferents during obesity. Diet-induced obesity (DIO) was induced by feeding C57Bl/6J mice a high fat fed diet (60% energy from fat - HFF) for 8-10 weeks. In vitro extracellular recordings were performed on jejunal afferent nerves...
May 10, 2018: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/29743860/ameliorative-effects-of-spirulina-platensis-against-lead-induced-nephrotoxicity-in-newborn-rats-modulation-of-oxidative-stress-and-histopathological-changes
#6
Manel Gargouri, Ahlem Soussi, Amel Akrouti, Christian Magné, Abdelfattah El Feki
Our experimental work was aimed at evaluating the safety and protective effects of dietary spirulina supplementation on the kidney of newborn rats, the offspring of lead contaminated lactating mothers. Female rats were randomly divided into four groups: group I (control) was given a normal diet, group II (positive control, S) received a diet enriched with spirulina , group III received only lead through drinking water (Pb), and group IV received both a diet enriched with spirulina and lead contaminated water (S Pb)...
2018: EXCLI journal
https://www.readbyqxmd.com/read/29742924/inhibition-of-aortic-calcification-by-policosanol-in-dyslipidemic-rabbits-is-enhanced-by-pentoxifylline-potential-role-of-pcsk9
#7
Mohamed M Elseweidy, Hoda E Mohamed, Rania A Elrashidy, Hebatallah H Atteia, Gehad M Elnagar
Policosanol (POL) is a hypocholesterolemic drug of natural origin and has been shown to reduce circulating levels of proprotein convertase subtilisin/kexin type 9 (PCSK9) in healthy participants. Recently, we have reported that POL can attenuate aortic calcification in diabetic dyslipidemic rats; however, the underlying mechanism is not fully elucidated. We aimed to investigate the effect of POL on aortic calcification and whether PCSK9 has a contributory role and also to examine whether the combination of POL with pentoxifylline (PTX) as anti-tumor necrosis factor α would offer additional benefits...
January 1, 2018: Journal of Cardiovascular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29738375/magnesium-citrate-protects-against-vascular-calcification-in-an-adenine-induced-crf-rat-model
#8
PhD Zhihui-Yao, M D Yang-Xu, M D Weidong-Ma, Xin-Yuan Sun, PhD Shan-Jia, M D Yang-Zheng, M D Xiaohuan-Liu, M D Yajie-Fan, M D Congxia-Wang
BACKGROUND: Hypomagnemia was identified as a strong risk factor for cardiovascular disease in patients with chronic renal failure (CRF). However, the effects of magnesium (Mg) on vascular calcification (VC) have not been fully elucidated. Thus we aim to determine the effects of Mg citrate (MgCit) on VC in CRF rats. METHODS: Rats were divided into 5 groups: group 1 (normal diet); group 2 (normal diet with MgCit); group 3 (VC model of CRF induced by 0.75% adenine and 0...
April 24, 2018: Journal of Cardiovascular Pharmacology
https://www.readbyqxmd.com/read/29735797/modulatory-effect-of-dietary-inclusion-of-aegle-marmelos-fruits-against-cisplatin-induced-hepatotoxicity-in-wistar-rats
#9
Saket S Chandel, Mrunal Shirsat, Ram K Sahu, Siva S Nayak
INTRODUCTION AND AIM: Aegle marmelos is an important traditional herbal medicine used in India. The dietary inclusion of the plant has never exposed earlier for its hepatoprotective activity. This study aimed to investigate the modulator efficacy of dietary inclusion of Aegle marmelos against Cisplatin - induced hepatotoxicity in Wistar albino rats. MATERIAL AND METHODS: Animals were divided into five different groups; Group I was given basal diets only, Group II was fed basal diets with Aegle marmelos in 4% concentration, while Group III was fed basal diets co-administered with Cisplatin...
April 9, 2018: Annals of Hepatology
https://www.readbyqxmd.com/read/29722847/dietary-acid-load-and-bone-turnover-during-long-duration-spaceflight-and-bed-rest
#10
Sara R Zwart, Barbara L Rice, Holly Dlouhy, Linda C Shackelford, Martina Heer, Matthew D Koslovsky, Scott M Smith
Background: Bed rest studies document that a lower dietary acid load is associated with lower bone resorption. Objective: We tested the effect of dietary acid load on bone metabolism during spaceflight. Design: Controlled 4-d diets with a high or low animal protein-to-potassium (APro:K) ratio (High and Low diets, respectively) were given to 17 astronauts before and during spaceflight. Each astronaut had 1 High and 1 Low diet session before flight and 2 High and 2 Low sessions during flight, in addition to a 4-d session around flight day 30 (FD30), when crew members were to consume their typical in-flight intake...
May 1, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29704554/growth-physiological-antioxidants-and-immune-response-of-african-catfish-clarias-gariepinus-b-to-dietary-clove-basil-ocimum-gratissimum-leaf-extract-and-its-susceptibility-to-listeria-monocytogenes-infection
#11
Mohsen Abdel-Tawwab, Ibrahim Adeshina, Adetola Jenyo-Oni, Emmanual K Ajani, Benjami O Emikpe
Clove basil, Ocimum gratissimum, is a native plant to Africa and grows virtually in tropical and subtropical regions. It has good aroma and its leaves have become used as a spicy and in traditional medicine. The use of plant leaves in fish diets may deteriorate their growth because it may content anti-nutritional factors0 Thus, it is better to use plants leaves extract. In the current study, clove basil leaves extract (CBLE) was administrated to African catfish, Clarias gariepinus (B.) for 12 weeks to evaluate its effect on growth performance, physiological, antioxidants, and innate immunity variables...
April 25, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29702236/probiotic-potential-of-bacillus-velezensis-jw-antimicrobial-activity-against-fish-pathogenic-bacteria-and-immune-enhancement-effects-on-carassius-auratus
#12
Yanglei Yi, Zhenhua Zhang, Fan Zhao, Huan Liu, Lijun Yu, Jiwei Zha, Gaoxue Wang
This study evaluated the probiotic potential of B. velezensis JW through experimental and genomic analysis approaches. Strain JW showed antimicrobial activity against a broad range of fish pathogenic bacteria including Aeromonas hydrophila, Aeromonas salmonicida, Lactococcus garvieae, Streptococcus agalactiae, and Vibrio Parahemolyticus. Fish (Carassius auratus) were fed with the diets containing 0 (control), 107 , and 109  cfu/g of B. velezensis JW for 4 weeks. Various immune parameters were examined at 1, 2, 3, and 4 weeks of post-feeding...
April 24, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29698527/effect-of-phenolic-extracts-from-different-extra-virgin-olive-oil-varieties-on-osteoblast-like-cells
#13
Lucía Melguizo-Rodríguez, Javier Ramos-Torrecillas, Francisco Javier Manzano-Moreno, Rebeca Illescas-Montes, Ana Rivas, Concepción Ruiz, Elvira De Luna-Bertos, Olga García-Martínez
The reported incidence of osteoporosis is lower in countries in which the Mediterranean diet predominates, and this apparent relationship may be mediated by the phenolic compounds present in olive oil. The objective of this study was to determine the effect of phenolic extracts from different varieties of extra-virgin olive oil (Picual, Arbequina, Picudo, and Hojiblanca) on the differentiation, antigenic expression, and phagocytic capacity of osteoblast-like MG-63 cells. At 24 h of treatment a significant increase in phosphatase alkaline activity and significant reductions in CD54, CD80, and HLA-DR expression and in phagocytic activity were observed in comparison to untreated controls...
2018: PloS One
https://www.readbyqxmd.com/read/29694831/atorvastatin-in-nano-particulate-formulation-abates-muscle-and-liver-affliction-when-coalesced-with-coenzyme-q10-and-or-vitamin-e-in-hyperlipidemic-rats
#14
S M Farrag, M A Hamzawy, M F El-Yamany, M A Saad, N N Nassar
AIMS: Statins are the most widely used to lower elevated low-density lipoprotein levels and preventing cardiovascular diseases in humans. However, about 20% of patients treated with this medication suffer from statin-related myalgia. To this end, this study investigated the potential effect of nano-particulate formulation in alleviating the muscles and liver damage either alone or when co-administered with nano coenzyme Q10 and nano vitamin E. MATERIALS AND METHODS: Male Wistar rats were fed normal diet or high-fat diet for 12 weeks, following which rats were treated with either (i) atorvastatin (5 or 20 mg/kg/day, p...
April 22, 2018: Life Sciences
https://www.readbyqxmd.com/read/29694393/replacement-of-fish-oil-with-palm-oil-effects-on-growth-performance-innate-immune-response-antioxidant-capacity-and-disease-resistance-in-nile-tilapia-oreochromis-niloticus
#15
Christian Larbi Ayisi, Jinliang Zhao, Jun-Wei Wu
This study was conducted to investigate the effects of replacing dietary fish oil (FO) with palm oil (PO) in juvenile Nile tilapia, Oreochromis niloticus (9.34± 0.02g initial weight) with emphasis on growth performance, digestive enzyme activities as well as serum biochemical parameters. Also, lysozyme activity (LYZ), respiratory burst (RB), superoxide dismutase (SOD), catalase (CAT) and resistance to Streptococcus iniae were investigated. Fish were stocked in 15 rectangular fiber glass tanks (150× 60× 40 cm) at 40 fish per tank with water maintained at 210 litres...
2018: PloS One
https://www.readbyqxmd.com/read/29690515/acid-balance-dietary-acid-load-and-bone-effects-a-controversial-subject
#16
REVIEW
Lynda Frassetto, Tanushree Banerjee, Neil Powe, Anthony Sebastian
Modern Western diets, with higher contents of animal compared to fruits and vegetable products, have a greater content of acid precursors vs. base precursors, which results in a net acid load to the body. To prevent inexorable accumulation of acid in the body and progressively increasing degrees of metabolic acidosis, the body has multiple systems to buffer and titrate acid, including bone which contains large quantities of alkaline salts of calcium. Both in vitro and in vivo studies in animals and humans suggest that bone base helps neutralize part of the dietary net acid load...
April 21, 2018: Nutrients
https://www.readbyqxmd.com/read/29684610/fishmeal-replacement-by-rice-protein-concentrate-with-xylooligosaccharides-supplement-benefits-the-growth-performance-antioxidant-capability-and-immune-responses-against-aeromonas-hydrophila-in-blunt-snout-bream-megalobrama-amblycephala
#17
Kenneth Prudence Abasubong, Wen-Bin Liu, Ding-Dong Zhang, Xiang-Yang Yuan, Si-Lei Xia, Chao Xu, Xiang-Fei Li
This study aimed to investigate the effects of fishmeal (FM) replacement by rice protein concentrate (RPC) with a xylooligosaccharides supplement on the growth performance, antioxidant capability and immune response against Aeromonas hydrophila in blunt snout bream (Megalobrama amblycephala). Fish (46.85 ± 0.34 g) were randomly assigned to one of 6 diets, namely the control diet (containing FM), the RPC diet (FM replaced by RPC) and RPC diet supplemented with 0.5, 1.5, 2.3 and 3% XOS respectively, for 8 weeks...
April 20, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29684600/effect-of-high-dietary-starch-levels-on-growth-hepatic-glucose-metabolism-oxidative-status-and-immune-response-of-juvenile-largemouth-bass-micropterus-salmoides
#18
Shi-Mei Lin, Chao-Ming Shi, Ming-Ming Mu, Yong-Jun Chen, Li Luo
An experimental trial was conducted to investigate the effects of high dietary starch levels on growth, hepatic glucose metabolism enzyme, antioxidant capacity and immune responses of largemouth bass, Micropterus salmoides. Fish (initial body weight: 16.9 ± 0.24 g) were fed three isonitrogenous and isoenergetic semi-purified diets containing 5%, 10% and 20% wheat starch, respectively. The results indicated that fish fed 5% and 10% starch diets showed significantly better weight gain, specific growth rate (SGR), protein efficiency ratio (PER) and feed conversion ratio (FCR) compared with that fed 20% starch diet...
April 20, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29674134/higher-dietary-acid-load-is-associated-with-higher-likelihood-of-peripheral-arterial-disease-among-american-adults
#19
Mohsen Mazidi, Dimitri P Mikhailidis, Maciej Banach
OBJECTIVE: To explore the association between dietary acid load, potential renal acid load (PRAL) and net endogenous acid production (NEAP), and peripheral arterial disease (PAD) in a national representative sample of American adults. METHODS: The National Health and Nutrition Examination Survey (NHANES) database (for 1999-2002) was used. PAD was diagnosed by ankle brachial index assessment. Analysis of covariance was used to examine adjusted mean of different dietary acid load by PAD status; multivariable logistic regression was used to relate dietary acid load with prevalent PAD...
March 9, 2018: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/29673542/maternal-nutritional-supplementation-with-fish-oil-and-or-leucine-improves-hepatic-function-and-antioxidant-defenses-and-minimizes-cachexia-indexes-in-walker-256-tumor-bearing-rats-offspring
#20
Natália Angelo da Silva Miyaguti, Sarah Christine Pereira de Oliveira, Maria Cristina Cintra Gomes-Marcondes
In this study, we hypothesized that throughout the pregnancy/weaning period, nutritional supplementation with leucine (which improves protein synthesis) and/or fish oil (rich in omega-3, which modulates oxidative stress) can minimize/improve cachexia-induced damage in rat offspring. Thus, we investigated the maternal supplementation with these nutrients over the modulation of cachexia index and liver function in tumor-bearing rats offspring. Pregnant rats were fed control, leucine, omega-3, and leucine/omega-3 diets, which were given throughout the gestational and weaning periods...
March 2018: Nutrition Research
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