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https://www.readbyqxmd.com/read/28729815/symposium-report-an-evidence-based-approach-to-ibs-and-cic-applying-new-advances-to-daily-practice-a-review-of-an-adjunct-clinical-symposium-of-the-american-college-of-gastroenterology-meeting-october-16-2016-%C3%A2-las-vegas-nevada
#1
William D Chey
Many nonpharmacologic and pharmacologic therapies are available to manage irritable bowel syndrome (IBS) and chronic idiopathic constipation (CIC). The American College of Gastroenterology (ACG) regularly publishes reviews on IBS and CIC therapies. The most recent of these reviews was published by the ACG Task Force on the Management of Functional Bowel Disorders in 2014. The key objective of this review was to evaluate the efficacy of therapies for IBS or CIC compared with placebo or no treatment in randomized controlled trials...
February 2017: Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28728991/analysis-of-factors-associated-with-patient-or-caretaker-regret-following-surgery-for-fecal-incontinence
#2
Bhalaajee Meenakshi-Sundaram, Caitlin T Coco, James R Furr, Byron P Dubow, Christopher E Aston, Jennifer Lewis, Gennady Slobodov, Bradley P Kropp, Dominic C Frimberger
PURPOSE: The Malone Antegrade Continence Enema (MACE) has been a successful and widely used procedure to achieve fecal continence in children. We present data on the previously uninvestigated issue of patient and caretaker regret following surgery for intractable constipation and fecal incontinence. MATERIALS AND METHODS: We reviewed all patients undergoing antegrade continence enema or cecostomy creation at a single institution between 2006 and 2016. Patients and caretakers were assessed for decisional regret utilizing the Decisional Regret Scale...
July 17, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28728707/complex-pediatric-constipation-a-case-study-of-a-child-with-a-malone-appendicostomy
#3
Lisa C Witte, Michelle Tate
No abstract text is available yet for this article.
July 17, 2017: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/28728515/the-prevalence-of-constipation-at-admission-and-after-one-week-of-palliative-care-a-multicenter-study
#4
Sebastiano Mercadante, Francesco Masedu, Marco Maltoni, Daniela De Giovanni, Luigi Montanari, Cristina Pittureri, Raffaella Bertè, Laura Ursini, Franco Marinangeli, Federica Aielli
AIM: To assess the prevalence and intensity of constipation in advanced-cancer patients referred to palliative care, and to assess changes after one week of specialist palliative care. METHODS: Prospective multicenter study in advanced patients for a period of one year. At admission (T0), age, gender, primary tumor, concomitant diseases, Karnofsky status, Palliative prognostic score (PaP) Edmonton Symptom Assessment scale (ESAS), MDAS (Memorial Delirium Assessment Scale), and bowel function index (BFI) were collected...
July 20, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28728315/defecographic-findings-in-patients-with-severe-idiopathic-chronic-constipation
#5
Rahmatollah Rafiei, Azadeh Bayat, Masoud Taheri, Zahra Torabi, Lotfollah Fooladi, Saideh Husaini
Background/Aims: Chronic constipation is a common gastrointestinal disorder diagnosed using Rome III criteria. Defecography is a radiographic method used to identify anatomic abnormalities of anorectum. The present study aimed to evaluate the defecographic findings in patients with severe idiopathic chronic constipation. Methods: One hundred patients, who complained of severe idiopathic chronic constipation with abnormal balloon expulsion test, underwent defecography after injection of barium...
July 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/28727377/laparoscopic-pectopexy-initial-experience-of-single-center-with-a-new-technique-for-apical-prolapse-surgery
#6
Ahmet Kale, Alper Biler, Hasan Terzi, Taner Usta, Ebru Kale
OBJECTIVE: To share our first experience with laparoscopic pectopexy, a new technique for apical prolapse surgery, and to evaluate the feasibility of this technique. MATERIALS AND METHODS: Seven patients with apical prolapse underwent surgery with laparoscopic pectopexy. The lateral parts of the iliopectineal ligament were used for a bilateral mesh fixation of the descended structures. The medical records of the patients were reviewed, and the short-term clinical outcomes were analyzed...
June 14, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28724419/real-life-clinical-practice-results-with-vinflunine-in-patients-with-relapsed-platinum-treated-metastatic-urothelial-carcinoma-an-italian-multicenter-study-movie-goirc-01-2014
#7
Rodolfo Passalacqua, Silvia Lazzarelli, Maddalena Donini, Rodolfo Montironi, Rosa Tambaro, Ugo De Giorgi, Sandro Pignata, Raffaella Palumbo, Giovanni Luca Ceresoli, Gianluca Del Conte, Giuseppe Tonini, Franco Morelli, Franco Nolè, Stefano Panni, Ermanno Rondini, Annalisa Guida, Paolo Andrea Zucali, Laura Doni, Elisa Iezzi, Caterina Caminiti
BACKGROUND: Vinflunine is the only chemotherapeutic agent shown to improve survival in platinum-refractory patients with metastatic transitional cell carcinoma of the urothelium (TCCU) in a phase III clinical trial, which led to product registration for this indication in Europe. The aim of this study was to assess the efficacy of vinflunine and to evaluate the prognostic significance of risk factors in a large, unselected cohort of patients with metastatic TCCU treated according to routine clinical practice...
July 19, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28722093/-a-multicenter-randomized-controlled-trial-of-wheat-cellulose-particles-in-the-treatment-of-internal-hemorrhoids
#8
Yunhua Peng, Wei Yang, Yehuang Wang, Xiaohua Fan, Xueping Zheng, Juanjuan Gai
OBJECTIVE: To evaluate the efficacy and safety of wheat cellulose particles (testa triticum tricum purify, Fiberform) in the treatment of internal hemorrhoid. METHODS: A multicenter randomized controlled clinical trial was adopted. From October 2015 to July 2016, 60 patients with internal hemorrhoid were enrolled from three medical centers, including Department of Anorectum, Shuguang Hospital of Shanghai University of Traditional Chinese Medicine, Department of Anorectum, The Third Affiliated Hospital of Nanjing University of Chinese Medicine, Department of Anorectum, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine...
July 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28717406/neurogenic-bowel-dysfunction-in-patients-with-neurogenic-bladder
#9
Laura Martinez, Leila Neshatian, Rose Khavari
Patients with primary neurologic conditions often experience urinary and bowel dysfunction due to loss of sensory and/or motor control. Neurogenic bowel dysfunction is frequently characterized by both constipation and fecal incontinence. In general, the management of neurogenic bowel dysfunction has been less well studied than bladder dysfunction despite their close association.. It is widely accepted that establishment of a multifaceted bowel regimen is the cornerstone of conservative management. Continuing assessment is necessary to determine need for more invasive interventions...
December 2016: Current Bladder Dysfunction Reports
https://www.readbyqxmd.com/read/28716693/the-effects-of-reflexology-on-constipation-and-motor-functions-in-children-with-cerebral-palsy
#10
Bulent Elbasan, Sabiha Bezgin
BACKGROUND: There is no evidence regarding the effects of reflexology on constipation and motor functions in children with cerebral palsy. This study was planned to investigate the effects of reflexology combined with neurodevelopmental therapy on constipation and motor functions in children with cerebral palsy. METHODS: Forty children between the ages of 3 and 15 years with cerebral palsy within levels 3/4/5 according to the Gross Motor Function Classification System (GMFCS) were included in the study...
June 29, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/28714426/suicide-following-acute-admissions-for-physical-illnesses-across-england-and-wales
#11
S E Roberts, A John, U Kandalama, J G Williams, R A Lyons, K Lloyd
BACKGROUND: The study aim was to establish and quantify suicide risk following acute admissions for all major physical illnesses, for confirmatory purposes, from two independent information sources from different countries. METHODS: Record linkage of inpatient and death certificate data for 11 004 389 acute admissions for physical illnesses in England and 713 496 in Wales. The main outcome measure was standardised mortality ratios (SMRs) for suicide at 1 year following discharge from hospital...
July 17, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28713271/luminally-acting-agents-for-constipation-treatment-a-review-based-on-literatures-and-patents
#12
REVIEW
Hong Yang, Tonghui Ma
Constipation is one of the most frequently reported gastrointestinal (GI) disorders that negatively impacts quality of life and is associated with a significant economic burden to the patients and society. Traditional treatments including lifestyle modification and laxatives are often ineffective in the more severe forms of constipation and over the long term. New medications targeting at intestinal chloride channels and colonic serotonin receptors have been demonstrated effective in recent years. Emerging agents focusing on improving intestinal secretion and/or colonic motility have been shown effective in animal models and even in clinical trials...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28712887/prostatic-ductal-adenocarcinoma-a-rare-entity-with-radiological-dilemma-demanding-endoscopic-biopsy
#13
S S Yadav, Pushpendra Baghel, Vinay Tomar, Neeraj Agarwal, Devendra Dhakad
This is a rare case of prostatic ductal adenocarcinoma( PDA). A 75 year old gentleman presented with complaints of lower urinary tract symptoms(LUTS), constipation and occasional heamaturia. The clinical and radiological differentiation from other retroperitoneal soft cystic lesion was difficult and FNAC from papillary solid components of cyst was required to reach diagnosis. TRUS guided biopsy was performed in view of raised serum PSA (> 100ng/ml), But, the cyst got ruptured without yielding any tissue for biopsy...
July 13, 2017: Urology
https://www.readbyqxmd.com/read/28712737/pharmacists-can-help-prevent-lipoid-pneumonia
#14
Ann E Cabri, Afoma King, Lee Morrow, Mark A Malesker
OBJECTIVES: To report 2 cases of lipoid pneumonia. SUMMARY: Lipoid pneumonia is an inflammatory process in the lower airways due to the presence of lipid molecules in the alveoli. Exogenous lipoid pneumonia is due to the inhalation or aspiration of fat-containing substances. Historically, mineral oil is the most common medication cause but there have also been several reports of lipoid pneumonia associated with petroleum jelly, medicated vapor rub, and lip glosses...
July 14, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28712196/small-gut-volvulus-a-rare-twist-in-the-setting-of-an-even-rarer-entity-multiple-giant-jejuno-ileal-diverticula
#15
Ayesha Khan, Faheem Khan, Kashif Rafique, Sarwar Khan, Anam Majid, Khalid Khan, Asad Ullah
Small gut volvulus with multiple Jejuno-ileal diverticulosis is an unusual pathology of the small intestine with a scarce number of cases reported so far. It usually goes unnoticed because it is often asymptomatic but complications like diverticulitis, perforation, bleeding or intestinal obstruction can occur in 10-30% of the cases. Mechanical obstruction, if it occurs, can be caused by adhesions or stenosis due to diverticulitis, intussusception at the site of the diverticulum and volvulus of the segment containing the diverticula...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28712179/clinical-spectrum-of-solitary-rectal-ulcer-in-children-presenting-with-per-rectal-bleed
#16
Muhammad Nadeem Anjum, Huma Arshad Cheema, Hassan Suleman Malik, Muhammad Almas Hashmi
BACKGROUND: Solitary rectal ulcer syndrome (SRUS) is a benign and chronic disorder well known in young adults and less common in children. The objective of this study was to determine the frequency and clinical spectrum of solitary rectal ulcer in children with bleeding per rectum. METHODS: This study was conducted in the Department of Paediatric Gastroenterology Hepatology& Nutrition; The Children's Hospital & The Institute of Child Health, Lahore, from January-December 2015...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28712050/spatiotemporal-expression-of-bcl-2-bax-and-neural-cell-apoptosis-in-the-developing-lumbosacral-spinal-cord-of-rat-fetuses-with-anorectal-malformations
#17
Zhonghua Yang, Yuanyuan Geng, Zhiya Yao, Huimin Jia, Yuzuo Bai, Weilin Wang
Fecal incontinence and constipation still remain the major complications after procedures for anorectal malformations (ARMs). Previous studies have demonstrated a decrease of neural cell in lumbosacral spinal cord of ARMs patients and rat models. However, the underlying mechanism remains elusive. In this study, the neural cell apoptosis and Bcl-2/Bax expression were explored during lumbosacral spinal cord development in normal and ARMs fetuses. ARMs rat fetuses were induced by treating pregnant rats with ethylenethiourea on embryonic day 10...
July 15, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28712000/predictors-of-weight-loss-in-early-treated-parkinson-s-disease-from-the-net-pd-ls-1-cohort
#18
Anne-Marie Wills, Ruosha Li, Adriana Pérez, Xuehan Ren, James Boyd
Weight loss is a common symptom of Parkinson's disease and is associated with impaired quality of life. Predictors of weight loss have not been studied in large clinical cohorts. We previously observed an association between change in body mass index and change in Unified Parkinson's Disease Rating Scale (UPDRS) motor and total scores. In this study, we performed a secondary analysis of longitudinal data (1-6 years) from 1619 participants in the NINDS Exploratory Trials in PD Long-term Study-1 (NET-PD LS1) to explore predictors of weight loss in a large prospective clinical trial cohort of early treated Parkinson's disease...
July 15, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28710201/pica-constipation-and-cardiorespiratory-arrest
#19
Inês Mourato Nunes, Ana Isabel Pedroso, Manuel Irimia, Armindo Ramos
No abstract text is available yet for this article.
July 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28708791/self-reported-long-term-autonomic-function-after-laparoscopic-total-mesometrial-resection-for-early-stage-cervical-cancer-a-multicentric-study
#20
Alessandro Lucidi, Swetlana Windemut, Marco Petrillo, Margherita Dessole, Giulio Sozzi, Giuseppe Filiberto Vercellino, Kaven Baessler, Giuseppe Vizzielli, Jalid Sehouli, Giovanni Scambia, Vito Chiantera
OBJECTIVES: This multicentric retrospective study investigates the early and long-term self-reported urinary, bowel, and sexual dysfunctions in early-stage cervical cancer patients who submitted to laparoscopic total mesometrial resection (L-TMMR), total laparoscopic radical hysterectomy, vaginal-assisted laparoscopic radical hysterectomy, and laparoscopic-assisted radical vaginal hysterectomy. METHODS: Cervical cancer patients, FIGO (International Federation of Gynecology and Obstetrics) stage IA2-IB1/IIA1 who submitted to nerve-sparing radical hysterectomy were recruited...
July 13, 2017: International Journal of Gynecological Cancer
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