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Low intensity ultrasound

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https://www.readbyqxmd.com/read/28338392/the-effects-of-low-intensity-therapeutic-ultrasound-litus-on-measurable-outcomes-a-critically-appraised-topic
#1
Sarah Daniels, Gabriela Santiago, Jennifer Cuchna, Bonnie Van Lunen
Therapeutic Ultrasound (US) is a popular modality among healthcare professionals and is used to treat a variety of musculoskeletal conditions.(1) Throughout the past 70 years of clinical use,(2) ultrasound has been shown to be an effective way to decrease pain,(2,3) increase tissue temperature,(4) and decrease tissue stiffness of trigger points,(5) amidst other benefits. Treatment parameters with US are typically high-intensity and occur over a short period of time (minutes). The US machine is large and stationary, forcing patients to be non-mobile for the duration of their treatment...
March 24, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28333964/optimizing-ultrasound-molecular-imaging-of-secreted-frizzled-related-protein-2-expression-in-angiosarcoma
#2
James K Tsuruta, Nicholas P Schaub, Juan D Rojas, Jason Streeter, Nancy Klauber-DeMore, Paul Dayton
Secreted frizzled related protein 2 (SFRP2) is a tumor endothelial marker expressed in angiosarcoma. Previously, we showed ultrasound molecular imaging with SFRP2-targeted contrast increased average video pixel intensity (VI) of angiosarcoma vessels by 2.2 ± 0.6 VI versus streptavidin contrast. We hypothesized that redesigning our contrast agents would increase imaging performance. Improved molecular imaging reagents were created by combining NeutrAvidin™-functionalized microbubbles with biotinylated SFRP2 or IgY control antibodies...
2017: PloS One
https://www.readbyqxmd.com/read/28331357/effectiveness-of-ultrasound-therapy-for-myofascial-pain-syndrome-a-systematic-review-and-meta-analysis
#3
REVIEW
Peng Xia, Xiaoju Wang, Qiang Lin, Kai Cheng, Xueping Li
OBJECTIVE: The objective of this review was to assess the therapeutic effect of ultrasound (US) on myofascial pain syndrome (MPS). DATE SOURCES: PubMed, Embase, and Cochrane Library were searched to find relevant studies from January 1966 to May 2016 using keywords. Four investigators performed the data extraction. STUDY SELECTION: Randomized controlled trials (RCTs) investigating the outcomes of pain and physical function between MPS patients receiving and not receiving US were selected by two researchers independently...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28331074/osteopontin-inhibits-osteoblast-responsiveness-through-the-downregulation-of-focal-adhesion-kinase-mediated-by-the-induction-of-low-molecular-weight-protein-tyrosine-phosphatase
#4
Joji Kusuyama, Kenjiro Bandow, Tomokazu Ohnishi, Mitsuhiro Hisadome, Kaori Shima, Ichiro Semba, Tetsuya Matsuguchi
Osteopontin (OPN) is an osteogenic marker protein. Osteoblast functions are affected by inflammatory cytokines and pathological conditions. OPN is highly expressed in bone legions such as rheumatoid arthritis. However, local regulatory effects of OPN on osteoblasts remain ambiguous. Here, we examined how OPN influences osteoblast responses to mechanical stress and growth factors. Expression of NO synthase 1 (Nos1) and Nos2 was increased by low intensity pulsed ultrasound (LIPUS) in MC3T3-E1 cells and primary osteoblasts...
March 22, 2017: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/28287747/assessment-of-gold-nano-particle-mediated-enhanced-hyperthermia-using-mr-guided-high-intensity-focused-ultrasound-ablation-procedure
#5
Surendra Balaji Devarakonda, Matthew R Myers, Matthew Lanier, Charles Dumoulin, Rupak Kumar Banerjee
High-intensity focused ultrasound (HIFU) has gained increasing popularity as a non-invasive therapeutic procedure to treat solid tumors. However, collateral damage due to the use of high acoustic powers during HIFU procedures remains a challenge. The objective of this study is to assess the utility of using gold nano-particles (gNPs) during HIFU procedures to locally enhance heating at low powers, thereby reducing the likelihood of collateral damage. Phantoms containing tissue-mimicking material (TMM) and physiologically relevant concentrations (0%, 0...
March 13, 2017: Nano Letters
https://www.readbyqxmd.com/read/28287203/-the-iodine-prophylaxis-the-experience-in-the-autonomous-province-of-bolzano-south-tyrol
#6
Fabrizio Franzellin, Lucio Lucchin
Since ancient times in South Tyrol there was evidence of endemic goitre caused by iodine deficiency. In the early 80's an epidemiological research on adults and primary and secondary school children reported in the least a prevalence of goitre from grade 1 B-3 (WHO) of 23,66% (limits WHO >5%) and an urinary iodine of 10,2 µgI/L. Therefore South Tyrol population presented heavy endemic goitre. In 1982 started a generalized iodine prophylaxis with alimentary iodined salt after an intense prevention campaign...
February 2017: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/28284769/sustainable-resuscitation-ultrasound-education-in-a-low-resource-environment-the-kumasi-experience
#7
Chelsea A Tafoya, Matthew J Tafoya, Maxwell Osei-Ampofo, Rockefeller A Oteng, Torben K Becker
BACKGROUND: Point-of-care-ultrasound (POCUS) is an increasingly important tool for emergency physicians and has become a standard component of emergency medicine residency training in high-income countries. Cardiopulmonary ultrasound (CPUS) is emerging as an effective way to quickly and accurately assess patients who present to the emergency department with shock and dyspnea. Use of POCUS, including CPUS, is also becoming more prevalent in low- and middle-income countries (LMICs); however, formal ultrasound training for emergency medicine resident physicians in these settings is not widely available...
March 8, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28283264/uterine-contractility-and-elastography-as-prognostic-factors%C3%A2-for-pregnancy-after-intrauterine-insemination
#8
Nelly Swierkowski-Blanchard, Florence Boitrelle, Laura Alter, Jacqueline Selva, Thibaud Quibel, Antoine Torre
OBJECTIVE: To determine the impact of the frequency and intensity of uterine contractions (UCs) at the time of IUI on subsequent fertility. DESIGN: Observational pilot study. SETTING: University hospital. PATIENT(S): One hundred volunteer women scheduled for IUI between April 2011 and July 2013, in whom UCs were assessed during the ultrasound before IUI. INTERVENTION(S): A two-dimensional sagittal uterus elastography was recorded for 5 minutes...
March 7, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28279642/low-intensity-400%C3%A2-mw-cm-2-500%C3%A2-khz-pulsed-transcranial-ultrasound-preconditioning-may-mitigate-focal-cerebral-ischemia-in-rats
#9
Hangdao Li, Junfeng Sun, Daqu Zhang, Daryl Omire-Mayor, Peter A Lewin, Shanbao Tong
BACKGROUND: Preconditioning methods, which could increase tolerance of brain to subsequent ischemic injuries with a small dose of non-injury stimuli, have gained attention. Capitalizing on noninvasiveness and safety of ultrasound modality, the pulsed transcranial ultrasound stimulation (pTUS) approach may provide a novel treatment for patients with high risk of stroke. OBJECTIVE: This study's goal was to investigate whether the risk of stroke could be minimized or eliminated by prior exposure to low-intensity, pulsed transcranial ultrasound stimulation (pTUS)...
February 27, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28276672/current-adoption-of-lung-ultrasound-in-intensive-care-units-an-italian-multi-centre-survey
#10
Italo Calamai, Massimiliano Greco, Guido Bertolini, Rosario Spina
BACKGROUND: Lung ultrasound (LUS) is a useful tool for assessing lung status in critically ill patients, but is not widely applied in intensive care units (ICUs). The aim of this study was to investigate the use of LUS in Italian ICUs. METHODS: A questionnaire was distributed to 116 ICU representatives belonging to the Italian GiViTI network, participating in a national project on continuous quality of care assessment. The answers to the questionnaire were analysed with the data collected in the course of said project...
March 7, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28276640/prospective-review-of-mesenchymal-stem-cells-differentiation-into-osteoblasts
#11
REVIEW
Priyanka Garg, Matthew M Mazur, Amy C Buck, Meghan E Wandtke, Jiayong Liu, Nabil A Ebraheim
Stem cell research has been a popular topic in the past few decades. This review aims to discuss factors that help regulate, induce, and enhance mesenchymal stem cell (MSC) differentiation into osteoblasts for bone regeneration. The factors analyzed include bone morphogenic protein (BMP), transforming growth factor β (TGF-β), stromal cell-derived factor 1 (SDF-1), insulin-like growth factor type 1 (IGF-1), histone demethylase JMJD3, cyclin dependent kinase 1 (CDK1), fucoidan, Runx2 transcription factor, and TAZ transcriptional coactivator...
March 9, 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28269186/3d-2d-ultrasound-feature-based-registration-for-navigated-prostate-biopsy-a-feasibility-study
#12
Sonia Y Selmi, Emmanuel Promayon, Jocelyne Troccaz
The aim of this paper is to describe a 3D-2D ultrasound feature-based registration method for navigated prostate biopsy and its first results obtained on patient data. A system combining a low-cost tracking system and a 3D-2D registration algorithm was designed. The proposed 3D-2D registration method combines geometric and image-based distances. After extracting features from ultrasound images, 3D and 2D features within a defined distance are matched using an intensity-based function. The results are encouraging and show acceptable errors with simulated transforms applied on ultrasound volumes from real patients...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28264638/to-ignore-or-not-to-ignore-placental-calcifications-on-prenatal-ultrasound-a-systematic-review-and-meta-analysis
#13
Fadi G Mirza, Labib M Ghulmiyyah, Hani Tamim, Maha Makki, Dima Jeha, Anwar Nassar
OBJECTIVE: The human placenta is known to calcify with advancing gestational age, and, in fact, the presence of significant calcifications is one of the components of grade III placenta, typical of late gestation. As such, the presence of significant placental calcifications often prompts obstetric providers to expedite delivery. This practice has been attributed, in part, to the presumed association between grade III placenta and adverse pregnancy outcomes. Such approach, however, can be the source of major anxiety and may lead to unnecessary induction of labor, with its associated predisposition to cesarean delivery as well as a myriad of maternal and neonatal morbidities...
March 6, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28258616/focal-salvage-hifu-in-radiorecurrent-prostate-cancer
#14
A Kanthabalan, M Peters, M Van Vulpen, N McCartan, R G Hindley, A Emara, M C Moore, M Arya, M Emberton, H U Ahmed
OBJECTIVE: To assess short to medium term cancer control rates and side effects of focal salvage High Intensity Focused Ultrasound (HIFU). MATERIALS AND METHODS: A retrospective registry analysis identified 150 men who underwent focal salvage HIFU (Sonablate 500) (November 2006-August 2015). Metastatic disease was excluded using the nodal assessment on the pelvic MRI, a radioisotope bone scan and PET imaging (choline-FDG-PET or Choline PET-CT). In our current clinical practice, metastatic disease must be ruled out by both Choline PET and bone scan...
March 4, 2017: BJU International
https://www.readbyqxmd.com/read/28258474/impact-of-ultrasonography-on-treatment-decision-in-rheumatoid-arthritis-the-impulsar-study
#15
Cèsar Díaz-Torné, Carme Moragues, Elide Toniolo, Carme Geli, Iván Castellví, Patricia Moya, Ignasi Gich, Josep M Llobet
Ultrasonography (US) has shown to be more sensitive than physical examination for diagnosis and assessment of rheumatoid arthritis (RA). It is also a useful approach for accurate monitoring and intensive treatment adjustment. However, there is limited information concerning the impact of US on therapeutic decision-making in routine daily practice. A single-center cross-sectional study in routine daily practice was conducted to determine the percentage of patients with rheumatoid arthritis (RA) in which treatment decision was modified on the basis of results of musculoskeletal ultrasonography...
March 3, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28257990/extracellular-matrix-remodeling-in-vivo-for-enhancing-tumor-targeting-efficiency-of-nanoparticle-drug-carriers-using-the-pulsed-high-intensity-focused-ultrasound
#16
Sangmin Lee, Hyounkoo Han, Heebeom Koo, Jin Hee Na, Hong Yeol Yoon, Kyung Eun Lee, Hyukjin Lee, Hyuncheol Kim, Ick Chan Kwon, Kwangmeyung Kim
Dense and stiff extracellular matrix (ECM) in heterogeneous tumor tissues can inhibit deep penetration of nanoparticle drug carriers and decreases their therapeutic efficacy. Herein, we suggest the ECM remodeling strategy by the pulsed high intensity focused ultrasound (Pulsed-HIFU) technology for enhanced tumor-targeting of nanoparticles. First, we clearly observed that the tumor-targeting efficacy and tissue penetration of intravenously injected Cy5.5-labled glycol chitosan nanoparticles (Cy5.5-CNPs) were greatly inhibited in tumor tissue containing high collagen and hyaluronan contents in ECM-rich A549 tumor-bearing mice, compared to in ECM-less SCC7...
February 28, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28244011/focused-ultrasound-an-emerging-therapeutic-modality-for-neurologic-disease
#17
Paul S Fishman, Victor Frenkel
Therapeutic ultrasound is only beginning to be applied to neurologic conditions, but the potential of this modality for a wide spectrum of brain applications is high. Engineering advances now allow sound waves to be targeted through the skull to a brain region selected with real time magnetic resonance imaging and thermography, using a commercial array of focused emitters. High intensities of sonic energy can create a coagulation lesion similar to that of older radiofrequency stereotactic methods, but without opening the skull...
February 27, 2017: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://www.readbyqxmd.com/read/28239034/effects-of-low-intensity-pulsed-ultrasound-on-osteoclasts-analysis-with-goldfish-scales-as-a-model-of-bone
#18
Taizo Hanmoto, Yoshiaki Tabuchi, Mika Ikegame, Takashi Kondo, Kei-Ichiro Kitamura, Masato Endo, Isao Kobayashi, Hiroyuki Mishima, Toshio Sekiguchi, Makoto Urata, Azusa Seki, Sachiko Yano, Atsuhiko Hattori, Nobuo Suzuki
The effects of low-intensity pulsed ultrasound (LIPUS) on osteoclastogenesis were examined using fish scales that had both osteoclasts and osteoblasts. The binding of the receptor activator of NF-κB ligand (RANKL) in osteoblasts to the receptor activator of NF-κB (RANK) in osteoclasts induced osteoclastogenesis. Therefore, we focused on RANK/RANKL signaling. After 6 h of incubation following LIPUS treatment, mRNA expression of RANKL increased significantly. Resulting from the increased RANKL mRNA level, the expression of transcription-regulating factors significantly increased after 6 h of incubation, and then the mRNA expression of functional genes was significantly up-regulated after 12 h of incubation...
2017: Biomedical Research
https://www.readbyqxmd.com/read/28238588/rest-stress-limb-perfusion-imaging-in-humans-with-contrast-ultrasound-using-intermediate-power-imaging-and-microbubbles-resistant-to-inertial-cavitation
#19
Brian P Davidson, James Hodovan, J Todd Belcik, Federico Moccetti, Aris Xie, Azzdine Y Ammi, Jonathan R Lindner
BACKGROUND: Contrast-enhanced ultrasound (CEU) limb perfusion imaging is a promising approach for evaluating peripheral artery disease (PAD). However, low signal enhancement in skeletal muscle has necessitated high-power intermittent imaging algorithms, which are not clinically feasible. We hypothesized that CEU using a combination of intermediate power and a contrast agent resistant to inertial cavitation would allow real-time limb stress perfusion imaging. METHODS: In normal volunteers, CEU of the calf skeletal muscle was performed on separate days with Sonazoid, Optison, or Definity...
February 23, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28236581/single-simultaneous-and-sequential-applications-of-ultrasonic-frequencies-for-the-elimination-of-ibuprofen-in-water
#20
Asu Ziylan-Yavas, Nilsun H Ince
The study is about the assessment of single and multi-frequency operations for the overall degradation of a widely consumed analgesic pharmaceutical-ibuprofen (IBP). The selected frequencies were in the range of 20-1130kHz emissions coming from probes, baths and piezo-electric transducers attached to plate-type devices. Multi-frequency operations were applied either simultaneously as "duals", or sequentially at fixed time intervals; and the total reaction time in all operations was 30-min. The work also covers evaluation of the effect of zero-valent iron (ZVI) on the efficiency of the degradation process and the performance of the reaction systems...
January 26, 2017: Ultrasonics Sonochemistry
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