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Low intensity ultrasound

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https://www.readbyqxmd.com/read/28430035/noninvasive-neuromodulation-and-thalamic-mapping-with-low-intensity-focused-ultrasound
#1
Robert F Dallapiazza, Kelsie F Timbie, Stephen Holmberg, Jeremy Gatesman, M Beatriz Lopes, Richard J Price, G Wilson Miller, W Jeffrey Elias
OBJECTIVE Ultrasound can be precisely focused through the intact human skull to target deep regions of the brain for stereotactic ablations. Acoustic energy at much lower intensities is capable of both exciting and inhibiting neural tissues without causing tissue heating or damage. The objective of this study was to demonstrate the effects of low-intensity focused ultrasound (LIFU) for neuromodulation and selective mapping in the thalamus of a large-brain animal. METHODS Ten Yorkshire swine ( Sus scrofa domesticus) were used in this study...
April 21, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28427670/estimation-of-the-distribution-of-low-intensity-ultrasound-mechanical-index-as-a-parameter-affecting-the-proliferation-of-spermatogonia-stem-cells-in-vitro
#2
Zeinab Hormozi Moghaddam, Manijhe Mokhtari-Dizaji, Mansoureh Movahedin, Mohammad Ehsan Ravari
Considering the use of physical and mechanical stimulation, such as low-intensity ultrasound for proliferation and differentiation of stem cells, it is essential to understand the physical and acoustical mechanisms of acoustic waves in vitro. Mechanical index is used for quantifying acoustic cavitation and the relationship between acoustic pressure and the frequency. In this study, modeling of the mechanical index was applied to provide treatment protocol and to understand the effective physical processes on reproducibility of stem cells...
July 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28427664/ultrasonic-irradiation-of-low-intensity-with-a-mode-of-sweeping-frequency-enhances-the-membrane-permeability-and-cell-growth-rate-of-candida-tropicalis
#3
Guoping Huang, Yingxiu Tang, Ling Sun, Huan Xing, Haile Ma, Ronghai He
Here we report the enhancement of both cellular permeability and cell growth rate of Candida tropicalis after treatment with the ultrasonic irradiation of low intensity using a mode of sweeping frequency (UILS) generated by a self-developed ultrasonic device in our lab. After the ultrasonic treatment, remarkable biomass enhancement of the yeast was observed; the hyphae became significantly longer; the seeped cellular protein and nucleic acid from the yeast increased and the cellular Ca(2+) content became lower...
July 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28427634/enhanced-porosity-and-permeability-of-three-dimensional-alginate-scaffolds-via-acoustic-microstreaming-induced-by-low-intensity-pulsed-ultrasound
#4
Gepu Guo, Yong Ma, Yang Guo, Chunbing Zhang, Xiasheng Guo, Juan Tu, Alfred C H Yu, Junru Wu, Dong Zhang
The shear stress resulting from the microstreaming induced by low-intensity pulsed ultrasound (LIPUS) has been often used to improve the permeability of cell membrane or porous engineering scaffolds. In the present study, three-dimensional (3-D) scaffold culture systems were constituted to simulate the in vivo microenvironment, providing benefits for cell growth. In order to investigate the mechanism underlying the enhanced porosity and permeability of the 3-D alginate scaffolds by using LIPUS with varied acoustic intensities, two quantitative imaging techniques (i...
July 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28427614/production-of-graphene-quantum-dots-by-ultrasound-assisted-exfoliation-in-supercritical-co2-h2o-medium
#5
Hanyang Gao, Chen Xue, Guoxin Hu, Kunxu Zhu
In this research, three kinds of graphene quantum dots (GQDs)-pristine graphene quantum dots (PGQDs), expanded graphene quantum dots (EGQDs) and graphene oxide quantum dots (GOQDs)-were produced from natural graphite, expanded graphite, and oxide graphite respectively in an ultrasound-assisted supercritical CO2 (scCO2)/H2O system. The effects of aqueous solution content ratio, system pressure, and ultrasonic power on the yields of different kinds of GQDs were investigated. According to these experiment results, the combination of the intense knocking force generated from high-pressure acoustic cavitation in a scCO2/H2O system and the superior penetration ability of scCO2 was considered to be the key to the successful exfoliation of such tiny pieces from bulk graphite...
July 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28427611/experimental-study-on-the-influence-of-low-frequency-and-low-intensity-ultrasound-on-the-permeability-of-the-mycobacterium-smegmatis-cytoderm-and-potentiation-with-levofloxacin
#6
Yu Dong, Hang Su, Hexun Jiang, Huimin Zheng, Yonghong Du, Junru Wu, Dairong Li
Tuberculosis is an infectious disease caused by the bacterium M. tuberculosis. The aim of this study was to investigate the bactericidal effect and underlying mechanisms of low-frequency and low-intensity ultrasound combined with levofloxacin treatment against M. smegmatis (a surrogate of M. tuberculosis). As part of this study, M. smegmatis was continuously irradiated with low frequency ultrasound (42kHz) using several different doses whereby both intensity (0.138, 0.190 and 0.329W/cm(2)) and exposure time (5, 15 and 20min) were varied...
July 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28412225/enhancing-tissue-permeability-with-mri-guided-preclinical-focused-ultrasound-system-in-rabbit-muscle-from-normal-tissue-to-vx2-tumor
#7
Yao Sun, Xiaobing Xiong, Darpan Pandya, Youngkyoo Jung, Akiva Mintz, Satoru Hayasaka, Thaddeus J Wadas, King C P Li
High Intensity Focused Ultrasound (HIFU) is an emerging noninvasive, nonionizing physical energy based modality to ablate solid tumors with high power, or increase local permeability in tissues/tumors in pulsed mode with relatively low power. Compared with traditional ablative HIFU, nondestructive pulsed HIFU (pHIFU) is present in the majority of novel applications recently developed for enhancing the delivery of drugs and genes. Previous studies have demonstrated the capability of pHIFU to change tissue local permeability for enhanced drug delivery in both mouse tumors and mouse muscle...
April 12, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28402924/remote-tele-mentored-ultrasound-for-non-physician-learners-using-facetime-a-feasibility-study-in-a-low-income-country
#8
Thomas E Robertson, Andrea R Levine, Avelino C Verceles, Jessica A Buchner, James H Lantry, Alfred Papali, Marc T Zubrow, L Nathalie Colas, Marc E Augustin, Michael T McCurdy
PURPOSE: Ultrasound (US) is a burgeoning diagnostic tool and is often the only available imaging modality in low- and middle-income countries (LMICs). However, bedside providers often lack training to acquire or interpret US images. We conducted a study to determine if a remote tele-intensivist could mentor geographically removed LMIC providers to obtain quality and clinically useful US images. MATERIALS AND METHODS: Nine Haitian non-physician health care workers received a 20-minute training on basic US techniques...
April 7, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28402868/age-related-differences-in-twitch-properties-and-muscle-activation-of-the-first-dorsal-interosseous
#9
Jonathan D Miller, Trent J Herda, Michael A Trevino, Adam J Sterczala, Anthony B Ciccone, Justin X Nicoll
OBJECTIVE: To examine twitch force potentiation and twitch contraction duration, as well as electromyographic amplitude (EMGRMS) and motor unit mean firing rates (MFR) at targeted forces between young and old individuals in the first dorsal interosseous (FDI). Ultrasonography was used to assess muscle quality. METHODS: Twenty-two young (YG) (age=22.6±2.7years) and 14 older (OD) (age=62.1±4.7years) individuals completed conditioning contractions at 10% and 50% maximal voluntary contraction, (MVC) during which EMGRMS and MFRs were assessed...
March 24, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28391752/low-intensity-pulsed-ultrasound-for-nonoperative-treatment-of-scaphoid-nonunions-a-meta-analysis
#10
Edward W Seger, Julio J Jauregui, Steven A Horton, Gerardo Davalos, Erika Kuehn, Michael A Stracher
BACKGROUND: Scaphoid fractures progress to nonunion rates of up to 15% when non-displaced, and are even more frequent when the fracture is displaced. Standard treatment in these cases is surgery; however, individuals unable to undergo this operation, or for those who wish to try more conservative measures, there may be benefit from nonoperative options. Of these, low-intensity pulsed ultrasound (LIPUS) has been shown to improve fracture nonunion healing. The purpose of this study was to perform a comprehensive meta-analysis of relevant literature to determine success of the use of LIPUS for treatment of scaphoid nonunion...
April 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28391748/small-for-gestational-age-babies-of-term-low-risk-pregnancies-does-antenatal-detection-matter
#11
Catarina Policiano, Andreia Fonseca, Jorge M Mendes, Nuno Clode, Luís M Graça
OBJECTIVES: To compare delivery route and admission rate to neonatal intensive care unit between small- and appropriate-for-gestational-age babies among term low risk pregnancies. METHODS: A retrospective study was conducted using the database of deliveries in 2014 at a tertiary hospital. Babies delivered at ≥ 37 weeks with birthweight < 10(th) centile were considered small-for-gestational-age and > 90(th) centile were considered large-for-gestational-age...
April 10, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28391380/low-intensity-pulsed-ultrasound-is-effective-for-progressive-stage-lumbar-spondylolysis-with-mri-high-signal-change
#12
Hideyuki Arima, Yoshiji Suzuki, Daisuke Togawa, Yuki Mihara, Hideyuki Murata, Yukihiro Matsuyama
PURPOSE: This study aimed to investigate the treatment effects of low-intensity pulsed ultrasound (LIPUS) on progressive-stage spondylolysis. Spondylolysis is a stress fracture of the pars interarticularis. Based on the results of computed tomography, spondylolysis was classified into three categories: early, progressive, and terminal. Bone healing was prolonged or not obtained in progressive-stage spondylolysis. The progression of spondylolysis to nonunion has been associated with an increased incidence of spondylolisthesis...
April 8, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28386479/bedside-ultrasound-measurement-of-rectus-femoris-a-tutorial-for-the-nutrition-support-clinician
#13
Carlos Alfredo Galindo Martín, Enrique Monares Zepeda, Octavio Augusto Lescas Méndez
Intensive care unit acquired weakness is a long-term consequence after critical illness; it has been related to muscle atrophy and can be considered as one of the main nutritional support challenges at the intensive care unit. Measuring muscle mass by image techniques has become a new area of research for the nutritional support field, extending our knowledge about muscle wasting and the impact of nutritional approaches in the critical care setting, although currently there is no universally accepted technique to perform muscle measurements by ultrasound...
2017: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/28385939/low-intensity-pulsed-ultrasound-does-not-influence-bone-healing-by-distraction-osteogenesis-a-multicentre-double-blind-randomised-control-trial
#14
A H R W Simpson, G Keenan, S Nayagam, R M Atkins, D Marsh, N D Clement
AIMS: The aim of this double-blind prospective randomised controlled trial was to assess whether low intensity pulsed ultrasound (LIPUS) accelerated or enhanced the rate of bone healing in adult patients undergoing distraction osteogenesis. PATIENTS AND METHODS: A total of 62 adult patients undergoing limb lengthening or bone transport by distraction osteogenesis were randomised to treatment with either an active (n = 32) or a placebo (n = 30) ultrasound device...
April 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28382599/diagnostic-accuracy-of-quantitative-neuromuscular-ultrasound-for-the-diagnosis-of-intensive-care-unit-acquired-weakness-a-cross-sectional-observational-study
#15
Esther Witteveen, Juultje Sommers, Luuk Wieske, Jonne Doorduin, Nens van Alfen, Marcus J Schultz, Ivo N van Schaik, Janneke Horn, Camiel Verhamme
BACKGROUND: Neuromuscular ultrasound is a noninvasive investigation, which can be easily performed at the bedside on the ICU. A reduction in muscle thickness and increase in echo intensity over time have been described in ICU patients, but the relation to ICU-acquired weakness (ICU-AW) is unknown. We hypothesized that quantitative assessment of muscle and nerve parameters with ultrasound can differentiate between patients with and without ICU-AW. The aim of this cross-sectional study was to investigate the diagnostic accuracy of neuromuscular ultrasound for diagnosing ICU-AW...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28378753/low-intensity-pulsed-ultrasound-lipus-prevents-periprosthetic-inflammatory-loosening-through-fbxl2-traf6-ubiquitination-pathway
#16
Xiang Zhao, Gangsheng Zhao, Zhongli Shi, Chenhe Zhou, Yunlin Chen, Bin Hu, Shigui Yan
Previous studies have shown that Low intensity pulsed ultrasound(LIPUS) prevents polyethylene-debris-induced periprosthetic loosening in vivo, but the details of the mechanism by which it does so remain unclear. In this article, we used polyethylene debris induced RAW 264.7 cells as the in vitro model, and tested the effect of LIPUS on this model. Changes in the level of inflammatory cytokines, cell proliferation, and apoptosis were assessed. Gene overexpression and siRNA technique were applied, and the levels of expression of FBXL2, TRAF6, ERK, and related inflammatory cytokines were also measured...
April 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28373480/salvage-robotic-assisted-laparoscopic-radical-prostatectomy-experience-with-14-cases
#17
Yen-Chuan Ou, Sheng-Chun Hung, Li-Hua Hwang, Chun-Kuang Yang, Siu-Wan Hung, Min-Che Tung
AIM: To report the outcomes of salvage robot-assisted radical prostatectomy (S-RaRP). PATIENTS AND METHODS: Fourteen patients underwent S-RaRP. The mean initial prostatic-specific antigen level was 14.3 ng/ml and mean Gleason score was 6.93. Initial definitive treatment was external irradiation in 11 cases, cyberknife in two, and high-intensity focused ultrasound in one. Time from definitive treatment to S-RaRP was a mean of 36.5 months. RESULTS: The mean console time was 134...
April 2017: Anticancer Research
https://www.readbyqxmd.com/read/28371793/ultrasound-standard-plane-detection-using-a-composite-neural-network-framework
#18
Hao Chen, Lingyun Wu, Qi Dou, Jing Qin, Shengli Li, Jie-Zhi Cheng, Dong Ni, Pheng-Ann Heng
Ultrasound (US) imaging is a widely used screening tool for obstetric examination and diagnosis. Accurate acquisition of fetal standard planes with key anatomical structures is very crucial for substantial biometric measurement and diagnosis. However, the standard plane acquisition is a labor-intensive task and requires operator equipped with a thorough knowledge of fetal anatomy. Therefore, automatic approaches are highly demanded in clinical practice to alleviate the workload and boost the examination efficiency...
March 30, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28362605/low-cost-3d-flow-estimation-of-blood-with-clutter
#19
Siyuan Wei, Ming Yang, Jian Zhou, Richard Sampson, Oliver Kripfgans, Brian Fowlkes, Thomas Wenisch, Chaitali Chakrabarti
Volumetric flow rate estimation is an important ultrasound medical imaging modality that is used for diagnosing cardiovascular diseases. Flow rates are obtained by integrating velocity estimates over a cross-sectional plane. Speckle-tracking is a promising approach that overcomes the angle dependency of traditional Doppler methods, but suffers from poor lateral resolution. Recent work improves lateral velocity estimation accuracy by reconstructing a synthetic lateral phase signal. However, the estimation accuracy of such approaches is compromised by the presence of clutter...
March 2, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28361079/ultrasound-to-assess-diaphragmatic-function-in-the-critically-ill-a-critical-perspective
#20
EDITORIAL
Mark Haaksma, Pieter Roel Tuinman, Leo Heunks
Ultrasound of the diaphragm in critically ill patients has become a diagnostic technique of emerging interest among clinicians and scientists. The advantages include that it is widely available, non-invasive and examination can be performed after relatively short training and at low costs. It is used to estimate muscle mass by measurement of muscle thickness and diagnose weakness by the assessment of diaphragm movement during unassisted breathing. Thickening of the muscle during inspiration has been used to quantify force generation...
March 2017: Annals of Translational Medicine
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