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Low intensity ultrasound

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https://www.readbyqxmd.com/read/27913777/risk-factors-for-major-bleeding-in-the-seattle-ii-trial
#1
Immad Sadiq, Samuel Z Goldhaber, Ping-Yu Liu, Gregory Piazza
Ultrasound-facilitated, catheter-directed, low-dose fibrinolysis minimizes the risk of intracranial bleeding compared with systemic full-dose fibrinolytic therapy for pulmonary embolism (PE). However, major bleeding is nevertheless a potential complication. We analyzed the 150-patient SEATTLE II trial of submassive and massive PE patients to describe those who suffered major bleeding events following ultrasound-facilitated, catheter-directed, low-dose fibrinolysis and to identify risk factors for bleeding. Major bleeding was defined as GUSTO severe/life-threatening or moderate bleeds within 72 hours of initiation of the procedure...
December 1, 2016: Vascular Medicine
https://www.readbyqxmd.com/read/27908581/sonodynamic-inactivation-of-gram-positive-and-gram-negative-bacteria-using-a-rose-bengal-antimicrobial-peptide-conjugate
#2
David Costley, Heather Nesbitt, Nigel Ternan, James Dooley, Ying-Ying Huang, Michael R Hamblin, Anthony P McHale, John F Callan
Combating antimicrobial resistance is one of the most serious public health challenges facing society today. The development of new antibiotics or alternative techniques that can help combat antimicrobial resistance is being prioritised by many governments and stakeholders across the globe. Antimicrobial photodynamic therapy is one such technique that has received considerable attention but is limited by the inability of light to penetrate through human tissue, reducing its effectiveness when used to treat deep-seated infections...
November 17, 2016: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/27884775/tuning-acoustic-and-mechanical-properties-of-materials-for-ultrasound-phantoms-and-smart-substrates-for-cell-cultures
#3
A Cafarelli, A Verbeni, A Poliziani, P Dario, A Menciassi, L Ricotti
: Materials with tailored acoustic properties are of great interest for both the development of tissue-mimicking phantoms for ultrasound tests and smart scaffolds for ultrasound mediated tissue engineering and regenerative medicine. In this study, we assessed the acoustic properties (speed of sound, acoustic impedance and attenuation coefficient) of three different materials (agarose, polyacrylamide and polydimethylsiloxane) at different concentrations or cross-linking levels and doped with different concentrations of barium titanate ceramic nanoparticles...
November 21, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/27883051/lipid-coated-microbubbles-and-low-intensity-pulsed-ultrasound-enhance-chondrogenesis-of-human-mesenchymal-stem-cells-in-3d-printed-scaffolds
#4
Mitra Aliabouzar, Lijie Grace Zhang, Kausik Sarkar
Lipid-coated microbubbles are used to enhance ultrasound imaging and drug delivery. Here we apply these microbubbles along with low intensity pulsed ultrasound (LIPUS) for the first time to enhance proliferation and chondrogenic differentiation of human mesenchymal stem cells (hMSCs) in a 3D printed poly-(ethylene glycol)-diacrylate (PEG-DA) hydrogel scaffold. The hMSC proliferation increased up to 40% after 5 days of culture in the presence of 0.5% (v/v) microbubbles and LIPUS in contrast to 18% with LIPUS alone...
November 24, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27870804/the-effects-of-low-load-motor-control-exercises-and-a-high-load-lifting-exercise-on-lumbar-multifidus-thickness-a-randomized-controlled-trial
#5
Lars Berglund, Björn Aasa, Peter Michaelson, Ulrika Aasa
STUDY DESIGN: Randomized controlled trial OBJECTIVE.: The aim of this study was to compare the effects of low-load motor control exercises and a high-load lifting exercise, on lumbar multifidus (LM) thickness on either side of the spine and whether the effects are affected by pain intensity or change in pain intensity, among patients with nociceptive mechanical LBP. SUMMARY OF BACKGROUND DATA: There is evidence that patients with low back pain may have a decreased size of the (LM) muscles with an asymmetry between sides in the lower back...
November 18, 2016: Spine
https://www.readbyqxmd.com/read/27853727/effects-of-low-intensity-continuous-ultrasound-on-hematological-parameters-of-rats
#6
M Mehrpour, A Shakeri-Zadeh, P Basir, B Jamei, H Ghaheri, M B Shiran
BACKGROUND: Low intensity ultrasound (US) has some well-known bio-effects which are of great importance to be considered. Objective: We conducted the present study to investigate the effects of low intensity continuous ultrasound on blood cells count in rat. METHODS: Rats were anesthetized and blood samples were collected before US exposure. Then, they were exposed to US with nominal intensity of 0.2 W/cm2 at frequency of 3 MHz for a period of 10 minutes and this protocol was repeated for 7 days...
September 2016: Journal of Biomedical Physics & Engineering
https://www.readbyqxmd.com/read/27828799/a-pilot-assessment-of-3-point-of-care-strategies-for-diagnosis-of-perioperative-lung-pathology
#7
John W Ford, Johan Heiberg, Anthony P Brennan, Colin F Royse, David J Canty, Doa El-Ansary, Alistair G Royse
BACKGROUND: Lung ultrasonography is superior to clinical examination and chest X-ray (CXR) in diagnosis of acute respiratory pathology in the emergency and critical care setting and after cardiothoracic surgery in intensive care. Lung ultrasound may be useful before cardiothoracic surgery and after discharge from intensive care, but the proportion of significant respiratory pathology in this setting is unknown and may be too low to justify its routine use. The aim of this study was to determine the proportion of clinically significant respiratory pathology detectable with CXR, clinical examination, and lung ultrasound in patients on the ward before and after cardiothoracic surgery...
November 8, 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27824970/a-pediatric-malignant-paraganglioma-and-brief-review-of-the-literature
#8
Jinhua Zi, Chao Ma, Changyun Xu, Yongli Bai
: A 10 years old boy presented to our hospital complaining of belly pain. He had a retroperitoneal mass diagnosed by ultrasound 3 days before. During that time he was found to have slight hypertension. Computed tomography (CT) showed a left retroperitoneal mass with edge enhancement and central necrosis indicating pheochromocytoma (PCC). Vanillymandelic acid (VMA) in the 24 hours urine sample was not elevated. Pheochromocytoma was suspected given his hypertension and the ultrasound and CT findings...
November 8, 2016: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/27818118/-medical-induced-abortion
#9
K Bettahar, A Pinton, T Boisramé, V Cavillon, S Wylomanski, I Nisand, D Hassoun
OBJECTIVE: Updated clinical recommendations for medical induced abortion procedure. METHODS: A systematic review of French and English literature, reviewing the evidence relating to the provision of medical induced abortion was carried out on PubMed, Cochrane Library and international scientific societies recommendations. RESULTS: The effectiveness of medical abortion is higher than 95% when the protocols are adjusted to gestational age (EL1)...
November 3, 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/27817969/quantification-of-temperature-rise-within-the-lens-of-the-porcine-eye-caused-by-ultrasound-insonation
#10
Randy L King, Yunbo Liu, Gerald R Harris
The soft tissue thermal index defined in the Output Display Standard is not applicable to eye exposures because of unique eye properties such as high ultrasound absorption in the lens and orbital fat. To address this potential safety issue, the U.S. Food and Drug Administration has recommended a maximum exposure level for ophthalmic exams of 50 mW/cm(2) (derated spatial-peak temporal-average intensity, ISPTA.3) based on a model of ultrasound propagation in the eye. To gain a better understanding of actual temperature rise as a function of ISPTA...
November 3, 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/27816247/the-effect-of-low-intensity-ultrasound-on-brain-derived-neurotropic-factor-expression-in-a-rat-sciatic-nerve-crushed-injury-model
#11
Xue-Jun Ni, Xiao-Dong Wang, Ya-Hong Zhao, Hua-Lin Sun, Yu-Ming Hu, Jian Yao, Yi Wang
Low-intensity ultrasound (LIU) can improve nerve regeneration and functional recovery after peripheral nerve crush injury, but the underlying mechanism is not clear. The objective of this study was to examine the effects of LIU on rat sciatic crush injury and to investigate a possible molecular mechanism. Adult male Sprague-Dawley rats underwent left sciatic nerve crush surgery and were then randomized into two groups: a treatment group that received LIU every other d, and a control group that received sham exposure...
November 2, 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/27814934/effect-of-low-intensity-pulsed-ultrasound-on-a-rat-model-of-dentin-dental-pulp-injury-and-repair
#12
Fei Wang, Yueheng Li, Zhengyan Yang, Keke Lu, Jing Zuo, Zhi Zhou
This study investigated histopathologic changes in dental pulp after treatment with low-intensity pulsed ultrasound (LIPUS). Fifty rats were randomly divided into an experimental group (n = 25) and a blank control group (n = 25). In the experimental group, a cavity was prepared in the bilateral maxillary first molars. The upper right first molars were stimulated with LIPUS (30 mW/cm(2), 1.5 MHz) for 20 min/d. The cavities prepared in the left teeth were used as experimental controls (i.e., no LIPUS)...
November 1, 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/27807500/recent-advances-of-sonodynamic-therapy-in-cancer-treatment
#13
Guo-Yun Wan, Yang Liu, Bo-Wei Chen, Yuan-Yuan Liu, Yin-Song Wang, Ning Zhang
Sonodynamic therapy (SDT) is an emerging approach that involves a combination of low-intensity ultrasound and specialized chemical agents known as sonosensitizers. Ultrasound can penetrate deeply into tissues and can be focused into a small region of a tumor to activate a sonosensitizer which offers the possibility of non-invasively eradicating solid tumors in a site-directed manner. In this article, we critically reviewed the currently accepted mechanisms of sonodynamic action and summarized the classification of sonosensitizers...
September 2016: Cancer Biology & Medicine
https://www.readbyqxmd.com/read/27797787/re-evaluation-of-low-intensity-pulsed-ultrasound-in-treatment-of-tibial-fractures-trust-randomized-clinical-trial
#14
Jason W Busse, Mohit Bhandari, Thomas A Einhorn, Emil Schemitsch, James D Heckman, Paul Tornetta, Kwok-Sui Leung, Diane Heels-Ansdell, Sun Makosso-Kallyth, Gregory J Della Rocca, Clifford B Jones, Gordon H Guyatt
OBJECTIVE:  To determine whether low intensity pulsed ultrasound (LIPUS), compared with sham treatment, accelerates functional recovery and radiographic healing in patients with operatively managed tibial fractures. DESIGN:  A concealed, randomized, blinded, sham controlled clinical trial with a parallel group design of 501 patients, enrolled between October 2008 and September 2012, and followed for one year. SETTING:  43 North American academic trauma centers...
October 25, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27794165/a-novel-transcutaneous-non-focused-ultrasound-energy-delivering-device-is-able-to-induce-subcutaneous-adipose-tissue-destruction-in-an-animal-model
#15
Assi Levi, Dan Ben Amitai, Moshe Lapidoth
BACKGROUND AND OBJECTIVES: The understanding that adipocytes are greatly influenced by thermal changes combined with the advancement of non-invasive ultrasound technologies have led to the application of ultrasound as an energy source to induce thermal fat destruction. While application of high intensity focused, ultrasound energy have been widely explored, there is far less information regarding the effects of non-focused ultrasound on adipose tissue. The purpose of this study was to characterize the effects of a novel transcutaneous, multi-elements, non-focused ultrasound energy regimen in an animal model, as a proof-of-concept of its potential to treat non-invasive subcutaneous benign tumors...
October 29, 2016: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/27785362/low-intensity-pulsed-ultrasound-stimulation-in-different-regions-in-the-viability-of-myocutaneous-flaps
#16
Fernanda Luiza de Almeida Albuquerque, Lais Mara Siqueira das Neves, Elaine Caldeira de Oliveira Guirro
BACKGROUND: Low-intensity pulsed ultrasound (LIPUS) has presented good results in the healing of chronic wounds. The objective of this study was to compare the effect of LIPUS on the viability of transverse rectus abdominal muscle (TRAM) flap in different regions (central and epigastric) in rats. METHODS: Twenty-one Wistar male rats were homogeneously distributed into three groups as follows: group 1 (control), animals submitted to surgery only; group 2, animals submitted to surgery and application of LIPUS at the center of the flap; and group 3, animals submitted to surgery and application of LIPUS at the flap area corresponding to the right inferior epigastric artery pedicle...
2016: Journal of Therapeutic Ultrasound
https://www.readbyqxmd.com/read/27780808/low-intensity-pulsed-ultrasound-for-fractures-of-the-tibial-shaft
#17
EDITORIAL
X L Griffin
No abstract text is available yet for this article.
October 25, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27777197/-effect-of-low-dose-focused-ultrasound-pre-irradiation-versus-microbubbles-for-enhancing-high-intensity-focused-ultrasound-ablation-of-vx2-hepatic-tumor-in-rabbits
#18
Yi Zhang, Chao Yang, Jian-Zhong Zou, Fei Chen, Xia Ou, Hai-Rong Zou, Yan Wang
OBJECTIVE: To compare the effect of low-dose focused ultrasound pre-irradiation and microbubbles for enhancing the ablation effect of high intensity focused ultrasound (HIFU) on VX2 hepatic tumor in rabbits. METHODS: Fifty-five rabbits bearing VX2 hepatic tumor were randomly divided into low-dose pre-irradiation + HIFU ablation group, microbubbles+HIFU ablation group, and HIFU ablation group for corresponding treatments. The pathological changes in the tumors after low-dose irradiation, time for HIFU ablation, tumor volume with coagulative necrosis, energy efficiency factor (EEF), pathological changes in the ablated tumor, and sound channel of HIFU ablation were observed...
October 20, 2016: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/27774951/-low-intensity-pulsed-ultrasound-promotes-extracellular-matrix-synthesis-of-human-osteoarthritis-chondrocytes
#19
Dengkui DU, Shirong Chen, Gang Yi, Pan Wang, Ying Tang, Liwen Zheng, Junnan Chen
Objective To investigate the effect of low-intensity pulsed ultrasound (LIPUS) on the extracellular matrix synthesis of human osteoarthritis (OA) chondrocytes and explore the underlying mechanism. Methods Human osteoarthritis chondrocytes were collected from abandoned articular cartilage. Then the cells were cultured and identified by toluidine blue staining and immunocytochemical staining of type 2 collagen. The passage 2 cells were randomly divided into 3 groups: control OA group, 30 mW/cm(2) LIPUS-treated OA group, 30 mW/cm(2) LIPUS combined with 5 μmol/L LY294002-treated OA group...
November 2016: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
https://www.readbyqxmd.com/read/27774787/template-free-synthesis-of-hollow-porous-organosilica-fe3o4-hybrid-nanocapsules-towards-mri-guided-high-intensity-focused-ultrasound-therapy
#20
Ming Ma, Fei Yan, Minghua Yao, Zijun Wei, Dongliang Zhou, Heliang Yao, Hairong Zheng, Hangrong Chen, Jianlin Shi
Entirely differing from the common templating-based multistep strategy in fabricating multifunctional hollow mesoporous silica nanoparticles (HMSNs), a facile and template-free synthetic strategy has been established in constructing a unique hollow/mesoporous organosilica nanocapsule concurrently encapsulating both isopentyl acetate (PEA) liquid and superparamagnetic iron oxides inside (denoted as PEA@OSNCs). This novel material exhibits ultrasmall and uniform particle size (~82 nm), high surface area (~534 m2 g-1) and excellent colloidal stability in aqueous solution...
October 24, 2016: ACS Applied Materials & Interfaces
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