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https://www.readbyqxmd.com/read/28228000/c60-fullerene-as-promising-therapeutic-agent-for-the-prevention-and-correction-of-skeletal-muscle-functioning-at-ischemic-injury
#1
D M Nozdrenko, D O Zavodovskyi, T Yu Matvienko, S Yu Zay, K I Bogutska, Yu I Prylutskyy, U Ritter, P Scharff
The therapeutic effect of pristine C60 fullerene aqueous colloid solution (C60FAS) on the functioning of the rat soleus muscle at ischemic injury depending on the time of the general pathogenesis of muscular system and method of administration C60FAS in vivo was investigated. It was found that intravenous administration of C60FAS is the optimal for correction of speed macroparameters of contraction for ischemic muscle damage. At the same time, intramuscular administration of C60FAS shows pronounced protective effect in movements associated with the generation of maximum force responses or prolonged contractions, which increase the muscle fatigue level...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28227973/improving-odorant-chemical-class-prediction-with-multi-layer-perceptrons-using-temporal-odorant-spike-responses-from-drosophila-melanogaster-olfactory-receptor-neurons
#2
Luqman R Bachtiar, Richard D Newcomb, Andrew V Kralicek, Charles P Unsworth, Luqman R Bachtiar, Richard D Newcomb, Andrew V Kralicek, Charles P Unsworth, Charles P Unsworth, Andrew V Kralicek, Richard D Newcomb, Luqman R Bachtiar
In this work, we examine the possibility of improving the prediction performance of an olfactory biosensor through the use of temporal spiking data. We present an Artificial Neural Network (ANN), in the form of an optimal hybrid Multi-Layer Perceptron (MLP) system for the classification of chemical odorants from olfactory receptor neuron spike responses of the Drosophila melanogaster fruit fly (DmOrs). The data used in this study contains the responses to 34 odorants from 6 individual DmOrs, of which we exploit the temporal spiking responses of a 500ms odorant stimulus window...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227942/unified-phase-variables-of-relative-degree-two-for-human-locomotion
#3
Dario J Villarreal, Robert D Gregg, Dario J Villarreal, Robert D Gregg, Robert D Gregg, Dario J Villarreal
A starting point to achieve stable locomotion is synchronizing the leg joint kinematics during the gait cycle. Some biped robots parameterize a nonlinear controller (e.g., input-output feedback linearization) whose main objective is to track specific kinematic trajectories as a function of a single mechanical variable (i.e., a phase variable) in order to allow the robot to walk. A phase variable capable of parameterizing the entire gait cycle, the hip phase angle, has been used to control wearable robots and was recently shown to provide a robust representation of the phase of human gait...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227938/integrated-rf-shim-coil-allowing-two-degrees-of-freedom-shim-current
#4
Jiazheng Zhou, Ying-Hua Chu, Yi-Cheng Hsu, Pu-Yeh Wu, Jason P Stockmann, Fa-Hsuan Lin, Jiazheng Zhou, Ying-Hua Chu, Yi-Cheng Hsu, Pu-Yeh Wu, Jason P Stockmann, Fa-Hsuan Lin, Pu-Yeh Wu, Jason P Stockmann, Fa-Hsuan Lin, Jiazheng Zhou, Ying-Hua Chu, Yi-Cheng Hsu
High-quality magnetic resonance imaging and spectroscopic measurements require a highly homogeneous magnetic field. Different from global shimming, localized off-resonance can be corrected by using multi-coil shimming. Previously, integrated RF and shimming coils have been used to implement multi-coil shimming. Such coils share the same conductor for RF signal reception and shim field generation. Here we propose a new design of the integrated RF-shim coil at 3-tesla, where two independent shim current paths are allowed in each coil...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227800/a-fresh-perspective-on-dissecting-action-into-discrete-submotions
#5
Justin Horowitz, Yazan Abdel Majeed, James Patton, Justin Horowitz, Yazan Abdel Majeed, James Patton, Justin Horowitz, Yazan Abdel Majeed, James Patton
The hypothesis that reaching motions are constructed from discrete components has been explored since the earliest scientific investigations of human movement, although composition specifics have been contentious. We reinspect this process by analyzing the underlying motor intent (rather than actual motion) using our recently-developed intent determination technique. First, synthetic data analysis was used to determine our accuracy in detecting submotion events. Next, we evaluated this on healthy reaching movements and overcame the problem of indistinguishably blended submotions by exposing subjects to strong, abruptly changing forces, which lead to clear corrections identifiable using direction-based clustering...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227771/tracking-intrinsic-connectivity-brain-network-features-during-successive-pseudo-resting-states-and-interoceptive-task-fmri
#6
Behnaz Jarrahi, Dante Mantini, Behnaz Jarrahi, Dante Mantini, Behnaz Jarrahi, Dante Mantini
Advanced multivariate analyses of functional magnetic resonance imaging (fMRI) data based on blood oxygen level-dependent (BOLD) contras have revealed that the human brain organizes its activities into multiple intrinsic connectivity networks (ICNs). Several fMRI studies have evaluated the modulations of these networks during different cognitive or emotional tasks using blind source separation techniques particularly the independent component analysis (ICA). In this exploratory study, we applied ICA methodology to examine ICN modulations under different interoceptive conditions...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227769/identifying-the-effects-of-visceral-interoception-on-human-brain-connectome-a-multivariate-analysis-of-covariance-of-fmri-data
#7
Behnaz Jarrahi, Dante Mantini, Behnaz Jarrahi, Dante Mantini, Behnaz Jarrahi, Dante Mantini
Sources of variations in the neural circuitry of the human brain and interrelationship between intrinsic connectivity networks (ICNs) are still a matter of debate and ongoing research. Here, we applied a multivariate analysis of covariance (MANCOVA) based on high-dimensional independent component analysis (ICA) to identify the effects of interoception and related variables on human brain connectome. Fifteen healthy right-handed subjects (all females, age range 21 - 48 years; mean age = 30.3, SD = 8.7 years) underwent a blood-oxygen-level-dependent (BOLD) functional magnetic resonance imaging (fMRI) that included continuous intravesical saline infusion and drainage...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227767/regional-brain-activity-that-determines-successful-and-unsuccessful-working-memory-formation
#8
Shohei Teramoto, Tsubasa Inaoka, Yumie Ono, Shohei Teramoto, Tsubasa Inaoka, Yumie Ono, Shohei Teramoto, Tsubasa Inaoka, Yumie Ono
Using EEG source reconstruction with Multiple Sparse Priors (MSP), we investigated the regional brain activity that determines successful memory encoding in two participant groups of high and low accuracy rates. Eighteen healthy young adults performed a sequential fashion of visual Sternberg memory task. The 32-channel EEG was continuously measured during participants performed two 70 trials of memory task. The regional brain activity corresponding to the oscillatory EEG activity in the alpha band (8-13 Hz) during encoding period was analyzed by MSP implemented in SPM8...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227761/application-of-dti-connectivity-in-lateralization-of-mtle
#9
Mohammad R Nazem-Zadeh, Susan M Bowyer, John E Moran, Esmaeil Davoodi-Bojd, Andrew Zillgitt, Hassan Bagher-Ebadian, Fariborz Mahmoudi, Kost V Elisevich, Hamid Soltanian-Zadeh, Mohammad R Nazem-Zadeh, Susan M Bowyer, John E Moran, Esmaeil Davoodi-Bojd, Andrew Zillgitt, Hassan Bagher-Ebadian, Fariborz Mahmoudi, Kost V Elisevich, Hamid Soltanian-Zadeh, Susan M Bowyer, Hassan Bagher-Ebadian, Esmaeil Davoodi-Bojd, Andrew Zillgitt, Fariborz Mahmoudi, John E Moran, Hamid Soltanian-Zadeh, Kost V Elisevich, Mohammad R Nazem-Zadeh
Diffusion tensor imaging (DTI) is a noninvasive imaging method for measuring the diffusion properties of the underlying white matter tracts through which epileptiform activity is propagated. This study investigates the structural abnormalities quantified by DTI in mesial temporal lobe epilepsy (mTLE). Fiber tracts passing through 54 anatomical sites in 12 adult mTLE patients and 12 age- and gender-matched controls were identified using DTI tractography. DTI nodal degree (ND) and laterality index were then calculated...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227729/high-frame-rate-medical-quality-video-compression-for-tele-eeg
#10
Laurent Lambert, Syed Zahid Ahmed, Khalil Hachicha, Andrea Pinna, Patrick Garda, Laurent Lambert, Syed Zahid Ahmed, Khalil Hachicha, Andrea Pinna, Patrick Garda, Syed Zahid Ahmed, Andrea Pinna, Laurent Lambert, Patrick Garda, Khalil Hachicha
More and more, exams require medical images as a tool to diagnose pathologies. Thus, the transfer and storage of the exam data becomes a critical issue. To address this issue, an image compression algorithm called Waaves has been developed and certified for medical imaging. Our work in this paper deals with a scenario of EEG exams where video of the patient is also recorded in order to correctly diagnose myoclonus pathologies. To achieve this goal, the video needs to be of high quality and at frame rate of at least 100 frames per second...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227707/estimation-of-muscle-fatigue-by-ratio-of-mean-frequency-to-average-rectified-value-from-surface-electromyography
#11
Jeffry Bonar Fernando, Mototaka Yoshioka, Jun Ozawa, Jeffry Bonar Fernando, Mototaka Yoshioka, Jun Ozawa, Mototaka Yoshioka, Jeffry Bonar Fernando, Jun Ozawa
A new method to estimate muscle fatigue quantitatively from surface electromyography (EMG) is proposed. The ratio of mean frequency (MNF) to average rectified value (ARV) is used as the index of muscle fatigue, and muscle fatigue is detected when MNF/ARV falls below a pre-determined or pre-calculated baseline. MNF/ARV gives larger distinction between fatigued muscle and non-fatigued muscle. Experiment results show the effectiveness of our method in estimating muscle fatigue more correctly compared to conventional methods...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227702/socioeconomic-status-age-and-heart-rate-variability-in-a-bangladeshi-community
#12
Nishat E-Sharmin Trisha, Herbert F Jelinek, Mika P Tarvainen, David J Cornforth, Dewan S Alam, Megan Smith, Nishat E-Sharmin Trisha, Herbert F Jelinek, Mika P Tarvainen, David J Cornforth, Dewan S Alam, Megan Smith, Herbert F Jelinek, David J Cornforth, Megan Smith, Nishat E-Sharmin Trisha, Dewan S Alam, Mika P Tarvainen
Socioeconomic status (SES) is a risk factor for cardiovascular disease (CVD) and either low or high heart rate variability (HRV) at rest has been shown to predict cardiovascular morbidity and mortality. The study investigated the extent HRV features can predict SES. Four hundred and twenty eight people were randomly selected from the commercial districts (high SES) and slum areas (low SES) within Dhaka city. Demographic, clinical, and HRV features were recorded. Of the clinical variables age, waist circumference and diastolic blood pressure (p<;0...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227698/predicting-brain-stimulation-treatment-outcomes-of-depressed-patients-through-the-classification-of-eeg-oscillations
#13
Alaa M Al-Kaysi, Ahmed Al-Ani, Colleen K Loo, Michael Breakspear, Tjeerd W Boonstra, Alaa M Al-Kaysi, Ahmed Al-Ani, Colleen K Loo, Michael Breakspear, Tjeerd W Boonstra, Michael Breakspear, Ahmed Al-Ani, Tjeerd W Boonstra, Colleen K Loo
Major depressive disorder (MDD) is a mental disorder that is characterized by negative thoughts, mood and behavior. Transcranial direct current stimulation (tDCS) has recently emerged as a promising brain-stimulation treatment for MDD. A standard tDCS treatment involves numerous sessions that run over a few weeks, however, not all participants respond to this type of treatment. This study aims to predict which patients improve in mood and cognition in response to tDCS treatment by analyzing electroencephalography (EEG) of MDD patients that was collected at the start of tDCS treatment...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227670/diffuse-reflectance-spectroscopy-can-differentiate-high-grade-and-low-grade-prostatic-carcinoma
#14
Priya N Werahera, Edward A Jasion, E David Crawford, M Scott Lucia, Adrie van Bokhoven, Holly T Sullivan, Fernando J Kim, Paul D Maroni, J David Port, John W Daily, Francisco G La Rosa, Priya N Werahera, Edward A Jasion, E David Crawford, M Scott Lucia, Adrie van Bokhoven, Holly T Sullivan, Fernando J Kim, Paul D Maroni, J David Port, John W Daily, Francisco G La Rosa, John W Daily, Adrie Van Bokhoven, E David Crawford, J David Port, Priya N Werahera, M Scott Lucia, Holly T Sullivan, Paul D Maroni, Edward A Jasion, Francisco G La Rosa, Fernando J Kim
Prostate tumors are graded by the revised Gleason Score (GS) which is the sum of the two predominant Gleason grades present ranging from 6-10. GS 6 cancer exclusively with Gleason grade 3 is designated as low grade (LG) and correlates with better clinical prognosis for patients. GS >7 cancer with at least one of the Gleason grades 4 and 5 is designated as HG indicate worse prognosis for patients. Current transrectal ultrasound guided prostate biopsies often fail to correctly diagnose HG prostate cancer due to sampling errors...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227636/a-system-to-monitor-tremors-in-patients-with-parkinson-s-disease
#15
A Bermeo, M Bravo, M Huerta, A Soto, A Bermeo, M Bravo, M Huerta, A Soto, A Bermeo, M Huerta, A Soto, M Bravo
In this work the design and development of a system to monitor tremors in patients with Parkinson's disease based on Arduino open-source prototyping platform is presented. For processing data tremors acquired by the sensor device we have developed an Android application which allows an evaluation of the state of PD patients based on three types of tests that are in the Unified Parkinson's Disease Rating Scale recommended by the Movement Disorder Society (MDS-UPDRS); the tests performed in the application are: postural tremor of the hands, kinetic tremors of the hands and resting tremor amplitude...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227610/unraveling-fabrication-and-calibration-of-wearable-gas-monitor-for-use-under-free-living-conditions
#16
Yue Deng, Cheng Chen, Francis Tsow, Xiaojun Xian, Erica Forzani, Yue Deng, Cheng Chen, Francis Tsow, Xiaojun Xian, Erica Forzani, Yue Deng, Xiaojun Xian, Erica Forzani, Cheng Chen, Francis Tsow
Volatile organic compounds (VOC) are organic chemicals that have high vapor pressure at regular conditions. Some VOC could be dangerous to human health, therefore it is important to determine real-time indoor and outdoor personal exposures to VOC. To achieve this goal, our group has developed a wearable gas monitor with a complete sensor fabrication and calibration protocol for free-living conditions. Correction factors for calibrating the sensors, including sensitivity, aging effect, and temperature effect are implemented into a Quick Response Code (QR code), so that the pre-calibrated quartz tuning fork (QTF) sensor can be used with the wearable monitor under free-living conditions...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227606/video-analysis-validation-of-a-real-time-physical-activity-detection-algorithm-based-on-a-single-waist-mounted-tri-axial-accelerometer-sensor
#17
Alan K Bourke, Espen A F Ihlen, Pepijn Van de Ven, John Nelson, Jorunn L Helbostad, Alan K Bourke, Espen A F Ihlen, Pepijn Van de Ven, John Nelson, Jorunn L Helbostad, Jorunn L Helbostad, Alan K Bourke, John Nelson, Pepijn Van de Ven, Espen Af Ihlen
We have validated a real-time activity classification algorithm based on monitoring by a body worn system which is potentially suitable for low-power applications on a relatively computationally lightweight processing unit. The algorithm output was validated using annotation data generated from video recordings of 20 elderly volunteers performing both a semi-structured protocol and a free-living protocol. The algorithm correctly identified sitting 75.1% of the time, standing 68.8% of the time, lying 50.9% of the time, and walking and other upright locomotion 82...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227565/a-simulation-analysis-of-the-variability-of-the-roving-level-hearing-test
#18
Greg D Watkins, Brett A Swanson, Gregg J Suaning, Greg D Watkins, Brett A Swanson, Gregg J Suaning, Greg D Watkins, Brett A Swanson, Gregg J Suaning
In the study of auditory prostheses, the Speech Recognition Threshold (SRT) is the Signal to Noise Ratio (SNR) at which 50% of words are correctly identified. SRT is typically measured using an adaptive procedure wherein speech is presented at a fixed sound pressure level (SPL) and the noise level is varied according to the subject's responses. A roving level SRT test has been used by researchers with the goal of including the effectiveness of Automatic Gain Control (AGC) systems in SRT measurements. The roving method presents speech at three different SPLs with the level for each sentence chosen pseudo-randomly, while adaptively varying the SNR...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227539/robot-assisted-assessment-of-wrist-proprioception-does-wrist-proprioceptive-acuity-follow-weber-s-law
#19
Sara Contu, Francesca Marini, Leonardo Cappello, Lorenzo Masia, Sara Contu, Francesca Marini, Leonardo Cappello, Lorenzo Masia, Lorenzo Masia, Sara Contu, Leonardo Cappello, Francesca Marini
Proprioception is essential for planning and controlling limb posture and movement. In our recent work, we introduced a standardized robot-aided method for measuring proprioceptive discrimination thresholds at the wrist to obtain reliable and accurate measures of proprioceptive acuity. Weber's law defines discrimination thresholds as a constant ratio between the just noticeable difference and the reference or standard stimulus. Reporting Weber's fractions thus provides the possibility of comparing results with the reports of others collected worldwide...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227537/assessing-the-contribution-of-the-individual-alpha-frequency-iaf-in-an-eeg-based-study-of-program-comprehension
#20
Igor Crk, Timothy Kluthe, Igor Crk, Timothy Kluthe, Timothy Kluthe, Igor Crk
Empirical studies of programming language learnability and usability have thus far depended on indirect measures of human cognitive performance, attempting to capture what is at its essence a purely cognitive exercise through various indicators of comprehension, such as the time spent working out the meaning of code and producing acceptable solutions. We present evidence of the relative contribution of experience and the individual alpha frequency (IAF) to achieving correct performance during program comprehension tasks, specifically that more experience and higher IAF are both associated with an increased likelihood of correct task performance, with experience playing the greater part...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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