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https://www.readbyqxmd.com/read/28434160/repeated-mild-traumatic-brain-injuries-is-not-associated-with-volumetric-differences-in-former-high-school-football-players
#1
Douglas P Terry, L Stephen Miller
We investigated potential brain volumetric differences in a sample of former high school football players many years after these injuries. Forty community-dwelling males ages 40-65 who played high school football, but not college or professional sports, were recruited. The experimental group (n = 20) endorsed experiencing two or more mTBIs on an empirically validated mTBI assessment tool (median = 3, range = 2-15). The control group (n = 20) denied ever experiencing an mTBI. Participants completed a self-report index of current mTBI symptomatology and underwent high-resolution T1-weighted MRI scanning, which were analyzed using the Freesurfer software package...
April 22, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28434075/associations-of-self-reported-smoking-cotinine-levels-and-epigenetic-smoking-indicators-with-oxidative-stress-among-older-adults-a-population-based-study
#2
Xu Gao, Xīn Gào, Yan Zhang, Lutz Philipp Breitling, Ben Schöttker, Hermann Brenner
Tobacco smoking and oxidative stress (OS) are both related to a wide spectrum of adverse age-related health outcomes, but their association is not yet well-established. We examined the associations of self-reported smoking indicators, serum cotinine levels and smoking-related DNA methylation biomarkers with two urinary proxy markers of OS, 8-isoprostane (8-iso) and 8-hydroxy-2'-deoxyguanosine (8-oxodG), in two independent subsets of older adults recruited in Germany (discovery set: n = 978, validation set: n = 531)...
April 22, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28434023/developing-a-statistically-powerful-measure-for-quartet-tree-inference-using-phylogenetic-identities-and-markov-invariants
#3
Jeremy G Sumner, Amelia Taylor, Barbara R Holland, Peter D Jarvis
Recently there has been renewed interest in phylogenetic inference methods based on phylogenetic invariants, alongside the related Markov invariants. Broadly speaking, both these approaches give rise to polynomial functions of sequence site patterns that, in expectation value, either vanish for particular evolutionary trees (in the case of phylogenetic invariants) or have well understood transformation properties (in the case of Markov invariants). While both approaches have been valued for their intrinsic mathematical interest, it is not clear how they relate to each other, and to what extent they can be used as practical tools for inference of phylogenetic trees...
April 22, 2017: Journal of Mathematical Biology
https://www.readbyqxmd.com/read/28434022/effects-of-vestibular-disorders-on-vestibular-reflex-and-imagery
#4
B S Cohen, J Provasi, P Leboucher, I Israël
The aim of this study was to establish the effect of vestibular lesion on vestibular imagery. Subjects were required to estimate verbally their passively travelled rotation angles in complete darkness, i.e., to activate vestibular imagery. During motion, the vestibulo-ocular reflex (VOR) was measured. Thus, we examined the coherence between the vestibulo-ocular reflex and self-rotation imagery, with vestibular-lesioned patients and healthy participants. Unilateral acute and chronic patients, bilateral patients, and healthy subjects were compared...
April 22, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28434011/management-of-coxa-vara-septica-and-pseudoarthrosis-of-the-femoral-neck-a-case-report
#5
Hasime Qorraj Bytyqi, Cen Bytyqi
BACKGROUND Coxa vara and pseudoarthrosis of the femoral neck after septic hip arthritis is a very rare disease. The aim of this study was to present a case with pseudoarthrosis of the femoral neck, with coxa vara after neonatal septic arthritis of the right hip, and treatment of the pseudarthrosis with proximal femoral valgus osteotomy. CASE REPORT A 12-month-old female, who had suffered neonatal septic arthritis with a five-day history of fever and painful right hip now demonstrated painless limping to the right hip, pelvic obliquity, Trendelenburg-Duchenne gait, limitation of hip abduction, lower-extremity length discrepancy with 3...
April 23, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28433885/electric-fields-within-clay-materials-how-to-affect-the-adsorption-of-metal-ions
#6
Xiong Li, Hang Li, Gang Yang
Electric fields exist ubiquitously in chemical and biological systems while how to affect the interfacial adsorption processes remain elusive. Here, molecular dynamics simulations are used to understand at a molecular level the adsorption of metal ions at the interface of aqueous solutions and clay materials that are generally endowed with strong electric fields. In absence of electric fields, even Cs(+), one of the strongest adsorbed metal ions, is facile to detach from solvated clay surfaces. Electric fields are critical to construct stable inner-sphere complexes and enhance pronouncedly the adsorption strengths of both inner- and outer-sphere complexes...
April 13, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28433871/automatic-cumulative-sums-contour-detection-of-fbp-reconstructed-multi-object-nuclear-medicine-images
#7
Nicholas E Protonotarios, George M Spyrou, George A Kastis
The problem of determining the contours of objects in nuclear medicine images has been studied extensively in the past, however most of the analysis has focused on a single object as opposed to multiple objects. The aim of this work is to develop an automated method for determining the contour of multiple objects in positron emission tomography (PET) and single photon emission computed tomography (SPECT) filtered backprojection (FBP) reconstructed images. These contours can be used for computing body edges for attenuation correction in PET and SPECT, as well as for eliminating streak artifacts outside the objects, which could be useful in compressive sensing reconstruction...
April 14, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28433848/instrumented-circumferential-fusion-in-two-stages-for-instable-lumbar-fracture-long-term-results-of-a-series-of-74-patients-on-sagittal-balance-and-functional-outcomes
#8
Mourad Ould-Slimane, Camille Damade, Guillaume Lonjon, André Gilibert, Jérôme Cochereau, Rémi Gauthé, Nicolas Lonjon
AIM: To report the radiological and functional results of a multicentre, prospective case series of patients with comminuted lumbar fractures treated with two-stage circumferential arthrodesis. METHODS: A multicentre, prospective case series of 74 patients with comminuted lumbar fractures was analyzed. The strategy entailed initial posterior osteosynthesis then physical replacement with an expandable titanium cage filled with autologous bone, via retroperitoneal lumbotomy...
April 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28433821/developmental-change-in-children-s-sensitivity-to-sound-symbolism
#9
Christina Y Tzeng, Lynne C Nygaard, Laura L Namy
The current study examined developmental change in children's sensitivity to sound symbolism. Three-, five-, and seven-year-old children heard sound symbolic novel words and foreign words meaning round and pointy and chose which of two pictures (one round and one pointy) best corresponded to each word they heard. Task performance varied as a function of both word type and age group such that accuracy was greater for novel words than for foreign words, and task performance increased with age for both word types...
April 20, 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/28433817/climate-change-risks-extinction-debt-and-conservation-implications-for-a-threatened-freshwater-fish-carmine-shiner-notropis-percobromus
#10
Shubha N Pandit, Bryan M Maitland, Laxmi K Pandit, Mark S Poesch, Eva C Enders
Climate change is affecting many freshwater species, particularly fishes. Predictions of future climate change suggest large and deleterious effects on species with narrow dispersal abilities due to limited hydrological connectivity. In turn, this creates the potential for population isolation in thermally unsuitable habitats, leading to physiological stress, species declines or possible extirpation. The current extent of many freshwater fish species' spatio-temporal distribution patterns and their sensitivity to thermal impacts from climate change - critical information for conservation planning - are often unknown...
April 20, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28433753/computational-image-analysis-for-prognosis-determination-in-dme
#11
Bianca S Gerendas, Hrvoje Bogunovic, Amir Sadeghipour, Thomas Schlegl, Georg Langs, Sebastian M Waldstein, Ursula Schmidt-Erfurth
In this pilot study, we evaluated the potential of computational image analysis of optical coherence tomography (OCT) data to determine the prognosis of patients with diabetic macular edema (DME). Spectral-domain OCT scans with fully automated retinal layer segmentation and segmentation of intraretinal cystoid fluid (IRC) and subretinal fluid of 629 patients receiving anti-vascular endothelial growth factor therapy for DME in a randomized prospective clinical trial were analyzed. The results were used to define 312 potentially predictive features at three timepoints (baseline, weeks 12 and 24) for best-corrected visual acuity (BCVA) at baseline and after one year used in a random forest prediction path...
April 19, 2017: Vision Research
https://www.readbyqxmd.com/read/28433703/corrections
#12
(no author information available yet)
No abstract text is available yet for this article.
April 19, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28433624/temporal-slice-registration-and-robust-diffusion-tensor-reconstruction-for-improved-fetal-brain-structural-connectivity-analysis
#13
Bahram Marami, Seyed Sadegh Mohseni Salehi, Onur Afacan, Benoit Scherrer, Caitlin K Rollins, Edward Yang, Judy A Estroff, Simon K Warfield, Ali Gholipour
Diffusion weighted magnetic resonance imaging, or DWI, is one of the most promising tools for the analysis of neural microstructure and the structural connectome of the human brain. The application of DWI to map early development of the human connectome in-utero, however, is challenged by intermittent fetal and maternal motion that disrupts the spatial correspondence of data acquired in the relatively long DWI acquisitions. Fetuses move continuously during DWI scans. Reliable and accurate analysis of the fetal brain structural connectome requires careful compensation of motion effects and robust reconstruction to avoid introducing bias based on the degree of fetal motion...
April 19, 2017: NeuroImage
https://www.readbyqxmd.com/read/28433623/combined-fmri-mrs-acquires-simultaneous-glutamate-and-bold-fmri-signals-in-the-human-brain
#14
I Betina Ip, Adam Berrington, Aaron T Hess, Andrew J Parker, Uzay E Emir, Holly Bridge
Combined fMRI-MRS is a novel method to non-invasively investigate functional activation in the human brain using simultaneous acquisition of hemodynamic and neurochemical measures. The aim of the current study was to quantify neural activity using combined fMRI-MRS at 7 T. BOLD-fMRI and semi-LASER localization MRS data were acquired from the visual cortex of 13 participants during short blocks (64s) of flickering checkerboards. We demonstrate a correlation between glutamate and BOLD-fMRI time courses (R = 0...
April 18, 2017: NeuroImage
https://www.readbyqxmd.com/read/28433536/assessment-of-enamel-cracks-at-adhesive-cavosurface-margin-using-three-dimensional-swept-source-optical-coherence-tomography
#15
Tomoko Tabata, Yasushi Shimada, Alireza Sadr, Junji Tagami, Yasunori Sumi
OBJECTIVES: Swept-source optical coherence tomography (SS-OCT) can construct cross-sectional images of internal biological structures. The aim of this study was to evaluate enamel cracks at the cavosurface margin of composite restorations using SS-OCT. METHODS: Bowl-shaped cavities were prepared at two locations (mid-coronal and cervical regions) on the enamel surface of 60 bovine teeth. Half of the cavities (30) were treated with phosphoric acid gel. A two-step self-etch adhesive (Clearfil SE Bond) was applied to all cavities and a flowable composite was placed in bulk...
April 19, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28433482/variations-of-target-volume-definition-and-daily-target-volume-localization-in-stereotactic-body-radiotherapy-for-early-stage-non-small-cell-lung-cancer-patients-under-abdominal-compression
#16
Chunhui Han, Sagus Sampath, Timothy E Schultheisss, Jeffrey Y C Wong
We aimed to compare gross tumor volumes (GTV) in 3-dimensional computed tomography (3DCT) simulation and daily cone beam CT (CBCT) with the internal target volume (ITV) in 4-dimensional CT (4DCT) simulation in stereotactic body radiotherapy (SBRT) treatment of patients with early-stage non-small cell lung cancer (NSCLC) under abdominal compression. We retrospectively selected 10 patients with NSCLC who received image-guided SBRT treatments under abdominal compression with daily CBCT imaging. GTVs were contoured as visible gross tumor on the planning 3DCT and daily CBCT, and ITVs were contoured using maximum intensity projection (MIP) images of the planning 4DCT...
April 19, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28433473/sex-difference-in-the-heat-shock-response-to-high-external-load-resistance-training-in-older-humans
#17
Rose Njemini, Louis Nuvagah Forti, Tony Mets, Evelien Van Roie, Walter Coudyzer, Ingo Beyer, Christophe Delecluse, Ivan Bautmans
BACKGROUND: Literature reports on the effects of resistance training on heat shock protein70 (Hsp70) adaptation in older subjects are scarce. Moreover, the optimum training load required to obtain a beneficial adaptation profile is lacking. Therefore, the aim of this study was to determine the effects of resistance training at various external loads on extracellular Hsp70 (eHsp70) resting levels in older humans. METHODS: Fifty-six community-dwelling older (68±5years) volunteers were randomized to 12weeks of resistance training (3×/week) at either high-resistance (HIGH, 8 males, 10 females, 2×10-15 repetitions at 80%1RM), low resistance (LOW, 9 Males, 10 Females, 1×80-100 repetitions at 20%1RM), or mixed low resistance (LOW+, 9 Males, 10 Females, 1×60 repetitions at 20%1RM followed by 1×10-20 repetitions at 40%1RM)...
April 19, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28433450/a-retrospective-cohort-study-of-concomitant-ipsilateral-extra-capsular-and-intra-capsular-fractures-of-the-proximal-femur-are-they-casual-findings-or-an-undervalued-reality
#18
Miquel Videla-Cés, José-Miguel Sales-Pérez, Joan Girós-Torres, Rubén Sánchez-Navés, Sebastián Videla
BACKGROUND: Fractures of the proximal femur constitute a major public health problem, with an annual incidence in Spain of 7.6 cases per 1000 inhabitants over 65 years of age. Hip fractures are frequent in elderly patients, related to osteoporosis and with low energy trauma, which means that they can be considered a geriatric syndrome. Simultaneous ipsilateral extra- and intra-articular hip fractures are considered as very rare are, and generally speaking, classified as extra- or intra-capsular fractures...
April 13, 2017: Injury
https://www.readbyqxmd.com/read/28433442/strabismus-and-mental-disorders-among-israeli-adolescents
#19
Ilan Merdler, Moshe Giladi, Nir Sorkin, Shachar Shapira, Eran Galili, Alexander Margulis, Tzfanya Korach, Ayal Hassidim
PURPOSE: To assess the association between strabismus and mental disorders in adolescents. METHODS: This case-control study included 662,641 Israeli teenagers that underwent medical evaluation by the Israel Defense Force as part of the preconscription assessment between 2005 and 2013. The association between common mental disorders (anxiety disorder, mood disorder, adjustment disorder, and attention deficit hyperactivity disorder [ADHD]) and either uncorrected strabismus or corrected strabismus was examined...
April 19, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28433432/ascende-rt-an-analysis-of-treatment-related-morbidity-for-a-randomized-trial-comparing-a-low-dose-rate-brachytherapy-boost-with-a-dose-escalated-external-beam-boost-for-high-and-intermediate-risk-prostate-cancer
#20
Sree Rodda, Scott Tyldesley, W James Morris, Mira Keyes, Ross Halperin, Howard Pai, Michael McKenzie, Graeme Duncan, Gerard Morton, Jeremy Hamm, Nevin Murray
PURPOSE: To report the genitourinary (GU) and gastrointestinal (GI) morbidity and erectile dysfunction in a randomized trial comparing 2 methods of dose escalation for high- and intermediate-risk prostate cancer. METHODS AND MATERIALS: ASCENDE-RT (Androgen Suppression Combined with Elective Nodal and Dose Escalated Radiation Therapy) enrolled 398 men, median age 68 years, who were then randomized to either a standard arm that included 12 months of androgen deprivation therapy and pelvic irradiation to 46 Gy followed by a dose-escalated external beam radiation therapy (DE-EBRT) boost to 78 Gy, or an experimental arm that substituted a low-dose-rate prostate brachytherapy (LDR-PB) boost...
January 6, 2017: International Journal of Radiation Oncology, Biology, Physics
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