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https://www.readbyqxmd.com/read/29470690/early-introduction-of-complementary-foods-and-childhood-overweight-in-breastfed-and-formula-fed-infants-in-the-netherlands-the-piama-birth-cohort-study
#1
Linda P M Pluymen, Alet H Wijga, Ulrike Gehring, Gerard H Koppelman, Henriëtte A Smit, L van Rossem
PURPOSE: To investigate whether early introduction of complementary foods (CF) is associated with an increased risk of overweight during childhood, and whether this association differs between formula-fed and breastfed infants. METHODS: We included 2611 participants that were born at term from a Dutch population-based birth cohort (n = 3963) designed to investigate the development of asthma and allergies. Parents kept records of their infant's age when CF were first introduced...
February 22, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29470658/current-status-of-potential-therapies-for-ige-mediated-food-allergy
#2
REVIEW
Christopher P Parrish, Daniel Har, J Andrew Bird
PURPOSE OF REVIEW: The goal of this review is to provide the reader with an updated summary of published trial data regarding the use of oral immunotherapy (OIT), sublingual immunotherapy (SLIT), and epicutaneous immunotherapy (EPIT) for treatment of IgE-mediated food allergies. RECENT FINDINGS: Data from phase 2 trials for treatment of peanut allergy with OIT and EPIT reveal an increase in the threshold of reactivity for peanut-allergic children. Compared to EPIT, OIT promotes a greater increase in the threshold of reactivity; however, adverse events are more common with OIT...
February 22, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29467686/the-role-of-personality-in-daily-food-allergy-experiences
#3
Tamlin S Conner, Miranda Mirosa, Phil Bremer, Rana Peniamina
Food allergies present numerous challenges to coping in everyday life. Even simple things like planning a lunch with a friend can be stressful for people with food allergies. But are some people more adversely impacted by having a food allergy than other people? This paper addressed this question by investigating whether individual differences in the Big Five personality traits (neuroticism, extraversion, openness, agreeableness, and conscientiousness) are related to food allergy-related problems in everyday life among adults with food allergies...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29461207/evaluation-of-an-online-educational-program-for-parents-and-caregivers-of-children-with-food-allergies
#4
A Ruiz-Baqués, J Contreras-Porta, M Marques-Mejías, J M Cárdenas Rebollo, F Capel Torres, M N Ariño Pla, A Zorrozua Santisteban, T Chivato
BACKGROUND AND OBJECTIVE: The increasing prevalence of food allergy affects both patients and their families. Objective: The aim of this study was to evaluate the impact of an online educational program designed for parents and caregivers of children with food allergies. The program was developed by a multidisciplinary group comprising health care professionals, researchers, and expert patients under the participatory medicine model. MATERIAL AND METHODS: Participants took a 2-week online educational program covering major topics in food allergy management...
2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29461206/oral-immunotherapy-with-egg-and-milk-changes-in-peripheral-serum-cytokines-are-not-predictive-factors-for-severe-adverse-reactions-or-for-the-final-report
#5
E García-Lirio, C Gonzalez Diaz, A Gonzalez Hermosa, P Gamboa, R Aranguren, M L Sanz
BACKGROUND: Oral immunotherapy (OIT) is a new approach in patients with food allergy. Various immunological mechanisms underlie the reversal of food allergy. In this paper, we study possible changes in peripheral cytokine patterns during OIT. METHODS: Determinations of cytokines in peripheral blood were made in children who had milk or egg allergy and who received OIT. The determinations were made before and after OIT, and again following a final repeat oral challenge a month after a diet excluding the culprit food...
2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29459789/retrospective-observational-cohort-study-regarding-the-effect-of-breastfeeding-on-challenge-proven-food-allergy
#6
C D van Ginkel, G N van der Meulen, E Bak, B M J Flokstra-de Blok, B J Kollen, G H Koppelman, A E J Dubois
BACKGROUND/OBJECTIVES: Human breast milk is generally regarded as the best nutrition for infants in their first months of life. Whether breastfeeding has a protective effect on food allergy is a point of debate and the subject of this study. SUBJECTS/METHODS: This retrospective study was conducted in 649 children who underwent a double-blind placebo-controlled food challenge (DBPCFC) as part of routine care in a tertiary care clinic. Food allergy was defined as having at least one positive DBPCFC to any food...
February 19, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29459524/-the-clinical-characteristics-of-peanut-allergy-and-the-diagnostic-accuracy-of-the-specific-ige-to-ara-h-2
#7
Naofumi Hayashi, Tomoko Nakagawa, Teruaki Matsui, Shiro Sugiura, Naoyuki Kando, Komei Ito
BACKGROUND: This study aimed to evaluate the clinical accuracy of specific IgE (sIgE) to Ara h 2 in the diagnosis of peanut allergy (PA). We also investigated the prevalence of complications with other nut allergies in PA patients. METHODS: The Ara h 2-sIgE titer was examined in patients with positive results for sIgE to peanut from April 2014 to March 2015. The presence or absence of PA was diagnosed based on an oral food challenge or a convincing clinical history...
2018: Arerugī, [Allergy]
https://www.readbyqxmd.com/read/29459519/-food-allergy-and-anaphylaxis
#8
Katsushi Miura
No abstract text is available yet for this article.
2018: Arerugī, [Allergy]
https://www.readbyqxmd.com/read/29457221/association-of-stat6-gene-variants-with-food-allergy-diagnosed-by-double-blind-placebo-controlled-food-challenges
#9
C D van Ginkel, M E Pettersson, A E J Dubois, G H Koppelman
This study describes the role of two STAT6 gene variants in food allergy using data of patients and their parents who underwent double-blind placebo-controlled food challenges (DBPCFCs). After quality control, 369 trios were analyzed including 262 children (71.0%) with food allergy. Associations were tested by family based association testing (FBAT). The A alleles of both SNPs were associated with food allergy (p=0.036 and p=0.013 for rs324015 and rs1059513, respectively). Furthermore, these A alleles were associated with peanut allergy, higher sIgE levels to both peanut and cow's milk, more severe symptoms and higher eliciting doses during peanut and cow's milk DBPCFCs (all p<0...
February 19, 2018: Allergy
https://www.readbyqxmd.com/read/29456038/increase-of-natural-killer-cells-in-children-with-liver-transplantation-acquired-food-allergy
#10
F Mori, C Angelucci, A Cianferoni, S Barni, G Indolfi, A Casini, G Mangone, M Materassi, N Pucci, C Azzari, E Novembre
BACKGROUND: Transplantation-acquired food allergies (TAFA) are frequently reported and considered to be caused by immunosuppressive therapy. The aim of this study was to investigate the allergic and immunologic responses in children who had liver or kidney transplantations. METHODS: Twelve children receiving liver transplantations and 10 children receiving kidney transplantations were investigated. All children underwent the allergy work-up and in most of them, lymphocyte screening and serum cytokine measurements were also performed...
February 15, 2018: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/29455358/the-use-of-biomarkers-to-predict-aero-allergen-and-food-immunotherapy-responses
#11
REVIEW
Sayantani B Sindher, Andrew Long, Swati Acharya, Vanitha Sampath, Kari C Nadeau
The incidence of allergic conditions has continued to rise over the past several decades, with a growing body of research dedicated toward the treatment of such conditions. By driving a complex range of changes in the underlying immune response, immunotherapy is the only therapy that modulates the immune system with long-term effects and is presently utilized for the treatment of several atopic conditions. Recent efforts have focused on identifying biomarkers associated with these changes that may be of use in predicting patients with the highest likelihood of positive clinical outcomes during allergen immunotherapy (AIT), providing guidance regarding AIT discontinuation, and predicting symptomatic relapse and the need for booster AIT after therapy...
February 17, 2018: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/29454836/mechanism-for-initiation-of-food-allergy-dependence-on-skin-barrier-mutations-and-environmental-allergen-co-stimulation
#12
Matthew Walker, Jeremy Green, Ryan Ferrie, Ashley Queener, Mark H Kaplan, Joan M Cook-Mills
BACKGROUND: Mechanisms for the development of food allergy in neonates are unknown but are clearly linked in patient populations to a genetic predisposition towards skin barrier defects. Whether skin barrier defects functionally contribute to development of food allergy is unknown. OBJECTIVE: The purpose of the study was to determine whether skin barrier mutations, that are primarily heterozygous in patient populations, contribute to the development of food allergy...
February 15, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29454004/identification-and-analysis-of-peanut-specific-t-effector-and-t-regulatory-cells-in-children-allergic-and-tolerant-to-peanut
#13
Katherine A Weissler, Marjohn Rasooly, Tom DiMaggio, Hyejeong Bolan, Daly Cantave, David Martino, Melanie R Neeland, Mimi Lk Tang, Thanh D Dang, Katrina J Allen, Pamela A Frischmeyer-Guerrerio
BACKGROUND: Peanut allergy is potentially life-threatening and generally persists lifelong. Recent data suggests the skin may be an important route of initial sensitization to peanut, while early oral exposure to peanut is protective. In mice, T regulatory cells (Tregs) are central to development of tolerance to food, but their contribution to the pathogenesis of food allergy in humans is less clear. OBJECTIVE: We sought to quantify and phenotype peanut-specific CD4+ T effector (ps-Teff) and ps-Tregs in children with and without peanut allergy or sensitization...
February 14, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29448897/immunomodulation-by-food-impact-on-gut-immunity-and-immune-cell-function
#14
Satoshi Hachimura, Mamoru Totsuka, Akira Hosono
Recent studies have revealed that various food components affect the immune response. These components act on various immune cells, and their effects are mediated through the intestinal immune system and, in some cases, the intestinal microbiota. In this review, we describe the immunomodulating effects of various food components, including probiotics, prebiotics, polysaccharides, vitamins, minerals, fatty acids, peptides, amino acids and polyphenols. Some of these components enhance immune responses, leading to host defense against infection, whereas others inhibit immune responses, thus suppressing allergy and inflammation...
February 16, 2018: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/29446153/eating-fish-and-farm-life-reduce-allergic-rhinitis-at-the-age-of-twelve
#15
Styliana Vasileiadou, Göran Wennergren, Frida Strömberg Celind, Nils Åberg, Rolf Pettersson, Bernt Alm, Emma Goksör
BACKGROUND: The prevalence of allergic rhinitis has increased, but the cause of this rise is partly unknown. Our aim was to analyse the prevalence, risk factors and protective factors for allergic rhinitis in 12-year-old Swedish children. METHODS: Data were collected from a prospective, longitudinal cohort study of children born in western Sweden in 2003. The parents answered questionnaires when the children were six months to 12 years. The response rate at 12 years was 76% (3,637/4,777) of the questionnaires distributed...
February 15, 2018: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29439856/the-optimal-age-for-epicutaneous-sensitization-following-tape-stripping-in-balb-c-mice
#16
Masato Tamari, Keisuke Orimo, Kenichiro Motomura, Ken Arae, Akio Matsuda, Susumu Nakae, Hirohisa Saito, Hideaki Morita, Kenji Matsumoto
BACKGROUND: Direct contact of food proteins with eczematous lesions is thought to be the main cause of epicutaneous sensitization. To further investigate the development and pathogenesis of food allergy in vivo, a good mouse model of epicutaneous sensitization is needed. However, a fundamental problem in that regard is that the optimal age for epicutaneous sensitization of mice is unknown. In this study, we attempted to elucidate that optimal age. METHODS: Dorsal skin of wild-type BALB/c female mice (1, 3, 8 and 24 weeks old) was shaved, depilated and tape-stripped...
February 10, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29438186/peanut-allergy-reduction-in-high-risk-pediatric-patients
#17
Jaime Hopper, Courtney Hopp, Jessica Durbin
The prevalence of food allergies has doubled in the past 10 years. Peanut allergies are a significant public health issue and are the primary reason for food-related anaphylactic reactions that result in death. Evidence supports that early introduction of the peanut protein (or in combination with immunotherapy) to the highly allergic may safely desensitize patients, which could lead to less adverse allergic reactions and alter allergy management overall.
March 12, 2018: Nurse Practitioner
https://www.readbyqxmd.com/read/29434644/self-reported-questionnaire-survey-on-the-prevalence-and-symptoms-of-adverse-food-reactions-in-patients-with-chronic-inhalant-diseases-in-tangshan-city-china
#18
Guodong Hao, Xuxin Lai, Zhijing Song, Zhixing Wang, Xing-Ai Kong, Haifeng Zhong, Sui Fu Hui, Yiwu Zheng
Background: The prevalence of adverse food reactions in patients with chronic inhalant diseases has seldom been studied in China. This study is to investigate the prevalence of adverse food reactions and the symptoms caused in respiratory patients. Methods: Respiratory patients in allergy clinics were asked to complete a questionnaire. Patients' information such as age, gender, family history of allergy, and adverse reactions to a list of 48 foods and the symptoms caused, was recorded...
2018: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/29434319/maternal-vegetable-intake-in-early-pregnancy-and-wheeze-in-offspring-at-the-age-of-2-years
#19
Kohei Ogawa, Naho Morisaki, Minatsu Kobayashi, Seung Chik Jwa, Yukako Tani, Haruhiko Sago, Reiko Horikawa, Takeo Fujiwara
BACKGROUND/OBJECTIVES: Vegetable intake during childhood may reduce the risk of subsequent asthma. We verified the effect of maternal intake during pregnancy on asthma risk in offspring, which has rarely been studied. SUBJECTS/METHODS: In a hospital-based birth cohort study conducted in Tokyo, we administered a food frequency questionnaire at two periods during the respondents' pregnancy: early and mid to late periods. In addition, a questionnaire including the International Study of Asthma and Allergies in Childhood questionnaire was conducted when the offspring were 2 years old...
February 12, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29433792/clinical-characteristics-of-influenza-virus-induced-lower-respiratory-infection-during-the-2015-to-2016-season
#20
Kazuhiro Uda, Kensuke Shoji, Chitose Koyama-Wakai, Munehiro Furuichi, Noriyasu Iwase, Seiichiro Fujisaki, Shinji Watanabe, Isao Miyairi
BACKGROUND: Influenza A(H1N1)pdm09 virus infections often manifest severe respiratory symptoms, particularly in patients with a past history of allergic disease. Most of these findings were reported during the 2009 pandemic. The purpose of this study was to detail the clinical characteristics of influenza virus-induced lower respiratory infection (LRI) during the A(H1N1)pdm09-predominant 2015-2016 season. METHODS: We retrospectively reviewed the clinical characteristics of influenza-induced LRI cases in children admitted to a tertiary children's hospital...
February 9, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
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