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https://www.readbyqxmd.com/read/29220107/eating-out-with-a-food-allergy-in-the-uk-change-in-the-eating-out-practices-of-consumers-with-food-allergy-following-introduction-of-allergen-information-legislation
#1
Fiona M Begen, Julie Barnett, Ros Payne, Hazel M Gowland, Audrey DunnGalvin, Jane S Lucas
BACKGROUND: Strict allergen avoidance is important in day-to-day management of food allergy and avoidance when eating outside the home can present particular difficulties. EU legislation (EU FIC) introduced in December 2014 aimed to improve food allergen information provision for customers by requiring retailers of non-prepacked foods to provide information related to the content of one or more of 14 specified food allergens within their foods. OBJECTIVES: To investigate the impact of EU FIC on the behaviours, experiences and attitudes of consumers with food allergy when eating out...
December 8, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29218832/necrotizing-enterocolitis-in-the-setting-of-milk-allergy-after-pediatric-living-donor-liver-transplantation
#2
Soichi Narumoto, Seisuke Sakamoto, Hajime Uchida, Kengo Sasaki, Takanobu Shigeta, Akinari Fukuda, Shunsuke Nosaka, Rie Irie, Takako Yoshioka, Mureo Kasahara
NEC is an idiopathic intestinal mucosal injury that may progress to transmural bowel necrosis without mesenteric ischemia. NEC usually affects 7- to 10-day-old neonates following enteral feeding. A 10-month-old girl with no history of laparotomy underwent LDLT for acute liver failure. After starting enteral feeding on postoperative day 5, she developed abdominal distention. Diffuse PVG and PI were detected by radiologic modalities. Exploratory laparotomy revealed patchy necrosis of the intestine without perforation...
December 7, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/29215592/natural-korean-medicine-dang-gui-biosynthesis-effective-extraction-and-formulations-of-major-active-pyranocoumarins-their-molecular-action-mechanism-in-cancer-and-other-biological-activities
#3
REVIEW
Chinreddy Subramanyam Reddy, Seong Cheol Kim, Mok Hur, Yeon Bok Kim, Chun Geon Park, Woo Moon Lee, Jae Ki Jang, Sung Cheol Koo
Angelica gigas Nakai (AGN) is a crucial oriental medicinal herb that grows especially in Korea and the Far-East countries. It contains chemically active compounds like pyranocoumarins, polyacetylenes and essential oils, which might be useful for treatment of several chronic diseases. It has been used for centuries as a traditional medicine in Southeast Asia, but in Western countries is used as a functional food and a major ingredient of several herbal products. The genus Angelica is also known as 'female ginseng' due to its critical therapeutic role in female afflictions, such as gynecological problems...
December 7, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29215073/solution-structure-of-the-major-fish-allergen-parvalbumin-sco-j-1-derived-from-the-pacific-mackerel
#4
Hiroyuki Kumeta, Haruka Nakayama, Kenji Ogura
Although fish is an important part of the human diet, it is also a common source of food allergy. The major allergen in fish is parvalbumin, a well-conserved Ca2+-binding protein found in the white muscle of many fish species. Here, we studied the solution structure of the parvalbumin Sco j 1, derived from the Pacific mackerel, using nuclear magnetic resonance spectroscopy. We mapped the IgE-binding epitope proposed in a recent study onto the present structure. Interestingly, three of four residues, which were elucidated as key residues of the IgE-binding epitope, were exposed to solvent, whereas one residue faced the inside of the molecule...
December 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29211665/food-allergy
#5
LETTER
(no author information available yet)
New England Journal of Medicine, Volume 377, Issue 23, Page 2294-2295, December 2017.
December 7, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29210450/detection-of-allergen-coding-sequences-of-kiwi-peach-and-apple-in-processed-food-by-qpcr
#6
Sara Graziano, Mariolina Gullì, Nelson Marmiroli
BACKGROUND: Food traceability becomes lifesaving for persons suffering severe allergy or intolerance, and therefore need a complete avoidance of the immune-trigger food. This paper describes how to fingerprint the presence of some allergenic species (kiwi, peach, and apple) in foods by quantitative Real-Time PCR (qPCR). RESULTS: Five DNA extraction procedures were tested on fruits and foods. The results were statistically evaluated, and discussed. Analysis by qPCR with SYBR Green was developed to detect traces of these allergenic species in foods...
December 6, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29205393/eaaci-guidelines-on-allergen-immunotherapy-ige-mediated-food-allergy
#7
G B Pajno, M Fernandez-Rivas, S Arasi, G Roberts, C A Akdis, M Alvaro-Lozano, K Beyer, C Bindslev-Jensen, W Burks, M Ebisawa, P Eigenmann, E Knol, K C Nadeau, L K Poulsen, R van Ree, A F Santos, G du Toit, S Dhami, U Nurmatov, Y Boloh, M Makela, L O'Mahony, N Papadopoulos, C Sackesen, I Agache, E Angier, S Halken, M Jutel, S Lau, O Pfaar, D Ryan, G Sturm, E-M Varga, R G van Wijk, A Sheikh, A Muraro
Food allergy can result in considerable morbidity, impairment of quality of life, and healthcare expenditure. There is therefore interest in novel strategies for its treatment, particularly food allergen immunotherapy (FA-AIT) through the oral (OIT), sublingual (SLIT), or epicutaneous (EPIT) routes. This Guideline, prepared by the European Academy of Allergy and Clinical Immunology (EAACI) Task Force on Allergen Immunotherapy for IgE-mediated Food Allergy, aims to provide evidence-based recommendations for active treatment of IgE-mediated food allergy with FA-AIT...
September 27, 2017: Allergy
https://www.readbyqxmd.com/read/29203772/integrative-transcriptomic-analysis-reveals-key-drivers-of-acute-peanut-allergic-reactions
#8
C T Watson, A T Cohain, R S Griffin, Y Chun, A Grishin, H Hacyznska, G E Hoffman, N D Beckmann, H Shah, P Dawson, A Henning, R Wood, A W Burks, S M Jones, D Y M Leung, S Sicherer, H A Sampson, A J Sharp, E E Schadt, S Bunyavanich
Mechanisms driving acute food allergic reactions have not been fully characterized. We profile the dynamic transcriptome of acute peanut allergic reactions using serial peripheral blood samples obtained from 19 children before, during, and after randomized, double-blind, placebo-controlled oral challenges to peanut. We identify genes with changes in expression triggered by peanut, but not placebo, during acute peanut allergic reactions. Network analysis reveals that these genes comprise coexpression networks for acute-phase response and pro-inflammatory processes...
December 5, 2017: Nature Communications
https://www.readbyqxmd.com/read/29203234/development-of-a-brief-assessment-of-activity-limitations-in-children-with-food-allergy
#9
Catherine C Peterson, Lauren E Harrison
No abstract text is available yet for this article.
December 1, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29202923/allergens-an-enhanced-focus
#10
Kristen Spotz
Food Allergy Awareness Week was created with the purpose of placing a spotlight on the seriousness of food allergies. Recognized in the United States in mid-May every year, Food Allergy Awareness Week serves as a reminder of the over 15 million Americans who suffer from food allergies. The importance of allergies and allergen labeling can be seen when looking at U.S. Food and Drug Administration recall data: of the 764 recalls in 2016, 305 (representing more than 40%) were due to undeclared allergens. However, recalls for undeclared allergens are a complex issue with numerous factors...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29202922/simultaneous-analysis-of-multiple-allergens-in-food-products-by-lc-ms-ms
#11
Lee Sun New, Andre Schreiber, Jianru Stahl-Zeng, Hua-Fen Liu
There is currently no cure for food allergies, and sufferers can only rely on the correct labeling of foods toavoid allergens. Hence, it is important that analytical methods are sensitive and accurate enough to screen for the presence of multiple allergens in food products. In this study, we developed an LC-tandem MS method that is able to simultaneously screen or quantify the signature tryptic peptides of multiple allergen commodities. This method is capable of screening and identifying egg white, skim milk, peanut, soy, and tree nuts (almond, Brazil nut, cashew, hazelnut, pecan, pine nut, pistachio, and walnut) at a detection limit of 10 ppm in incurred bread and cookies...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29202919/stakeholders-guidance-document-for-consumer-analytical-devices-with-a-focus-on-gluten-and-food-allergens
#12
Bert Popping, Laura Allred, François Bourdichon, Kurt Brunner, Carmen Diaz-Amigo, Patricia Galan-Malo, Markus Lacorn, Jennifer North, Salvatore Parisi, Adrian Rogers, Jennifer Sealy-Voyksner, Tricia Thompson, Jupiter Yeung
Until recently, analytical tests for food were performed primarily in laboratories, but technical developmentsnow enable consumers to use devices to test their food at home or when dining out. Current consumer devices for food can determine nutritional values, freshness, and, most recently, the presence of food allergens and substances that cause food intolerances. The demand for such products is driven by an increase in the incidence of food allergies, as well as consumer desire for more information about what is in their food...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29202918/almond-or-mahaleb-orthogonal-allergen-analysis-during-a-live-incident-investigation-by-elisa-molecular-biology-and-protein-mass-spectrometry
#13
Michael J Walker, Malcolm Burns, Milena Quaglia, Gavin Nixon, Christopher J Hopley, Kirstin M Gray, Victoria Moore, Malvinder Singh, Simon Cowen
It is now well known that an incident investigated in the United Kingdom in 2015 of cumin alleged to be contaminated with almond, a risk for people with almond allergy, was caused by the Prunus species, Prunus mahaleb. In the United Kingdom, the Government Chemist offers a route of technical appeal from official findings in the food control system. Findings of almond in two official samples, cumin and paprika, which had prompted action to exclude the consignments from the food chain, were so referred. Herein are described the approaches deployed to resolve the analytical issues during the investigation of the incidents...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29202914/integrating-allergen-analysis-within-a-risk-assessment-framework-approaches-to-development-of-targeted-mass-spectrometry-methods-for-allergen-detection-and-quantification-in-the-ifaam-project
#14
Chiara Nitride, Victoria Lee, Ivona Baricevic-Jones, Karine Adel-Patient, Sabine Baumgartner, E N Clare Mills
Allergen analysis is central to implementing and monitoring food allergen risk assessment and management processes by the food industry, but current methods for the determination of allergens in foods give highly variable results. The European Union-funded "Integrated Approaches to Food Allergen and Allergy Risk Management" (iFAAM) project has been working to address gaps in knowledge regarding food allergen management and analysis, including the development of novel MS and immuno-based allergen determination methods...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29202913/ilsi-europe-s-food-allergy-task-force-from-defining-the-hazard-to-assessing-the-risk-from-food-allergens
#15
René R W Crevel, Stefan Ronsmans, Cyril F M Marsaux, Diána Bánáti
The International Life Sciences Institute (ILSI) Europe Food Allergy Task Force was founded in response to early public concerns about the growing impact of food allergies almost coincidentally with the publication of the 1995 Food and Agriculture Organization-World Health Organization Technical Consultation on Food Allergies. In line with ILSI principles aimed to foster collaboration between stakeholders to promote consensus on science-based approaches to food safety and nutrition, the task force has played a central role since then in the development of risk assessment for food allergens...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29202910/a-targeted-lc-ms-ms-method-for-the-simultaneous-detection-and-quantitation-of-egg-milk-and-peanut-allergens-in-sugar-cookies
#16
Chelsea C Boo, Christine H Parker, Lauren S Jackson
Food allergy is a growing public health concern, with many individuals reporting allergies to multiple food sources. Compliance with food labeling regulations and prevention of inadvertent cross-contact in manufacturing requires the use of reliable methods for the detection and quantitation of allergens in processed foods. In this work, a novel liquid chromatography-tandem mass spectrometry multiple-reaction monitoring method for multiallergen detection and quantitation of egg, milk, and peanut was developed and evaluated in an allergen-incurred baked sugar cookie matrix...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29202908/japanese-food-allergen-labeling-regulation-an-update
#17
Masahiro Shoji, Reiko Adachi, Hiroshi Akiyama
The Japanese food allergen labeling regulation was designed to match real Japanese food allergy circumstancesand also to be enforced effectively; thus, (1) regulated food allergens were selected by prevalence and seriousness according to food allergy surveys in Japan; (2) the detection criterion for ELISA monitoring, 10 μg food allergen protein/g (or mL) food, was set up as the threshold value to regulate commercial prepackaged foods; and (3) official food allergen analytical methods, which can determine the threshold value accurately, were developed...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29202906/managing-food-allergens-in-the-u-k-retail-supply-chain
#18
Michael J Walker, M Hazel Gowland, John Points
The U.K. food and grocery market is highly significant financially and dominated by 10 retailers within a regulated and extremely economically competitive environment. We summarize the approach of U.K. retailers to allergen risk assessment (RA) and risk management (RM) within the U.K. legal framework and explore public visibility of retailers' allergen policies. RA and RM of allergens appear effective in curtailing retail-triggered severe food allergy reactions. However, allergen recalls remain high, precautionary allergen labeling (PAL) remains an area of confusion, and there is no consistent Web-based provision of information for consumers who have allergies...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29202903/food-allergen-management-in-australia
#19
Martina Koeberl, Dean Clarke, Katrina J Allen, Fiona Fleming, Lisa Katzer, N Alice Lee, Andreas L Lopata, Maria Said, Pieter Scheelings, Neil Shepherd, Robin Sherlock, James Roberts
Food allergies are increasing globally, including numbers of allergens, the sensitization rate, and the prevalence rate. To protect food-allergic individuals in the community, food allergies need to be appropriately managed. This paper describes current Australian food allergen management practices. In Australia, the prevalence of food allergies, the anaphylaxis rate, and the fatal anaphylaxis rate are among the highest in the world. Interagency and stakeholder collaboration is facilitated and enhanced as Australia moves through past, current, and ongoing food allergen challenges...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29202901/european-regulations-for-labeling-requirements-for-food-allergens-and-substances-causing-intolerances-history-and-future
#20
Bert Popping, Carmen Diaz-Amigo
Food allergens and intolerances have been diagnosed by doctors for decades, but have received heightened attention in the last two decades because diagnosis and awareness have increased. Consequently, regulators in many jurisdictions have addressed this topic by introducing labeling requirements for substances causing allergies and intolerance reactions in affected individuals. Mandatory labeling of food allergens allows persons suffering from these to make informed choices. However, regulations in some geographic areas have resulted in significant problems for manufacturers as well as consumers...
December 5, 2017: Journal of AOAC International
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