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https://www.readbyqxmd.com/read/28227991/mr-conditional-safety-assessment-of-implanted-medical-devices-advantages-of-computational-human-phantoms
#1
James E Brown, Rui Qiang, Paul J Stadnik, Larry J Stotts, Jeffrey A Von Arx, James E Brown, Rui Qiang, Paul J Stadnik, Larry J Stotts, Jeffrey A Von Arx, Rui Qiang, Paul J Stadnik, Larry J Stotts, Jeffrey A Von Arx, James E Brown
Until recently, patients with active implantable medical devices (AIMDs) have been contraindicated for magnetic resonance imaging (MRI). Current efforts to demonstrate safety of these devices separate the interaction of the device and MRI into several hazards. For several of these hazards, computational human phantoms (CHPs) are used to provide conservative conditions for a risk-based analysis. This use of CHPs for the identification of conservative conditions provides a substantial benefit to the assessment of MR conditional safety over experimental techniques, as the evaluation of millions of test cases is possible in simulation, but impractical (due to economic constraints) and, in some cases, unethical for an experimental effort...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227976/user-intent-prediction-with-a-scaled-conjugate-gradient-trained-artificial-neural-network-for-lower-limb-amputees-using-a-powered-prosthesis
#2
Richard B Woodward, John A Spanias, Levi J Hargrove, Richard B Woodward, John A Spanias, Levi J Hargrove, John A Spanias, Richard B Woodward, Levi J Hargrove
Powered lower limb prostheses have the ability to provide greater mobility for amputee patients. Such prostheses often have pre-programmed modes which can allow activities such as climbing stairs and descending ramps, something which many amputees struggle with when using non-powered limbs. Previous literature has shown how pattern classification can allow seamless transitions between modes with a high accuracy and without any user interaction. Although accurate, training and testing each subject with their own dependent data is time consuming...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227974/heart-rate-variability-as-a-biomarker-for-sedation-depth-estimation-in-icu-patients
#3
Sunil B Nagaraj, Sowmya M Ramaswamy, Siddharth Biswal, Emily J Boyle, David W Zhou, Lauren M Mcclain, Eric S Rosenthal, Patrick L Purdon, M Brandon Westover, Sunil B Nagaraj, Sowmya M Ramaswamy, Siddharth Biswal, Emily J Boyle, David W Zhou, Lauren M Mcclain, Eric S Rosenthal, Patrick L Purdon, M Brandon Westover, M Brandon Westover, Sunil B Nagaraj, Siddharth Biswal, Sowmya M Ramaswamy, Lauren M Mcclain, David W Zhou, Emily J Boyle, Patrick L Purdon, Eric S Rosenthal
An automated patient-specific system to classify the level of sedation in ICU patients using heart rate variability signal is presented in this paper. ECG from 70 mechanically ventilated adult patients with administered sedatives in an ICU setting were used to develop a support vector machine based system for sedation depth monitoring using several heart rate variability measures. A leave-one-subject-out cross validation was used for classifier training and performance evaluations. The proposed patient-specific system provided a sensitivity, specificity and an AUC of 64%, 84...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227951/smartsock-a-wearable-platform-for-context-aware-assessment-of-ankle-edema
#4
Ramin Fallahzadeh, Mahdi Pedram, Hassan Ghasemzadeh, Ramin Fallahzadeh, Mahdi Pedram, Hassan Ghasemzadeh
Ankle edema an important symptom for monitoring patients with chronic systematic diseases. It is an important indicator of onset or exacerbation of a variety of diseases that disturb cardiovascular, renal, or hepatic system such as heart, liver, and kidney failure, diabetes, etc. The current approaches toward edema assessment are conducted during clinical visits. In-clinic assessments, in addition to being burdensome and expensive, are sometimes not reliable and neglect important contextual factors such as patient's physical activity level and body posture...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227931/long-range-correlations-in-amplitude-variability-of-hf-and-lf-components-of-heart-rate-variability
#5
Yuki Miki, Yasuyuki Suzuki, Eiichi Watanabe, Junichiro Hayano, Yoshiharu Yamamoto, Taishin Nomura, Ken Kiyono, Yuki Miki, Yasuyuki Suzuki, Eiichi Watanabe, Junichiro Hayano, Yoshiharu Yamamoto, Taishin Nomura, Ken Kiyono
For the assessment of autonomic nervous system activity based on heart rate variability (HRV) analysis, characteristics of high-frequency (HF; 0.15 to 0.4 Hz) and low-frequency (LF; 0.04 to 0.15 Hz) components have been widely employed. HF and LF band powers quantified by power spectral analysis have most commonly been used in the conventional studies; the physiological significance of these measures has also been extensively studied. However, nonlinear characteristics of HF and LF components have not been well established...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227922/evaluation-of-effects-of-electrical-stimulation-in-the-retina-with-optical-coherence-tomography
#6
A Gonzalez-Calle, J D Weiland, A Gonzalez-Calle, J D Weiland, A Gonzalez-Calle, J D Weiland
Retinal prostheses provide the capability to blind patients to detect motion and locate large objects. To avoid activating axons of passage, which can create streak-like perceptions, long pulse stimulation can be used to bypass axons and achieve focal retinal activation. Safety is a concern because long pulses require more charge than short pulses to elicit a response from neural tissue. Future implants will require smaller electrodes to improve resolution, but increased charge density may result, which is another safety concern...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227916/development-and-pilot-clinical-evaluation-of-a-haptic-based-perception-empathy-biofeedback-device-for-gait-rehabilitation
#7
Kenta Saichi, Kazuhiro Yasuda, Yu Kitaji, Naomi Kaibuki, Hiroyasu Iwata, Kenta Saichi, Kazuhiro Yasuda, Yu Kitaji, Naomi Kaibuki, Hiroyasu Iwata
Recent studies have shown that haptic feedback on the body, either at or away from the desired gait parameter to be changed, can improve gait performance. Here we introduced a haptic-based biofeedback device to supplement the foot pressure information of a paretic foot with a wearable vibrotactile biofeedback device attached to the back. This system provides information regarding a patient's foot pressure pattern to the patient and physical therapist. Therefore, the biofeedback system can share information regarding abnormal gait patterns between patients and therapists...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227873/a-comprehensive-reputation-mechanism-for-ubiquitous-healthcare-environment-exploiting-cloud-model
#8
Georgia Athanasiou, Dimitrios Lymberopoulos, Georgia Athanasiou, Dimitrios Lymberopoulos, Dimitrios Lymberopoulos, Georgia Athanasiou
Absence of trust foundations may outweigh benefits of ubiquitous and personalized mental healthcare supervision provided within a Ubiquitous Healthcare environment (UH). Trust is composed by patient's Personal Interaction Experience (PIE) and social entourage accumulated PIE, i.e. Reputation (R). In this paper, a cloud-based Reputation mechanism is proposed. Since PIE is the elementary trust information source, also an Updating mechanism of PIE, is introduced, in this paper. Cloud materialization of combined mechanisms provides adaptability to UH Providers' dynamic behavior, facilitates detection of milking behaviors and complex malicious attacks while meets the challenge of limited accuracy in case of data sparseness...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227859/application-of-meg-coherence-in-lateralization-of-mtle
#9
Mohammad R Nazem-Zadeh, Susan M Bowyer, John E Moran, Esmaeil Davoodi-Bojd, Andrew Zillgitt, Hassan Bagher-Ebadian, Fariborz Mahmoudi, Kost V Elisevich, Hamid Soltanian-Zadeh, Mohammad R Nazem-Zadeh, Susan M Bowyer, John E Moran, Esmaeil Davoodi-Bojd, Andrew Zillgitt, Hassan Bagher-Ebadian, Fariborz Mahmoudi, Kost V Elisevich, Hamid Soltanian-Zadeh, Susan M Bowyer, Hassan Bagher-Ebadian, Esmaeil Davoodi-Bojd, Andrew Zillgitt, Fariborz Mahmoudi, John E Moran, Hamid Soltanian-Zadeh, Kost V Elisevich, Mohammad R Nazem-Zadeh
Magnetoencephalography (MEG) is a noninvasive imaging method for localization of focal epileptiform activity in patients with epilepsy. This study investigates the cerebral functional abnormalities quantified by MEG coherence laterality in mesial temporal lobe epilepsy (mTLE). Resting state MEG data was analyzed using MEG coherence source imaging (MEG-CSI) method to determine the coherence in 54 anatomical sites in 12 adult mTLE patients and 12 age- and gender-matched controls. MEG coherence laterality, after Bonferroni adjustment, showed significant differences for right versus left mTLE in insular cortex and both lateral orbitofrontal and superior temporal gyri (p<;0...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227830/an-adaptive-model-approach-for-quantitative-wrist-rigidity-evaluation-during-deep-brain-stimulation-surgery
#10
Sofia Assis, Pedro Costa, Maria Jose Rosas, Rui Vaz, Joao Paulo Silva Cunha, Sofia Assis, Pedro Costa, Maria Jose Rosas, Rui Vaz, Joao Paulo Silva Cunha, Maria Jose Rosas, Joao Paulo Silva Cunha, Sofia Assis, Rui Vaz, Pedro Costa
Intraoperative evaluation of the efficacy of Deep Brain Stimulation includes evaluation of the effect on rigidity. A subjective semi-quantitative scale is used, dependent on the examiner perception and experience. A system was proposed previously, aiming to tackle this subjectivity, using quantitative data and providing real-time feedback of the computed rigidity reduction, hence supporting the physician decision. This system comprised of a gyroscope-based motion sensor in a textile band, placed in the patients hand, which communicated its measurements to a laptop...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227789/addressing-drug-drug-and-drug-food-interactions-through-personalized-empowerment-services-for-healthcare
#11
Marios Spanakis, Emmanouil G Spanakis, Haridimos Kondylakis, Stelios Sfakianakis, Irini Genitsaridi, Vangelis Sakkalis, Manolis Tsiknakis, Kostas Marias, Marios Spanakis, Emmanouil G Spanakis, Haridimos Kondylakis, Stelios Sfakianakis, Irini Genitsaridi, Vangelis Sakkalis, Manolis Tsiknakis, Kostas Marias, Manolis Tsiknakis, Haridimos Kondylakis, Kostas Marias, Stelios Sfakianakis, Irini Genitsaridi, Emmanouil G Spanakis, Vangelis Sakkalis, Marios Spanakis
Personalized healthcare systems support the provision of timely and appropriate information regarding healthcare options and treatment alternatives. Especially for patients that receive multi-drug treatments a key issue is the minimization of the risk of adverse effects due to drug-drug interactions (DDIs). DDIs may be the result of doctor prescribed drugs but also due to self-medication of conventional drugs, alternative medicines, food habits, alcohol or smoking. It is therefore crucial for personalized health systems, apart from assisting physicians for optimal prescription practices, to also provide appropriate information for individual users for drug-drug interactions or similar information regarding risks for modulation of the ensuing treatment...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227780/impact-of-prostate-biopsy-tumor-amount-on-imaging-based-prognostics-employing-transductive-semi-supervised-regression
#12
Faisal M Khan, Casimir A Kulikowski, Faisal M Khan, Casimir A Kulikowski, Casimir A Kulikowski, Faisal M Khan
For newly diagnosed prostate cancer patients with a positive biopsy, there are a variety of treatment options to consider. To aid physicians and patients in their decision making, a variety of predictive assays have emerged within the last decade, many of them imaging based. These assays build predictive models for survival analysis to provide personalized risk assessments for the patients. However, there have rarely been any published studies on how the amount of tumor in the positive prostate biopsy affects the predictive power of these imaging based assays...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227779/revealing-oral-medication-patterns-from-reconstructed-long-term-medication-history-of-type-2-diabetes
#13
Purnomo Husnul Khotimah, Yuichi Sugiyama, Masatoshi Yoshikawa, Akihiro Hamasaki, Kazuya Okamoto, Tomohiro Kuroda, Purnomo Husnul Khotimah, Yuichi Sugiyama, Masatoshi Yoshikawa, Akihiro Hamasaki, Kazuya Okamoto, Tomohiro Kuroda, Kazuya Okamoto, Purnomo Husnul Khotimah, Yuichi Sugiyama, Akihiro Hamasaki, Masatoshi Yoshikawa, Tomohiro Kuroda
With the growing attention to evidence-based medical guideline development, longitudinal analysis of Electronic Medical Records (EMR) has become a good tool for providing insight into and new knowledge on the existing therapy. For chronic diseases, longitudinal analysis of medication history plays a key role in reaching this goal. However, raw medication data in EMR are not suitable for longitudinal analysis for several reasons. First, many prescriptions have a short duration. Second, the prescription duration may have a gap or overlap with other prescription durations...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227768/measures-of-the-brain-functional-network-that-correlate-with-alzheimer-s-neuropsychological-test-scores-an-fmri-and-graph-analysis-study
#14
Soroosh Golbabaei, Amin Dadashi, Hamid Soltanian-Zadeh, Soroosh Golbabaei, Amin Dadashi, Hamid Soltanian-Zadeh, Soroosh Golbabaei, Amin Dadashi, Hamid Soltanian-Zadeh
Neural degeneration in Alzheimer's disease (AD) leads to structural topology deformation that in turn changes brain functionality. The main aim of the present study is to find the brain's functional connectivity network (FCN) correlates of Alzheimer's psychological test scores. To this end, the brain's FCN is extracted from the resting state functional magnetic resonance images (rs-fMRI) of healthy controls and patients with AD and represented as a graph. Then, network measures are calculated from the graphs...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227761/application-of-dti-connectivity-in-lateralization-of-mtle
#15
Mohammad R Nazem-Zadeh, Susan M Bowyer, John E Moran, Esmaeil Davoodi-Bojd, Andrew Zillgitt, Hassan Bagher-Ebadian, Fariborz Mahmoudi, Kost V Elisevich, Hamid Soltanian-Zadeh, Mohammad R Nazem-Zadeh, Susan M Bowyer, John E Moran, Esmaeil Davoodi-Bojd, Andrew Zillgitt, Hassan Bagher-Ebadian, Fariborz Mahmoudi, Kost V Elisevich, Hamid Soltanian-Zadeh, Susan M Bowyer, Hassan Bagher-Ebadian, Esmaeil Davoodi-Bojd, Andrew Zillgitt, Fariborz Mahmoudi, John E Moran, Hamid Soltanian-Zadeh, Kost V Elisevich, Mohammad R Nazem-Zadeh
Diffusion tensor imaging (DTI) is a noninvasive imaging method for measuring the diffusion properties of the underlying white matter tracts through which epileptiform activity is propagated. This study investigates the structural abnormalities quantified by DTI in mesial temporal lobe epilepsy (mTLE). Fiber tracts passing through 54 anatomical sites in 12 adult mTLE patients and 12 age- and gender-matched controls were identified using DTI tractography. DTI nodal degree (ND) and laterality index were then calculated...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227758/mining-cross-frequency-coupling-microstates-from-resting-state-meg-an-application-to-mild-traumatic-brain-injury
#16
Marios Antonakakis, Stavros I Dimitriadis, Michalis Zervakis, Andrew C Papanicolaou, George Zouridakis, Marios Antonakakis, Stavros I Dimitriadis, Michalis Zervakis, Andrew C Papanicolaou, George Zouridakis, Michalis Zervakis, Marios Antonakakis, George Zouridakis, Andrew C Papanicolaou, Stavros I Dimitriadis
Recent studies have investigated the possible role of dynamic functional connectivity and the role of cross-frequency coupling (CFC) to provide the substrate for reliable biomarkers of brain disorders. In this study, we analyzed time-varying CFC profiles from resting state Magnetoencephal-ographic recordings of 30 mild Traumatic Brain Injury (mTBI) patients and 50 normal controls. Interactions among sensors at specific pairs of frequency bands were computed via estimation of phase-to-amplitude couplings. We then computed time-varying functional connectivity graphs that were described in terms of segregation (local efficiency, LE) and integration (global efficiency, GE) and mapped those graphs to time series of GE/LE estimates...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227736/dermatological-tracking-of-chronic-acne-treatment-effectiveness
#17
Sergiu Lucut, Michael R Smith, Sergiu Lucut, Michael R Smith, Michael R Smith, Sergiu Lucut
Acne can lead to severe physical and psychological implications on chronic sufferers if not treated promptly and properly. Ramli et al. proposed a k-means cluster based algorithm to provide computer-assisted support for the manual grading of digital images. We propose an improved, automated, and more objective, grading method which involves optimizing the k-means clustering algorithm by identifying the actual number of clusters rather than basing analysis on a fixed K= 3 assumption for all images. The Hough transform was used to further analyze the found acne cluster leading to an approach to more accurately automatically determine the number and type of lesions...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227727/the-effect-of-data-exchange-protocols-on-decision-support-systems-for-heart-sounds
#18
P Gomes, S Faria, M Coimbra, P Gomes, S Faria, M Coimbra, P Gomes, S Faria, M Coimbra
Heart auscultation is one of the basic exams performed during a patient physical examination, but it is also one that has a high skill ceiling. Decision support systems can provide physicians with a tool that can help to reduce the demanding skill requirements of this exam. Nevertheless, this second opinion needs to be delivered in a timely interval in order to be truly useful for a physician. To do this we need not only optimized algorithms, but also a well designed system. In this paper, we have studied how two different data exchange protocols, that define how data should be transferred from an acquisition to a process module, can impact the celerity of delivering second opinion to a physician...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227722/alzcare-an-information-system-for-screening-management-and-tracking-of-demented-patients
#19
Vasilios Protopappas, Konstantinos Tsiouris, Maria Chondrogiorgi, Christos Tsironis, Spiridon Konitsiotis, Dimitrios I Fotiadis, Vasilios Protopappas, Konstantinos Tsiouris, Maria Chondrogiorgi, Christos Tsironis, Spiridon Konitsiotis, Dimitrios I Fotiadis, Spiridon Konitsiotis, Dimitrios I Fotiadis, Vasilios Protopappas, Konstantinos Tsiouris, Maria Chondrogiorgi, Christos Tsironis
The ALZCARE project aims at assisting people at risk or already suffering of dementia, their family and health professionals in the dementia care pathway by providing an integrated ICT-enabled information System. The system consists of a mobile platform for screening people at risk, a Clinical Information System and a satellite-based patient tracking system. The system is currently on the evaluation phase focusing on addressing the needs of citizens of the cross-border areas of Greece and Albania.
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227709/bayesian-gaussian-processes-for-identifying-the-deteriorating-patient
#20
Glen Wright Colopy, Marco A F Pimentel, Stephen J Roberts, David A Clifton, Glen Wright Colopy, Marco A F Pimentel, Stephen J Roberts, David A Clifton, Glen Wright Colopy, Marco A F Pimentel, Stephen J Roberts, David A Clifton
The step-down unit (SDU) is a high-acuity hospital environment, to which patients may be sent after discharge from the intensive care unit (ICU). About 1- in-7 patients will deteriorate in the SDU and require emergency readmission to the ICU. Upon readmission, these patients experience significantly higher mortality risks and lengths of stay. Gaussian process regression (GPR) models are proposed as a flexible, principled, probabilistic method to address the clinical need to monitor continuously patient time-series of vital signs acquired in the SDU...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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