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https://www.readbyqxmd.com/read/28644688/intraosseous-administration-of-antidotes-a-systematic-review
#1
Audrée Elliott, Pierre-André Dubé, Amélie Cossette-Côté, Laura Patakfalvi, Eric Villeneuve, Martin Morris, Sophie Gosselin
CONTEXT: Intraosseous (IO) access is an established route of administration in resuscitation situations. Patients with serious poisoning presenting to the emergency department may require urgent antidote therapy. However, intravenous (IV) access is not always readily available. OBJECTIVE: This study reviews the current evidence for IO administration of antidotes that could be used in poisoning. The primary outcome was mortality as a surrogate of efficacy. Secondary outcomes included hemodynamic variables, electrocardiographic variables, neurological status, pharmacokinetics outcomes, and adverse effects as defined by each article...
June 23, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28641952/the-effect-of-tissue-segmented-attenuation-maps-on-pet-quantification-with-a-special-focus-on-large-arteries
#2
A Mota-Cobian, J C Alonso-Farto, L Fernández-Friera, J Sánchez-González, B López-Melgar, L J Jiménez-Borreguero, V Fuster, J Ruiz-Cabello, S España
OBJECTIVES: Accuracy on quantitative PET image analysis relies on the correct application of attenuation correction which is one of the major challenges for PET/MRI that remains to be solved. The purpose of this study is to evaluate the effect of MRI-based attenuation maps and the use of flexible coils on the quantitative accuracy of PET images with a special focus on large arteries. MATERIALS AND METHODS: PET/CT data from eight oncologic patients was used. PET data was reconstructed using attenuation maps with different level of detail emulating several approaches available on current PET/MRI scanners...
June 19, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28633874/proportional-bias-between-dual-energy-x-ray-absorptiometry-and-bioelectrical-impedance-analysis-varies-based-on-sex-in-active-adults-consuming-high-and-low-carbohydrate-diets
#3
Grant M Tinsley
Dual-energy x-ray absorptiometry (DXA) and bioelectrical impedance analysis (BIA) are common methods of body composition assessment, but the agreement between these methods varies. Bias between DXA and single-frequency BIA was evaluated at 6 different time points in 48 active male and female adults consuming standardized high- and low-carbohydrate diets. It was hypothesized that fixed and proportional biases exist between DXA and BIA but that the extent of bias does not differ based on sex. Substantial fixed bias was present for estimates obtained by DXA and BIA, and both men and women exhibited proportional bias for fat mass (FM) and fat-free mass (FFM)...
June 2017: Nutrition Research
https://www.readbyqxmd.com/read/28601451/effect-of-uncertainty-in-composition-and-weight-measures-in-control-of-cheese-yield-and-fat-loss-in-large-cheese-factories
#4
Brenda Margolies, Michael C Adams, Joice Pranata, Kathleen Gondoutomo, David M Barbano
Our objective was to develop a computer-based cheese yield, fat recovery, and composition control performance measurement system to provide quantitative performance records for a Cheddar and mozzarella cheese factory. The system can be used to track trends in performance of starter cultures and vats, as well as systematically calculate theoretical yield. Yield equations were built into the spreadsheet to evaluate cheese yield performance and fat losses in a cheese factory. Based on observations in commercial cheese factories, sensitivity analysis was done to demonstrate the sensitivity of cheese factory performance to analytical uncertainty of data used in the evaluation...
June 7, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28598587/challenges-in-model-development-for-meat-composition-using-multipoint-nir-spectroscopy-from-at-line-to-in-line-monitoring
#5
Y Dixit, Maria P Casado-Gavalda, R Cama-Moncunill, P J Cullen, Carl Sullivan
This study evaluates the efficiency of multipoint near-infrared spectroscopy (NIRS) to predict the fat and moisture content of minced beef samples both in at-line and on-line modes. Additionally, it aims at identifying the obstacles that can be encountered in the path of performing in-line monitoring. Near-infrared (NIR) reflectance spectra of minced beef samples were collected using an NIR spectrophotometer, employing a Fabry-Perot interferometer. Partial least squares regression (PLSR) models based on reference values from proximate analysis yielded calibration coefficients of determination (Rc2) of 0...
June 9, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28596551/automated-segmentation-of-human-cervical-supraclavicular-adipose-tissue-in-magnetic-resonance-images
#6
Elin Lundström, Robin Strand, Anders Forslund, Peter Bergsten, Daniel Weghuber, Håkan Ahlström, Joel Kullberg
Human brown adipose tissue (BAT), with a major site in the cervical-supraclavicular depot, is a promising anti-obesity target. This work presents an automated method for segmenting cervical-supraclavicular adipose tissue for enabling time-efficient and objective measurements in large cohort research studies of BAT. Fat fraction (FF) and R2(*) maps were reconstructed from water-fat magnetic resonance imaging (MRI) of 25 subjects. A multi-atlas approach, based on atlases from nine subjects, was chosen as automated segmentation strategy...
June 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28596227/outcomes-with-perioperative-fat-emulsions-containing-omega-3-fatty-acid-a-meta-analysis-of-randomized-controlled-trials
#7
Hye Jung Bae, Gwan Young Lee, Jong-Mi Seong, Hye Sun Gwak
PURPOSE: Results of a meta-analysis of data from clinical studies comparing patient outcomes and hospital length of stay (LOS) in surgical patients receiving fish oil (FO)-containing i.v. fat emulsions (IVFEs) versus non-FO-containing IVFEs are presented. METHODS: Computerized searches of the MEDLINE, Embase, and Coch rane CENTRAL databases were performed in August 2014 to identify English-language articles on randomized controlled trials (RCTs) comparing FO-containing and non-FO-containing IVFEs in adult surgical patients receiving parenteral nutrition...
June 15, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28593731/multimodal-3d-imaging-based-on-%C3%AE-mri-and-%C3%AE-ct-techniques-bridges-the-gap-with-histology-in-visualization-of-the-bone-regeneration-process
#8
R Sinibaldi, A Conti, B Sinjari, S Spadone, R Pecci, M Palombo, V S Komlev, M G Ortore, G Tromba, S Capuani, F De Luca, S Caputi, T Traini, S Della Penna
Bone repair/regeneration is usually investigated through x-ray computed microtomography (μCT) supported by histology of extracted samples, to analyze biomaterial structure and new bone formation processes. Magnetic Resonance Imaging (μMRI) shows a richer tissue contrast than μCT, despite at lower resolution, and could be combined with μCT in the perspective of conducting non-destructive 3D investigations of bone. A pipeline designed to combine μMRI and μCT images of bone samples is here described and applied on samples of extracted human jawbone core following bone graft...
June 7, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28580427/incidental-finding-of-low-brown-adipose-tissue-activity-in-endurance-trained-individuals-methodological-considerations-for-positron-emission-tomography
#9
Eric T Trexler, Drew McCallister, Abbie E Smith-Ryan, Rosa T Branca
Brown adipose tissue (BAT) in adults has been shown to have a meaningful impact on energy expenditure and cold-induced thermogenesis. Data from rodent research have suggested that exercise may be a promising method of increasing BAT activity, with potential applications to the treatment and prevention of obesity and diabetes. However, emerging human research using positron emission tomography (PET) with [18F] Fluorodeoxyglucose (FDG) has identified lower BAT activity in endurance-trained athletes compared to sedentary controls, despite similar metabolic rate responses to cold exposure...
March 2017: Journal of Nature and Science
https://www.readbyqxmd.com/read/28538363/the-effect-of-alpha-linolenic-acid-on-glycemic-control-in-individuals-with-type-2-diabetes-a-systematic-review-and-meta-analysis-of-randomized-controlled-clinical-trials
#10
Elena Jovanovski, Dandan Li, Hoang Vi Thanh Ho, Vladimir Djedovic, Any de Castro Ruiz Marques, Esra Shishtar, Sonia Blanco Mejia, John L Sievenpiper, Russell J de Souza, Lea Duvnjak, Vladimir Vuksan
BACKGROUND: Polyunsaturated fats (PUFAs) have been shown to reduce type 2 diabetes (T2DM) risk and improve insulin responsiveness in T2DM subjects, but whether the plant sources of omega-3 PUFA (alpha-linolenic acid [ALA]) have an effect on glycemic control requires further investigation. METHODS: The parameters of interest were glycated hemoglobin (HbA1c), fasting blood glucose (FBG), fasting blood insulin (FBI), homeostatic model assessment for insulin resistance (HOMA-IR), fructosamine, and glycated albumin...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28534498/estimating-the-basal-metabolic-rate-from-fat-free-mass-in-individuals-with-motor-complete-spinal-cord-injury
#11
S M Chun, H-R Kim, H I Shin
STUDY DESIGN: Cross-sectional study. OBJECTIVES: This study aimed to validate the existing basal metabolic rate (BMR) predictive equations that include fat free mass (FFM) as an independent variable and, based on the FFM assessment, to develop a new SCI population-specific equation. SETTING: Outpatient clinic in a general hospital. METHODS: Our study group was formed of 50 individuals with chronic motor complete SCI: 27 patients with tetraplegia and 23 with paraplegia...
May 23, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28497511/effects-of-medical-trainees-weight-loss-history-on-perceptions-of-patients-with-obesity
#12
Rebecca L Pearl, Dallas Argueso, Thomas A Wadden
CONTEXT: Medical professionals often express weight-biased attitudes. Prior research suggests that people who overcome a challenge are critical of individuals who struggle to overcome the same challenge. Thus, medical trainees who have successfully achieved and maintained weight loss may express greater weight bias and more critical attitudes toward patients with obesity who fail to overcome these challenges. OBJECTIVES: This study was designed to determine the effects of medical trainees' weight-loss history on weight-biased attitudes and responses to patients with varying weight-loss outcomes...
May 11, 2017: Medical Education
https://www.readbyqxmd.com/read/28493875/effect-of-a-high-fat-diet-and-alcohol-on-cutaneous-repair-a-systematic-review-of-murine-experimental-models
#13
Daiane Figueiredo Rosa, Mariáurea Matias Sarandy, Rômulo Dias Novaes, Sérgio Luís Pinto da Matta, Reggiani Vilela Gonçalves
BACKGROUND AND PURPOSE: Chronic alcohol intake associated with an inappropriate diet can cause lesions in multiple organs and tissues and complicate the tissue repair process. In a systematic review, we analyzed the relevance of alcohol and high fat consumption to cutaneous and repair, compared the main methodologies used and the most important parameters tested. Preclinical investigations with murine models were assessed to analyze whether the current evidence support clinical trials...
2017: PloS One
https://www.readbyqxmd.com/read/28486018/development-and-validation-of-skinfold-model-for-estimation-of-body-density-for-a-safe-weight-reduction-in-young-iranian-wrestlers
#14
Sadjad Riyahi-Alam, Mohammad Ali Mansournia, Yaser Kabirizadeh, Nasrin Mansournia, Ewout Steyerberg, Ramin Kordi
BACKGROUND: Adverse effects of excessive body mass reduction among wrestlers dictate minimum weight determination through body composition. Although skinfold equations are essential to estimate body composition in the field setting, they are mostly derived from Western societies and may lack generalizability to other populations. PURPOSE: Previously published skinfold equations lacked external validity in predicting body density of Iranian wrestlers. We aimed to derive a new anthropometric model specific to young Iranian male wrestlers...
May 1, 2017: Sports Health
https://www.readbyqxmd.com/read/28477346/breast-mri-segmentation-for-density-estimation-do-different-methods-give-the-same-results-and-how-much-do-differences-matter
#15
Simon J Doran, John H Hipwell, Rachel Denholm, Björn Eiben, Marta Busana, David J Hawkes, Martin O Leach, Isabel Dos Santos Silva
PURPOSE: To compare two methods of automatic breast segmentation with each other and with manual segmentation in a large subject cohort. To discuss the factors involved in selecting the most appropriate algorithm for automatic segmentation and, in particular, to investigate the appropriateness of overlap measures (e.g., Dice and Jaccard coefficients) as the primary determinant in algorithm selection. METHODS: Two methods of breast segmentation were applied to the task of calculating MRI breast density in 200 subjects drawn from the Avon Longitudinal Study of Parents and Children, a large cohort study with an MRI component...
May 6, 2017: Medical Physics
https://www.readbyqxmd.com/read/28472859/lifestyle-interventions-for-the-treatment-of-women-with-gestational-diabetes
#16
REVIEW
Julie Brown, Nisreen A Alwan, Jane West, Stephen Brown, Christopher Jd McKinlay, Diane Farrar, Caroline A Crowther
BACKGROUND: Gestational diabetes (GDM) is glucose intolerance, first recognised in pregnancy and usually resolving after birth. GDM is associated with both short- and long-term adverse effects for the mother and her infant. Lifestyle interventions are the primary therapeutic strategy for many women with GDM. OBJECTIVES: To evaluate the effects of combined lifestyle interventions with or without pharmacotherapy in treating women with gestational diabetes. SEARCH METHODS: We searched the Pregnancy and Childbirth Group's Trials Register (14 May 2016), ClinicalTrials...
May 4, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28470972/oral-calorie-supplements-for-cystic-fibrosis
#17
REVIEW
Rosalind L Smyth, Oli Rayner
BACKGROUND: Poor nutrition occurs frequently in people with cystic fibrosis and is associated with other adverse outcomes. Oral calorie supplements are used to increase total daily calorie intake and improve weight gain. However, they are expensive and there are concerns they may reduce the amount of food eaten and not improve overall energy intake. This is an update of a previously published review. OBJECTIVES: To establish whether in people with cystic fibrosis, oral calorie supplements: increase daily calorie intake; and improve overall nutritional intake, nutritional indices, lung function, survival and quality of life...
May 4, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28464097/live-animal-assessments-of-rump-fat-and-muscle-score-in-angus-cows-and-steers-using-3-dimensional-imaging
#18
M J McPhee, B J Walmsley, B Skinner, B Littler, J P Siddell, L M Cafe, J F Wilkins, V H Oddy, A Alempijevic
The objective of this study was to develop a proof of concept for using off-the-shelf Red Green Blue-Depth (RGB-D) Microsoft Kinect cameras to objectively assess P8 rump fat (P8 fat; mm) and muscle score (MS) traits in Angus cows and steers. Data from low and high muscled cattle (156 cows and 79 steers) were collected at multiple locations and time points. The following steps were required for the 3-dimensional (3D) image data and subsequent machine learning techniques to learn the traits: 1) reduce the high dimensionality of the point cloud data by extracting features from the input signals to produce a compact and representative feature vector, 2) perform global optimization of the signatures using machine learning algorithms and a parallel genetic algorithm, and 3) train a sensor model using regression-supervised learning techniques on the ultrasound P8 fat and the classified learning techniques for the assessed MS for each animal in the data set...
April 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28456669/lumbar-muscle-structure-and-function-in-chronic-versus-recurrent-low-back-pain-a-cross-sectional-study
#19
Dorien Goubert, Robby De Pauw, Mira Meeus, Tine Willems, Barbara Cagnie, Stijn Schouppe, Jessica Van Oosterwijck, Evy Dhondt, Lieven Danneels
BACKGROUND CONTEXT: Heterogeneity exists within the low back pain (LBP) population. Some patients recover after every pain episode, whereas others suffer daily from LBP complaints. Until now, studies rarely make a distinction between recurrent low back pain (RLBP) and chronic low back pain (CLBP), although both are characterized by a different clinical picture. Clinical experiences also indicate that heterogeneity exists within the CLBP population. Muscle degeneration, like atrophy, fat infiltration, alterations in muscle fiber type, and altered muscle activity, compromises proper biomechanics and motion of the spinal units in LBP patients...
April 26, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28452292/body-weight-and-body-composition-changes-during-military-training-and-deployment-involving-the-use-of-combat-rations-a-systematic-literature-review
#20
Eliza C Tassone, Bradley A Baker
Dismounted military personnel operate in physically and psychologically demanding environments, with energy intake from combat rations often falling short of their requirements, leading to reductions in body weight and changes in body composition, which can impact both their health and performance. This review systematically investigated the effects of the continual use of combat rations for periods of 3-40 d on body weight and/or body composition in military personnel engaged in training or deployment. In all, ten databases were searched from their inception until October 2016...
March 2017: British Journal of Nutrition
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