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https://www.readbyqxmd.com/read/28910398/body-composition-and-prediction-equations-using-skinfold-thickness-for-body-fat-percentage-in-southern-brazilian-adolescents
#1
Wagner Luis Ripka, Leandra Ulbricht, Pedro Miguel Gewehr
OBJECTIVES: The purpose of this study was to: a) determine the nutritional status of Brazilian adolescents, and; b) present a skinfold thickness model (ST) to estimate body fat developed with Brazilian samples, using dual energy x-ray absorptiometry (DXA) as reference method. METHODS: The main study group was composed of 374 adolescents, and further 42 adolescents for the validation group. Weight, height, waist circumference measurements, and body mass index (BMI) were collected, as well as nine ST-biceps (BI), triceps (TR), chest (CH), axillary (AX) subscapularis (SB), abdominal (AB), suprailiac (SI), medial thigh (TH), calf (CF), and fat percentage (%BF) obtained by DXA...
2017: PloS One
https://www.readbyqxmd.com/read/28898677/difference-in-dachsous-levels-between-migrating-cells-coordinates-the-direction-of-collective-cell-migration
#2
Masaki Arata, Kaoru Sugimura, Tadashi Uemura
In contrast to extracellular chemotactic gradients, how cell-adhesion molecules contribute to directing cell migration remains more elusive. Here we studied the collective migration of Drosophila larval epidermal cells (LECs) along the anterior-posterior axis and propose a migrating cell group-autonomous mechanism in which an atypical cadherin Dachsous (Ds) plays a pivotal role. In each abdominal segment, the amount of Ds in each LEC varied along the axis of migration (Ds imbalance), which polarized Ds localization at cell boundaries...
September 11, 2017: Developmental Cell
https://www.readbyqxmd.com/read/28892458/linearity-bias-and-precision-of-hepatic-proton-density-fat-fraction-measurements-by-using-mr-imaging-a-meta-analysis
#3
Takeshi Yokoo, Suraj D Serai, Ali Pirasteh, Mustafa R Bashir, Gavin Hamilton, Diego Hernando, Houchun H Hu, Holger Hetterich, Jens-Peter Kühn, Guido M Kukuk, Rohit Loomba, Michael S Middleton, Nancy A Obuchowski, Ji Soo Song, An Tang, Xinhuai Wu, Scott B Reeder, Claude B Sirlin
Purpose To determine the linearity, bias, and precision of hepatic proton density fat fraction (PDFF) measurements by using magnetic resonance (MR) imaging across different field strengths, imager manufacturers, and reconstruction methods. Materials and Methods This meta-analysis was performed in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A systematic literature search identified studies that evaluated the linearity and/or bias of hepatic PDFF measurements by using MR imaging (hereafter, MR imaging-PDFF) against PDFF measurements by using colocalized MR spectroscopy (hereafter, MR spectroscopy-PDFF) or the precision of MR imaging-PDFF...
September 11, 2017: Radiology
https://www.readbyqxmd.com/read/28889370/semi-mechanistic-model-for-predicting-the-dosing-rate-in-children-and-neonates-for-drugs-mainly-eliminated-by-cytochrome-metabolism
#4
Lena Cerruti, Nathalie Bleyzac, Michel Tod
BACKGROUND AND OBJECTIVE: A simple approach is proposed to predict drug clearance in children when no paediatric data are available for drugs metabolised by cytochromes. METHODS: The maturation functions of cytochrome activity and binding proteins in plasma were combined with several measures of body size to describe drug clearance increase with age. The complete model and different reduced models were evaluated on a large panel of drug clearance data in children...
September 9, 2017: Clinical Pharmacokinetics
https://www.readbyqxmd.com/read/28886551/systematic-review-and-meta-analysis-of-early-life-exposure-to-di-2-ethylhexyl-phthalate-and-obesity-related-outcomes-in-rodents
#5
REVIEW
Pim Nicolaas Hubertus Wassenaar, Juliette Legler
BACKGROUND: It has been suggested that the plasticizer di(2-ethylhexyl) phthalate (DEHP) exerts obesogenic effects after pre- or perinatal exposure. OBJECTIVE: A systematic review with meta-analyses was conducted of early life exposure to DEHP, or its biologically active metabolite mono(2-ethylhexyl) phthalate (MEHP), on the obesity related outcome measures body weight, fat (pad) weight, triglycerides, free fatty acids and leptin in experimental rodent studies. METHODS: The applied methodology was pre-specified in a rigorous protocol...
August 31, 2017: Chemosphere
https://www.readbyqxmd.com/read/28882021/sarcopenia-predicts-prognosis-in-patients-with-newly-diagnosed-hepatocellular-carcinoma-independent-of-tumor-stage-and-liver-function
#6
Yeonjung Ha, Daejung Kim, Seungbong Han, Young Eun Chon, Yun Bin Lee, Mi Na Kim, Joo Ho Lee, Hana Park, Kyu Sung Rim, Seong Gyu Hwang
Purpose: To demonstrate the prognostic significance of changes in body composition in patients with newly diagnosed hepatocellular carcinoma (HCC). Materials and Methods: Patients (N=178) newly diagnosed with HCC participated in the study between 2007 and 2012. Areas of skeletal muscle and abdominal fat were directly measured using a three-dimensional workstation. Cox proportional-hazards modes were used to estimate the effect of baseline variables on overall survival...
September 4, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28843681/effect-of-genetic-and-nongenetic-factors-on-chemical-composition-of-individual-milk-samples-from-dromedary-camels-camelus-dromedarius-under-intensive-management
#7
P Nagy, Zs N Fábri, L Varga, J Reiczigel, J Juhász
The aims of the present study were to monitor the changes in gross chemical composition of individual dromedary camel milk over a 5-yr period, to provide reference values, and to determine the effect of genetic and nongenetic factors influencing camel milk composition under intensive management. A total of 1,528 lactating dromedary camels were included in the study. Animals were fed a constant diet and were milked twice a day in a herringbone parlor. Milk samples were collected at monthly intervals using a sampling device and then fat, protein, lactose, total solids (TS), and solids-nonfat (SNF) concentrations of raw camel milk were determined with an automatic milk analyzer...
August 23, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28829533/vitamin-k-supplementation-for-cystic-fibrosis
#8
REVIEW
Vanitha A Jagannath, Vidhu Thaker, Anne B Chang, Amy I Price
BACKGROUND: Cystic fibrosis is a genetic disorder which can lead to multiorgan dysfunction. Malabsorption of fat and fat-soluble vitamins (A, D, E, K) may occur and can cause subclinical deficiencies of some of these vitamins. Vitamin K is known to play an important role in both blood coagulation and bone formation. Supplementation with vitamin K appears to be one way of addressing the deficiency, but there is very limited agreement on the appropriate dose and frequency of use of these supplements...
August 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28809927/in-middle-aged-and-old-obese-patients-training-intervention-reduces-leptin-level-a-meta-analysis
#9
Ildikó Rostás, László Pótó, Péter Mátrai, Péter Hegyi, Judit Tenk, András Garami, Anita Illés, Margit Solymár, Erika Pétervári, Ákos Szűcs, Andrea Párniczky, Dániel Pécsi, Zoltán Rumbus, Csaba Zsiborás, Nóra Füredi, Márta Balaskó
BACKGROUND: Leptin is one of the major adipokines in obesity that indicates the severity of fat accumulation. It is also an important etiological factor of consequent cardiometabolic and autoimmune disorders. Aging has been demonstrated to aggravate obesity and to induce leptin resistance and hyperleptinemia. Hyperleptinemia, on the other hand, may promote the development of age-related abnormalities. While major weight loss has been demonstrated to ameliorate hyperleptinemia, obese people show a poor tendency to achieve lasting success in this field...
2017: PloS One
https://www.readbyqxmd.com/read/28795491/role-of-handedness-on-forearm-skin-tissue-dielectric-constant-tdc-in-relation-to-detection-of-early-stage-breast-cancer-related-lymphedema
#10
Harvey N Mayrovitz, Madeline Fasen, Paige Spagna, Jennifer Wong
skin tissue dielectric constant (TDC) measurements help assess local skin water to detect incipient early-stage lymphedema subsequent to breast cancer treatment-related lymphedema. However, presurgery measurements are not always obtained and assessments for evolving lymphedema are only made after surgery. Thus, subsequent TDC assessments may be biased in an unknown way dependent on a patient's handedness in relation to the at-risk arm. We investigated this issue by comparing TDC values in dominant and non-dominant volar forearms of 31 left-handed women and 31 right-handed women (age range 24-84 years)...
August 10, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28792959/objective-assessment-of-leg-edema-using-ultrasonography-with-a-gel-pad
#11
Terumi Iuchi, Masato Kobayashi, Sayumi Tsuchiya, Naoki Ohno, Misako Dai, Masaru Matsumoto, Kazuhiro Ogai, Aya Sato, Takuto Sawazaki, Tosiaki Miyati, Shinobu Tanaka, Junko Sugama
Ultrasonography (US) is useful for visual detection of edematous tissues to assess subcutaneous echogenicity. However, visualization of subcutaneous echogenicity is interpreted differently among operators because the evaluation is subjective and individual operators have unique knowledge. This study objectively assessed leg edema using US with a gel pad including fat for normalization of echogenicity in subcutaneous tissue. Five younger adults and four elderly people with leg edema were recruited. We compared assessments of US and limb circumference before and after the intervention of vibration to decrease edema in younger adults, and edema prior to going to sleep and reduced edema in the early morning in elderly people...
2017: PloS One
https://www.readbyqxmd.com/read/28777893/age-related-vascularization-and-ossification-of-joints-in-children-an-international-pilot-study-to-test-multi-observer-ultrasound-reliability
#12
Daniel Windschall, Paz Collado, Jelena Vojinovic, Silvia Magni-Manzoni, Peter Balint, George A W Bruyn, Cristina Hernandez-Diaz, Juan Carlos Nieto, Viviana Ravagnani, Nikolay Tzaribachev, Annamaria Iagnocco, Maria Antonietta D'Agostino, Esperanza Naredo
OBJECTIVE: To determine the intra- and inter-observer reliability of ultrasound (US)-detected age-related joint vascularization and ossification grading in healthy children. METHODS: Following standardized image acquisition and machine setting protocols, 10 international US experts examined four joints (wrist, second metacarpophalangeal joint, knee, and ankle) in 12 healthy children (divided into four age groups: 2-4, 5-8, 9-12, and 13-16 years). Grey-scale was used to detect the ossification grade, and power Doppler (PD) US was used to detect physiological vascularization...
August 4, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28777477/prediction-and-validation-of-dxa-derived-appendicular-fat-free-adipose-tissue-by-a-single-ultrasound-image-of-the-forearm-in-japanese-older-adults
#13
Takashi Abe, Jeremy P Loenneke, Robert S Thiebaud, Eiji Fujita, Takuya Akamine, Mark Loftin
OBJECTIVES: To develop regression-based equations for estimating dual-energy x-ray absorptiometry (DXA) derived appendicular fat-free adipose tissue (FFAT) using a single ultrasound image in the forearm, and to investigate the validity of those equations to calculate FFAT-free appendicular lean mass (aLM-minus-FFATappendicular ) in 311 Japanese adults aged 60 to 79 years. METHODS: Subjects were randomly separated into two groups: 215 in the model-development group (91 men and 124 women) and 96 in the cross-validation group (42 men and 54 women)...
August 4, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28768248/clinical-outcomes-of-dietary-replacement-of-saturated-fatty-acids-with-unsaturated-fat-sources-in-adults-with-overweight-and-obesity-a-systematic-review-and-meta-analysis-of-randomized-control-trials
#14
Bridget A Hannon, Sharon V Thompson, Ruopeng An, Margarita Teran-Garcia
BACKGROUND: Obesity and dyslipidemia are frequently treated with dietary interventions before pharmacotherapy is given. Diets high in unsaturated fat have proven advantageous to disease treatment. AIMS: The purpose of this systematic review and meta-analysis was to assess the evidence of the effect of saturated fatty acids (SFA) replacement with unsaturated fatty acids (UFA) in metabolically healthy adults with overweight and obesity on markers of dyslipidemia and body composition...
2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28761386/effectiveness-of-teaching-facial-anatomy-through-cadaver-dissection-on-aesthetic-physicians-knowledge
#15
Narendra Kumar, Eqram Rahman
BACKGROUND: Cadaver dissection for anatomy training provides an opportunity to understand the precise nature of human tissues with their clinical and structural relationships. This study assessed the effectiveness of this practical educational intervention for teaching applied facial anatomy on the knowledge and confidence of aesthetic physicians. METHODS AND MATERIALS: A total of 168 aesthetic physicians underwent facial applied anatomy training for 2 days at The Academia, Singapore...
2017: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/28759091/fundamentals-for-an-osteopathic-obesity-designed-study-the-effects-of-education-on-osteopathic-medical-students-attitudes-regarding-obesity
#16
Gregory G Gayer, Jennifer Weiss, Michael Clearfield
Context: Obesity is a major health concern in the United States, and its prevalence continues to rise. Although it is a common health issue, many people, including health care professionals, are biased against people with obesity. Objective: To determine whether a comprehensive obesity curriculum presented to students in medical school can positively influence their attitudes toward obesity. Methods: The study was designed around a comprehensive educational obesity curriculum at Touro University College of Osteopathic Medicine-CA, involving the classes of 2013 through 2018...
August 1, 2017: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/28756995/an-investigation-into-the-differences-in-bone-density-and-body-composition-measurements-between-2-ge-lunar-densitometers-and-their-comparison-to-a-4-component-model
#17
Laura P E Watson, Michelle C Venables, Peter R Murgatroyd
We describe a study to assess the precision of the GE Lunar iDXA and the agreement between the iDXA and GE Lunar Prodigy densitometers for the measurement of regional- and total-body bone and body composition in normal to obese healthy adults. We compare the whole-body fat mass by dual-energy X-ray absorptiometry (DXA) to measurements by a 4-component (4-C) model. Sixty-nine participants, aged 37 ± 12 yr, with a body mass index of 26.2 ± 5.1 kg/cm(2), were measured once on the Prodigy and twice on the iDXA...
July 27, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28756299/is-the-size-and-composition-of-the-paraspinal-muscles-associated-with-low-back-pain-a-systematic-review
#18
REVIEW
Tom A Ranger, Flavia M Cicuttini, Tue Secher Jensen, Waruna L Peiris, Sultana Monira Hussain, Jessica Fairley, Donna M Urquhart
Background Context Although previous studies have investigated the association between paraspinal muscle morphology and low back pain (LBP), the results are conflicting. Purpose This systematic review examined the relationship between size and composition of the paraspinal muscles and LBP. Study design/ setting: Systematic review Patient sample: N/A Outcome measures: N/A Methods A systematic search of electronic databases was conducted to identify studies investigating the association between the cross-sectional area and/or fatty infiltration of the paraspinal muscles (erector spinae, multifidus, psoas and quadratus lumborum) and LBP...
July 26, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28749749/estimation-of-resting-energy-expenditure-validation-of-previous-and-new-predictive-equations-in-obese-children-and-adolescents
#19
Nilüfer Acar-Tek, Duygu Ağagündüz, Bülent Çelik, Rukiye Bozbulut
OBJECTIVE: Accurate estimation of resting energy expenditure (REE) in childrenand adolescents is important to establish estimated energy requirements. The aim of the present study was to measure REE in obese children and adolescents by indirect calorimetry method, compare these values with REE values estimated by equations, and develop the most appropriate equation for this group. METHODS: One hundred and three obese children and adolescents (57 males, 46 females) between 7 and 17 years (10...
August 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28747241/developing-a-predictive-model-for-the-energy-content-of-goat-milk-as-the-basis-for-a-functional-unit-formulation-to-be-used-in-the-life-cycle-assessment-of-dairy-goat-production-systems
#20
P P Danieli, B Ronchi
Recent reports on livestock environmental impact based on life cycle assessment (LCA) did not fully consider the case of the dairy goat. Assignment of an environmental impact (e.g. global warming potential) to a specific product needs to be related to the appropriate 'unitary amount' or functional unit (FU). For milk, the energy content may provide a common basis for a definition of the FU. To date, no ad hoc formulations for the FU of goat milk have been proposed. For these reasons, this study aimed to develop and test one or more predictive models (DPMs) for the gross energy (GE) content of goat milk, based on published compositional data, such as fat (F), protein, total solids (TS), solid non-fat matter (SNF), lactose (Lac) and ash...
July 27, 2017: Animal: An International Journal of Animal Bioscience
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