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Obesity bias

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https://www.readbyqxmd.com/read/28822023/pulse-contour-derived-cardiac-output-measurements-in-morbid-obesity-influence-of-actual-ideal-and-adjusted-bodyweight
#1
Chantal A Boly, Pieter Schraverus, Floris van Raalten, Jan-Willem Coumou, Christa Boer, Simone van Kralingen
The non-invasive Nexfin cardiac output (CO) monitor shows a low level of agreement with the gold standard thermodilution method in morbidly obese patients. Here we investigate whether this disagreement is related to excessive bodyweight, and can be improved when bodyweight derivatives are used instead. We performed offline analyses of cardiac output recordings of patient data previously used and partly published in an earlier study by our group. In 30 morbidly obese patients (BMI > 35 kg/m(2)) undergoing laparoscopic gastric bypass, cardiac output was simultaneously determined with PiCCO thermodilution and Nexfin pulse-contour method...
August 18, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28810493/people-with-a-body-mass-index-%C3%A2-30-under-report-their-dietary-intake-a-systematic-review
#2
Helena Wehling, Joanne Lusher
Under-reporting of total energy intake is a common and well-known source of measurement error in dietary assessment, and evidence suggests that this bias is particularly significant in obese individuals. After a multi-stage selection process of eligible papers, this literature review appraised 34 papers detailing the accuracy of self-reported dietary intake in people with an obese body mass index (BMI ⩾ 30). The available literature to date shows that having a body mass index ⩾30 is associated with significant under-reporting of food intake...
July 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28809927/in-middle-aged-and-old-obese-patients-training-intervention-reduces-leptin-level-a-meta-analysis
#3
Ildikó Rostás, László Pótó, Péter Mátrai, Péter Hegyi, Judit Tenk, András Garami, Anita Illés, Margit Solymár, Erika Pétervári, Ákos Szűcs, Andrea Párniczky, Dániel Pécsi, Zoltán Rumbus, Csaba Zsiborás, Nóra Füredi, Márta Balaskó
BACKGROUND: Leptin is one of the major adipokines in obesity that indicates the severity of fat accumulation. It is also an important etiological factor of consequent cardiometabolic and autoimmune disorders. Aging has been demonstrated to aggravate obesity and to induce leptin resistance and hyperleptinemia. Hyperleptinemia, on the other hand, may promote the development of age-related abnormalities. While major weight loss has been demonstrated to ameliorate hyperleptinemia, obese people show a poor tendency to achieve lasting success in this field...
2017: PloS One
https://www.readbyqxmd.com/read/28791776/low-validity-of-predictive-equations-for-calculating-resting-energy-expenditure-in-overweight-and-obese-women-with-polycystic-ovary-syndrome
#4
A M Dos S Rodrigues, A B P Costa, D L Campos, M P S Silva, A L Cândido, L C Dos Santos, A V M Ferreira
BACKGROUND: Predictive equations are the main clinical tools for determining resting energy expenditure (REE). However, their adequate use in overweight and obese individuals is unclear. Thus, we investigated the best predictive equations for estimating REE in overweight and obese women with polycystic ovary syndrome (PCOS). METHODS: Eleven analyses were performed with prediction equations (pREE) based on anthropometric parameters in 30 overweight or obese women with PCOS without other chronic diseases...
August 8, 2017: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/28790228/association-between-serum-uric-acid-and-non-alcoholic-fatty-liver-disease-a-meta-analysis
#5
Guntur Darmawan, Laniyati Hamijoyo, Irsan Hasan
BACKGROUND: non-alcoholic fatty liver disease (NAFLD) is known to be associated with some metabolic disorders. Recent studies suggested the role of uric acid in NAFLD through oxidative stress and inflammatory process. This study is aimed to evaluate the association between serum uric acid and NAFLD. METHODS: a systematic literature review was conducted using Pubmed and Cochrane library. The quality of all studies was assessed using the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE)...
April 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/28789665/evaluating-the-evidence-for-macrophage-presence-in-skeletal-muscle-and-its-relation-to-insulin-resistance-in-obese-mice-and-humans-a-systematic-review-protocol
#6
Meha Bhatt, Srikesh Rudrapatna, Laura Banfield, Rachel Bierbrier, Pei-Wen Wang, Kuan-Wen Wang, Lehana Thabane, M Constantine Samaan
OBJECTIVES: The current global rates of obesity and type 2 diabetes are staggering. In order to implement effective management strategies, it is imperative to understand the mechanisms of obesity-induced insulin resistance and diabetes. Macrophage infiltration and inflammation of the adipose tissue in obesity is a well-established paradigm, yet the role of macrophages in muscle inflammation, insulin resistance and diabetes is not adequately studied. In this systematic review, we will examine the evidence for the presence of macrophages in skeletal muscle of obese humans and mice, and will assess the association between muscle macrophages and insulin resistance...
August 8, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28780991/a-simple-method-for-identification-of-misreporting-of-energy-intake-from-infancy-to-school-age-results-from-a-longitudinal-study
#7
Delphina Gomes, Veronica Luque, Annick Xhonneux, Elvira Verduci, Piotr Socha, Berthold Koletzko, Ursula Berger, Veit Grote
BACKGROUND & AIMS: Misreporting is a major source of reporting bias in nutritional surveys. It can affect the analysis of associations between diet and disease. Although various methods have been proposed to identify misreporting, their application to infants and young children is difficult. We identify misreporting of energy intake in infants and young children and propose a simplified approach. METHODS: 1199 children were enrolled in the Childhood Obesity Programme (CHOP) based in 5 European countries (Belgium, Germany, Italy, Poland and Spain) with repeated measurements of 3-day weighed food protocol and anthropometric indices at 10 time points between ages 1-96 months...
June 1, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28768248/clinical-outcomes-of-dietary-replacement-of-saturated-fatty-acids-with-unsaturated-fat-sources-in-adults-with-overweight-and-obesity-a-systematic-review-and-meta-analysis-of-randomized-control-trials
#8
Bridget A Hannon, Sharon V Thompson, Ruopeng An, Margarita Teran-Garcia
BACKGROUND: Obesity and dyslipidemia are frequently treated with dietary interventions before pharmacotherapy is given. Diets high in unsaturated fat have proven advantageous to disease treatment. AIMS: The purpose of this systematic review and meta-analysis was to assess the evidence of the effect of saturated fatty acids (SFA) replacement with unsaturated fatty acids (UFA) in metabolically healthy adults with overweight and obesity on markers of dyslipidemia and body composition...
July 29, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28767639/inaccuracies-in-icd-coding-for-obesity-would-be-expected-to-bias-administrative-database-spine-studies-toward-overestimating-the-impact-of-obesity-on-perioperative-adverse-outcomes
#9
Ryan P McLynn, Benjamin J Geddes, Jonathan J Cui, Nathaniel T Ondeck, Patawut Bovonratwet, Blake N Shultz, Jonathan N Grauer
STUDY DESIGN: Retrospective cohort study OBJECTIVE.: To determine if International Classification of Diseases (ICD) coding for obesity is biased toward certain subgroups and how potential bias may influence the outcomes of database research in spine. SUMMARY OF BACKGROUND DATA: There has been increased use of national databases using administrative data in the spine surgery literature. Past research demonstrates that sensitivity of ICD codes for obesity is poor, but it is unknown if such inaccuracies are systematically biased and if they may bias studies utilizing such data...
August 1, 2017: Spine
https://www.readbyqxmd.com/read/28767517/accuracy-of-self-reported-weight-in-hispanic-latino-adults-of-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#10
Lindsay Fernández-Rhodes, Whitney R Robinson, Daniela Sotres-Alvarez, Nora Franceschini, Sheila F Castañeda, Christina Buelna, Ashley Moncrieft, Maria Llabre, Martha L Daviglus, Qibin Qi, Anita Agarwal, Carmen R Isasi, Paul Smokowski, Penny Gordon-Larsen, Kari E North
BACKGROUND: Previous United States (U.S.) population-based studies have found that body weight may be underestimated when self-reported. However, this research may not apply to all U.S. Hispanics/Latinos, many of whom are immigrants with distinct cultural orientations to ideal body size. We assessed the data quality and accuracy of self-reported weight in a diverse, community-based, U.S. sample of primarily foreign-born Hispanic/Latino adults. METHODS: Using baseline data (2008-2011) from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), we described the difference between contemporaneous self-reported and measured current body weight (n=16,119) and used multivariate adjusted models to establish whether the observed trends in misreporting in potential predictors of inaccuracy persisted after adjustment for other predictors...
July 31, 2017: Epidemiology
https://www.readbyqxmd.com/read/28763444/childhood-adiposity-and-risk-of-type-1-diabetes-a-mendelian-randomization-study
#11
J C Censin, Christoph Nowak, Nicholas Cooper, Peter Bergsten, John A Todd, Tove Fall
BACKGROUND: The incidence of type 1 diabetes (T1D) is increasing globally. One hypothesis is that increasing childhood obesity rates may explain part of this increase, but, as T1D is rare, intervention studies are challenging to perform. The aim of this study was to assess this hypothesis with a Mendelian randomization approach that uses genetic variants as instrumental variables to test for causal associations. METHODS AND FINDINGS: We created a genetic instrument of 23 single nucleotide polymorphisms (SNPs) associated with childhood adiposity in children aged 2-10 years...
August 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28761927/body-mass-index-in-midlife-and-dementia-systematic-review-and-meta-regression-analysis-of-589-649-men-and-women-followed-in-longitudinal-studies
#12
REVIEW
Emiliano Albanese, Lenore J Launer, Matthias Egger, Martin J Prince, Panteleimon Giannakopoulos, Frank J Wolters, Kieren Egan
INTRODUCTION: We conducted a meta-analysis of the conflicting epidemiologic evidence on the association between midlife body mass index (BMI) and dementia. METHODS: We searched standard databases to identify prospective, population-based studies of dementia risk by midlife underweight, overweight, and obesity. We performed random-effects meta-analyses and meta-regressions of adjusted relative risk (RR) estimates and formally explored between-study heterogeneity...
2017: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
https://www.readbyqxmd.com/read/28761689/efficacy-of-dietary-and-physical-activity-intervention-in-non-alcoholic-fatty-liver-disease-a-systematic-review
#13
Susan Kenneally, Joanna H Sier, J Bernadette Moore
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide, with prevalence above 30% in many adult populations. Strongly associated with obesity, weight loss through diet and physical activity is the mainstay of its management. Weight loss can be difficult to achieve and maintain however, and uncertainty exists as to which lifestyle changes are most effective. OBJECTIVE: The aim of this work was to systematically evaluate randomised controlled trials assessing diet, exercise or combination interventions aimed at reducing steatosis or markers of NAFLD activity...
2017: BMJ Open Gastroenterology
https://www.readbyqxmd.com/read/28759091/fundamentals-for-an-osteopathic-obesity-designed-study-the-effects-of-education-on-osteopathic-medical-students-attitudes-regarding-obesity
#14
Gregory G Gayer, Jennifer Weiss, Michael Clearfield
Context: Obesity is a major health concern in the United States, and its prevalence continues to rise. Although it is a common health issue, many people, including health care professionals, are biased against people with obesity. Objective: To determine whether a comprehensive obesity curriculum presented to students in medical school can positively influence their attitudes toward obesity. Methods: The study was designed around a comprehensive educational obesity curriculum at Touro University College of Osteopathic Medicine-CA, involving the classes of 2013 through 2018...
August 1, 2017: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/28758096/type-2-diabetes-mellitus-and-risk-of-hepatocellular-carcinoma-spotlight-on-nonalcoholic-fatty-liver-disease
#15
REVIEW
Alessandro Mantovani, Giovanni Targher
The incidence of both type 2 diabetes mellitus (T2DM) and multiple cancer types are rapidly increasing worldwide. Several studies documented that T2DM is closely associated with an increased incidence of cancer. However, while some methodological considerations preclude a definitive association between T2DM and the risk of certain cancers, the relationship between T2DM and increased risk of incident hepatocellular carcinoma (HCC) remains significant even after adjustment for detection bias and reverse causation, indicating that such association is clinically reliable and robust...
July 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28756995/an-investigation-into-the-differences-in-bone-density-and-body-composition-measurements-between-2-ge-lunar-densitometers-and-their-comparison-to-a-4-component-model
#16
Laura P E Watson, Michelle C Venables, Peter R Murgatroyd
We describe a study to assess the precision of the GE Lunar iDXA and the agreement between the iDXA and GE Lunar Prodigy densitometers for the measurement of regional- and total-body bone and body composition in normal to obese healthy adults. We compare the whole-body fat mass by dual-energy X-ray absorptiometry (DXA) to measurements by a 4-component (4-C) model. Sixty-nine participants, aged 37 ± 12 yr, with a body mass index of 26.2 ± 5.1 kg/cm(2), were measured once on the Prodigy and twice on the iDXA...
July 27, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28749749/estimation-of-resting-energy-expenditure-validation-of-previous-and-new-predictive-equations-in-obese-children-and-adolescents
#17
Nilüfer Acar-Tek, Duygu Ağagündüz, Bülent Çelik, Rukiye Bozbulut
OBJECTIVE: Accurate estimation of resting energy expenditure (REE) in childrenand adolescents is important to establish estimated energy requirements. The aim of the present study was to measure REE in obese children and adolescents by indirect calorimetry method, compare these values with REE values estimated by equations, and develop the most appropriate equation for this group. METHODS: One hundred and three obese children and adolescents (57 males, 46 females) between 7 and 17 years (10...
August 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28743256/a-comparison-of-multiple-imputation-methods-for-handling-missing-values-in-longitudinal-data-in-the-presence-of-a-time-varying-covariate-with-a-non-linear-association-with-time-a-simulation-study
#18
Anurika Priyanjali De Silva, Margarita Moreno-Betancur, Alysha Madhu De Livera, Katherine Jane Lee, Julie Anne Simpson
BACKGROUND: Missing data is a common problem in epidemiological studies, and is particularly prominent in longitudinal data, which involve multiple waves of data collection. Traditional multiple imputation (MI) methods (fully conditional specification (FCS) and multivariate normal imputation (MVNI)) treat repeated measurements of the same time-dependent variable as just another 'distinct' variable for imputation and therefore do not make the most of the longitudinal structure of the data...
July 25, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28743192/searching-for-evidence-of-an-anti-inflammatory-diet-in-children-a-systematic-review-of-randomized-controlled-trials-for-pediatric-obesity-interventions-with-a-focus-on-leptin-ghrelin-and-adiponectin
#19
Kimberly A Lewis, Sharon A Brown
PROBLEM: To address the complex phenomenon of pediatric obesity, one must understand the physiological mechanisms regulating energy intake and inflammation. The peptide hormones leptin, ghrelin, and adiponectin are involved in both, but their functions are dysregulated in obesity. The purpose of this systematic review is (1) to characterize studies of nutrition interventions for weight management in children who measure these peptides as outcomes, (2) to assess risk of bias in the studies, and (3) to determine the relationships between these peptides and body mass index (BMI)...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28742946/the-association-between-obesity-and-academic-performance-in-youth-a-systematic-review
#20
REVIEW
C C A Santana, J O Hill, L B Azevedo, T Gunnarsdottir, W L Prado
Previous studies have found that obesity could influence academic performance. The aim of this study was to systematically review the scientific evidence on the association between obesity and academic performance in school children. A systematic review of English articles was undertaken by using databases PubMed/Medline, ERIC, LILACS, SciELO and Web of Science. Cross-sectional and longitudinal studies examining the association between obesity and academic performance in children and adolescents, published between January 1990 and December 2016, were included...
July 25, 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
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