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https://www.readbyqxmd.com/read/29338176/polystyrene-block-poly-ionic-liquid-copolymers-as-work-function-modifiers-in-inverted-organic-photovoltaic-cells
#1
Jong Baek Park, Mehmet Isik, Hea Jung Park, In Hwan Jung, David Mecerreyes, Do-Hoon Hwang
Interfacial layers play a critical role in building up the ohmic contact between the electrodes and functional layers in organic photovoltaic solar cells. These layers are based on either inorganic oxides (ZnO, TiO2) or water-soluble organic polymers such as poly[(9,9-dioctyl-2,7-fluorene)-alt-(9,9-bis(3'-(N,N-dimethylamino)propyl)-2,7-fluorene)] (PFN) and polyethylenimine ethoxylated (PEIE). In this work, we have developed a series of novel poly(ionic liquid) non-conjugated block copolymers for improving the performance of inverted organic photovoltaic cells (OPVs) by acting as work function modifiers of indium tin oxide (ITO) cathode...
January 17, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29324447/characteristic-motor-and-nonmotor-symptoms-related-to-quality-of-life-in-drug-na%C3%A3-ve-patients-with-late-onset-parkinson-disease
#2
Hea Ree Park, Jinyoung Youn, Jin Whan Cho, Eung-Seok Oh, Ji Sun Kim, Suyeon Park, Wooyoung Jang, Jin Se Park
BACKGROUND/AIMS: Unlike young-onset Parkinson disease (YOPD), characteristics of late-onset PD (LOPD) have not yet been clearly elucidated. We investigated characteristic features and symptoms related to quality of life (QoL) in LOPD patients. METHODS: We recruited drug-naïve, early PD patients. The patient cohort was divided into 3 subgroups based on patient age at onset (AAO): the YOPD group (AAO <50 years), the middle-onset PD (MOPD) group, and the LOPD group (AAO ≥70 years)...
January 12, 2018: Neuro-degenerative Diseases
https://www.readbyqxmd.com/read/29321963/a-critical-role-of-hepatitis-b-virus-polymerase-in-cirrhosis-hepatocellular-carcinoma-and-steatosis
#3
Hea-Jong Chung, Xiao Chen, Yang Yu, Heui-Kwan Lee, Chang Ho Song, Han Choe, Seungkoo Lee, Hyeon-Jin Kim, Seong-Tshool Hong
Hepatitis B is one of the most common infectious diseases in the world; more than 350 million people are carriers of hepatitis B virus (HBV). Chronic HBV infection (CHB) leads to liver diseases such as cirrhosis, hepatocellular carcinoma (HCC), and steatosis. Despite its seriousness in terms of public health, the pathogenic mechanism of how CHB leads to liver diseases, especially cirrhosis and steatosis, remains unclear. We studied the role of HBV polymerase (HBp) reverse transcriptase (RT) activity in association with the pathogenesis of liver diseases in CHB by developing transgenic mice expressing HBp or the RT domain of HBp...
January 2018: FEBS Open Bio
https://www.readbyqxmd.com/read/29318249/preparing-bulk-ultrafine-microstructure-high-entropy-alloys-via-direct-solidification
#4
Yiping Lu, Xiaoxia Gao, Yong Dong, Tongmin Wang, Hai-Lin Chen, Huahai Maob, Yonghao Zhao, Hui Jiang, Zhiqiang Cao, Tingju Li, Sheng Guo
In the past three decades, nanostructured (NS) and ultrafine-microstructure (UFM) materials have received extensive attention due to their excellent mechanical properties such as high strength. However, preparing low-cost and bulk NS and UFM materials remains to be a challenge, which limits their industrial applications. Here, we report a new strategy to prepare bulk UFM alloys via the direct solidification of high-entropy alloys (HEAs). As a proof of concept, we designed AlCoCrxFeNi (1.8 ≤ x ≤ 2.0) HEAs and achieved a complete UFM in bulk materials...
January 10, 2018: Nanoscale
https://www.readbyqxmd.com/read/29299898/a-case-of-community-acquired-pneumonia-caused-by-multidrug-resistant-acinetobacter-baumannii-in-korea
#5
Young Woong Son, In Young Jung, Mi Young Ahn, Yong Duk Jeon, Hea Won Ann, Jin Young Ahn, Nam Su Ku, Sang Hoon Han, Jun Young Choi, Young Goo Song, June Myung Kim
Acinetobacter baumannii is an aerobic Gram-negative coccobacillus that causes nosocomial pneumonia in patients on mechanical ventilation or previously treated with broad-spectrum antibiotics. Nevertheless, community-acquired pneumonia (CAP) caused by A. baumannii, especially multi-drug resistant (MDR) strains, is rare. We experienced the first case of CAP caused by MDR A. baumannii in Korea in a 78-year-old man. This case shows that MDR A. baumannii can cause CAP in Korea.
December 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29286442/neurobehavioral-assessments-in-a-mouse-model-of-neonatal-hypoxic-ischemic-brain-injury
#6
MinGi Kim, Ji Hea Yu, Jung Hwa Seo, Yoon-Kyum Shin, Soohyun Wi, Ahreum Baek, Suk-Young Song, Sung-Rae Cho
We performed unilateral carotid artery occlusion on CD-1 mice to create a neonatal hypoxic-ischemic (HI) model and investigated the effects of neonatal HI brain injury by studying neurobehavioral functions in these mice compared to non-operated (i.e., normal) mice. During the study, Rice-Vannucci's method was used to induce neonatal HI brain damage in postnatal day 7-10 (P7-10) mice. The HI operation was performed on the pups by unilateral carotid artery ligation and exposure to hypoxia (8% O2 and 92% N2 for 90 min)...
November 24, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29276524/molecular-mapping-of-pmr1-a-novel-locus-conferring-resistance-to-powdery-mildew-in-pepper-capsicum-annuum
#7
Jinkwan Jo, Jelli Venkatesh, Koeun Han, Hea-Young Lee, Gyung Ja Choi, Hee Jae Lee, Doil Choi, Byoung-Cheorl Kang
Powdery mildew, caused by Leveillula taurica, is a major fungal disease affecting greenhouse-grown pepper (Capsicum annuum). Powdery mildew resistance has a complex mode of inheritance. In the present study, we investigated a novel powdery mildew resistance locus, PMR1, using two mapping populations: 102 'VK515' F2:3 families (derived from a cross between resistant parental line 'VK515R' and susceptible parental line 'VK515S') and 80 'PM Singang' F2 plants (derived from the F1 'PM Singang' commercial hybrid)...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29261675/the-limited-prognostic-role-of-echocardiograms-in-short-term-follow-up-after-acute-decompensated-heart-failure-an-analysis-of-the-korean-heart-failure-korhf-registry
#8
Sung Hea Kim, Hyun-Joong Kim, Seongwoo Han, Byung-Su Yoo, Dong-Ju Choi, Jae-Joong Kim, Eun-Seok Jeon, Myeong-Chan Cho, Shung Chull Chae, Kyu-Hyung Ryu
BACKGROUND: The prognostic values of the left ventricular ejection fraction (LVEF) and end-diastolic dimension (LVEDD) have primarily been shown among patients with chronic heart failure (HF), with little representation of patients with acute HF (AHF). Therefore, we investigated the value of these echocardiographic parameters in predicting clinical outcomes among patients in the Korean Heart Failure (KorHF) Registry. METHODS: The KorHF Registry consists of 3,200 patients who were hospitalized with AHF from 2005 to 2009...
2017: PloS One
https://www.readbyqxmd.com/read/29248767/efficient-purification-of-apolipoprotein-a1-apoa1-from-plasma-by-hea-hypercel%C3%A2-an-alternative-approach
#9
Arun Govind G, Agamudi Shivasankaran Kamalanathan, Mookambeswaran Arunachalam Vijayalakshmi, Krishnan Venkataraman
HDL-ApoA1 plays a pivotal role in the prevention of atherosclerosis and cardiovascular diseases. ApoA1 purification from blood plasma has always remained tedious, involving multiple steps, large volumes of plasma and substantial loss in the final yield of pure ApoA1. In this study, a two-step method has been developed and optimized for the purification of ApoA1 from plasma. Plasma was first subjected to 60% ammonium sulphate (NH4)2SO4 precipitation and subsequently, ApoA1 was recovered using mixed mode chromatographic sorbent, HEA HyperCel™...
December 11, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29237253/combination-of-carboplatin-and-intermittent-normobaric-hyperoxia-synergistically-suppresses-benzo-a-pyrene-induced-lung-cancer
#10
Hea Yon Lee, In Kyoung Kim, Hye In Lee, Hwa Young Lee, Hye Seon Kang, Chang Dong Yeo, Hyun Hui Kang, Hwa Sik Moon, Sang Haak Lee
Background/Aims: We explored the effects of intermittent normobaric hyperoxia alone or combined with chemotherapy on the growth, general morphology, oxidative stress, and apoptosis of benzo[a]pyrene (B[a]P)-induced lung tumors in mice. Methods: Female A/J mice were given a single dose of B[a]P and randomized into four groups: control, carboplatin (50 mg/kg intraperitoneally), hyperoxia (95% fraction of inspired oxygen), and carboplatin and hyperoxia. Normobaric hyperoxia (95%) was applied for 3 hours each day from weeks 21 to 28...
December 15, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29233710/magnetic-field-driven-drug-release-from-modified-iron-oxide-integrated-polysaccharide-hydrogel
#11
Xinyu Hu, Yongmei Wang, Liangliang Zhang, Man Xu, Jianfa Zhang, Wei Dong
Salecan is a novel water-soluble extracellular β-glucan and suitable for the hydrogel preparation due to its excellent physicochemical and biological properties. The present article describes the fabrication and characterization of a pH/magnetic field-driven hydrogel based on salecan-g-poly(vinylacetic acid-co-2-hydroxyethyl acrylate) [poly(VA-co-HEA)] copolymer and Fe3O4@Agarose nanoparticles for drug release testing. Vibrating sample magnetometer characterization verified that integration of Fe3O4@Agarose nanoparticles in the copolymer provided the sensitivity to magnetic fields...
December 9, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29231316/-resuscitation-acupuncture-for-thalamic-pain-a-randomized-controlled-trial
#12
Yajie Li, Hao Tian, Li An, Xuemin Shi
OBJECTIVE: To compare the effects between resuscitation acupuncture and pregabalin for thalamic pain and their impacts on plasma P substance (SP) and β-endorphin (β-EP). METHODS: Sixty-four patients were randomly assigned into an acupuncture group and a western medication group, 32 cases in each one. Based on conventional western methods, pregabalin capsule was used orally in the western medication group, 75 mg a time,twice a day; resuscitation acupuncture was applied in the acupuncture group...
January 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29209463/eating-patterns-of-children-s-favorite-foods-and-its-related-factors-among-elementary-middle-and-high-school-students-in-korea
#13
YuJin Lee, Seungmin Lee, KyoungAe Lee, Kyung-Hea Lee, Inkyung Baik
BACKGROUND/OBJECTIVES: There are limited studies investigating the eating patterns of children's favorite foods. The present study aimed to evaluate a wide range of children's favorite foods, derive its eating patterns, and identify factors related to the patterns. SUBJECTS/METHODS: A nationwide cross-sectional study included 5,458 students in elementary, middle, and high schools. The survey was conducted at each school to evaluate children's favorite food intake, including the intake frequency of 31 food items or food groups, and its related factors, such as demographic, economic, and environmental characteristics and awareness of policies on children's favorite foods...
December 2017: Nutrition Research and Practice
https://www.readbyqxmd.com/read/29177119/diversity-of-bacterial-communities-on-the-facial-skin-of-different-age-group-thai-males
#14
Alisa Wilantho, Pamornya Deekaew, Chutika Srisuttiyakorn, Sissades Tongsima, Naraporn Somboonna
Background: Skin microbiome varies from person to person due to a combination of various factors, including age, biogeography, sex, cosmetics and genetics. Many skin disorders appear to be related to the resident microflora, yet databases of facial skin microbiome of many biogeographies, including Thai, are limited. Methods: Metagenomics derived B-RISA and 16S rRNA gene sequencing was utilized to identify the culture-independent bacterial diversity on Thai male faces (cheek and forehead areas)...
2017: PeerJ
https://www.readbyqxmd.com/read/29170444/enhanced-strength-and-ductility-in-a-friction-stir-processing-engineered-dual-phase-high-entropy-alloy
#15
S S Nene, K Liu, M Frank, R S Mishra, R E Brennan, K C Cho, Z Li, D Raabe
The potential of high-entropy alloys (HEAs) to exhibit an extraordinary combination of properties by shifting the compositional regime from the corners towards the centers of phase diagrams has led to worldwide attention by material scientists. Here we present a strong and ductile non-equiatomic HEA obtained after friction stir processing (FSP). A transformation-induced plasticity (TRIP) assisted HEA with composition Fe50Mn30Co10Cr10 (at.%) was severely deformed by FSP and evaluated for its microstructure-mechanical property relationship...
November 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29151618/heterofunctional-poly-ethylene-glycol-peg-macroinitiator-enabling-controlled-synthesis-of-abc-triblock-copolymers
#16
Lies A L Fliervoet, Marzieh Najafi, Mathew Hembury, Tina Vermonden
ABC triblock copolymers with a poly(ethylene glycol) (PEG) midblock have attractive properties for biomedical applications because of PEG's favorable properties regarding biocompatibility and hydrophilicity. However, easy strategies to synthesize polymers containing a PEG midblock are limited. In this study, the successful synthesis of a heterofunctional PEG macroinitiator containing both an azoinitiator and an atom transfer radical polymerization (ATRP) initiator is demonstrated. This novel PEG macroinitiator allows the development of elegant synthesis routes for PEG midblock-containing ABC copolymers that does not require protection of initiating sites or polymer end-group postmodification...
November 14, 2017: Macromolecules
https://www.readbyqxmd.com/read/29143853/sex-specific-risk-assessment-of-pfhxs-using-a-physiologically-based-pharmacokinetic-model
#17
Sook-Jin Kim, Hwajin Shin, Yong-Bok Lee, Hea-Young Cho
Perfluorohexanesulfonate (PFHxS), which belongs to the group of perfluoroalkyl and polyfluoroalkyl substances (PFASs), has been extensively used in industry and subsequently detected in the environment. Its use may be problematic, as PFHxS is known to induce neuronal cell death, and has been associated with early onset menopause in women and with attention deficit/hyperactivity disorder. Due to these impending issues, the aim of this study is to develop and evaluate a physiologically based pharmacokinetic (PBPK) model for PFHxS in male and female rats, and apply this to a human health risk assessment...
November 16, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/29137749/exceptionally-high-cavitation-erosion-and-corrosion-resistance-of-a-high-entropy-alloy
#18
R B Nair, H S Arora, Sundeep Mukherjee, S Singh, H Singh, H S Grewal
Cavitation erosion and corrosion of structural materials are serious concerns for marine and offshore industries. Durability and performance of marine components are severely impaired due to degradation from erosion and corrosion. Utilization of advanced structural materials can play a vital role in limiting such degradation. High entropy alloys (HEAs) are a relatively new class of advanced structural materials with exceptional properties. In the present work, we report on the cavitation erosion behavior of Al0...
March 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/29137619/percutaneous-medial-hemi-epiphysiodesis-using-a-transphyseal-screw-for-caput-valgum-associated-with-developmental-dysplasia-of-the-hip
#19
Chang Ho Shin, Wan Kee Hong, Doo Jae Lee, Won Joon Yoo, In Ho Choi, Tae-Joon Cho
BACKGROUND: The purpose of this study was to evaluate the radiologic outcome of percutaneous medial hemi-epiphysiodesis using a transphyseal screw for the management of caput valgum associated with developmental dysplasia of the hip (DDH). METHODS: Eighteen hips (18 patients) having caput valgum treated with screw hemi-epiphysiodesis were followed for more than 2 years, and were included in this study. The mean age at the time of the index operation was 8.3 years (range, 4...
November 14, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29122239/early-warning-of-limit-exceeding-concentrations-of-cyanobacteria-and-cyanotoxins-in-drinking-water-reservoirs-by-inferential-modelling
#20
Friedrich Recknagel, Philip T Orr, Michael Bartkow, Annelie Swanepoel, Hongqing Cao
An early warning scheme is proposed that runs ensembles of inferential models for predicting the cyanobacterial population dynamics and cyanotoxin concentrations in drinking water reservoirs on a diel basis driven by in situ sonde water quality data. When the 10- to 30-day-ahead predicted concentrations of cyanobacteria cells or cyanotoxins exceed pre-defined limit values, an early warning automatically activates an action plan considering in-lake control, e.g. intermittent mixing and ad hoc water treatment in water works, respectively...
November 2017: Harmful Algae
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