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https://www.readbyqxmd.com/read/28820759/thromboprophylaxis-in-spinal-surgery
#1
William P Mosenthal, David C Landy, Haroutioun H Boyajian, Olumuyiwa A Idowu, Lewis L Shi, Edwin Ramos, Michael J Lee
STUDY DESIGN: Systematic review and meta-analysis OBJECTIVE.: Determine the incidence of deep vein thrombosis (DVT) and pulmonary embolism (PE) in spinal surgery patients receiving no thromboprophylaxis, mechanoprophylaxis, and chemoprophylaxis. SUMMARY OF BACKGROUND DATA: The incidence of thromboembolic complications after spinal surgery is not well established. While a variety of effective mechanical and chemical thromboprophylaxis interventions exist, their role in spinal surgery remains unclear...
August 17, 2017: Spine
https://www.readbyqxmd.com/read/28819870/surgical-complications-of-extraspinal-tumors-in-the-cervical-spine-a-report-of-110-cases-and-literature-review
#2
WenHua Yang, Liang Jiang, XiaoGuang Liu, Feng Wei, Miao Yu, FengLiang Wu, Lei Dang, Hua Zhou, Hua Zhang, ZhongJun Liu
PURPOSE: To assess the safety of surgical intervention for extraspinal tumors in the cervical spine. METHODS: 110 consecutive patients were enrolled and followed-up at least 12 months or until death. The complication rates and risk factors were documented and analyzed. RESULTS: The quality of life in the surviving patients was significantly improved. The overall local recurrence rate was 17.3%. Twenty percent of patients developed distant metastasis...
August 17, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28819125/inflammation-and-bone-mineral-density-a-mendelian-randomization-study
#3
Jian V Huang, C Mary Schooling
Osteoporosis is a common age-related disorder leading to an increase in osteoporotic fractures and resulting in significant suffering and disability. Inflammation may contribute to osteoporosis, as it does to many other chronic diseases. We examined whether inflammation is etiologically relevant to osteoporosis, assessed from bone mineral density (BMD), as a new potential target of intervention, or whether it is a symptom/biomarker of osteoporosis. We obtained genetic predictors of inflammatory markers from genome-wide association studies and applied them to a large genome wide association study of BMD...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28816874/does-surgical-intervention-or-timing-of-surgery-have-an-effect-on-neurological-recovery-in-the-setting-of-a-thoracolumbar-burst-fracture
#4
So Kato, Jean-Christophe Murray, Brian K Kwon, Gregory D Schroeder, Alexander R Vaccaro, Michael G Fehlings
Traumatic thoracolumbar burst fractures are one of the most common forms of spinal trauma with the majority occurring at the junctional area where mechanical load is maximal (AOSpine Thoracolumbar Spine Injury Classification System Subtype A3 or A4). Burst fractures entail the involvement of the middle column, and therefore, they are typically associated with bone fragment in the spinal canal, which may cause compression of the spinal cord, conus medullaris, cauda equina, or a combination of these. Fortunately, approximately half of the patients with thoracolumbar burst fractures are neurologically intact due to the wide canal diameter...
September 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28816869/spine-trauma-what-are-the-current-controversies
#5
Cumhur Oner, Shanmuganathan Rajasekaran, Jens R Chapman, Michael G Fehlings, Alexander R Vaccaro, Gregory D Schroeder, Said Sadiqi, James Harrop
Although less common than other musculoskeletal injuries, spinal trauma may lead to significantly more disability and costs. During the last 2 decades there was substantial improvement in our understanding of the basic patterns of spinal fractures leading to more reliable classification and injury severity assessment systems but also rapid developments in surgical techniques. Despite these advancements, there remain unresolved issues concerning the management of these injuries. At this moment there is persistent controversy within the spinal trauma community, which can be grouped under 6 headings...
September 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28816825/is-two-level-cervical-disc-replacement-more-cost-effective-than-anterior-cervical-discectomy-and-fusion-at-7-years
#6
Robert K Merrill, Steven J McAnany, Todd J Albert, Sheeraz A Qureshi
STUDY DESIGN: Cost-effectiveness analysis. OBJECTIVE: Investigate the 7-year cost-effectiveness of two-level cervical disc replacement (CDR) and anterior cervical discectomy and fusion (ACDF). SUMMARY OF BACKGROUND DATA: CDR and ACDF are both effective treatment strategies for managing degenerative conditions of the cervical spine. CDR has been shown to be a more-cost effective intervention in the short term, but the long-term cost-effectiveness has not been established...
August 14, 2017: Spine
https://www.readbyqxmd.com/read/28815160/the-burden-of-spine-fractures-in-india-a-prospective-multicenter-study
#7
Ilyas S Aleem, Dylan DeMarco, Brian Drew, Parag Sancheti, Vijay Shetty, Mandeep Dhillon, Clary J Foote, Mohit Bhandari
STUDY DESIGN: Prospective cohort study. OBJECTIVES: The objectives of this study were (1) to determine the characteristics of patients sustaining spinal trauma in India and (2) to explore the association between patient or injury characteristics and outcomes after spinal trauma. METHODS: In affiliation with the ongoing INternational ORthopaedic MUlticentre Study (INORMUS), 192 patients with spinal injuries were recruited during an 8-week period (November 2011 to June 2012) from 14 hospitals in India and followed for 30-days...
June 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28811991/systematic-review-of-the-outcomes-of-surgical-treatment-of-prostate-metastases-to-the-spine
#8
REVIEW
Michelle J Clarke, Camilo A Molina, Daryl R Fourney, Charles G Fisher, Ziya L Gokaslan, Meic H Schmidt, Laurence D Rhines, Michael G Fehlings, Ilya Laufer, Shreyaskumar R Patel, Y Raja Rampersaud, Jeremy Reynolds, Dean Chou, Chetan Bettegowda, Ehud Mendel, Michael H Weber, Daniel M Sciubba
STUDY DESIGN: Systematic review. OBJECTIVE: Surgical decompression and reconstruction of symptomatic spinal metastases has improved the quality of life in cancer patients. However, most data has been collected on cohorts of patients with mixed tumor histopathology. We systematically reviewed the literature for prognostic factors specific to the surgical treatment of prostate metastases to the spine. METHODS: A systemic review of the literature was conducted to answer the following questions: Question 1...
August 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28808792/using-natural-language-processing-of-free-text-radiology-reports-to-identify-type-1-modic-endplate-changes
#9
Hannu T Huhdanpaa, W Katherine Tan, Sean D Rundell, Pradeep Suri, Falgun H Chokshi, Bryan A Comstock, Patrick J Heagerty, Kathryn T James, Andrew L Avins, Srdjan S Nedeljkovic, David R Nerenz, David F Kallmes, Patrick H Luetmer, Karen J Sherman, Nancy L Organ, Brent Griffith, Curtis P Langlotz, David Carrell, Saeed Hassanpour, Jeffrey G Jarvik
Electronic medical record (EMR) systems provide easy access to radiology reports and offer great potential to support quality improvement efforts and clinical research. Harnessing the full potential of the EMR requires scalable approaches such as natural language processing (NLP) to convert text into variables used for evaluation or analysis. Our goal was to determine the feasibility of using NLP to identify patients with Type 1 Modic endplate changes using clinical reports of magnetic resonance (MR) imaging examinations of the spine...
August 14, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28807431/a-prospective-analysis-of-injury-rates-patterns-and-causes-in-cliff-and-splash-diving
#10
Lukas Ernstbrunner, Armin Runer, Paul Siegert, Matthäus Ernstbrunner, Johannes Becker, Thomas Freude, Herbert Resch, Philipp Moroder
INTRODUCTION: Information about injuries and its differences in Cliff Diving (CD) and Splash Diving (SD) are unknown. It was the aim to analyse (1) injury rates, patterns and causes; (2) differences (in injuries) between both disciplines; and to (3) identify targets for future injury prevention interventions. METHODS: From April to November 2013, 81 cliff and 51 splash divers were prospectively surveyed with an encrypted, monthly e-mail-based questionnaire. RESULTS: During a total of 7857h diving with an average diving height of 13 (±7)m, an overall injury rate of 7...
August 5, 2017: Injury
https://www.readbyqxmd.com/read/28799855/surgical-management-of-cervical-spine-deformity-in-chondrodysplasia-punctata
#11
Nobuhito Morota, Satoshi Ihara, Hideki Ogiwara, Goichiro Tamura
OBJECTIVE Chondrodysplasia punctata (CDP), a rare skeletal dysplasia, can lead to cervical spine instability and deformity. However, an optimal neurosurgical intervention has yet to be established. Thus, a retrospective study was conducted to assess the efficacy of various surgical interventions for children with CDP. METHODS The authors retrospectively reviewed 9 cases of CDP in which cervical decompression with or without posterior fusion was performed between April 2007 and May 2016. Patient demographics, preoperative clinical conditions, radiographic findings, surgical procedures, and the postoperative course were analyzed in detail...
August 11, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28797833/percutaneous-rupture-of-zygapophyseal-joint-synovial-cysts-a-prospective-assessment-of-nonsurgical-management
#12
Gregory E Lutz, Michael R Nicoletti, George E Cyril, Julian R Harrison, Christopher Lutz, Jennifer L Solomon, Paul M Cooke, James F Wyss, Richard J Herzog, Peter J Moley
BACKGROUND: Although lumbar zygapophyseal joint synovial cysts are fairly well recognized, they are an uncommon cause of lumbosacral radicular pain. Non-operative treatments include percutaneous aspiration of the cysts under computed tomography or fluoroscopic guidance with a subsequent corticosteroid injection. However, there are mixed results in terms of long-term outcomes and cyst reoccurrence. This study prospectively evaluates percutaneous ruptures of zygapophyseal joint (Z-joint) synovial cysts for the treatment of lumbosacral radicular pain...
August 7, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28796260/clinical-grade-human-umbilical-cord-derived-mesenchymal-stem-cells-reverse-cognitive-aging-via-improving-synaptic-plasticity-and-endogenous-neurogenesis
#13
Ning Cao, Tuling Liao, Jiajing Liu, Zeng Fan, Quan Zeng, Junnian Zhou, Haiyun Pei, Jiafei Xi, Lijuan He, Lin Chen, Xue Nan, Yali Jia, Wen Yue, Xuetao Pei
Cognitive aging is a leading public health concern with the increasing aging population, but there is still lack of specific interventions directed against it. Recent studies have shown that cognitive function is intimately affected by systemic milieu in aging brain, and improvement of systemic environment in aging brain may be a promising approach for rejuvenating cognitive aging. Here, we sought to study the intervention effects of clinical-grade human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) on cognitive aging in a murine model of aging...
August 10, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28774451/interventions-and-therapy-in-rheumatology
#14
REVIEW
Mario Muto, Francesco Giurazza, Giulia Frauenfelder, Stefano Marcia, Salvatore Masala, Gianluigi Guarnieri
Patients affected by rheumatic conditions frequently present with spine degeneration and vertebral compression fractures, mainly related to the long-term therapies with glucocorticosteroids. A mini-invasive approach provided by interventional radiology techniques, especially vertebroplasty, plays a relevant role in the pain management of these patients; vertebroplasty represents the symptomatic treatment of fracture pain, so patients must always be included in a specific therapeutic workup of the rheumatic condition...
September 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/28771864/back-school-programme-for-nurses-has-reduced-low-back-pain-levels-a-randomized-controlled-trial
#15
M Járomi, A Kukla, B Szilágyi, Á Ugron, V Kovácsné Bobály, A Makai, P Linek, P Ács, E Leidecker
BACKGROUND: Millions of nurses around the world suffer from occupational-related chronic non-specific low back pain (cnsLBP). Generally, LBP in nurses is a result of increased pressure on the spine, and can be associated with improperly conducted patient lifting techniques. AIMS AND OBJECTIVES: The purposes of the study were:1) to examine patient lifting techniques used by nurses; and 2) to evaluate an effectiveness of the Spine Care for Nurses programme in cnsLBP reduction and the execution of proper patient lifting techniques...
August 3, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28767002/employment-status-five-years-after-a-randomised-controlled-trial-comparing-multidisciplinary-and-brief-intervention-in-employees-on-sick-leave-due-to-low-back-pain
#16
Pernille Pedersen, Claus Vinther Nielsen, Ole Kudsk Jensen, Chris Jensen, Merete Labriola
AIMS: To evaluate differences in employment status, during a five-year follow-up period in patients on sick leave due to low back pain who had participated in a trial comparing a brief and a multidisciplinary intervention. METHODS: From 2004 to 2008, 535 patients were referred to the Spine Centre at the Regional Hospital in Silkeborg if they had been on sick leave for 3-16 weeks due to low back pain. All patients underwent a clinical examination by a rehabilitation physician and a physiotherapist, and were randomised to either the brief intervention or the multidisciplinary intervention...
August 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28764281/immediate-effects-of-paraspinal-dry-needling-in-patients-with-acute-facet-joint-lock-induced-wry-neck
#17
Sukumar Shanmugam, Lawrence Mathias
INTRODUCTION: Acute facet joint lock induced wry neck (AFJL-WN) is common among adult population and it is primarily managed by medications and physiotherapy. However, the immediate recovery from pain and movements restriction caused by AFJL-WN is not documented in favour of existing interventions. AIM: To evaluate the immediate effects of paraspinal dry needling (PSDN) on acute neck pain and movement deficit in patients with AFJL-WN. MATERIALS AND METHODS: A total of 21 patients with AFJL-WN were treated with single session of PSDN for 12-15 minutes...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28763410/risk-factors-for-prolonged-opioid-use-following-spine-surgery-and-the-association-with-surgical-intensity-among-opioid-naive-patients
#18
Andrew J Schoenfeld, Kenneth Nwosu, Wei Jiang, Allan L Yau, Muhammad Ali Chaudhary, Rebecca E Scully, Tracey Koehlmoos, James D Kang, Adil H Haider
BACKGROUND: There is a growing concern that the use of prescription opioids following surgical interventions, including spine surgery, may predispose patients to chronic opioid use and abuse. We sought to estimate the proportion of patients using opioids up to 1 year after discharge following common spinal surgical procedures and to identify factors associated with sustained opioid use. METHODS: This study utilized 2006 to 2014 data from TRICARE insurance claims obtained from the Military Health System Data Repository...
August 2, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28761518/factors-affecting-outcome-of-acute-cervical-spine-injury-a-prospective-study
#19
Bhavanam Hanuma Srinivas, Alugolu Rajesh, A K Purohit
BACKGROUND: Injury to the spine and spinal cord is one of the common cause of disability and death. Several factors affect the outcome; but which are these factors (alone and in combination), are determining the outcomes are still unknown. The aim of the study was to evaluate the factors influencing the outcome following acute cervical spine injury. MATERIALS AND METHODS: A prospective observational study at single-center with all patients with cervical spinal cord injury (SCI), attending our hospital within a week of injury during a period of October 2011 to July 2013 was included for analysis...
July 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28760030/cervical-vertebroplasty-for-osteolytic-metastases-as-a-minimally-invasive-therapeutic-option-in-oncological-surgery-outcome-in-14-cases
#20
Martin Stangenberg, Lennart Viezens, Sven O Eicker, Malte Mohme, Klaus C Mende, Marc Dreimann
OBJECTIVE The treatment of cervical spinal metastases represents a controversial issue regarding the type, extent, and invasiveness of interventions. In the lumbar and thoracic spine, kypho- and vertebroplasties have been established as minimally invasive procedures for patients with metastases to the vertebral bodies and without neurological deficit. These procedures show good results with respect to pain reduction and low complication rates. However, limited data are available for kypho- and vertebroplasties for cervical spinal metastases...
August 2017: Neurosurgical Focus
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