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https://www.readbyqxmd.com/read/29168475/chronic-kidney-disease
#1
REVIEW
Paola Romagnani, Giuseppe Remuzzi, Richard Glassock, Adeera Levin, Kitty J Jager, Marcello Tonelli, Ziad Massy, Christoph Wanner, Hans-Joachim Anders
Chronic kidney disease (CKD) is defined by persistent urine abnormalities, structural abnormalities or impaired excretory renal function suggestive of a loss of functional nephrons. The majority of patients with CKD are at risk of accelerated cardiovascular disease and death. For those who progress to end-stage renal disease, the limited accessibility to renal replacement therapy is a problem in many parts of the world. Risk factors for the development and progression of CKD include low nephron number at birth, nephron loss due to increasing age and acute or chronic kidney injuries caused by toxic exposures or diseases (for example, obesity and type 2 diabetes mellitus)...
November 23, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29168458/antipsychotic-treatment-psychoeducation-regular-follow-up-as-a-public-health-strategy-for-schizophrenia-results-from-a-prospective-study
#2
Channaveerachari Naveen Kumar, Jagadisha Thirthalli, Kudumallige K Suresha, Basappa K Venkatesh, Udupi Arunachala, Bangalore N Gangadhar
BACKGROUND & OBJECTIVES: In low- and middle-income countries such as India, a feasible public health strategy could be to ensure continuous antipsychotics and psychoeducation for those with schizophrenia. Whether such a strategy favourably influences its course and outcome is not well-studied. The objectives of this study were to examine these issues in a cohort of patients with schizophrenia in a rural south Indian taluk (an administrative block). This cohort was part of a community intervention programme running in the place since the past one decade...
July 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29168069/sexual-stigma-patterns-among-nigerian-men-who-have-sex-with-men-and-their-link-to-hiv-and-sexually-transmitted-infection-prevalence
#3
Cristina Rodriguez-Hart, Rashelle Musci, Rebecca G Nowak, Danielle German, Ifeanyi Orazulike, Uchenna Ononaku, Hongjie Liu, Trevor A Crowell, Stefan Baral, Man Charurat
Sexual stigma facilitates the spread of HIV and sexually transmitted infections (STIs) but little is known about stigma affecting Nigerian men who have sex with men (MSM). We assessed patterns of sexual stigma across Nigerian MSM and their relationship to HIV and STIs. Data were collected from the TRUST/RV368 Study, a prospective cohort of 1480 Nigerian MSM enrolled from March 2013 to February 2016 using respondent driven sampling. Structural equation modeling was utilized to assess the association between stigma classes and HIV and STI prevalence, adjusting for participants' characteristics...
November 22, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/29168005/a-survey-by-the-european-society-of-breast-imaging-on-the-utilisation-of-breast-mri-in-clinical-practice
#4
Paola Clauser, Ritse Mann, Alexandra Athanasiou, Helmut Prosch, Katja Pinker, Matthias Dietzel, Thomas H Helbich, Michael Fuchsjäger, Julia Camps-Herrero, Francesco Sardanelli, Gabor Forrai, Pascal A T Baltzer
OBJECTIVES: While magnetic resonance imaging (MRI) is considered a helpful diagnostic tool in breast imaging, discussions are ongoing about appropriate protocols and indications. The European Society of Breast Imaging (EUSOBI) launched a survey to evaluate the utilisation of breast MRI in clinical practice. METHODS: An online survey reviewed by the EUSOBI board and committees was distributed amongst members. The questions encompassed: training and experience; annual breast MRI and MRI-guided-intervention workload; examination protocols; indications; reporting habits and preferences...
November 22, 2017: European Radiology
https://www.readbyqxmd.com/read/29167793/health-and-lifestyles-factors-associated-with-osteoarthritis-among-older-adults-in-portugal
#5
Natália Duarte, Ana Maria Rodrigues, Jaime Da Cunha Branco, Helena Canhão, Susan L Hughes, Constança Paúl
Objective: This study aimed to identify independent associations of sociodemographic, functionality, physical activity, physical and mental health, and osteoarthritis (OA), among older adults. Methods: A sample of 1,645 older adults (50+ years) observed by rheumatologists, from EpiReumaPt, a population-based study was analyzed. A structured interview included sociodemographic data, chronic non-communicable disease, and physical activity. Functional ability was assessed by the Health Assessment Questionnaire Disability Index; depression and anxiety were assessed by Hospital Anxiety and Depression Scale...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29167340/hadv-protein-v-core-protein-is-targeted-by-the-host-sumoylation-machinery-to-limit-essential-viral-functions
#6
Nora Freudenberger, Tina Meyer, Peter Groitl, Thomas Dobner, Sabrina Schreiner
Human Adenoviruses (HAdV) are non-enveloped containing a linear, double-stranded DNA genome surrounded by an icosahedral capsid. To allow proper viral replication, the genome is imported through the nuclear-pore-complex associated with viral core proteins. Until now, the role of these incoming virion proteins during the early phase of infection was poorly understood.The core protein V is speculated to bridge core and the surrounding capsid. It binds the genome in a sequence-independent manner and localizes in the nucleus of infected cells, accumulating at nucleoli...
November 22, 2017: Journal of Virology
https://www.readbyqxmd.com/read/29167035/promoting-empathy-among-medical-students-a-two-site-randomized-controlled-study
#7
Céline Buffel du Vaure, Cédric Lemogne, Lucie Bunge, Annie Catu-Pinault, Nicolas Hoertel, Christian Ghasarossian, Marie-Eve Vincens, Eric Galam, Philippe Jaury
OBJECTIVE: To assess the effects of Balint groups on empathy measured by the Consultation And Relational Empathy Measure (CARE) scale rated by standardized patients during objective structured clinical examination and self-rated Jefferson's School Empathy Scale - Medical Student (JSPE-MS©) among fourth-year medical students. METHODS: A two-site randomized controlled trial were planned, from October 2015 to December 2015 at Paris Diderot and Paris Descartes University, France...
December 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29166905/barriers-to-data-quality-resulting-from-the-process-of-coding-health-information-to-administrative-data-a-qualitative-study
#8
Kelsey Lucyk, Karen Tang, Hude Quan
BACKGROUND: Administrative health data are increasingly used for research and surveillance to inform decision-making because of its large sample sizes, geographic coverage, comprehensivity, and possibility for longitudinal follow-up. Within Canadian provinces, individuals are assigned unique personal health numbers that allow for linkage of administrative health records in that jurisdiction. It is therefore necessary to ensure that these data are of high quality, and that chart information is accurately coded to meet this end...
November 22, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29166770/maltreatment-coping-and-substance-use-in-youth-in-foster-care-examination-of-moderation-models
#9
Joy Gabrielli, Yo Jackson, Lindsay Huffhines, Katie Stone
Child maltreatment is associated with negative outcomes such as substance use (SU). This study tested relations among maltreatment history, coping behavior, and SU behavior in youth residing in foster care. Participants were 210 youth ( Mage = 12.71 years; SD = 2.95) in foster care who completed self-report measures through an audio computer-assisted self-interview program. Using a structural equation modeling framework and latent measurement constructs, positive associations were identified between maltreatment at baseline and coping behavior outcomes as well as SU behavior outcome approximately 4...
January 1, 2017: Child Maltreatment
https://www.readbyqxmd.com/read/29166560/analytical-challenges-and-recent-advances-in-mass-spectrometry-based-lipidomics
#10
Yepy Hardi Rustam, Gavin Edmund Reid
Although no internationally accepted consensus definition exists, lipids can be broadly defined as "fatty acids and their derivatives, and substances related biosynthetically or functionally to these compounds". Lipids play critical roles as (i) the major structural components of biological membranes, and as functional and regulatory components of membrane protein signaling, (ii) bioactive intra- and inter-cellular signaling molecules, and (iii) energy storage molecules for the maintenance of energy homeostasis...
November 22, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29166243/building-capacity-for-evidence-based-public-health-reconciling-the-pulls-of-practice-and-the-push-of-research
#11
Ross C Brownson, Jonathan E Fielding, Lawrence W Green
Timely implementation of principles of evidence-based public health (EBPH) is critical for bridging the gap between discovery of new knowledge and its application. Public health organizations need sufficient capacity (the availability of resources, structures, and workforce to plan, deliver, and evaluate the preventive dose of an evidence-based intervention) to move science to practice. We review principles of EBPH, the importance of capacity building to advance evidence-based approaches, promising approaches for capacity building, and future areas for research and practice...
November 20, 2017: Annual Review of Public Health
https://www.readbyqxmd.com/read/29165967/measurements-of-self-efficacy-in-patients-with-chronic-kidney-disease-a-literature-review
#12
Yu-Jie Guo, Qing Tang, Yu Gu
This article reviews the literature addressing assessment instruments about various aspects of self-efficacy in patients with chronic kidney disease (CKD). Each scale's structure, reliability, validity, and clinical application are described in detail. When selecting assessment tools to measure the self-efficacy level of patients with CKD, we should take the suitable subjects and application scope into account. With valid and reliable measurement tools, researchers and clinical nurses can assess and stimulate the self-efficacy of patients with CKD more effectively and carry out targeted nursing interventions so as to improve patients' self-efficacy level...
March 2017: Nephrology Nursing Journal: Journal of the American Nephrology Nurses' Association
https://www.readbyqxmd.com/read/29165825/understanding-the-lived-experiences-of-parkinson-s-disease-and-deep-brain-stimulation-dbs-through-occupational-changes
#13
Jacki Liddle, Jessie Phillips, Louise Gustafsson, Peter Silburn
BACKGROUND: Deep brain stimulation (DBS), a surgically based treatment for people living with Parkinson's disease (PD), can result in a significant improvement of motor symptoms. However, the broader impact of DBS and the changes it creates are not well understood. Greater understanding of the experiences and needs related to DBS would enable development of relevant outcome measures and supports. OBJECTIVES: To explore the lived experiences of people undergoing DBS for Parkinson's disease...
November 22, 2017: Australian Occupational Therapy Journal
https://www.readbyqxmd.com/read/29164435/written-expression-in-individuals-with-autism-spectrum-disorder-a-meta-analysis
#14
Elizabeth Finnegan, Amy L Accardo
Although studies exist measuring the effectiveness of writing interventions for students with autism spectrum disorder (ASD), research assessing the writing skills for this group is sparse. The present study identified differences in the written expression of individuals with ASD compared to typically developing (TD) peers, using variables selected from 13 different studies. Using Pearson Product Moment-correlation the relationship between the quality of research studies and the magnitude of the effect sizes was examined...
November 21, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29164180/you-can-t-burn-the-house-down-because-of-one-bedbug-a-qualitative-study-of-changing-gender-norms-in-the-prevention-of-violence-against-women-and-girls-in-an-urban-informal-settlement-in-india
#15
Nayreen Daruwalla, Ketaki Hate, Preethi Pinto, Gauri Ambavkar, Bhaskar Kakad, David Osrin
Background: The contribution of structural inequalities and societal legitimisation to violence against women, which 30% of women in India survive each year, is widely accepted. There is a consensus that interventions should aim to change gender norms, particularly through community mobilisation. How this should be done is less clear. Methods: We did a qualitative study in a large informal settlement in Mumbai, an environment that characterises 41% of households. After reviewing the anonymised records of consultations with 1653 survivors of violence, we conducted 5 focus group discussions and 13 individual interviews with 71 women and men representing a range of age groups and communities...
2017: Wellcome Open Research
https://www.readbyqxmd.com/read/29164165/platelet-rich-plasma-for-primary-treatment-of-partial-ulnar-collateral-ligament-tears-mri-correlation-with-results
#16
J Banks Deal, Ed Smith, Wendell Heard, Michael J O'Brien, Felix H Savoie
Background: Jobe revolutionized the treatment of medial ulnar collateral ligament (MUCL) tears with his reconstruction technique. However, not all MUCL injuries require operative management; Rettig showed that 42% of MUCL injuries respond to conservative management. This was improved by Podesta, who showed that augmentation of nonoperative management with platelet-rich plasma (PRP) and magnetic resonance imaging (MRI) for detecting partial MUCL tears resulted in significantly higher success rates...
November 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29164129/a-commercially-available-portion-controlled-diet-program-is-more-effective-for-weight-loss-than-a-self-directed-diet-results-from-a-randomized-clinical-trial
#17
Chad M Cook, Courtney N McCormick, Mandi Knowles, Valerie N Kaden
Objective: To examine changes in weight and related outcomes in response to a commercial weight loss program compared to a self-directed diet in adults with overweight or obesity. Design: Participants were randomly assigned [stratified by body mass index (BMI) and age] to a commercial weight loss program (n = 38) or to a self-directed Dietary Approaches to Stop Hypertension (DASH) diet (n = 40) for a 16-week period. Daily energy intake goals were 1,500 kcal/d for men and 1,200 kcal/d for women, except for the first week of the commercial program (1,000 kcal/d)...
2017: Frontiers in Nutrition
https://www.readbyqxmd.com/read/29164035/a-clinical-practice-guideline-for-the-management-of-patients-with-degenerative-cervical-myelopathy-recommendations-for-patients-with-mild-moderate-and-severe-disease-and-nonmyelopathic-patients-with-evidence-of-cord-compression
#18
Michael G Fehlings, Lindsay A Tetreault, K Daniel Riew, James W Middleton, Bizhan Aarabi, Paul M Arnold, Darrel S Brodke, Anthony S Burns, Simon Carette, Robert Chen, Kazuhiro Chiba, Joseph R Dettori, Julio C Furlan, James S Harrop, Langston T Holly, Sukhvinder Kalsi-Ryan, Mark Kotter, Brian K Kwon, Allan R Martin, James Milligan, Hiroaki Nakashima, Narihito Nagoshi, John Rhee, Anoushka Singh, Andrea C Skelly, Sumeet Sodhi, Jefferson R Wilson, Albert Yee, Jeffrey C Wang
Study Design: Guideline development. Objectives: The objective of this study is to develop guidelines that outline how to best manage (1) patients with mild, moderate, and severe myelopathy and (2) nonmyelopathic patients with evidence of cord compression with or without clinical symptoms of radiculopathy. Methods: Five systematic reviews of the literature were conducted to synthesize evidence on disease natural history; risk factors of disease progression; the efficacy, effectiveness, and safety of nonoperative and surgical management; the impact of preoperative duration of symptoms and myelopathy severity on treatment outcomes; and the frequency, timing, and predictors of symptom development...
September 2017: Global Spine Journal
https://www.readbyqxmd.com/read/29163990/interventional-pain-management-in-multidisciplinary-chronic-pain-clinics-a-prospective-multicenter-cohort-study-with-one-year-follow-up
#19
Cláudia Gouvinhas, Dalila Veiga, Liliane Mendonça, Rute Sampaio, Luís Filipe Azevedo, José Manuel Castro-Lopes
Background: Interventional Pain Management (IPM) is performed in multidisciplinary chronic pain clinics (MCPC), including a range of invasive techniques to diagnose and treat chronic pain (CP) conditions. Current patterns of use of those techniques in MCPC have not yet been reported. Objective: We aimed to describe quantitatively and qualitatively the use of IPM and other therapeutic procedures performed on-site at four Portuguese MCPC. Methods: A prospective cohort study with one-year follow-up was performed in adult patients...
2017: Pain Research and Treatment
https://www.readbyqxmd.com/read/29163981/a-comparison-of-isometric-isotonic-concentric-and-isotonic-eccentric-exercises-in-the-physiotherapy-management-of-subacromial-pain-syndrome-rotator-cuff-tendinopathy-study-protocol-for-a-pilot-randomised-controlled-trial
#20
Rita Kinsella, Sallie M Cowan, Lyn Watson, Tania Pizzari
Background: Subacromial pain syndrome (SPS) involving rotator cuff tendinopathy is a common cause of shoulder pain and disability. Evidence suggests that structured physiotherapy may be as effective as surgery in this condition with significant improvements demonstrated in trials involving scapular retraining, rotator cuff strengthening and flexibility exercises. Most published programs typically utilise isotonic concentric and/or eccentric strengthening modes. Recently, immediate analgesic effects and muscle strength gains following heavy-load isometric exercises in lower limb tendinopathy conditions have been observed...
2017: Pilot and Feasibility Studies
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