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https://www.readbyqxmd.com/read/29150862/randomised-crossover-trial-showed-that-using-breast-milk-or-sucrose-provided-the-same-analgesic-effect-in-preterm-infants-of-at-least-28-weeks
#1
L Collados-Gómez, P Ferrera-Camacho, E Fernandez-Serrano, V Camacho-Vicente, C Flores-Herrero, A M García-Pozo, R Jiménez-García
AIM: Repeated, on-going exposure to pain influences the growth, cognitive and motor functions, behaviour, personality and neurodevelopment of preterm infants. We compared the analgesic effects of expressed breast milk and 24% oral sucrose on preterm neonates during venipuncture. METHODS: This multicentre randomised, non-inferiority, cross-over trial focused on five neonatal university units in Madrid, Spain, from October 2013 to October 2014. It comprised 66 preterm infants born at less than 37 weeks and randomly split into two groups...
November 18, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29150457/combination-analgesia-for-neonatal-circumcision-a-randomized-controlled-trial
#2
Rana Sharara-Chami, Zavi Lakissian, Lama Charafeddine, Nadine Milad, Yaser El-Hout
OBJECTIVES: There is no consensus on the most effective pain management for neonatal circumcision. We sought to compare different modalities. METHODS: This is a double-blinded randomized controlled trial comparing 3 combination analgesics used during circumcision (EMLA + sucrose; EMLA + sucrose + dorsal penile nerve block [DPNB]; EMLA + sucrose + ring block [RB]) with the traditional topical analgesic cream EMLA alone. The trial was set in the normal nursery of a teaching hospital...
November 17, 2017: Pediatrics
https://www.readbyqxmd.com/read/29144393/growth-gastrointestinal-tolerance-and-stool-characteristics-of-healthy-term-infants-fed-an-infant-formula-containing-hydrolyzed-whey-protein-63-and-intact-casein-37-a-randomized-clinical-trial
#3
Shang-Ling Wu, Ding Ding, Ai-Ping Fang, Pei-Yan Chen, Si Chen, Li-Peng Jing, Yu-Ming Chen, Hui-Lian Zhu
To investigate whether healthy term infants, fed an infant formula containing hydrolyzed whey protein (HWP-F, hydrolyzed whey/intact casein =63/37), differ in growth, gastrointestinal tolerance and stool characteristics from those fed an infant formula containing intact whey protein (IWP-F, intact whey/intact casein =61/39) or breast milk. Healthy term infants, born within 14 days of the study's commencement, were randomly assigned to be fed IWP-F or HWP-F until 13 weeks of age, and breast-fed (BF) infants were enrolled as a reference group...
November 16, 2017: Nutrients
https://www.readbyqxmd.com/read/29118383/impact-of-lactobacillus-reuteri-colonization-on-gut-microbiota-inflammation-and-crying-time-in-infant-colic
#4
Monica L Nation, Eileen M Dunne, Shayne J Joseph, Fiona K Mensah, Valerie Sung, Catherine Satzke, Mimi L K Tang
Infant colic is a distressing condition of unknown etiology. An aberrant gastrointestinal microbiota has been associated, and Lactobacillus reuteri supplementation has been shown to reduce crying and/or fussing time ('crying time') in some infants with colic. The relationship between L. reuteri gut colonization and crying time has not been examined. We investigated the relationship between L. reuteri colonization and fecal microbiota (microbial diversity and Escherichia coli), intestinal inflammation, and crying time in infants with colic, using a subset of 65 infants from the Baby Biotics trial, which randomized healthy term infants aged <13 weeks with infant colic to receive probiotic L...
November 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29113376/efficacy-of-glucocorticoids-vitamin-a-and-caffeine-therapies-for-neonatal-mortality-in-preterm-infants-a-network-meta-analysis
#5
Ying Li, Jie Gao, Qiwei Wang, Xiaojian Ma
Introduction: The paper aimed to evaluate the efficacy of different therapies in improving survival among preterm infants. Materials and Methods: PubMed and Embase were searched from inception to 2017. We assessed studies for eligibility and extracted data. A Bayesian random-effects model was used to evaluate different therapies combined direct comparisons with indirect evidence. Consistency analysis was achieved using node-splitting plots. Surface under the cumulative ranking curve (SUCRA) was calculated to rank different therapies...
October 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/29108736/a-randomized-double-blind-trial-comparing-the-effect-on-pain-of-an-oral-sucrose-solution-vs-placebo-in-children-1-to-3%C3%A2-months-old-undergoing-simple-venipuncture
#6
Serge Gouin, Nathalie Gaucher, Denis Lebel, Marie Pier Desjardins
BACKGROUND: Few clinical trials evaluating the efficacy of oral sweet solutions for procedures in the emergency department (ED) have been published. OBJECTIVES: To compare the efficacy of an oral sucrose solution vs. a placebo in reducing pain in infants undergoing venipuncture without cannulation. METHODS: A randomized, double-blinded clinical trial was conducted in a pediatric ED. Infants 1 to 3 months old were randomly allocated to receive 2 mL of 88% sucrose or 2 mL of placebo, 2 min prior to venipuncture...
November 3, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29078366/neurobiology-of-culturally-common-maternal-responses-to-infant-cry
#7
Marc H Bornstein, Diane L Putnick, Paola Rigo, Gianluca Esposito, James E Swain, Joan T D Suwalsky, Xueyun Su, Xiaoxia Du, Kaihua Zhang, Linda R Cote, Nicola De Pisapia, Paola Venuti
This report coordinates assessments of five types of behavioral responses in new mothers to their own infants' cries with neurobiological responses in new mothers to their own infants' cries and in experienced mothers and inexperienced nonmothers to infant cries and other emotional and control sounds. We found that 684 new primipara mothers in 11 countries (Argentina, Belgium, Brazil, Cameroon, France, Kenya, Israel, Italy, Japan, South Korea, and the United States) preferentially responded to their infants' vocalizing distress by picking up and holding and by talking to their infants, as opposed to displaying affection, distracting, or nurturing...
November 7, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29026733/safety-of-a-new-synbiotic-starter-formula
#8
Yvan Vandenplas, Antonis Analitis, Chara Tziouvara, Athina Kountzoglou, Anastasia Drakou, Manos Tsouvalas, Antigoni Mavroudi, Ioannis Xinias
PURPOSE: Breastfeeding is the best way to feed all infants, but not all infants can be (exclusively) breastfed. Cow's milk based infant formula is the second choice infant feeding. METHODS: The safety of a new synbiotic infant formula, supplemented with Bifidobacterium lactis and fructo-oligosaccharides, with lactose and a whey/casein 60/40 protein ratio was tested in 280 infants during 3 months. RESULTS: The median age of the infants at inclusion was 0...
September 2017: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/29018790/synergistic-effects-of-unintended-pregnancy-and-young-motherhood-on-shaking-and-smothering-of-infants-among-caregivers-in-nagoya-city-japan
#9
Aya Isumi, Takeo Fujiwara
BACKGROUND: Shaking and smothering in response to infant crying are forms of child abuse that often result in death. Unintended pregnancy and young motherhood are risk factors of such child maltreatment that are often comorbid, few studies have examined their synergistic effect on shaking and smothering of infants. We examined the synergistic effects of unintended pregnancy and young motherhood on shaking and smothering among caregivers of infants in Japan. METHODS: In this retrospective cohort study, a questionnaire was administered to caregivers enrolled for a health check for 3- to 4-month-old infants between October 2013 and February 2014 in Nagoya City, Japan...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28987983/maternal-self-confidence-during-the-first-four-months-postpartum-and-its-association-with-anxiety-and-early-infant-regulatory-problems
#10
Lina Maria Matthies, Stephanie Wallwiener, Mitho Müller, Anne Doster, Katharina Plewniok, Sandra Feller, Christof Sohn, Markus Wallwiener, Corinna Reck
Maternal self-confidence has become an essential concept in understanding early disturbances in the mother-child relationship. Recent research suggests that maternal self-confidence may be associated with maternal mental health and infant development. The current study investigated the dynamics of maternal self-confidence during the first four months postpartum and the predictive ability of maternal symptoms of depression, anxiety, and early regulatory problems in infants. Questionnaires assessing symptoms of depression (Edinburgh Postnatal Depression Scale), anxiety (State-Trait Anxiety Inventory), and early regulatory problems (Questionnaire for crying, sleeping and feeding) were completed in a sample of 130 women at three different time points (third trimester (T1), first week postpartum (T2), and 4 months postpartum (T3)...
October 5, 2017: Infant Behavior & Development
https://www.readbyqxmd.com/read/28969890/lactobacillus-reuteri-for-infants-with-colic-a-double-blind-placebo-controlled-randomized-clinical-trial
#11
Nicole Y Fatheree, Yuying Liu, Christopher M Taylor, Thomas K Hoang, Chunyan Cai, Mohammad H Rahbar, Manouchehr Hessabi, Michael Ferris, Valarie McMurtry, Christine Wong, Ta Vu, Theresa Dancsak, Ting Wang, Wallace Gleason, Vinay Bandla, Fernando Navarro, Dat Q Tran, J Marc Rhoads
OBJECTIVE: To assess the safety of probiotic Lactobacillus reuteri strain Deutsche Sammlung von Mikroorganismen (DSM) 17938 with daily administration to healthy infants with colic and to determine the effect of L reuteri strain DSM 17938 on crying, fussing, inflammatory, immune, and microbiome variables. STUDY DESIGN: We performed a controlled, double-blinded, phase 1 safety and tolerability trial in healthy breast-fed infants with colic, aged 3 weeks to 3 months, randomly assigned to L reuteri strain DSM 17938 (5 × 10(8) colony-forming units daily) or placebo for 42 days and followed for 134 days...
September 29, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28969887/crying-time-and-ror%C3%AE-foxp3-expression-in-lactobacillus-reuteri-dsm17938-treated-infants-with-colic-a-randomized-trial
#12
Francesco Savino, Maria Garro, Paola Montanari, Ilaria Galliano, Massimiliano Bergallo
OBJECTIVES: To evaluate crying time, retinoid-related orphan receptor-γ (RORγ) and forkhead box P3 (FOXP3) messenger RNA levels (transcription factors that can modulate T cell responses to gut microbes), and to investigate gut microbiota and fecal calprotectin in infants treated with Lactobacillus reuteri for infantile colic. STUDY DESIGN: A double-blind, placebo-controlled randomized trial was conducted in primary care in Torino from August 1, 2015 to September 30, 2016...
September 29, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28959231/demographic-clinical-and-immunologic-features-of-389-children-with-opsoclonus-myoclonus-syndrome-a-cross-sectional-study
#13
Michael R Pranzatelli, Elizabeth D Tate, Nathan R McGee
Pediatric-onset opsoclonus-myoclonus syndrome (OMS) is a devastating neuroinflammatory, often paraneoplastic, disorder. The objective was to characterize demographic, clinical, and immunologic aspects in the largest cohort reported to date. Cross-sectional data were collected on 389 children in an IRB-approved, observational study at the National Pediatric Myoclonus Center. Non-parametric statistical analysis was used. OMS manifested in major racial/ethnic groups, paralleling US population densities. Median onset age was 1...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28957433/fathering-style-influences-health-outcome-in-common-marmoset-callithrix-jacchus-offspring
#14
Toni E Ziegler, Megan E Sosa, Ricki J Colman
In the cooperative breeding common marmoset monkey, Callithrix jacchus, fathers share the care responsibility and energetic load with their mate from the time their infants are born. However, not all fathers show the same level of participation in direct infant care. Here we present the first results demonstrating that fathering style can improve both survival and growth trajectory of a male's offspring during the first 30 weeks of life and that these infant outcomes are consistent within a father throughout successive births...
2017: PloS One
https://www.readbyqxmd.com/read/28952975/infant-resuscitation-practices-of-midwives-in-a-developing-country
#15
Wadah Khriesat, Manal Kassab, Shereen Hamadneh, Khitam Mohammad, Jehan Hamadneh, Yousef S Khader
BACKGROUND: Effective basic newborn resuscitation is an important strategy to reduce the incidence of birth asphyxia and associated newborn outcomes. Outcomes for newborns can be markedly improved if health providers have appropriate newborn resuscitation skills. PURPOSE: To evaluate the skills of midwives in newborn resuscitation in delivery rooms in Jordan. METHODS: Data were collected from observation of 118 midwives from National Health Service hospitals in the north of Jordan who performed basic newborn resuscitation for full-term neonates...
August 4, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/28946688/role-of-high-resolution-chest-computed-tomography-in-a-child-with-persistent-tachypnoea-and-intercostal-retractions-a-case-report-of-neuroendocrine-cell-hyperplasia
#16
Mara Lelii, Maria Francesca Patria, Raffaella Pinzani, Rossana Tenconi, Alessandro Mori, Nicola Bonelli, Nicola Principi, Susanna Esposito
Background: Chronic interstitial lung diseases in children (chILD) are a heterogeneous group of disorders that can represent a clinical challenge for pediatric pneumologists. Among them, neuroendocrine cell hyperplasia of infancy (NEHI) is a diffuse lung disease prevalent in the first years of life that spontaneously improves over time. The clinical presentation of NEHI is indistinguishable from other interstitial lung diseases, so a correct and non-invasive diagnosis by chest computed tomography (CT) without lung biopsy might not be simple...
September 25, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28917387/affective-reactivity-to-cry-sounds-predicts-young-women-s-reactivity-and-behavior-in-a-simulated-caregiving-task
#17
Gwen E Gustafson, Jennifer B Bisson, Jillian M MacDonald, James A Green
Different populations of adults (experienced vs. inexperienced caregivers, men vs. women, abusive vs. nonabusive parents, etc.) have been reported to differ in their affective reactions to the sounds of infant crying. These differences are thought to impact caregiving behavior and, in some instances, to affect long-term outcomes for infants. There can be great intra-group variation, however, even when group differences are significant; modeling developmental process will require a finer grained approach. We have undertaken a pair of studies intended to validate the Negative Affect Scale (NA) from the PANAS as a measure of individuals' affective reactivity to cry sounds...
September 13, 2017: Infant Behavior & Development
https://www.readbyqxmd.com/read/28900745/systematic-review-on-maternal-depression-versus-anxiety-in-relation-to-excessive-infant-crying-it-is-all-about-the-timing
#18
REVIEW
Johanna Petzoldt
Different types of studies suggest a link between maternal depression/anxiety and excessive infant crying (EC). However, comparability is hampered due to different designs, definitions and measurements. This systematic review investigates the specific role of maternal depression and anxiety considering them as preceding, concurrent and subsequent conditions of EC. A computerised literature search was conducted in January 2017 using Medline, PubMed, PsycINFO and Web of Science. After screening n = 399 records for inclusion/exclusion criteria, n = 33 records based on n = 30 projects were eligible for systematic qualitative data synthesis...
September 13, 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/28894218/lactate-utilizing-community-is-associated-with-gut-microbiota-dysbiosis-in-colicky-infants
#19
Van T Pham, Christophe Lacroix, Christian P Braegger, Christophe Chassard
The aetiology of colic, a functional gastrointestinal disorder in infants, is not yet resolved. Different mechanisms have been suggested involving the gut microbiota and intermediate metabolites such as lactate. Lactate can be metabolized by lactate-utilizing bacteria (LUB) to form different end-products. Using a functional approach, we hypothesized that H2 production and accumulation by LUB is associated with the development of colic. The LUB communities in the feces of forty infants, including eight colicky infants, were characterized using a combination of culture- and molecular-based methods, and metabolite concentrations were measured by HPLC...
September 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28879564/the-effect-of-breathing-on-ductus-arteriosus-blood-flow-directly-after-birth
#20
Jeroen J van Vonderen, Arno A W Roest, Frans J C Klumper, Stuart B Hooper, Arjan B Te Pas
Spontaneous breathing at birth influences ductus arteriosus (DA) flow. This study quantifies the effect of breathing on DA shunting directly after birth. In healthy term infants born by elective cesarean section, simultaneous measurements of DA shunting and tidal volumes during spontaneous breathing were performed at 2-5, 5-8, and 10-13 min after birth. Eight infants with a mean (SD) gestational age of 40 (1) weeks and 3216 (616) grams were studied. Inspiratory tidal volume was 5.8 (3.3-7.7), 5.7 (4.0-7.1), and 5...
December 2017: European Journal of Pediatrics
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