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https://www.readbyqxmd.com/read/28528793/comparison-of-dual-energy-x-ray-absorptiometry-and-bioimpedance-in-assessing-body-composition-and-nutrition-in-peritoneal-dialysis-patients
#1
Velena Popovic, Bo Zerahn, James Goya Heaf
OBJECTIVE: Peritoneal dialysis (PD) patients are characterized by protein malnutrition and muscle wasting. Reliable, easy, and cheap methods for evaluating nutrition are desirable. Three methods are commonly available: dual-energy X-ray absorptiometry (DXA), bioimpedance (BI), and subjective global assessment (SGA).The objective of the study was to compare the previously mentioned methods for assessment of body composition and nutritional status in PD patients. DESIGN: The study is cross-sectional and consisted of 72 PD patients from a single center PD ambulatorium...
May 18, 2017: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/28514233/energy-balance-over-one-athletic-season
#2
Analiza M Silva, Catarina N Matias, Diana A Santos, Diana Thomas, Anja Bosy-Westphal, Manfred J Müller, Steven B Heymsfield, Luís B Sardinha
INTRODUCTION: Magnitude and variation in energy balance (EB) components over an athletic season are largely unknown. PURPOSE: We investigated the longitudinal changes in EB over one season and explored the association between EB variation and the change in the main fat-free mass (FFM) components in highly trained athletes. METHODS: Eighty athletes (54 males; handball, volleyball, basketball, triathlete, and swimming) were evaluated from the beginning of the season to the main competition stage...
March 22, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28454245/improving-contrast-enhancement-in-magnetic-resonance-imaging-using-5-aminolevulinic-acid-induced-protoporphyrin-ix-for-high-grade-gliomas
#3
Junkoh Yamamoto, Shingo Kakeda, Tetsuya Yoneda, Shun-Ichiro Ogura, Shohei Shimajiri, Tohru Tanaka, Yukunori Korogi, Shigeru Nishizawa
Magnetic resonance imaging (MRI) with a gadolinium-based contrast agent is the gold standard for high-grade gliomas (HGGs). The compound 5-aminolevulinic acid (5-ALA) undergoes a high rate of cellular uptake, particularly in cancer cells. In addition, fluorescence-guided resection with 5-ALA is widely used for imaging HGGs. 5-ALA is water soluble, while protoporphyrin IX (PpIX) is water insoluble. It was speculated whether converting from 5-ALA to PpIX may relatively increase intracellular water content, and consequently, might enhance the T2 signal intensity in HGG...
March 2017: Oncology Letters
https://www.readbyqxmd.com/read/28429114/physical-and-chemical-characteristics-of-the-longissimus-dorsi-from-swine-reared-in-climate-controlled-and-uncontrolled-environments
#4
Juliana Lolli Malagoli de Mello, Mariana Piatto Berton, Rita de Cassia Dourado, Aline Giampietro-Ganeco, Rodrigo Alves de Souza, Fábio Borba Ferrari, Pedro Alves de Souza, Hirasilva Borba
The aim of this study was to evaluate the effect of ambient temperature on the physical and chemical characteristics of the longissimus dorsi muscle by comparing the quality of meat from pigs reared in a controlled and in an uncontrolled environment, the latter provided with a shallow pool. Twenty castrated male pigs of the Topigs line were randomly allotted to two treatments: a controlled environment, with constant temperature (22 °C) and relative humidity (70%); and an uncontrolled environment in a conventional shed for rearing pigs equipped with a shallow pool, where pigs were subject to climatic variations...
April 20, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/28364696/differential-effects-of-liver-steatosis-on-pharmacokinetic-profile-of-two-closely-related-hepatoselective-no-donors-v-pyrro-no-and-v-proli-no
#5
Kamil Kus, Edyta Kus, Agnieszka Zakrzewska, Wojciech Jawien, Barbara Sitek, Maria Walczak, Stefan Chlopicki
PURPOSE: To analyze the effect of liver steatosis and obesity on pharmacokinetic profile of two structurally-related liver-selective NO-donors - V-PYRRO/NO and V-PROLI/NO. METHODS: C57BL/6 mice were fed control or high-fat diet for 15 weeks to induced liver steatosis and obesity (HFD mice). Pharmacokinetics and renal elimination studies were conducted in vivo following iv dosing of V-PYRRO/NO and V-PROLI/NO (0.03mmol/kg). Hepatic clearance was evaluated ex vivo in the isolated perfused mice liver and in vitro with the use of liver microsomes...
June 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28319679/evaluation-of-body-composition-with-bioimpedence-a-comparison-between-athletic-and-non-athletic-children
#6
Domenico Meleleo, Nicola Bartolomeo, Liliana Cassano, Alessandro Nitti, Giovanna Susca, Giuseppina Mastrototaro, Umberto Armenise, Annapaola Zito, Fiorella Devito, Pietro Scicchitano, Marco Matteo Ciccone
PURPOSE: Conventional Bioelectrical Impedance Analysis (BIA) or Bioelectrical Impedance Vector Analysis (BIVA) can provide direct evaluations of body composition. The purpose of this study was to evaluate lean and fat mass (FM), and hydration of children involved in daily competitive sports. METHODS: 190 non-athletic [8.2-10.5 years] and 29 competitive children [8.0-10.5 years] were enrolled. They were evaluated: at baseline (t0), 6 months (t1) and one year (t2)...
July 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28277301/body-composition-analysis-and-adipocytokine-concentrations-in-haemodialysis-patients-abdominal-fat-gain-as-an-additional-cardiovascular-risk-factor
#7
Elena González, Juan J Díez, Almudena Pérez Torres, María Auxiliadora Bajo, Gloria Del Peso, Rafael Sánchez-Villanueva, Cristina Grande, Olaia Rodríguez, Mónica Coronado, Carmen Gómez Candela, Mariana Díaz-Almirón, Pedro Iglesias, Rafael Selgas
INTRODUCTION: Abdominal fat and its increment over time in particular has become a cardiovascular risk factor in uraemic patients. OBJECTIVES: To analyse changes in abdominal fat in haemodialysis patients over one year and study their possible correlation with the variation in adipocytokine serum levels. As a secondary objective, we tried to validate the data obtained by bioelectrical impedance analysis (BIA) with data obtained by dual X-ray absorptiometry (DXA)...
March 2017: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/28255913/body-composition-anthropometric-indices-and-hydration-status-of-obstructive-sleep-apnea-patients-can-cachexia-coexist-with-obesity
#8
Barbara Kuźnar-Kamińska, Marcin Grabicki, Tomasz Trafas, Monika Szulińska, Szczepan Cofta, Tomasz Piorunek, Beata Brajer-Luftmann, Agata Nowicka, Barbara Bromińska, Halina Batura-Gabryel
The aim of this study was to elucidate body composition, anthropometric indices, and hydration status in obstructive sleep apnea (OSA) patients, taking into account different disease stages, gender, and the possibility of the presence of cachexia. There were 98 OSA patients and 23 control subjects enrolled into the study. All study participants underwent polysomnography examination. Body mass index (BMI), fat mass index (FMI), fat free mass, muscle mass, body cell mass, total body water, and extracellular and intracellular water were evaluated...
March 3, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28236490/does-lymphadenectomy-have-influence-on-postoperative-body-fluid-distribution
#9
Tolgay Tuyan İlhan, Mustafa Gazi Uçar, Aybike Tazegül Pekin, Setenay Arzu Yılmaz, Özlem Seçilmiş Kerimoğlu, Çetin Çelik
OBJECTIVE: We compared the fluid volume parameters in women undergoing gynaecological surgery for benign and malignant conditions before and after surgery using bioelectrical impedance vectors. STUDY DESIGN: A total of 181 patients were enrolled. In all, 89 patients had surgery for benign conditions and 92 patients underwent oncological procedures, including lymph node dissection, for malignant diseases. Bioelectrical impedance analysis (BIA) parameters were measured on the day of hospitalisation before any treatment and at 24h and 1 month after the surgical intervention...
May 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28138765/low-dose-carperitide-%C3%AE-human-a-type-natriuretic-peptide-alleviates-hemoglobin-concentration-decrease-during-prolonged-oral-surgery-a-randomized-controlled-study
#10
Masanori Tsukamoto, Sayuri Koyama, Kanako Esaki, Takashi Hitosugi, Takeshi Yokoyama
PURPOSE: Surgical injury stimulates the renin-angiotensin-aldosterone system (RAAS) and causes antidiuresis, leading to postoperative oliguria. Carperitide (α-human A-type natriuretic peptide) is a cardiac peptide hormone secreted from the atrium. This peptide hormone enhances diuresis by suppressing the RAAS. In our experience, carperitide alleviates decreased hemoglobin (Hb) concentration during elective surgery. In the current study, we investigated the relationship between low-dose carperitide (0...
January 30, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/28093894/importance-of-body-water-in-the-efficacy-of-convective-solute-transport-in-online-hemodiafiltration
#11
Nicolás Macías, Alba Santos García, Almudena Vega Martínez, Soraya Abad Estébanez, Marian Goicoechea Diezhandino, Juan Manuel López Gómez
High-volume online hemodiafiltration (OL-HDF) has been associated with improved patient survival compared to conventional hemodialysis in recent trials, where the importance of convective volume (CV) in this benefit is noted. The purpose of this study was to determine the corporal composition parameters influencing the efficacy of CV in the removal of different molecular weight (MW) molecules. Demographic data, corporal composition parameters with bioimpedance spectroscopy, dialysis features and the reduction rates of different MW molecules in a four-hour OL-HDF session were collected in 61 patients...
February 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28092414/dce-mri-of-the-prostate-using-shutter-speed-vs-tofts-model-for-tumor-characterization-and-assessment-of-aggressiveness
#12
Stefanie J Hectors, Cecilia Besa, Mathilde Wagner, Guido H Jajamovich, George K Haines, Sara Lewis, Ashutosh Tewari, Ardeshir Rastinehad, Wei Huang, Bachir Taouli
PURPOSE: To quantify Tofts model (TM) and shutter-speed model (SSM) perfusion parameters in prostate cancer (PCa) and noncancerous peripheral zone (PZ) and to compare the diagnostic performance of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to Prostate Imaging and Reporting and Data System (PI-RADS) classification for the assessment of PCa aggressiveness. MATERIALS AND METHODS: Fifty PCa patients (mean age 60 years old) who underwent MRI at 3...
January 16, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28063504/the-metabolite-beta-aminoisobutyric-acid-and-physical-inactivity-among-hemodialysis-patients
#13
Alessio Molfino, Maria Ida Amabile, Thomas Ammann, Alessio Farcomeni, Luana Lionetto, Maurizio Simmaco, Silvia Lai, Alessandro Laviano, Filippo Rossi Fanelli, Maria Grazia Chiappini, Maurizio Muscaritoli
OBJECTIVE: Physical inactivity is frequent in patients on hemodialysis (HD), and represents a reliable predictor of morbidity and mortality. Beta-aminoisobutyric acid (BAIBA) is a contraction-induced myokine, the plasma levels of which increase with exercise and are inversely associated with metabolic risk factors. The aim of this study was to ascertain whether physical inactivity and clinical parameters relate to plasma BAIBA levels in this patient population. METHODS: Adult patients on HD were included, and the presence of physical inactivity was assessed...
February 2017: Nutrition
https://www.readbyqxmd.com/read/28046833/su-f-j-155-evaluation-of-transcytolemmal-water-exchange-analysis-for-therapeutic-response-assessment-using-dynamic-contrast-enhanced-mri
#14
C Wang, E Subashi, X Liang, F Yin, Z Chang
PURPOSE: To compare the performance of shutter-speed(SS) model with transcytolemmal water exchange analysis against the Tofts model in the study of the efficacy of an anti-angiogenesis drug METHODS: 16 mice with LS-174T implanted were randomly assigned into treatment/control groups (n=8/group) and received bevacizumab/saline three times (Day1/Day4/Day8). All mice received one pre- (Day0) and two post-treatment (Day2/Day9) DCE scans. For each scan, the CA extravasation rate constant KT(trans) /KS(trans) from the Tofts/SS model were calculated...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27998974/xylem-diameter-changes-during-osmotic-stress-desiccation-and-freezing-in-pinus-sylvestris-and-populus-tremula
#15
Anna Lintunen, Lauri Lindfors, Eero Nikinmaa, Teemu Hölttä
Trees experience low apoplastic water potential frequently in most environments. Low apoplastic water potential increases the risk of embolism formation in xylem conduits and creates dehydration stress for the living cells. We studied the magnitude and rate of xylem diameter change in response to decreasing apoplastic water potential and the role of living parenchyma cells in it to better understand xylem diameter changes in different environmental conditions. We compared responses of control and heat-injured xylem of Pinus sylvestris (L...
December 19, 2016: Tree Physiology
https://www.readbyqxmd.com/read/27929105/glymphatic-solute-transport-does-not-require-bulk-flow
#16
Mahdi Asgari, Diane de Zélicourt, Vartan Kurtcuoglu
Observations of fast transport of fluorescent tracers in mouse brains have led to the hypothesis of bulk water flow directed from arterial to venous paravascular spaces (PVS) through the cortical interstitium. At the same time, there is evidence for interstitial solute transport by diffusion rather than by directed bulk fluid motion. It has been shown that the two views may be consolidated by intracellular water flow through astrocyte networks combined with mainly diffusive extracellular transport of solutes...
December 8, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27916883/enhanced-autophagy-in-polycystic-kidneys-of-aqp11-null-mice
#17
Yasuko Tanaka, Mayumi Watari, Tatsuya Saito, Yoshiyuki Morishita, Kenichi Ishibashi
Aquaporin-11 (AQP11) is an intracellular water channel expressed at the endoplasmic reticulum (ER) of the proximal tubule. Its gene disruption in mice leads to intracellular vacuole formation at one week and the subsequent development of polycystic kidneys by three weeks. As the damaged proximal tubular cells with intracellular vacuoles form cysts later, we postulated that autophagy may play a role in the cyst formation and examined autophagy activity before and after cyst development in AQP11(-/-) kidneys...
November 30, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27905583/intracellular-water-an-overlooked-drug-target-cisplatin-impact-in-cancer-cells-probed-by-neutrons
#18
M P M Marques, A L M Batista de Carvalho, V Garcia Sakai, L Hatter, L A E Batista de Carvalho
The first neutron scattering study on human nucleated cells is reported, addressing the subject of solvent-slaving to a drug by probing intracellular water upon drug exposure. Inelastic and quasi-elastic neutron scattering spectroscopy with isotope labelling was applied for monitoring interfacial water response to the anticancer drug cisplatin, in the low prognosis human metastatic breast cancer cells MDA-MB-231. Optical vibrational data were also obtained for lyophilised cells. Concentration-dependent dynamical changes evidencing a progressive mobility reduction were unveiled between untreated and cisplatin-exposed samples, concurrent with variations in the native organisation of water molecules within the intracellular medium as a consequence of drug action...
December 1, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27866102/variations-in-physical-chemical-and-biological-properties-in-relation-to-sludge-dewaterability-under-fe-ii-oxone-conditioning
#19
Keke Xiao, Yun Chen, Xie Jiang, Qin Yang, Wan Yi Seow, Wenyu Zhu, Yan Zhou
The mechanism of Fe (II) - oxone conditioning to improve sludge dewaterability was investigated in this study. Five different types of sludge were tested, including raw sludge (Group 1: mixed primary and secondary sludge, waste activated sludge and anaerobic digested sludge) and pretreated sludge with prior solubilisation (Group 2: ultrasonic or thermal pretreated sludge). After Fe (II) - oxone conditioning, the concentrations of dissolved organic carbon, protein and polysaccharide of soluble extracellular polymeric substances (SB EPS) increased for Group 1, but decreased for Group 2...
February 1, 2017: Water Research
https://www.readbyqxmd.com/read/27853064/impact-of-the-8-week-administration-of-tofogliflozin-for-glycemic-control-and-body-composition-in-japanese-patients-with-type-2-diabetes-mellitus
#20
Sachie Hirose, Shinsuke Nakajima, Yasuyuki Iwahashi, Akane Seo, Tetsuya Takahashi, Yoshikazu Tamori
Objective The adverse effects of selective sodium-glucose co-transporter 2 (SGLT2) inhibitors generally appear within about two or three months after treatment initiation in Japan. Therefore, we investigated the impact of tofogliflozin, a class of SGLT2 inhibitors, on glycemic control and body composition during this period in Japanese patients with type 2 diabetes mellitus. Methods This single-arm open-label study enrolled 20 patients. Patients received tofogliflozin 20 mg once daily for 8 weeks. At week 8, changes from baseline in body weight, serum metabolic markers, and body composition were evaluated...
2016: Internal Medicine
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