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https://www.readbyqxmd.com/read/28877246/prosthetic-rehabilitation-of-oral-submucous-fibrosis-patients-a-systematic-review-of-published-case-reports-and-case-series
#1
Shankargouda Patil, Sachin Chakradhar Sarode, Gargi S Sarode, Shilpa Bhandi, Kamran Habib Awan, Marco Ferrari
BACKGROUND: Oral submucous fibrosis (OSF) is an insidious chronic condition characterized by restricted mouth opening. Prosthetic rehabilitation is challenging for OSF patients as obtaining a good impression requires adequate mouth opening. The aim of the present review is to systematically present the data from case reports published in the English-language literature. METHOD: A comprehensive search of the literature databases (PubMed, Medline, SCOPUS, Web of Science and Google Scholar) along with the references of published articles on prosthetic rehabilitation in OSF patients published to date was conducted...
2017: PloS One
https://www.readbyqxmd.com/read/28861457/data-and-material-of-the-safe-range-inventory-an-assistance-tool-helping-to-improve-the-charging-infrastructure-for-electric-vehicles
#2
Claus-Christian Carbon, Fabian Gebauer
The Safe-Range-Inventory (SRI) was constructed in order to help public authorities to improve the charging infrastructures for electric vehicles [1; 10.1016/j.trf.2017.04.011]. Specifically, the impact of fast (vs slow) charging stations on people's range anxiety was examined. Ninety-seven electric vehicle users from Germany (81 male; Mage=46.3 years, SD=12.1) were recruited to participate in the experimental design. Statistical analyses were conducted using ANOVA for repeated measures to test for interaction effects of available charging stations and remaining range with the dependent variable range anxiety...
October 2017: Data in Brief
https://www.readbyqxmd.com/read/28855201/intersectoral-approaches-and-integrated-services-in-achieving-the-right-to-health-for-refugees-upon-resettlement-a-scoping-review-protocol
#3
Dena Javadi, Etienne V Langlois, Shirley Ho, Peter Friberg, Göran Tomson
INTRODUCTION: Global insecurity and climate change are exacerbating the need for improved management of refugee resettlement services. International standards hold states responsible for the protection of the right of non-citizens to an adequate standard of physical and mental health while recognising the importance of social determinants of health. However, programmes to protect refugees' right to health often lack coordination and monitoring. This paper describes the protocol for a scoping review to explore barriers and facilitators to the integration of health services for refugees; the content, process and actors involved in protecting refugee health; and the extent to which intersectoral approaches are leveraged to protect refugees' right to health on resettlement, especially for vulnerable groups such as women and children...
August 30, 2017: BMJ Open
https://www.readbyqxmd.com/read/28853214/long-term-evaluation-of-osteotome-sinus-floor-elevation-and-simultaneous-placement-of-implants-without-bone-grafts-10-year-radiographic-and-clinical-follow-up
#4
Janusz Caban, Robert Fermergård, Jahan Abtahi
BACKGROUND: Insertion of an implant in the edentulous posterior maxilla is a challenging procedure because of poor bone quality and increased pneumatization of the maxillary sinus after tooth extraction. To increase the amount of bone, several surgical bone grafting techniques have been used-with considerable morbidity for patients. Osteotome sinus floor elevation (OSFE) is a less invasive technique. The clinical and radiographic outcome of 53 implants placed with this technique without bone graft has been reported previously...
August 29, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28821582/identification-of-%C3%AE-enolase-as-a-prognostic-and-diagnostic-precancer-biomarker-in-oral-submucous-fibrosis
#5
Swarnendu Bag, Debabrata Dutta, Amrita Chaudhary, Bidhan Chandra Sing, Mousumi Pal, Ajoy Kumar Ray, Rita Banerjee, Ranjan Rashmi Paul, Amit Basak, Amit Kumar Das, Jyotirmoy Chatterjee
AIMS: Diagnostic ambiguities regarding the malignant potentiality of oral submucous fibrosis (OSF), an oral precancerous condition having dysplastic and non-dysplastic isoforms are the major failure for early intervention of oral squamous cell carcinoma (OSCC) patients. Our goal is to identify proteomic signatures from biopsies that can be used as precancer diagnostic marker for patient suffering from OSF. METHODS: The high throughput techniques adopting de novo peptide sequencing (1D SDS-PAGE coupled nanoLC MALDI tandem mass spectrometry (MS/MS)-based peptide mass fingerprint), immunohistochemistry (IHC), Western blot (WB) and real-time PCR (RT-PCR) analysis are considered for such biomarker identification and multilevel validations...
August 18, 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28816025/aromatic-interactions-at-the-ligand-protein-interface-implications-for-the-development-of-docking-scoring-functions
#6
Michal Brylinski
The ability to design and fine-tune non-covalent interactions between organic ligands and proteins is indispensable to rational drug development. Aromatic stacking has long been recognized as one of the key constituents of ligand-protein interfaces. In this communication, we employ a two-parameter geometric model to conduct a large-scale statistical analysis of aromatic contacts in the experimental and computer-generated structures of ligand-protein complexes, considering various combinations of aromatic amino acid residues and ligand rings...
August 17, 2017: Chemical Biology & Drug Design
https://www.readbyqxmd.com/read/28815252/-expression-of-ptprz1-in-oral-squamous-cell-carcinoma-originated-from-oral-submucous-fibrosis-and-its-clinical-significance
#7
Rong Zhu, Xin-Chun Jian, De-Yu Liu, Chao Zhou, Yuan Wang
PURPOSE: This study was aimed to detect the expression of PTPRZ1 in oral squamous cell carcinoma (OSCC) originated from oral submucous fibrosis (OSF), and discuss its role in the development and progression of OSCC originating from OSF as well as its clinical significance. METHODS: Immunohistochemisty (IHC) and Western blot (WB) for the expression and distribution of PTPRZ1 were carried out in 36 cases of OSF transforming into OSCC, 23 cases of OSCC and 21 cases of healthy controls...
April 2017: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/28803085/palliative-care-in-south-africa
#8
Cornelia Drenth, Zodwa Sithole, Esme Pudule, Sheryl Wüst, Nicola GunnClark, Liz Gwyther
The Hospice Palliative Care Association (HPCA) was established in 1987 by hospices in South Africa who felt the need for a national body to share best practices and to promote palliative care services in South Africa. HPCA supports member hospices in providing palliative care to people of any age with a life-limiting condition. HPCA has the further aim to ensure access to palliative care in settings other than member hospices. Many projects were launched over the years to influence policy, and to educate medical practitioners, nurses, social workers, theologians, and community caregiver; and to develop services...
August 9, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28797860/palliative-care-for-tuberculosis
#9
Stephen R Connor
In 2014, 1.5 million people died of tuberculosis (TB) worldwide including 400,000 co-infected with HIV. TB remains a major cause of death and suffering globally, in spite of the fact that it is supposed to be a curable disease. Drug resistant forms of TB have developed as a result of poor treatment compliance including multi-drug and extreme drug resistant forms that take longer to treat and have higher likelihoods of treatment failure. In 2010, at the initiation of the TB community, a partnership was formed between the WHO Stop TB Program, the Worldwide Hospice Palliative Care Alliance, and the Open Society Foundation's International Palliative Care Initiative (OSF/IPCI) to explore how to improve the ability of TB professionals to deliver palliative care to their patients...
August 7, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28797853/european-association-for-palliative-care-forging-a-vision-of-excellence-in-palliative-care-in-central-and-eastern-european-and-former-sovjet-union-countries-cee-fsu
#10
Lukas Radbruch, Julie Ling, Katalin Hegedus, Philip Larkin
The European Association for Palliative Care (EAPC) represents many thousands of health care workers and volunteers working in or with an interest in palliative care. In 2016, the EAPC has individual members from 48 nations across the world, and collective members from 57 national palliative care associations in 32 European Countries. Throughout its history, the EAPC has produced guidance on a range of palliative care issues. The biennial congresses and research congresses and the comprehensive website (www...
August 7, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28781930/coronal-and-heliospheric-magnetic-flux-circulation-and-its-relation-to-open-solar-flux-evolution
#11
Mike Lockwood, Mathew J Owens, Suzanne M Imber, Matthew K James, Emma J Bunce, Timothy K Yeoman
Solar cycle 24 is notable for three features that can be found in previous cycles but which have been unusually prominent: (1) sunspot activity was considerably greater in the northern/southern hemisphere during the rising/declining phase; (2) accumulation of open solar flux (OSF) during the rising phase was modest, but rapid in the early declining phase; (3) the heliospheric current sheet (HCS) tilt showed large fluctuations. We show that these features had a major influence on the progression of the cycle...
June 2017: Journal of Geophysical Research. Space Physics
https://www.readbyqxmd.com/read/28767421/periostin-promotes-epithelial-mesenchymal-transition-via-the-mapk-mir-381-axis-in-lung-cancer
#12
Wei-Wei Hu, Po-Chun Chen, Jun-Ming Chen, Yue-Ming Wu, Po-Yi Liu, Chih-Hao Lu, Yu-Feng Lin, Chih-Hsin Tang, Chia-Chia Chao
Periostin (POSTN, PN, or osteoblast-specific factor OSF-2) is a multifunctional cytokine that signals between the cell and the extracellular matrix. Periostin plays an important role in tumor development and is involved in carcinoma cell epithelial-mesenchymal transition (EMT), whereby mature epithelial cells undergo phenotypic morphological changes and become invasive, motile cells. Here, we discuss the molecular mechanisms involved in periostin-induced promotion of EMT in lung cancer cells. Online TCGA datasets demonstrate the prognostic relevance of periostin in lung cancer; a higher periostin level correlates with poor overall survival...
July 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28766765/impact-of-oral-potentially-malignant-disorders-on-quality-of-life
#13
Jyothi Tadakamadla, Santhosh Kumar, Ratilal Lalloo, Gandhi Babu, Newell W Johnson
BACKGROUND: Oral Potentially Malignant Disorders (OPMDs) could have a significant psychological impact on patients, principally because of the unknown risk of malignant transformation, while the physical and functional impairments could differ. This study aimed to assess the impact of three different OPMDs and their disease stages on the Quality of Life (QoL) of affected patients. METHODS: Oral Leukoplakia (OL), Oral Lichen Planus (OLP) and Oral Submucous Fibrosis (OSF) patients who were undergoing treatment at an oral medicine clinic of a dental teaching hospital in India were the study population...
August 2, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28720506/arecoline-activates-latent-transforming-growth-factor-%C3%AE-1-via-mitochondrial-reactive-oxygen-species-in-buccal-fibroblasts-suppression-by-epigallocatechin-3-gallate
#14
Yu-Ping Hsieh, King-Jean Wu, Hsin-Ming Chen, Yi-Ting Deng
BACKGROUND/PURPOSE: Oral submucous fibrosis (OSF) is a premalignant condition caused by the chewing of areca nut (AN). Transforming growth factor β (TGFβ) plays a central role in the pathogenesis of OSF. Connective tissue growth factor (CTGF or CCN2) and early growth response-1 (Egr-1) are important mediators in the fibrotic response to TGFβ in several fibrotic disorders including OSF. Arecoline, a major AN alkaloid, induced the synthesis of CCN2 and Egr-1 in human buccal mucosal fibroblast (BMFs)...
July 15, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28713656/methodological-considerations-in-assessment-of-language-lateralisation-with-fmri-a-systematic-review
#15
Abigail R Bradshaw, Dorothy V M Bishop, Zoe V J Woodhead
The involvement of the right and left hemispheres in mediating language functions has been measured in a variety of ways over the centuries since the relative dominance of the left hemisphere was first known. Functional magnetic resonance imaging (fMRI) presents a useful non-invasive method of assessing lateralisation that is being increasingly used in clinical practice and research. However, the methods used in the fMRI laterality literature currently are highly variable, making systematic comparisons across studies difficult...
2017: PeerJ
https://www.readbyqxmd.com/read/28680630/burden-and-health-related-quality-of-life-of-eating-disorders-including-avoidant-restrictive-food-intake-disorder-arfid-in-the-australian-population
#16
Phillipa Hay, Deborah Mitchison, Abraham Ernesto Lopez Collado, David Alejandro González-Chica, Nigel Stocks, Stephen Touyz
BACKGROUND: Little is known about the epidemiology and health related quality of life (HRQoL) of the new DSM-5 diagnoses, Binge Eating Disorder (BED) and Avoidant/Restrictive Food Intake Disorder (ARFID) in the Australian population. We aimed to investigate the prevalance and burden of these disorders. METHODS: We conducted two sequential population-based surveys including individuals aged over 15 years who were interviewed in 2014 (n = 2732) and 2015 (n =3005)...
2017: Journal of Eating Disorders
https://www.readbyqxmd.com/read/28630826/predicting-the-effects-of-interventions-a-tutorial-on-the-disequilibrium-model
#17
Kenneth W Jacobs, Zachary H Morford, James E King, Linda J Hayes
The disequilibrium approach to reinforcement and punishment, derived from the probability-differential hypothesis and response deprivation hypothesis, provides a number of potentially useful mathematical models for practitioners. The disequilibrium approach and its accompanying models have proven effective in the prediction and control of behavior, yet they have not been fully espoused and integrated into clinical practice. The purpose of this tutorial is to detail the disequilibrium approach and adapt its mathematical models for use as a tool in applied settings...
June 2017: Behavior Analysis in Practice
https://www.readbyqxmd.com/read/28629337/validity-and-reliability-of-electroacoustic-probe-for-diagnosis-of-developmental-dysplasia-of-the-hip
#18
Nicolas Padilla-Raygoza, Georgina Olvera-Villanueva, Silvia Del Carmen Delgado-Sandoval, Teodoro Cordova-Fraga, Modesto Antonio Sosa-Aquino, Vicente Beltran-Campos
BACKGROUND: Sound transmission is used in the diagnosis of hip dysplasia since the end of the 80's. Aim of this study is to quantify the validity and reliability of electroacoustic probe for the diagnosis of hip dysplasia in neonates. METHODS: Diagnostic study included neonates aged 4-28 days, whose parents signed an informed consent. The probe was used three times for comparative sound transmission and with extension/flexion; hip ultrasound was performed with Graf technique as gold standard...
June 19, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28592334/impact-of-oocyte-secreted-factors-on-its-developmental-competence-in-buffalo
#19
Swati Gupta, Sriti Pandey, Mehtab S Parmar, Anjali Somal, Avishek Paul, Bibhudatta S K Panda, Irfan A Bhat, Indu Baiju, Mukesh K Bharti, G Saikumar, Mihir Sarkar, Vikash Chandra, G Taru Sharma
Oocyte-secreted factors (OSFs) play an important role in the acquisition of oocyte developmental competence through bidirectional cross-talk between oocyte and cumulus cells via gap junctions. Thus, the present study was designed to investigate the effect of two OSFs, growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15), on the developmental competence of buffalo oocytes derived from two different follicle sizes. Cumulus-oocyte complexes (COCs) from large follicles (LF, >6 mm) or small follicles (SF, 0...
June 2017: Zygote: the Biology of Gametes and Early Embryos
https://www.readbyqxmd.com/read/28580647/diagnosis-specific-self-image-predicts-longitudinal-suicidal-ideation-in-adult-eating-disorders
#20
Mikael Andersén, Andreas Birgegård
OBJECTIVE: Eating disorders (ED) are prevalent, serious illnesses with elevated mortality, mainly attributable to suicide. Predictors of suicidality include binge/purge symptomatology, impulsivity, and psychiatric comorbidity, as well as personality factors. Recent research has also shown self-image (the Structural Analysis of Social Behavior, SASB, model) to predict manifest suicide attempts in ED, and the study explored suicide risk prediction to increase knowledge of warning signs and intervention targets...
August 2017: International Journal of Eating Disorders
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