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https://www.readbyqxmd.com/read/29329525/reporting-of-heterogeneity-of-treatment-effect-in-cohort-studies-a-review-of-the-literature
#1
Meryl Dahan, Caroline Scemama, Raphael Porcher, David J Biau
BACKGROUND: This article corresponds to a literature review and analyze how heterogeneity of treatment (HTE) is reported and addressed in cohort studies and to evaluate the use of the different measures to HTE analysis. METHODS: prospective cohort studies, in English language, measuring the effect of a treatment (pharmacological, interventional, or other) published among 119 core clinical journals (defined by the National Library of Medicine) in the last 16 years were selected in the following data source: Medline...
January 12, 2018: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/29328443/-retracted-effects-of-cyclin-e-gene-silencing-on-the-proliferation-of-esophageal-cancer-cell-lines-ec9706-eca109-and-kyse30
#2
Na Wang, Min Li, Wen-Qiao Zang, Yun-Yun Ma, Yuan-Yuan Wang, Guo-Qiang Zhao
Subsequently to the publication of this article, an interested reader drew to our attention the fact that the six panels shown in Fig. 6 shared several areas of identity among them. Following an internal investigation, a laboratory technician, who was responsible for editing the pictures, admitted that the data as presented in the figure had been manipulated after having mislaid some of the original data. The corresponding author of the article takes responsibility for this oversight, and therefore the paper is to be retracted from publication...
January 9, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29316880/structure-formats-of-randomised-controlled-trial-abstracts-a-cross-sectional-analysis-of-their-current-usage-and-association-with-methodology-reporting
#3
Fang Hua, Tanya Walsh, Anne-Marie Glenny, Helen Worthington
BACKGROUND: The reporting of randomised controlled trial (RCT) abstracts is of vital importance. The primary objective of this study was to investigate the association between structure format and RCT abstracts' quality of methodology reporting, informed by the current requirement and usage of structure formats by leading general medical/internal medicine journals (secondary objective). METHODS: A two-part cross-sectional study. First, through hand searches, we identified all RCTs published in the top-50 high-impact general medical/internal medicine journals during July-December 2015 (n = 370), and retrieved the 'instructions to authors' of these journals...
January 10, 2018: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/29309169/-journal-amha-acta-medico-historica-adriatica-14-years-of-patient-work-on-the-scientific-valorisation-of-the-history-of-medicine
#4
Igor Eterović
In this paper the first 14 years of publication of scientific journal AMHA - Acta medico‑historica Adriatica (2002-2016) are presented and shortly analysed. This journal has undoubtedly become and remained the central activity of the Croatian Scientific Society for the History of Health Culture, which has rapidly become a globally esteemed journal of history of medicine. The beginning and the context of publishing the journal with the reference to scientific meeting "Rijeka and Its Citizens in Medical History" is presented, as well as the journal's profiling into distinguished international journal and its fast development in later years...
December 2017: Acta Medico-historica Adriatica: AMHA
https://www.readbyqxmd.com/read/29309167/-on-the-occasion-of-the-fiftieth-anniversary-of-the-croatian-scientific-society-for-the-history-of-health-culture
#5
Ante Škrobonja, Igor Salopek
A group of intellectuals, predominantly lecturers from the Faculty of Medicine, founded in Rijeka on May 29, 1966 the branch of the Yugoslav Scientific Society for the History of Health Culture, which after the independence of Croatia in 1991 continues its work under the name Croatian Scientific Society for the History of Health Culture. Over the past 50 years, within activities of the Society more than 250 professional and scientific conferences have been held in Rijeka and other Croatian cities. In addition, a dozen of professional-scientific trips to neighbouring countries were organized...
December 2017: Acta Medico-historica Adriatica: AMHA
https://www.readbyqxmd.com/read/29302729/color-change-after-paramedical-pigmentation-of-the-nipple-areola-complex
#6
Shoichi Tomita, Katsuya Mori, Takeshi Miyawaki
BACKGROUND: Reconstruction of the nipple-areola complex is the final process in breast reconstruction. Local flaps and paramedical pigmentation is one of the major procedures for this. However, fading after paramedical pigmentation leads to a color difference between the selected pigment and its color in the skin. The aim of this study is to make a proposition in color choice of paramedical pigmentation for nipple-areola complex. METHODS: Our research focused on investigating the color changes over time after unilateral nipple-areola complex reconstruction using paramedical pigmentation in 25 patients to propose suitable color selections...
January 4, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29298301/mapping-of-global-scientific-research-in-comorbidity-and-multimorbidity-a-cross-sectional-analysis
#7
Ferrán Catalá-López, Adolfo Alonso-Arroyo, Matthew J Page, Brian Hutton, Rafael Tabarés-Seisdedos, Rafael Aleixandre-Benavent
BACKGROUND: The management of comorbidity and multimorbidity poses major challenges to health services around the world. Analysis of scientific research in comorbidity and multimorbidity is limited in the biomedical literature. This study aimed to map global scientific research in comorbidity and multimorbidity to understand the maturity and growth of the area during the past decades. METHODS AND FINDINGS: This was a cross-sectional analysis of the Web of Science...
2018: PloS One
https://www.readbyqxmd.com/read/29282262/brain-health-and-healthy-ageing-in-retired-rugby-union-players-the-brain-study-study-protocol-for-an-observational-study-in-the-uk
#8
Valentina Gallo, Damien McElvenny, Catherine Hobbs, Donna Davoren, Huw Morris, Sebastian Crutch, Henrik Zetterberg, Nick C Fox, Simon Kemp, Matthew Cross, Nigel K Arden, Madeleine A M Davies, Andrea Malaspina, Neil Pearce
INTRODUCTION: Relatively little is known about the long-term health of former elite rugby players, or former sportspeople more generally. As well as the potential benefits of being former elite sportspersons, there may be potential health risks from exposures occurring during an individual's playing career, as well as following retirement. Each contact sport has vastly different playing dynamics, therefore exposing its players to different types of potential traumas. Current evidence suggests that these are not necessarily comparable in terms of pathophysiology, and their potential long-term adverse effects might also differ...
December 26, 2017: BMJ Open
https://www.readbyqxmd.com/read/29281975/a-survey-of-prevalence-of-narrative-and-systematic-reviews-in-five-major-medical-journals
#9
Clovis Mariano Faggion, Nikolaos P Bakas, Jason Wasiak
BACKGROUND: Systematic reviews may provide less biased evidence than narrative reviews because they observe a strict methodology, similarly to primary studies. Hence, for clinical research questions, systematic reviews should be the study design of choice. It would be important to evaluate the prevalence and characteristics of narrative and systematic reviews published in prominent medical journals. Researchers and clinicians give great value to articles published in such scientific journals...
December 28, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/29273932/treatment-of-gigantomastia-using-a-medial-lateral-bipedicle-reduction-mammoplasty-the-role-of-doppler-assisted-preoperative-perforator-identification
#10
Nader Gomaa Elmelegy, Mohamed Saad Sadaka, Ahmed M Hegazy, Doaa E Abdeldaim
The purpose of this study is to introduce a breast reduction technique designed to reduce the incidence of postoperative nipple-areola complex ischemia and necrosis following reduction mammoplasty, while at the same time allowing all the other goals of breast reduction to be realized. This is achieved through preoperative detection of perforating vessels supplying the nipple-areola complex using a hand-held Doppler. The horizontally based parenchymal pedicle is designed to include these perforators whether originating from the internal mammary artery, lateral thoracic artery or both...
December 22, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29261360/precision-medicine-functional-advancements
#11
Thomas Caskey
Precision medicine was conceptualized on the strength of genomic sequence analysis. High-throughput functional metrics have enhanced sequence interpretation and clinical precision. These technologies include metabolomics, magnetic resonance imaging, and I rhythm (cardiac monitoring), among others. These technologies are discussed and placed in clinical context for the medical specialties of internal medicine, pediatrics, obstetrics, and gynecology. Publications in these fields support the concept of a higher level of precision in identifying disease risk...
December 20, 2017: Annual Review of Medicine
https://www.readbyqxmd.com/read/29249246/-what-s-new-in-clinical-dermatology
#12
A Petit
In addition to continuous medical education, medical journals offer to dermatologists a huge variety of news that differ by their content, validity, originality and clinical relevance. I collected here various articles relative to clinical dermatology that have been published between September, 2016 and September, 2017. These papers have been chosen in the aim of reflecting such diversity. I just excluded, as far as possible, articles dealing with other issues that the reader will find further in this booklet (such as research, pediatric, instrumental, oncologic or therapeutic dermatology, or dermatology and internal medicine)...
December 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/29237141/lessons-from-the-barn-to-the-operating-suite-a-comprehensive-review-of-animal-models-for-fetal-surgery
#13
Sandra K Kabagambe, Chelsey J Lee, Laura F Goodman, Y Julia Chen, Melissa A Vanover, Diana L Farmer
The International Fetal Medicine and Surgery Society was created in 1982 and proposed guidelines for fetal interventions that required demonstrations of the safety and feasibility of intended interventions in animal models prior to application in humans. Because of their short gestation and low cost, small animal models are useful in early investigation of fetal strategies. However, owing to the anatomic and physiologic differences between small animals and humans, repeated studies in large animal models are usually needed to facilitate translation to humans...
December 13, 2017: Annual Review of Animal Biosciences
https://www.readbyqxmd.com/read/29234856/modified-island-technique-for-prominent-ears
#14
Horacio F Mayer, Hugo D Loustau
There have been several methods described for the correction of prominent ears, including techniques that excise, bend, suture, score, or cut the auricular cartilage. The Island Technique, proposed by Pitanguy, is based on the creation of a cartilage island to define the antihelix and correct the conchoscaphal angle. Visibility of sharp edges has been the main criticism of this technique. To avoid them, we advise performing an internal bevel incision to round off the edges and achieve a more natural look. Also, sometimes prominent ears are asymmetric with different conchoscaphal angles, determining a residual but protruding upper pole, thus requiring different treatment on each side...
December 12, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29234711/a-study-of-the-number-of-female-editors-in-chief-of-dermatology-journals
#15
C E Gollins, A R Shipman, D F Murrell
Introduction: Over the past 50 years the proportion of women entering medical school has vastly increased, however there still exists a gender gap in top leadership positions, including within academic medicine. It is important to investigate the influence of women in this area, and assess change over time. The aim of the study was to assess the number of women who have acted as editors-in-chief of prominent dermatology journals over the 20th and 21st centuries. Methods: A list of 25 journals was collated based on their impact factors and prominence...
December 2017: International Journal of Women's Dermatology
https://www.readbyqxmd.com/read/29231446/-the-indications-of-acupuncture-moxibustion-in-china-state-compiled-textbooks
#16
Weijuan Gang, Xiaodong Wu, Fang Wang, Xin Wang
The Acupuncture-moxibustion and Acupuncture-moxibustion therapy have been the state-compiled textbooks of acupuncture-moxibustion in colleges and universities of TCM for nearly more than half a century, which play a regulating and guiding role for acupuncture education and to a certain extent represent the development status of this discipline. The indications included in Acupuncture-moxibustion from 1th edition to 7th edition and Acupuncture-moxibustion therapy from 1th edition to 3rd edition were analyzed in this study, which was aimed to basically reflect the current situation of acupuncture indications...
March 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29214336/the-efficacy-and-safety-of-early-postoperative-botulinum-toxin-a-injection-for-facial-scars
#17
Seo H Lee, Hyung J Min, Yang W Kim, Young W Cheon
BACKGROUND: Scars widen when the underlying musculature pulls apart suture lines, and scars oriented against relaxed skin tension lines are especially susceptible to these distraction forces. Because botulinum toxin A (BTA) induces complete muscle paralysis, the purpose of the current study was to evaluate the effects of BTA using both observer-dependent qualitative assessments and quantitative measurements to verify its beneficial effects on facial scarring. METHODS: Patients with vertical forehead lacerations, treated by primary closure, were randomly assigned to two groups: one (n = 15) received BTA injections within 5 days of primary closure and the other (n = 15) received no further treatment...
December 6, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29203748/international-legal-regulation-of-impact-of-occupational-injuries-and-diseases-on-agricultural-workers-health
#18
Vitalii M Pashkov, Olena M Batyhina, Maryna V Trotska
INTRODUCTION: Agricultural workers' health depends on many factors: working conditions, security arrangements, medicine, quality of drugs, the environment, etc. Occupational injuries and diseases are also among the factors that can negatively affect their health. THE AIM: To analyze provisions of the international legislation and scientific literature concerning existence of restrictions on impact of occupational injuries and diseases on agricultural workers' health...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29196484/effect-of-herbal-extract-granules-combined-with-otilonium-bromide-on-irritable-bowel-syndrome-with-diarrhoea-a-study-protocol-for-a-randomised-controlled-trial
#19
Joong Il Kim, Pumsoo Kim, Jin-Hyun Lee, Yoo-Jin Kim, Na-Rae Yang, Myong Ki Baeg, Ja Sung Choi, Hye-Jung Kim, Jayoung Kim, Yun-Young Sunwoo, Jung-Han Lee, Hyekyung Ha, Tae-Yong Park
INTRODUCTION: Irritable bowel syndrome (IBS), known as a functional and organic gastrointestinal disorder, is a collection of symptoms that occur together and generally include pain or discomfort in the abdomen and changes in bowel movement patterns. Due to the limitations of conventional treatments, alternative IBS treatments are used by many patients worldwide. Samryungbaekchulsan (SRS), a herbal formula, has long been used for alleviating diarrhoea-predominant IBS (D-IBS) in traditional Korean medicine...
December 1, 2017: BMJ Open
https://www.readbyqxmd.com/read/29190142/biomedical-science-undergraduate-major-a-new-pathway-to-advance-research-and-the-health-professions
#20
John S Gunn, Cynthia H Ledford, Steven J Mousetes, Michael R Grever
PROBLEM: Many students entering professional degree programs, particularly M.D., Ph.D., and M.D./Ph.D., are not well prepared regarding the breadth of scientific knowledge required, communication skills, research experience, reading and understanding the scientific literature, and significant shadowing (for M.D.-related professions). In addition, physician scientists are a needed and necessary part of the academic research environment but are dwindling in numbers. INTERVENTION: In response to predictions of critical shortages of clinician investigators and the lack of proper preparation as undergraduates for these professions, the Biomedical Science (BMS) undergraduate major was created at The Ohio State University to attract incoming college freshmen with interests in scientific research and the healthcare professions...
November 30, 2017: Teaching and Learning in Medicine
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