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JOURNAL ARTICLE
Shu Xu, William M Jesdale, Catherine E Dubé, Natalia N Nielsen, Emily A McPhillips, Kate L Lapane
BACKGROUND AND OBJECTIVES: Using US national nursing home data, this cross-sectional study sought to evaluate 1) the association between lack of social engagement and level of cognitive impairment; and 2) the extent to which this association differs by hearing and visual impairment. RESEARCH DESIGN AND METHODS: Our sample included 793,846 nursing home residents aged ≥ 50 years. The Index of Social Engagement was categorized as none/lower (0, 1, 2) or higher levels (3 through 6)...
March 5, 2024: Archives of Gerontology and Geriatrics
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JOURNAL ARTICLE
Yahya Pasdar, Shahab Rezaeian, Ehsan Mohammadi, Fatemeh Khosravi Shadmani, Narges Shahnazi, Farid Najafi, Mehdi Moradi Nazar, Mitra Darbandi
BACKGROUND: Interactions between risk factors may influence disease severity. Knowing this relationship is important for preventive interventions and disease control. The purpose of this study was to determine the interactions effects of obesity and hypertension on the risk of type 2 diabetes mellitus (T2DM). METHODS: The data of 9,283 adults 35 to 65 years were examined from the cohort study of Ravansar Non-Communicable Disease (RaNCD). Waist circumference (WC) was used to identify both general and abdominal obesity based on body mass index (BMI)...
March 11, 2024: BMC Public Health
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JOURNAL ARTICLE
Wyke Kusmasari, Auditya Purwandini Sutarto, Nugrahaning Sani Dewi, Yassierli, Titah Yudhistira, Khoirul Muslim, Kadek Heri Sanjaya, Aridhotul Haqiyah, Wahyu Dwi Lestari
OBJECTIVE: Construction workers are significantly vulnerable to musculoskeletal disorders, yet the number of studies conducted in developing nations-where these workers significantly contribute to the economy-remains insufficient. This study aims at exploring the interaction between physical and psychosocial exposure to the onset of neck pain or symptoms amongst construction workers in a developing country. METHODS: Using a cross-sectional study design, a total of 235 respondents from various construction projects participated in this study...
March 5, 2024: Journal of Occupational Health
#24
JOURNAL ARTICLE
Linmin Hu, Siqing Wu, Yunhui Zhang, Xuedan Xia, Yuelong Shu, Qiangsheng He, Huang Manshan, Zicong Kuo, Yingya Zhao, Pengpeng Wang, Yanfei Li, Chunliang Wang, Kai Su, Hengyi Han, Jinqiu Yuan, Jianbang Xiang, Bin Xia
OBJECTIVES: The aim of this study was to evaluate the individual and combined effects of maternal smoking during pregnancy (MSDP) and personal smoking on mortality and life expectancy. STUDY DESIGN: A prospective cohort study based on the UK Biobank, with a median follow-up of 12.47 years. METHODS: This study employed multivariate Cox regression to determine the relative risks of mortality from all causes and specific diseases according to maternal and/or personal smoking status and pack-years of smoking (0, 1-20, 21-30, >30)...
March 4, 2024: Public Health
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JOURNAL ARTICLE
Roger Keller Celeste, Antonio Fernando Boing, Karen Glazer Peres, Marco Aurelio Peres
OBJECTIVES: To evaluate the extent to which dental care factors in adulthood modify and, at the same time, mediate the association between race/ethnicity and social mobility from childhood to adulthood with two oral health outcomes in adults. METHODS: In 2012, 1222 individuals 20-59 years old participated in the second wave of the Epi-Floripa Study in Florianopolis, Brazil. Exposures included social mobility based on adulthood and childhood events, dental care in previous years, type of dental care coverage, reason for dental visits and race...
March 4, 2024: Oral Diseases
#26
JOURNAL ARTICLE
Otavio Ranzani, Anna Alari, Sergio Olmos, Carles Milà, Alex Rico, Xavier Basagaña, Payam Dadvand, Talita Duarte-Salles, Francesco Forastiere, Mark Nieuwenhuijsen, Rosa M Vivanco-Hidalgo, Cathryn Tonne
OBJECTIVE: Factors that shape individuals' vulnerability to the effects of air pollution on COVID-19 severity remain poorly understood. We evaluated whether the association between long-term exposure to ambient NO2 , PM2.5 , and PM10 and COVID-19 hospitalisation differs by age, sex, individual income, area-level socioeconomic status, arterial hypertension, diabetes mellitus, and chronic obstructive pulmonary disease. METHODS: We analysed a population-based cohort of 4,639,184 adults in Catalonia, Spain, during 2020...
February 23, 2024: Environment International
#27
JOURNAL ARTICLE
Jiamin Cao, Jun Li, Zuofeng Zhang, Guoyou Qin, Yi Pang, Mengyin Wu, Kai Gu, Huilin Xu
Both body mass index (BMI) and family history of cancer are established risk factors for female breast cancer. However, few studies explored the potential interaction between both factors. We assessed the association of BMI and its interaction with family cancer history on the risk of female breast cancer in Shanghai, China. Based on a population-based prospective cohort study started from 2008 to 2012 with 15,055 Chinese female participants in Minhang district, Shanghai. Cox regression models were used to estimate the association of BMI and its interaction with a family history of cancer on breast cancer risk...
February 28, 2024: Scientific Reports
#28
JOURNAL ARTICLE
Mallory Stephenson, Henrik Ohlsson, Séverine Lannoy, Jan Sundquist, Kristina Sundquist, Alexis C Edwards
INTRODUCTION: The Interpersonal-Psychological Theory of Suicide proposes that capability for suicide is acquired through exposure to painful and provocative events (PPEs). Although there is robust evidence for a positive association between aggregate measures of PPEs and risk for suicidal behavior, little is known about the contributions of physical injuries. The present study investigated the relationship between injuries and risk of subsequent suicide attempt (SA). METHODS: Data were from Swedish population-based registers...
February 27, 2024: Acta Psychiatrica Scandinavica
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JOURNAL ARTICLE
Ming Fu, Hua Meng, Minghui Jiang, Ziwei Zhu, Xin Guan, Yansen Bai, Chenming Wang, Yuhan Zhou, Shiru Hong, Yang Xiao, Meian He, Xiaomin Zhang, Chaolong Wang, Huan Guo
The relationship of exposure to benzo [a]pyrene (BaP) with lung cancer risk has been firmly established, but whether this association could be modified by other environmental or genetic factors remains to be explored. To investigate whether and how zinc (Zn) and genetic predisposition modify the association between BaP and lung cancer, we performed a case-cohort study with a 5.4-years median follow-up duration, comprising a representative subcohort of 1399 participants and 359 incident lung cancer. The baseline concentrations of benzo [a]pyrene diol epoxide-albumin adduct (BPDE-Alb) and Zn were quantified...
February 22, 2024: Environmental Research
#30
JOURNAL ARTICLE
Luísa Santini Pinheiro, Irene Fanny Ritzel, Fernando Neves Hugo, Juliana Balbinot Hilgert, João Luiz Bastos, Roger Keller Celeste
Stress and discrimination negatively affect quality of life, but social support may buffer their effects. This study aims: (1) to examine the associations between psychological stress, discrimination, and oral health-related quality of life (OHRQoL); and (2) to assess whether social support, stress and discrimination interact to modify their associations with OHRQoL. We used cross-sectional household-based data from a study including 396 individuals aged 14 years and over from families registered for government social benefits in a city in Southern Brazil...
2024: Cadernos de Saúde Pública
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JOURNAL ARTICLE
Jinyuan Chen, Haoyu Li, Biting Zhou, Xian Li, Yihua Zhu, Yihua Yao
BACKGROUND/AIM: To investigate the independent relationships of visual impairment (VI) and Subjective cognitive complaints (SCC) with physical function impairment (PFI) and the interaction effect between VI and SCC on PFI in American older adults. METHODS: The data of this cross-sectional study was obtained from the 2005-2008 National Health and Examination Survey (NHANES) conducted in the United States. The VI criterion included both subjective self-reported eyesight conditions and objective visual acuity test results...
February 17, 2024: BMC Geriatrics
#32
JOURNAL ARTICLE
Miao Xu, Ruimei Feng, Zhonghua Liu, Xiang Zhou, Yanhong Chen, Yulu Cao, Linda Valeri, Zilin Li, Zhiwei Liu, Su-Mei Cao, Qing Liu, Shang-Hang Xie, Ellen T Chang, Wei-Hua Jia, Jincheng Shen, Youyuan Yao, Yong-Lin Cai, Yuming Zheng, Zhe Zhang, Guangwu Huang, Ingemar Ernberg, Minzhong Tang, Weimin Ye, Hans-Olov Adami, Yi-Xin Zeng, Xihong Lin
Epstein-Barr virus (EBV) and human leukocyte antigen (HLA) polymorphisms are well-known risk factors for nasopharyngeal carcinoma (NPC). However, the combined effects between HLA and EBV on the risk of NPC are unknown. We applied a causal inference framework to disentangle interaction and mediation effects between two host HLA SNPs, rs2860580 and rs2894207, and EBV variant 163364 with a population-based case-control study in NPC-endemic southern China. We discovered the strong interaction effects between the high-risk EBV subtype and both HLA SNPs on NPC risk (rs2860580, relative excess risk due to interaction [RERI] = 4...
February 14, 2024: Cell Genom
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JOURNAL ARTICLE
Amin Ziaei, Olivia Solomon, T Charles Casper, Michael Waltz, Bianca Weinstock-Guttman, Greg Aaen, Yolanda Wheeler, Jennifer Graves, Leslie Benson, Mark Gorman, Mary Rensel, Soe Mar, Tim Lotze, Benjamin Greenberg, Tanuja Chitnis, Amy T Waldman, Lauren Krupp, Judith A James, Janace Hart, Lisa F Barcellos, Emmanuelle Waubant
BACKGROUND AND OBJECTIVE: Prior Epstein-Barr virus (EBV) infection is associated with an increased risk of pediatric-onset multiple sclerosis (POMS) and adult-onset multiple sclerosis (MS). It has been challenging to elucidate the biological mechanisms underlying this association. We examined the interactions between candidate human leukocyte antigen (HLA) and non-HLA variants and childhood EBV infection as it may provide mechanistic insights into EBV-associated MS. METHODS: Cases and controls were enrolled in the Environmental and Genetic Risk Factors for Pediatric MS study of the US Network of Pediatric MS Centers...
February 9, 2024: Multiple Sclerosis: Clinical and Laboratory Research
#34
JOURNAL ARTICLE
Yuta Takemura, Koryu Sato, Richard Liang, Masanori Isobe, Naoki Kondo, Kosuke Inoue
BACKGROUND: The relationship between adverse childhood experiences (ACEs) and depression risk has been well documented. However, it remains unclear whether stress-related chronic conditions associated with ACEs, such as asthma, increase the long-term mental health burden of ACEs. OBJECTIVE: To investigate the joint association of ACEs and asthma with subsequent depressive symptoms among US adults. METHODS: This study used data from the Behavioural Risk Factor Surveillance System 2010, including 21 544 participants over 18 years old from four states where participants were questioned about ACEs...
February 2, 2024: BMJ Ment Health
#35
JOURNAL ARTICLE
Chi Zhang, Ju Cui, Shaojie Li, Ji Shen, Xuanmei Luo, Yao Yao, Hong Shi
BACKGROUND: Vitamin D deficiency and systemic inflammation share common pathological mechanisms in muscle loss, cardio-pulmonary function decline, and abnormal metabolism, which are linked to chronic conditions, senescence, and early mortality. However, their combined effect on mortality in older adults has not been well established. This study longitudinal aimed to explore the independent and combined associations of serum 25-hydroxyvitamin D [25(OH)D] and high sensitivity C-reactive protein (hs-CRP) with mortality risk in Chinese community-based older people...
February 1, 2024: BMC Geriatrics
#36
JOURNAL ARTICLE
Wenbo Jiang, Yiwei Tang, Ruiming Yang, Yujia Long, Changhao Sun, Tianshu Han, Wei Wei
BACKGROUND: This study aims to investigate potential interactions between maternal smoking around birth (MSAB) and type 2 diabetes (T2D) pathway-specific genetic risks in relation to the development of T2D in offspring. Additionally, it seeks to determine whether and how nutritional factors during different life stages may modify the association between MSAB and risk of T2D. METHODS: This study included 460,234 participants aged 40 to 69 years, who were initially free of T2D from the UK Biobank...
February 2, 2024: BMC Medicine
#37
JOURNAL ARTICLE
Wenbin Huang, Luping Luo
This study aimed to explore the influence of the interaction between vitamin D level and blood uric acid level on protein-energy wasting (PEW) in patients with Maintenance hemodialysis (MHD), in order to provide a solution for disease prevention. For this aim, a total of 150 patients with maintenance hemodialysis aged 30-79 years in a hospital were included in the study. The logistic regression model was used to analyze the relationship between vitamin D level, blood uric acid level and PEW, and the additive interaction was evaluated by calculating the relative excess risk ratio (RERI) attributive ratio (AP) and synergy index (S) of the interaction...
December 31, 2023: Cellular and Molecular Biology
#38
JOURNAL ARTICLE
Jiatao Zhang, Yu Tao, Yongchao Wang, Xiaokang Ji, Yanling Wu, Fengmei Zhang, Zhiping Wang
The combined effects of air pollution and extreme temperature on PTB remain unclear. To evaluate the independent effect and interaction effect of prenatal extreme exposure to air quality index (AQI) and Humidex, on PTB. Based on the National Health Care Data Platform of Shandong University, women who gave birth in 2019-2020 were selected for the study. First, the independent effects of AQI and Humidex on PTB were assessed by logistic regression model. Subsequently, the interaction effects of AQI and Humidex on PTB were estimated separately by calculation of the relative excess risk of interaction (RERI)...
January 19, 2024: Reproductive Toxicology
#39
JOURNAL ARTICLE
Chuanlong Cheng, Ying Liu, Chuang Han, Qidi Fang, Feng Cui, Xiujun Li
BACKGROUND: Both extreme temperature events (ETEs) and air pollution affected human health, and their effects were often not independent. Previous studies have provided limited information on the interactions between ETEs and air pollution. METHODS: We collected data on deaths (non-accidental, cardiovascular, and respiratory) in Zibo City along with daily air pollution and meteorological data from January 2015 to December 2019. Distributed lag non-linear model was used to explore the health effects of ETEs on deaths...
January 19, 2024: Science of the Total Environment
#40
JOURNAL ARTICLE
Ann Olsson, Liacine Bouaoun, Joachim Schüz, Roel Vermeulen, Thomas Behrens, Calvin Ge, Hans Kromhout, Jack Siemiatycki, Per Gustavsson, Paolo Boffetta, Benjamin Kendzia, Loredana Radoi, Christine Barul, Stefan Karrasch, Heinz-Erich Wichmann, Dario Consonni, Maria Teresa Landi, Neil E Caporaso, Franco Merletti, Enrica Migliore, Lorenzo Richiardi, Karl-Heinz Jöckel, Wolfgang Ahrens, Hermann Pohlabeln, Guillermo Fernández-Tardón, David Zaridze, John K Field, Jolanta Lissowska, Beata Świątkowska, John R McLaughlin, Paul A Demers, Miriam Schejbalova, Lenka Foretova, Vladimir Janout, Tamás Pándics, Eleonora Fabianova, Dana Mates, Francesco Forastiere, Kurt Straif, Thomas Brüning, Jelle Vlaanderen, Susan Peters
BACKGROUND: While much research has been done to identify individual workplace lung carcinogens, little is known about joint effects on risk when workers are exposed to multiple agents. OBJECTIVES: We investigated the pairwise joint effects of occupational exposures to asbestos, respirable crystalline silica, metals (i.e., nickel, chromium-VI), and polycyclic aromatic hydrocarbons (PAH) on lung cancer risk, overall and by major histologic subtype, while accounting for cigarette smoking...
January 2024: Environmental Health Perspectives
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