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https://www.readbyqxmd.com/read/28790041/impact-of-nutritional-index-on-the-association-between-phosphorus-concentrations-and-mortality-in-haemodialysis-patients-a-cohort-study-from-dialysis-outcomes-and-practice-pattern-study-in-japan
#1
Shingo Fukuma, Tatsuyoshi Ikenoue, Tadao Akizawa, Shunichi Fukuhara
OBJECTIVES: While maintenance of both phosphorus concentration and nutritional status is a major concern in managing haemodialysis patients, the interaction between these parameters is not well understood. The aim of this study was to assess whether or not nutritional index influences the association between phosphorus concentration and all-cause mortality. DESIGN: A cohort study. SETTING: The Dialysis Outcomes and Practice Pattern Study, which included 99 representative dialysis facilities in Japan between 1997 and 2010...
August 7, 2017: BMJ Open
https://www.readbyqxmd.com/read/28764134/exposure-to-polycyclic-aromatic-hydrocarbons-and-central-obesity-enhanced-risk-for-diabetes-among-individuals-with-poor-lung-function
#2
Jian Hou, Huizhen Sun, Xiji Huang, Yun Zhou, Youjian Zhang, Wenjun Yin, Tian Xu, Juan Cheng, Weihong Chen, Jing Yuan
Some studies have shown an association between obesity or exposure to polycyclic aromatic hydrocarbons (PAHs) and the risk of diabetes. This study aimed to investigate the interaction of obesity and urinary monohydroxy-PAHs (OH-PAHs) on diabetes. Individuals (n = 2716) were drawn from the baseline survey of the Wuhan-Zhuhai Cohort Study. They completed the physical examination, measurements of lung function, biochemical indices and urinary OH-PAHs levels. Additive effect of obesity and urinary ΣOH-PAHs levels on diabetes was assessed by calculating the relative excess risk due to interaction (RERI) and the attributable proportion (AP) due to interaction...
October 2017: Chemosphere
https://www.readbyqxmd.com/read/28763915/-pickled-food-fish-seafood-intakes-and-oral-squamous-cell-carcinoma-a-case-control-study
#3
J F Huang, Y Qiu, L Cai, F P Liu, F Chen, L J Yan, J F Wu, X D Bao, F Q Liu, X Y Zheng, L S Lin, B C He
Objective: To investigate the effects between fish, seafood and pickled food intakes on oral squamous cell carcinoma (OSCC). Methods: A case-control study was carried out in Fujian area during September 2010 to December 2016, in which 604 newly diagnosed primary OSCC cases confirmed by pathological diagnosis were collected from hospital and 1 343 control subjects were enrolled from community and healthy hospital population. Demographic data, history of smoking drinking and tea drinking, oral hygiene status and dietary behaviors (fish, seafood and pickled food intakes) were collected by in-person interviews using a standard questionnaire...
August 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28755257/two-way-interaction-effects-of-perioperative-complications-on-30-day-mortality-in-general-surgery
#4
Minjae Kim, Guohua Li
BACKGROUND: Multiple perioperative complications increase mortality risk, and certain complications synergistically increase this risk to a greater degree than might be expected if the complications were independent, but these effects are not well established. METHODS: This is a retrospective cohort study of 422,827 intraabdominal general surgery patients (American College of Surgeons National Surgical Quality Improvement Program 2005-2011). Eight complications were evaluated: acute respiratory failure (ARF), acute kidney injury (AKI), sepsis/septic shock, stroke, cardiac arrest (CA), myocardial infarction (MI), deep vein thrombosis/pulmonary embolus, and transfusion...
July 28, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28738465/-influencing-factors-for-non-low-response-to-hepatitis-b-vaccine-in-infants-of-hbsag-positive-mothers
#5
B Wang, X X Xu, H X Wen, H Y Hao, Z Q Yang, X H Shi, Z D Fu, X F Wang, F Zhang, B Wang, S P Wang
Objective: To investigate the influencing factors for non/low-response to hepatitis B vaccine in infants of HBsAg-positive mothers. Methods: A total of 286 HBsAg-positive pregnant women and their infants were recruited from the Third People's Hospital of Taiyuan during July 2011 to January 2013. The infants were immunized with hepatitis B vaccine according to the 0-1-6 month vaccination schedule and followed up for 12 months. The serum HBV DNA level of mothers, neonates and infants were detected by electro chemilum inescence immunoassay kits and fluorescene quantiative polymerase chain rection...
July 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28737433/association-and-interaction-between-triglyceride-glucose-index-and-obesity-on-risk-of-hypertension-in-middle-aged-and-elderly-adults
#6
Song Jian, Nie Su-Mei, Chen Xue, Zhang Jie, Wu Xue-Sen
AIMS: To investigate the association between triglyceride-glucose(TyG) index and the risk of hypertension. METHOD: A cross-sectional study was conducted in Bengbu, China. The participants received relevant questionnaire survey, anthropometric tests, and laboratory examination. Multivariate logistic regression analysis was performed to estimate the possible association between TyG index and hypertension risk. The additive interaction evaluated by the relative excess risk due to interaction (RERI), attributable proportion due to interaction (AP), and synergy index(SI) was calculated...
July 24, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28715448/effect-of-synergistic-interaction-between-abnormal-adiposity-related-metabolism-and-prediabetes-on-microalbuminuria-in-the-general-population
#7
Jong Wook Choi, Il Hwan Oh, Chang Hwa Lee, Joon-Sung Park
Central obesity and related metabolic components are important risks for microalbuminuria. To describe the effects of interactions between central obesity and related metabolic components on microalbuminuria, we conducted a nation-wide, population-based interaction analysis using cardio-metabolic index (CMI) as a candidate indicator of central obesity and related abnormal lipid metabolism. We recruited native Koreans aged 20 years or older with no medical illness. A total of 5398 participants were divided into quintiles according to CMI with sex as a covariate factor...
2017: PloS One
https://www.readbyqxmd.com/read/28653077/work-related-biomechanical-exposure-and-job-strain-in-midlife-separately-and-jointly-predict-disability-after-28-years-a-finnish-longitudinal-study
#8
K C Prakash, Subas Neupane, Päivi Leino-Arjas, Mikaela B von Bonsdorff, Taina Rantanen, Monika E von Bonsdorff, Jorma Seitsamo, Juhani Ilmarinen, Clas-Håkan Nygård
Objectives We investigated whether the extent of biomechanical exposures and job strain in midlife separately and jointly predict disability in old age. Methods Participants of the Finnish Longitudinal Study on Aging Municipal Employees (FLAME) in 1981 (aged 44-58 years) responded to disability questionnaires in 2009 (1850 women and 1082 men). Difficulties in performing five activities of daily living (ADL) and seven instrumental ADL (IADL) were used to assess severity of disability (score range: 0-12, 0=no disability)...
June 26, 2017: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/28651404/-correlation-between-insufficient-methadone-dosage-and-morphine-positive-urine-on-drop-out-of-treatment-in-patients-with-access-to-methadone-maintenance-treatment
#9
T Yao, D Feng, M H Pan, Y P Cheng, C X Li, J Wang, Y L Feng, J Shi, T Su, Q Chen, S Shi, S P Wang
Objective: To estimate the incidence of drop out of treatment in patients with access to methadone maintenance treatment and explore the correlation and interaction between insufficient methadone dosage and morphine positive urine on the drop out in Guangxi Zhuang Autonomous Region. Methods: Face to face interview was conducted in 1 031 patients at 3 methadone maintenance treatment clinics in Guangxi. Results: The study included 1 031 participants, 40.6% of them (419/1 031) had stopped treatment. The drop out rates in urine morphine positive group and methadone dosage<100 mg/d group were 57...
May 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28584635/interactions-between-polymorphisms-in-the-3-untranslated-region-of-the-cyclin-dependent-kinase-6-gene-and-the-human-papillomavirus-infection-and-risk-of-cervical-precancerous-lesions
#10
Xingguang Ye, Lipeng Jing, Xingming Zhong, Di Xiao, Meiling Ou, Congcong Guo, Guang Yang, Chunxia Jing, Xiangcai Wei
The human papillomavirus (HPV) infection is essential for the development of cervical cancer and its precursor lesions. However, only certain persistently infected individuals develop cervical cancer. Cyclin-dependent kinase 6 (CDK6) is a critical regulatory cancer-associated gene in the cell cycle and in tumorigenesis. Single nucleotide polymorphisms (SNPs) in microRNA sites in the 3'-untranslated region (UTR) of target genes may result in target gene expression level changes and susceptibility to diseases, including cancer...
June 2017: Biomedical Reports
https://www.readbyqxmd.com/read/28553992/does-age-modify-the-association-between-psychosocial-factors-at-work-and-deterioration-of-self-rated-health
#11
Hermann Burr, Hans Martin Hasselhorn, Norbert Kersten, Anne Pohrt, Reiner Rugulies
Objectives Few epidemiological studies have examined whether associations of psychosocial working conditions with risk of poor health differ by age. Based on results from mostly cross-sectional studies, we test whether (i) psychosocial relational factors (social support) are more strongly associated with declining health of older than younger employees and (ii) psychosocial job factors (workpace, influence, possibilities for development) are more strongly associated with declining health of younger than older employees...
May 29, 2017: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/28516333/risk-of-hip-fracture-in-older-people-using-selective-serotonin-reuptake-inhibitors-and-other-psychoactive-medicines-concurrently-a-matched-case-control-study-in-australia
#12
Michael J Leach, Nicole L Pratt, Elizabeth E Roughead
BACKGROUND: Few studies have assessed the risk of hip fracture following concurrent use of psychoactive medicines, and none has investigated combinations with selective serotonin reuptake inhibitors. OBJECTIVES: To assess the risk of hip fracture in older people as a result of concurrent use of selective serotonin reuptake inhibitors and other psychoactive medicines. METHODS: A matched case-control design was employed. Cases were Australian Government Department of Veterans' Affairs beneficiaries aged over 65 years who experienced a hip fracture between 2009 and 2012...
June 2017: Drugs—Real World Outcomes
https://www.readbyqxmd.com/read/28486582/binge-drinking-modifies-the-association-between-lifetime-alcohol-intake-and-breast-cancer-risk-in-moderate-drinkers
#13
Alexandra J White, Lisa A DeRoo, Clarice R Weinberg, Dale P Sandler
The prevalence of binge drinking is rising in the United States. While alcohol is a breast cancer risk factor, less is known about the impact of episodic heavy drinking. Breast cancer-free women, ages 35-74, were enrolled in the Sister Study from 2003-2009 (n = 50,884). United States or Puerto Rico residents who had a sister with breast cancer were eligible. Multivariable Cox regression was used to estimate adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for breast cancer. 1,843 invasive breast cancers were diagnosed during follow-up (mean = 6...
May 9, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28421238/the-impact-of-low-education-and-poor-health-on-unemployment-varies-by-work-life-stage
#14
Sander K R van Zon, Sijmen A Reijneveld, Carlos F Mendes de Leon, Ute Bültmann
OBJECTIVES: The aim of this study is to examine associations and interactions of education, and physical and mental health with unemployment in early, mid, and late work life. METHODS: This cross-sectional study uses data from 69,118 respondents from Lifelines. Health status was measured with the RAND-36, education was self-reported, and participants working <12 h per week or indicating to be unemployed were considered unemployed. The relative excess risk due to interaction (RERI) was calculated to measure interaction on the additive scale...
April 18, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/28391246/influence-of-obesity-and-physical-workload-on-disability-benefits-among-construction-workers-followed-up-for-37-years
#15
Suzan J W Robroek, Bengt Järvholm, Allard J van der Beek, Karin I Proper, Jens Wahlström, Alex Burdorf
OBJECTIVES: The objectives of this study are to investigate the relation between obesity and labour force exit via diagnosis-specific disability benefits, and whether physical workload modifies this association. METHODS: A longitudinal analysis was performed among 3 28 743 Swedish construction workers in the age of 15-65 years. Body weight and height were measured at a health examination and enriched with register information on disability benefits up to 37 years later...
April 8, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28389496/the-interaction-of-socioeconomic-position-and-type-2-diabetes-mellitus-family-history-a-cross-sectional-analysis-of-the-lifelines-cohort-and-biobank-study
#16
Sander K R van Zon, Harold Snieder, Ute Bültmann, Sijmen A Reijneveld
BACKGROUND: Low socioeconomic position (SEP) and family history of type 2 diabetes mellitus (T2DM) contribute to increased T2DM risk, but it is unclear whether they exacerbate each other's effect. This study examined whether SEP reinforces the association of T2DM family history with T2DM, and whether behavioural and clinical risk factors can explain this reinforcement. METHODS: We used cross-sectional data on 51 725 participants from Lifelines. SEP was measured as educational level and was self-reported, just as family history of T2DM...
April 7, 2017: BMJ Open
https://www.readbyqxmd.com/read/28381121/the-association-of-health-and-voluntary-early-retirement-pension-and-the-modifying-effect-of-quality-of-supervision-results-from-a-danish-register-based-follow-up-study
#17
Astrid de Wind, Hermann Burr, Anne Pohrt, Hans Martin Hasselhorn, Allard Johan Van der Beek, Reiner Rugulies
OBJECTIVES: The aims of this article are to (1) determine whether and to what extent general perceived health and quality of supervision predict voluntary early retirement pension (VERP) and (2) assess whether quality of supervision modifies the association between general perceived health and VERP. METHODS: Employees aged 49-64 years who participated in the Danish Work Environment Cohort Study in 2000 were selected. Their questionnaire data about health and work were linked to register data on social transfer payments, among others VERP, from 2001 to 2012 in the Danish Register for Evaluation of Marginalization ( N=1167)...
July 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28328829/combined-effect-of-obesity-and-uric-acid-on-nonalcoholic-fatty-liver-disease-and-hypertriglyceridemia
#18
Shujun Zhang, Tingting Du, Mengni Li, Huiming Lu, Xuan Lin, Xuefeng Yu
Hyperuricemia is associated with metabolic syndrome (MetS), but the association is often confounded by the shared background of obesity. We sought to explore the modifying effects of obesity on the association between uric acid (UA), MetS components, and nonalcoholic fatty liver disease (NAFLD).We conducted a cross-sectional study in a Chinese population of 10,069 participants aged ≥20 years. Multiplicative interaction between obesity (BMI ≥25 kg/m) and elevated UA was assessed using an interaction term in a logistic regression analysis...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28324062/gene-hormone-therapy-interaction-and-fracture-risk-in-postmenopausal-women
#19
Youjin Wang, Jean Wactawski-Wende, Lara E Sucheston-Campbell, Leah Preus, Kathleen M Hovey, Jing Nie, Rebecca D Jackson, Samuel K Handelman, Rami Nassir, Carolyn J Crandall, Heather M Ochs-Balcom
Context: Evidence supports a protective effect of menopausal hormone therapy (HT) on bone. However, whether genetic susceptibility modifies the association of HT and fracture risk is not sufficiently explored. Objective: The objective was to test an interaction between genetic susceptibility and HT on fracture risk. Design: We constructed two weighted genetic risk scores (GRSs) based on 16 fracture-associated variants (Fx-GRSs) and 50 bone mineral density variants (BMD-GRSs)...
June 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28251240/does-age-modify-the-association-between-physical-work-demands-and-deterioration-of-self-rated-general-health
#20
Hermann Burr, Anne Pohrt, Reiner Rugulies, Andreas Holtermann, Hans Martin Hasselhorn
Objective Due to the growing proportion of older employees in the work force in several countries, the importance of age in the association between work and health is becoming increasingly relevant. Few studies have investigated whether age modifies the association of physical work demands with health. We hypothesized that the association of demanding body postures with deteriorated self-rated health (SRH) is stronger among older employees than among younger employees. Method We analyzed three 5-year cohorts in the Danish Work Environment Cohort Study comprising 8318 observations from 5204 employees (follow-up participation rate 83%) with good baseline SRH...
May 1, 2017: Scandinavian Journal of Work, Environment & Health
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