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https://www.readbyqxmd.com/read/28437779/further-evidence-of-male-offspring-preference-for-certain-subgroups-in-the-united-states-2007-2015
#1
Grech Victor
INTRODUCTION: Males are born in excess of females. This ratio (M/T=male/total births) is influenced by various factors. A recent study showed that M/T in the United States (US) is Asian or Pacific Islander>White>American Indian or Alaska Native>Black or African American. This study was carried out in order to ascertain whether there are M/T differences in different races in the US by birth order. METHODS: Monthly male and female live births by race and birth order for the entire US were obtained for 2007-2015 with birth order as 1-≥6 for these races...
April 21, 2017: Early Human Development
https://www.readbyqxmd.com/read/28437694/the-benefits-of-paid-maternity-leave-for-mothers-post-partum-health-and-wellbeing-evidence-from-an-australian-evaluation
#2
Belinda Hewitt, Lyndall Strazdins, Bill Martin
This paper investigates the health effects of the introduction of a near universal paid parental leave (PPL) scheme in Australia, representing a natural social policy experiment. Along with gender equity and workforce engagement, a goal of the scheme (18 weeks leave at the minimum wage rate) was to enhance the health and wellbeing of mothers and babies. Although there is evidence that leave, especially paid leave, can benefit mothers' health post-partum, the potential health benefits of implementing a nationwide scheme have rarely been investigated...
April 14, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28437659/the-relationship-between-maternal-education-and-the-neural-substrates-of-phoneme-perception-in-children-interactions-between-socioeconomic-status-and-proficiency-level
#3
Lisa L Conant, Einat Liebenthal, Anjali Desai, Jeffrey R Binder
Relationships between maternal education (ME) and both behavioral performances and brain activation during the discrimination of phonemic and nonphonemic sounds were examined using fMRI in children with different levels of phoneme categorization proficiency (CP). Significant relationships were found between ME and intellectual functioning and vocabulary, with a trend for phonological awareness. A significant interaction between CP and ME was seen for nonverbal reasoning abilities. In addition, fMRI analyses revealed a significant interaction between CP and ME for phonemic discrimination in left prefrontal cortex...
April 21, 2017: Brain and Language
https://www.readbyqxmd.com/read/28437305/breast-feeding-analgesia-in-infants-an-update-on-the-current-state-of-evidence
#4
Britney Benoit, Ruth Martin-Misener, Margot Latimer, Marsha Campbell-Yeo
To provide an updated synthesis of the current state of the evidence for the effectiveness of breast-feeding and expressed breast milk feeding in reducing procedural pain in preterm and full-term born infants. A systematic search of key electronic databases (PubMed, CINAHL, EMBASE) was completed. Of the 1032 abstracts screened, 21 were found eligible for inclusion. Fifteen studies reported on the use of breast-feeding or expressed breast milk in full-term infants and 6 reported on preterm infants. Direct breast-feeding was more effective than maternal holding, maternal skin-to-skin contact, topical anesthetics, and music therapy, and was as or more effective than sweet tasting solutions in full-term infants...
April 2017: Journal of Perinatal & Neonatal Nursing
https://www.readbyqxmd.com/read/28436452/disrupted-neuronal-maturation-in-angelman-syndrome-derived-induced-pluripotent-stem-cells
#5
James J Fink, Tiwanna M Robinson, Noelle D Germain, Carissa L Sirois, Kaitlyn A Bolduc, Amanda J Ward, Frank Rigo, Stormy J Chamberlain, Eric S Levine
Angelman syndrome (AS) is a neurogenetic disorder caused by deletion of the maternally inherited UBE3A allele and is characterized by developmental delay, intellectual disability, ataxia, seizures and a happy affect. Here, we explored the underlying pathophysiology using induced pluripotent stem cell-derived neurons from AS patients and unaffected controls. AS-derived neurons showed impaired maturation of resting membrane potential and action potential firing, decreased synaptic activity and reduced synaptic plasticity...
April 24, 2017: Nature Communications
https://www.readbyqxmd.com/read/28436446/opioid-self-administration-is-attenuated-by-early-life-experience-and-gene-therapy-for-anti-inflammatory-il-10-in-the-nucleus-accumbens-of-male-rats
#6
Michael J Lacagnina, Ashley M Kopec, Stewart S Cox, Richa Hanamsagar, Corinne Wells, Susan Slade, Peter M Grace, Linda R Watkins, Edward D Levin, Staci D Bilbo
Early-life conditions can contribute to the propensity for developing neuropsychiatric disease, including substance abuse disorders. However, the long-lasting mechanisms that shape risk or resilience for drug addiction remain unclear. Previous work has shown that a neonatal handling procedure in rats (which promotes enriched maternal care) attenuates morphine conditioning, reduces morphine-induced glial activation, and increases microglial expression of the anti-inflammatory cytokine interleukin-10 (IL-10)...
April 24, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28436235/the-effect-of-epidural-analgesia-alone-and-in-association-with-other-variables-on-the-risk-of-cesarean-section
#7
Antonio Herrera-Gómez, Elvira De Luna-Bertos, Javier Ramos-Torrecillas, Francisco Manuel Ocaña-Peinado, Olga García-Martínez, Concepción Ruiz
INTRODUCTION: Epidural analgesia (EA) is the most widespread pharmacologic method of labor pain relief. There remains disagreement, however, regarding its adverse effects. The objective of this study was to determine the effect of EA administration on the risk of cesarean delivery and its causes (e.g., stalled labor, risk of loss of fetal well-being, among others) and the degree to which this effect may be modulated by mother-, newborn-, and labor-related variables. METHOD: A retrospective cohort observational study was conducted including all deliveries in a Spanish public hospital between March 2010 and March 2013 ( N = 2,450; EA = 562, non-EA = 1,888)...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28436175/chronic-hypertension-and-adverse-pregnancy-outcomes-a-cohort-study
#8
Anca M Panaitescu, Argyro Syngelaki, Natalia Prodan, Ranjit Akolekar, Kypros H Nicolaides
OBJECTIVE: To examine the association between chronic hypertension (CH) and a wide range of adverse pregnancy outcomes after adjustment for confounding factors in obstetric history and maternal characteristics. METHODS: This was a prospective screening study for adverse pregnancy outcomes in women with singleton pregnancies attending the first routine hospital visit at 11(+0) -13(+6) weeks' gestation. Data on maternal characteristics, medical and obstetric history and pregnancy outcomes were collected...
April 23, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28436119/maternal-hypertrophy-and-diastolic-disfunction-and-brain-natriuretic-peptide-concentration-in-early-and-late-pre-eclampsia
#9
V T M Borges, S G Zanati, M T S PeraÇoli, J R Poiati, M Romão-Veiga, J C PeraÇoli, B Thilaganathan
OBJECTIVE: Pre-eclampsia is associated with maternal cardiac remodelling and diastolic dysfunction. The aim of this study was to assess and compare maternal left ventricular structure and diastolic function and Brain Natriuretic Peptide (BNP) levels in women with early-onset pre-eclampsia (<34 weeks of gestation) and late-onset pre-eclampsia (≥34weeks of gestation). METHODS: A prospective, cross-sectional observational study was performed in 30 women with early-onset pre-eclampsia, 32 with late-onset pre-eclampsia and 23 normotensive controls...
April 23, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28435983/-effect-of-high-altitude-hypoxia-on-fetal-development-during-pregnancy-and-the-reason-analysis
#10
Juan-Li Liu, Si-Qing Ma, Ta-Na Wuren
High altitude hypoxia is an important factor to affect fetal development during pregnancy. In the special environment, maternal physiological functions are regulated to maintain the maternal and fetal homeostasis, so that limited oxygen is to meet the needs of fetal growth and development. In this review, the literatures about the effects of hypoxic environment on fetal development during pregnancy in recent years were summarized, in which the fetal growth characteristics, maternal physiological regulation, genetic and placental influencing factors in high altitude areas were involved...
April 25, 2017: Sheng Li Xue Bao: [Acta Physiologica Sinica]
https://www.readbyqxmd.com/read/28435650/postnatal-transitional-weight-loss-and-adverse-outcomes-in-extremely-premature-neonates
#11
Rita P Verma, Syed Shibli, Eugene Komaroff
The early postnatal weight loss (EPWL) is highly variable in the extremely low birth weight infants (birth weight <1000 g, ELBW). It is reported to be unassociated with adverse outcomes within a range of 3-21% of birth weight. Its wide range might have contributed to this lack of association. The aim of our paper is to study the effects of maximum EPWL, graded as low, medium and large on clinical outcomes in ELBW infants. In a retrospective cohort observational study EPWL was measured as maximum weight loss from birth weight (MWL) in ELBW infants and grouped as low (5-12%) moderate (18...
March 22, 2017: Pediatric Reports
https://www.readbyqxmd.com/read/28435022/maternal-separation-induced-hippocampal-changes-in-cadherin-1-cdh-1-mrna-and-on-recognition-memory-in-adolescent-mice
#12
Lucas Araújo de Azeredo, Luis Eduardo Wearick-Silva, Thiago Wendt Viola, Saulo Gantes Tractenberg, Anderson Centeno da Silva, Rodrigo Orso, Nadja Schröder, Timothy William Bredy, Rodrigo Grassi-Oliveira
In rodents, disruption of mother-infant attachment induced by maternal separation (MS) is associated with recognition memory impairment and long-term neurobiological consequences. Particularly stress-induced modifications have been associated to disruption of cadherin (CDH) adhesion function, which plays an important role in remodeling of neuronal connection and synaptic plasticity. This study investigated the sex-dependent effect of MS on recognition memory and mRNA levels of classical type I and type II CDH and the related β -catenin (β -Cat) in the hippocampus and prefrontal cortex of late adolescent mice...
April 20, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28434870/maternal-socioeconomic-disadvantage-is-associated-with-transcriptional-indications-of-greater-immune-activation-and-slower-tissue-maturation-in-placental-biopsies-and-newborn-cord-blood
#13
Gregory E Miller, Ann E Borders, Amy H Crockett, Kharah M Ross, Sameen Qadir, Lauren Keenan-Devlin, Adam K Leigh, Paula Ham, Jeffrey Ma, Jesusa M G Arevalo, Linda M Ernst, Steve W Cole
Children from economically disadvantaged families experience worse cognitive, psychiatric, and medical outcomes compared to more affluent youth. Preclinical models suggest some of the adverse influence of disadvantage could be transmitted during gestation via maternal immune activation, but this hypothesis has not been tested in humans. It also remains unclear whether prenatal interventions can mitigate such effects. To fill these gaps, we conducted two studies. Study 1 characterized the socioeconomic conditions of 79 women during pregnancy...
April 20, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28434107/early-life-obesity-prevention-critique-of-intervention-trials-during-the-first-one-thousand-days
#14
REVIEW
John J Reilly, Anne Martin, Adrienne R Hughes
PURPOSE OF REVIEW: To critique the evidence from recent and ongoing obesity prevention interventions in the first 1000 days in order to identify evidence gaps and weaknesses, and to make suggestions for more informative future intervention trials. RECENT FINDINGS: Completed and ongoing intervention trials have had fairly modest effects, have been limited largely to high-income countries, and have used relatively short-term interventions and outcomes. Comparison of the evidence from completed prevention trials with the evidence from systematic reviews of behavioral risk factors shows that some life-course stages have been neglected (pre-conception and toddlerhood), and that interventions have neglected to target some important behavioral risk factors (maternal smoking during pregnancy, infant and child sleep)...
April 22, 2017: Current Obesity Reports
https://www.readbyqxmd.com/read/28434056/beyond-the-primary-endpoint-paradigm-a-test-of-intervention-effect-in-hiv-behavioral-intervention-trials-with-numerous-correlated-outcomes
#15
Jessica M Harwood, Robert E Weiss, W Scott Comulada
Behavioral interventions are increasingly based on holistic approaches to health with an understanding that health-related behaviors are linked. A motivating example is provided by the Philani study, an intervention trial conducted to improve the health of South African mothers and their children. Inter-related health problems around maternal alcohol use, malnutrition, and HIV were addressed; multiple endpoints were targeted. The traditional hypothesis testing paradigm that tests significance on one primary outcome did not suffice...
April 22, 2017: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/28433802/role-of-environmental-stressors-in-determining-the-developmental-outcome-of-neonatal-anesthesia
#16
Ling-Sha Ju, Jiao-Jiao Yang, Nikolaus Gravenstein, Christoph N Seubert, Timothy E Morey, Colin Sumners, Terrie Vasilopoulos, Jian-Jun Yang, Anatoly E Martynyuk
BACKGROUND: The majority of studies evaluating neurocognition in humans who had procedures under anesthesia early in life found long-term deficits even though the typical anesthesia duration normalized to the human life span is much shorter than that shown to induce developmental abnormalities in rodents. Therefore, we studied whether subsequent environmental stressors contribute to deficiencies programmed by a brief neonatal etomidate exposure. METHODS: Postnatal days (P) 4, 5, or 6, Sprague-Dawley rats, pretreated with vehicle or the Na(+)-K(+)-2Cl(-) (NKCC1) inhibitor, bumetanide, received two injections of etomidate resulting in anesthesia for 2h...
April 7, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28433797/development-of-comorbid-crying-sleeping-feeding-problems-across-infancy-neurodevelopmental-vulnerability-and-parenting
#17
Ayten Bilgin, Dieter Wolke
BACKGROUND: Regulatory problems (excessive crying, feeding, and sleeping difficulties), specifically their comorbidity, are early warning signs of future problems. Insensitive parenting and neurodevelopmental vulnerabilities have been suggested as factors explaining development or maintenance of regulatory problems. Nevertheless, none of the previous studies investigated these factors within the same sample across infancy, taking into account the reciprocal influences between maternal sensitivity and regulatory problems...
April 19, 2017: Early Human Development
https://www.readbyqxmd.com/read/28433734/prospective-association-of-fetal-liver-blood-flow-at-30-weeks-gestation-with-newborn-adiposity
#18
Satoru Ikenoue, Feizal Waffarn, Masanao Ohashi, Kaeko Sumiyoshi, Chigusa Ikenoue, Claudia Buss, Daniel L Gillen, Hyagriv N Simhan, Sonja Entringer, Pathik D Wadhwa
BACKGROUND: The production of variation in adipose tissue accretion represents a key fetal adaptation to energy substrate availability during gestation. Because umbilical venous blood transports nutrient substrate from the maternal to the fetal compartment, and the fetal liver is the primary organ where nutrient inter-conversion occurs, it has been proposed that variations in the relative distribution of umbilical venous blood flow shunting either through ductus venosus or perfusing the fetal liver represents a mechanism underlying this adaptation...
April 19, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28433704/pertussis-and-influenza-immunisation-during-pregnancy-a-landscape-review
#19
REVIEW
Bahaa Abu Raya, Kathryn M Edwards, David W Scheifele, Scott A Halperin
Immunisation during pregnancy is a relatively new strategy, and is currently limited to tetanus, pertussis, and influenza vaccines. None of these vaccines were developed specifically for use in pregnancy, but they provide an effective method of protecting mothers and young infants. In response to increases in pertussis morbidity and mortality among young infants, several countries have recommended universal tetanus, diphtheria, and acellular pertussis immunisation during pregnancy. Similarly, many countries recommend influenza immunisation during pregnancy to reduce the risk of disease for mother and infant...
April 19, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28433624/temporal-slice-registration-and-robust-diffusion-tensor-reconstruction-for-improved-fetal-brain-structural-connectivity-analysis
#20
Bahram Marami, Seyed Sadegh Mohseni Salehi, Onur Afacan, Benoit Scherrer, Caitlin K Rollins, Edward Yang, Judy A Estroff, Simon K Warfield, Ali Gholipour
Diffusion weighted magnetic resonance imaging, or DWI, is one of the most promising tools for the analysis of neural microstructure and the structural connectome of the human brain. The application of DWI to map early development of the human connectome in-utero, however, is challenged by intermittent fetal and maternal motion that disrupts the spatial correspondence of data acquired in the relatively long DWI acquisitions. Fetuses move continuously during DWI scans. Reliable and accurate analysis of the fetal brain structural connectome requires careful compensation of motion effects and robust reconstruction to avoid introducing bias based on the degree of fetal motion...
April 19, 2017: NeuroImage
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