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Probiotic AND METABOLISM

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https://www.readbyqxmd.com/read/29121515/the-genetic-basis-underlying-variation-in-production-of-the-flavour-compound-diacetyl-by-lactobacillus-rhamnosus-strains-in-milk
#1
Raquel Lo, Van Thi Thuy Ho, Nidhi Bansal, Mark S Turner
Diacetyl and the closely related compound acetoin impart desirable buttery flavour and odour to many foods including cheese and are generated through the metabolism of citrate by lactic acid bacteria (LAB). To increase the levels of these compounds, adjunct cultures capable of producing them can be added to cheese fermentations. In this study, we compared the diacetyl and acetoin producing abilities of 13 Lactobacillus rhamnosus strains from cheese sources. Diacetyl and acetoin production was found to be a common feature of Lb...
October 31, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29119101/effect-of-dual-infection-with-eimeria-tenella-and-subgroup-j-avian-leukosis-virus-on-the-cecal-microbiome-in-specific-pathogen-free-chicks
#2
Ning Cui, Xiuzhen Wang, Qi Wang, Hongmei Li, Fangkun Wang, Xiaomin Zhao
Understanding gut microflora alterations associated with gut parasites and other pathogens that drive these alterations may help to promote the understanding of intestinal flora's role in multiple-infected individuals. This study examined the effects of dual infection with Eimeria tenella and subgroup J avian leukosis virus (ALV-J) on the chick cecal microbiome. Specific-pathogen-free (SPF) chicks were infected with either ALV-J strain NX0101 at 1 day of age or E. tenella at 14 days of age, another group was infected with both pathogens...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29114245/the-selective-interaction-of-pistacia-lentiscus-oil-vs-human-streptococci-an-old-functional-food-revisited-with-new-tools
#3
Germano Orrù, Cristina Demontis, Antonello Mameli, Enrica Tuveri, Pierpaolo Coni, Giuseppina Pichiri, Ferdinando Coghe, Antonella Rosa, Paola Rossi, Guy D'hallewin
Pistacia lentiscus berry oil (LBO) represents a typical vegetal product of the Mediterranean basin that has been formally used in traditional cuisine for 100s of years. In addition to its interesting alimentary properties, this product could represent an interesting candidate in the field of research on the study of new anti-infective agents. In fact, in Mediterranean countries, lentisk oil still continues to be widely used in folk medicine for oral and skin affections, in particular, acute gingivitis, pediatric skin infections such as impetigo and foot plaques, and biofilm related infections often associated with Streptococcus spp...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29113509/the-microbial-metabolite-indole-3-propionic-acid-improves-glucose-metabolism-in-rats-but-does-not-affect-behaviour
#4
Anders Abildgaard, Betina Elfving, Marianne Hokland, Gregers Wegener, Sten Lund
CONTEXT: We have previously shown that an antidepressant-like effect of probiotics in rats was associated with a higher plasma level of the microbial tryptophan metabolite indole-3-propionic acid (IPA). OBJECTIVE: We therefore wanted to study the isolated effect of IPA on behaviour and glucose metabolism in rats. METHODS: Male Sprague-Dawley rats were fed control or IPA-enriched diet for six weeks (n = 12 per group) and assessed in the elevated plus maze, open field and forced swim test...
November 7, 2017: Archives of Physiology and Biochemistry
https://www.readbyqxmd.com/read/29109959/probiotic-bacteria-for-healthier-aging-immunomodulation-and-metabolism-of-phytoestrogens
#5
REVIEW
José María Landete, Pilar Gaya, Eva Rodríguez, Susana Langa, Ángela Peirotén, Margarita Medina, Juan L Arqués
Age-related degeneration gives rise to a number of pathologies, many of them associated with imbalances of the microbiota and the gut-associated immune system. Thus, the intestine is considered a key target organ to improve the quality of life in senescence. Gut microbiota can have a powerful impact in the deterioration linked to aging by its nutritional and immunomodulatory activity. Reduced numbers of beneficial species and low microbial biodiversity in the elderly have been linked with pathogenesis of many diseases...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29107841/a-novel-non-dairy-beverage-from-durian-pulp-fermented-with-selected-probiotics-and-yeast
#6
Yuyun Lu, Satya Dwi Putra, Shao-Quan Liu
This study investigated the effects of sequential inoculation (Seq-I) of Bifidobacterium animalis subsp. lactis or Lactobacillus casei with yeast Williopsis saturnus on durian pulp fermentation. Seq-I of W. saturnus following B. animalis subsp. lactis did not bring about any significant differences compared to the B. animalis subsp. lactis monoculture due to the sharp early death of W. saturnus soon after inoculation. However, Seq-I of W. saturnus significantly enhanced the survival of L. casei and improved the utilization of fructose and glucose compared to L...
October 31, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29101668/gut-microbiota-are-disease-modifying-factors-after-traumatic-spinal-cord-injury
#7
REVIEW
Kristina A Kigerl, Klauss Mostacada, Phillip G Popovich
Spinal cord injury (SCI) disrupts the autonomic nervous system (ANS), impairing its ability to coordinate organ function throughout the body. Emerging data indicate that the systemic pathology that manifests from ANS dysfunction exacerbates intraspinal pathology and neurological impairment. Precisely how this happens is unknown, although new data, in both humans and in rodent models, implicate changes in the composition of bacteria in the gut (i.e., the gut microbiota) as disease-modifying factors that are capable of affecting systemic physiology and pathophysiology...
November 3, 2017: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://www.readbyqxmd.com/read/29097999/clostridium-butyricum-cgmcc0313-1-protects-against-autoimmune-diabetes-by-modulating-intestinal-immune-homeostasis-and-inducing-pancreatic-regulatory-t-cells
#8
Lingling Jia, Kai Shan, Li-Long Pan, Ninghan Feng, Zhuwu Lv, Yajun Sun, Jiahong Li, Chengfei Wu, Hao Zhang, Wei Chen, Julien Diana, Jia Sun, Yong Q Chen
Recent evidence indicates that indigenous Clostridium species induce colonic regulatory T cells (Tregs), and gut lymphocytes are able to migrate to pancreatic islets in an inflammatory environment. Thus, we speculate that supplementation with the well-characterized probiotics Clostridium butyricum CGMCC0313.1 (CB0313.1) may induce pancreatic Tregs and consequently inhibit the diabetes incidence in non-obese diabetic (NOD) mice. CB0313.1 was administered daily to female NOD mice from 3 to 45 weeks of age. The control group received an equal volume of sterile water...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29094115/lactobacillus-plantarum-hnu082-derived-improvements-in-the-intestinal-microbiome-prevent-the-development-of-hyperlipidaemia
#9
Yuyu Shao, Dongxue Huo, Qiannan Peng, Yuyang Pan, Shuaiming Jiang, Bin Liu, Jiachao Zhang
Restricted by research techniques, the probiotic-derived changes in the microbiome and microbial metabolites correlated with the potential prevention of hyperlipidaemia have remained undiscovered. In the present research, a metagenomic approach was applied to describe Lactobacillus plantarum HNU082 consumption-derived changes in the intestinal microbiome and their correlation with the occurrence and development of hyperlipidaemia. Principal coordinate analysis based on UniFrac distances indicated that the intestinal microbiota was profoundly altered in the hyperlipidaemia group, and probiotic consumption regulated the bias in the intestinal microbial structure in hyperlipidaemia...
November 2, 2017: Food & Function
https://www.readbyqxmd.com/read/29090088/gut-microbiota-as-a-potential-target-of-metabolic-syndrome-the-role-of-probiotics-and-prebiotics
#10
REVIEW
Mingqian He, Bingyin Shi
Metabolic syndrome (MS) comprises central obesity, increased plasma glucose levels, hyperlipidemia and hypertension, and its incidence is increasing due to changes in lifestyle and dietary structure in recent years. MS has been proven to be associated with an increased incidence of cardiovascular diseases and type 2 diabetes mellitus, leading to morbidity and mortality. In this manuscript, we review recent studies concerning the role of the gut microbiota in MS modulation. Manipulation of the gut microbiota through the administration of prebiotics or probiotics may assist in weight loss and reduce plasma glucose and serum lipid levels, decreasing the incidence of cardiovascular diseases and type 2 diabetes mellitus...
2017: Cell & Bioscience
https://www.readbyqxmd.com/read/29083037/review-article-the-gut-microbiome-as-a-therapeutic-target-in-the-pathogenesis-and-treatment-of-chronic-liver-disease
#11
REVIEW
C A Woodhouse, V C Patel, A Singanayagam, D L Shawcross
BACKGROUND: Mortality from chronic liver disease is rising exponentially. The liver is intimately linked to the gut via the portal vein, and exposure to gut microbiota and their metabolites translocating across the gut lumen may impact upon both the healthy and diseased liver. Modulation of gut microbiota could prove to be a potential therapeutic target. AIM: To characterise the changes in the gut microbiome that occur in chronic liver disease and to assess the impact of manipulation of the microbiome on the liver...
October 30, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29079994/osteomicrobiology-a-new-cross-disciplinary-research-field
#12
REVIEW
Claes Ohlsson, Klara Sjögren
The mutualistic interaction between the gut microbiota (GM) and its host profoundly shapes many aspects of our physiology. The composition and activity of the gut microbiota is modulated by environmental factors such as dietary habits and antibiotic treatments. In rodents, studies demonstrate that the GM is a crucial regulator of bone metabolism and that modulation of the GM composition by probiotic interventions can prevent castration-induced bone loss. Short-term colonization of germ-free mice with GM results in an activation of CD4+T cells, resulting in increased levels of pro-inflammatory cytokines in bone and thereby activation of osteoclastic bone resorption...
October 27, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/29079990/the-effects-of-synbiotic-supplementation-on-carotid-intima-media-thickness-biomarkers-of-inflammation-and-oxidative-stress-in-people-with-overweight-diabetes-and-coronary-heart-disease-a-randomized-double-blind-placebo-controlled-trial
#13
Alireza Farrokhian, Fariba Raygan, Ali Soltani, Maryam Tajabadi-Ebrahimi, Mehran Sharifi Esfahani, Ali Akbar Karami, Zatollah Asemi
Synbiotics are known to exert multiple beneficial effects, including anti-inflammatory and antioxidant actions. The aim of this study was to evaluate the effects of synbiotic supplementation on carotid intima-media thickness (CIMT), biomarkers of inflammation, and oxidative stress in people with overweight, diabetes, and coronary heart disease (CHD). This randomized, double-blind, placebo-controlled trial was conducted and involved 60 people with overweight, diabetes, and CHD, aged 50-85 years old. Participants were randomly allocated into two groups to take either synbiotic supplements containing three probiotic bacteria spices Lactobacillus acidophilus strain T16 (IBRC-M10785), Lactobacillus casei strain T2 (IBRC-M10783), and Bifidobacterium bifidum strain T1 (IBRC-M10771) (2 × 10(9) CFU/g each) plus 800 mg inulin or placebo (n = 30 each group) for 12 weeks...
October 27, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29073182/blood-parameters-as-biomarkers-in-a-salmonella-spp-disease-model-of-weaning-piglets
#14
Emili Barba-Vidal, Victor Fernando Buttow Roll, Edgar Garcia Manzanilla, Carlos Torrente, José Antonio Moreno Muñoz, José Francisco Pérez, Susana María Martín-Orúe
BACKGROUND: The weaning pig is used as an experimental model to assess the impact of diet on intestinal health. Blood parameters (BP) are considered a useful tool in humans, but there is very scarce information of such indicators in the weaning pig. The objective of the present study is to evaluate the use of different BP as indicators in an experimental model of salmonellosis. METHODOLOGY: Seventy-two 28-day-old piglets were divided into four groups in a 2x2 factorial arrangement, with animals receiving or not a probiotic combination based on B...
2017: PloS One
https://www.readbyqxmd.com/read/29072432/effectiveness-of-7-day-and-14-day-moxifloxacin-dexlansoprazole-based-triple-therapy-and-probiotic-supplement-for-helicobacter-pylori-eradication-in-thai-patients-with-non-ulcer-dyspepsia-a-double-blind-randomized-placebo-controlled-study
#15
Peranart Chotivitayatarakorn, Varocha Mahachai, Ratha-Korn Vilaichone
Background: Helicobacter pylori (H. pylori) is important cause of peptic ulcer and gastric cancer. Moxifloxacin is effective antibiotic for treatment for H. pylori. However, there were limited studies as first line therapy. Probiotics had been shown to decrease therapy-related side-effect and increase eradication rate. Aim of this study was to evaluate the efficacy of moxifloxacin-dexlansoprazole based triple therapy with probiotic for H. pylori treatment in Thailand. Methods: Patients with H. pylori infected gastritis were randomized to receive 7- or 14-day moxifloxacin-dexlansoprazole based triple therapy with probiotic or placebo...
October 26, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29066774/role-of-the-luxs-gene-in-bacteriocin-biosynthesis-by-lactobacillus-plantarum-klds1-0391-a-proteomic-analysis
#16
Fang-Fang Jia, Xue-Hui Pang, De-Quan Zhu, Zong-Tao Zhu, Si-Rui Sun, Xiang-Chen Meng
Certain probiotic species of lactic acid bacteria, especially Lactobacillus plantarum, regulate bacteriocin synthesis through quorum sensing (QS) systems. In this study, we aimed to investigate the luxS-mediated molecular mechanisms of QS during bacteriocin synthesis by L. plantarum KLDS1.0391. In the absence of luxS, the 'spot-on-the-lawn' method showed that the bacteriocin production by L. plantarum KLDS1.0391 significantly decreased upon co-cultivation with L. helveticus KLDS1.9207 (P < 0.01) but did not change significantly when mono-cultivated...
October 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29063712/the-possible-causal-relationship-between-fragmentation-of-genomic-dna-and-formation-of-viable-but-non-culturable-probiotic-bacteria-upon-storage-in-dry-state
#17
Marie-Louise R W Hansen, Morten Arendt Ramsussen, Thomas Skov, Anders Clausen, Jens Risbo
In this study, the aim was to establish if loss of DNA integrity is a cause of loss of culturability for probiotic bacteria during storage in dry state. The number of colony forming units (CFU), number of metabolically active cells, and DNA integrity during dry storage of probiotic strains, B. animalis subsp. lactis BB-12 and L. acidophilus LA-5, were investigated. The probiotic strains were freeze-dried and stored at 20°C, with and without oxygen present, and at water activity levels 0.22 or 0.32. Dry storage resulted in a decrease in CFU during the entire storage period...
October 24, 2017: Biotechnology Progress
https://www.readbyqxmd.com/read/29061847/discovery-of-%C3%AE-l-arabinopyranosidases-from-human-gut-microbiome-expands-the-diversity-within-glycoside-hydrolase-family-42
#18
Alexander Holm Viborg, Takane Katayama, Takatoshi Arakawa, Maher Abou Hachem, Leila Lo Leggio, Motomitsu Kitaoka, Birte Svensson, Shinya Fushinobu
Enzymes of the glycoside hydrolase family 42 (GH42) are widespread in bacteria of the human gut microbiome and play fundamental roles in the decomposition of both milk and plant oligosaccharides. All GH42 enzymes characterized so far have β-galactosidase activity. Here, we report the existence of a GH42 subfamily that is exclusively specific for α-L-arabinopyranoside and describe the first representative of this subfamily. We found that this enzyme (BlArap42B) from a probiotic Bifidobacterium species cannot hydrolyze β-galactosides...
October 23, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29061310/dietary-program-and-physical-activity-impact-on-biochemical-markers-in-patients-with-type-2-diabetes-a-systematic-review
#19
Eduarda Barreira, André Novo, Josiana A Vaz, Ana Pereira
OBJECTIVES: Evaluate the effectiveness of the implementation of independently or combined dietary and physical activity programs on the blood glucose values and lipid profile in patients with type 2 diabetes, including participants aged 60 years and over. DESIGN: Systematic review. DATA SOURCE: PubMed/Medline database, with language restrictions. Papers published between 2010 and 2016 were included. STUDY SELECTION: A total of 30 randomised controlled trials were included that focused on physical activity and dietary interventions in patients with type 2 diabetes mellitus and include participants aged 60 years and over...
October 21, 2017: Atencion Primaria
https://www.readbyqxmd.com/read/29056925/host-microbiota-mutualism-in-metabolic-diseases
#20
REVIEW
Salvatore Fabbiano, Nicolas Suárez-Zamorano, Mirko Trajkovski
The intestinal microbiota is a plastic ecosystem that is shaped by environmental and genetic factors, interacting with virtually all tissues of the host. Many signals result from the interplay between the microbiota with its mammalian symbiont that can lead to altered metabolism. Disruptions in the microbial composition are associated with a number of comorbidities linked to the metabolic syndrome. Promoting the niche expansion of beneficial bacteria through diet and supplements can improve metabolic disorders...
2017: Frontiers in Endocrinology
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