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https://www.readbyqxmd.com/read/29157592/the-effects-of-continuous-positive-airway-pressure-therapy-on-troponin-t-and-n-terminal-pro-b-type-natriuretic-peptide-in-patients-with-obstructive-sleep-apnoea-a-randomised-controlled-trial
#1
Ya-Shu Chang, Brendon J Yee, Camilla M Hoyos, Keith K Wong, David R Sullivan, Ronald R Grunstein, Craig L Phillips
INTRODUCTION: Untreated obstructive sleep apnoea (OSA) is associated with increased risk of coronary artery disease (CAD) and heart failure. High-sensitivity cardiac troponin (hs Trop-T) and B-type natriuretic peptide (NT-pro-BNP) are sensitive biomarkers for myocardial injury and heart failure respectively. No randomised controlled trials have examined the treatment effect of continuous positive airway pressure (CPAP) in patients with OSA on these biomarkers. METHOD: Patients >21 years old with apnoea-hypopnoea index (AHI) ≥25/h by overnight polysomnography were recruited...
November 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29155027/serum-level-of-transforming-growth-factor-beta-1-is-associated-with-left-atrial-voltage-in-patients-with-chronic-atrial-fibrillation
#2
Shilu Zhao, Mingfang Li, Weizhu Ju, Lingyun Gu, Fengxiang Zhang, Hongwu Chen, Kai Gu, Bing Yang, Minglong Chen
BACKGROUND: Atrial tissue fibrosis can cause electrical or structural remodeling in patients with atrial fibrillation. Transforming growth factor beta 1(TGF-β1) signaling acts as a central role in fibroblast activation. In this report, we aimed to investigate the relationship between serum level of TGF-β1 and mean left atrial voltage in patients with chronic atrial fibrillation (CAF). METHODS: A total of 16 consecutive adult patients with CAF who underwent catheter ablation were enrolled...
November 15, 2017: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/29154691/optimal-screening-methods-to-detect-cardiac-disorders-in-athletes-an-evidence-based-review
#3
Zachary K Winkelmann, Ashley K Crossway
Reference/Citation:  Harmon KG, Zigman M, Drezner JA. The effectiveness of screening history, physical exam, and ECG to detect potentially lethal cardiac disorders in athletes: a systematic review/meta-analysis. J Electrocardiol. 2015;48(3):329-338. CLINICAL QUESTION:   Which screening method should be considered best practice to detect potentially lethal cardiac disorders during the preparticipation physical examination (PE) of athletes? DATA SOURCES:   The authors completed a comprehensive literature search of MEDLINE, CINAHL, Cochrane Library, Embase, Physiotherapy Evidence Database (PEDro), and SPORTDiscus from January 1996 to November 2014...
November 20, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/29153227/effect-of-changing-the-duration-of-keeping-sandbag-over-catheter-insertion-site-on-the-coronary-angiography-acute-complications-a-controlled-clinical-trial
#4
Mohammad Fathi, Sina Valiee, Parvin Mahmoodi
Transfemoral coronary angiography may cause acute and chronic complications. The aim of the present study was to assess the effects of changing the duration of keeping sandbag over the catheter insertion site on the acute complications of coronary angiography. This quasiexperimental study was conducted on 60 patients undergoing transfemoral coronary angiography. Participants were selected using convenience sampling and were randomly assigned to intervention (n = 30) or control group (n = 30). In the intervention group, the sandbag over the insertion site of catheter was taken off at the third hour, whereas in the control group, based on the routine care, sandbag was taken off at the sixth hour after the angiography...
December 2017: Journal of Vascular Nursing: Official Publication of the Society for Peripheral Vascular Nursing
https://www.readbyqxmd.com/read/29151335/comparison-of-tidal-volume-and-deep-breath-preoxygenation-techniquesundergoing-coronary-artery-bypass-graft-surgery-effects-of-hemodynamicresponse-and-arterial-oxygenation
#5
Zafer Taş, Tülay Hoşten, Alparslan Kuş, Sevim Cesur, Neşe Türkyılmaz, Ahmet Arıkan, Zeynep Mine Solak
Background/aim: Different techniques exist for the preoxygenation of patients that will be operated on under general anesthesia. Preoxygenation with the deep breath (DB) method may affect cardiovascular stability, which is crucial for coronary artery bypass graft (CABG) patients. In this study, we aimed to compare the effects of the 3 min TVB preoxygenation technique and 1 min 8DBs technique on hemodynamic response and arterial oxygenation in patients with normal ejection fraction that were scheduled for elective CABG surgery...
November 13, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29151310/comparison-of-the-cardioprotective-effects-of-dexmedetomidineand-remifentanil-in-cardiac-surgery
#6
Mediha Türktan, Yasemin Güneş, Hafize Yalınız, Selçuk Matyar, Zehra Hatipoğlu, Ersel Güleç, Uğur Göçen, Atakan Atalay
Background/aim: Myocardial protection is an important factor of open heart surgery and biological biomarkers (lactate, CKMB, cardiac troponin I, and pyruvate) are used to assess myocardial damage. This study compares the effects of dexmedetomidine and remifentanil on myocardial protection during coronary artery bypass grafting (CABG) surgery. Materials and methods: Patients scheduled for elective CABG surgery (n = 60) were included in this study. Anesthesia induction was introduced with propofol, fentanyl, and vecuronium bromide...
November 13, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29150530/declining-rates-of-hospitalization-for-selected-cardiovascular-disease-conditions-among-adults-aged-%C3%A2-35-years-with-diagnosed-diabetes-u-s-1998-2014
#7
Nilka Ríos Burrows, YanFeng Li, Edward W Gregg, Linda S Geiss
OBJECTIVE: Reductions in heart attack and stroke hospitalizations are well documented in the U.S. population with diabetes. We extended trend analyses to other cardiovascular disease (CVD) conditions, including stroke by type, and used four additional years of data. RESEARCH DESIGN AND METHODS: Using 1998-2014 National (Nationwide) Inpatient Sample data, we estimated the number of discharges having acute coronary syndrome (ACS) (ICD-9 codes 410-411), cardiac dysrhythmia (427), heart failure (428), hemorrhagic stroke (430-432), or ischemic stroke (433...
November 17, 2017: Diabetes Care
https://www.readbyqxmd.com/read/29145895/comparative-analysis-of-high-sensitivity-cardiac-troponin-i-and-t-for-their-association-with-coronary-computed-tomography-assessed-calcium-scoring-represented-by-the-agatston-score
#8
Jonas Rusnak, Michael Behnes, Thomas Henzler, Nadine Reckord, Nils Vogler, Mathias Meyer, Ursula Hoffmann, Michele Natale, Julia Hoffmann, Sonja Hamed, Kathrin Weidner, Siegfried Lang, Agnibh Mukherji, Holger Haubenreisser, Stefan O Schoenberg, Martin Borggrefe, Thomas Bertsch, Ibrahim Akin
BACKGROUND: This study evaluates the association between high-sensitivity cardiac troponin I (hs-cTnI) and T (hs-cTnT) and coronary calcium concentration (CAC) detected by coronary computed tomography (CCT) and evaluated with the Agatston score in patients with suspected coronary artery disease (CAD). METHODS: Patients undergoing CCT during routine clinical care were enrolled prospectively. CCT was indicated for patients with a low to intermediate pretest probability for CAD...
November 16, 2017: European Journal of Medical Research
https://www.readbyqxmd.com/read/29142551/association-of-single-nucleotide-missence-polymorphism-val109asp-of-omentin-1-gene-and-coronary-artery-disease-in-pakistani-population-multicenter-study
#9
Shazia Nazar, Sitwat Zehra, Abid Azhar
Background & Objective: Coronary artery disease (CAD) is a most important cause of morbidity and mortality worldwide as well as in Pakistan. Recent studies have shown that the combination of obesity, insulin resistance and fluctuation in circulating adipocytokines levels is associated with the pathogenesis of coronary artery disease. Omentin-1 is recently found adipocytokine that is highly expressed in visceral adipose tissue. It has anti- inflammatory properties and is negatively correlated with ischemic heart disease...
September 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29142489/correlation-between-osteoprotegerin-serum-level-and-coronary-calcification-using-coronary-artery-calcium-score-in-patient-with-moderate-severe-cardiovascular-risk-factor
#10
J Nugroho, Widorini Widorini
Coronary artery calcification is a part of atherosclerosis process associated with coronary heart disease. Recently, coronary artery calcification assessment using computed tomography (CT) is still the best noninvasive imaging with high sensitivity and specificity. Osteoprotegerin (OPG) is one of vascular calcification marker that through its role to bind receptor activator of nuclear factor-κβ ligand and inhibit osteoclastogenesis is suspected of playing a role for coronary calcification in atherosclerosis process...
December 2017: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/29142486/vitronectin-and-urokinase-type-plasminogen-activator-gene-expression-levels-are-increased-in-patients-with-coronary-artery-in-stent-restenosis
#11
S M Shafiee, F Noorabad-Ghahroodi, A Amirfarhangi, S R Hosseini-Fard, Z Sharifi, M Najafi
Neointimal hyperplasia is known as a main factor contributing to in-stent restenosis (ISR). Monocytes may play a central role in vessel restenosis process after stent implantation. The aim of this study was to investigate the relationships between the urokinase-type plasminogen activator (PLAU) and vitronectin (Vtn) gene expression levels in peripheral blood mononuclear cell samples isolated from whole blood of 66 patients undergoing coronary artery angiography (22 controls, stenosis < 0.05%; 22 with stent no-restenosis and stenosis < 70%; and 22 with ISR and stenosis > 70%)...
December 2017: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/29140107/a-cross-sectional-study-of-ethnicity-based-differences-in-treatment-seeking-for-symptoms-of-acute-coronary-syndrome
#12
Emma Iacoe, Pamela A Ratner, Sabrina T Wong, Martha H Mackay
BACKGROUND: Patient-related delays in acquiring medical care for symptoms of acute coronary syndrome remain unacceptably long. Many clinical and sociodemographic characteristics associated with treatment-seeking delay are known; however, ethnicity has not been extensively evaluated. OBJECTIVE: The purpose of this study was to examine ethnicity-based differences in the time-to-treatment-seeking intervals of patients experiencing symptoms of acute coronary syndrome...
November 1, 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29139034/vessel-centerline-reconstruction-from-non-isocentric-and-non-orthogonal-paired-monoplane-angiographic-images
#13
Mie Kunio, Caroline C O'Brien, Augusto C Lopes, Lynn Bailey, Pedro A Lemos, Guillermo J Tearney, Elazer R Edelman
PURPOSE: Three-dimensional reconstruction of a vessel centerline from paired planar coronary angiographic images is critical to reconstruct the complex three-dimensional structure of the coronary artery lumen and the relative positioning of implanted devices. In this study, a new vessel centerline reconstruction method that can utilize non-isocentric and non-orthogonal pairs of angiographic images was developed and tested. METHODS: Our new method was developed in in vitro phantom models of bifurcated coronary artery with and without stent, and then tested in in vivo swine models (twelve coronary arteries)...
November 14, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29137693/another-chance-at-life-jordanian-patients-experience-of-going-through-a-myocardial-infarction
#14
Ali Ahmad Ammouri, Joy Kabasindi Kamanyire, Ahmad H Abu Raddaha, Susan Achora, Arwa Atef Obeidat
BACKGROUND AND PURPOSE: Myocardial infarction (MI) is a life-threatening health condition that has physical, spiritual, emotional, and social changes. Understanding feelings and thoughts of patients who suffered MI attacks is essential to recovery. Among Jordanian patients who suffered an acute attack of MI, the aim of the study was to describe the experiences and the varied meanings that they assign to their experiences. METHODS: A qualitative hermeneutic phenomenological research design was used...
November 1, 2017: Research and Theory for Nursing Practice
https://www.readbyqxmd.com/read/29132539/the-diabetic-heart-utilizes-ketone-bodies-as-an-energy-source
#15
Yuji Mizuno, Eisaku Harada, Hitoshi Nakagawa, Yoshinobu Morikawa, Makoto Shono, Fumihito Kugimiya, Michihiro Yoshimura, Hirofumi Yasue
BACKGROUND: Diabetic heart is characterized by failure of insulin to increase glucose uptake and increasingly relies on free fatty acids (FFAs) as a source of fuel in animal models. However, it is not well known how cardiac energy metabolism is altered in diabetic hearts in humans. We examined cardiac fuel metabolism in the diabetics as compared to non-diabetics who underwent cardiac catheterization for heart diseases. MATERIAL AND METHODS: The study subjects comprised 81 patients (male 55, female 26, average age 63...
December 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29132159/aspirin-in-patients-with-previous-percutaneous-coronary-intervention-undergoing-noncardiac-surgery
#16
Michelle M Graham, Daniel I Sessler, Joel L Parlow, Bruce M Biccard, Gordon Guyatt, Kate Leslie, Matthew T V Chan, Christian S Meyhoff, Denis Xavier, Alben Sigamani, Priya A Kumar, Marko Mrkobrada, Deborah J Cook, Vikas Tandon, Jesus Alvarez-Garcia, Juan Carlos Villar, Thomas W Painter, Giovanni Landoni, Edith Fleischmann, Andre Lamy, Richard Whitlock, Yannick Le Manach, Meylin Aphang-Lam, Juan P Cata, Peggy Gao, Nicolaas C S Terblanche, Pamidimukkala V Ramana, Kim A Jamieson, Amal Bessissow, Gabriela R Mendoza, Silvia Ramirez, Pierre A Diemunsch, Salim Yusuf, P J Devereaux
Background: Uncertainty remains about the effects of aspirin in patients with prior percutaneous coronary intervention (PCI) having noncardiac surgery. Objective: To evaluate benefits and harms of perioperative aspirin in patients with prior PCI. Design: Nonprespecified subgroup analysis of a multicenter factorial trial. Computerized Internet randomization was done between 2010 and 2013. Patients, clinicians, data collectors, and outcome adjudicators were blinded to treatment assignment...
November 14, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/29131324/advanced-imaging-reduces-cost-compared-to-standard-of-care-in-emergency-department-of-triage-of-acute-chest-pain
#17
Pamela S Noack, Jhanna A Moore, Michael Poon
OBJECTIVE: To evaluate medical costs of novel therapies in complex medical settings using registry data. DATA SOURCE/STUDY SETTING: Primary data, from 2008 to 2010. We used patient registry data to evaluate cost and quality performance of coronary computed tomography angiography (CCTA) in triaging chest pain patients in our tertiary care emergency department and to model financial performance under Medicare's two midnight rule. STUDY DESIGN: Using generalized linear modeling, we retrospectively compared estimated expenditures for evaluation of low-to-intermediate-risk chest pain for demographic and medically risk matched samples of 894 patients each, triaged with CCTA or local standard of care (SOC) using Medicare reimbursement as a proxy...
November 13, 2017: Health Services Research
https://www.readbyqxmd.com/read/29131290/nesfatin-1-levels-in-patients-with-slow-coronary-flow
#18
Mevlüt Serdar Kuyumcu, Aliye Kuyumcu, Çağrı Yayla, Mustafa Bilal Özbay, Mehmet Alagöz, Sefa Ünal, Burak Açar, Özcan Özeke, Gülhan Samur
BACKGROUND: Nesfatin-1 is a novel found anorectic neuropeptide with potent metabolic regulatory effects. AIM: We aimed to evaluate the relationship between Nesfatin-1 levels and slow coronary flow (SCF). METHODS: A total of 60 consecutive patients with SCF and 60 consecutive patients with the normal coronary flow (NCF) were enrolled into the study. Nesfatin-1 level was measured from blood serum samples using enzyme-linked immunosorbent assay test...
November 13, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/29131079/are-inflammatory-cytokines-associated-with-pain-during-acute-myocardial-infarction
#19
Laurin Imholz, Rebecca E Meister-Langraf, Mary Princip, Michaela Fux, Ulrich Schnyder, Jürgen Barth, Hansjörg Znoj, Jean-Paul Schmid, Roland von Känel
OBJECTIVE: Pain and inflammation during acute myocardial infarction (AMI) have been associated with the development of posttraumatic stress disorder and may also impact negatively on somatic outcome. We investigated the relationship between pain during AMI and levels of circulating proinflammatory (tumor necrosis factor [TNF]-α, interleukin [IL]-6) and anti-inflammatory (IL-33 and tissue growth factor [TGF]-β1) cytokines. METHODS: Data were collected as part of the Myocardial Infarction - Stress Prevention Intervention (MI-SPRINT) study...
November 4, 2017: Neuroimmunomodulation
https://www.readbyqxmd.com/read/29128603/optimal-blood-pressure-control-after-coronary-events-the-challenge-remains
#20
Elise Sverre, Kari Peersen, Jan Erik Otterstad, Lars Gullestad, Joep Perk, Erik Gjertsen, Torbjørn Moum, Einar Husebye, Toril Dammen, John Munkhaugen
We identified sociodemographic, medical, and psychosocial factors associated with unfavorable blood pressure (BP) control in 1012 patients, hospitalized with myocardial infarction and/or a coronary revascularization procedure. This cross-sectional study collected data from hospital records, a comprehensive self-report questionnaire, clinical examination, and blood samples after 2-36 (mean 17) months follow-up. Forty-six percent had unfavorable BP control (≥140/90 [80 in diabetics] mm Hg) at follow-up. Low socioeconomic status and psychosocial factors did not predict unfavorable BP control...
October 28, 2017: Journal of the American Society of Hypertension: JASH
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