keyword
MENU ▼
Read by QxMD icon Read
search

Regenstrief

keyword
https://www.readbyqxmd.com/read/27711982/association-of-anticholinergic-burden-with-cognitive-impairment-and-health-care-utilization-among-a-diverse-ambulatory-older-adult-population
#1
Noll L Campbell, Anthony J Perkins, Pamela Bradt, Sinem Perk, Ronald C Wielage, Malaz A Boustani, Daniel B Ng
STUDY OBJECTIVE: To determine the association between Anticholinergic Cognitive Burden (ACB) score and both cognitive impairment and health care utilization among a diverse ambulatory older adult population. DESIGN: Retrospective cohort study. DATA SOURCE: Medication exposure and other clinical data were extracted from the Regenstrief Medical Record System (RMRS), and cognitive diagnosis derived from a dementia screening and diagnosis study...
October 6, 2016: Pharmacotherapy
https://www.readbyqxmd.com/read/27691375/utilization-and-cost-of-health-care-services-during-the-first-episode-of-psychosis
#2
Emily Liffick, Nicole F Mehdiyoun, Jenifer L Vohs, Michael M Francis, Alan Breier
OBJECTIVE: Because of the chronicity, severity, and marked psychosocial impairment that may characterize the illness, schizophrenia is an incredibly costly disease. Recent data indicate that intervention earlier in the course of schizophrenia produces cost savings. This study compared health service utilization and associated costs for patients receiving treatment for first-episode psychosis (FEP) delivered within the early-intervention (EI) model at the Prevention and Recovery Center for Early Psychosis (PARC) and for a matched sample of FEP patients receiving treatment as usual at a geographically similar mental health clinic...
October 3, 2016: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/27579830/estimated-budget-impact-of-increased-use-of-mirabegron-a-novel-treatment-for-overactive-bladder
#3
Sinem Perk, Ronald C Wielage, Noll L Campbell, Timothy M Klein, Anthony Perkins, Linda M Posta, Thomas Yuran, Robert W Klein, Daniel B Ng
BACKGROUND: Oral pharmacological treatment for overactive bladder (OAB) consists of antimuscarinics and the beta-3 adrenergic agonist mirabegron. Antimuscarinic adverse events (AEs) such as dry mouth, constipation, and blurry vision can result in frequent treatment discontinuation rates, leaving part of the OAB population untreated. Antimuscarinics also contribute to a patient's anticholinergic cognitive burden (ACB), so the Beers Criteria recommends cautious use of antimuscarinics in elderly patients who take multiple anticholinergic medications or have cognitive impairment...
September 2016: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/27574750/estimated-budget-impact-of-increased-use-of-mirabegron-a-novel-treatment-for-overactive-bladder
#4
Sinem Perk, Ronald C Wielage, Noll L Campbell, Timothy M Klein, Anthony Perkins, Linda M Posta, Thomas Yuran, Robert W Klein, Daniel B Ng
BACKGROUND: Oral pharmacological treatment for overactive bladder (OAB) consists of antimuscarinics and the beta-3 adrenergic agonist mirabegron. Antimuscarinic adverse events (AEs) such as dry mouth, constipation, and blurry vision can result in frequent treatment discontinuation rates, leaving part of the OAB population untreated. Antimuscarinics also contribute to a patient's anticholinergic cognitive burden (ACB), so the Beers Criteria recommends cautious use of antimuscarinics in elderly patients who take multiple anticholinergic medications or have cognitive impairment...
September 2016: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/26765453/short-term-medical-costs-of-a-vha-health-information-exchange-a-cheers-compliant-article
#5
COMPARATIVE STUDY
Dustin D French, Brian E Dixon, Susan M Perkins, Laura J Myers, Michael Weiner, Allan J Zillich, David A Haggstrom
The Virtual Lifetime Electronic Record (VLER) Health program provides the Veterans Health Administration (VHA) a framework whereby VHA providers can access the veterans' electronic health record information to coordinate healthcare across multiple sites of care. As an early adopter of VLER, the Indianapolis VHA and Regenstrief Institute implemented a regional demonstration program involving bi-directional health information exchange (HIE) between VHA and non-VHA providers.The aim of the study is to determine whether implementation of VLER HIE reduces 1 year VHA medical costs...
January 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26639793/utilizing-an-integrated-infrastructure-for-outcomes-research-a-systematic-review
#6
REVIEW
Brian E Dixon, Elizabeth C Whipple, John M Lajiness, Michael D Murray
OBJECTIVE: To explore the ability of an integrated health information infrastructure to support outcomes research. METHODS: A systematic review of articles published from 1983 to 2012 by Regenstrief Institute investigators using data from an integrated electronic health record infrastructure involving multiple provider organisations was performed. Articles were independently assessed and classified by study design, disease and other metadata including bibliometrics...
March 2016: Health Information and Libraries Journal
https://www.readbyqxmd.com/read/26262105/building-comprehensive-and-sustainable-health-informatics-institutions-in-developing-countries-moi-university-experience
#7
Martin C Were, Abraham Siika, Paul O Ayuo, Lukoye Atwoli, Fabian Esamai
Current approaches for capacity building in Health Informatics (HI) in developing countries mostly focus on training, and often rely on support from foreign entities. In this paper, we describe a comprehensive and multidimensional capacity-building framework by Lansang & Dennis, and its application for HI capacity building as implemented in a higher-education institution in Kenya. This framework incorporates training, learning-by-doing, partnerships, and centers of excellence. At Moi University (Kenya), the training dimensions include an accredited Masters in HI Program, PhD in HI, and HI short courses...
2015: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/26254699/origins-of-the-arden-syntax
#8
George Hripcsak, Ove B Wigertz, Paul D Clayton
The Arden Syntax originated in the 1980's, when several knowledge-based systems began to show promise, but researchers recognized the burden of recreating these systems at every institution. Derived initially from Health Evaluation through Logical Processing (HELP) and the Regenstrief Medical Record System (RMRS), the Arden Syntax defines medical logic that can be encoded as independent rules, such as reminders and alerts, with the hope of creating a public library of rules. It was first vetted at an informatics retreat held in 1989 at Columbia University's Arden Homestead...
July 2, 2015: Artificial Intelligence in Medicine
https://www.readbyqxmd.com/read/26224334/learning-from-the-crowd-while-mapping-to-loinc
#9
Daniel J Vreeman, John Hook, Brian E Dixon
OBJECTIVE: To describe the perspectives of Regenstrief LOINC Mapping Assistant (RELMA) users before and after the deployment of Community Mapping features, characterize the usage of these new features, and analyze the quality of mappings submitted to the community mapping repository. METHODS: We evaluated Logical Observation Identifiers Names and Codes (LOINC) community members' perceptions about new "wisdom of the crowd" information and how they used the new RELMA features...
November 2015: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/24402119/exploring-a-structural-protein-drug-interactome-for-new-therapeutics-in-lung-cancer
#10
Xiaodong Peng, Fang Wang, Liwei Li, Khuchtumur Bum-Erdene, David Xu, Bo Wang, Anthony A Sinn, Karen E Pollok, George E Sandusky, Lang Li, John J Turchi, Shadia I Jalal, Samy O Meroueh
The pharmacology of drugs is often defined by more than one protein target. This property can be exploited to use approved drugs to uncover new targets and signaling pathways in cancer. Towards enabling a rational approach to uncover new targets, we expand a structural protein-ligand interactome () by scoring the interaction among 1000 FDA-approved drugs docked to 2500 pockets on protein structures of the human genome. This afforded a drug-target network whose properties compared favorably with previous networks constructed using experimental data...
March 4, 2014: Molecular BioSystems
https://www.readbyqxmd.com/read/24373714/regenstrief-institute-s-medical-gopher-a-next-generation-homegrown-electronic-medical-record-system
#11
Jon D Duke, Justin Morea, Burke Mamlin, Douglas K Martin, Linas Simonaitis, Blaine Y Takesue, Brian E Dixon, Paul R Dexter
OBJECTIVE: Regenstrief Institute developed one of the seminal computerized order entry systems, the Medical Gopher, for implementation at Wishard Hospital nearly three decades ago. Wishard Hospital and Regenstrief remain committed to homegrown software development, and over the past 4 years we have fully rebuilt Gopher with an emphasis on usability, safety, leveraging open source technologies, and the advancement of biomedical informatics research. Our objective in this paper is to summarize the functionality of this new system and highlight its novel features...
March 2014: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/24363318/a-multi-part-matching-strategy-for-mapping-loinc-with-laboratory-terminologies
#12
Li-Hui Lee, Anika Groß, Michael Hartung, Der-Ming Liou, Erhard Rahm
OBJECTIVE: To address the problem of mapping local laboratory terminologies to Logical Observation Identifiers Names and Codes (LOINC). To study different ontology matching algorithms and investigate how the probability of term combinations in LOINC helps to increase match quality and reduce manual effort. MATERIALS AND METHODS: We proposed two matching strategies: full name and multi-part. The multi-part approach also considers the occurrence probability of combined concept parts...
September 2014: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/23828174/a-highly-scalable-interoperable-clinical-decision-support-service
#13
Howard S Goldberg, Marilyn D Paterno, Beatriz H Rocha, Molly Schaeffer, Adam Wright, Jessica L Erickson, Blackford Middleton
OBJECTIVE: To create a clinical decision support (CDS) system that is shareable across healthcare delivery systems and settings over large geographic regions. MATERIALS AND METHODS: The enterprise clinical rules service (ECRS) realizes nine design principles through a series of enterprise java beans and leverages off-the-shelf rules management systems in order to provide consistent, maintainable, and scalable decision support in a variety of settings. RESULTS: The ECRS is deployed at Partners HealthCare System (PHS) and is in use for a series of trials by members of the CDS consortium, including internally developed systems at PHS, the Regenstrief Institute, and vendor-based systems deployed at locations in Oregon and New Jersey...
February 2014: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/23670723/assessment-of-case-definitions-for-identifying-acute-liver-injury-in-large-observational-databases
#14
Aaron J Katz, Patrick B Ryan, Judith A Racoosin, Paul E Stang
BACKGROUND: Determining the aetiology of acute liver injury (ALI) may be challenging to both clinicians and researchers. Observational research is particularly useful in studying rare medical outcomes such as ALI; however, case definitions for ALI in previous observational studies lack consistency and sensitivity. ALI is a clinically important condition with various aetiologies, including drug exposure. OBJECTIVE: The aim of this study was to evaluate four distinct case definitions for ALI across a diverse set of large observational databases, providing a better understanding of ALI prevalence and natural history...
August 2013: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/23569586/leveraging-health-information-exchange-to-support-public-health-situational-awareness-the-indiana-experience
#15
Shaun J Grannis, Kevin C Stevens, Ricardo Merriwether
Public health situational awareness is contingent upon timely, comprehensive and accurate information from clinical systems. Ad-hoc models for sending non-standard clinical information directly to public health are inefficient and increasingly unsustainable. Information sharing models that leverage Health Information Exchanges (HIEs) are emerging. HIEs standardize, aggregate and streamline information sharing among data partners, including public health stakeholders, and HIE has supported public health practice in Indiana for more than 10 years...
2010: Online Journal of Public Health Informatics
https://www.readbyqxmd.com/read/22633492/evaluation-of-a-clinical-decision-support-algorithm-for-patient-specific-childhood-immunization
#16
Vivienne J Zhu, Shaun J Grannis, Wanzhu Tu, Marc B Rosenman, Stephen M Downs
OBJECTIVE: To evaluate the effectiveness of a clinical decision support system (CDSS) implementing standard childhood immunization guidelines, using real-world patient data from the Regenstrief Medical Record System (RMRS). METHODS: Study subjects were age 6-years or younger in 2008 and had visited the pediatric clinic on the campus of Wishard Memorial Hospital. Immunization records were retrieved from the RMRS for 135 randomly selected pediatric patients. We compared vaccine recommendations from the CDSS for both eligible and recommended timelines, based on the child's date of birth and vaccine history, to recommendations from registered nurses who routinely selected vaccines for administration in a busy inner city hospital, using the same date of birth and vaccine history...
September 2012: Artificial Intelligence in Medicine
https://www.readbyqxmd.com/read/22306382/auditing-consistency-and-usefulness-of-loinc-use-among-three-large-institutions-using-version-spaces-for-grouping-loinc-codes
#17
M C Lin, D J Vreeman, Clement J McDonald, S M Huff
OBJECTIVES: We wanted to develop a method for evaluating the consistency and usefulness of LOINC code use across different institutions, and to evaluate the degree of interoperability that can be attained when using LOINC codes for laboratory data exchange. Our specific goals were to: (1) Determine if any contradictory knowledge exists in LOINC. (2) Determine how many LOINC codes were used in a truly interoperable fashion between systems. (3) Provide suggestions for improving the semantic interoperability of LOINC...
August 2012: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/22210167/an-approach-to-improve-loinc-mapping-through-augmentation-of-local-test-names
#18
Hyeoneui Kim, Robert El-Kareh, Anupam Goel, F N U Vineet, Wendy W Chapman
Mapping medical test names into a standardized vocabulary is a prerequisite to sharing test-related data between health care entities. One major barrier in this process is the inability to describe tests in sufficient detail to assign the appropriate name in Logical Observation Identifiers, Names, and Codes (LOINC®). Approaches to address mapping of test names with incomplete information have not been well described. We developed a process of "enhancing" local test names by incorporating information required for LOINC mapping into the test names themselves...
August 2012: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/22095034/emerging-perspectives-on-transforming-the-healthcare-system-redesign-strategies-and-a-call-for-needed-research
#19
Bradley N Doebbeling, Mindy E Flanagan
BACKGROUND: U.S. healthcare requires major redesign of its delivery systems, finances, and incentives. Healthcare operations, leadership, and payors are increasingly recognizing the need for community-business-research partnerships to transform healthcare. New models of continuous learning, research, and development should help focus and sustain redesign efforts. PURPOSE: This study summarizes suggested strategies for transformational change in healthcare and identifies needed areas for research to inform, spread, and sustain transformational change...
December 2011: Medical Care
1
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"