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https://www.readbyqxmd.com/read/29447987/escmid-study-group-for-infections-in-compromised-hosts-esgich-consensus-document-on-the-safety-of-targeted-and-biological-therapies-an-infectious-diseases-perspective-soluble-immune-effector-molecules-ii-agents-targeting-interleukins-immunoglobulins-and-complement
#1
REVIEW
Kevin L Winthrop, Xavier Mariette, Jose T Silva, Esther Benamu, Leonard H Calabrese, Alexandre Dumusc, Josef S Smolen, José María Aguado, Mario Fernández-Ruiz
BACKGROUND: The present review is part of the ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies. AIMS: To review, from an Infectious Diseases perspective, the safety profile of agents targeting interleukins, immunoglobulins and complement factors and to suggest preventive recommendations. SOURCES: Computer-based MEDLINE searches with MeSH terms pertaining to each agent or therapeutic family...
February 12, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29425193/accuracy-of-molecular-biology-techniques-for-the-diagnosis-of-strongyloides-stercoralis-infection-a-systematic-review-and-meta-analysis
#2
Dora Buonfrate, Ana Requena-Mendez, Andrea Angheben, Michela Cinquini, Mario Cruciani, Andrea Fittipaldo, Giovanni Giorli, Federico Gobbi, Chiara Piubelli, Zeno Bisoffi
BACKGROUND: Strongyloides stercoralis infection is a neglected tropical disease which can lead to severe symptoms and even death in immunosuppressed people. Unfortunately, its diagnosis is hampered by the lack of a gold standard, as the sensitivity of traditional parasitological tests (including microscopic examination of stool samples and coproculture) is low. Hence, alternative diagnostic methods, such as molecular biology techniques (mostly polymerase chain reaction, PCR) have been implemented...
February 9, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29410653/the-risk-of-chronic-gastrointestinal-disorders-following-acute-infection-with-intestinal-parasites
#3
Jason Blitz, Mark S Riddle, Chad K Porter
Background: Infectious gastroenteritis (IGE) is caused by numerous bacterial, viral, and parasitic pathogens. A history of IGE has been shown in previous studies to increase the risk of developing chronic gastrointestinal disorders and other chronic conditions. As bacteria and viruses represent the majority of pathogen-specific causes of IGE, post-infectious studies have primarily focused on these organisms. The objective of this study was to investigate an association between a history of parasite-associated IGE and the subsequent development of chronic post-infectious gastrointestinal and non-gastrointestinal disorders in a military population...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29388550/leishmania-infantum-dirofilaria-spp-and-other-endoparasite-infections-in-kennel-dogs-in-central-italy
#4
Federica Sauda, Livia Malandrucco, Gladia Macrì, Manuela Scarpulla, Claudio De Liberato, Giuliana Terracciano, Gianluca Fichi, Federica Berrilli, Stefania Perrucci
Prevalence and risk factors of Leishmania infantum, Dirofilaria spp. and other potentially zoonotic or canine-specific endoparasite infections were assessed in 639 kennel dogs from central Italy. To this end, individual blood and fecal samples were examined using parasitological, immunological and molecular techniques. The presence of compatible clinical pictures, as well as age and gender were considered as putative risks factors. To evaluate risk factors, multivariable analysis with logistic regression and univariable analysis with a Chi square test and a Fischer's exact test were performed...
2018: Parasite: Journal de la Société Française de Parasitologie
https://www.readbyqxmd.com/read/29385128/high-prevalence-of-s-stercoralis-infection-among-patients-with-chagas-disease-a-retrospective-case-control-study
#5
Pedro Puerta-Alcalde, Joan Gomez-Junyent, Ana Requena-Mendez, Maria Jesús Pinazo, Miriam José Álvarez-Martínez, Natalia Rodríguez, Joaquim Gascon, Jose Muñoz
BACKGROUND: We evaluate the association between Trypanosoma cruzi infection and strongyloidiasis in a cohort of Latin American (LA) migrants screened for both infections in a non-endemic setting. METHODOLOGY: Case-control study including LA individuals who were systematically screened for T. cruzi infection and strongyloidiasis between January 2013 and April 2015. Individuals were included as cases if they had a positive serological result for Strongyloides stercoralis...
January 31, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29384908/anemia-intractable-vomiting-chronic-diarrhea-and-syndrome-of-inappropriate-antidiuretic-secretion-a-diagnostic-dilemma-disseminated-strongyloidosis-in-a-patient-with-newly-diagnosed-htlv-infection-case-report-and-review-of-literature
#6
Hassan Tariq, Muhammad Umar Kamal, Pavithra Reddy, Bharat Bajantri, Masooma Niazi, Ajsza Matela, Cosmina Zeana, Ariyo Ihimoyan, Anil Dev, Sridhar Chilimuri
RATIONALE: Strongyloidiasis hyperinfection and disseminated disease have high mortality rates due to several complications and early detection of Strongyloides infection is therefore prudent. PATIENT CONCERNS: A 37-year-old male patient came with chronic diarrhea, intractable vomiting and was found to have hyponatremia, and anemia on the initial laboratory tests. DIAGNOSES: Further work up revealed syndrome of inappropriate antidiuretic secretion to be the cause of the hyponatremia in addition to gastrointestinal loses...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29379539/enteric-parasites-can-disturb-leptin-and-adiponectin-levels-in-children
#7
Raida S Yahya, Soha I Awad, Nadeem Kizilbash, Hatim A El-Baz, Gehan Atia
Introduction: Infection by intestinal parasites in childhood may be the main cause of many health-related problems in developed countries such as anemia, anorexia, loss of appetite, retarded growth and development. The aim of the present study was to assess the effect of different intestinal parasites on white adipose tissue hormones. Material and methods: Eighty-one children infected by different parasites and 35 apparently healthy children were enrolled in this study...
January 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29378626/prevalence-and-molecular-characterization-of-strongyloides-stercoralis-giardia-duodenalis-cryptosporidium-spp-and-blastocystis-spp-isolates-in-school-children-in-cubal-western-angola
#8
Elena Dacal, José M Saugar, Aida de Lucio, Marta Hernández-de-Mingo, Elena Robinson, Pamela C Köster, María L Aznar-Ruiz-de-Alegría, Mateu Espasa, Arlette Ninda, Javier Gandasegui, Elena Sulleiro, Milagros Moreno, Fernando Salvador, Israel Molina, Esperanza Rodríguez, David Carmena
BACKGROUND: Human infections by the gastrointestinal helminth Strongyloides stercoralis and the enteric protozoans Giardia duodenalis, Cryptosporidium spp. and Blastocystis spp. are not formally included in the list of 20 neglected tropical diseases prioritised by the World Health Organization. Although largely underdiagnosed and considered of lower public health relevance, these infections have been increasingly demonstrated to cause significant morbidity and even mortality globally, particularly among children living in resource-poor settings...
January 29, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29370166/expanding-molecular-diagnostics-of-helminthiasis-piloting-use-of-the-gpln-platform-for-surveillance-of-soil-transmitted-helminthiasis-and-schistosomiasis-in-ghana
#9
Lucas J Cunningham, John Odoom, Deborah Pratt, Linda Boatemaa, Nana Asante-Ntim, Keren Attiku, Bismarck Banahene, Mike Osei-Atweneboana, Jaco J Verweij, David Molyneux, Russell J Stothard, Emily R Adams
The efforts to control and eradicate polio as a global health burden have been successful to the point where currently only three countries now report endemic polio, and the number of cases of polio continues to decrease. The success of the polio programme has been dependant on a well-developed network of laboratories termed the global polio laboratory network (GPLN). Here we explore collaborative opportunities with the GPLN to target two of the 18 diseases listed as a neglected tropical diseases (NTD) namely soil transmitted helminthiasis (STH) and Schistosomiasis (SCH)...
January 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29367294/evaluation-of-two-dna-extraction-methods-on-the-detection-of-strongyloides-stercoralis-infection
#10
Beatrice Barda, Rahel Wampfler, Somphou Sayasone, Khampheng Phongluxa, Syda Xayavong, Khonsavanh Keoduangsy, Christian Schindler, Jennifer Keiser
INTRODUCTION: Strongyloides stercoralis is present worldwide, but its prevalence is still uncertain, mainly due to the lack of sensitivity of diagnostic methods. Molecular techniques are under development, but a standardized protocol is still unavailable. We compared the sensitivity of real time PCR, using two extraction protocols, with the Baermann technique. MATERIALS AND METHODS: Samples were collected in the framework of the baseline screening of a randomized clinical trial evaluating moxidectin against S...
January 24, 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29363443/a-cross-sectional-study-on-intestinal-parasitic-infections-in-children-in-suburban-public-primary-schools-saraburi-the-central-region-of-thailand
#11
Buravej Assavapongpaiboon, Uthaitip Bunkasem, Vivornpun Sanprasert, Surang Nuchprayoon
Intestinal parasitic infection rate among school-aged children in Thailand has been decreasing. However, certain intestinal parasites remain problematic in some regions. This cross-sectional study was conducted between February and September 2016 in three suburban government primary schools (KK, BR, and HK), Saraburi, Thailand. Stool was collected from 263 asymptomatic subjects (4-15 years old), using simple direct smear, formalin-ether concentration, Boeck and Drbohlav's Locke-Egg-Serum (LES) medium culture, and agar plate culture...
January 22, 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29360939/strongyloidiasis-outside-endemic-areas-long-term-parasitological-and-clinical-follow-up-after-ivermectin-treatment
#12
Silvia A Repetto, Paula Ruybal, Estela Batalla, Carlota López, Vanesa Fridman, Mariela Sierra, Marcelo Radisic, Pablo M Bravo, Marikena G Risso, Stella M González Cappa, Catalina D Alba Soto
Background: Strongyloides stercoralis affects 30-100 million people worldwide. The first-line therapy is ivermectin. Cure is defined as the absence of larvae by parasitological methods 1 year after treatment. To date, no longitudinal parasitological studies for longer periods of time have been conducted to confirm its cure. Here, we evaluated treatment response in long-term follow-up patients with chronic infection using parasitological and molecular methods for larvae or DNA detection...
January 19, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29340309/strongyloides-stercoralis-associated-tip-variant-focal-segmental-glomerulosclerosis
#13
Massini Merzkani, Nupur N Uppal, Daniel W Ross, Pranisha Gautam-Goyal, Prashant Malhotra, Hitesh H Shah, Kenar D Jhaveri, Vivette D D'Agati
No abstract text is available yet for this article.
January 2018: KI Reports
https://www.readbyqxmd.com/read/29329561/strongyloides-stercoralis-and-hookworm-co-infection-spatial-distribution-and-determinants-in-preah-vihear-province-cambodia
#14
Armelle Forrer, Virak Khieu, Fabian Schär, Penelope Vounatsou, Frédérique Chammartin, Hanspeter Marti, Sinuon Muth, Peter Odermatt
BACKGROUND: Strongyloides stercoralis and hookworm are two soil-transmitted helminths (STH) that are highly prevalent in Cambodia. Strongyloides stercoralis causes long-lasting infections and significant morbidity but is largely neglected, while hookworm causes the highest public health burden among STH. The two parasites have the same infection route, i.e. skin penetration. The extent of co-distribution, which could result in potential high co-morbidities, is unknown in highly endemic settings like Cambodia...
January 12, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29301814/eosinophilia-a-marker-of-asymptomatic-strongyloides-infection-in-a-young-patient-with-extrapulmonary-tuberculosis
#15
Hirotomo Yamanashi, Sinsuke Kanbara, Kunihiko Murase, Takahiro Maeda
Strongyloides stercoralis infection is a common and neglected public health problem in many areas of the world. Here we report the case of a 21-year-old woman who emigrated from Cambodia to Japan and presented with swelling of the right supraclavicular region of 2 months' duration. She had no other symptoms. Tuberculous lymphadenitis was diagnosed based on a fine-needle aspiration biopsy of the right supraclavicular lymph node. The laboratory examination revealed mild eosinophilia (eosinophils 1348/µL).S. stercoralis and Hymenolepis nana were detected serologically and in faeces examination...
January 4, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29284005/surveillance-of-strongyloidiasis-in-spanish-in-patients-1998-2014
#16
Moncef Belhassen-García, Montserrat Alonso-Sardón, Angela Martinez-Perez, Cristina Soler, Cristina Carranza-Rodriguez, José Luis Pérez-Arellano, Antonio Muro, Fernando Salvador
BACKGROUND: Strongyloides stercoralis is a parasite that causes strongyloidiasis, a neglected tropical disease. S. stercoralis is a soil-transmitted helminth that is widely distributed in tropical and subtropical regions of the world. Strongyloidiasis can occur without any symptoms or as a chronic infection characterized by mild, unspecific symptoms such as pruritus, abdominal pain or discomfort; respiratory impairment also may manifest as a potentially fatal hyperinfection or disseminated infection...
2017: PloS One
https://www.readbyqxmd.com/read/29260657/impact-of-enhanced-health-interventions-for-united-states-bound-refugees-evaluating-best-practices-in-migration-health
#17
Tarissa Mitchell, Deborah Lee, Michelle Weinberg, Christina Phares, Nicola James, Kittisak Amornpaisarnloet, Lalita Aumpipat, Gretchen Cooley, Anita Davies, Valerie Daw Tin Shwe, Vasil Gajdadziev, Olga Gorbacheva, Chutharat Khwan-Niam, Alexander Klosovsky, Waritorn Madilokkowit, Diana Martin, Naing Zaw Htun Myint, Thi Ngoc Yen Nguyen, Thomas B Nutman, Elise M O'Connell, Luis Ortega, Sugunya Prayadsab, Chetdanai Srimanee, Wasant Supakunatom, Vattanachai Vesessmith, William M Stauffer
With an unprecedented number of displaced persons worldwide, strategies for improving the health of migrating populations are critical. United States-bound refugees undergo a required overseas medical examination to identify inadmissible conditions (e.g., tuberculosis) 2-6 months before resettlement, but it is limited in scope and may miss important, preventable infectious, chronic, or nutritional causes of morbidity. We sought to evaluate the feasibility and health impact of diagnosis and management of such conditions before travel...
December 18, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29242212/nuclear-option-prevents-hyperinfection-in-the-strongyloides-worm-war
#18
Richard John Martin
No abstract text is available yet for this article.
January 2, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29239289/immune-complex-detection-in-saliva-samples-an-innovative-proposal-for-the-diagnosis-of-human-strongyloidiasis
#19
L R Bosqui, A L R Gonçalves, M R F Gonçalves-Pires, W R Pavanelli, I Conchon-Costa, J M Costa-Cruz, I N Costa
Human strongyloidiasis is caused by helminth Strongyloides stercoralis. It has a worldwide distribution, often neglected and cause of severe morbidity. The parasitological diagnosis is hindered by the low and irregular amount of larvae in feces. The goal of the present study was to detect IgG and IgG immune complex using conventional serum samples and saliva as alternative samples. We collected samples from 60 individuals, namely: group I composed of 30 healthy individuals; and group II composed of 30 individuals eliminating S...
December 14, 2017: Parasitology
https://www.readbyqxmd.com/read/29217957/evaluation-of-parasitological-methods-for-the-detection-of-strongyloides-stercoralis-among-individuals-in-selected-health-institutions-in-addis-ababa-ethiopia
#20
Tamirat Hailegebriel, Beyene Petros, Tekola Endeshaw
Background: Strongyloides stercoralis causes chronic intestinal infection that may lead to disseminated disease during immunosuppression. Therefore, efficient diagnostic methods are essential to detect silent and latent infections. The present study was aimed to compare the efficacy of parasitological methods for the detection of S. stercoralis infection. Methods: A cross-sectional study was conducted on 351 subjects (226 HIV positive and 125 HIV negative) from October 2005 to May 2006...
September 2017: Ethiopian Journal of Health Sciences
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