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https://www.readbyqxmd.com/read/29239289/immune-complex-detection-in-saliva-samples-an-innovative-proposal-for-the-diagnosis-of-human-strongyloidiasis
#1
L R Bosqui, A L R Gonçalves, M R F Gonçalves-Pires, W R Pavanelli, I Conchon-Costa, J M Costa-Cruz, I N Costa
Human strongyloidiasis is caused by helminth Strongyloides stercoralis. It has a worldwide distribution, often neglected and cause of severe morbidity. The parasitological diagnosis is hindered by the low and irregular amount of larvae in feces. The goal of the present study was to detect IgG and IgG immune complex using conventional serum samples and saliva as alternative samples. We collected samples from 60 individuals, namely: group I composed of 30 healthy individuals; and group II composed of 30 individuals eliminating S...
December 14, 2017: Parasitology
https://www.readbyqxmd.com/read/29217957/evaluation-of-parasitological-methods-for-the-detection-of-strongyloides-stercoralis-among-individuals-in-selected-health-institutions-in-addis-ababa-ethiopia
#2
Tamirat Hailegebriel, Beyene Petros, Tekola Endeshaw
Background: Strongyloides stercoralis causes chronic intestinal infection that may lead to disseminated disease during immunosuppression. Therefore, efficient diagnostic methods are essential to detect silent and latent infections. The present study was aimed to compare the efficacy of parasitological methods for the detection of S. stercoralis infection. Methods: A cross-sectional study was conducted on 351 subjects (226 HIV positive and 125 HIV negative) from October 2005 to May 2006...
September 2017: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/29217943/intestinal-parasitosis-and-their-associated-factors-among-people-living-with-hiv-at-university-of-gondar-hospital-northwest-ethiopia
#3
Tegegne Eshetu, Getinet Sibhatu, Mohammed Megiso, Abrham Abere, Habtamu Wondifraw Baynes, Belete Biadgo, Ayalew Jejaw Zeleke
Background: Most HIV clients die of AIDS related intestinal parasitic infections rather than due to the HIV infection itself. Therefore, this study was aimed at determining the prevalence of intestinal parasite and their associated factors among HIV/AIDS clients at the University of Gondar Hospital, Northwest Ethiopia. Methods: Institution based cross sectional study was conducted using systematic random sampling technique from March to May 2016. A semi-structured questionnaire was used to collect data...
July 2017: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/29217893/strongyloid-hyperinfection-syndrome-in-a-renal-transplant-recipient
#4
S Sriperumbuduri, K Kalidindi, S Guditi, G Taduri
No abstract text is available yet for this article.
November 2017: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/29203662/methylprednisolone-acetate-induces-and-%C3%AE-7-dafachronic-acid-suppresses-strongyloides-stercoralis-hyperinfection-in-nsg-mice
#5
John B Patton, Sandra Bonne-Année, Jessica Deckman, Jessica A Hess, April Torigian, Thomas J Nolan, Zhu Wang, Steven A Kliewer, Amy C Durham, James J Lee, Mark L Eberhard, David J Mangelsdorf, James B Lok, David Abraham
Strongyloides stercoralis hyperinfection causes high mortality rates in humans, and, while hyperinfection can be induced by immunosuppressive glucocorticoids, the pathogenesis remains unknown. Since immunocompetent mice are resistant to infection with S. stercoralis, we hypothesized that NSG mice, which have a reduced innate immune response and lack adaptive immunity, would be susceptible to the infection and develop hyperinfection. Interestingly, despite the presence of large numbers of adult and first-stage larvae in S...
December 4, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29185612/intestinal-parasites-in-cancer-patients-in-the-south-of-brazil
#6
S Jeske, T F Bianchi, M Q Moura, B Baccega, N B Pinto, M E A Berne, M M Villela
Intestinal parasitic infections in immunocompromised patients can lead to serious complications when not diagnosed and treated early. This study aimed to investigate the frequency of intestinal parasites in cancer patients undergoing chemotherapy in the South of Brazil. Three fecal samples collected from each patient (73 individuals) were processed by Ritchie and Faust techniques and submitted to specific staining methods for intestinal protozoa. A 61.6% parasite and/or commensal positivity was found. Helminths identified were Ascaris lumbricoides (33...
November 27, 2017: Brazilian Journal of Biology, Revista Brasleira de Biologia
https://www.readbyqxmd.com/read/29181423/biliary-strongyloides-stercoralis-with-cholecystitis-and-extensive-portal-vein-thrombosis
#7
Laura M Filkins, David C Gaston, Blaine Mathison, Timothy Smith, Marc Roger Couturier, Ryan D Murphy, Claire Ciarkowski, Kimberly E Hanson, Paloma F Cariello
We report the rare finding of Strongyloides stercoralis rhabditiform larvae in biliary fluid, here associated with cholecystitis and near total portal vein thrombosis. The role of S. stercoralis leading to atypical clinical presentations and difficulty diagnosing strongyloidiasis in such patients with appropriate geographic exposure is discussed.
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29179964/a-case-of-multifocal-medulloblastoma-in-an-adult-patient
#8
Rose Marie Hernández Cancela, Jorge Pombo Otero, Angel Concha-Lopez
Only five cases of multifocal medulloblastoma in the adult have been reported to date. We present a case in a male patient in his 50th decade of life who presented with three extra-axial lesions associated with a parenchymatous lesion of the right middle cerebellar peduncle. Sputum sample examination revealed larvae compatible with strongyloides stercoralis, which was our main differential diagnosis. Histological and immunohistochemical studies revealed the existence of a desmoplastic medulloblastoma.
January 2017: Revista Española de Patología
https://www.readbyqxmd.com/read/29179791/influence-of-parasite-load-on-the-diagnosis-and-occurrence-of-eosinophilia-in-alcoholic-patients-infected-with-strongyloides-stercoralis
#9
M L S Silva, E J Inês, J N Souza, A B S Souza, V M S Dias, L N Oliveira, C M Guimarães, E R Menezes, L G Barbosa, M C M Alves, M C A Teixeira, N M Soares
Alcoholic patients are more susceptible to Strongyloides stercoralis infection. The chronic use of alcohol raises the levels of endogenous corticosteroids, which regulates the development of larvae and stimulates the differentiation of rhabditiform into infective filariform larvae, thus inducing internal autoinfection. Therefore, early diagnosis is important to prevent severe strongyloidiasis. The aim of this study was to evaluate the efficacy of parasitological methods, according to the parasite load and the number of stool samples, for diagnosis of S...
November 28, 2017: Journal of Helminthology
https://www.readbyqxmd.com/read/29174224/spotlight-on-crispr-in-strongyloides-parasitic-nematodes
#10
Jordan D Ward
Parasitic nematodes are biomedically and economically important, but many are genetically intractable which limits our understanding of their molecular and cellular biology. Gang et al. report CRISPR/Cas9 genome editing in parasites of the genus Strongyloides, generating both knock-outs and knock-ins, and demonstrated heritability of the modifications, a crucial advance in the field.
November 23, 2017: Trends in Parasitology
https://www.readbyqxmd.com/read/29173533/strongyloides-westeri-worm-and-egg-counts-in-naturally-infected-young-horses
#11
F L Miller, J L Bellaw, E T Lyons, M K Nielsen
Strongyloides westeri is a threadworm parasite found in the small intestine mainly in foals at up to about 4 months of age. This parasite is associated with small intestinal enteritis and diarrhea as well as skin irritation and a clinical syndrome called "frenzied behavior" due to percutaneous invasion. The aim of this study was to investigate S. westeri parasite burdens in age groups older than the initial lactogenic transmission phase. Secondary aims were to examine the impact of host age and gender on worm burden and egg output in naturally infected foals...
December 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/29168467/temporal-trends-of-intestinal-parasites-in-patients-attending-a-tertiary-care-hospital-in-south-india-a-seven-year-retrospective-analysis
#12
Ira Praharaj, Rajiv Sarkar, Sitara Swarna Rao Ajjampur, Sheela Roy, Gagandeep Kang
BACKGROUND & OBJECTIVES: Intestinal parasitic infections and their associated complications are a major cause of morbidity in the developing world. This retrospective study was done to assess the prevalence of intestinal parasitic infections among patients in a tertiary healthcare setting and to analyze age-, gender- and time-related trends in the prevalence of these intestinal parasites over a seven year period (2006-2012). METHODS: The presence of various intestinal parasites in a tertiary care setting over a seven year period in different age groups was determined by performing routine stool microscopy...
July 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29165212/newly-arrived-african-migrants-to-spain-epidemiology-and-burden-disease
#13
Joaquín Salas-Coronas, María Teresa Cabezas-Fernández, Ana Belén Lozano-Serrano, Manuel Jesús Soriano-Pérez, José Vázquez-Villegas, José Ángel Cuenca-Gómez
The aim of this study is to describe the epidemiological profile, clinical characteristics, and microbiological findings in African immigrants newly arrived to Spain attended at a specialized reference unit from October 2004 to February 2017. A common protocol for the screening of imported and cosmopolitan diseases was designed to evaluate patients with ≤ 12 months of stay in Spain. A total of 523 patients were included in the study, 488 (93.3%) of sub-Saharan origin. A high number of helminthic infections were diagnosed in sub-Saharan patients, including geohelminthiasis (hookworms 14...
November 20, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29160359/gastrointestinal-parasites-in-feral-cats-and-rodents-from-the-fernando-de-noronha-archipelago-brazil
#14
Victor Fernando Santana Lima, Rafael Antonio Nascimento Ramos, Raphael Lepold, João Carlos Gomes Borges, Carlos Diógenes Ferreira, Laura Rinaldi, Giuseppe Cringoli, Leucio Câmara Alves
Gastrointestinal parasites are important pathogens affecting animals, some of them are of medical and veterinary concern. Although the dynamic of parasitic infections is a complex phenomenon that has been studied under experimental conditions, it shows several gaps in knowledge, especially in insular regions where a confined population of animals and parasites co-exists. In this study was assessed the parasitism by endoparasite gastrointestinal in feral cats (n = 37) and rodents (n = 30) from the Fernando de Noronha Archipelago; in addition, the risk of human infection and ecological implications of these findings were discussed...
November 9, 2017: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
https://www.readbyqxmd.com/read/29140240/case-report-strongyloides-stercoralis-hyperinfection-in-a-patient-with-chronic-lymphocytic-leukemia
#15
Richelle Guerrero-Wooley, Ernesto Aranda-Aguirre, Wencheng Li, Aimee Wilkin, Elizabeth Palavecino
Strongyloides stercoralis is an intestinal nematode that can cause disseminated infection in an immunocompromised host. It is most commonly acquired in developing countries. It was previously a common infection in many parts of the United States, particularly in the Appalachian region, but is rarely identified currently. Here, we describe a patient born and raised in Appalachia, with no history of travel outside the United States, who presented with chronic lymphocytic leukemia and S. stercoralis hyperinfection characterized by acute respiratory failure, altered mental status, and extended-spectrum-beta-lactamase Klebsiella pneumoniae bacteremia...
November 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29140233/case-report-a-case-of-recurrent-strongyloides-stercoralis-colitis-in-a-patient-with-multiple-myeloma
#16
Keith Glenn, David A Lindholm, Gregory Meis, Luisa Watts, Nicholas Conger
Strongyloides stercoralis chronic infection is frequently subclinical and thus under-recognized, although its increasing prevalence in nonendemic regions has implications for immunocompromised hosts. We present a 75-year-old male with stage II multiple myeloma who presented with relapse of Strongyloides infection after initial treatment, negative surveillance testing, and subsequent resumption of chemotherapy for his multiple myeloma. The optimal regimen for secondary prophylaxis against recurrent infections is unknown...
November 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29114491/reactive-arthritis-associated-with-strongyloides-stercoralis-report-of-an-uncommon-relation
#17
Srujana Mohanty, Madhusudan Samprathi, Sucheta Parija
No abstract text is available yet for this article.
July 2017: Tropical Parasitology
https://www.readbyqxmd.com/read/29114485/laboratory-diagnosis-of-soil-transmitted-helminthiasis
#18
Sumeeta Khurana, Shveta Sethi
Soil-transmitted helminths (STHs) include, i.e., hookworms (Ancylostoma duodenale, Necator americanus), roundworm (Ascaris lumbricoides), whipworm (Trichuris trichiura) and Strongyloides stercoralis. Globally, around 1.5 billion people are infected with STHs. STHs contribute to significant impairment of mental and physical growth, especially in developing countries. Unfortunately, these infections mostly remain undiagnosed due to lack of trained personnel and appropriate technologies. Intermittent shedding of eggs or larvae further makes the diagnosis difficult...
July 2017: Tropical Parasitology
https://www.readbyqxmd.com/read/29114127/incidence-of-gastrointestinal-nematodes-in-goats-in-and-around-mhow-madhya-pradesh
#19
P Shakya, A K Jayraw, N Jamra, V Agrawal, G P Jatav
Gastrointestinal (GI) parasitism in animals is considered as one of the major problems in India causing recurring economic losses to livestock production system owing to morbidity and mortality. But data pertaining to epidemiology of GI nematodes in goats is meager from Malwa region of Madhya Pradesh. Therefore, the present investigation was carried out to study the incidence of GI nematodes in goats in and around Mhow and accordingly a total of 900 faecal samples of goats were collected from Mhow and its adjoining areas and faecal sample examination revealed the incidence of strongyle, Strongyloides papillosus, Trichuris spp...
December 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/29113595/the-helminth-community-of-a-population-of-rattus-norvegicus-from-an-urban-brazilian-slum-and-the-threat-of-zoonotic-diseases
#20
Ticiana Carvalho-Pereira, Fábio N Souza, Luana R N Santos, Ruth Walker, Arsinoê C Pertile, Daiana S de Oliveira, Gabriel G Pedra, Amanda Minter, Maria Gorete Rodrigues, Thiago C Bahiense, Mitermayer G Reis, Peter J Diggle, Albert I Ko, James E Childs, Eduardo M da Silva, Mike Begon, Federico Costa
Urban slums provide suitable conditions for infestation by rats, which harbour and shed a wide diversity of zoonotic pathogens including helminths. We aimed to identify risk factors associated with the probability and intensity of infection of helminths of the digestive tract in an urban slum population of Rattus norvegicus. Among 299 rats, eleven species/groups of helminths were identified, of which Strongyloides sp., Nippostrongylus brasiliensis and, the human pathogen, Angiostrongylus cantonensis were the most frequent (97, 41 and 39%, respectively)...
November 8, 2017: Parasitology
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