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https://www.readbyqxmd.com/read/28346396/a-pcr-based-molecular-detection-of-strongyloides-stercoralisin-human-stool-samples-from-tabriz-city-iran
#1
Reza Ghasemikhah, Mohammad Amin Tabatabaiefar, Seyed Ali Shariatzadeh, Abbas Shahbazi, Teymour Hazratian
Strongyloides stercoralis is a nematode causing serious infections in immunocompromised patients. In chronically infected patients, the low parasitic content as well as the resemblance of the larvae to several other species make diagnosis basedonmorphology difficult. In the present study, a PCR-based method targeting the internal transcribed sequence 2 (ITS2) of the rDNA region was examined for the molecular detection of S. stercoralis infection from the stool samples. A total of 1800 patients were included...
March 27, 2017: Scientia Pharmaceutica
https://www.readbyqxmd.com/read/28345791/trichoscopic-diagnosis-of-cutaneous-pelodera-strongyloides-infestation-in-a-dog
#2
Rareş G M Căpitan, Chiara Noli
BACKGROUND: Pelodera strongyloides infestation has rarely been reported in dogs. It is a saprophytic free-living nematode, found in moist decaying organic matter, whose L3 larval stages occasionally can invade the skin of dogs and humans. Larvae penetrate the follicular infundibula causing an erythematous and pruritic dermatitis. The disease is usually diagnosed by deep skin scraping or histopathology, with large numbers of parasites readily identified in hair follicles. CASE REPORT: Pelodera strongyloides dermatitis was diagnosed in a six-year-old mixed breed dog presenting with alopecia, erythema and severe pruritus on the ventrum and limbs...
March 27, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28338804/duplications-and-positive-selection-drive-the-evolution-of-parasitism-associated-gene-families-in-the-nematode-strongyloides-papillosus
#3
Praveen Baskaran, Tegegn G Jaleta, Adrian Streit, Christian Rödelsperger
Gene duplication is one major mechanism playing a role in the evolution of phenotypic complexity and in the generation of novel traits. By comparing parasitic and nonparasitic nematodes, a recent study found that the evolution of parasitism in Strongyloididae is associated with a large expansion in the Astacin and CAP gene families.To gain novel insights into the developmental processes in the sheep parasite Strongyloides papillosus, we sequenced transcriptomes of different developmental stages and sexes. Overall, we found that the majority of genes are developmentally regulated and have one-to-one orthologs in the diverged S...
March 2, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/28336269/epidemiology-of-polyparasitism-with-taenia-solium-schistosomes-and-soil-transmitted-helminths-in-the-co-endemic-village-of-malanga-democratic-republic-of-congo
#4
Joule Madinga, Katja Polman, Kirezi Kanobana, Lisette van Lieshout, Eric Brienen, Nicolas Praet, Constantin Kabwe, Sarah Gabriël, Pierre Dorny, Pascal Lutumba, Niko Speybroeck
Helminth co-infections are common in sub-Saharan Africa. However, little is known about the distribution and determinants of co-infections with Taenia solium taeniasis/cysticercosis. Building on a previous community-based study on human cysticercosis in Malanga village, we investigated co-infections with Taenia solium, soil-transmitted helminths (STHs) and Schistosoma spp and associated risk factors in a random subsample of 330 participants. Real time PCR assays were used to detect DNA of soil-transmitted helminths (STHs), T...
March 20, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28331839/enterococcal-meningitis-in-association-with-strongyloides-hyperinfection-syndrome
#5
Kalpesh S Sukhwani, Nitin Bansal, Mamta Soni, Anand Ramamurthy, Ram Gopalakrishnan
INTRODUCTION: Strongyloidiasis can cause hyperinfection or disseminated infection in an immunocompromised host, and is an important factor linked to enterococcal bacteremia and meningitis. CASE REPORTS: We report two cases highlighting the importance of suspecting Strongyloides hyperinfection syndrome in patients with enterococcal meningitis. CONCLUSION: Our cases highlight the importance of suspecting Strongyloides hyperinfection syndrome in cases of community acquired enterococcal bacteremia and meningitis...
March 2017: Germs
https://www.readbyqxmd.com/read/28331018/strongyloides-hyperinfection-syndrome-in-an-immunocompetent-host-resulting-in-bandemia-and-death
#6
Aung Myint, Courtney Chapman, Isabel Almira-Suarez, Nupur Mehta
Strongyloides stercoralis infection is usually asymptomatic but can result in a hyperinfection syndrome, most commonly triggered by acquired or iatrogenic immunosuppression. Here, we present a case of a man aged 60 years originally from a strongyloides endemic area with a medical history of alcohol abuse who presents with strongyloides hyperinfection syndrome (SHS) complicated by partial small bowel obstruction, pulmonary haemorrhage, large bandemia without eosinophilia and cardiac arrest resulting in death...
March 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28316848/strongyloides-hyperinfection-in-a-renal-transplant-patient-always-be-on-the-lookout
#7
Murtaza Mazhar, Ijlal Akbar Ali, Nelson Iván Agudelo Higuita
We present a case of a 71-year-old Vietnamese man with chronic kidney disease secondary to adult polycystic kidney disease. He had been a prisoner of war before undergoing a successful cadaveric renal transplant in the United States. He presented to clinic one year after the transplant with gross hematuria, productive cough, intermittent chills, and weight loss. Long standing peripheral eosinophilia of 600-1200/μL triggered further evaluation. A wet mount of stool revealed Strongyloides stercoralis larvae...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/28279703/limitations-to-the-adoption-of-a-standardized-strongyloides-stercoralis-diagnostic-method-case-study-in-the-caribbean
#8
Jennifer K Ketzis
BACKGROUND: Strongyloides stercoralis is frequently under-diagnosed due to the low sensitivity of common faecal diagnostic methods used in clinical laboratories. This leads to a belief that prevalence is low and that S. stercoralis is not an important soil-transmitted helminth (STH). S. stercoralis diagnostic methods with higher sensitivity are available but often not used. Reasons for their lack of use need to be identified and addressed in order to increase awareness of this neglected parasite...
March 6, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28273080/geospatial-distribution-of-intestinal-parasitic-infections-in-rio-de-janeiro-brazil-and-its-association-with-social-determinants
#9
Clarissa Perez Faria, Graziela Maria Zanini, Gisele Silva Dias, Sidnei da Silva, Marcelo Bessa de Freitas, Ricardo Almendra, Paula Santana, Maria do Céu Sousa
BACKGROUND: Intestinal parasitic infections remain among the most common infectious diseases worldwide. This study aimed to estimate their prevalence and provide a detailed analysis of geographical distribution of intestinal parasites in the metropolitan region of Rio de Janeiro, considering demographic, socio-economic, and epidemiological contextual factors. METHODS/PRINCIPAL FINDINGS: The cross-section survey was conducted among individuals attending the Evandro Chagas National Institute of Infectious Diseases (FIOCRUZ, RJ) during the period from April 2012 to February 2015...
March 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28264908/differences-in-the-importance-of-mast-cells-basophils-ige-and-igg-versus-cd4-t-cells-and-ilc2-cells-in-primary-and-secondary-immunity-to-strongyloides-venezuelensis
#10
Kaori Mukai, Hajime Karasuyama, Kenji Kabashima, Masato Kubo, Stephen J Galli
There is evidence that mast cells, basophils and IgE can contribute to immune responses to parasites, however, the relative importance of these effector elements in parasite immunity is not fully understood. Previous work in Il3-deficient and c-kit mutant Kit(W/W-v) mice indicated that interleukin-3 and c-Kit contribute to expulsion of the intestinal nematode Strongyloides venezuelensis (S.v.) during primary infection. Our findings in mast cell-deficient Kit(W-sh/W-sh) mice and two types of mast cell-deficient mice that have normal c-kit: "Hello Kitty" and MasTRECK mice, confirmed prior work in Kit(W/W-v) mice suggesting that mast cells play an important role in S...
March 6, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28261873/purpuric-lesion-in-an-immunocompromised-patient-a-presentation-of-disseminated-strongyloidiasis
#11
Anelise Damiani da Silva Citrin, Jose Antonio Guzmán, Jefferson Barros, Carlos D'Apparecida Machado-Filho
Strongyloidiasis is a parasitic disease caused by Strongyloides stercoralis, a predominantly intestinal nematode that has human as its main reservoir, broadly distributed worldwide. (1,2,3,4,5,6) The presence of periumbilical purpura is a rare clinical found in disseminated cases, with high morbimortality. (1,2,4) Due to the atypical presentation, we report this case. This article is protected by copyright. All rights reserved.
March 6, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28254204/eosinophilia-associated-with-strongyloides-infection-severe-asthma-and-central-bronchiectasis
#12
Kishan Shah, Denisa Ferastraoaru, Sunit Jariwala
No abstract text is available yet for this article.
February 18, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28246451/gastrointestinal-parasitism-of-goats-in-hilly-region-of-meghalaya-india
#13
Meena Das, R Laha, A Goswami, A Goswami
AIM: The aim of this study was to determine the prevalence of gastrointestinal (GI) parasitic infections in goats of hilly region of Meghalaya. MATERIALS AND METHODS: A total of 834 fecal samples of goats were screened for 1 year (2014-2015) using flotation techniques. RESULTS: The overall prevalence of GI parasitic infections in goats was 28.65%. Season-wise highest infections were recorded during rainy season (34.92%) followed by cool (26...
January 2017: Veterinary World
https://www.readbyqxmd.com/read/28238285/urogenital-schistosomiasis-and-soil-transmitted-helminthiasis-sth-in-cameroon-an-epidemiological-update-at-barombi-mbo-and-barombi-kotto-crater-lakes-assessing-prospects-for-intensified-control-interventions
#14
Suzy J Campbell, J Russell Stothard, Faye O'Halloran, Deborah Sankey, Timothy Durant, Dieudonné Eloundou Ombede, Gwladys Djomkam Chuinteu, Bonnie L Webster, Lucas Cunningham, E James LaCourse, Louis-Albert Tchuem-Tchuenté
BACKGROUND: The crater lakes of Barombi Mbo and Barombi Kotto are well-known transmission foci of schistosomiasis and soil-transmitted helminthiasis having had several important control initiatives previously. To collect contemporary epidemiological information, a cross-sectional survey was undertaken inclusive of: signs and symptoms of disease, individual treatment histories, local water, sanitation and hygiene (WASH)-related factors and malacological surveillance, with molecular characterisation of specimens...
February 27, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28229042/an-investigation-of-parasitic-infections-and-review-of-molecular-characterization-of-the-intestinal-protozoa-in-nonhuman-primates-in-china-from-2009-to-2015
#15
Junqiang Li, Haiju Dong, Rongjun Wang, Fuchang Yu, Yayun Wu, Yankai Chang, Chenrong Wang, Meng Qi, Longxian Zhang
Parasites are a well-known threat to nonhuman primate (NHP) populations, and potentially cause zoonotic diseases in humans. In this study, the basic data was provided of the parasites in NHPs and the molecular characterization of the Enterocytozoon bieneusi, Giardia duodenalis, Cryptosporidium spp., and Entamoeba spp. were reviewed, which were found in these samples. A total of 3349 fecal samples were collected from 34 species reared at 17 districts in zoos, farms, free-range, or research laboratories, and examined microscopically...
April 2017: International Journal for Parasitology. Parasites and Wildlife
https://www.readbyqxmd.com/read/28228914/occurrence-of-intestinal-parasitic-contamination-in-select-consumed-local-raw-vegetables-and-fruits-in-kuantan-pahang
#16
Afzan Mat Yusof, Mardhiah Mohammad, Muna Abshir Abdullahi, Zeehaida Mohamed, Robaiza Zakaria, Ridhwan Abdul Wahab
Intestinal parasitic infections are one of the most common causes of human diseases that result in serious health and economic issues in many developing and developed countries. Raw vegetables and fruits play an important role in transmitting parasites to humans. Hence, the aim of this study was to investigate the parasitological contamination of select commonly consumed local leafy vegetables and fruits in Kuantan, Malaysia. One kilogram of locally consumed raw vegetables and fruits were collected randomly from the Kuantan wet market (Pasar Tani) during the monsoon season (November 2014-January 2015) and the dry season (February 2015-April 2015)...
January 2017: Tropical Life Sciences Research
https://www.readbyqxmd.com/read/28219601/syndrome-of-inappropriate-anti-diuretic-hormone-secretion-secondary-to-strongyloides-stercoralis-infection-in-an-allogeneic-stem-cell-transplant-patient-a-case-report-and-literature-review
#17
M Khushman, M I Morris, L Diaz, M Goodman, D Pereira, K Fuller, M Garcia-Buitrago, B Moshiree, S Zelaya, A Nayer, C L Benjamin, K V Komanduri
Syndrome of inappropriate anti-diuretic hormone (SIADH) has been reported to be associated with systemic Strongyloides stercoralis. Here, we report a case of a stem cell transplant (SCT) recipient who developed severe SIADH secondary to systemic S Stercoralis. The SIADH resolved quickly after treating the systemic S Stercoralis with ivermectin. A systematic review of the literature was performed by PubMed, Scopus, and Cochrane database search. Only eight cases of S Stercoralis in allogeneic SCT recipients have been previously reported...
March 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28219472/immunodiagnosis-of-paramphistomosis-using-monoclonal-antibody-based-sandwich-elisa-for-detection-of-paramphistomum-gracile-circulating-16-kda-antigen
#18
Panat Anuracpreeda, Kullanid Tepsupornkul, Runglawan Chawengkirttikul
In this study, we have produced a monoclonal antibody (MoAb) against 16 kDa antigen of Paramphistomum gracile (16 kDaAgPg), and developed an accurate sandwich enzyme-linked immunosorbent assay (sandwich ELISA) for the detection of circulating 16 kDaAg in the serum and fecal samples from cattle naturally infected with P. gracile. MoAb 1D10 was immobilized on a microtitre plate, and the antigen in the samples was captured and detected with biotinylated rabbit anti-16 kDaAgPg antibody. The lower detection limit of sandwich ELISA was 3·5 pg mL-1, and no cross-reaction with other parasite antigens was evaluated...
February 21, 2017: Parasitology
https://www.readbyqxmd.com/read/28210503/strongyloidiasis-current-status-with-emphasis-in-diagnosis-and-drug-research
#19
REVIEW
Tiago Mendes, Karen Minori, Marlene Ueta, Danilo Ciccone Miguel, Silmara Marques Allegretti
Strongyloidiasis is a parasitic neglected disease caused by the nematode Strongyloides stercoralis affecting 30 to 100 million people worldwide. Complications, strongly associated with alcoholism, organ transplants, and HTLV-1 virus, often arise due to late diagnosis, frequently leading to patient death. Lack of preemptive diagnosis is not the only difficulty when dealing with this parasite, since there are no gold standard diagnostic techniques, and the ones used have problems associated with sensitivity, resulting in false negatives...
2017: Journal of Parasitology Research
https://www.readbyqxmd.com/read/28203368/a-nationwide-survey-of-anthelmintic-treatment-failure-on-sheep-farms-in-ireland
#20
Jason D Keegan, Orla M Keane, Barbara Good, Theo De Waal, Marian Denny, James P Hanrahan, William Fitzgerald, Maresa Sheehan
BACKGROUND: Between 2013 and 2015 the Department of Agriculture, Food and the Marine (DAFM) administered a sheep technology adoption programme (STAP), with the aim of increasing profitability on Irish sheep farms by encouraging the adoption of best management practices. One of the options available to STAP participants was to test the efficacy of the anthelmintic treatment (benzimadazole, levamisole or macrocyclic lactone) used in their flocks by means of a drench test, which is a modification of the faecal egg count reduction test; individual faecal samples were collected from the same group of lambs before and after anthelmintic treatment, the number of eggs present pre and post treatment was subsequently determined from a pooled sample...
2017: Irish Veterinary Journal
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