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https://www.readbyqxmd.com/read/29909498/leisure-participation-patterns-for-school-age-youth-with-autism-spectrum-disorders-findings-from-the-2016-national-survey-of-children-s-health
#1
Karen Ratcliff, Ickpyo Hong, Claudia Hilton
Leisure activity participation is important for health and well-being. This study examined similarities and differences between typically developing children and those with autism spectrum disorders (ASD) from 6 to 17 years old in physical, recreational, social, skill, and jobs/chores activities from a large national database. Findings revealed that children with ASD had significantly lower participation levels than those without ASD between 11 and 17 years old. They suggest an increasing disparity among many types of leisure participation for children and youth with ASD as they age, eventually leading to limited participation in adult activities...
June 16, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29909497/a-retrospective-chart-review-of-children-with-asd-s-individual-education-plans-compared-to-subsequent-independent-psychological-evaluations
#2
Nicholas W Gelbar, Mary Beth Bruder, Emily DeBiase, John D Molteni
The heterogeneity of Autism Spectrum Disorder (ASD) makes it difficult for school-based professionals to develop effective Individual Education Plans (IEP) for this group. Limited research exists on the quality of IEP programs for individuals with ASD. This article summarizes the results of a retrospective chart review from an outpatient diagnostic center. Researchers collected data from IEPs and subsequent psychological evaluations of 75 individuals diagnosed with ASD. The implications of these results for future research and practice are discussed...
June 16, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29907953/effectiveness-of-a-scerts-model-based-intervention-for-children-with-autism-spectrum-disorder-asd-in-hong-kong-a-pilot-study
#3
Lu Yu, Xiaoqin Zhu
A SCERTS model-based intervention with different durations (5-month vs. 10-month) was provided to 122 children with autism spectrum disorder (ASD) (age = 53.43 ± 9.05 months) in Hong Kong. Before and after the intervention, the children were assessed with the Chinese Psychoeducational Profile-Third Edition (CPEP-3) and the Developmental Assessment Chart (DAC). Educators and parents expressed their views toward the intervention in focus groups. Results showed that participating children improved significantly in their social communication and emotional behavior after the intervention, as measured by DAC and CPEP-3...
June 15, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29907738/epigenetic-regulation-of-the-oxytocin-receptor-is-associated-with-neural-response-during-selective-social-attention
#4
Meghan H Puglia, Jessica J Connelly, James P Morris
Aberrant attentional biases to social stimuli have been implicated in a number of disorders including autism and social anxiety disorder. Oxytocin, a naturally-occurring mammalian hormone and neuromodulator involved in regulating social behavior, has been proposed to impact basic biological systems that facilitate the detection of and orientation to social information. Here, we investigate a role for naturally-occurring variability in the endogenous oxytocinergic system in regulating neural response during attention to social information...
June 15, 2018: Translational Psychiatry
https://www.readbyqxmd.com/read/29907643/integrin-activity-in-neuronal-connectivity
#5
REVIEW
Johanna Lilja, Johanna Ivaska
The formation of correct synaptic structures and neuronal connections is paramount for normal brain development and a functioning adult brain. The integrin family of cell adhesion receptors and their ligands play essential roles in the control of several processes regulating neuronal connectivity - including neurite outgrowth, the formation and maintenance of synapses, and synaptic plasticity - that are affected in neurodevelopmental disorders, such as autism spectrum disorders (ASDs) and schizophrenia. Many ASD- and schizophrenia-associated genes are linked to alterations in the genetic code of integrins and associated signalling pathways...
June 15, 2018: Journal of Cell Science
https://www.readbyqxmd.com/read/29906401/school-nurses-increasing-the-compliance-of-hygiene-routines-for-students-with-autism-spectrum-disorder
#6
Constance E McIntosh, Jessica Gundlach, Pamela Brelage, Storey Snyder
School nurses are essential healthcare providers to children with autism spectrum disorder (ASD). In providing this care, school nurses may need to accommodate the unique challenges that children with ASD may face, including but not limited to sensory sensitivities, communicative and social difficulties, difficulties remembering event sequencing and directions, and poor time management skills. The aim of this article is to provide school nurses and healthcare providers evidence-based interventions and strategies that they may use to increase the compliance of hygiene behaviors and routines for children with ASD...
June 1, 2018: NASN School Nurse
https://www.readbyqxmd.com/read/29905970/neurexin-superfamily-cell-membrane-receptor-contactin-associated-protein-like-4-cntnap4-is-involved-in-neural-egfl-like-1-nell-1-responsive-osteogenesis
#7
Chenshuang Li, Zhong Zheng, Pin Ha, Xiaoyan Chen, Wenlu Jiang, Shan Sun, Feng Chen, Greg Asatrian, Emily A Berthiaume, Jong Kil Kim, Eric C Chen, Shen Pang, Xinli Zhang, Kang Ting, Chia Soo
Contactin-associated protein-like 4 (Cntnap4) is a member of the neurexin superfamily of transmembrane molecules that have critical functions in neuronal cell communication. Cntnap4 knockout mice display decreased presynaptic gamma-aminobutyric acid (GABA) and increased dopamine release that is associated with severe, highly penetrant, repetitive, and perseverative movements commonly found in human autism spectrum disorder patients. However, no known function of Cntnap4 has been revealed besides the nervous system...
June 15, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29905666/girls-with-autism-any-sex-based-peculiarities
#8
Ahmed Naguy, Bibi Alamiri
No abstract text is available yet for this article.
June 14, 2018: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/29904907/systematic-review-and-guide-to-management-of-core-and-psychiatric-symptoms-in-youth-with-autism
#9
REVIEW
S H Ameis, C Kassee, P Corbett-Dick, L Cole, S Dadhwal, M-C Lai, J Veenstra-VanderWeele, C U Correll
OBJECTIVE: Evidence-based guidance of clinical decision-making for the management of Autism Spectrum Disorder (ASD) is lacking, particularly for co-occurring psychiatric symptoms. This review evaluates treatment evidence for six common symptom targets in children/adolescents with ASD and provides a resource to facilitate application of the evidence to clinical practice. METHOD: A systematic search identified randomized controlled trials (RCTs) and high-quality systematic reviews published between 2007 and 2016, focused on: social interaction/communication impairment, stereotypic/repetitive behaviours, irritability/agitation, attention-deficit/hyperactivity disorder symptoms, mood or anxiety symptoms, and sleep difficulties...
June 14, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29904648/data-on-social-transmission-of-food-preference-in-a-model-of-autism-induced-by-valproic-acid-and-translational-analysis-of-circulating-microrna
#10
Mauro Mozael Hirsch, Iohanna Deckmann, Mellanie Fontes-Dutra, Guilherme Bauer-Negrini, Gustavo Della-Flora Nunes, Walquiria Nunes, Bruna Rabelo, Rudimar Riesgo, Rogerio Margis, Victorio Bambini-Junior, Carmem Gottfried
This article contains data of Social Transmission of Food Preference in an animal model of autism and the evaluation of a set of microRNA analyzed in autistic patients and animal model of autism. The analyses of the absolute consumption of two flavored food by male rats prenatally exposed to valproic acid (VPA) and treated with resveratrol (RSV), showed that VPA animals show a trend to eat less of the flavored food presented by a demonstrator rat. We also identified 13 microRNA with similar levels among rodents' experimental groups, as well as 11 microRNA with no alterations between autistic and control subjects...
June 2018: Data in Brief
https://www.readbyqxmd.com/read/29904576/genomics-of-autism-spectrum-disorder-approach-to-therapy
#11
REVIEW
Fatma Ayhan, Genevieve Konopka
Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental condition with no current treatment available. Although advances in genetics and genomics have identified hundreds of genes associated with ASD, very little is known about the pathophysiology of ASD and the functional contribution of specific genes to ASD phenotypes. Improved understanding of the biological function of ASD-associated genes and how this heterogeneous group of genetic variants leads to the disease is needed in order to develop therapeutic strategies...
2018: F1000Research
https://www.readbyqxmd.com/read/29904533/using-the-tools-of-informal-science-education-to-connect-science-and-the-public
#12
April Killikelly
Traditional modes of communication within the scientific community, including presentation of data at conferences and in peer-reviewed publications, use technical jargon that limits public engagement. While altering word choice is an important method for increasing public engagement, the data itself may not be enough. For example, communicating the lack of evidence that vaccines cause autism did not convince many reluctant parents to vaccinate their kids (Nyhan, Reifler, Richey, Freed, Pediatrics 133:e835-e842, 2014)...
2018: Journal of Microbiology & Biology Education: JMBE
https://www.readbyqxmd.com/read/29904178/the-phenotypic-spectrum-of-proximal-6q-deletions-based-on-a-large-cohort-derived-from-social-media-and-literature-reports
#13
Aafke Engwerda, Barbara Frentz, A Lya den Ouden, Boudien C T Flapper, Morris A Swertz, Erica H Gerkes, Mirjam Plantinga, Trijnie Dijkhuizen, Conny M A van Ravenswaaij-Arts
Proximal 6q (6q11-q15) deletions are extremely rare and little is known about their phenotypic consequences. Since parents and caregivers now use social media to seek information on rare disorders, the Chromosome 6 Project has successfully collaborated with a Facebook group to collect data on individuals worldwide. Here we describe a cohort of 20 newly identified individuals and 25 literature cases with a proximal 6q deletion. Microarray results and phenotype data were reported directly by parents via a multilingual online questionnaire...
June 8, 2018: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/29903609/building-blocks-of-social-cognition-mirror-mentalize-share
#14
REVIEW
Daniel Alcalá-López, Kai Vogeley, Ferdinand Binkofski, Danilo Bzdok
During the past decade, novel approaches to study social interaction have expanded and questioned long-standing knowledge about how humans understand each other. We aim to portray and reconcile the key psychological processes and neural mechanisms underlying navigation of the social environment. Theoretical accounts mostly revolved around either abstract inferences or embodied simulations, whereas experimental studies mostly focused on theory of mind or mentalizing, empathy, and action imitation. The tension between theories of and experiments on social cognition is systematically revisited to foster new theoretical and empirical studies in the fields...
May 14, 2018: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29903462/has-autism-found-a-place-in-mainstream-tv
#15
Jules Morgan
No abstract text is available yet for this article.
June 11, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/29903454/physiology-of-the-cerebellum
#16
Egidio D'Angelo
The cerebellum is a central brain structure deeply integrated into major loops with the cerebral cortex, brainstem, and spinal cord. The cerebellum shows a complex regional organization consisting of modules with sagittal orientation. The cerebellum takes part in motor control and its lesions cause a movement incoordination syndrome called ataxia. Recent observations also imply involvement of the cerebellum in cognition and executive control, with an impact on pathologies like dyslexia and autism. The cerebellum operates as a forward controller learning to predict the precise timing of correlated events...
2018: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/29902925/the-effect-of-various-high-probability-to-low-probability-instruction-ratios-during-the-use-of-the-high-probability-instructional-sequence
#17
Hallie Ertel, David A Wilder, Ansley Hodges, LeAnn Hurtado
The high-probability (high-p) instructional sequence, which involves the delivery of a series of high-p instructions immediately before delivery of a low-probability (low-p) instruction, is a commonly used procedure to increase compliance among children and individuals with intellectual disabilities. Although the modal ratio of high-p instructions to low-p instructions is 3:1, other ratios may be more effective. In the current study, we compared three ratios of high-p with low-p instructions (i.e., 1:1, 3:1, and 5:1) during use of the high-p instructional sequence to increase compliance among three children with autism...
June 1, 2018: Behavior Modification
https://www.readbyqxmd.com/read/29902778/toxic-metal-loid-based-pollutants-and-their-possible-role-in-autism-spectrum-disorder
#18
REVIEW
Geir Bjørklund, Anatoly V Skalny, Md Mostafizur Rahman, Maryam Dadar, Heba A Yassa, Jan Aaseth, Salvatore Chirumbolo, Margarita G Skalnaya, Alexey A Tinkov
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social interaction, verbal and non-verbal communication, and stereotypic behaviors. Many studies support a significant relationship between many different environmental factors in ASD etiology. These factors include increased daily exposure to various toxic metal-based environmental pollutants, which represent a cause for concern in public health. This article reviews the most relevant toxic metals, commonly found, environmental pollutants, i...
June 11, 2018: Environmental Research
https://www.readbyqxmd.com/read/29902186/no-relationship-between-autistic-traits-and-salivary-testosterone-concentrations-in-men-from-the-general-population
#19
Diana Weiting Tan, Murray T Maybery, Michael W Clarke, Renata Di Lorenzo, Melissa O Evans, Michael Mancinone, Christina Panos, Andrew J O Whitehouse
It is suggested that testosterone may play a part in the higher prevalence of Autism Spectrum Disorder (ASD) in males compared to females. Previous studies have reported elevated postnatal testosterone levels in children and women with ASD but not in men. We compared levels of salivary testosterone across 67 undergraduate males (Mage 19.5 yrs, SD 1.92) selected for low, mid-range and high levels of autistic traits assessed using the Autism-spectrum Quotient. Analyses revealed no significant differences in testosterone concentrations across the three groups...
2018: PloS One
https://www.readbyqxmd.com/read/29902034/autism-spectrum-disorder-in-latin-american-families-experiences-in-chile
#20
Kathrin Hartmann, C Teal Kozikowski, Maria R Urbano, Takeshia V Williams, Caroline Luong-Tran Ba, Alexander Peterkin
INTRODUCTION: The present study provides pilot data investigating relationships between severity of autism spectrum disorder (ASD) traits, community supports, and other family variables as reported by caregivers of children with ASD in Chile. METHOD: An anonymous caregiver survey was developed based on previous ASD survey studies conducted in the United States and direct input from collaborators residing in Chile. Participants included Chilean caregivers of individuals with ASD (N = 50; Mchild age = 6...
June 2018: Families, Systems & Health: the Journal of Collaborative Family Healthcare
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