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https://www.readbyqxmd.com/read/27689173/objective-assessment-of-cervical-stiffness-after-administration-of-misoprostol-for-intrauterine-contraceptive-insertion
#1
S Badir, E Mazza, M Bajka
PURPOSE: The goal of this study was to objectively quantify cervical stiffness in misoprostol users prior to IUC insertion and at follow-up consultation to evaluate the feasibility of assessing cervical stiffness and to study the influence of misoprostol on cervical softening. MATERIALS AND METHODS: This was a cross-sectional study that evaluated 40 women who wished to use the LNG IUS. These women were evaluated immediately before LNG IUS insertion and 6 weeks later at follow-up consultation...
May 2016: Ultrasound International Open
https://www.readbyqxmd.com/read/27651826/using-a-constraint-based-regression-method-for-relative-quantification-of-somatic-mutations-in-pyrosequencing-signals-a-case-for-nras-analysis
#2
Jerome Ambroise, Jamal Badir, Louise Nienhaus, Annie Robert, Anne-France Dekairelle, Jean-Luc Gala
BACKGROUND: Pyrosequencing Allele Quantification (AQ) is a cost-effective DNA sequencing method that can be used for detecting somatic mutations in formalin-fixed paraffin-embedded (FFPE) samples. The method displays a low turnaround time and a high sensitivity. Pyrosequencing suffers however from two main drawbacks including (i) low specificity and (ii) difficult signal interpretation when multiple mutations are reported in a hotspot genomic region. RESULTS: Using a constraint-based regression method, the new AdvISER-PYRO-SMQ algorithm was developed in the current study and implemented into an R package...
2016: Algorithms for Molecular Biology: AMB
https://www.readbyqxmd.com/read/27387466/total-breast-reconstruction-with-fat-grafting-after-internal-expansion-and-expander-removal
#3
Andrea Manconi, Francesca De Lorenzi, Badir Chahuan, Valeria Berrino, Pietro Berrino, Gustavo Zucca-Matthes, Jean Yves Petit, Mario Rietjens
INTRODUCTION: The development of fat grafting techniques both in cosmetic and reconstructive breast surgery has highlighted the need to recreate a breast mound using similar tissues and without visible scarring. Our technique combines skin expansion by conventional expanders and breast volume replacement by serial fat grafting and final expander removal. MATERIALS AND METHODS: Fat grafting had been performed both by Coleman technique and Bodyjet system. We report a series of 12 cases enrolled between 2008 and 2013...
July 6, 2016: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/27359473/water-pipe-smoking-among-young-arabic-high-school-girls-218-board-55-june-1-9-30-am-11-00-am
#4
Daniel S Moran, Maysoon Essa, Halima Badir
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27046271/correction-experimental-treatment-with-favipiravir-for-ebola-virus-disease-the-jiki-trial-a-historically-controlled-single-arm-proof-of-concept-trial-in-guinea
#5
Daouda Sissoko, Cedric Laouenan, Elin Folkesson, Abdoul-Bing M'Lebing, Abdoul-Habib Beavogui, Sylvain Baize, Alseny-Modet Camara, Piet Maes, Susan Shepherd, Christine Danel, Sara Carazo, Mamoudou N Conde, Jean-Luc Gala, Géraldine Colin, Hélène Savini, Joseph Akoi Bore, Frederic Le Marcis, Fara Raymond Koundouno, Frédéric Petitjean, Marie-Claire Lamah, Sandra Diederich, Alexis Tounkara, Geertrui Poelart, Emmanuel Berbain, Jean-Michel Dindart, Sophie Duraffour, Annabelle Lefevre, Tamba Leno, Olivier Peyrouset, Léonid Irenge, N'Famara Bangoura, Romain Palich, Julia Hinzmann, Annette Kraus, Thierno Sadou Barry, Sakoba Berette, André Bongono, Mohamed Seto Camara, Valérie Chanfreau Munoz, Lanciné Doumbouya, Souley Harouna, Patient Mumbere Kighoma, Fara Roger Koundouno, Réné Lolamou, Cécé Moriba Loua, Vincent Massala, Kinda Moumouni, Célia Provost, Nenefing Samake, Conde Sekou, Abdoulaye Soumah, Isabelle Arnould, Michel Saa Komano, Lina Gustin, Carlotta Berutto, Diarra Camara, Fodé Saydou Camara, Joliene Colpaert, Léontine Delamou, Lena Jansson, Etienne Kourouma, Maurice Loua, Kristian Malme, Emma Manfrin, André Maomou, Adele Milinouno, Sien Ombelet, Aboubacar Youla Sidiboun, Isabelle Verreckt, Pauline Yombouno, Anne Bocquin, Caroline Carbonnelle, Thierry Carmoi, Pierre Frange, Stéphane Mely, Vinh-Kim Nguyen, Delphine Pannetier, Anne-Marie Taburet, Jean-Marc Treluyer, Jacques Kolie, Raoul Moh, Minerva Cervantes Gonzalez, Eeva Kuisma, Britta Liedigk, Didier Ngabo, Martin Rudolf, Ruth Thom, Romy Kerber, Martin Gabriel, Antonino Di Caro, Roman Wölfel, Jamal Badir, Mostafa Bentahir, Yann Deccache, Catherine Dumont, Jean-François Durant, Karim El Bakkouri, Marie Gasasira Uwamahoro, Benjamin Smits, Nora Toufik, Stéphane Van Cauwenberghe, Khaled Ezzedine, Eric D'Ortenzio, Louis Pizarro, Aurélie Etienne, Jérémie Guedj, Alexandra Fizet, Eric Barte de Sainte Fare, Bernadette Murgue, Tuan Tran-Minh, Christophe Rapp, Pascal Piguet, Marc Poncin, Bertrand Draguez, Thierry Allaford Duverger, Solenne Barbe, Guillaume Baret, Isabelle Defourny, Miles Carroll, Hervé Raoul, Augustin Augier, Serge P Eholie, Yazdan Yazdanpanah, Claire Levy-Marchal, Annick Antierrens, Michel Van Herp, Stephan Günther, Xavier de Lamballerie, Sakoba Keïta, France Mentre, Xavier Anglaret, Denis Malvy
[This corrects the article DOI: 10.1371/journal.pmed.1001967.].
April 2016: PLoS Medicine
https://www.readbyqxmd.com/read/26930627/experimental-treatment-with-favipiravir-for-ebola-virus-disease-the-jiki-trial-a-historically-controlled-single-arm-proof-of-concept-trial-in-guinea
#6
Daouda Sissoko, Cedric Laouenan, Elin Folkesson, Abdoul-Bing M'Lebing, Abdoul-Habib Beavogui, Sylvain Baize, Alseny-Modet Camara, Piet Maes, Susan Shepherd, Christine Danel, Sara Carazo, Mamoudou N Conde, Jean-Luc Gala, Géraldine Colin, Hélène Savini, Joseph Akoi Bore, Frederic Le Marcis, Fara Raymond Koundouno, Frédéric Petitjean, Marie-Claire Lamah, Sandra Diederich, Alexis Tounkara, Geertrui Poelart, Emmanuel Berbain, Jean-Michel Dindart, Sophie Duraffour, Annabelle Lefevre, Tamba Leno, Olivier Peyrouset, Léonid Irenge, N'Famara Bangoura, Romain Palich, Julia Hinzmann, Annette Kraus, Thierno Sadou Barry, Sakoba Berette, André Bongono, Mohamed Seto Camara, Valérie Chanfreau Munoz, Lanciné Doumbouya, Souley Harouna, Patient Mumbere Kighoma, Fara Roger Koundouno, Réné Lolamou, Cécé Moriba Loua, Vincent Massala, Kinda Moumouni, Célia Provost, Nenefing Samake, Conde Sekou, Abdoulaye Soumah, Isabelle Arnould, Michel Saa Komano, Lina Gustin, Carlotta Berutto, Diarra Camara, Fodé Saydou Camara, Joliene Colpaert, Léontine Delamou, Lena Jansson, Etienne Kourouma, Maurice Loua, Kristian Malme, Emma Manfrin, André Maomou, Adele Milinouno, Sien Ombelet, Aboubacar Youla Sidiboun, Isabelle Verreckt, Pauline Yombouno, Anne Bocquin, Caroline Carbonnelle, Thierry Carmoi, Pierre Frange, Stéphane Mely, Vinh-Kim Nguyen, Delphine Pannetier, Anne-Marie Taburet, Jean-Marc Treluyer, Jacques Kolie, Raoul Moh, Minerva Cervantes Gonzalez, Eeva Kuisma, Britta Liedigk, Didier Ngabo, Martin Rudolf, Ruth Thom, Romy Kerber, Martin Gabriel, Antonino Di Caro, Roman Wölfel, Jamal Badir, Mostafa Bentahir, Yann Deccache, Catherine Dumont, Jean-François Durant, Karim El Bakkouri, Marie Gasasira Uwamahoro, Benjamin Smits, Nora Toufik, Stéphane Van Cauwenberghe, Khaled Ezzedine, Eric D'Ortenzio, Eric Dortenzio, Louis Pizarro, Aurélie Etienne, Jérémie Guedj, Alexandra Fizet, Eric Barte de Sainte Fare, Bernadette Murgue, Tuan Tran-Minh, Christophe Rapp, Pascal Piguet, Marc Poncin, Bertrand Draguez, Thierry Allaford Duverger, Solenne Barbe, Guillaume Baret, Isabelle Defourny, Miles Carroll, Hervé Raoul, Augustin Augier, Serge P Eholie, Yazdan Yazdanpanah, Claire Levy-Marchal, Annick Antierrens, Michel Van Herp, Stephan Günther, Xavier de Lamballerie, Sakoba Keïta, France Mentre, Xavier Anglaret, Denis Malvy
BACKGROUND: Ebola virus disease (EVD) is a highly lethal condition for which no specific treatment has proven efficacy. In September 2014, while the Ebola outbreak was at its peak, the World Health Organization released a short list of drugs suitable for EVD research. Favipiravir, an antiviral developed for the treatment of severe influenza, was one of these. In late 2014, the conditions for starting a randomized Ebola trial were not fulfilled for two reasons. One was the perception that, given the high number of patients presenting simultaneously and the very high mortality rate of the disease, it was ethically unacceptable to allocate patients from within the same family or village to receive or not receive an experimental drug, using a randomization process impossible to understand by very sick patients...
March 2016: PLoS Medicine
https://www.readbyqxmd.com/read/26845420/standardizing-handoff-communication-content-analysis-of-27-handoff-mnemonics
#7
Mahiyar F Nasarwanji, Aysel Badir, Ayse P Gurses
This study synthesizes information contained in 27 mnemonics to identify what information should be communicated during a handoff. Clustering and content analysis resulted in 12 primary information clusters that should be communicated. Given the large amount of information identified, it would be beneficial to use a structured handoff communication tool developed using a participatory approach. In addition, we recommend local standardization of information communicated during handoffs with variation across settings...
July 2016: Journal of Nursing Care Quality
https://www.readbyqxmd.com/read/26840883/relationship-between-nurses-practice-environments-and-nursing-outcomes-in-turkey
#8
I Topçu, E Türkmen, A Badır, N Göktepe, M Miral, S Albayrak, A Kebapçı, Ş Serbest, D Özcan
AIM: This study aimed to understand nursing practice environment characteristics in Istanbul-area hospitals in Turkey, the relationship between these characteristics, nurse burnout levels and nurses' intentions to leave work. BACKGROUND: A well-known relationship exists in many countries between nursing practice environments and nurse burnout and intention to leave work. However, little is known about the relationship between practice environment characteristics and nursing outcomes in Turkey...
June 2016: International Nursing Review
https://www.readbyqxmd.com/read/26717206/o-alkylhydroxylamines-as-rationally-designed-mechanism-based-inhibitors-of-indoleamine-2-3-dioxygenase-1
#9
William P Malachowski, Maria Winters, James B DuHadaway, Ariel Lewis-Ballester, Shorouk Badir, Jenny Wai, Maisha Rahman, Eesha Sheikh, Judith M LaLonde, Syun-Ru Yeh, George C Prendergast, Alexander J Muller
Indoleamine 2,3-dioxygenase-1 (IDO1) is a promising therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune suppression. Recently important advances have been made in understanding IDO1's catalytic mechanism. Although much remains to be discovered, there is strong evidence that the mechanism proceeds through a heme-iron bound alkylperoxy transition or intermediate state. Accordingly, we explored stable structural mimics of the alkylperoxy species and provide evidence that such structures do mimic the alkylperoxy transition or intermediate state...
January 27, 2016: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/26085458/fundus-thickness-assessment-by-3d-transvaginal-ultrasound-allows-metrics-based-diagnosis-and-treatment-of-congenital-uterine-anomalies
#10
M Bajka, S Badir
Purpose: The development of a metric fundus assessment and definition of the uterine fundus thickness (FTH) for supporting objective diagnosis and treatment of congenital uterine anomalies (CUAs). Materials and Methods: A) In a prospective cohort study, FTH was systematically assessed by 3 D transvaginal ultrasound (TVS) in patients, who presented a normal uterus. B) The mean normal FTH recorded was applied to uteri with fundal protrusions and septations, and compared to two CUA classification systems (ASF and ESHRE/ESGE)...
June 17, 2015: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/25943254/turkish-critical-care-nurses-views-on-end-of-life-decision-making-and-practices
#11
Aysel Badır, İbrahim Topçu, Emine Türkmen, Nilgün Göktepe, Mukaddes Miral, Nermin Ersoy, Esra Akın
BACKGROUND: Life-sustaining treatments are increasingly used in intensive care units (ICUs) for EOL care, but the decision to use these may cause ethical issues. AIMS AND OBJECTIVES: The aim of this study was to investigate the views and practices of critical care nurses in Turkey on the end-of-life (EOL) care. DESIGN: This was a cross-sectional study. METHODS: The research was conducted in 32 second- and third-level ICUs of 19 Ministry of Health research hospitals in Turkey...
May 6, 2015: Nursing in Critical Care
https://www.readbyqxmd.com/read/25791058/challenging-the-in-vivo-assessment-of-biomechanical-properties-of-the-uterine-cervix-a-critical-analysis-of-ultrasound-based-quasi-static-procedures
#12
M M Maurer, S Badir, M Pensalfini, M Bajka, P Abitabile, R Zimmermann, E Mazza
Measuring the stiffness of the uterine cervix might be useful in the prediction of preterm delivery, a still unsolved health issue of global dimensions. Recently, a number of clinical studies have addressed this topic, proposing quantitative methods for the assessment of the mechanical properties of the cervix. Quasi-static elastography, maximum compressibility using ultrasound and aspiration tests have been applied for this purpose. The results obtained with the different methods seem to provide contradictory information about the physiologic development of cervical stiffness during pregnancy...
June 25, 2015: Journal of Biomechanics
https://www.readbyqxmd.com/read/25693075/using-high-fidelity-simulation-as-a-learning-strategy-in-an-undergraduate-intensive-care-course
#13
Aysel Badir, Zuhal Zeybekoğlu, Pelin Karacay, Nilgün Göktepe, Serpil Topcu, Begüm Yalcin, Ayda Kebapci, Gül Oban
Using high-fidelity simulations to facilitate student learning is an uncommon practice in Turkish nursing programs. The aim of the present study was to understand students' perceptions of the use of simulation in nursing courses. Subjects included 36 senior nursing students taking an intensive care course. This study revealed that high-fidelity simulation is an ideal method of promoting learning by helping students transfer theory into practice, build confidence and teamwork, and raise professional awareness...
March 2015: Nurse Educator
https://www.readbyqxmd.com/read/25028829/appropriate-use-of-magnetic-resonance-imaging-and-ultrasound-to-detect-early-silicone-gel-breast-implant-rupture-in-postmastectomy-reconstruction
#14
COMPARATIVE STUDY
Mario Rietjens, Gaetano Villa, Antonio Toesca, Stefania Rizzo, Sara Raimondi, Fabio Rossetto, Claudia Sangalli, Francesca De Lorenzi, Andrea Manconi, Angelo Gustavo, Zucca Matthes, Badir Chahuan, Fabricio Brenelli, Massimo Bellomi, Jean Yves Petit
BACKGROUND: Implant rupture is one of the most important sequelae of breast reconstruction after mastectomy. The primary aim of this study was to compare magnetic resonance imaging and ultrasound evaluation with intraoperative findings and provide a reliable description of the occurrence of each radiological sign. METHODS: The authors prospectively recruited a consecutive series of 102 postmastectomy patients requiring implant change for aesthetic purposes. Magnetic resonance imaging and ultrasound evaluation results were compared with intraoperative findings...
July 2014: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/24982434/knowledge-of-cardiovascular-disease-in-turkish-undergraduate-nursing-students
#15
Aysel Badir, Kader Tekkas, Serpil Topcu
BACKGROUND: Cardiovascular disease is the number one cause of death worldwide. However, there is not enough data exploring student nurses' understanding, knowledge, and awareness of cardiovascular disease. AIMS: To investigate knowledge of cardiovascular disease and its risk factors among undergraduate nursing students, with an emphasis on understanding of cardiovascular disease as the primary cause of mortality and morbidity, both in Turkey and worldwide. METHODS: This cross-sectional survey assessed 1138 nursing students enrolled in nursing schools in Istanbul, Turkey...
October 2015: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/24620995/a-matter-of-time-rapid-motor-memory-stabilization-in-childhood
#16
Esther Adi-Japha, Rodayna Badir, Shoshi Dorfberger, Avi Karni
Are children better than adults in acquiring new skills ('how-to' knowledge) because of a difference in skill memory consolidation? Here we tested the proposal that, as opposed to adults, children's memories for newly acquired skills are immune to interference by subsequent experience. The establishment of long-term memory for a trained movement sequence in adults requires a phase of memory consolidation. This results in substantial delayed, 'offline', performance gains, which nevertheless remain susceptible to interference by subsequent competing motor experience for several hours after training, unless sleep is afforded in the interval...
May 2014: Developmental Science
https://www.readbyqxmd.com/read/24312770/design-of-vancomycin-rs-100-nanoparticles-in-order-to-increase-the-intestinal-permeability
#17
Badir Delf Loveymi, Mitra Jelvehgari, Parvin Zakeri-Milani, Hadi Valizadeh
PURPOSE: The purpose of this work was to preparation of vancomycin (VCM) biodegradable nanoparticles to improve the intestinal permeability, using water-in-oil-in-water (W/O/W) multiple emulsion method. METHODS: The vancomycin-loaded nanoparticles were created using double-emulsion solvent evaporation method. Using Eudragit RS100 as a coating material. The prepared nanoparticles were identifyed for their micromeritic and crystallographic properties, drug loading, particle size, drug release, Zeta potential, effective permeability (Peff) and oral fractional absorption...
2012: Advanced Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/24250531/statistical-optimization-of-oral-vancomycin-eudragit-rs-nanoparticles-using-response-surface-methodology
#18
Badir Delf Loveymi, Mitra Jelvehgari, Parvin Zakeri-Milani, Hadi Valizadeh
A Box-Behnken design with three replicates was used for preparation and evaluation of Eudragit vancomycin (VCM) nanoparticles prepared by double emulsion. The purpose of this work was to optimize VCM nanoparticles to improve the physicochemical properties. Nanoparticles were formed by using W1/O/W2 double-emulsion solvent evaporation method using Eudragit RS as a retardant material. Full factorial design was employed to study the effect of independent variables, RPM (X1), amount of emulsifier (X2), stirring rate (X3), volume of organic phase (X4) and volume of aqueous phase (X5), on the dependent variables as production yield, encapsulation efficiency and particle size...
2012: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/24250377/preparation-and-determination-of-drug-polymer-interaction-and-in-vitro-release-of-mefenamic-acid-microspheres-made-of-celluloseacetate-phthalate-and-or-ethylcellulose-polymers
#19
Mitra Jelvehgari, Davoud Hassanzadeh, Farhad Kiafar, Badir Delf Loveym, Sara Amiri
The objective of this study was to formulate and evaluate the drug-polymer interaction of mefenamic acid (MA) using two polymers with different characteristics as ethylcellulose (EC) and/or cellulose acetate phthalate (CAP). Microspheres were prepared by the modified emulsion solvent evaporation (MESE). The effect of drug-polymer interaction was studied for each of microspheres. Important parameters in the evaluation of a microencapsulation technique are encapsulation efficiency, yield production, particle size, surface characteristics of microspheres, scanning electronic microscopy (SEM), powder X-ray diffraction analysis (XRD), and differential scanning calorimetry (DSC)...
2011: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/23892845/effect-of-antihypertensive-therapy-with-alpha-methyldopa-on-umbilical-artery-doppler-in-pregnancies-with-hypertensive-disorders
#20
Bedrana Muračević, Jasmin Hodžić, Jamal Badir, Lejla Muhamedagić
Aim To clarify whether applying alpha-methyldopa treatment influences flow resistance in umbilical cord artery in pregnant women suffering from hypertensive disorder. Methods In this prospective cross-sectional study a follow-up was done for 50 pregnant women with singleton pregnancies between 36 and 40 gestation weeks, who had been hospitalized at the Gynecology and Obstetrics Department of the Cantonal Hospital Zenica, Bosnia and Herzegovina from October 2009 to January 2012. Pregnant women were classified in two groups according to the level of using alpha-methyldopa in the treatment...
August 2013: Medicinski Glasnik
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