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https://www.readbyqxmd.com/read/29328703/asymptotic-one-point-functions-in-gauge-string-duality-with-defects
#1
Isak Buhl-Mortensen, Marius de Leeuw, Asger C Ipsen, Charlotte Kristjansen, Matthias Wilhelm
We take the first step in extending the integrability approach to one-point functions in AdS/dCFT to higher loop orders. More precisely, we argue that the formula encoding all tree-level one-point functions of SU(2) operators in the defect version of N=4 supersymmetric Yang-Mills theory, dual to the D5-D3 probe-brane system with flux, has a natural asymptotic generalization to higher loop orders. The asymptotic formula correctly encodes the information about the one-loop correction to the one-point functions of nonprotected operators once dressed by a simple flux-dependent factor, as we demonstrate by an explicit computation involving a novel object denoted as an amputated matrix product state...
December 29, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29307192/enrofloxacin-permeation-pathways-across-the-porin-ompc
#2
Jigneshkumar Dahyabhai Prajapati, Carlos José Fernández Solano, Mathias Winterhalter, Ulrich Kleinekathöfer
In Gram-negative bacteria, the lack or quenching of antibiotics translocation across the outer membrane is one of the main factors for acquiring antibiotic resistance. An atomic level comprehension of the key features governing the transport of drugs by outer membrane protein channels will be very helpful in developing the next generation of antibiotics. In a previous study [J. D. Prajapati et al, J. Chem. Theory Comput. 2017, 13, 4553--4566], we characterized the diffusion pathway of the ciprofloxacin molecule through the outer membrane porin OmpC of E...
January 6, 2018: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/29286820/recognizing-axionic-dark-matter-by-compton-and-de-broglie-scale-modulation-of-pulsar-timing
#3
Ivan De Martino, Tom Broadhurst, S-H Henry Tye, Tzihong Chiueh, Hsi-Yu Schive, Ruth Lazkoz
Light axionic dark matter, motivated by string theory, is increasingly favored for the "no weakly interacting massive particle era". Galaxy formation is suppressed below a Jeans scale of ≃10^{8}  M_{⊙} by setting the axion mass to m_{B}∼10^{-22}  eV, and the large dark cores of dwarf galaxies are explained as solitons on the de Broglie scale. This is persuasive, but detection of the inherent scalar field oscillation at the Compton frequency ω_{B}=(2.5  months)^{-1}(m_{B}/10^{-22}  eV) would be definitive...
December 1, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29216433/aging-jamming-and-the-limits-of-stability-of-amorphous-solids
#4
Vassiliy Lubchenko, Peter G Wolynes
Apart from not having crystallized, supercooled liquids can be considered as being properly equilibrated and thus can be described by a few thermodynamic control variables. In contrast, glasses and other amorphous solids can be arbitrarily far away from equilibrium and require a description of the history of the conditions under which they formed. In this paper we describe how the locality of interactions intrinsic to finite-dimensional systems affects the stability of amorphous solids far off equilibrium. Our analysis encompasses both structural glasses formed by cooling and colloidal assemblies formed by compression...
December 7, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/29197663/prediction-of-potential-drivers-connecting-different-dysfunctional-levels-in-lung-adenocarcinoma-via-a-protein-protein-interaction-network
#5
Fei Yuan, WenCong Lu
Lung cancer is a serious disease that threatens an affected individual's life. Its pathogenesis has not yet to be fully described, thereby impeding the development of effective treatments and preventive measures. "Cancer driver" theory considers that tumor initiation can be associated with a number of specific mutations in genes called cancer driver genes. Four omics levels, namely, (1) methylation, (2) microRNA, (3) mutation, and (4) mRNA levels, are utilized to cluster cancer driver genes. In this study, the known dysfunctional genes of these four levels were used to identify novel driver genes of lung adenocarcinoma, a subtype of lung cancer...
November 29, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29195281/thermodynamic-framework-for-information-in-nanoscale-systems-with-memory
#6
J Ricardo Arias-Gonzalez
Information is represented by linear strings of symbols with memory that carry errors as a result of their stochastic nature. Proofreading and edition are assumed to improve certainty although such processes may not be effective. Here, we develop a thermodynamic theory for material chains made up of nanoscopic subunits with symbolic meaning in the presence of memory. This framework is based on the characterization of single sequences of symbols constructed under a protocol and is used to derive the behavior of ensembles of sequences similarly constructed...
November 28, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29173055/an-aristotelian-view-of-therapists-practice-in-multifamily-therapy-for-young-adults-with-severe-eating-disorders
#7
Berit Støre Brinchmann, Cathrine Moe, Mildrid Elisabeth Valvik, Steven Balmbra, Siri Lyngmo, Tove Skarbø
BACKGROUND: Eating disorders are serious conditions which also impact the families of adult patients. There are few qualitative studies of multifamily therapy with adults with severe eating disorders and none concerning the practice of therapists in multifamily therapy. OBJECTIVES: The aim of the study is to explore therapists' practice in multifamily therapy. Research design and participants: A grounded theory approach was chosen. Data were collected through participant observation in two multifamily therapy groups and qualitative interviews with the therapists in those groups...
January 1, 2017: Nursing Ethics
https://www.readbyqxmd.com/read/29152633/conformational-collapse-of-spherical-poly-n-isopropylacrylamide-brushes-under-the-constraint-of-bound-micelles
#8
Peng-Wei Zhu, Luguang Chen
In this paper, we investigate the micelle (charge)-constrained collapse of a spherical poly(N-isopropylacrylamide) (PNIPAM) brush. The system is an example of the transition of a short-length neutral polymer from a stretched state to a folded state under the constraint of long-range electrostatic repulsion. The collapsed state is described as an anisotropic globule comprising a cascade of rod-like or hairpin bundles. A critical aggregation number of bound micelles is obtained to distinguish the charge-induced deformation of the globule, which provides a guideline to characterize globule dimensions under different strengths of electrostatic interaction...
November 20, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29138311/intrusion-and-extrusion-of-water-in-hydrophobic-nanopores
#9
Antonio Tinti, Alberto Giacomello, Yaroslav Grosu, Carlo Massimo Casciola
Heterogeneous systems composed of hydrophobic nanoporous materials and water are capable, depending on their characteristics, of efficiently dissipating (dampers) or storing ("molecular springs") energy. However, it is difficult to predict their properties based on macroscopic theories-classical capillarity for intrusion and classical nucleation theory (CNT) for extrusion-because of the peculiar behavior of water in extreme confinement. Here we use advanced molecular dynamics techniques to shed light on these nonclassical effects, which are often difficult to investigate directly via experiments, owing to the reduced dimensions of the pores...
November 14, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29120216/bridging-the-gap-learning-of-acoustic-nonadjacent-dependencies-by-a-songbird
#10
Jiani Chen, Carel Ten Cate
Many animal species can detect dependencies between adjacent visual or auditory items in a string. Compared with adjacent dependencies, detecting nonadjacent dependencies, as present in linguistic constructions, is more challenging as this requires detecting a relation between items irrespective of the number and nature of the intervening items. There is limited evidence that nonhuman animals can detect such dependencies. An animal group in which such abilities might be expected is songbirds, which have learned songs consisting of a series of vocal elements given in specific sequences...
July 2017: Journal of Experimental Psychology. Animal Learning and Cognition
https://www.readbyqxmd.com/read/29118667/twistor-theory-at-fifty-from-contour-integrals-to-twistor-strings
#11
REVIEW
Michael Atiyah, Maciej Dunajski, Lionel J Mason
We review aspects of twistor theory, its aims and achievements spanning the last five decades. In the twistor approach, space-time is secondary with events being derived objects that correspond to compact holomorphic curves in a complex threefold-the twistor space. After giving an elementary construction of this space, we demonstrate how solutions to linear and nonlinear equations of mathematical physics-anti-self-duality equations on Yang-Mills or conformal curvature-can be encoded into twistor cohomology...
October 2017: Proceedings. Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/29110287/a-novel-hypergraph-based-genetic-algorithm-hgga-built-on-unimodular-and-anti-homomorphism-properties-for-dna-sequencing-by-hybridization
#12
V Swaminathan, Gangothri Rajaram, V Abhishek, Boosi Shashank Reddy, K Kannan
The sequencing by hybridization (SBH) of determining the order in which nucleotides should occur on a DNA string is still under discussion for enhancements on computational intelligence although the next generation of DNA sequencing has come into existence. In the last decade, many works related to graph theory-based DNA sequencing have been carried out in the literature. This paper proposes a method for SBH by integrating hypergraph with genetic algorithm (HGGA) for designing a novel analytic technique to obtain DNA sequence from its spectrum...
November 6, 2017: Interdisciplinary Sciences, Computational Life Sciences
https://www.readbyqxmd.com/read/29054292/addiction-a-dysregulation-of-satiety-and-inflammatory-processes
#13
Rivona Harricharan, Oualid Abboussi, William M U Daniels
Over the years, drug addiction has proven to be a perplexing conundrum for scientists. In attempts to decipher the components of the puzzle, multiple theories of addiction have been proposed. While these theories have assisted in providing essential fundamental information, current research recommends that a new theory needs to be presented taking into consideration the results of recent developments in the fields of neuroimmunology, genetics, and neuropsychiatry. After extensively examining the published literature, we propose in this review that neuroinflammation and hypothalamic functioning strongly underpin addictive behavior...
2017: Progress in Brain Research
https://www.readbyqxmd.com/read/29037663/unilateral-forelimb-sensorimotor-cortex-devascularization-disrupts-the-topographic-and-kinematic-characteristics-of-hand-movements-while-string-pulling-for-food-in-the-rat
#14
Ashley A Blackwell, William L Widick, Joseph L Cheatwood, Ian Q Whishaw, Douglas G Wallace
String-pulling by the rat is a bimanual act, in which an upright animal retrieves a piece of food attached to the end of the string by downward hand-over-hand movements. The present study compared the movements of string-pulling, using topographic and kinematic measures of hand movement, in control rats and rats with unilateral sensorimotor motor cortex lesion produced by removal of the pia matter. In the first week following devascularization, the rhythmicity and accuracy of string-pulling movements decomposed; however, thereafter the rhythm of bilateral alternation was restored...
October 14, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28983268/strong-generative-capacity-and-the-empirical-base-of-linguistic-theory
#15
Dennis Ott
This Perspective traces the evolution of certain central notions in the theory of Generative Grammar (GG). The founding documents of the field suggested a relation between the grammar, construed as recursively enumerating an infinite set of sentences, and the idealized native speaker that was essentially equivalent to the relation between a formal language (a set of well-formed formulas) and an automaton that recognizes strings as belonging to the language or not. But this early view was later abandoned, when the focus of the field shifted to the grammar's strong generative capacity as recursive generation of hierarchically structured objects as opposed to strings...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28957627/automated-transition-state-search-and-its-application-to-diverse-types-of-organic-reactions
#16
Leif D Jacobson, Art D Bochevarov, Mark A Watson, Thomas F Hughes, David Rinaldo, Stephan Ehrlich, Thomas B Steinbrecher, S Vaitheeswaran, Dean M Philipp, Mathew D Halls, Richard A Friesner
Transition state search is at the center of multiple types of computational chemical predictions related to mechanistic investigations, reactivity and regioselectivity predictions, and catalyst design. The process of finding transition states in practice is, however, a laborious multistep operation that requires significant user involvement. Here, we report a highly automated workflow designed to locate transition states for a given elementary reaction with minimal setup overhead. The only essential inputs required from the user are the structures of the separated reactants and products...
October 17, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28952773/direct-observation-of-dynamical-quantum-phase-transitions-in-an-interacting-many-body-system
#17
P Jurcevic, H Shen, P Hauke, C Maier, T Brydges, C Hempel, B P Lanyon, M Heyl, R Blatt, C F Roos
The theory of phase transitions represents a central concept for the characterization of equilibrium matter. In this work we study experimentally an extension of this theory to the nonequilibrium dynamical regime termed dynamical quantum phase transitions (DQPTs). We investigate and measure DQPTs in a string of ions simulating interacting transverse-field Ising models. During the nonequilibrium dynamics induced by a quantum quench we show for strings of up to 10 ions the direct detection of DQPTs by revealing nonanalytic behavior in time...
August 25, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28949566/confinement-in-the-bulk-deconfinement-on-the-wall-infrared-equivalence-between-compactified-qcd-and-quantum-magnets
#18
Tin Sulejmanpasic, Hui Shao, Anders W Sandvik, Mithat Ünsal
In a spontaneously dimerized quantum antiferromagnet, spin-1/2 excitations (spinons) are confined in pairs by strings akin to those confining quarks in non-Abelian gauge theories. The system has multiple degenerate ground states (vacua) and domain walls between regions of different vacua. For two vacua, we demonstrate that spinons on a domain wall are liberated, in a mechanism strikingly similar to domain-wall deconfinement of quarks in variants of quantum chromodynamics. This observation not only establishes a novel phenomenon in quantum magnetism, but also provides a new direct link between particle physics and condensed-matter physics...
September 1, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28949212/gauss-bonnet-supergravity-in-six-dimensions
#19
Joseph Novak, Mehmet Ozkan, Yi Pang, Gabriele Tartaglino-Mazzucchelli
The supersymmetrization of curvature squared terms is important in the study of the low-energy limit of compactified superstrings where a distinguished role is played by the Gauss-Bonnet combination, which is ghost-free. In this Letter, we construct its off-shell N=(1,0) supersymmetrization in six dimensions for the first time. By studying this invariant together with the supersymmetric Einstein-Hilbert term, we confirm and extend known results of the α^{'}-corrected string theory compactified to six dimensions...
September 15, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28943783/light-and-compressed-gluinos-at-the-lhc-via-string-theory
#20
S S AbdusSalam
In this article, we show that making global fits of string theory model parameters to data is an interesting mechanism for probing, mapping and forecasting connections of the theory to real world physics. We considered a large volume scenario (LVS) with D3-brane matter fields and supersymmetry breaking. A global fit of the parameters to low-energy data shows that the set of LVS models are associated with light gluinos which are quasi-degenerate with the neutralinos and charginos they can promptly decay into, and thus they are possibly hidden to current LHC gluino search strategies...
2017: European Physical Journal. C, Particles and Fields
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