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Public attitudes pharmacogenomics knowledge

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https://www.readbyqxmd.com/read/24167008/stakeholder-views-on-pharmacogenomic-testing
#1
REVIEW
Haridarshan N Patel, Iulia D Ursan, Patrick M Zueger, Larisa H Cavallari, A Simon Pickard
Pharmacogenomics has an important role in the evolution of personalized medicine, and its widespread uptake may ultimately depend on the interests and perspectives of key players in health care. Our aim was to summarize studies on stakeholder perspectives and attitudes toward pharmacogenomic testing. Thus, we conducted a review of original research studies that reported stakeholder views on pharmacogenomic testing using a structured approach in PubMed, International Pharmaceutical Abstracts, Cumulative Index to Nursing and Allied Health Literature, and EMBASE...
February 2014: Pharmacotherapy
https://www.readbyqxmd.com/read/23893861/pharmacogenetic-testing-in-the-face-of-unclear-clinical-efficacy-lessons-from-cytochrome-p450-2d6-for-tamoxifen
#2
RANDOMIZED CONTROLLED TRIAL
Jeffrey Peppercorn, Erika Hamilton, Paul Kelly Marcom, Laura Beskow, Gary H Lyman
BACKGROUND: This study evaluated self-reported knowledge, practice, and attitudes toward commercially available cytochrome P450 2D6 (CYP2D6) pharmacogenomic testing for patients on tamoxifen for breast cancer (CYPT) among US oncologists while evidence for the use of the test was evolving. METHODS: A self-administered survey of medical oncology breast cancer specialists at National Comprehensive Cancer Network (NCCNO) centers and a random sample of community-based oncologists (CBOs) was undertaken...
October 15, 2013: Cancer
https://www.readbyqxmd.com/read/22272758/ethics-and-neuropsychiatric-genetics-a-review-of-major-issues
#3
REVIEW
Steven K Hoge, Paul S Appelbaum
Advances in neuropsychiatric genetics hold great hopes for improved prevention, diagnosis and treatment. However, the power of genetic testing to identify individuals at increased risk for disorders and to convey information about relatives creates a set of complex ethical issues. Public attitudes are inevitably affected by the shadow of eugenics, with its history of distorting scientific findings to serve socio-political ends. Nonetheless, the growing availability of genetic tests means that more patients will seek genetic information and physicians must manage the process of informed consent to allow meaningful decisions...
November 2012: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/19629751/public-involvement-in-pharmacogenomics-research-a-national-survey-on-public-attitudes-towards-pharmacogenomics-research-and-the-willingness-to-donate-dna-samples-to-a-dna-bank-in-japan
#4
Eriko Kobayashi, Nobunori Satoh
To assess the attitudes of the Japanese general public towards pharmacogenomics research and a DNA bank for identifying genomic markers associated with ADRs and their willingness to donate DNA samples, we conducted a national survey for 1,103 Japanese adults from the general public, not a patient population. The response rate was 36.8%. The majority of the respondents showed a positive attitude towards pharmacogenomics research (81.0%) and a DNA bank (70.4%). Considering fictitious clinical situations such as taking medications and experiencing ADRs, the willingness to donate DNA samples when experiencing ADRs (61...
November 2009: Cell and Tissue Banking
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