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https://www.readbyqxmd.com/read/27919572/non-fucosylated-cb-cd34-cells-represent-a-good-target-for-enforced-fucosylation-to-improve-engraftment-following-cord-blood-transplantation
#1
Simon N Robinson, Michael W Thomas, Paul J Simmons, Junjun Lu, Hong Yang, Jeannie A Javni, Elizabeth J Shpall, Patrick A Zweidler-Mckay
BACKGROUND AIMS: Despite ethnic diversity and ready availability of cryopreserved, human leukocyte antigen-typed cord blood (CB), delayed engraftment remains a significant hurdle to successful CB transplantation. Suboptimal homing of CB hematopoietic stem and progenitor cells (HSPCs) to the hematopoietic microenvironment (HM) is thought to be responsible and due to low levels of HSPC fucosylation. Fucosylation (decoration with sialyl-Lewis(X)) may improve HSPC homing to HM by increasing the strength of HSPC/E-selectin interactions, where E-selectin is constitutively expressed by HM microvasculature...
December 2, 2016: Cytotherapy
https://www.readbyqxmd.com/read/27905014/sexual-venue-choice-and-sexual-risk-taking-among-substance-using-men-who-have-sex-with-men
#2
Joshua A Rusow, Jesse B Fletcher, Cathy J Reback
Commercial sex venues (CSVs) and public sex environments (PSEs) offer men who have sex with men (MSM) sexual privacy and anonymity. Sociodemographic characteristics (e.g., race/ethnicity, sexual identity, age, HIV status) are correlated with individuals' choice of sexual venue, potentially suggesting environmental associations with both sociodemographics and sexual risk. From March 2005 through March 2012, 1298 substance-using MSM provided information on their most recent sexual encounter; iterative logit models estimated associations between sociodemographics and sexual venue, and/or whether sexual venue was associated with sexual risk-taking while controlling for sociodemographics...
November 30, 2016: AIDS and Behavior
https://www.readbyqxmd.com/read/27893228/ethnic-identity-factor-structure-and-measurement-invariance-across-ethnic-groups
#3
Jennifer Feitosa, Christina N Lacerenza, Dana L Joseph, Eduardo Salas
Considering a historically diversified (and growing) population in the United States, one's ethnic identification is often an important psychological-as well as social and political-construct because it can serve as a hindrance to interpersonal interaction. Despite the importance of ethnic identity in psychological research, the most widely developed ethnic identity measurement tool, the Multigroup Ethnic Identity Measure (MEIM; Phinney, 1992), lacks consensus regarding its psychometric properties. The purpose of this article is to identify the factor structure of this measure and identify whether it exhibits measurement equivalence/invariance (ME/I) across ethnicities...
November 28, 2016: Psychological Assessment
https://www.readbyqxmd.com/read/27892844/identification-of-b-cell-epitope-of-leishmania-donovani-and-its-application-in-diagnosis-of-visceral-leishmaniasis
#4
Fauzia Jamal, Manas Ranjan Dikhit, Manish K Singh, Pushkar Shivam, Sarita Kumari, Pushpanjali, Amit K Dubey, Prakash Kumar, Shyam Narayan, Anil K Gupta, Krishna Pandey, V N R Das, Sanjiva Bimal, Pradeep Das, Shubhankar K Singh
Diagnosis of visceral leishmaniasis (VL) is often hindered by cross-reactions with antigens from other related parasite infections. This study aimed to develop an immunochromatographic test (ICT) which can detect the antigen present in circulating immune complexes (CICs) of VL patients using B cell epitope-specific antibodies. MS analysis of six immunoreactive 2DE spots revealed two epitopes i.e RFFVQGDGIGQHSLQEALERR (P1) and RRVAVLVLLDRL (P2) (From a hypothetical protein [Acc No: XP_003861458.1]). The epitope conservancy analysis suggested that the linear epitope (P1P2) is 97% to 100% conserved among Leishmania species and diverged from Homo sapiens (61% query coverage and 80% identity)...
November 28, 2016: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/27892696/looking-like-a-smoker-a-smokescreen-to-racism-m%C3%A4-ori-perceived-appearance-linked-to-smoking-status
#5
E Muriwai, C A Houkamau, C G Sibley
OBJECTIVES: Māori, the indigenous peoples of Aotearoa (New Zealand), continue to exhibit the highest rate of smoking of any ethnic group in the nation. Clarifying the present day factors which perpetuate Māori smoking has become matter of some urgency. DESIGN: We investigate links between subjective elements of Māori identity, demographic factors and perceived discrimination with smoking status in a national probability sample of self-identified Māori (N = 667)...
November 28, 2016: Ethnicity & Health
https://www.readbyqxmd.com/read/27891059/ethnic-identity-attachment-and-motivation-for-weight-loss-and-exercise-among-rural-overweight-african-american-women
#6
K Bryant Smalley, Jacob C Warren, Sydney McClendon, Wilburn Peacock, Marisol Caro
Rural and minority women are disproportionately impacted by the obesity epidemic; however, little research has studied the intersection of these disparity groups. The purpose of this study was to examine the influence of racial identity on motivation for weight loss and exercise among rural, African-American women with an obesity-linked chronic disease. A total of 154 African-American women were recruited from the patient population of a Federally Qualified Health Center in the rural South to complete a questionnaire battery including the Multigroup Ethnic Identity Measure and separate assessments of motivation for weight loss and exercise...
2016: Clinical Medicine Insights. Women's Health
https://www.readbyqxmd.com/read/27884128/a-randomised-controlled-demonstration-trial-of-multifaceted-nutritional-intervention-and-or-probiotics-the-healthy-mums-and-babies-humba-trial
#7
Karaponi Okesene-Gafa, Minglan Li, Rennae S Taylor, John M D Thompson, Caroline A Crowther, Christopher J D McKinlay, Lesley M E McCowan
BACKGROUND: Maternal obesity is associated with adverse pregnancy outcomes and has lifelong negative implications for offspring health. The Institute of Medicine recommends limited gestational weight gain (GWG) in obese women for optimal maternal and infant outcomes. However, there is a gap regarding an effective and sustainable intervention strategy to achieve this goal. The aim of the healthy mums and babies (HUMBA) demonstration trial is to assess whether a multifaceted nutritional intervention and/or an oral probiotic treatment in obese pregnant women can reduce excessive GWG and optimise pregnancy outcomes...
November 24, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27878538/enhancing-and-expanding-intersectional-research-for-climate-change-adaptation-in-agrarian-settings
#8
Mary Thompson-Hall, Edward R Carr, Unai Pascual
Most current approaches focused on vulnerability, resilience, and adaptation to climate change frame gender and its influence in a manner out-of-step with contemporary academic and international development research. The tendency to rely on analyses of the sex-disaggregated gender categories of 'men' and 'women' as sole or principal divisions explaining the abilities of different people within a group to adapt to climate change, illustrates this problem. This framing of gender persists in spite of established bodies of knowledge that show how roles and responsibilities that influence a person´s ability to deal with climate-induced and other stressors emerge at the intersection of diverse identity categories, including but not limited to gender, age, seniority, ethnicity, marital status, and livelihoods...
December 2016: Ambio
https://www.readbyqxmd.com/read/27875830/stigma-in-an-aging-context
#9
Charles A Emlet
Both the Joint United Nations Program on HIV/AIDS and the US National HIV/AIDS Strategy identify HIV stigma as a barrier to care, a barrier to service access, and deleterious to personal and social well-being. This chapter discusses the topic of HIV stigma from a conceptual basis, including the mechanisms of prejudice and discrimination, and defining anticipated, enacted, and internalized stigma. Stigma is then placed in a historical context of HIV and AIDS, and events exacerbating HIV stigma are discussed...
2017: Interdisciplinary Topics in Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27862186/a-systematic-review-and-qualitative-synthesis-of-adolescents-views-of-sexual-readiness
#10
REVIEW
Michelle Templeton, Maria Lohan, Carmel Kelly, Laura Lundy
AIM: The aim of this study was to synthesize the qualitative evidence investigating adolescents' views on heterosexual readiness. BACKGROUND: Adolescents' understandings of sexual readiness are often missing in research and debates on sexual health and related concepts like sexual consent. Research to date has predominantly focussed on age and socio-cultural predictors of sexual debut, thus failing to explain how adolescents themselves conceptualize their readiness for heterosexual relations...
November 11, 2016: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/27852712/perceived-barriers-to-accessing-mental-health-services-among-black-and-minority-ethnic-bme-communities-a-qualitative-study-in-southeast-england
#11
Anjum Memon, Katie Taylor, Lisa M Mohebati, Josefin Sundin, Max Cooper, Thomas Scanlon, Richard de Visser
OBJECTIVE: In most developed countries, substantial disparities exist in access to mental health services for black and minority ethnic (BME) populations. We sought to determine perceived barriers to accessing mental health services among people from these backgrounds to inform the development of effective and culturally acceptable services to improve equity in healthcare. DESIGN AND SETTING: Qualitative study in Southeast England. PARTICIPANTS: 26 adults from BME backgrounds (13 men, 13 women; aged >18 years) were recruited to 2 focus groups...
November 16, 2016: BMJ Open
https://www.readbyqxmd.com/read/27846733/ethnicity-work-related-stress-and-subjective-reports-of-health-by-migrant-workers-a-multi-dimensional-model
#12
Roberto Capasso, Maria Clelia Zurlo, Andrew P Smith
OBJECTIVES: This study integrates different aspects of ethnicity and work-related stress dimensions (based on the Demands-Resources-Individual-Effects model, DRIVE [Mark, G. M., and A. P. Smith. 2008. "Stress Models: A Review and Suggested New Direction." In Occupational Health Psychology, edited by J. Houdmont and S. Leka, 111-144. Nottingham: Nottingham University Press]) and aims to test a multi-dimensional model that combines individual differences, ethnicity dimensions, work characteristics, and perceived job satisfaction/stress as independent variables in the prediction of subjectives reports of health by workers differing in ethnicity...
November 16, 2016: Ethnicity & Health
https://www.readbyqxmd.com/read/27845947/preventing-suicide-in-indigenous-communities
#13
Simon Hatcher, Allison Crawford, Nicole Coupe
PURPOSE OF REVIEW: To provide an update on recent studies on suicide prevention in indigenous populations with a focus on recently colonised indigenous peoples in Canada, the United States, Australia and New Zealand. RECENT FINDINGS: There have been several recent reviews on suicide prevention in indigenous populations with high suicide rates. However most of them describe the problem and there is little new that is available on effective interventions. One randomized controlled trial of a package of measures focusing on cultural identity in Maori who had recently self-harmed compared to usual care found little effect on suicidal behavior but it did significantly reduce presentations to hospital for any reason after one year...
January 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/27845525/feminist-identity-among-women-and-men-from-four-ethnic-groups
#14
Rachael D Robnett, Kristin J Anderson
OBJECTIVE: Multiracial feminist theory proposes that the meaning of feminism and the pathways to feminist identity may differ on the basis of cross-cutting social categories such as ethnicity and gender. However, there is currently little research that has included systematic examination of feminist identity among women and men from diverse ethnic backgrounds. METHOD: We examined feminist orientations among 1,140 undergraduates (70% women) at a Hispanic-Serving Institution who identified as African American, Asian American, European American, or Latina/o...
June 16, 2016: Cultural Diversity & Ethnic Minority Psychology
https://www.readbyqxmd.com/read/27833667/connection-between-depression-and-inability-to-fill-prescriptions-in-rural-fqhc-patients-with-chronic-disease
#15
K Bryant Smalley, Jacob C Warren, K Nikki Barefoot
The purpose of this paper was to (1) examine the rates of elevated depression symptoms among a sample of rural Federally Qualified Health Center (FQHC) patients with chronic disease and (2) determine if an inability to afford general prescription medications within the past 12 months is a significant predictor of depression symptoms among these patients. These data came from Project EDUCATE, an ongoing five-year study designed to be a large-scale, multifocal examination of the needs and experiences of rural FQHC patients with hypertension and/or diabetes...
April 2016: Rural Mental Health
https://www.readbyqxmd.com/read/27830403/examining-the-protective-effect-of-ethnic-identity-on-drug-attitudes-and-use-among-a-diverse-youth-population
#16
Tamika C B Zapolski, Sycarah Fisher, Devin E Banks, Devon J Hensel, Jessica Barnes-Najor
Ethnic identity is an important buffer against drug use among minority youth. However, limited work has examined pathways through which ethnic identity mitigates risk. School-aged youth (N = 34,708; 52 % female) of diverse backgrounds (i.e., African American (n = 5333), Asian (n = 392), Hispanic (n = 662), Multiracial (n = 2129), Native American (n = 474), and White (n = 25718) in grades 4-12 provided data on ethnic identity, drug attitudes, and drug use. After controlling for gender and grade, higher ethnic identity was associated with lower past month drug use for African American, Hispanic, and Multiracial youth...
November 9, 2016: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/27825351/determining-the-spatial-heterogeneity-underlying-racial-and-ethnic-differences-in-timely-mammography-screening
#17
Joseph Gibbons, Melody K Schiaffino
BACKGROUND: The leading cause of cancer death for women worldwide continues to be breast cancer. Early detection through timely mammography has been recognized to increase the probability of survival. While mammography rates have risen for many women in recent years, disparities in screening along racial/ethnic lines persist across nations. In this paper, we argue that the role of local context, as identified through spatial heterogeneity, is an unexplored dynamic which explains some of the gaps in mammography utilization by race/ethnicity...
November 8, 2016: International Journal of Health Geographics
https://www.readbyqxmd.com/read/27816231/distribution-of-the-fmr1-gene-in-females-by-race-ethnicity-women-with-diminished-ovarian-reserve-versus-women-with-normal-fertility-swan-study
#18
Lisa M Pastore, Steven L Young, Ani Manichaikul, Valerie L Baker, Xin Q Wang, Joel S Finkelstein
OBJECTIVE: To study whether reported, but inconsistent, associations between the FMR1 CGG repeat lengths in the intermediate, high normal, or low normal range differentiate women diagnosed with diminished ovarian reserve (DOR) from population controls and whether associations vary by race/ethnic group. DESIGN: Case-control study. SETTING: Academic and private fertility clinics. PATIENT(S): DOR cases (n = 129; 95 Whites, 22 Asian, 12 other) from five U...
November 2, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27815326/negative-responses-to-disclosure-of-sexual-victimization-and-victims-symptoms-of-ptsd-and-depression-the-protective-role-of-ethnic-identity
#19
Valentina Nikulina, Adrian Bautista, Elissa J Brown
College-aged women experience high rates of sexual victimization. Their postassault symptoms are associated with the types of responses they receive from the people to whom they disclose these experiences. Negative responses are pervasive and associated with poorer outcomes. The current study examined whether a strong sense of ethnic identity and comfort with the mainstream culture moderate the association between negative responses to the first disclosure of sexual victimization and symptoms of posttraumatic stress disorder (PTSD) and depression...
November 3, 2016: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/27813363/illness-perceptions-predict-mortality-in-patients-with-gout-a-prospective-observational-study
#20
Anna Serlachius, Greg Gamble, Meaghan House, Zoe L Vincent, Julie Knight, Anne Horne, William J Taylor, Keith J Petrie, Nicola Dalbeth
OBJECTIVE: To examine whether illness perceptions independently predict mortality in early-onset gout. METHODS: Between December 2006-January 2014, a total of 295 participants with early-onset gout (<10 years) were recruited in Auckland and Wellington, New Zealand. The participants were followed up until February 2015 and mortality information was collected. Participants with complete data were included in the current study (n=242). Cox proportional hazards models were used to examine the association between illness perceptions and risk of mortality, after adjusting for covariates associated with disease severity and mortality in gout...
November 3, 2016: Arthritis Care & Research
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