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https://www.readbyqxmd.com/read/28822742/strategy-set-shifting-and-response-inhibition-in-adult-rats-exposed-to-an-environmental-polychlorinated-biphenyl-mixture-during-adolescence
#1
Supida Monaikul, Paul Eubig, Stan Floresco, Susan Schantz
Converging evidence from studies with animal models and humans suggests that early developmental exposure to polychlorinated biphenyls (PCBs) leads to deficits in cognitive flexibility and inhibitory control. These processes are mediated to a large extent by the prefrontal cortex, thus we examined the effects of PCB exposure during adolescence-a period of robust prefrontal cortical development-on both processes. Specifically, we used operant set-shifting and differential reinforcement of low rates of responding (DRL) tasks to assess cognitive flexibility and response inhibition, respectively...
August 16, 2017: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/28822682/a-systematic-review-of-digital-interventions-for-improving-the-diet-and-physical-activity-behaviors-of-adolescents
#2
REVIEW
Taylor Rose, Mary Barker, Chandni Maria Jacob, Leanne Morrison, Wendy Lawrence, Sofia Strömmer, Christina Vogel, Kathryn Woods-Townsend, David Farrell, Hazel Inskip, Janis Baird
Many adolescents have poor diet and physical activity behaviors, which can lead to the development of noncommunicable diseases in later life. Digital platforms offer inexpensive means of delivering health interventions, but little is known about their effectiveness. This systematic review was conducted to synthesize evidence on the effectiveness of digital interventions to improve diet quality and increase physical activity in adolescents, to effective intervention components and to assess the cost-effectiveness of these interventions...
August 16, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28822477/spinal-manipulative-therapy-for-adolescent-idiopathic-scoliosis-a-systematic-review
#3
Jean Théroux, Norman Stomski, Christine Dominique Losco, Christelle Khadra, Hubert Labelle, Sylvie Le May
OBJECTIVE: The purpose of this study was to perform a systematic review of clinical trials of spinal manipulative therapy for adolescent idiopathic scoliosis. METHODS: Search strategies were developed for PubMed, CINHAL, and CENTRAL databases. Studies were included through June 2016 if they were prospective trials that evaluated spinal manipulative therapy (eg, chiropractic, osteopathic, physical therapy) for adolescent idiopathic scoliosis. Data were extracted and assessed by 2 independent reviewers...
July 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28821657/fronto-parietal-structural-connectivity-in-childhood-predicts-development-of-functional-connectivity-and-reasoning-ability-a-large-scale-longitudinal-investigation
#4
Carter Wendelken, Emilio Ferrer, Simona Ghetti, Stephen Bailey, Laurie Cutting, Silvia A Bunge
Prior research points to a positive concurrent relationship between reasoning ability and both fronto-parietal structural connectivity, as measured by diffusion tensor imaging (e.g. Tamnes et al., 2010), and fronto-parietal functional connectivity, as measured by fMRI (e.g. Cocchi et al., 2014). Further, recent research demonstrates a link between reasoning ability and functional connectivity of two brain regions in particular: rostrolateral prefrontal cortex (RLPFC) and the inferior parietal lobe (IPL) (Wendelken et al...
August 7, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28821442/time-in-brace-where-are-the-limits-and-how-can-we-improve-compliance-and-reduce-negative-psychosocial-impact-in-scoliosis-patients-a-retrospective-analysis
#5
Markus Rafael Konieczny, Paula Hieronymus, Rüdiger Krauspe
Background Brace treatment for adolescent idiopathic scoliosis (AIS) is generally prescribed for 18 - 23 hours per day, but the minimal time of brace wear per day to stop progression of AIS is still unclear. Compliance of AIS patients with brace treatment is reported to be between 27% and 47% of the prescribed time, especially brace wear at school is often described as embarrassing by the adolescent patients. It has been reported that a higher rate of compliance leads to a significantly lower rate of curve progression...
August 15, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28821292/the-relationship-between-obesity-and-body-compositions-with-respect-to-the-timing-of-puberty-in-chongqing-adolescents-a-cross-sectional-study
#6
Fang He, Peiyu Guan, Qin Liu, Donna Crabtree, Linli Peng, Hong Wang
BACKGROUND: It is well known that excess adiposity during childhood may influence pubertal development. However, the extent to which body compositions vary in throughout puberty in boys and girls is currently unknown. The aim of this study was to investigate whether obesity and body compositions correlate with the timing of puberty in boys and girls. METHODS: By random cluster sampling, our study analyzed data from 1472 students (690 girls, 782 boys) aged 6-17 years from two schools in the Chongqing area...
August 18, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28821214/the-construction-and-psychometric-properties-of-the-questionnaire-for-online-sexual-solicitation-and-interaction-of-minors-with-adults
#7
Manuel Gámez-Guadix, Patricia De Santisteban, Miguel Ángel Alcazar
The objective of this study was to develop a questionnaire to assess the online sexual solicitation and interactions of minors with adults in order to document the extent of this problem. The questionnaire was constructed in four phases: (a) a review of the previous literature; (b) interviews with convicted online child-sex offenders; (c) a review of the questionnaire items by experts; and (d) a pilot study of the questionnaire administered to adolescents. The validation sample consisted of 2,731 minors (12-15 years old, 50...
August 1, 2017: Sexual Abuse: a Journal of Research and Treatment
https://www.readbyqxmd.com/read/28820789/suicide-resilience-and-connectedness-across-the-lifespan-lessons-from-american-indian-and-alaska-native-elders
#8
Satya Rao, Dylan Pell, Elizabeth S England-Kennedy
Rates of suicide and associated costs are high and increasing in the United States. From 1999 through 2014, the age-adjusted suicide rate increased 24%, with the pace of increase being greater since 2006. American Indian and Alaska Native persons have significantly lower rates of suicides than other ethnic groups as elders despite experiencing some of the highest rates during adolescence. This article examines literature pertaining to suicide rates in American Indian and Alaska Native communities and proposes a framework for understanding their lower rates of suicide as elders...
October 2017: Family & Community Health
https://www.readbyqxmd.com/read/28820619/associations-between-anxious-and-depressive-symptoms-and-the-recognition-of-vocal-socioemotional-expressions-in-youth
#9
Michele Morningstar, Melanie A Dirks, Brent I Rappaport, Daniel S Pine, Eric E Nelson
The current study examined the associations between internalizing symptoms and adolescents' recognition of vocal socioemotional expressions produced by youth. Fifty-seven youth (8-17 years old, M = 12.62, SD = 2.66; 29 anxious, 28 nonanxious; 32 female, 25 male) were asked to identify the intended expression in auditory recordings of youth's portrayals of basic emotions and social attitudes. Recognition accuracy increased with age, suggesting that the ability to recognize vocal affect continues to develop into adolescence...
August 18, 2017: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/28819992/insulin-delivery-and-nocturnal-glucose-control-in-children-and-adolescents-with-type-1-diabetes
#10
Martin Tauschmann, Roman Hovorka
Nocturnal glucose control remains challenging in children and adolescents with type 1 diabetes due to highly variable overnight insulin requirements. The issue may be addressed by glucose responsive insulin delivery based on real-time continuous glucose measurements. Areas covered: This review outlines recent developments of glucose responsive insulin delivery systems from a paediatric perspective. We cover threshold-based suspend application, predictive low glucose suspend, and more advanced single hormone and dual-hormone closed-loop systems...
August 18, 2017: Expert Opinion on Drug Delivery
https://www.readbyqxmd.com/read/28819947/secondary-dysmenorrhea-due-to-a-rudimentary-non-communicating-functional-uterine-horn
#11
Ewa Woźniakowska, Anna Stępniak, Piotr Czuczwar, Paweł Milart, Tomasz Paszkowski
Unicornuate uterus with a rudimentary horn is a rare congenital Müllerian anomaly, which may lead to many obstetrical and gynaecological complications. This pathology occurs in approximately 1/100 000 women. A rudimentary horn forms due to insufficient development of the Müllerian duct. The diagnosis of this anomaly is usually delayed, as it remains asymptomatic until adolescence and its main symptom is dysmenorrhea.
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28819911/neighborhood-family-and-peer-factors-associated-with-early-adolescent-smoking-and-alcohol-use
#12
Christopher Cambron, Rick Kosterman, Richard F Catalano, Katarina Guttmannova, J David Hawkins
There is broad agreement that neighborhood contexts are important for adolescent development, but there is less consensus about their association with adolescent smoking and alcohol use. Few studies have examined associations between neighborhood socioeconomic contexts and smoking and alcohol use while also accounting for differences in family and peer risk factors for substance use. Data drawn from the Seattle Social Development Project (N = 808), a gender-balanced (female = 49%), multiethnic, theory-driven longitudinal study originating in Seattle, WA, were used to estimate trajectories of smoking and alcohol use from 5th to 9th grade...
August 18, 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/28819639/antioxidant-treatment-in-male-mice-prevents-mitochondrial-and-synaptic-changes-in-an-nmda-receptor-dysfunction-model-of-schizophrenia
#13
Aarron Phensy, Christopher Driskill, Karen Lindquist, Lan Guo, Vivek Jeevakumar, Bryan Fowler, Heng Du, Sven Kroener
Glutamate theories of schizophrenia suggest that the disease is associated with a loss of NMDA receptors, specifically on GABAergic parvalbumin-expressing interneurons (PVIs), leading to changes in the excitation-inhibition balance in the prefrontal cortex (PFC). Oxidative stress contributes to the loss of PVI and the development of schizophrenia. Here, we investigated whether the glutathione precursor N-acetyl cysteine (NAC) can prevent changes in synaptic transmission at pyramidal cells and PVIs that result from developmental NMDAR blockade and how these changes are related to mitochondrial dysfunction in the PFCs of mice...
July 2017: ENeuro
https://www.readbyqxmd.com/read/28819372/survival-changes-in-patients-with-synovial-sarcoma-1983-2012
#14
Shuncong Wang, Rongfeng Song, Tiantian Sun, Bingzong Hou, Guobin Hong, Saradhi Mallampati, Hongliu Sun, Xiuling Zhou, Cuiling Zhou, Hongyu Zhang, Zhibin Cheng, Jie Li, Haiqing Ma, Huanhuan Sun
Background: Synovial sarcoma (SyS) is a rare malignancy that typically invades the extremities and occurs predominantly in adolescents. Studies on incidence and survival in SyS that were based on a large population had not been reported yet. Methods: To evaluate changes in incidence and survival in SyS over three decades, we accessed data on SyS cases in each decade between 1983 and 2012 (1983-1992, 1993-2002, and 2003-2012) from the Surveillance, Epidemiology, and End Results (SEER) database. The survival difference between decades, age groups, sexes, race, pathologic types, sites, stages and socioeconomic status (SES) over three decades were accessed by comparing Kaplan-Meier curves...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28819107/medial-prefrontal-cortical-thinning-mediates-shifts-in-other-regarding-preferences-during-adolescence
#15
Sunhae Sul, Berna Güroğlu, Eveline A Crone, Luke J Chang
Adolescence is a time of significant cortical changes in the 'social brain', a set of brain regions involved in sophisticated social inference. However, there is limited evidence linking the structural changes in social brain to development of social behavior. The present study investigated how cortical development of the social brain relates to other-regarding behavior, in the context of fairness concerns. Participants aged between 9 to 23 years old responded to multiple rounds of ultimatum game proposals...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28818842/what-s-new-in-paediatric-hypertension
#16
REVIEW
Rowena Lalji, Kjell Tullus
Paediatric hypertension predisposes to hypertension and cardiovascular disease in adult life. Despite clear guidelines, there remains a lack of screening. Diagnosis remains challenging given the high rate of false-positive high blood pressure (BP) readings at a single visit; thus, multiple visits are required to confirm the diagnosis. Depending on the normative data sets used, hypertension in overweight and obese children can be underestimated by up to 20%. Specific BP targets are required for subgroups such as adolescents, children with chronic kidney disease (CKD) and type 1 diabetes...
August 17, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28818770/hereditary-multiple-exostoses-as-a-novel-cause-of-bilateral-popliteal-artery-aneurysms-in-the-elderly
#17
Eliza J Ferrari, Rory K Crotty, Katharina Eikermann-Haerter, James R Stone
Hereditary multiple exostoses (HME) is a genetic condition characterized by the development of multiple osteochondromas during childhood and adolescence. On rare occasions, these bony tumors can be associated with vascular injury, most commonly involving the popliteal artery. Such patients typically present with vascular complications in adolescence and young adulthood. We report an autopsy study of an elderly man who presented with bilateral popliteal artery pseudoaneurysms in the setting of HME at age 81...
July 8, 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/28818707/a-biomarker-of-anxiety-in-children-and-adolescents-a-review-focusing-on-the-error-related-negativity-ern-and-anxiety-across-development
#18
REVIEW
Alexandria Meyer
BACKGROUND: Anxiety disorders are the most common form of psychopathology and often begin early in development. Therefore, there is interest in identifying neural biomarkers that characterize pathways leading to anxiety disorders early in the course of development. A substantial amount of work focuses on the error-related negativity (ERN) as a biomarker of anxiety. While two previous reviews have focused on the relationship of the ERN and anxiety in adults, no previous review has focused on this issue in children and adolescents...
August 8, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/28818704/orphan-drug-regulation-a-missed-opportunity-for-children-and-adolescents-with-cancer
#19
Gilles Vassal, Pam Kearns, Patricia Blanc, Nicole Scobie, Delphine Heenen, Andy Pearson
BACKGROUND: Oncology represents a major sector in the field of orphan drug development in Europe. The objective was to evaluate whether children and adolescents with cancer benefited from the Orphan Drug Regulation. METHODS: Data on orphan drug designations (ODDs) and registered orphan drugs from 8th August 2000 to 10th September 2016 were collected from the Community Register of medicinal products for human use. Assessment history, product information and existence of paediatric investigation plans were searched and retrieved from the European Medicine Agency website...
August 14, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28818611/teasing-as-a-risk-factor-for-abnormal-eating-behaviours-a-prospective-study-in-an-adolescent-population
#20
Javier Plumed, Natalia Gimeno, María Barberá, Elías Ruiz, Llanos Conesa, Luis Miguel Rojo-Bofill, Lorenzo Livianos, Luis Rojo
INTRODUCTION: There are discrepancies in the literature about the role of teasing in the onset of eating pathology. This article aims to establish the influence of teasing in abnormal eating behaviors and attitudes in the adolescent population. MATERIAL AND METHODS: This is a two-year prospective study conducted in 7,167 adolescents between 13 and 15 years of age. In a first assessment, teasing about weight and teasing about abilities were measured by means of the POTS...
August 14, 2017: Revista de Psiquiatrí́a y Salud Mental
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