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https://www.readbyqxmd.com/read/28731943/the-impact-of-polypharmacy-on-patient-outcomes-in-older-adults-with-cancer
#1
Ginah Nightingale, Emily Skonecki, Manpreet K Boparai
Polypharmacy is prevalent in older adults with cancer and may be advantageous for the management of certain chronic disease states, but uncertainty exists regarding potential hazards and consequences. Cancer-related therapy adds to the prevalence of polypharmacy, which can lead to compromised cancer management plans (i.e., postoperative complications, treatment delays, and/or premature treatment discontinuation). Polypharmacy has been identified as one of the domains commonly included in the Comprehensive Geriatric Assessment likely because of the potential influence on health outcomes...
July 2017: Cancer Journal
https://www.readbyqxmd.com/read/28728547/community-based-initiatives-improving-critical-health-literacy-a-systematic-review-and-meta-synthesis-of-qualitative-evidence
#2
Liesbeth de Wit, Christine Fenenga, Cinzia Giammarchi, Lucia di Furia, Inge Hutter, Andrea de Winter, Louise Meijering
BACKGROUND: Critical health literacy enables older adults to make informed health decisions and take actions for the health and wellbeing of themselves and their community, within their own social and cultural context. A community-based approach has the potential to improve the critical health literacy of older adults and their communities. However, it is not clear how such initiatives consider critical health literacy. Therefore, this study explored how community-based initiatives address the critical health literacy of older adults and their communities...
July 20, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28726482/-great-powers-and-great-responsibilities-a-brief-comment-on-a-brief-mobile-app-reduces-nonsuicidal-and-suicidal-self-injury-evidence-from-three-randomized-controlled-trials-franklin-et-al-2016
#3
Emma Nielsen, Olivia J Kirtley, Ellen Townsend
Online and mobile mental health applications (apps) herald exciting new opportunities for the treatment and prevention of self-injurious thoughts and behaviors (SITBs). With such rapid technological advances, it is paramount that health care innovation not be achieved to the detriment of intervention quality. Franklin et al.'s (2016) therapeutic evaluative conditioning (TEC) app is a novel and timely addition to the mobile health landscape; uncommonly for such apps, it is evidence based. There are, however, several crucial challenges to be surmounted for TEC to be successful; arguably, interventions ought to build lasting skills that can be subsequently and consciously recruited to manage distress beyond the intervention period...
August 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28726481/a-randomized-controlled-trial-of-an-online-modular-active-learning-training-program-for-behavioral-activation-for-depression
#4
Ajeng J Puspitasari, Jonathan W Kanter, Andrew M Busch, Rachel Leonard, Shira Dunsiger, Shawn Cahill, Christopher Martell, Kelly Koerner
OBJECTIVE: This randomized-controlled trial assessed the efficacy of a trainer-led, active-learning, modular, online behavioral activation (BA) training program compared with a self-paced online BA training with the same modular content. METHOD: Seventy-seven graduate students (M = 30.3 years, SD = 6.09; 76.6% female) in mental health training programs were randomly assigned to receive either the trainer-led or self-paced BA training. Both trainings consisted of 4 weekly sessions covering 4 core BA strategies...
August 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28725843/identifying-and-understanding-the-health-information-experiences-and-preferences-of-individuals-with-tbi-sci-and-burn-injuries
#5
Nathan T Coffey, Ali A Weinstein, Cindy Cai, Jimmy Cassese, Rebecca Jones, Dahlia Shaewitz, Steven Garfinkel
INTRODUCTION: Traumatic brain injury, spinal cord injury, and burn injury can cause lifelong disability and changes in quality of life. In order to meet the challenges of postinjury life, various types of health information are needed. We sought to identify preferred sources of health information and services for persons with these injuries and discover how accessibility could be improved. METHODS: Thirty-three persons with injury participated in semistructured interviews...
September 2016: Journal of patient experience
https://www.readbyqxmd.com/read/28725641/mechanisms-mediating-pediatric-severe-asthma-and-potential-novel-therapies
#6
REVIEW
Aldara Martin Alonso, Sejal Saglani
Although a rare disease, severe therapy-resistant asthma in children is a cause of significant morbidity and results in utilization of approximately 50% of health-care resources for asthma. Improving control for children with severe asthma is, therefore, an urgent unmet clinical need. As a group, children with severe asthma have severe and multiple allergies, steroid resistant airway eosinophilia, and significant structural changes of the airway wall (airway remodeling). Omalizumab is currently the only add-on therapy that is licensed for use in children with severe asthma...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28722761/a-meta-ethnographic-synthesis-of-midwives-and-nurses-experiences-of-adverse-labour-and-birth-events
#7
REVIEW
Rakime Elmir, Jackie Pangas, Hannah Dahlen, Virginia Schmied
INTRODUCTION: Health professionals are frequently exposed to traumatic events due to the nature of their work. While traumatic and adverse labour and birth events experienced by women are well researched, less attention has been given to midwives' and nurses' experiences of these events and the impact it has on their lives. AIM: To undertake a meta-ethnographic study of midwives' and nurses' experiences of adverse labour and birth events. METHODS: Scopus, CINHAL PLUS, MEDLINE and PUBMED databases were searched using subject headings and keywords...
July 19, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28722615/assessing-the-short-term-global-health-experience-a-cross-sectional-study-of-demographics-socioeconomic-factors-and-disease-prevalence
#8
Olivia Geen, Allison Pumputis, Cristina Kochi, Andrew Costa, Karl Stobbe
Interest in short-term global health experiences to underserviced populations has grown rapidly in the last few decades. However, there remains very little research on what participants can expect to encounter. At the same time, it has been suggested that in order for physicians and workers to provide safe and effective care, volunteers should have a basic understanding of local culture, health systems, epidemiology, and socioeconomic needs of the community before arriving. Our objective was to add to the limited literature on what short-term global health trips can expect to encounter through a cross-sectional study of patient demographics, socioeconomic markers, and the prevalence of diseases encountered on a short-term medical service trip to Lima, Peru...
June 12, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28722602/associations-between-household-latrines-and-the-prevalence-of-diarrhea-in-idiofa-democratic-republic-of-the-congo-a-cross-sectional-study
#9
Seungman Cha, Jae Eun Lee, Dong Sik Seo, Byoung Mann Park, Paul Mansiangi, Jae-Sang Hwang, Jungwook Lee
Despite the importance of sanitation, few studies have assessed the effects of latrines on the health outcomes of children under 5 years of age. We assessed the relations between latrine coverage and the prevalence of diarrhea in children under 4 years of age. In this cross-sectional study, we analyzed the baseline data obtained as part of a longitudinal survey targeting 720 households in Idiofa, Bandundu, Democratic Republic of the Congo. We categorized latrines according to the presence of each major component and investigated whether diarrhea prevalence of children under 4 years of age is associated with latrine availability and improvement...
June 12, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28722278/non-physician-health-care-workers-and-voluntary-blood-donation-an-ambiguous-relationship
#10
N Sousos, S Sfyridou, D Adamidou, T-A Vyzantiadis, M Karadosidou, A Filippou, T Karafoulidou, M Chouridi, S Theodoridou
OBJECTIVES: This study aims to assess the knowledge, attitude and practice (KAP) of voluntary blood donation (BD) among the non-physician health-care workers of our institution, to investigate the relationship between these parameters and to determine the predictors of BD practice. BACKGROUND: KAP surveys provide a popular context-specific evidence base for the development of blood transfusion services' strategies and interventions to promote voluntary, non-remunerated BD...
July 19, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28722217/personal-and-situational-predictors-of-everyday-snacking-an-application-of-temporal-self-regulation-theory
#11
Katherine G Elliston, Stuart G Ferguson, Benjamin Schüz
OBJECTIVES: This study aims at testing predictions derived from temporal self-regulation theory (TST) in relation to discretionary food choices (snacks). TST combines a motivational sphere of influence (cognitions and temporal valuations resulting in intentions) with a momentary sphere (encompassing social and physical environmental cues). This dual approach differs from current health behaviour theories, but can potentially improve our understanding of the interplay of personal and environmental factors in health behaviour self-regulation...
July 19, 2017: British Journal of Health Psychology
https://www.readbyqxmd.com/read/28721463/exstrophy-bladder-reconstruction-or-diversion-for-the-underprivileged
#12
REVIEW
Yogesh Kumar Sarin, Virender Sekhon
The surgical techniques for management of bladder exstrophy epispadias complex have evolved from staged reconstruction, complete primary repair to radical mobilization. Post-operative complications add to the multiplicity of surgical procedures at each step. The end results are variable with many achieving continence rates of 85-89% only after bladder augmentation and clean intermittent catheterization. The situation is further complicated in resource-poor settings, where illiteracy and poverty are the driving factors for choosing a single operative procedure for creation of low pressure reservoir aiming at upper tract preservation and good primary continence...
July 18, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28721009/patient-profiles-and-clinical-utility-of-mepolizumab-in-severe-eosinophilic-asthma
#13
REVIEW
Pranabashis Haldar
Mepolizumab (Nucala(®)) is an effective and specific anti-eosinophil molecular therapy that has recently been approved as add-on therapy for the management of severe eosinophilic asthma by the US Food and Drug Administration (FDA), European Medicines Agency (EMA; European Union) and more recently National Institute for Health and Care Excellence (NICE; UK). It is one of several molecular therapies in development for this indication and is illustrative of the strategic trajectory for pharmaceutical drug development taken over the past decade in several disease areas...
2017: Biologics: Targets & Therapy
https://www.readbyqxmd.com/read/28720513/ahrq-series-on-complex-intervention-systematic-reviews-paper-7-prisma-ci-elaboration-explanation
#14
Jeanne-Marie Guise, Mary Butler, Christine Chang, Meera Viswanathan, Terri Pigott, Peter Tugwell
BACKGROUND: Complex interventions are widely used in health care, public health, education, criminology, social work, business, and welfare. They have increasingly become the subject of systematic reviews and are challenging to effectively report. The Complex Interventions Methods Workgroup developed an extension to the Preferred Reporting Items for Systematic Reviews and Meta-analyses for Complex Interventions called PRISMA-CI. RATIONALE: Following the EQUATOR Network guidance for PRISMA extensions, this Explanation and Elaboration document accompanies the PRISMA-CI checklist to promote consistency in reporting of systematic reviews of complex interventions...
June 30, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28719364/is-there-a-link-between-self-perceived-stress-and-physical-activity-levels-in-scottish-adolescents
#15
Joe Cowley, John Kiely, Dave Collins
Purpose Accumulating life stress is a driving factor underlying the most pervasive, incapacitating health conditions in 21st century, First World societies. The most widely supported strategy, for remediating the negative health consequences of elevated life stress, is physical activity (PA). Evidence also suggests accumulating life stress impedes PA uptake. Thus, ironically, persistently elevated life stress not only negatively impacts multiple dimensions of health, simultaneously it may also reduce likelihood of participation in the most effective remediating strategy, PA...
July 18, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28719299/conventional-wisdom-versus-actual-outcomes-challenges-in-the-conduct-of-an-ebola-vaccine-trial-in-liberia-during-the-international-public-health-emergency
#16
Gregg S Larson, Beth R Baseler, Marie L Hoover, Jerome F Pierson, Jemee K Tegli, Melvin P Johnson, Mark W S Kieh, Laura A McNay, Wissedi Sio Njoh
Clinical trials are challenging endeavors. Planning and implementing an investigational vaccine trial in Liberia, in the midst of an Ebola virus disease (EVD) epidemic that World Health Organization classified a public health emergency of international concern, presented extraordinary challenges. Normally, years of preparation and a litany of tasks lay the groundwork for a successful, randomized, blinded, placebo-controlled trial focused on safety and efficacy. Difficult research settings, unpredictable events, and other unique circumstances can add complexity...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28716452/the-proliferation-of-sexual-health-diverse-social-problems-and-the-legitimation-of-sexuality
#17
Steven Epstein, Laura Mamo
Especially since the 1990s, the term sexual health has flourished in professional, commercial, and lay domains. Yet the more the phrase has become visible, the greater the mutability in its meanings. These developments matter for an understanding of healthism-the idea that modern individuals are enjoined to recognize a moral obligation to maximize their health. Theorists of healthism have paid relatively little attention to sexuality and its frequent rendering as controversial, illegitimate, or stigmatizing...
June 29, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28716072/effect-of-prenatal-exposure-to-maternal-cortisol-and-psychological-distress-on-infant-development-in-bengaluru-southern-india-a-prospective-cohort-study
#18
Anita Nath, Gudlavalleti Venkata Satyanarayana Murthy, Giridhara R Babu, Gian Carlo Di Renzo
BACKGROUND: The mental health status of a pregnant woman and its consequent impact on foetal well being is not given much importance compared to the risk imposed by obstetric complications and medical conditions. Maternal psychological distress is a major public health problem and needs timely detection and intervention to prevent any adverse pregnancy outcome. There is ample evidence from literature that justifies the association of prenatal maternal mental stress and elevated cortisol with delayed infant motor and cognitive development; evidence from India being rather limited...
July 17, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28715990/single-subject-studies-in-translational-nutrition-research
#19
Nicholas J Schork, Laura H Goetz
There is a great deal of interest in personalized, individualized, or precision interventions for disease and health-risk mitigation. This is as true of nutrition-based intervention and prevention strategies as it is for pharmacotherapies and pharmaceutical-oriented prevention strategies. Essentially, technological breakthroughs have enabled researchers to probe an individual's unique genetic, biochemical, physiological, behavioral, and exposure profile, allowing them to identify very specific and often nuanced factors that an individual might possess, which may make it more or less likely that he or she responds favorably to a particular intervention (e...
July 17, 2017: Annual Review of Nutrition
https://www.readbyqxmd.com/read/28715752/switching-to-sanitation-understanding-latrine-adoption-in-a-representative-panel-of-rural-indian-households
#20
Diane Coffey, Dean Spears, Sangita Vyas
Open defecation, which is still practiced by about a billion people worldwide, is one of the most compelling examples of how place influences health in developing countries. Efforts by governments and development organizations to address the world's remaining open defecation would be greatly supported by a better understanding of why some people adopt latrines and others do not. We analyze the 2005 and 2012 rounds of the India Human Development Survey (IHDS), a nationally representative panel of households in India, the country which is home to 60% of the people worldwide who defecate in the open...
July 6, 2017: Social Science & Medicine
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