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https://www.readbyqxmd.com/read/28543991/sensitivity-and-specificity-of-plasma-alt-alp-and-bile-acids-for-hepatitis-in-labrador-retrievers
#1
K Dirksen, I A Burgener, J Rothuizen, T S G A M van den Ingh, L C Penning, B Spee, H Fieten
BACKGROUND: Biochemical indicators for diagnosing liver disease are plasma alanine aminotransferase activity (ALT), alkaline phosphatase activity (ALP), and bile acid concentration (BA). OBJECTIVES: To determine the sensitivity and specificity of ALT, ALP, and BA for detecting primary hepatitis (PH) in clinically healthy Labrador retrievers and investigate whether ALT and ALP can discriminate between dogs with PH and nonspecific reactive hepatitis (RH). ANIMALS: 191 clinically healthy and 51 clinically ill Labrador retrievers with hepatic histopathology...
May 23, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28538846/-clinical-and-microbiological-study-of-catheter-associated-urinary-tract-infections-in-internal-medicine-services-of-a-venezuelan-university-hospital
#2
Pedro Quijada-Martínez, Ana Flores-Carrero, Indira Labrador, María Araque
Objectives: To determine the clinical and microbiological characteristics of catheter-associated urinary tract infections (CA-UTI) in patients admitted to the Internal Medicine services of the Hospital Universitario de Los Andes (HULA), Mérida, Venezuela and to establish the clonal distribution of multi-resistant Enterobacteriaceae that produce this infection. Materials and Methods: Seventy-three adult patients with bladder catheterization were studied between January and July 2015...
January 2017: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/28534468/effect-of-wearing-a-telemetry-jacket-on-behavioral-and-physiologic-parameters-of-dogs-in-the-open%C3%A2-field-test
#3
Richard E Fish, Melanie L Foster, Margaret E Gruen, Barbara L Sherman, David C Dorman
Safety pharmacology studies in dogs often integrate behavioral assessments made using video recording with physiologicmeasurements collected by telemetry. However, whether merely wearing the telemetry vest affects canine behavior and otherparameters has not been evaluated. This pilot study assessed the effect of a telemetry vest on behavioral and physiologic responses to an environmental stressor, the sounds of a thunderstorm, in Labrador retrievers. Dogs were assigned to one of 2 experimental groups (Vest and No-Vest, n = 8 dogs per group) by using a matched pairs design, with a previously determined,sound-associated anxiety score as the blocking variable...
May 22, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28514049/canine-cutaneous-plasmacytosis-21-cases-2005-2015
#4
B O Boostrom, A S Moore, C J DeRegis, C Robat, K Freeman, D H Thamm
BACKGROUND: Cutaneous plasmacytosis (CP) is a syndrome of multiple cutaneous plasma cell tumors, in the absence of multiple myeloma. Although rare in both humans and dogs, treatment recommendations are usually extrapolated from multiple myeloma protocols. To date, no case series of CP have been described in the veterinary literature. HYPOTHESIS/OBJECTIVES: To describe clinical presentation, determine treatment response rates and duration, and report overall survival of dogs with CP...
May 17, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28511878/epidemiological-multicentre-study-on-the-education-provided-to-patients-with-type-2-diabetes-mellitus-in-the-spanish-health-care-system-the-forma2-study
#5
J A García-Donaire, J Franch-Nadal, P Rodríguez-Fortúnez, E Labrador-Barba, M L Orera-Peña, M Rodríguez de Miguel
PURPOSE: The purpose of the present study was to characterize the education that patients with type 2 diabetes mellitus receive, and to identify differences as regards the presence of insulin therapy or not. METHODS: This crossover, multicentre and descriptive study involved 1066 Spanish physicians who completed a questionnaire on Internet. RESULTS: The physicians that responded had a mean of 26.0 years of experience in healthcare, and mainly worked in a walk-in clinic in an urban area...
May 13, 2017: Semergen
https://www.readbyqxmd.com/read/28508126/what-s-the-point-golden-and-labrador-retrievers-living-in-kennels-do-not-understand-human-pointing-gestures
#6
Biagio D'Aniello, Alessandra Alterisio, Anna Scandurra, Emanuele Petremolo, Maria Rosaria Iommelli, Massimo Aria
In many studies that have investigated whether dogs' capacities to understand human pointing gestures are aspects of evolutionary or developmental social competences, family-owned dogs have been compared to shelter dogs. However, for most of these studies, the origins of shelter dogs were unknown. Some shelter dogs may have lived with families before entering shelters, and from these past experiences, they may have learned to understand human gestures. Furthermore, there is substantial variation in the methodology and analytic approaches used in such studies (e...
May 15, 2017: Animal Cognition
https://www.readbyqxmd.com/read/28501814/a-scoping-review-protocol-on-social-participation-of-indigenous-elders-intergenerational-solidarity-and-their-influence-on-individual-and-community-wellness
#7
Chantal Viscogliosi, Hugo Asselin, Suzy Basile, Yves Couturier, Marie-Josée Drolet, Dominique Gagnon, Jill Torrie, Mélanie Levasseur
INTRODUCTION: Indigenous elders have traditionally played an important role in maintaining social cohesion within their communities. Today, part of this role has been taken over by government social and healthcare services, but they are having limited success in addressing social challenges. Increasing elders' social participation and intergenerational solidarity might foster community development and benefit young people, families, communities and the elders themselves. However, knowledge of the contribution of elders' social participation and intergenerational solidarity to wellness is scattered and needs to be synthesised...
May 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/28483888/alignment-of-canadian-primary-care-with-the-patient-medical-home-model-a-qualico-pc-study
#8
Alan Katz, Nicole Herpai, Glenys Smith, Kris Aubrey-Bassler, Mylaine Breton, Antoine Boivin, William Hogg, Baukje Miedema, Jocelyn Pang, Walter P Wodchis, Sabrina T Wong
PURPOSE: The patient medical home (PMH) model aims to improve patient satisfaction and health outcomes in Canada, but since its introduction in 2009, there has been no evaluation of the extent to which primary care conforms with PMH attributes. Our objective was to compare current primary care across Canada with the 10 goals of the PMH model. METHODS: A cross-sectional survey of primary care organization and delivery was conducted in Canadian provinces to evaluate the PMH-based attributes of primary care practices...
May 2017: Annals of Family Medicine
https://www.readbyqxmd.com/read/28470741/canine-oral-mucosa-evaluation-as-a-potential-autograft-tissue-for-the-treatment-of-unresponsive-keratoconjunctivitis-sicca
#9
Rose L Cherry, Jodi D Smith, Gil Ben-Shlomo
PURPOSE: Labial mucosa transplantation for the treatment of canine keratoconjunctivitis sicca (KCS) has been reported recently. Postoperative alleviation of clinical signs was noted and assumed to be the result of labial salivary glands providing lubrication to the ocular tissue. The aim of this study was to evaluate the presence of minor salivary glands (MSG) in the canine oral mucosa. METHODS: Oral mucosal biopsies were collected from six dogs that died (n = 1) or were euthanized (n = 5) for reasons unrelated to this study...
May 4, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/28469428/using-electronic-medical-record-to-identify-patients-with-dyslipidemia-in-primary-care-settings-international-classification-of-disease-code-matters-from-one-region-to-a-national-database
#10
Justin Oake, Erfan Aref-Eshghi, Marshall Godwin, Kayla Collins, Kris Aubrey-Bassler, Pauline Duke, Masoud Mahdavian, Shabnam Asghari
OBJECTIVE: To assess the validity of the International Classification of Disease (ICD) codes for identifying patients with dyslipidemia in electronic medical record (EMR) data. METHODS: The EMRs of patients receiving primary care in St. John's, Newfoundland and Labrador (NL), Canada, were retrieved from the Canadian Primary Care Sentinel Surveillance Network database. International Classification of Disease codes were first compared with laboratory lipid data as an independent criterion standard, and next with a "comprehensive criterion standard," defined as any existence of abnormal lipid test, lipid-lowering medication record, or dyslipidemia ICD codes...
2017: Biomedical Informatics Insights
https://www.readbyqxmd.com/read/28460748/disease-burden-in-four-populations-of-dog-and-cat-breeds-compared-to-mixed-breed-dogs-and-european-shorthair-cats
#11
S F A Keijser, L E Meijndert, H Fieten, B J Carrière, F G van Steenbeek, P A J Leegwater, J Rothuizen, M Nielen
Current public and professional opinion is that many dog breeds suffer from health issues related to inherited diseases or extreme phenotypes. The aim of this historical comparative observational study was to evaluate the breed-related disease burden in three purebred dog populations (Chihuahua, French bulldog, Labrador retriever) and one purebred cat breed (Persian cats) in the Netherlands by comparison to a control population of mixed-breed dogs and European Shorthair cats. A qualitative query was performed, consisting of a literature review and collecting the expert opinions of University veterinary specialists, to gather insight into potential diseases of the study population...
May 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28460746/incidence-rates-and-risk-factor-analyses-for-owner-reported-vomiting-and-diarrhoea-in-labrador-retrievers-findings-from-the-dogslife-cohort
#12
Carys A Pugh, B Mark de C Bronsvoort, Ian G Handel, Damon Querry, Erica Rose, Kim M Summers, Dylan N Clements
Dogslife collects data directly from owners of Labrador Retrievers across the UK including information regarding signs of illness irrespective of whether the signs precipitated a veterinary visit. In December 2015, the cohort comprised 6084 dogs aged up to six years and their owners had made 2687 and 2601 reports of diarrhoea and vomiting respectively. The co-occurrence of vomiting and diarrhoea with other signs was described and the frequencies and durations of the two signs were examined with reference to veterinary visitation...
May 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28459846/gene-expression-patterns-in-the-progression-of-canine-copper-associated-chronic-hepatitis
#13
Karen Dirksen, Bart Spee, Louis C Penning, Ted S G A M van den Ingh, Iwan A Burgener, Adrian L Watson, Marian Groot Koerkamp, Jan Rothuizen, Frank G van Steenbeek, Hille Fieten
Copper is an essential trace element, but can become toxic when present in abundance. The severe effects of copper-metabolism imbalance are illustrated by the inherited disorders Wilson disease and Menkes disease. The Labrador retriever dog breed is a novel non-rodent model for copper-storage disorders carrying mutations in genes known to be involved in copper transport. Besides disease initiation and progression of copper accumulation, the molecular mechanisms and pathways involved in progression towards copper-associated chronic hepatitis still remain unclear...
2017: PloS One
https://www.readbyqxmd.com/read/28458128/the-role-of-safety-signals-in-fear-extinction-an-analogue-study
#14
Juan C Restrepo-Castro, Leonidas Castro-Camacho, Francisco Javier Labrador
BACKGROUND AND OBJECTIVES: Safety signals are conditioned inhibitory stimuli that indicate the absence of unconditioned stimuli. It is not clear whether the presence of safety signals is detrimental or beneficial in extinction-based interventions. The purpose of this study was to evaluate the effect of safety signals on autonomic and expectancy fear-related responses. METHODS: Following the conditional discrimination paradigm (AX +, BX-), undergraduate students (N = 48) underwent an aversive conditioning procedure, while safety signals were experimentally created...
April 19, 2017: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/28447709/-atypical-cushing-s-syndrome-in-a-dog-a-case-report
#15
Stefanie Hoffrogge, Lena Fels, Marion Schmicke, Reinhard Mischke
In a 12-year-old male Labrador Retriever, presented due to other disease symptoms, clinical signs of hyperadrenocorticism (polyuria, polydipsia, abdominal distention, muscle atrophy) were an incidental finding. Abnormal laboratory results and sonographic findings of the adrenal glands, but negative low-dose dexamethasone suppression tests with low basal cortisol concentrations, a negative andrenocorticotropic hormone (ACTH)-stimulation test and exclusion of iatrogenic hyperadrenocorticism, suggested an atypical hyperadrenocorticism (AHAC)...
April 27, 2017: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/28447394/estimation-of-maintenance-energy-requirements-in-german-shepherd-and-labrador-retriever-dogs-in-bangalore-india
#16
H S Madhusudhan, K Chandrapal Singh, U Krishnamoorthy, K G Umesh, R Butterwick, D Wrigglesworth
Maintenance energy requirements (MERs) were calculated for 17 German shepherd and 20 Labrador retriever adult dogs using an in-home prospective dietary trial. The dogs were fed the same dry pet food and body weight, food intake, body condition score and physical activity were monitored for 10 weeks. Labrador retrievers were significantly heavier and had higher body condition scores than German shepherd dogs, but there was no difference between males and females within each group. Body weights remained stable over the study period, with an average daily gain of 9...
April 26, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28444793/dietary-mannoheptulose-does-not-alter-glucose-or-lipid-metabolism-in-adult-labrador-retrievers
#17
L L McKnight, J France, D Wright, G Davenport, A K Shoveller
Mannoheptulose (MH), a glycolytic inhibitor, has been preliminarily investigated as a novel functional food ingredient for dogs. This study aimed to determine the effects of dietary MH, delivered as an extract of un-ripened avocados, on fatty acid and glucose kinetics in healthy adult Labrador Retriever dogs (n = 12 dogs). The study was a double-blindcrossover with each dog receiving both dietary treatments, control (CON) and MH (400 mg/kg of diet), in random order. Glucose and glycerol plasma turnover (Ra) and oxidation (Ox) were measured in fasting and in response to repeated meal feeding ("fed") with stable isotope tracers (U-(13) C-glucose, 1,1,2,3,3-D5 -glycerol) and indirect calorimetry...
April 26, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28441128/early-career-work-location-of-memorial-university-medical-graduates-why-the-decline-in-rural-practice
#18
Maria Mathews, Dana Ryan, Asoka Samarasena
INTRODUCTION: In a previous study, we found a decline in the proportion of Memorial University of Newfoundland (MUN) medical alumni practising in rural areas, particularly in Newfoundland and Labrador. The current study focused on the work location of recent graduates and examined the predictors of working in rural Canada and in rural Newfoundland and Labrador within the first 15 years following graduation. METHODS: We linked data from graduating class lists and the alumni and postgraduate databases with Scott's Medical Database to create a record of all graduates from 1973 to 2008, including their work location...
2017: Canadian Journal of Rural Medicine
https://www.readbyqxmd.com/read/28435229/medication-adherence-and-persistence-in-type-2-diabetes-mellitus-perspectives-of-patients-physicians-and-pharmacists-on-the-spanish-health-care-system
#19
Elena Labrador Barba, Marta Rodríguez de Miguel, Antonio Hernández-Mijares, Francisco Javier Alonso-Moreno, Maria Luisa Orera Peña, Susana Aceituno, María José Faus Dader
OBJECTIVE: A good relationship between diabetes patients and their health care team is crucial to ensure patients' medication adherence and self-management. To this end, we aimed to identify and compare the views of type 2 diabetes mellitus (T2DM) patients, physicians and pharmacists concerning the factors and strategies that may be associated with, or could improve, medication adherence and persistence. METHODS: An observational, cross-sectional study was conducted using an electronic self-administered questionnaire comprising 11 questions (5-point Likert scale) concerning factors and strategies related to medication adherence...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/28432368/indoor-radon-in-micro-geological-setting-of-an-indigenous-community-in-canada-a-pilot-study-for-hazard-identification
#20
Atanu Sarkar, Derek Hc Wilton, Erica Fitzgerald
BACKGROUND: Radon is the second leading cause of lung cancer after smoking. In Canada, the health authorities have no access to comprehensive profile of the communities built over uranium-rich micro-geological settings. The present indoor radon monitoring guideline is unable to provide an accurate identification of health hazards due to discounting several parameters of housing characteristics. OBJECTIVE: To explore indoor radon levels in a micro-geological setting known for high uranium in bedrock and to develop a theoretical model for a revised radon testing protocol...
April 2017: International Journal of Occupational and Environmental Medicine
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