keyword
MENU ▼
Read by QxMD icon Read
search

Labrador

keyword
https://www.readbyqxmd.com/read/29155221/motor-axon-guidance-in-drosophila
#1
REVIEW
Aref Arzan Zarin, Juan-Pablo Labrador
The Drosophila motor system starts to assemble during embryonic development. It is composed of 30 muscles per abdominal hemisegment and 36 motor neurons assembling into nerve branches to exit the CNS, navigate within the muscle field and finally establish specific connections with their target muscles. Several families of guidance molecules that play a role controlling this process as well as transcriptional regulators that program the behavior of specific motoneurons have been identified. In this review we summarize the role of both groups of molecules in the motor system as well as their relationship where known...
November 16, 2017: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/29152242/comparative-assessment-of-canine-origin-lactobacillus-johnsonii-cpn23-and-dairy-origin-lactobacillus-acidophillus-ncdc-15-for-nutrient-digestibility-faecal-fermentative-metabolites-and-selected-gut-health-indices-in-dogs
#2
Sachin Kumar, Ashok K Pattanaik, Shalini Sharma, Reema Gupta, Sunil E Jadhav, Narayan Dutta
The present experiment was undertaken to validate a probiotic of canine origin for its potential use in dogs. A total of fifteen adult female Labrador dogs were allocated to three equal groups and fed a basal diet without probiotic (control) or with probiotic of either canine (Lactobacillus johnsonii CPN23; cPRO) or dairy (L. acidophilus NCDC 15; dPRO) origin for 9 weeks. The digestibility of most macronutrients remained similar among the groups; however, fibre digestibility was improved (P = 0·034) in dogs receiving cPRO...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/29149307/tumour-tif1-mutations-and-loss-of-heterozygosity-related-to-cancer-associated-myositis
#3
Iago Pinal-Fernandez, Berta Ferrer-Fabregas, Ernesto Trallero-Araguas, Eva Balada, Maria Angeles Martínez, Jose César Milisenda, Gloria Aparicio-Español, Moises Labrador-Horrillo, Vicente Garcia-Patos, Josep M Grau-Junyent, Albert Selva-O'Callaghan
Objectives: To analyse the influence of genetic alterations and differential expression of transcription intermediary factor 1 ( TIF1 ) genes in the pathophysiology of cancer-associated myositis (CAM). Methods: Paired blood and tumour DNA samples from patients with anti-TIF1γ-positive CAM and from controls were analysed by whole-exome sequencing for the presence of somatic mutations and loss of heterozygosity (LOH) in their TIF1 genes. The genesis and maintenance of the autoimmune process were investigated immunohistochemically by studying TIF1γ expression in the different tissues involved in CAM (skin, muscle and tumour) based on the immunohistochemical H-score...
November 14, 2017: Rheumatology
https://www.readbyqxmd.com/read/29145101/the-distribution-and-trends-of-persistent-organic-pollutants-and-mercury-in-marine-mammals-from-canada-s-eastern-arctic
#4
REVIEW
Tanya M Brown, Robie W Macdonald, Derek C G Muir, Robert J Letcher
Arctic contaminant research in the marine environment has focused on organohalogen compounds and mercury mainly because they are bioaccumulative, persistent and toxic. This review summarizes and discusses the patterns and trends of persistent organic pollutants (POPs) and mercury in ringed seals (Pusa hispida) and polar bears (Ursus maritimus) in the Eastern Canadian Arctic relative to the rest of the Canadian Arctic. The review provides explanations for these trends and looks at the implications of climate-related changes on contaminants in these marine mammals in a region that has been reviewed little...
November 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29132004/how-are-perceptions-associated-with-water-consumption-in-canadian-inuit-a-cross-sectional-survey-in-rigolet-labrador
#5
Carlee J Wright, Jan M Sargeant, Victoria L Edge, James D Ford, Khosrow Farahbakhsh, Inez Shiwak, Charlie Flowers, Allan C Gordon, Sherilee L Harper
Concerns regarding the safety and aesthetic qualities of one's municipal drinking water supply are important factors influencing drinking water perceptions and consumption patterns (i.e. sources used and daily volume of consumption). In northern Canada, Inuit communities face challenges with drinking water quality, and many Inuit have reported concerns regarding the safety of their drinking water. The objectives of this research were to describe perceptions of municipal tap water, examine use of water sources and changes following the installation of a potable water dispensing unit (PWDU) in 2014, and identify factors associated with water consumption in the Inuit community of Rigolet...
November 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29128861/atrial-cardiomyopathy-in-an-adult-labrador-retriever-dog
#6
E Bomassi, J Rousselot, S Libermann, I Raymond Letron, S Etchepareborde, C Misbach
A 7-year-old castrated male Labrador retriever was examined for a 10-day history of weakness and syncope. Physical examination revealed bradycardia and a grade III/VI left apical systolic heart murmur. Electrocardiography demonstrated bradycardia, absence of P waves and an atrio-ventricular nodal escape rhythm. Echocardiography revealed marked biatrial enlargement. Thoracic radiographs showed no evidence of pulmonary edema. Routine plasma biochemistry and electrolytes, basal serum cortisol, total thyroxin concentration, and complete blood count were within normal limits...
November 2017: Schweizer Archiv Für Tierheilkunde
https://www.readbyqxmd.com/read/29128380/low-influenza-vaccine-effectiveness-and-the-effect-of-previous-vaccination-in-preventing-admission-with-a-h1n1-pdm09-or-b-victoria-lineage-in-patients-60-years-old-or-older-during-the-2015-2016-influenza-season
#7
Joan Puig-Barberà, Beatriz Guglieri-López, Miguel Tortajada-Girbés, F Xavier López-Labrador, Mario Carballido-Fernández, Joan Mollar-Maseres, Germán Schwarz-Chavarri, Víctor Baselga-Moreno, Ainara Mira-Iglesias, Javier Díez-Domingo
BACKGROUND: The 2015/2016 influenza season was characterized in Europe by the circulation of A(H1N1)pdm09 clade 6B.1 and B/Victoria-lineage influenza viruses. The components of the vaccines used in the current and past two seasons in the Valencia region were similar but not well matched to the 2015/2016 dominant influenza-circulating strains. We estimate influenza vaccine effectiveness (IVE) and interference of previous vaccination in preventing admission with A(H1N1)pdm09 or B/Victoria-lineage in this particular season...
November 8, 2017: Vaccine
https://www.readbyqxmd.com/read/29126143/understanding-how-dogs-age-longitudinal-analysis-of-markers-of-inflammation-immune-function-and-oxidative-stress
#8
Janet E Alexander, Alison Colyer, Richard M Haydock, Michael G Hayek, JeanSoon Park, Rafael de Cabo
As in human populations, advances in nutrition and veterinary care have led to an increase in the lifespan of companion animals. Detrimental physiological changes occurring later in life must be understood before interventions can be made to slow or reduce them. One important aspect of human aging is upregulation of the inflammatory response and increase in oxidative damage resulting in pathologies linked to chronic inflammation. To determine whether similar processes occur in the aging dog, changes in markers of inflammation and oxidative stress were investigated in 80 Labrador retrievers from adulthood to the end of life...
November 6, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29120316/weighing-in-on-canadian-school-based-vision-screening-a-call-for-action
#9
Katie P Bennett, Wendy Maloney
Vision-screening programs are designed to detect common causes of visual impairment and increase the likelihood of early diagnosis and treatment. In the health authority Eastern Health - Newfoundland and Labrador, public health leaders raised a concern about the efficiency and effectiveness of the current non-routine, opportunistic vision screening protocol for school-aged children. An environmental scan of screening practices and programs across Canada was conducted, yielding a wide range of inconsistencies with respect to program type, target population, and screening tools...
November 9, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/29103899/perturbation-of-the-t-cell-receptor-repertoire-occurs-with-increasing-age-in-dogs
#10
Angela Holder, Samantha M Mirczuk, Robert C Fowkes, Donald B Palmer, Richard Aspinall, Brian Catchpole
Immunosenescence is the gradual deterioration in immune system function associated with ageing. This decline is partly due to involution of the thymus, which leads to a reduction in the output of naive T cells into the circulating lymphocyte pool. Expansion of existing naive and memory T cell populations, to compensate for the reduction in thymic output, can lead to reduced diversity in the T cell repertoire with increasing age, resulting in impairment of immune responses to novel antigenic challenges, such as during infection and vaccination...
October 28, 2017: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/29096710/putting-research-in-place-an-innovative-approach-to-providing-contextualized-evidence-synthesis-for-decision-makers
#11
Stephen Bornstein, Rochelle Baker, Pablo Navarro, Sarah Mackey, David Speed, Melissa Sullivan
BACKGROUND: The Contextualized Health Research Synthesis Program (CHRSP), developed in 2007 by the Newfoundland and Labrador Centre for Applied Health Research, produces contextualized knowledge syntheses for health-system decision makers. The program provides timely, relevant, and easy-to-understand scientific evidence; optimizes evidence uptake; and, most importantly, attunes research questions and evidence to the specific context in which knowledge users must apply the findings. METHODS: As an integrated knowledge translation (KT) method, CHRSP: Involves intensive partnerships with senior healthcare decision makers who propose priority research topics and participate on research teams; Considers local context both in framing the research question and in reporting the findings; Makes economical use of resources by utilizing a limited number of staff; Uses a combination of external and local experts; and Works quickly by synthesizing high-level systematic review evidence rather than primary studies...
November 2, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/29081760/oxytocin-and-cortisol-levels-in-dog-owners-and-their-dogs-are-associated-with-behavioral-patterns-an-exploratory-study
#12
Maria Petersson, Kerstin Uvnäs-Moberg, Anne Nilsson, Lise-Lotte Gustafson, Eva Hydbring-Sandberg, Linda Handlin
We have previously shown that dog-owner interaction results in increasing oxytocin levels in owners and dogs, decreasing cortisol levels in owners but increasing cortisol levels in dogs. The present study aimed to further investigate whether oxytocin and cortisol levels in the previously tested owners and dogs were associated with their behaviors during the interaction experiment. Ten female volunteer dog-owners and their male Labrador dogs participated in a 60 min interaction experiment with interaction taking place during 0-3 min and blood samples for analysis of oxytocin and cortisol were collected at 0, 1, 3, 5, 15, 30, and 60 min...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29071254/breast-cancer-surgical-treatment-choices-in-newfoundland-and-labrador-canada-patient-and-surgeon-perspectives
#13
Etchegary Holly, Dicks Elizabeth, McCrate Farah, Powell Erin, Chafe Joanne, Roome Rebecca, Simmonds Charlene
BACKGROUND: Breast cancer remains the second-leading cause of cancer death among Canadian women. Treatment for breast cancer often includes surgery. Many women have a choice between mastectomy (MT; removal of the entire breast) or breast conserving surgery (BCS; removal of the tumour and some noncancerous breast tissue) followed by radiation. However, Newfoundland and Labrador consistently has a higher rate of mastectomies than the rest of Canada. In this project, we aim to better understand that trend...
September 21, 2017: Journal of Public Health Research
https://www.readbyqxmd.com/read/29066016/the-impact-of-access-barriers-on-fertility-treatment-decision-making-a-qualitative-study-from-the-perspectives-of-patients-and-service-providers
#14
Erika Maxwell, Maria Mathews, Shree Mulay
OBJECTIVE: The purpose of this study was to explore how barriers to accessing fertility services affect the treatment decisions made by fertility patients and service providers in Newfoundland and Labrador. METHODS: Semistructured, in-depth interviews were conducted with 11 patients across Newfoundland and with eight service providers from Newfoundland and Labrador Fertility Services (located in St. John's) to gather the perspectives of both patients and providers...
October 20, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29065293/genetics-ancient-dna-clarifies-population-histories-of%C3%A2-the-northeastern-margin-of-north-america
#15
Jennifer Raff
A new study of ancient mitochondrial DNA from Newfoundland and Labrador indicates that this region at the northeastern margin of North America was populated three times in succession by different indigenous groups. This research helps shed light on the movement of populations across the continent, following the initial peopling of the Americas.
October 23, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/29057571/cypa-and-emmprin-play-a-role-in-peri-implantitis
#16
Lei Yang, Qing Zhu, Jingjue Gong, Ming Xie, Ting Jiao
BACKGROUND: Cyclophilin A (CyPA) and Emmprin play important roles in peri-implantitis. However, their roles in the diagnosis and treatment of the disease are still unclear. PURPOSE: The aim of this split-mouth animal study was to describe variable trends of biomarkers during the progression of peri-implantitis and to define relationships among CyPA, Emmprin, and peri-implantitis. MATERIALS AND METHODS: Six male adult Labradors were used. The mandibular premolars and the first molar were extracted, and sixteen implants were placed after 3 months...
October 22, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29056703/complete-resolution-of-a-recurrent-canine-anal-sac-squamous-cell-carcinoma-with-palliative-radiotherapy-and-carboplatin-chemotherapy
#17
Antonio Giuliano, Jane Dobson, Sarah Mason
Anal sac squamous cell carcinoma (SCC) is a rare tumor in dogs. Only eight cases have been described in the literature, and previous reports of treatment only describe surgery or palliative treatment with non-steroidal anti-inflammatory drugs. We report a case of a 12-year-old female neutered Labrador with locally advanced anal sac SCC. The dog was treated with four cycles of carboplatin 300 mg/m² and four weekly fractions of 8.5 Gy radiation. The dog achieved a complete response, and one year later the dog is still alive and well with no evidence of tumor recurrence...
September 14, 2017: Veterinary Sciences
https://www.readbyqxmd.com/read/29056071/hidradenitis-suppurativa-a-novel-model-of-care-and-an-integrative-strategy-to-adopt-an-orphan-disease
#18
Wayne Gulliver, Ian D R Landells, David Morgan, Syed Pirzada
Unnecessary investigations, inappropriate treatment, worsening disease, and frustration for both patients and health care professionals are the hallmarks of hidradenitis suppurativa (HS) management. In light of a new treatment algorithm and biologic therapies made available to patients, an HS model of care is outlined in this article. The recommendations and management strategy presented here have been developed to help address the currently unmet needs of this patient population. The patient-centred model of care and disease management strategies were developed through the guidance and recommendations of HS medical experts in Newfoundland and Labrador...
October 1, 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29055560/plastic-pollution-in-the-labrador-sea-an-assessment-using-the-seabird-northern-fulmar-fulmarus-glacialis-as-a-biological-monitoring-species
#19
Stephanie Avery-Gomm, Jennifer F Provencher, Max Liboiron, Florence E Poon, Paul A Smith
Plastic is now one among one of the most pervasive pollutants on the planet, and ocean circulation models predict that the Arctic will become another accumulation zone. As solutions to address marine plastic emerge, is essential that baselines are available to monitor progress towards targets. The northern fulmar (Fulmarus glacialis), a widely-distributed seabird species, has been used as a biological monitor for plastic pollution in the North Sea, and could be a useful monitoring species elsewhere. We quantified plastic ingested by northern fulmars from the southeastern Canadian waters of the Labrador Sea with the objective of establishing a standardized baseline for future comparisons...
October 18, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/29054883/the-role-of-patient-and-physician-advocacy-in-reducing-wait-times-for-cancer-care-a-qualitative-analysis
#20
Maria Mathews, Donna Bulman, Dana Ryan
BACKGROUND: There is growing interest in the role of physician as health advocate; however, few studies have documented advocacy from the patient's perspective. To address this gap, we examined the experiences of patients with cancer from the onset of symptoms to the start of treatment in Newfoundland and Labrador and aimed to describe wait times and efforts to improve timeliness of care from the patients' perspective. METHODS: We conducted qualitative interviews with 60 participants aged 19 years or more with breast, colorectal, lung or prostate cancer who were recruited from a survey of patients with cancer that was carried out as an earlier part of a larger study...
October 17, 2017: CMAJ Open
keyword
keyword
26953
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"