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Anti-inflammatory food

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https://www.readbyqxmd.com/read/29333376/anti-inflammatory-and-anti-obesity-properties-of-food-bioactive-components-effects-on-adipose-tissue
#1
REVIEW
Shasika Jayarathne, Iurii Koboziev, Oak-Hee Park, Wilna Oldewage-Theron, Chwan-Li Shen, Naima Moustaid-Moussa
Obesity is an epidemic and costly disease affecting 13% of the adult population worldwide. Obesity is associated with adipose tissue hypertrophy and hyperplasia, as well as pathologic endocrine alterations of adipose tissue including local and chronic systemic low-grade inflammation. Moreover, this inflammation is a risk factor for both metabolic syndrome (MetS) and insulin resistance. Basic and clinical studies demonstrate that foods containing bioactive compounds are capable of preventing both obesity and adipose tissue inflammation, improving obesity-associated MetS in human subjects and animal models of obesity...
December 2017: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/29333341/preventive-effects-of-salvia-officinalis-leaf-extract-on-insulin-resistance-and-inflammation-in-a-model-of-high-fat-diet-induced-obesity-in-mice-that-responds-to-rosiglitazone
#2
Mohamed R Ben Khedher, Mohamed Hammami, Jonathan R S Arch, David C Hislop, Dominic Eze, Edward T Wargent, Małgorzata A Kępczyńska, Mohamed S Zaibi
Background: Salvia officinalis (sage) is a native plant to the Mediterranean region and has been used for a long time in traditional medicine for various diseases. We investigated possible anti-diabetic, anti-inflammatory and anti-obesity effects of sage methanol (MetOH) extract in a nutritional mouse model of obesity, inflammation and insulin resistance, as well as its effects on lipolysis and lipogenesis in 3T3-L1 cells. Methods: Diet-induced obese (DIO) mice were treated for five weeks with sage methanol extract (100 and 400 mg kg-1/day bid), or rosiglitazone (3 mg kg-1/day bid), as a positive control...
2018: PeerJ
https://www.readbyqxmd.com/read/29328785/immune-responses-in-the-liver
#3
Paul Kubes, Craig Jenne
The liver is a key, frontline immune tissue. Ideally positioned to detect pathogens entering the body via the gut, the liver appears designed to detect, capture, and clear bacteria, viruses, and macromolecules. Containing the largest collection of phagocytic cells in the body, this organ is an important barrier between us and the outside world. Importantly, as portal blood also transports a large number of foreign but harmless molecules (e.g., food antigens), the liver's default immune status is anti-inflammatory or immunotolerant; however, under appropriate conditions, the liver is able to mount a rapid and robust immune response...
January 12, 2018: Annual Review of Immunology
https://www.readbyqxmd.com/read/29327746/silk-nanoparticles-from-inert-supports-to-bioactive-natural-carriers-for-drug-delivery
#4
REVIEW
Barbara Crivelli, Sara Perteghella, Elia Bari, Milena Sorrenti, Giuseppe Tripodo, Theodora Chlapanidas, Maria Luisa Torre
Silk proteins have been studied and employed for the production of drug delivery (nano)systems. They show excellent biocompatibility, controllable biodegradability and non-immunogenicity and, if needed, their properties can be modulated by blending with other polymers. Silk fibroin (SF), which forms the inner core of silk, is a (bio)material officially recognized by the Food and Drug Administration for human applications. Conversely, the potential of silk sericin (SS), which forms the external shell of silk, could still be considered under evaluation...
January 12, 2018: Soft Matter
https://www.readbyqxmd.com/read/29324644/nanocomposite-of-half-fin-anchovy-hydrolysates-zinc-oxide-nanoparticles-exhibits-actual-non-toxicity-and-regulates-intestinal-microbiota-short-chain-fatty-acids-production-and-oxidative-status-in-mice
#5
Ru Song, Jianbin Yao, Qingqing Shi, Rongbian Wei
The nanocomposite of half-fin anchovy hydrolysates (HAHp) and zinc oxide nanoparticles (ZnO NPs) (named as HAHp(3.0)/ZnO NPs) demonstrated increased antibacterial activity compared to either HAHp(3.0) or ZnO NPs as per our previous studies. Also, reactive oxygen species (ROS) formation was detected in Escherichia coli cells after treatment with HAHp(3.0)/ZnO NPs. The aim of the present study was to evaluate the acute toxicity of this nanocomposite and to investigate its effect on intestinal microbiota composition, short-chain fatty acids (SCFAs) production, and oxidative status in healthy mice...
January 11, 2018: Marine Drugs
https://www.readbyqxmd.com/read/29324075/screening-of-veterinary-drug-residues-in-food-by-lc-ms-ms-background-and-challenges
#6
Thierry Delatour, Lucie Racault, Thomas Bessaire, Aurélien Desmarchelier
Regulatory agencies and government authorities have established maximum residue limits (MRL) in various food matrices of animal origin for supporting governments and food operators in the monitoring of veterinary drug residues in the food chain, and ultimately in the consumer's plate. Today, about 200 veterinary drug residues from several families, mainly with antibiotic, antiparasitic or anti-inflammatory activities, are regulated in a variety of food matrices such as milk, meat or egg. The current article provides a review of the regulatory framework in milk and muscle including data from Codex Alimentarius, Europe, USA, Canada and China for about 220 veterinary drugs...
January 11, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29322620/rice-protein-matrix-enhances-circulating-levels-of-xanthohumol-following-acute-oral-intake-of-spent-hops-in-humans
#7
Annalouise O'Connor, Veera Konda, Ralph L Reed, J Mark Christensen, Jan F Stevens, Nikhat Contractor
SCOPE: Xanthohumol (XN), a prenylated flavonoid found in hops, exhibits anti-inflammatory and antioxidant properties. However, poor bioavailability may limit therapeutic applications. As food components are known to modulate polyphenol absorption, the objective was to determine whether a protein matrix could enhance the bioavailability of XN post oral consumption in humans. METHODS AND RESULTS: This was a randomized, double-blind, cross-over study in healthy participants (n = 6) evaluating XN and its major metabolites [isoxanthohumol (IX), 6- and 8-prenylnaringenin (6-PN, 8-PN)] for 6 hours following consumption of 12...
January 11, 2018: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/29319361/cinnamon-cinnamomum-zeylanicum-as-an-antidote-or-a-protective-agent-against-natural-or-chemical-toxicities-a-review
#8
Mahyar Dorri, Shirin Hashemitabar, Hossein Hosseinzadeh
Cinnamon (Cinnamomum zeylanicum, Lauraceae) is a food additive greatly used for its taste. However, recently this medicinal plant has been brought to attention due to its medical effects. Cinnamon has constituents such as cinnamaldehyde and cinnamic acid that offers some health benefits including antioxidant and free-radical scavenging properties, lowering of blood glucose, anti-cholesterolemic, analgesic, antimicrobial, anti-inflammatory, anti-yeast, anti-secretagogue, and anti-gastric ulcer effects. This review summarizes various in vitro and animal studies on the protective effects of cinnamon against natural and chemical toxins...
January 10, 2018: Drug and Chemical Toxicology
https://www.readbyqxmd.com/read/29305671/investigation-into-the-effects-of-tenilsetam-on-markers-of-neuroinflammation-in-gfap-il6-mice
#9
Erika Gyengesi, Huazheng Liang, Christopher Millington, Sandra Sonego, Daniel Sirijovski, Dhanushka Gunawardena, Karthik Dhananjayan, Madhuri Venigalla, Garry Niedermayer, Gerald Münch
PURPOSE: To test the short- and long-term effects of Tenilsetam on chronic neuroinflammation in the GFAP-IL6 mouse. METHODS: From 3 months of age, GFAP-IL6 mice were divided into 2 groups and fed with Tenilsetam enriched food pellets or control food pellets, respectively, for either 5 or 15 months. Total numbers of Iba-1+ microglia, TSPO+ cells were determined using an unbiased stereological method. Levels of methylglyoxal and TNF-α in the cerebellar homogenate were tested using HPLC and ELISA, respectively...
January 5, 2018: Pharmaceutical Research
https://www.readbyqxmd.com/read/29305434/modulation-of-the-il-33-il-13-axis-in-obesity-by-il-13r%C3%AE-2
#10
Jennifer Duffen, Melvin Zhang, Katherine Masek-Hammerman, Angela Nunez, Agnes Brennan, Jessica E C Jones, Jeffrey Morin, Karl Nocka, Marion Kasaian
In obesity, IL-13 overcomes insulin resistance by promoting anti-inflammatory macrophage differentiation in adipose tissue. Endogenous IL-13 levels can be modulated by the IL-13 decoy receptor, IL-13Rα2, which inactivates and depletes the cytokine. In this study, we show that IL-13Rα2 is markedly elevated in adipose tissues of obese mice. Mice deficient in IL-13Rα2 had high expression of IL-13 response markers in adipose tissue, consistent with increased IL-13 activity at baseline. Moreover, exposure to the type 2 cytokine-inducing alarmin, IL-33, enhanced serum and tissue IL-13 concentrations and elevated tissue eosinophils, macrophages, and type 2 innate lymphoid cells...
January 5, 2018: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/29302580/protective-effect-of-allium-tuberosum-extract-on-vascular-inflammation-in-tumor-necrosis-factor-%C3%AE-induced-human-vascular-endothelial-cells
#11
Haeng Jeon Hur, Ae Sin Lee
Background: Endothelial adhesion molecule expression induced by pro-inflammatory cytokine plays an important role in vascular endothelial cell injury, leading to vascular disease. Allium tuberosum (AT), which is used as a functional food, has a thrombolytic effect. It contains vitamin A, vitamin C, carbohydrate, calcium, iron, and phosphorus. There are many carotenes that turn into vitamin A in the body. Also, it helps blood circulation and stimulates metabolism. The purpose of the this study was to estimate the anti-inflammatory effects of the AT extract...
December 2017: Journal of Cancer Prevention
https://www.readbyqxmd.com/read/29301523/genoprotective-antioxidant-antifungal-and-anti-inflammatory-evaluation-of-hydroalcoholic-extract-of-wild-growing-juniperus-communis-l-cupressaceae-native-to-romanian-southern-sub-carpathian-hills
#12
Irina Fierascu, Camelia Ungureanu, Sorin Marius Avramescu, Carmen Cimpeanu, Mihaela Ioana Georgescu, Radu Claudiu Fierascu, Alina Ortan, Anca Nicoleta Sutan, Valentina Anuta, Anca Zanfirescu, Cristina Elena Dinu-Pirvu, Bruno Stefan Velescu
BACKGROUND: Juniperus communis L. represents a multi-purpose crop used in the pharmaceutical, food, and cosmetic industry. Several studies present the possible medicinal properties of different Juniperus taxa native to specific geographical area. The present study aims to evaluate the genoprotective, antioxidant, antifungal and anti-inflammatory potential of hydroalcoholic extract of wild-growing Juniperus communis L. (Cupressaceae) native to Romanian southern sub-Carpathian hills. METHODS: The prepared hydroethanolic extract of Juniperus communis L...
January 4, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29301119/cause-and-clinical-presentation-of-anaphylaxis-in-singapore-from-infancy-to-old-age
#13
Si Hui Goh, Jian Yi Soh, Wenyin Loh, Khai Pin Lee, Sze Chin Tan, Wei Jian Kenneth Heng, Irwani Ibrahim, Bee Wah Lee, Wen Chin Chiang
BACKGROUND: The study objective was to compare age-related differences in the cause and clinical presentation of anaphylaxis. METHODS: We conducted a prospective study of patients visiting the emergency department for anaphylaxis. Data were collected from 3 emergency departments from 1 April 2014 to 31 December 2015. Patient electronic records with the diagnoses of allergy, angioedema, urticaria, and anaphylaxis (ICD-9 codes 9953, 9951, 7080, 9950, 7089) were screened and cases fulfilling World Allergy Organisation criteria for anaphylaxis were included...
January 5, 2018: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29298969/-dietetary-recommendation-for-non-alcoholic-fatty-liver-disease
#14
REVIEW
Anna Jeznach-Steinhagen, Joanna Ostrowska, Aneta Czerwonogrodzka-Senczyna, Iwona Boniecka, Wioletta Gronostajska
Non-alcoholic Fatty Liver Disease (NAFLD) is currently the most common chronic liver disease in the developed world. Nowadays, in the adult population of Europe it is estimated at 14% to 21%. Its most important risk factors are obesity and metabolic syndrome. Introducing lifestyle changes such as: dietary intervention and increased physical activity are the first-line treatment and are intended to support not only NAFLD but also associated diseases such as obesity, insulin resistance, diabetes and dyslipidemia...
December 22, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29291429/curcumin-potentiates-cholesterol-lowering-effects-of-phytosterols-in-hypercholesterolaemic-individuals-a-randomised-controlled-trial
#15
Jessica J A Ferguson, Elizabeth Stojanovski, Lesley MacDonald-Wicks, Manohar L Garg
BACKGROUND: Dietary phytosterols (PS) are well-known hypocholesterolaemic agents. Curcumin elicits hypolipidaemic and anti-inflammatory effects in preclinical studies, however, consistent findings in humans are lacking. OBJECTIVE: Concurrent PS and curcumin supplementation may exhibit enhanced hypocholesterolaemic and anti-inflammatory effects to optimise cardio-protection. The objective of this trial was to investigate the effects of dietary intervention with PS with or without curcumin on blood lipids (primary outcome) in hypercholesterolaemic individuals...
December 29, 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29290061/effects-of-dissolved-organic-matter-feeding-and-water-flow-on-the-bioconcentration-of-diclofenac-in-crucian-carp-carassius-auratus
#16
Guanghua Lu, Zhengxin Xie, Zhenghua Zhang
Diclofenac (DCF), a prevalent anti-inflammatory drug, is frequently detected in aquatic organisms. However, little is known about the environmental factors that affect the bioconcentration of DCF in aquatic environments. Here, we firstly investigated the bioconcentration of DCF by crucian carp (Carassius auratus) following aqueous exposure (3.57, 14.5, and 71.8 μg L-1) for 21 days. DCF can accumulate in crucian carp, and the maximum bioconcentration factors (BCFs) of 121 L kg-1 in the liver, 52.3 L kg-1 in the gills, and 46...
December 30, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29287356/multifunctions-of-pleurotus-sajor-caju-fr-singer-a-highly-nutritious-food-and-a-source-for-bioactive-compounds
#17
Tiane C Finimundy, Lillian Barros, Ricardo C Calhelha, Maria José Alves, Miguel A Prieto, Rui M V Abreu, Aldo J P Dillon, João A P Henriques, Mariana Roesch-Ely, Isabel C F R Ferreira
A study with Pleurotus sajor-caju was conducted to: evaluate the nutritional and chemical composition of the fruiting bodies; optimize the preparation of bioactive phenolic extracts; and characterize the optimized extract in terms of bioactive compounds and properties. P. sajor-caju revealed an equilibrated nutritional composition with the presence of hydrophilic (sugars and organic acids) and lipophilic (tocopherols and PUFA) compounds. p-Hydroxybenzoic, p-coumaric and cinnamic acids were identified in the extract obtained with ethanol (30g/l ratio) at 55°C for 85min...
April 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29286348/plant-based-beverages-as-good-sources-of-free-and-glycosidic-plant-sterols
#18
Anneleen I Decloedt, Anita Van Landschoot, Hellen Watson, Dana Vanderputten, Lynn Vanhaecke
To address the ever-growing group of health-conscious consumers, more and more nutritional and health claims are being used on food products. Nevertheless, only very few food constituents, including plant sterols, have been appointed an approved health claim (European Commission and Food and Drugs Administration). Plant sterols are part of those limited lists of approved compounds for their cholesterol-lowering properties but have been praised for their anti-inflammatory and anti-carcinogenic properties as well...
December 29, 2017: Nutrients
https://www.readbyqxmd.com/read/29285925/yeast-%C3%AE-glucan-suppresses-the-chronic-inflammation-and-improves-the-microenvironment-in-adipose-tissues-of-ob-ob-mice
#19
Yan Cao, Ying Sun, Siwei Zou, Bingchao Duan, Mengying Sun, Xiaojuan Xu
Inflammation in visceral adipose tissues (VATs) contributes to the pathology of diabetes. This study focused on the inflammatory regulation in VATs by a yeast β-1,3-glucan (BYG) orally administered to ob/ob mice. BYG decreased pro-inflammatory modulators of TNF-α, IL-6, IL-1β, CCL2, and SAA3, and increased anti-inflammatory factors of Azgp1 (2.53±0.02 fold change) at protein and/or mRNA levels (p<0.05). Remarkably, BYG decreased the degree of adipose tissue macrophages (ATMs) infiltration to 82.5±8...
December 29, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29285096/anti-inflammatory-effect-of-delphinidin-on-intramedullary-spinal-pressure-in-a-spinal-cord-injury-rat-model
#20
Cheng-Hu Wang, Lin-Lin Zhu, Ke-Feng Ju, Jin-Long Liu, Kun-Peng Li
Delphinidin, a flavonoid polyphenolic compound, is widely found in nature and is used as a food supplement due to its pharmacological activity. The aims of the present study were to examine the anti-inflammatory effect of delphinidin in alleviating spinal cord injury (SCI)-induced inflammation in a rat model and to determine the underlying mechanisms in SCI. The Basso, Beattie, Bresnahan (BBB) scores of rats were assessed to evaluate the effect of delphinidin on the recovery of motor function. ELISA kits were also used to analyze the activities of tumor necrosis factor-α (TNF-α), interleukin (IL)-6, cyclooxygenase-2 (COX-2), prostaglandin E2 (PGE2) and caspase-3...
December 2017: Experimental and Therapeutic Medicine
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