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Anti-inflammatory food

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https://www.readbyqxmd.com/read/29786649/kudzu-leaf-extract-suppresses-the-production-of-inducible-nitric-oxide-synthase-cyclooxygenase-2-tumor-necrosis-factor-alpha-and-interleukin-6-via-inhibition-of-jnk-tbk1-and-stat1-in-inflammatory-macrophages
#1
Seok Hyun Eom, So-Jung Jin, Hee-Yeong Jeong, Youngju Song, You Jin Lim, Jong-In Kim, Youn-Hyung Lee, Hee Kang
Kudzu ( Pueraria montana var. lobata (Willd.) Sanjappa & Pradeep) is a perennial leguminous vine, and its root and flower have been used for herbal medicine in Asia for a long time. Most dietary flavonoids are reported to be concentrated in its root, not in its aerial parts including leaves. In this study, we investigated whether kudzu leaf and its major constituent, robinin (kaempferol-3- O -robinoside-7- O -rhanmoside) possessed anti-inflammatory activity. To test this hypothesis, we used peritoneal macrophages isolated from BALB/c mice and stimulated the cells with lipopolysaccharide (LPS) or LPS plus interferon (IFN)-γ...
May 22, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29785774/thymol-thyme-and-other-plant-sources-health-and-potential-uses
#2
REVIEW
Bahare Salehi, Abhay Prakash Mishra, Ila Shukla, Mehdi Sharifi-Rad, María Del Mar Contreras, Antonio Segura-Carretero, Hannane Fathi, Nafiseh Nasri Nasrabadi, Farzad Kobarfard, Javad Sharifi-Rad
Thymol is a naturally occurring phenol monoterpene derivative of cymene and isomer of carvacrol. Thymol (10-64%) is one of the major constituent of essential oils of thyme (Thymus vulgaris L., Lamiaceae), a medicinal plant with several therapeutic properties. This plant, native to Mediterranean regions, is commonly used as a culinary herb and also with a long history of use for different medicinal purposes. Nowadays, thymol and thyme present a wide range of functional possibilities in pharmacy, food, and cosmetic industry...
May 22, 2018: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29784301/two-new-farnesyl-phenolic-compounds-with-anti-inflammatory-activities-from-ganoderma-duripora
#3
Jie-Qing Liu, Chen-Lei Lian, Tian-Yong Hu, Cui-Fang Wang, Ying Xu, Lei Xiao, Zhi-Qiang Liu, Shu-Qi Qiu, Bao-Hui Cheng
Ganoderma fungi have long been used as a famous traditional medicine and food in country of East Asia. In this work, two new farnesyl phenolic compounds, ganoduriporols A and B (1 and 2), were isolated from the fruiting bodies of Ganoderma duripora, and their structures were elucidated using various spectroscopic methods. Anti-inflammatory activities were assayed and evaluated for the two compounds. Ganoduriporols A and B exhibited dose-dependent anti-inflammatory effects in RAW 264.7 cells. Furthermore, ganoduriporol A was demonstrated to inhibit the production of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), interleukin-6 (IL-6) and prostaglandin E2 (PGE2 ) through the suppression of COX-2, MAPK and NF-κB signaling pathway in LPS-induced macrophage cells...
October 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29783752/pro-apoptotic-and-anti-cancer-properties-of-diosgenin-a-comprehensive-and-critical-review
#4
REVIEW
Gautam Sethi, Muthu K Shanmugam, Sudha Warrier, Myriam Merarchi, Frank Arfuso, Alan Prem Kumar, Anupam Bishayee
Novel and alternative options are being adopted to combat the initiation and progression of human cancers. One of the approaches is the use of molecules isolated from traditional medicinal herbs, edible dietary plants and seeds that play a pivotal role in the prevention/treatment of cancer, either alone or in combination with existing chemotherapeutic agents. Compounds that modulate these oncogenic processes are potential candidates for cancer therapy and may eventually make it to clinical applications. Diosgenin is a naturally occurring steroidal sapogenin and is one of the major bioactive compounds found in dietary fenugreek ( Trigonella foenum-graecum ) seeds...
May 19, 2018: Nutrients
https://www.readbyqxmd.com/read/29775778/the-genus-cordyceps-an-extensive-review-of-its-traditional-uses-phytochemistry-and-pharmacology
#5
REVIEW
Opeyemi Joshua Olatunji, Jian Tang, Adesola Tola, Florence Auberon, Omolara Oluwaniyi, Zhen Ouyang
The genus Cordyceps has about 750 identified species which are distributed in many regions of the World, but mainly found in South Asia, Europe and North America. The species of the genus are highly priced and are widely used as food and medicine for the treatment of various ailments. This present review compiles literature information on the ethno-medicinal, phytochemistry and pharmacological properties of species in the genus Cordyceps. In addition, the review also suggest recommendations for the future researches...
May 15, 2018: Fitoterapia
https://www.readbyqxmd.com/read/29774057/ocrelizumab-a-new-milestone-in-multiple-sclerosis-therapy
#6
REVIEW
Patricia Mulero, Luciana Midaglia, Xavier Montalban
B cells play a central role in the pathogenesis of multiple sclerosis (MS): they are involved in the activation of pro-inflammatory T cells, secretion of pro-inflammatory cytokines and production of autoantibodies directed against myelin. Hence, the use of B cell-depleting monoclonal antibodies as therapy for autoimmune diseases, including MS, has increased in recent years. Previous results with rituximab, the first therapeutic B cell-depleting chimeric monoclonal antibody that showed efficacy in MS clinical trials, encouraged researchers to evaluate the efficacy of a humanized anti-CD20 antibody, ocrelizumab, in MS...
2018: Therapeutic Advances in Neurological Disorders
https://www.readbyqxmd.com/read/29773586/seafood-long-chain-n-3-polyunsaturated-fatty-acids-and-cardiovascular-disease-a-science-advisory-from-the-american-heart-association
#7
REVIEW
Eric B Rimm, Lawrence J Appel, Stephanie E Chiuve, Luc Djoussé, Mary B Engler, Penny M Kris-Etherton, Dariush Mozaffarian, David S Siscovick, Alice H Lichtenstein
Since the 2002 American Heart Association scientific statement "Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease," evidence from observational and experimental studies and from randomized controlled trials continues to emerge to further substantiate the beneficial effects of seafood long-chain n-3 polyunsaturated fatty acids and cardiovascular disease. A recent American Heart Association science advisory addressed the specific effect of n-3 polyunsaturated fatty acid supplementation on clinical cardiovascular events...
May 17, 2018: Circulation
https://www.readbyqxmd.com/read/29772529/microbial-bio-fuels-a-solution-to-carbon-emissions-and-energy-crisis
#8
Arun Kumar, Sumit Kaushal, Shubhini A Saraf, Jay Shankar Singh
Increasing energy demand, limited fossil fuel resources and climate change have prompted development of alternative sustainable and economical fuel resources such as crop-based bio-ethanol and bio-diesel. However, there is concern over use of arable land that is used for food agriculture for creation of biofuel. Thus, there is a renewed interest in the use of microbes particularly microalgae for bio-fuel production. Microbes such as micro-algae and cyanobacteria that are used for biofuel production also produce other bioactive compounds under stressed conditions...
June 1, 2018: Frontiers in Bioscience (Landmark Edition)
https://www.readbyqxmd.com/read/29771598/understanding-the-potential-benefits-of-thyme-and-their-derived-products-on-food-industry-and-health-from-extraction-of-high-added-value-compounds-to-the-evaluation-of-bioaccessibility-bioavailability-anti-inflammatory-and-antimicrobial-activities
#9
Jose M Lorenzo, Amin Mousavi Khaneghah, Mohsen Gavahian, Krystian Marszałek, Ismail Eş, Paulo E S Munekata, Isabel C F R Ferreira, Francisco J Barba
Natural bioactive compounds isolated from aromatic plants have been studied for centuries due to their unique characteristics that carry great importance in food, pharmaceutical, and cosmetic industry. For instance, several beneficial activities have been attributed to some specific compounds found in Thymus such as anti-inflammatory, antioxidant, antimicrobial and antiseptic properties. Moreover, these compounds are classified as Generally Recognized as Safe (GRAS). Conventional extraction processes of these compounds and their derived forms from thyme leaves are well established, however, they present some important drawbacks such as long extraction time, low yield, high solvent consumption and unfavorable effect on thermolabile compounds...
May 17, 2018: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29765456/indomethacin-induced-gastric-damage-in-rats-and-the-protective-effect-of-donkey-milk
#10
Ebru Tastekin, Suleyman Ayvaz, Ufuk Usta, Nurettin Aydogdu, Ekrem Cancilar, Fulya Oz Puyan
Introduction: Indomethacin is an anti-inflammatory drug with clearly known side effects on gastric mucosa. New treatment and side effect prevention methods are being studied. Donkey milk, as a nutritional support, has recently come into the spotlight with its anti-oxidant features, high antibody content and low allergenic properties. In this study, we investigated donkey milk's possible protective effect against acute gastric mucosal damage by indomethacin. Material and methods: Four groups, each composed of 8 rats, were created...
April 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29760610/the-structure-and-function-of-the-epidermal-barrier-in-patients-with-atopic-dermatitis-treatment-options-part-two
#11
REVIEW
Jagoda Pelc, Magdalena Czarnecka-Operacz, Zygmunt Adamski
Atopic dermatitis (AD) is a chronic and recurrent disease induced by underlying defects of the epidermal barrier and immunological disorders, typical of atopic diseases. The genetic and immunological mechanisms (outlined in the previous paper) affecting the dysfunction of the barrier are intensified by environmental factors, e.g. airborne and food allergens, infections and stress. For this reason, proper skin care, which prevents further damage and restores the epidermal barrier is of such importance in the field of AD therapy...
April 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29757557/-effects-of-ginkgo-biloba-extract-combined-with-glucocorticoid-on-olfactory-function-and-inflammatory-cytokines-in-mice-with-allergic-rhinitis
#12
Chan Wu, Yong Xiang Wei, Jayant Marian Pinto, Jun Tian, Xian Dao Yuan, Xiao Jun Zhan
Objective: To determine whether ginkgo biloba extract(GBE)combined with dexamethasone(DEX)plays a role in the treatment of allergic rhinitis-related olfactory dysfunction using an animal model. Method: Six week old BALB/C mice were sensitized and challenged with ovalbumin.30 sensitized mice were divided into three groups:Group 1 was given high-dose GBE and DEX(n=10);Group 2 was given low dose GBE and DEX(n=10);Group 3 was given DEX alone(n=10).We assessed the histology of the olfactory mucosa and serum IL-4,IFN-γ,and caspase 1...
January 20, 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29757247/enrichment-and-purification-of-total-ginkgo-flavonoid-o-glycosides-from-ginkgo-biloba-extract-with-macroporous-resin-and-evaluation-of-anti-inflammation-activities-in-vitro
#13
Lihu Zhang, Tingting Wu, Wei Xiao, Zhenzhong Wang, Gang Ding, Linguo Zhao
In the present study, the performance and separation characteristics of six macroporous resins for the enrichment and purification of total ginkgo flavonoid O -glycosides (TGFs) (quercetin (I), kaempferol (II), isorhamnetin (III)) from Ginkgo Biloba extracts (EGB) are evaluated. The adsorption and desorption properties of TGFs are studied on macroporous resins, including D101, D201, AB-8, HPD400, D301, and D311. Along with the results, AB-8 resin exhibits the best adsorption and desorption capacity for these three ginkgo flavonoid O -glycosides among the six resins...
May 13, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29756573/lactoferrin-major-physiological-functions-and-applications
#14
Liyuan Hao, Qiang Shan, Jingya Wei, Fengtao Ma, Peng Sun
Lactoferrin (lactotransferrin; Lf) is an iron-binding glycoprotein and one of the most important bioactivators in milk and other external secretions. It has numerous biological roles, including the regulation of iron absorption and modulation of immune responses, and has anti-microbial, anti-viral, antioxidant, anti-cancer, and anti-inflammatory activities. Lf regulates the quantity of iron absorbed in the intestine via its role in iron transport and can also chelate iron, directly or indirectly. Notably, it has been used as an adjuvant therapy for some intestinal diseases...
May 14, 2018: Current Protein & Peptide Science
https://www.readbyqxmd.com/read/29754829/randomization-to-6-month-mediterranean-diet-compared-with-a-low-fat-diet-leads-to-improvement-in-dietary-inflammatory-index-scores-in-patients-with-coronary-heart-disease-the-ausmed-heart-trial
#15
Hannah L Mayr, Colleen J Thomas, Audrey C Tierney, Teagan Kucianski, Elena S George, Miguel Ruiz-Canela, James R Hebert, Nitin Shivappa, Catherine Itsiopoulos
A higher dietary inflammatory index (DII®) score is associated with inflammation and incidence of coronary heart disease (CHD). We hypothesized that a Mediterranean diet (MedDiet) intervention would reduce DII score. We assessed dietary data from a randomized controlled trial comparing 6-month MedDiet versus low-fat diet intervention, in patients with CHD. We aimed to determine the DII scores of the prescribed diets' model meal plans, followed by whether dietary intervention led to lower (i.e., more anti-inflammatory) DII scores and consequently lower high sensitivity C-reactive protein (hs-CRP) and interleukin-6 (hs-IL-6)...
April 14, 2018: Nutrition Research
https://www.readbyqxmd.com/read/29754250/estimated-daily-quercetin-intake-and-association-with-the-prevalence-of-type-2-diabetes-mellitus-in-chinese-adults
#16
Zhanxin Yao, Yeqing Gu, Qing Zhang, Li Liu, Ge Meng, Hongmei Wu, Yang Xia, Xue Bao, Hongbin Shi, Shaomei Sun, Xing Wang, Ming Zhou, Qiyu Jia, Yuntang Wu, Kun Song, Weina Gao, Changjiang Guo, Kaijun Niu
PURPOSE: Quercetin is one of potential antidiabetic substances because of its powerful antioxidant and anti-inflammatory actions. The purpose of this study is to estimate daily quercetin intake and assess the relationship between dietary quercetin intake and the prevalence of type 2 diabetes mellitus (T2DM) in a Chinese population. METHODS: Dietary intake was investigated by a validated 100-item food frequency questionnaire. Daily intakes of quercetin and nutrients were calculated accordingly...
May 12, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29751683/a-new-venue-of-tnf-targeting
#17
REVIEW
Sophie Steeland, Claude Libert, Roosmarijn E Vandenbroucke
The first Food and Drug Administration-(FDA)-approved drugs were small, chemically-manufactured and highly active molecules with possible off-target effects, followed by protein-based medicines such as antibodies. Conventional antibodies bind a specific protein and are becoming increasingly important in the therapeutic landscape. A very prominent class of biologicals are the anti-tumor necrosis factor (TNF) drugs that are applied in several inflammatory diseases that are characterized by dysregulated TNF levels...
May 11, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29750772/the-ins-and-outs-of-an-outside-in-view-of-allergies-atopic-dermatitis-and-allergy-prevention
#18
Marcus Shaker, Robert G P Murray, Julianne A Mann
PURPOSE OF REVIEW: The skin barrier is a dynamic innate immune organ. This review summarizes the current understanding of how deficiencies associated with atopic dermatitis invite other atopic disorders of the allergic march. RECENT FINDINGS: Atopic dermatitis is characterized by skin barrier defects (such as mutations in filaggrin), intrinsic proallergic T-helper cell 2 immune dysregulation, and skin microbiome alterations. These factors promote the development of food allergy and asthma...
May 9, 2018: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/29747750/crocus-sativus-a-natural-food-coloring-and-flavoring-has-potent-anti-tumor-properties
#19
REVIEW
Zahra Khorasanchi, Mojtaba Shafiee, Farnoush Kermanshahi, Majid Khazaei, Mikhail Ryzhikov, Mohammad Reza Parizadeh, Behnoush Kermanshahi, Gordon A Ferns, Amir Avan, Seyed Mahdi Hassanian
BACKGROUND: Saffron, the dried stigmas of Crocus sativus L., is a highly valued agricultural product that is used mainly as a food coloring and flavoring agent. Three main secondary metabolites of Crocus sativus including crocin, picrocrocin, and safranal are responsible for the color, the bitter taste and for the odor and aroma, respectively. As a component of traditional medicine, saffron has been utilized as a medicinal herb for treating various ailments including cramps, asthma, liver disease, menstruation disorders, pain, and in the pathogenesis of cancer...
April 1, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29747410/production-and-bioactivity-guided-isolation-of-antioxidants-with-%C3%AE-glucosidase-inhibitory-and-anti-no-properties-from-marine-chitinous-materials
#20
Van Bon Nguyen, Thi Hanh Nguyen, Chien Thang Doan, Thi Ngoc Tran, Anh Dzung Nguyen, Yao-Haur Kuo, San-Lang Wang
Natural and bioactive products have been of great interest due to their benefit as health foods and drugs to prevent various diseases. The aim of this study is to efficiently reuse marine chitinous materials (CMs), abundant and low-cost fishery by-products, for the bio-synthesis, isolation, and identification of antioxidant compounds possessing some other beneficial bioactivities. Paenibacillus sp. was used to convert CMs to antioxidants. Among various tested CMs, squid pen powder (SPP) gave the best results when used as the sole carbon/nitrogen source...
May 9, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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