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Medial meniscus

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https://www.readbyqxmd.com/read/29349991/-effects-of-creating-a-tunnel-through-intercondylar-fossa-under-arthroscopy-for-the-treatment-of-complex-tears-at-the-medial-meniscus-posterior-horn
#1
Ling-Dai Dong, Chang-Jian Bing, Jian-Lin Li, Yue Cai
OBJECTIVE: To discuss the advantages of the arthroscopic treatment for complex tears of the medial meniscus posterior horn by creating a tunnel passageway through the intercondylar fossa. METHODS: All 127 patients including 24 males and 103 females with complex tears at the medial meniscus posterior horn were reviewed. The age of all patients ranged from 45 to 78 years old, with an average of 67 years old. All 127 patients were treated with partial meniscectomy, in which 112 patients were treated with partial meniscectomy smoothly with three incisions (anterior medial incision, anterior lateral incision, high anterior lateral incision), and 15 patients were treated with four incisions (anterior medial incision, anterior lateral incision, high anterior lateral incision, posterior medial incision)...
April 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29349977/-therapeutic-effects-of-internal-drainage-by-expanding-arthroscopic-gastrocnemius-semimembranosus-bursa-and-cyst-wall-resection-for-the-treatment-of-41-patients-with-popliteal-cysts
#2
Li-Chuang Wu, Hai-Bo Zhou, Chao Zhang, Lei Chen, Cai-Long Liu
OBJECTIVE: To investigate the clinical curative effects of internal drainage by expanding arthroscopic gastrocnemius-semimembranosus bursa(GSB) and cyst wall resection for the treatment of popliteal cysts. METHODS: A retrospective analysis of patients from May 2011 to December 2015. Arthroscopic treatment for 41 patients with popliteal fossa cysts, 18 males and 23 females, aged from 34 to 67 years old, averaged 42.6 years old. All the patients had preoperative magnetic resonance imagings to confirm the diagnosis and identify the valvular opening(Gastrocnemius-Semimembranosus bursa, GSB), as well as the associated intra-articular pathology...
April 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29333118/the-relationship-between-chondromalacia-patella-medial-meniscal-tear-and-medial-periarticular-bursitis-in-patients-with-osteoarthritis
#3
Mustafa Resorlu, Davut Doner, Ozan Karatag, Canan Akgun Toprak
Background: This study investigated the presence of bursitis in the medial compartment of the knee (pes anserine, semimembranosus-tibial collateral ligament, and medial collateral ligament bursa) in osteoarthritis, chondromalacia patella and medial meniscal tears. Patients and methods: Radiological findings of 100 patients undergoing magnetic resonance imaging with a preliminary diagnosis of knee pain were retrospectively evaluated by two radiologists. The first radiologist assessed all patients in terms of osteoarthritis, chondromalacia patella and medial meniscal tear...
December 2017: Radiology and Oncology
https://www.readbyqxmd.com/read/29329496/positive-feedback-regulation-of-subchondral-h-type-vessel-formation-by-chondrocyte-promotes-osteoarthritis-development-in-mice
#4
Jiansen Lu, Haiyan Zhang, Daozhang Cai, Chun Zeng, Pinglin Lai, Yan Shao, Hang Fang, Delong Li, Jiayao Ouyang, Chang Zhao, Denghui Xie, Bin Huang, Jian Yang, Yu Jiang, Xiaochun Bai
Vascular-invasion-mediated interactions between activated articular chondrocytes and subchondral bone are essential for osteoarthritis (OA) development. Here, we determined the role of nutrient sensing mechanistic target of rapamycin complex 1 (mTORC1) signaling in the crosstalk across the bone cartilage interface and its regulatory mechanisms. Then mice with chondrocyte-specific mTORC1 activation (Tsc1 CKO and Tsc1 CKOER ) or inhibition (Raptor CKOER ) and their littermate controls were subjected to OA induced by destabilization of the medial meniscus (DMM) or not...
January 12, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29323710/blocking-pi3k-akt-signaling-inhibits-bone-sclerosis-in-subchondral-bone-and-attenuates-post-traumatic-osteoarthritis
#5
Chuangxin Lin, Yan Shao, Chun Zeng, Chang Zhao, Hang Fang, Liping Wang, Jianying Pan, Liangliang Liu, Weizhong Qi, Xiaofeng Feng, Hong Qiu, Haiyang Zhang, Yuhui Chen, Hong Wang, Daozhang Cai, Cory J Xian
PI3K/AKT signaling is essential in regulating pathophysiology of osteoarthritis (OA). However, its potential modulatory role in early OA progression has not been investigated yet. Here, a mouse destabilization OA model in the tibia was used to investigate roles of PI3K/AKT signaling in the early subchondral bone changes and OA pathological process. We revealed a significant increase in PI3K/AKT signaling activation which was associated with aberrant bone formation in tibial subchondral bone following destabilizing the medial meniscus (DMM), which was effectively prevented by treatment with PI3K/AKT signaling inhibitor LY294002...
January 11, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29314864/outcomes-of-osteochondral-allograft-transplantation-with-and-without-concomitant-meniscus-allograft-transplantation-a-comparative-matched-group-analysis
#6
Rachel M Frank, Simon Lee, Eric J Cotter, Charles P Hannon, Timothy Leroux, Brian J Cole
BACKGROUND: Osteochondral allograft transplantation (OCA) is often performed with concomitant meniscus allograft transplantation (MAT) as a strategy for knee joint preservation, although to date, the effect of concomitant MAT on outcomes and failure rates after OCA has not been assessed. PURPOSE: To determine clinical outcomes for patients undergoing OCA with MAT as compared with a matched cohort of patients undergoing isolated OCA. STUDY DESIGN: Control study; Level of evidence, 3...
January 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29314205/cdc42-is-essential-for-both-articular-cartilage-degeneration-and-subchondral-bone-deterioration-in-experimental-osteoarthritis
#7
Xinhua Hu, Xing Ji, Mengting Yang, Shihao Fan, Jirong Wang, Meiping Lu, Wei Shi, Liu Mei, Chengyun Xu, Xueying Fan, Musaddique Hussain, Jingyu Du, Junsong Wu, Ximei Wu
Cdc42, a member of Rho family small GTPases, is critical for cartilage development. We investigated the roles of Cdc42 in osteoarthritis and explored the potential mechanism underlying Cdc42-mediated articular cartilage degeneration and subchondral bone deterioration. Cdc42 is highly expressed in both articular cartilage and subchondral bone in a mouse osteoarthritis model with surgical destabilisation of the medial meniscus (DMM) in the knee joints. Specifically, genetic disruption of Cdc42, knockdown of Cdc42 expression, or inhibition of Cdc42 activity robustly attenuates the DMM-induced destruction, hypertrophy, high expression of matrix metallopeptidase-13 and collagen X, and activation of Stat3 in articular cartilages...
January 3, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29309717/bucket-handle-tear-of-the-medial-meniscus-in-a-2-year-old-child
#8
Kyle Fink, Neil Kaushal, Jordan Gross, Himanshu Patel, Damon Delbello
Bucket-handle meniscal tears are extremely rare injuries in the pediatric population. Given the known sequelae of meniscal tears and the development of osteoarthritis, early diagnosis and treatment of pediatric meniscal tears are essential. The communication barrier between physicians and pediatric patients, however, creates difficulties in making the correct diagnosis of meniscal pathology. Providers should have a low threshold for obtaining further confirmatory advanced imaging if patients present with prolonged knee pain and swelling, with associated locking mechanical symptoms...
January 8, 2018: Orthopedics
https://www.readbyqxmd.com/read/29305427/patient-specific-medial-unicompartmental-knee-arthroplasty-has-a-greater-protective-effect-on-articular-cartilage-in-the-lateral-compartment-a-finite-element-analysis
#9
K-T Kang, J Son, D-S Suh, S K Kwon, O-R Kwon, Y-G Koh
OBJECTIVES: Patient-specific (PS) implantation surgical technology has been introduced in recent years and a gradual increase in the associated number of surgical cases has been observed. PS technology uses a patient's own geometry in designing a medical device to provide minimal bone resection with improvement in the prosthetic bone coverage. However, whether PS unicompartmental knee arthroplasty (UKA) provides a better biomechanical effect than standard off-the-shelf prostheses for UKA has not yet been determined, and still remains controversial in both biomechanical and clinical fields...
January 2018: Bone & Joint Research
https://www.readbyqxmd.com/read/29285587/the-percutaneous-pie-crusting-medial-release-during-arthroscopic-procedures-of-the-medial-meniscus-does-neither-affect-valgus-laxity-nor-clinical-outcome
#10
Sang-Woo Jeon, Min Jung, Yong-Min Chun, Su-Keon Lee, Woo Seok Jung, Chong Hyuk Choi, Sung-Jae Kim, Sung-Hwan Kim
PURPOSE: To analyze the effect of percutaneous pie-crusting medial release on valgus laxity before and after surgery and on clinical outcomes. METHODS: Eight-hundred fourteen consecutive patients who underwent an arthroscopic procedure for the medial compartment of the knee were evaluated retrospectively. Sex, age, type of operation (meniscectomy, meniscal repair, and posterior root repair), type of accompanying surgery (none, cartilage procedure, ligament procedure and osteotomy) were documented...
December 28, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29275548/optical-spectroscopic-characterization-of-human-meniscus-biomechanical-properties
#11
Juho Ala-Myllymäki, Elvis K Danso, Juuso T J Honkanen, Rami K Korhonen, Juha Töyräs, Isaac O Afara
This study investigates the capacity of optical spectroscopy in the visible (VIS) and near-infrared (NIR) spectral ranges for estimating the biomechanical properties of human meniscus. Seventy-two samples obtained from the anterior, central, and posterior locations of the medial and lateral menisci of 12 human cadaver joints were used. The samples were subjected to mechanical indentation, then traditional biomechanical parameters (equilibrium and dynamic moduli) were calculated. In addition, strain-dependent fibril network modulus and permeability strain-dependency coefficient were determined via finite-element modeling...
December 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/29260438/novel-flat-and-wide-meniscal-repair-material-improves-the-ultimate-load-of-knot-breakage-in-a-porcine-trans-capsular-meniscal-repair-model
#12
Hiroyuki Yokoi, Tatsuo Mae, Ryo Iuchi, Yasuhiro Take, Yuta Tachibana, Kazunori Shimomura, Tomoki Ohori, Konsei Shino, Hideki Yoshikawa, Ken Nakata
BACKGROUND: In the meniscal repair procedures, a high ultimate load capacity and low cyclic creep at the repair site are favorable and lead to good biological incorporation of the tear site after surgery. Previous biomechanical tensile tests of the meniscal sutures have identified the suture knot as the weakest point. We hypothesized that the strength of a suture knot depends on the suture shape, and therefore, we compared three differently shaped suture materials composed of the same material and quantity per length...
December 19, 2017: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/29244532/risk-factors-and-predictors-of-significant-chondral-surface-change-from-primary-to-revision-anterior-cruciate-ligament-reconstruction-a-moon-and-mars-cohort-study
#13
Robert A Magnussen, James R Borchers, Angela D Pedroza, Laura J Huston, Amanda K Haas, Kurt P Spindler, Rick W Wright, Christopher C Kaeding, Christina R Allen, Allen F Anderson, Daniel E Cooper, Thomas M DeBerardino, Warren R Dunn, Brett A Lantz, Barton Mann, Michael J Stuart, John P Albright, Annunziato Amendola, Jack T Andrish, Christopher C Annunziata, Robert A Arciero, Bernard R Bach, Champ L Baker, Arthur R Bartolozzi, Keith M Baumgarten, Jeffery R Bechler, Jeffrey H Berg, Geoffrey A Bernas, Stephen F Brockmeier, Robert H Brophy, Charles A Bush-Joseph, J Brad Butler, John D Campbell, James L Carey, James E Carpenter, Brian J Cole, Jonathan M Cooper, Charles L Cox, R Alexander Creighton, Diane L Dahm, Tal S David, David C Flanigan, Robert W Frederick, Theodore J Ganley, Elizabeth A Garofoli, Charles J Gatt, Steven R Gecha, James Robert Giffin, Sharon L Hame, Jo A Hannafin, Christopher D Harner, Norman Lindsay Harris, Keith S Hechtman, Elliott B Hershman, Rudolf G Hoellrich, Timothy M Hosea, David C Johnson, Timothy S Johnson, Morgan H Jones, Ganesh V Kamath, Thomas E Klootwyk, Bruce A Levy, C Benjamin Ma, G Peter Maiers, Robert G Marx, Matthew J Matava, Gregory M Mathien, David R McAllister, Eric C McCarty, Robert G McCormack, Bruce S Miller, Carl W Nissen, Daniel F O'Neill, Brett D Owens, Richard D Parker, Mark L Purnell, Arun J Ramappa, Michael A Rauh, Arthur C Rettig, Jon K Sekiya, Kevin G Shea, Orrin H Sherman, James R Slauterbeck, Matthew V Smith, Jeffrey T Spang, Steven J Svoboda, Timothy N Taft, Joachim J Tenuta, Edwin M Tingstad, Armando F Vidal, Darius G Viskontas, Richard A White, James S Williams, Michelle L Wolcott, Brian R Wolf, James J York
BACKGROUND: Articular cartilage health is an important issue following anterior cruciate ligament (ACL) injury and primary ACL reconstruction. Factors present at the time of primary ACL reconstruction may influence the subsequent progression of articular cartilage damage. HYPOTHESIS: Larger meniscus resection at primary ACL reconstruction, increased patient age, and increased body mass index (BMI) are associated with increased odds of worsened articular cartilage damage at the time of revision ACL reconstruction...
December 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29244223/fixed-bearing-medial-unicompartmental-knee-arthroplasty-restores-neither-the-medial-pivoting-behavior-nor-the-ligament-forces-of-the-intact-knee-in-passive-flexion
#14
Mohammad Kia, Lucian C Warth, Joseph D Lipman, Timothy M Wright, Geoffrey H Westrich, Michael B Cross, David J Mayman, Andrew D Pearle, Carl W Imhauser
Medial unicompartmental knee arthroplasty (UKA) is an accepted treatment for isolated medial osteoarthritis. However, using an improper thickness for the tibial component may contribute to early failure of the prosthesis or disease progression in the unreplaced lateral compartment. Little is known of the effect of insert thickness on both knee kinematics and ligament forces. Therefore, a computational model of the tibiofemoral joint was used to determine how non-conforming, fixed bearing medial UKA affects tibiofemoral kinematics and tension in the medial collateral ligament (MCL) and the anterior cruciate ligament (ACL) during passive knee flexion...
December 15, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29225019/primary-versus-revision-anterior-cruciate-ligament-reconstruction-patient-demographics-radiographic-findings-and-associated-lesions
#15
Justin J Mitchell, Mark E Cinque, Grant J Dornan, Lauren M Matheny, Chase S Dean, Brad Kruckeberg, Gilbert Moatshe, Jorge Chahla, Robert F LaPrade
PURPOSE: The purpose of this study was to evaluate the differences in intra-articular pathology, demographic characteristics, and radiographic characteristics of the knee associated with primary anterior cruciate ligament reconstruction (ACLR) versus revision ACLR at the time of initial presentation with either a native anterior cruciate ligament tear or an anterior cruciate ligament graft tear. Secondarily, we aimed to investigate risk factors for concomitant medial and lateral meniscal tears and cartilage injuries at the time of ACLR...
December 7, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29209793/degenerative-changes-after-posterior-cruciate-ligament-reconstruction-are-irrespective-of-posterior-knee-stability-mri-based-long-term-results
#16
Clemens Gwinner, Andreas Weiler, Timm Denecke, Julian M M Rogasch, Heide Boeth, Tobias M Jung
INTRODUCTION: Posterior cruciate ligament reconstruction (PCLR) is advocated to prevent an early onset of osteoarthritis. We hypothesized that posterior instability after PCLR correlates with degenerative changes. MATERIALS AND METHODS: MRIs of 42 (12 female/30 male; 39 ± 9 years) patients were enrolled with a minimum 5-year follow-up (FFU) after PCLR. In addition, 25 contralateral and 15 follow-up MRIs (12 months after baseline) were performed. Degenerative changes were graded using WORMS...
December 6, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29207986/risk-of-total-subtotal-meniscectomy-for-respective-medial-and-lateral-meniscus-injury-correlation-with-tear-type-duration-of-complaint-age-gender-and-acl-rupture-in-6034-asian-patients
#17
Dong Jiang, Xiao Luo, Yingfang Ao, Xi Gong, Yong-Jian Wang, Hai-Jun Wang, Yu Miao, Nan Li, Ji-Ying Zhang, Jia-Kuo Yu
BACKGROUND: To evaluate the risk factor associated with total or subtotal meniscectomy for respective medial and lateral meniscus injury. METHODS: The data of all the meniscus injured patients undergoing arthroscopy in our institute between January 15th, 2000 and December 31st, 2008 was collected and 6034 patients with 7241 injured menisci met the inclusion criteria. The mean patient age was 33.6 ± 14.9 years and there were 4785 males and 2456 females with 3568 medial and 3673 lateral menisci...
December 5, 2017: BMC Surgery
https://www.readbyqxmd.com/read/29202561/meniscal-extrusion-as-booster-of-osteoarthritis
#18
R Papalia, G Papalia, F Russo, L A Diaz, F Bressi, S Sterzi, V Denaro
Meniscal extrusion (ME) has shown to play a critical but still unclear role in osteoarthritis (OA) development. ME has been described as an important risk factor in the progression of knee OA, as it is involved in the thinning of articular cartilage, joint space narrowing, spontaneous osteonecrosis of the knee and subchondral bone marrow lesions. Meniscal damage of any degree of severity could cause ME in both compartments, but it is commonly associated with severe meniscal tears or root tears mainly in the medial meniscus...
December 4, 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29198047/medial-meniscus-grafting-restores-normal-tibiofemoral-contact-pressures
#19
John Nyland, Kirk Campbell, Alaa Kalloub, Eric J Strauss, Katrina Kuban, David N M Caborn
BACKGROUND: Tissue excision in the setting of a meniscal tear has been shown to dramatically increase peak contact stresses in the affected tibiofemoral joint compartment, leading to the development of degenerative changes and osteoarthritis. PURPOSE/HYPOTHESIS: The current in vitro study utilized a porcine model to evaluate the effectiveness of segmental medial meniscal grafting following partial meniscectomy. The study hypothesis was that the procedure would normalize medial tibofemoral joint compartment pressure magnitudes, areas, and locations relative to an intact meniscus...
December 2, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29193888/associations-between-slower-walking-speed-and-t1%C3%AF-magnetic-resonance-imaging-of-femoral-cartilage-following-anterior-cruciate-ligament-reconstruction
#20
Steven Pfeiffer, Matthew S Harkey, Laura E Stanley, J Troy Blackburn, Darin A Padua, Jeffrey T Spang, Stephen W Marshall, Joanne M Jordan, Randy Schmitz, Daniel Nissman, Brian Pietrosimone
To determine if walking speed collected at 6 and 12 months following anterior cruciate ligament reconstruction (ACLR) associates with inter-limb differences in proteoglycan density, measured via T1ρ magnetic resonance imaging (MRI), in tibiofemoral articular cartilage 12 months following ACLR METHODS: Twenty-one individuals with a unilateral patellar-tendon autograft ACLR (10 females, 11 males, 23.9±2.7 years, 23.9±2.7 BMI) were recruited for participation in this study. Walking speed was collected using 3-dimensional motion capture at 6 and 12 months following ACLR...
November 28, 2017: Arthritis Care & Research
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