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https://www.readbyqxmd.com/read/27915339/clinicopathological-features-and-predictive-factors-for-colorectal-cancer-outcome-in-the-kingdom-of-saudi-arabia
#1
Abdurrahman Aldiab, Khayal A Al Khayal, Omar A Al Obaid, Ahmed Alsheikh, Khalid Alsaleh, Mohamed Shahid, Hana Alkharji
BACKGROUND/AIMS: Colorectal cancer (CRC) is the most frequent cancer and a leading cause of cancer death in the Kingdom of Saudi Arabia (KSA). To date, no nationwide screening programs have been adopted. This prospective, longitudinal study investigated factors influencing the outcome of CRC in Saudi patients. METHODS: Patients completed a CRC awareness questionnaire. Colonoscopy, CT/MRI, histopathology of tumor biopsies, and KRAS and BRAF testing were performed...
December 3, 2016: Oncology
https://www.readbyqxmd.com/read/27913912/genetic-counselor-practices-involving-pediatric-patients-with-fap-an-investigation-of-their-self-reported-strategies-for-genetic-testing-and-hepatoblastoma-screening
#2
Caitlin E Lawson, Thomas M Attard, Hongying Dai, Seth Septer
Familial adenomatous polyposis (FAP) is a cancer predisposition syndrome that causes early-onset polyposis and is associated with an increased risk for hepatoblastoma. There is currently a lack of consensus on when to order APC (adenomatous polyposis coli) gene testing or implement surveillance for hepatoblastoma. An online questionnaire was completed by 62 genetic counselors to capture their current practices regarding these questions. Extracolonic findings associated with FAP that were most likely to prompt APC testing in an otherwise asymptomatic 10 year-old child with a negative family history were multiple desmoid tumors, congenital hypertrophy of the retinal pigment epithelium (CHRPE), jaw osteomas, and hepatoblastoma...
December 3, 2016: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/27892965/diabetes-mellitus-and-risk-of-colorectal-cancer-mortality-in-japan-the-japan-collaborative-cohort-study
#3
Ce Tan, Mitsuru Mori, Yasushi Adachi, Kenji Wakai, Sadao Suzuki, Koji Suzuki, Shuji Hashimoto, Yoshiyuki Watanabe, Akiko Tamakoshi
Objective: Our aim was to estimate whether diabetes mellitus (DM) may be associated with an increased risk of colorectal cancer (CRC) mortality in Japan. Methods: The Japan Collaborative Cohort (JACC) Study is a nationwide prospective study, initiated in 1988, which involves 110,585 subjects (age range: from 40 to 79 years; 46,395 males and 64,190 females). Our present analysis population comprised 96,081 (40,510 men and 55,571 women) who provided details on DM history. The questionnaire also included age, sex, weight, height, family history of CRC, smoking, drinking and exercise habits, and education...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27861761/prediagnostic-alcohol-consumption-and-colorectal-cancer-survival-the-colon-cancer-family-registry
#4
Amanda I Phipps, Jamaica R Robinson, Peter T Campbell, Aung Ko Win, Jane C Figueiredo, Noralane M Lindor, Polly A Newcomb
BACKGROUND: Although previous studies have noted an increased risk of colorectal cancer (CRC) among moderate to heavy alcohol consumers in comparison with nondrinkers, the relation between alcohol consumption and CRC survival remains unclear. METHODS: Cases of incident invasive CRC diagnosed between 1997 and 2007 were identified via population-based cancer registries at 4 study sites in the Colon Cancer Family Registry. Study participants completed a risk-factor questionnaire on prediagnostic behaviors, including wine, beer, and liquor consumption, at the baseline...
November 8, 2016: Cancer
https://www.readbyqxmd.com/read/27814821/direct-interactive-public-education-by-breast-radiologists-about-screening-mammography-impact-on-anxiety-and%C3%A2-empowerment
#5
Jiyon Lee, Lara A Hardesty, Nathan M Kunzler, Andrew B Rosenkrantz
PURPOSE: Anxiety has been called a "harm" of screening mammography. The authors provided direct, interactive education to lay audiences and measured these sessions' impact on anxiety and any increased understanding of breast cancer screening. METHODS: Academic breast radiologist provided seven 1-hour sessions of structured lectures and question-and-answer periods. Lay language and radiologic images were used to discuss disease background, screening guidelines, and areas of debate...
November 2016: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/27797256/relationships-of-fear-of-breast-cancer-and-fatalism-with-screening-behavior-in-women-referred-to-health-centers-of-tabriz-in-iran
#6
Akram Ghahramanian, Azad Rahmani, Ahmad Mirza Aghazadeh, Lida Emami Mehr
BACKGROUND: Fear and fatalism have been proposed as factors affecting breast cancer screening, but the evidence is not strong. This study aimed to determine relationships of fear and fatalism with breast cancer screening behavior among Tabriz women in Iran. MATERIALS AND METHODS: In a cross- sectional study, 370 women referred to 12 health centers in Tabriz were selected with two-stage cluster sampling and data regarding breast cancer screening, fatalism and fear of breast cancer were collected respectively with a checklist for screening performance, Champions Fear and Pow Fatalism Questionnaires...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27794394/who-should-be-checked-for-hepatitis-c-virus-infection-in-endemic-areas
#7
Wattana Sukeepaisalncharoen, Udomlack Peansukwech, Kittisak Sawanyawisuth
OBJECTIVE: To find additional factors suggestive of hepatitis C virus (HCV) infection in the general population by using data from a hepatitis virus survey. METHODS: This study collected data of HCV infection from a hepatitis virus survey. The survey was conducted in 13 provinces in the northeast Thailand in 2014 and 2015. During the survey, a blood test was performed to screen for HCV. A questionnaire was also distributed to all participants asking about baseline characteristics, risk factors for HCV infection, and daily life activities...
October 2016: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/27794170/association-between-the-dietary-inflammatory-index-and-breast-cancer-in-a-large-italian-case-control-study
#8
Nitin Shivappa, James R Hébert, Valentina Rosato, Maurizio Montella, Diego Serraino, Carlo La Vecchia
INTRODUCTION: The putative relationship between diet, including its inflammatory potential, and breast cancer has been studied extensively, but results remain inconsistent. Using data from a large Italian case-control study conducted between 1991 and 1994, we examined the association between the dietary inflammatory index (DII) and odds of breast cancer. METHODS: DII scores were computed using a validated 78-item food frequency questionnaire. Subjects were 2569 women with incident, histologically confirmed breast cancer and 2588 controls admitted to hospital for acute, non-hormone-related diseases...
October 29, 2016: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/27782199/risk-factors-for-sporadic-pancreatic-neuroendocrine-tumors-a-case-control-study
#9
Qiwen Ben, Jie Zhong, Jian Fei, Haitao Chen, Lifen Yv, Jihong Tan, Yaozong Yuan
The current study examined risk factors for sporadic pancreatic neuroendocrine tumors (PNETs), including smoking, alcohol use, first-degree family history of any cancer (FHC), and diabetes in the Han Chinese ethnic group. In this clinic-based case-control analysis on 385 patients with sporadic PNETs and 614 age- and sex-matched controls, we interviewed subjects using a specific questionnaire on demographics and potential risk factors. An unconditional multivariable logistic regression analysis was used to estimate adjusted odds ratios (AORs)...
October 26, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27770283/accounting-for-individualized-competing-mortality-risks-in-estimating-postmenopausal-breast-cancer-risk
#10
Mara A Schonberg, Vicky W Li, A Heather Eliassen, Roger B Davis, Andrea Z LaCroix, Ellen P McCarthy, Bernard A Rosner, Rowan T Chlebowski, Susan E Hankinson, Edward R Marcantonio, Long H Ngo
PURPOSE: Accurate risk assessment is necessary for decision-making around breast cancer prevention. We aimed to develop a breast cancer prediction model for postmenopausal women that would take into account their individualized competing risk of non-breast cancer death. METHODS: We included 73,066 women who completed the 2004 Nurses' Health Study (NHS) questionnaire (all ≥57 years) and followed participants until May 2014. We considered 17 breast cancer risk factors (health behaviors, demographics, family history, reproductive factors) and 7 risk factors for non-breast cancer death (comorbidities, functional dependency) and mammography use...
December 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27689254/doctors-recognition-and-management-of-melanoma-patients-risk-an-australian-population-based-study
#11
C M Madronio, B K Armstrong, C G Watts, C Goumas, R L Morton, A Curtin, S W Menzies, G J Mann, J F Thompson, A E Cust
BACKGROUND: Guidelines recommend that health professionals identify and manage individuals at high risk of developing melanoma, but there is limited population-based evidence demonstrating real-world practices. OBJECTIVE: A population-based, observational study was conducted in the state of New South Wales, Australia to determine doctors' knowledge of melanoma patients' risk and to identify factors associated with better identification and clinical management. METHODS: Data were analysed for 1889 patients with invasive, localised melanoma in the Melanoma Patterns of Care study...
December 2016: Cancer Epidemiology
https://www.readbyqxmd.com/read/27684037/streamlined-genetic-education-is-effective-in-preparing-women-newly-diagnosed-with-breast-cancer-for-decision-making-about-treatment-focused-genetic-testing-a-randomized-controlled-noninferiority-trial
#12
Veronica F Quinn, Bettina Meiser, Judy Kirk, Kathy M Tucker, Kaaren J Watts, Belinda Rahman, Michelle Peate, Christobel Saunders, Elizabeth Geelhoed, Margaret Gleeson, Kristine Barlow-Stewart, Michael Field, Marion Harris, Yoland C Antill, Linda Cicciarelli, Karen Crowe, Michael T Bowen, Gillian Mitchell
PURPOSE: Increasingly, women newly diagnosed with breast cancer are being offered treatment-focused genetic testing (TFGT). As the demand for TFGT increases, streamlined methods of genetic education are needed. METHODS: In this noninferiority trial, women aged <50 years with either a strong family history (FH+) or other features suggestive of a germ-line mutation (FH-) were randomized before definitive breast cancer surgery to receive TFGT education either as brief written materials (intervention group (IG)) or during a genetic counseling session at a familial cancer clinic (usual-care group (UCG))...
September 29, 2016: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/27679672/environmental-and-lifestyle-risk-factors-of-breast-cancer-in-malta-a-retrospective-case-control-study
#13
John Paul Cauchi, Liberato Camilleri, Christian Scerri
AIM AND BACKGROUND: Environmental exposures are known to play a role in the development of cancer, including breast cancer. There are known associations of breast cancer with environmental factors such as sunlight exposure, diet and exercise and alcohol consumption as well as physiological factors. This study examines the prevalence of risk factors for breast cancer related to dietary intake, environment and lifestyle in the female population of Malta. Malta has had little research in this area, and therefore an exploratory study was carried out...
2016: EPMA Journal
https://www.readbyqxmd.com/read/27645528/urologists-current-practices-in-screening-and-treating-men-with-a-family-history-of-prostate-cancer
#14
Lauren Rudichuk, Kristen J Vogel, Chi-Hsiung Wang, Brian T Helfand, Christina G Selkirk
OBJECTIVE: To assess urologists' knowledge and utilization of family history in order to determine prostate cancer (PC) screening and treatment recommendations. METHODS: Questionnaires that explored urologists' knowledge, frequency and utilization of family history information for screening and treatment recommendations for PC was prospectively collected. Data were summarized and compared using descriptive statistics. RESULTS: A total of 87 responses were collected, for a response rate of 60% (87/145)...
September 16, 2016: Urology
https://www.readbyqxmd.com/read/27644615/assessment-of-breast-cancer-knowledge-among-health-workers-in-bangui-central-african-republic-a-cross-sectional-study
#15
Augustin Balekouzou, Ping Yin, Christian Maucler Pamatika, Sylvain Wilfrid Nambei, Marceline Djeintote, Eric Doromandji, Andre Richard Gouaye, Pascal Gastien Yamba, Elysee Ephraim Guessy, Bertrand Ba-Mpoutou, Dieubeni Rawago Mandjiza, Chang Shu, Minghui Yin, Zhen Fu, Tingting Qing, Mingming Yan, Grace Mella, Boniface Koffi
BACKGROUND: Breast cancer is the leading cause of cancer deaths among women worldwide. High breast cancer mortality has been attributed to lack of public awareness of the disease. Little is known about the level of knowledge of breast cancer in Central African Republic. This study aimed to investigate the knowledge of health professionals on breast cancer. MATERIALS AND METHODS: This cross-sectional study was conducted among 158 health professionals (27 medical; 131 paramedical) in 17 hospitals in Bangui using a self-administered questionnaire...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27639031/psychological-factors-associated-with-the-intention-to-choose-for-risk-reducing-mastectomy-in-family-cancer-clinic-attendees
#16
C M G van Driel, J C Oosterwijk, E J Meijers-Heijboer, C J van Asperen, I A Zeijlmans van Emmichoven, J de Vries, M J E Mourits, L Henneman, D R M Timmermans, G H de Bock
OBJECTIVES: Women seeking counseling because of familial breast cancer occurrence face difficult decisions, such as whether and when to opt for risk-reducing mastectomy (RRM) in case of BRCA1/2 mutation. Only limited research has been done to identify the psychological factors associated with the decision for RRM. This study investigated which psychological factors are related to the intention to choose for RRM. MATERIALS & METHODS: A cohort of 486 cancer-unaffected women with a family history of breast cancer completed the following questionnaires prior to genetic counseling: the Cancer Worry Scale, Positive And Negative Affect Scale, Perceived Personal Control Scale, Hospital Anxiety and Depression Scale and State Anxiety Scale and questions regarding socio-demographic characteristics, family history, risk perception and RRM intention...
December 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/27635286/the-level-of-knowledge-and-awareness-about-prostate-cancer-in-the-turkish-male-and-the-relevant-effective-factors
#17
Sadi Turkan, Faruk Doğan, Ozan Ekmekçioğlu, Aslıhan Çolak, Mehmet Kalkan, Çoşkun Şahin
OBJECTIVE: Our aim was to determine the general knowledge and awareness levels, information sources, and the state of medical check-up for prostate cancer (PCa) and relevant effective factors. MATERIAL AND METHODS: The participants were asked to answer to 14 questions of a questionnaire about age, education, economic and social condition, knowledge about PCa, state of being examined and their related factors. According to demographic characteristics of the participants, levels of awareness about PCa, sources of information, affecting factors and their interrelationships were examined...
September 2016: Turkish Journal of Urology
https://www.readbyqxmd.com/read/27629874/factors-associated-with-cancer-worries-in-individuals-participating-in-annual-pancreatic-cancer-surveillance
#18
Ingrid C A W Konings, Femme Harinck, Marianne A Kuenen, Grace N Sidharta, Jacobien M Kieffer, Cora M Aalfs, Jan-Werner Poley, Ellen M A Smets, Anja Wagner, Anja van Rens, Frank P Vleggaar, Margreet G E M Ausems, Paul Fockens, Jeanin E van Hooft, Marco J Bruno, Eveline M A Bleiker
It is important to adequately and timely identify individuals with cancer worries amongst participants in a pancreatic ductal adenocarcinoma (PDAC) surveillance program, because they could benefit from psychosocial support to decrease distress. Therefore, the aim of this study was to assess both psychosocial and clinical factors associated with cancer worries. High-risk individuals participating in PDAC-surveillance were invited to annually complete a cancer worry scale (CWS) questionnaire which was sent after counseling by the clinical geneticist (T0), after intake for participation in PDAC-surveillance (T1), and then annually after every MRI and endoscopic ultrasonography (EUS) (T2 and further)...
September 14, 2016: Familial Cancer
https://www.readbyqxmd.com/read/27581128/a-collaborative-approach-to-cancer-risk-assessment-services-using-genetic-counselor-extenders-in-a-multi-system-community-hospital
#19
Stephanie A Cohen, Dawn M Nixon
PURPOSE: This study aimed to evaluate a unique approach to cancer risk assessment for improved access by smaller rural communities. METHODS: Local, on-site nurse navigators were trained and utilized as genetic counselor extenders (GCEs) to provide basic risk assessment and offer BRCA1/2 genetic testing to select patients based on a triaging process in collaboration with board-certified genetic counselors (CGCs). RESULTS: From August 2012 to July 2014, 12,477 family history questionnaires representing 8937 unique patients presenting for a screening mammogram or new oncology appointment were triaged...
October 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27577200/-knowledge-and-willingness-of-breast-cancer-patients-from-shanghai-for-genetic-counseling-and-gene-testing
#20
Xiaolin Cheng, Zhengdong Li, Xiaoyin Sun, Beiqi Jiang, Zhigang Zhuang
OBJECTIVE: To investigate the knowledge and willingness of breast cancers patients from Shanghai for genetic counseling and gene testing. METHODS: A total of 428 patients filled out the questionnaire and the data was statistically analyzed. RESULTS: Most of the patients were unaware of genetic counseling and gene testing. But after a brief introduction, a majority of them were willing to accept genetic counseling and recommend their family members to participate...
October 2016: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
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