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https://www.readbyqxmd.com/read/28638010/-evaluating-an-effectiveness-of-surgical-treatment-of-gastroesophageal-reflux-disease-combined-with-hiatal-hernia
#1
V V Mozharovskiy, A A Tsyganov, K V Mozharovskiy, A A Tarasov
AIM: To assess an effectiveness of surgical treatment of gastroesophageal reflux disease (GERD) combined with hiatal hernia (HH). MATERIAL AND METHODS: The trial included 96 patients with GERD and HH who were divided into 2 groups. The principal difference between groups was the use of surgery in the main group and therapeutic treatment in the comparison group. RESULTS: The effectiveness of surgical treatment is superior to therapeutic treatment of GERD by more than 2...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28635199/a-case-of-obstructive-sleep-apnea-syndrome-associated-with-floppy-eyelid-syndrome-positive-effect-of-cpap-therapy
#2
Roberto Porta, Laura Comini, Luca Barbano, Luca Bianchi, Michele Vitacca
The obstructive sleep apnoea syndrome (OSAS) may be associated with several eyes disorders, among which the most common is the floppy eyelid syndrome (FES). We intended to highlight the association between OSAS and FES and evaluate the effect of FES treatment with Continuous Positive Airway Pressure (CPAP). A 50-year patient with a 10-year history of snoring, sleep fragmentation and daytime sleepiness associated with several comorbidities has been studied. For six months, several ocular symptoms were present, particularly on waking up in the morning...
May 18, 2017: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/28603930/successful-retrieval-of-embolized-atrial-septal-defect-occluder-and-patent-foramen-ovale-closure-device-using-novel-coronary-wire-trap-technique
#3
Alireza Khosravi, Ahmad Mirdamadi, Mohammad Reza Movahed
The use of atrial septal device occluders can lead to device embolization. This major complication can occur due to loose margins, deficient aorta, or thin and floppy posterior rim. Device embolization most often occurs after device release, and retrieval is essential. Many devices, including snare and bioptome, have been utilized for retrieval. However, performing these procedures can be difficult and time consuming. Failure to retrieve the embolized device requires open heart surgery. We report a novel and easy to perform method, "coronary wire trap technique," in the event of retrieval failure using conventionally available devices and snare, thereby preventing open-heart surgery...
June 11, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28550871/gastroesophageal-reflux
#4
Bethany J Slater, Steven S Rothenberg
Gastroesophageal reflux disease (GERD) is a very common condition and affects approximately 7-20% of the pediatric population. Symptoms from pathological GERD include regurgitation, irritability when feeding, respiratory problems, and substernal pain. Treatment typically starts with dietary modifications and postural changes. Antireflux medications may then be added. Indications for operative management in the pediatric population include failure of medical therapy with poor weight gain or failure to thrive, continued respiratory symptoms, and complications such as esophagitis...
April 2017: Seminars in Pediatric Surgery
https://www.readbyqxmd.com/read/28530080/-cataract-surgery-complications-in-males-treated-with-alpha-1-antagonists-for-benign-prostatic-hyperplasia
#5
REVIEW
Tamar Pedut Kloizman, Raneen Shehadeh Mashour
Intraoperative floppy iris syndrome (IFIS) was first described by Chang and Campbell in 2005. The characteristics of this syndrome include: 1. Floppy iris that billows in reaction to intraocular fluid currents during standard phacoemulsification procedure; 2. Flaccid iris stroma that tends to prolapse through well-constructed surgical incisions; 3. Insufficient pupillary mydriasis despite proper pharmacologic preparation and progressive pupillary constriction during the operation. Surgical procedures with IFIS have since been noted to have an exceptionally high rate of complications, some of which can be vision threatening...
September 2016: Harefuah
https://www.readbyqxmd.com/read/28505196/unveiling-a-novel-transient-druggable-pocket-in-bace-1-through-molecular-simulations-conformational-analysis-and-binding-mode-of-multisite-inhibitors
#6
Ornella Di Pietro, Jordi Juárez-Jiménez, Diego Muñoz-Torrero, Charles A Laughton, F Javier Luque
The critical role of BACE-1 in the formation of neurotoxic ß-amyloid peptides in the brain makes it an attractive target for an efficacious treatment of Alzheimer's disease. However, the development of clinically useful BACE-1 inhibitors has proven to be extremely challenging. In this study we examine the binding mode of a novel potent inhibitor (compound 1, with IC50 80 nM) designed by synergistic combination of two fragments-huprine and rhein-that individually are endowed with very low activity against BACE-1...
2017: PloS One
https://www.readbyqxmd.com/read/28496999/the-clinical-manifestations-and-genetic-implications-of-baraitser-winter-syndrome-type-2
#7
Tanya C Allawh, Barry Scott Brown
An 18-year-old Caucasian male was born by cesarean section weighing 2.6 kg (5 lb 14 oz) at birth after an uncomplicated pregnancy with no perinatal complications. Around 4 to 5 months of age, the patient's mother initially became concerned as he was experiencing signs of developmental delay and a mild floppy tone, in addition to facial features that resembled some form of mental retardation. The patient's older brother also experienced similar developmental symptoms and facial features that presented around the same age period as our patient...
June 2017: Journal of Pediatric Genetics
https://www.readbyqxmd.com/read/28412810/ultraviolet-light-makes-dgmp-floppy-femtosecond-stimulated-raman-spectroscopy-of-2-deoxyguanosine-5-monophosphate
#8
Joohyun Lee, J Reddy Challa, David W McCamant
The ultrafast dynamics of 2'-deoxyguanosine 5'-monophosphate after excitation with ultraviolet light has been studied with femtosecond transient absorption (TA) and femtosecond stimulated Raman spectroscopy (FSRS). TA kinetics and transient anisotropy spectra reveal a rapid relaxation from the Franck-Condon region, producing an extremely red-shifted stimulated emission band at ∼440 nm that is formed after 200 fs and subsequent relaxation for 0.8-1.5 ps, consistent with prior studies. Viscosity dependence shows that the initial relaxation, before 0...
May 11, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28374870/transoral-robotic-surgery-tors-a-new-tool-for-high-risk-tracheostomy-decannulation
#9
F Montevecchi, G Cammaroto, G Meccariello, P T Hoff, R M Corso, C Galletti, M F H Al-Rawashdeh, C Vicini
Tracheostomy decannulation has always been considered a procedure with an attendant risk, especially in patients with a reduced upper airway diameter as is commonly observed in the obstructive sleep apnoea (OSA) population. We report on 4 cases where transoral robotic surgery (TORS) helped in the management of long-term cannulated patients. The aims of our paper are: 1. To demonstrate how the otolaryngology team can help identify patients at high risk for decannulation failure; and 2. To demonstrate how TORS may aid in the decannulation process of patients at high risk for failure due to severe tongue base hypertrophy...
February 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28330990/on-the-growth-and-form-of-shoots
#10
Raghunath Chelakkot, L Mahadevan
Growing plant stems and shoots exhibit a variety of shapes that embody growth in response to various stimuli. Building on experimental observations, we provide a quantitative biophysical theory for these shapes by accounting for the inherent observed passive and active effects: (i) the active controllable growth response of the shoot in response to its orientation relative to gravity, (ii) proprioception, the shoot's growth response to its own observable current shape, and (iii) the passive elastic deflection of the shoot due to its own weight, which determines the current shape of the shoot...
March 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28323432/electronic-structures-and-oh-induced-atmospheric-degradation-of-cf3nsf2-a-potential-green-dielectric-replacement-for-sf6
#11
Lin Cheng, Xiaojuan Yu, Kun Zhao, Hua Hou, Baoshan Wang
Electronic structures of [(trifluoromethyl)imino]sulfur difluoride (CF3NSF2) and degradation mechanisms by hydroxyl radical have been investigated using density functional theory (M06-2X), the complete basis set quadratic CBS-Q, and the explicitly correlated coupled-cluster methods [CCSD(T)-F12]. The d-function augmented correlation-consistent basis sets including triple- and quadruple-ξ were employed for the sulfur-containing species. It was found that CF3NSF2 exists as two conformations connected by the internal rotation of CF3 around the central NS bond...
March 28, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28317682/intraocular-lens-scaffold-technique-to-prevent-posterior-capsule-rupture-in%C3%A2-cases%C3%A2-of-morgagnian-cataract
#12
Rohit Om Parkash, Shruti Mahajan, Tushya Om Parkash, Vittal Nayak
We describe a technique for performing safe phacoemulsification of a Morgagnian cataract using the intraocular lens (IOL) scaffold. An IOL scaffold has been used in cases in which posterior capsule rupture has occurred, leaving nonemulsified nuclear pieces. The scaffold provides a barrier that prevents the nuclear fragments from falling posteriorly into the vitreous cavity. Our technique uses the IOL as a scaffold to prevent the vulnerable posterior capsule from rupturing during nuclear emulsification in Morgagnian cataract...
January 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28270403/floppy-eyelid-syndrome-delayed-diagnosis-is-not-desired
#13
Amar Pujari, Mandeep S Bajaj, Srikant Kumar Padhy, Divya Agarwal
No abstract text is available yet for this article.
March 7, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28257133/phytotherapy-and-intraoperative-floppy-iris-syndrome-the-implications
#14
M Tsatsos, C MacGregor, I Athanasiadis, M Moschos, A Mataftsi, N Ziakas
No abstract text is available yet for this article.
June 2017: Eye
https://www.readbyqxmd.com/read/28230164/dynamical-majorana-edge-modes-in-a-broad-class-of-topological-mechanical-systems
#15
Emil Prodan, Kyle Dobiszewski, Alokik Kanwal, John Palmieri, Camelia Prodan
Mechanical systems can display topological characteristics similar to that of topological insulators. Here we report a large class of topological mechanical systems related to the BDI symmetry class. These are self-assembled chains of rigid bodies with an inversion centre and no reflection planes. The particle-hole symmetry characteristic to the BDI symmetry class stems from the distinct behaviour of the translational and rotational degrees of freedom under inversion. This and other generic properties led us to the remarkable conclusion that, by adjusting the gyration radius of the bodies, one can always simultaneously open a gap in the phonon spectrum, lock-in all the characteristic symmetries and generate a non-trivial topological invariant...
February 23, 2017: Nature Communications
https://www.readbyqxmd.com/read/28208546/re-assessment-of-urologists-knowledge-of-intraoperative-floppy-iris%C3%A2-syndrome
#16
David S Wang
No abstract text is available yet for this article.
March 2017: Journal of Urology
https://www.readbyqxmd.com/read/28176044/lens-management-of-cataract-surgery-cataract-prevention-and-floppy-iris-syndrome
#17
Joao Crispim, Wallace Chamon
According to the World Health Organization, cataract is the major cause of reversible visual impairment in the world. It is present as the cause of decreased visual acuity in 33% of the visual impaired citizens. With the increase of life expectancy in the last decades, the number of patients with cataract is expected to grow for the next 20 years. Nowadays, the only effective treatment for cataracts is surgery and its surgical outcomes have been increasingly satisfactory with the technological advancement...
2017: Handbook of Experimental Pharmacology
https://www.readbyqxmd.com/read/28162794/corrigendum-to-combined-medial-canthopexy-and-lateral-tarsal-strip-for-floppy-eyelid-syndrome-am-j-otolaryngol-37-2016-240-244
#18
Christopher J Compton, Andrew T Melson, Jeremy D Clark, Taha Z Shipchandler, William R Nunery, H B Harold Lee
No abstract text is available yet for this article.
February 2, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28138983/a-floppy-hat-shaped-reconstruction-for-giant-coronary-ostial-aneurysms-after-a-bentall-operation
#19
Seok In Lee, Chang Hyu Choi, Kook Yang Park, Chul-Hyun Park
No abstract text is available yet for this article.
February 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28112155/transformable-topological-mechanical-metamaterials
#20
D Zeb Rocklin, Shangnan Zhou, Kai Sun, Xiaoming Mao
Mechanical metamaterials are engineered materials whose structures give them novel mechanical properties, including negative Poisson's ratios, negative compressibilities and phononic bandgaps. Of particular interest are systems near the point of mechanical instability, which recently have been shown to distribute force and motion in robust ways determined by a nontrivial topological state. Here we discuss the classification of and propose a design principle for mechanical metamaterials that can be easily and reversibly transformed between states with dramatically different mechanical and acoustic properties via a soft strain...
January 23, 2017: Nature Communications
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