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Subramaniyan Ramanathan, Michele Bertolotto, Ahmad Shamsodini, Mahmoud Heidous, Vikram Dogra, Parvati Ramchandani
OBJECTIVE: The objective of our article is to review the role of imaging in the diagnosis of various complications of a penile prosthesis (PP). CONCLUSION: Complications of a PP can be categorized into three groups: first, malpositioning, which includes buckling, floppy glans, erosion, migration, and crossover; second, mechanical failure, which includes fracture, aneurysm, and leakage; and, third, infection. Radiography, sonography, CT, and MRI are useful in the detection of these complications and complement each other, with MRI being the most useful imaging modality among them...
March 12, 2018: AJR. American Journal of Roentgenology
Salvatore Cillino, Aissa Iggui, Simona Di Naro, Giovanni Cillino, Domenica Matranga, Walter Mazzucco, Fanny Pojero, Alessandra Casuccio
PURPOSE: To analyze the frequency of inappropriate hospitalization in cataract surgery and the type of related determinants. METHODS: A nested retrospective case-control study was carried out on 2708 consecutive cataract surgery patients operated between January 2013 and December 2015. All cases with inappropriate hospitalization (day surgery or ordinary hospitalization) were compared with a control group of cases treated in an appropriate (day service) regimen...
March 8, 2018: International Ophthalmology
Di Zhou, Leyou Zhang, Xiaoming Mao
Disordered fiber networks are ubiquitous in a broad range of natural (e.g., cytoskeleton) and manmade (e.g., aerogels) materials. In this Letter, we discuss the emergence of topological floppy edge modes in two-dimensional fiber networks as a result of deformation or active driving. It is known that a network of straight fibers exhibits bulk floppy modes which only bend the fibers without stretching them. We find that, interestingly, with a perturbation in geometry, these bulk modes evolve into edge modes. We introduce a topological index for these edge modes and discuss their implications in biology...
February 9, 2018: Physical Review Letters
Shohei Okazaki, Takanori Abe, Natsuko Takayanagi, Masanori Yasuda, Fumikazu Sakai, Kunihiko Kobayashi, Shingo Kato
BACKGROUND/AIM: We report on a case of pulmonary tumor embolism caused by squamous cell carcinoma of the uterine cervix. PATIENTS AND METHODS: A 60-year-old female diagnosed with stage IVB (cT4N1M1) squamous cell carcinoma of the uterine cervix was admitted to our institution with a chief complaint of progressive dyspnea that developed within a few days after admission. RESULTS: A chest CT scan showed dilated pulmonary arteries, right ventricular enlargement and mosaic ground-glass opacities in both lungs...
March 2018: In Vivo
Ying-Ying Gao, Hong-Juan Wang, You Wu
BACKGROUND: Known causes of superficial punctuate keratopathy (SPK) in children include entropion, viral infection, blepharokeratoconjunctivitis (BKC), and toxicity of eye drops. However, there are some SPK patients whose causes could not be identified well. Herein, we describe the history, diagnosis, treatment, and prognosis of a rare case. CASE PRESENTATION: To report a case of superficial punctate keratopathy (SPK) which coexisted with floppy eyelid syndrome (FES) and presented as intermittent red eye and blurred vision in an 11-year-old boy who slept in the prone position...
February 23, 2018: BMC Ophthalmology
Petrus S S Castelijns, Marcel C G van de Poll, Johannes F Smulders
INTRODUCTION: Nissen fundoplication is frequently applied in the surgical treatment of patients with gastroesophageal reflux disease (GERD). When the gastroesophageal junction remains too large or becomes too narrow, persistent GERD or dysphagia may occur. To assure a correct size of the gastroesophageal junction, the fundoplication can be created over a bougie. However, this increases the risk of esophageal perforation. Therefore, we have modified a previously described technique to create a standardized fundoplication without the use of a bougie...
February 21, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
Ahmed Adam
Objective: To describe a simple, novel method to achieve ureteric access in the Cohen crossed reimplanted ureter, which will allow retrograde working access via the conventional transurethral method. Materials and Methods: Under cystoscopic vision, suprapubic needle puncture was performed. The needle was directed (bevel facing) towards the desired ureteric orifice (UO). A guidewire (with a floppy-tip) was then inserted into the suprapubic needle passing into the bladder, and then easily passed into the crossed-reimplanted UO...
November 2017: Current Urology
Kaveh Vahdani, Rebecca Ford, Helen Garrott, Vladimir Theodor Thaller
OBJECTIVES: To compare the functional and anatomical outcomes of lateral tarsal strip (LTS) with Bick's procedure in treatment of eyelid malposition. METHODS: A retrospective, consecutive case series of patients who underwent LTS and Bick's procedure for all types of involutional lower eyelid malposition, at two centers between January 2012 and 2015. Statistical analyses of differences between groups were performed using the Fisher's exact test to compare non-continuous variables and Mann-Whitney U test for continuous variables...
February 21, 2018: Eye
Denise Visco
Purpose: To evaluate the effect of intracameral phenylephrine/ketorolac (1%/0.3%) during cataract surgery on the use of iris fixation ring and surgical time in patients with poor pupil dilation (≤5.0 mm) or intraoperative floppy iris syndrome (IFIS). Setting: Private practice outpatient surgical center. Design: This retrospective analysis was conducted from January 1, 2014 to October 7, 2015. Materials and methods: The use of iris fixation rings was evaluated in a retrospective analysis of 46 patients who underwent cataract surgery from January 1, 2014, to October 7, 2015, and who were identified before surgery to be at risk for intraoperative miosis...
2018: Clinical Ophthalmology
Hao Hu, Pablo Sampedro Ruiz, Ran Ni
Grafting linkers with open ends of complementary single-stranded DNA makes a flexible tool to tune interactions between colloids, which facilitates the design of complex self-assembly structures. Recently, it has been proposed to coat colloids with mobile DNA linkers, which alleviates kinetic barriers without high-density grafting, and also allows the design of valency without patches. However, the self-assembly mechanism of this novel system is poorly understood. Using a combination of theory and simulation, we obtain phase diagrams for the system in both two and three dimensional spaces, and find stable floppy square and CsCl crystals when the binding strength is strong, even in the infinite binding strength limit...
January 26, 2018: Physical Review Letters
Sophie D West, Chris Turnbull
Obstructive sleep apnoea (OSA) is increasing in prevalence due to rising obesity. While OSA is a disorder primarily of the upper airway during sleep, its pathophysiological impact on other body systems is increasingly recognised. There has been interest in the prevalence of OSA in different ophthalmic conditions and possible causation has been postulated. As OSA is common, it can be expected that people with co-existent OSA will be found in any ophthalmic disease population studied. To determine with confidence the significance of finding patients with OSA in a particular cohort requires a well matched control group, ideally matched for age, obesity, gender and co-morbidities...
February 2, 2018: Eye
Chia-Chen Lee, Hsin-Ti Lai, Yur-Ren Kuo, Su-Shin Lee, Chung-Sheng Lai
BACKGROUND: Floppy eyelid syndrome (FES) is typically characterized by chronic eye irritation and an increased laxity of the upper eyelid that can be easily everted by applying minimal upward traction. However, it is a clinical entity that is less known to most plastic surgeons. Blepharoptosis is one of the most common features, which links to FES, for which a thorough differential diagnosis has become important in directing proper medical treatment. PURPOSE: This review aims to discuss current understanding about FES in a broader spectrum, encompassing the clinical features and evaluation of FES, the underlying etiologies, systemic associations, and surgical procedures for upper eyelid tightening...
February 2018: Annals of Plastic Surgery
Mathijs F J Vermeulen, Anwesha Bose, Cornelis Storm, Wouter G Ellenbroek
Disordered spring networks that are undercoordinated may abruptly rigidify when sufficient strain is applied. Since the deformation in response to applied strain does not change the generic quantifiers of network architecture, the number of nodes and the number of bonds between them, this rigidity transition must have a geometric origin. Naive, degree-of-freedom-based mechanical analyses such as the Maxwell-Calladine count or the pebble game algorithm overlook such geometric rigidity transitions and offer no means of predicting or characterizing them...
November 2017: Physical Review. E
Marco Bernini, Donato Casella, Carlo Mariotti
The use of pectoralis major muscle (PMM) in breast reconstruction has been a mainstay for decades. In recent years, although, a novel approach, the so-called subcutaneous or pre-pectoral breast reconstruction, has been introduced advocating the advantages of sparing the pectoralis muscle. Such advantages include more natural implant ptosis and appearance, significant reduction of capsular contracture and also avoidance of implant animation and animation deformities. These are all drawbacks that the use of muscles in implant coverage inevitably involves overtime...
December 2017: Gland Surgery
Camilo Toro, Roderick T Hori, May Christine V Malicdan, Cynthia J Tifft, Amy Goldstein, William A Gahl, David R Adams, Fauni Harper, Lynne A Wolfe, Jianfeng Xiao, Mohammad M Khan, Jun Tian, Kevin A Hope, Lawrence T Reiter, Michel G Tremblay, Thomas Moss, Alexis L Franks, Chris Balak, Mark S LeDoux
UBTF (upstream binding transcription factor) exists as two isoforms; UBTF1 regulates rRNA transcription by RNA polymerase 1, whereas UBTF2 regulates mRNA transcription by RNA polymerase 2. Herein, we describe 4 patients with very similar patterns of neuroregression due to recurrent de novo mutations in UBTF (GRCh37/hg19, NC_000017.10:g.42290219C>T, NM_014233.3:c.628G>A) resulting in the same amino acid change in both UBTF1 and UBTF2 (p.Glu210Lys [p.E210K]). Disease onset in our cohort was at 2.5 to 3 yrs and characterized by slow progression of global motor, cognitive and behavioral dysfunction...
January 2, 2018: Human Molecular Genetics
Jing-Min Liu, Yu Zhai, Xiao-Long Zhang, Hui Li
A thorough understanding of the intermolecular configurations of van der Waals complexes is a great challenge due to their weak interactions, floppiness and anharmonic nature. Although high-resolution microwave or infrared spectroscopy provides one of the most direct and precise pieces of experimental evidence, the origin and key role in determining such intermolecular configurations of a van der Waals system strongly depend on its highly accurate potential energy surface (PES) and a detailed analysis of its ro-vibrational wavefunctions...
January 4, 2018: Physical Chemistry Chemical Physics: PCCP
Dušan Petrović, David Frank, Shina Caroline Lynn Kamerlin, Kurt Hoffmann, Birgit Strodel
Glucose oxidase has wide applications in the pharmaceutical, chemical, and food industries. Many recent studies have enhanced key properties of this enzyme using directed evolution, yet without being able to reveal why these mutations are actually beneficial. This work presents a synergistic combination of experimental and computational methods, indicating how mutations, even when distant from the active site, positively affect glucose oxidase catalysis. We have determined the crystal structures of glucose oxidase mutants containing molecular oxygen in the active site...
September 1, 2017: ACS Catalysis
Rachel K Putman, Robert L Owens
No abstract text is available yet for this article.
December 2017: Annals of the American Thoracic Society
Alina Pflügner, Ulrich Thome, Matthias K Bernhard, Mandy Vogel, Annett Bläser, Petra Nickel, Wieland Kiess
OBJECTIVE:  Methamphetamine (MA) has become one of the most commonly used illegal drugs during pregnancy. We sought to determine how MA abuse modifies pregnancy outcomes and the health of the newborn infants. Patients 102 newborns from mothers with antenatal MA consumption were admitted to the University Hospital Leipzig from 2004-2015. METHODS:  The effects of MA abuse on pregnancy outcomes and neonates were researched in a retrospective controlled study. We analysed the date of pregnancy detection, number of antenatal preventive examinations, body measurements of the neonates, duration of hospitalization, rate of preterm infants, congenital malformations and symptoms of neonatal abstinence syndrome...
January 2018: Klinische Pädiatrie
Cem Bayraktar, Ali Şimşek
Bayraktar C, Şimşek A. Evaluation of choroidal thickness measurements in pediatric obstructive sleep apnea syndrome patients. Turk J Pediatr 2017; 59: 62-67. Choroidal vascular impairment and obstructive sleep apnea syndrome (OSAS) related disorders have been shown in adults, but there have been no investigations with regard to the choroidal thickness measurements in children with OSAS. Our aim was to investigate this relationship in the early childhood period, which correlates with OSAS peak incidence due to adenotonsillar enlargement...
2017: Turkish Journal of Pediatrics
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