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https://www.readbyqxmd.com/read/27922142/prevalence-and-risk-factors-of-caregiver-dependence-among-older-adults-in-a-southeast-asian-population
#1
Louisa Picco, Edimansyah Abdin, Janhavi A Vaingankar, Shirlene Pang, Saleha Shafie, Rajeswari Sambasivam, Siow Ann Chong, Mythily Subramaniam
INTRODUCTION: Currently very little is known about the prevalence or magnitude of caregiver dependence in Singapore and thus, there is a need to fill this gap in this multiethnic ageing population. This study aims to determine the prevalence and risk factors of caregiver dependence among older adults in Singapore. MATERIALS AND METHODS: Data were used from the Well-being of the Singapore Elderly (WiSE) study, a nationally representative, cross-sectional survey among Singapore residents aged 60 years and above...
November 2016: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/27920169/chikungunya-its-history-in-africa-and-asia-and-its-spread-to-new-regions-in-2013-2014
#2
Herve Zeller, Wim Van Bortel, Bertrand Sudre
Chikungunya virus (CHIKV) is transmitted by Aedes aegypti and Aedes albopictus mosquitoes and causes febrile illness with severe arthralgia in humans. There are 3 circulating CHIKV genotypes, Asia, East/Central/South Africa, and West Africa. CHIKV was first reported in 1953 in Tanzania, and up until the early 2000s, a few outbreaks and sporadic cases of CHIKV were mainly reported in Africa and Asia. However, from 2004 to 2005, a large epidemic spanned from Kenya over to the southwestern Indian Ocean region, India, and Southeast Asia...
December 15, 2016: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27912112/ethnic-variation-of-genetic-idiopathic-generalized-epilepsy-in-malaysia
#3
Kheng Seang Lim, Ching Ching Ng, Chung Kin Chan, Wee Shean Foo, Joyce Siew Yong Low, Chong Tin Tan
PURPOSE: Ethnic variation in epilepsy classification was reported in the Epilepsy Phenome/Genome Project. This study aimed to determine the ethnic variation in the prevalence of genetic (idiopathic) generalized epilepsy (GGE) and GGE with family history in a multi-ethnic Asian population in Malaysia. METHOD: In this cross-sectional study, 392 patients with a clinical diagnosis of GGE were recruited in the neurology outpatient clinic, University of Malaya Medical Centre (UMMC), from January 2011 till April 2016...
November 24, 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/27905329/recombinant-interferon-alpha-2b-for-ocular-surface-squamous-neoplasia-an-efficient-and-cost-effective-treatment-modality-in-asian-indian-patients
#4
Swathi Kaliki, Swati Singh, Sadiya Iram, Dharani Tripuraneni
PURPOSE: The purpose was to study the efficacy of interferon alpha 2b (INF α2b) in the treatment of ocular surface squamous neoplasia (OSSN) and analyze its cost-effectiveness in India. STUDY DESIGN: This was a retrospective study of thirty patients with OSSN treated with topical INF α2b (1 MIU/cc) ± perilesional INF α2b (5 MIU/cc). RESULTS: The tumor involved cornea (n = 9, 30%), conjunctivo-limbal-corneal surface (n = 19, 63%), or bulbar conjunctiva (n = 2, 7%)...
October 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27893593/trends-in-selected-measures-of-racial-and-ethnic-disparities-in-gonorrhea-and-syphilis-in-the-united-states-1981-2013
#5
Harrell W Chesson, Chirag G Patel, Thomas L Gift, Sevgi O Aral
BACKGROUND: The purpose of this study was to examine selected measures of racial and ethnic disparities in the reported incidence of syphilis and gonorrhea from 1981 to 2013 in the United States. METHODS: For each year, from 1981 to 2013, we calculated values for 5 disparity measures (Gini coefficient, 2 versions of the index of disparity, population attributable proportion, and the black-to-white rate ratio) for 5 racial/ethnic categories (non-Hispanic white, non-Hispanic black, Hispanic, American Indian/Alaska Native, and Asian/Pacific Islander)...
November 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27867888/neck-height-ratio-is-an-important-predictor-of-metabolic-syndrome-among-asian-indians
#6
Chitra Selvan, Deep Dutta, Anubhav Thukral, Titli Nargis, Manoj Kumar, Satinath Mukhopadhyay, Subhankar Chowdhury
BACKGROUND AND AIMS: The predictive potential of neck circumference (NC) based indices (a measure of upper body fat distribution) for predicting metabolic syndrome (MetS) and its components among Indians is not known. This study aimed to evaluate the role of NC and neck height ratio (NHtR) as independent predictors of MetS and its components as compared to traditional anthropometric indices. MATERIALS AND METHODS: A total of 451 individuals from 867 screened individuals, 30-80 years age, without any co-morbid state who gave informed written consent underwent clinical, anthropometric, and biochemical assessment...
November 2016: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27866970/genotype-phenotype-study-of-middle-gangetic-plain-in-india-reveals-association-of-rs2470102-with-skin-pigmentation
#7
Anshuman Mishra, Sheikh Nizammuddin, Chandana Basu Mallick, Sakshi Singh, Satya Prakash, Niyamat Ali Siddiqui, Niraj Rai, S Justin Carlus, D V S Sudhakar, Vishnu P Tripathi, Märt Möls, Xana Kim-Howard, Hemlata Dewangan, Abhishek Mishra, Alla G Reddy, Biswajit Roy, Krishna Pandey, Gyaneshwer Chaubey, Pradeep Das, Swapan K Nath, Lalji Singh, Kumarasamy Thangaraj
Our understanding of genetics of skin pigmentation has been largely skewed towards populations of European ancestry imparting much less attention to South Asian populations, who behold huge pigmentation diversity. Here, we investigate the skin pigmentation variation in a cohort of 1167 individuals in Middle Gangetic Plain of Indian subcontinent. Our data confirms the association of rs1426654 with skin pigmentation among South Asians, consistent with previous studies and also reveals association for rs2470102 SNP...
November 17, 2016: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/27862917/assessing-variation-across-eight-established-east-asian-loci-for-type-2-diabetes-in-american-indians-suggestive-evidence-for-new-sex-specific-diabetes-signals-in-glis3-and-zfand3
#8
Yunhua L Muller, Paolo Piaggi, Peng Chen, Gregory Wiessner, Chidinma Okani, Sayuko Kobes, William C Knowler, Clifton Bogardus, Robert L Hanson, Leslie J Baier
BACKGROUND: Eight new loci for type 2 diabetes (T2D) were identified in an East Asian genome-wide association study meta-analysis. We assess tag SNPs across these loci for associations with T2D in American Indians. METHODS: 435 SNPs which tag (r(2)  ≥ 0.85) common variation across the 8 loci were analyzed for association with T2D (n = 7710), early-onset T2D (n = 1060), body mass index (n = 6839), insulin sensitivity (n = 555) and insulin secretion (n = 298)...
November 8, 2016: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/27862104/the-influence-of-helicobacter-pylori-on-the-ethnic-distribution-of-barrett-s-metaplasia
#9
A Sonnenberg, K O Turner, S J Spechler, R M Genta
BACKGROUND: Environmental risk factors associated with ethnicity may contribute to the occurrence of Barrett's metaplasia. AIM: Our aim was to investigate the interaction between ethnicity and Helicobacter pylori infection in the occurrence of Barrett's metaplasia among patients undergoing oesophago-gastro-duodenoscopy. METHODS: The Miraca Life Sciences Database is an electronic repository of histopathological patient records. A case-control study evaluated the influence of age, gender, ethnicity and histological diagnosis of H...
November 9, 2016: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27858935/multiethnic-involvement-in-autosomal-dominant-optic-atrophy-in-singapore
#10
J L Loo, S Singhal, A V Rukmini, S Tow, P Amati-Bonneau, V Procaccio, D Bonneau, J J Gooley, P Reynier, M Ferré, D Milea
PurposeAutosomal-dominant optic atrophy (ADOA), often associated with mutations in the OPA1 gene (chromosome 3q28-q29) is rarely reported in Asia. Our aim was to identify and describe this condition in an Asian population in Singapore.Patients and methodsPreliminary cross-sectional study at the Singapore National Eye Centre, including patients with clinical suspicion of ADOA, who subsequently underwent genetic testing by direct sequencing of the OPA1 gene.ResultsAmong 12 patients (10 families) with clinically suspected ADOA, 7 patients (5 families) from 3 different ethnic origins (Chinese, Indian, and Malay) carried a heterozygous pathogenic variant in the OPA1 gene...
November 18, 2016: Eye
https://www.readbyqxmd.com/read/27855754/sleep-quality-and-nocturnal-sleep-duration-in-pregnancy-and-risk-of-gestational-diabetes-mellitus
#11
Shirong Cai, Sara Tan, Peter D Gluckman, Keith M Godfrey, Seang-Mei Saw, Oon Hoe Teoh, Yap-Seng Chong, Michael J Meaney, Michael S Kramer, Joshua J Gooley
OBJECTIVE: To examine the influence of maternal sleep quality and nocturnal sleep duration on risk of gestational diabetes mellitus (GDM) in a multi-ethnic Asian population. METHODS: 686 women (376 Chinese, 186 Malay and 124 Indian) with a singleton pregnancy attended a clinic visit at 26-28 weeks of gestation as part of the Growing Up in Singapore Towards healthy Outcomes (GUSTO) mother-offspring cohort study. Self-reported sleep quality and sleep duration were assessed using the Pittsburgh Sleep Quality Index (PSQI)...
November 14, 2016: Sleep
https://www.readbyqxmd.com/read/27855557/201-consecutive-cytoreductive-surgery-crs-and-hyperthermic-intraperitoneal-chemotherapy-hipec-procedures-in-a-single-asian-tertiary-centre
#12
Grace Tan, Claramae Chia, Mrinal Kumar, Su Pin Choo, John Chia, Chee Kian Tham, Khee Chee Soo, Melissa Teo
INTRODUCTION: Peritoneal carcinomatosis (PC) is increasingly being treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). We provide a review of a high-volume Asian institute's experience and survival outcomes with this procedure. METHODS: Data was prospectively collected from 201 consecutive CRS and HIPEC procedures performed in a single institution between April 2001 and November 2015. Our primary endpoints were OS and DFS, and secondary endpoints were morbidity and mortality...
November 17, 2016: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/27855143/trends-in-obesity-among-participants-aged-2-4-years-in-the-special-supplemental-nutrition-program-for-women-infants-and-children-united-states-2000-2014
#13
Liping Pan, David S Freedman, Andrea J Sharma, Karen Castellanos-Brown, Sohyun Park, Ray B Smith, Heidi M Blanck
Childhood obesity is associated with negative health consequences in childhood (1) that continue into adulthood (2), putting adults at risk for type 2 diabetes, cardiovascular disease, and certain cancers (1). Obesity disproportionately affects children from low-income families (3). Through a collaboration with the United States Department of Agriculture (USDA), CDC has begun to use data from the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) Participants and Program Characteristics (WIC PC) to replace the Pediatric Nutrition Surveillance System (PedNSS) (4,5) for obesity surveillance among young children from low-income families...
November 18, 2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27854139/foveal-layer-morphology-detected-on-spectral-domain-optical-coherence-tomography-and-its-correlation-with-visual-acuity-in-asian-indian-premature-infants-in-their-first-year-of-life
#14
Chaitra Jayadev, Anand Vinekar, Shwetha Mangalesh, Mathew Kurian Kummelil, Anupama Kiran Kumar, Vasudha Kemmanu, Munusamy Sivakumar, Padmamalini Mahendradas, Kavitha Avadhani, Noel Bauer, Carroll Ab Webers, Bhujang Shetty
PURPOSE: To report foveal microanatomy imaged on handheld spectral domain optical coherence tomography (SDOCT) and correlate it with visual acuity in Asian Indian premature infants. METHODS: A retrospective analysis of 32 Asian Indian premature infants, 10 with Type 2 retinopathy of prematurity (ROP), were imaged between 3 and 12 months of corrected postmenstrual age (PMA) on the handheld SDOCT (Envisu 2300, Bioptigen, DNC, USA). The foveal findings on these images were correlated with visual acuity measured using Teller acuity cards...
November 17, 2016: Current Eye Research
https://www.readbyqxmd.com/read/27853549/two-species-of-southeast-asian-cats-in-the-genus-catopuma-with-diverging-histories-an-island-endemic-forest-specialist-and-a-widespread-habitat-generalist
#15
Riddhi P Patel, Daniel W Förster, Andrew C Kitchener, Mark D Rayan, Shariff W Mohamed, Laura Werner, Dorina Lenz, Hans Pfestorf, Stephanie Kramer-Schadt, Viktoriia Radchuk, Jörns Fickel, Andreas Wilting
Background. The bay cat Catopuma badia is endemic to Borneo, whereas its sister species the Asian golden cat Catopuma temminckii is distributed from the Himalayas and southern China through Indochina, Peninsular Malaysia and Sumatra. Based on morphological data, up to five subspecies of the Asian golden cat have been recognized, but a taxonomic assessment, including molecular data and morphological characters, is still lacking. Results. We combined molecular data (whole mitochondrial genomes), morphological data (pelage) and species distribution projections (up to the Late Pleistocene) to infer how environmental changes may have influenced the distribution of these sister species over the past 120 000 years...
October 2016: Royal Society Open Science
https://www.readbyqxmd.com/read/27852633/predictors-of-malignancy-in-patients-with-pheochromocytomas-paragangliomas-asian-indian-experience
#16
Kranti Khadilkar, Vijaya Sarathi, Rajeev Kasaliwal, Reshma Pandit, Manjunath Goroshi, Gaurav Malhotra, Abhay Dalvi, Ganesh Bakshi, Anil Bhansali, Rajesh Rajput, Vyankatesh Shivane, Anurag Lila, Tushar Bandgar, Nalini S Shah
BACKGROUND AND AIMS: Malignant transformation of pheochromocytomas/paragangliomas (PCC/PGL) is a rare occurrence, and predictive factors for the same are not well understood. This study aims to identify the predictors of malignancy in patients with PCC/PGL. MATERIALS AND METHODS: We performed a retrospective analysis of 142 patients with either PCC or PGL registered at our institute between 2000 and 2015. Records were evaluated for clinical parameters like age, gender, familial/syndromic presentation, symptomatic presentation, biochemistry, size, number and location of tumours and presence of metastases and mode of its diagnosis...
November 2016: Endocrine Connections
https://www.readbyqxmd.com/read/27849430/the-normalization-of-cannabis-use-among-bangladeshi-and-pakistani-youth-a-new-frontier-for-the-normalization-thesis
#17
Lisa Williams, Rob Ralphs, Paul Gray
BACKGROUND: The Asian population in Britain has grown, representing the second largest ethnic group; Bangladeshi, Pakistani, and Indian nationalities are prevalent (Jivraj, 2012 ; Office for National Statistics, 2013 ). Yet, we know relatively little about the nature and extent of their substance use. Jayakody et al. ( 2006 ) argue ethnic minority groups may be influenced by the norms and values of the dominant culture. Given recreational drug use has undergone a process of normalization in Britain (Aldridge et al...
November 16, 2016: Substance Use & Misuse
https://www.readbyqxmd.com/read/27848187/racial-and-ethnic-disparities-in-diabetes-screening-between-asian-americans-and-other-adults-brfss-2012-2014
#18
Elizabeth L Tung, Arshiya A Baig, Elbert S Huang, Neda Laiteerapong, Kao-Ping Chua
BACKGROUND: Although Asian Americans are at high risk for type 2 diabetes, it is not known whether they are appropriately screened for this disease. OBJECTIVE: To assess racial and ethnic disparities in diabetes screening between Asian Americans and other adults. DESIGN: Analysis of pooled cross-sectional data from 45 U.S. states and territories using the 2012-2014 Behavioral Risk Factor Surveillance System. We calculated the weighted proportions of adults in each racial and ethnic group who received recommended diabetes screening...
November 15, 2016: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/27832219/anxiety-and-depression-in-patients-with-atopic-dermatitis-in-a-southeast-asian-tertiary-dermatological-centre
#19
Vanessa Zy Lim, Roger Cm Ho, Shang Ian Tee, Madeline Sl Ho, Jiun Yit Pan, Yen Loo Lim, Mark By Tang, Keen Loong Chan, Yoke Chin Giam
INTRODUCTION: This study aimed to assess the frequency of anxiety and depression in a cohort of adult patients with atopic dermatitis (AD) in a tertiary dermatological centre, using the Hospital Anxiety and Depression Scale (HADS). We looked for any correlation between anxiety and depression with skin disease severity. MATERIALS AND METHODS: Patients with AD were recruited from the National Skin Centre, Singapore, from 2008 to 2009 for a prospective cross-sectional study...
October 2016: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/27828729/cross-sectional-study-for-the-detection-of-mutations-in-the-beta-globin-gene-among-patients-with-hemoglobinopathies-in-the-bengali-population
#20
Amrita Panja, Prosanto Chowdhury, Sharmistha Chakraborty, Tapan Kumar Ghosh, Anupam Basu
AIMS: Thalassemia is a common autosomal recessive blood disorder, which is most prevalent in South East Asian and Mediterranean populations. It is considered as a major health burden in the Indian population. The aims of the present study were to investigate the common, as well as uncommon, mutations responsible for thalassemia in the Bengali population. METHODS: The Bengali state was divided into four sampling zones. Mutation detection was done using Sanger sequencing of the HBB gene...
November 9, 2016: Genetic Testing and Molecular Biomarkers
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