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https://www.readbyqxmd.com/read/28922908/vitamin-d-status-in-internationally-adopted-children-the-experience-in-northwest-italy
#1
Irene Raffaldi, Silvia Garazzino, Giuseppina Ballardini, Mauro Zaffaroni, Nicolino Grasso, Gianni Bona, Pier-Angelo Tovo, Andrea Guala
BACKGROUND: The majority of internationally adopted children, before adoption, might have experienced malnutrition, exposure to infectious diseases, environmental deprivation and neglect; they could also develop medical problems such as vitamin D deficiency. Scantly data are available about vitamin D status in internationally adopted children and, to our knowledge, no report exists on Italian adoptees. METHODS: We carried out a prospective multicenter study, involving three Pediatric Centers in Piedmont, Italy, in order to collect information about 25-hydroxyvitamin D [25(OH)D] profile in adoptees, shortly after their arrival in Italy...
September 15, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28922874/noninvasive-transfontanelle-monitoring-of-the-intracerebral-pressure-in-comparison-with-an-invasive-intradural-intracranial-pressure-device-a-prospective-study
#2
Bedjan Behmanesh, Marco Bartels, Florian Gessler, Natalie Filmann, Volker Seifert, Matthias Setzer, Thomas M Freiman
BACKGROUND: We previously introduced a novel noninvasive technique of intracranial pressure (ICP) monitoring in children with open fontanelles. OBJECTIVE: To compare the ICP obtained by our new technique to the ICP derived from an intradurally implanted ICP measurement device (external ventricular drain, subdural ICP device). METHODS: Children with open fontanelles and need of intracranial monitoring were included in this study. A standard ICP probe was placed upon the frontal fontanelle and data were compared with the values recorded by an already invasively implanted subdural ICP technique...
October 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28922662/treatment-of-autoimmune-glial-fibrillary-acidic-protein-astrocytopathy-follow-up-in-7-cases
#3
Xinguang Yang, Junyan Liang, Qingmei Huang, Huiming Xu, Cong Gao, Youming Long, Xiaoyu Xiao
OBJECTIVE: The aim of this work was to report an autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy with long-term follow-up in 7 patients. METHODS: Antibodies were detected by indirect immunofluorescence assay and patient data were analyzed retrospectively. RESULTS: Seven patients (4 female, 3 male) with ≥1 year follow-up were included. All patients had positive GFAP antibodies in their cerebral spinal fluid (CSF). Their median age at disease onset was 56 years (range 27-69) and the median disease duration was 1 year (range 1-4)...
September 19, 2017: Neuroimmunomodulation
https://www.readbyqxmd.com/read/28922653/is-willems-method-universal-for-age-estimation-a-systematic-review-and-meta-analysis
#4
REVIEW
Jian Wang, Fang Ji, Yue Zhai, Hyun Park, Jiang Tao
Dental age (DA) has been widely accepted as a way to evaluate chronological age (CA) in recent years. However, the applicability of Willems method, as one of the most popular radiographic ways, still remains controversial in different areas. The aim of this study is to assess the difference between DA and CA with Willems method. Relevant studies published up to February 28th, 2017 were selected via PubMed, Embase, the Cochrane Library, CNKI, CBM and manual search. Studies that examined Willems dental age and chronological age were selected...
September 12, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28922609/serum-proteomic-variability-associated-with-clinical-phenotype-in-familial-transthyretin-amyloidosis-attrm
#5
Gloria G Chan, Clarissa M Koch, Lawreen H Connors
Transthyretin (TTR), normally a plasma circulating protein, can become misfolded and aggregated, ultimately leading to extracellular deposition of amyloid fibrils usually targeted to heart or nerve tissues. Referred to as TTR-associated amyloidoses (ATTR), this group of diseases is frequently life threatening and fatal if untreated. ATTR, caused by amyloid-forming variant TTR proteins (ATTRm) which arise from point mutations in the TTR gene, were classically referred to as familial amyloid cardiomyopathy (FAC) or familial amyloid polyneuropathy (FAP) reflecting the clinical phenotype...
September 18, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28922477/reference-intervals-for-serum-bilirubin-urea-and-uric-acid-in-healthy-chinese-geriatric-population
#6
Yuanqing Yang, Hongmin Jiang, Aiguo Tang, Zhongyuan Xiang
OBJECTIVES: The study aims to establish the reference intervals (RIs) for total bilirubin (TBIL), direct bilirubin (DBIL), urea (UR), and uric acid (UA) in healthy Chinese geriatric population. METHODS: Eight hundred and twenty cases from six representative geographical regions in China (including male 413 cases and female 407 cases) of apparently healthy individuals aged 60-96 years were recruited. Serum TBIL, DBIL, UR, and UA were analyzed by automatic biochemical analyzer and RIs were determined following CLSI C28-A3 guidelines using a non-parametric method...
September 18, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28922454/surgery-for-t4-lung-cancer-invading-the-thoracic-aorta-do-we-push-the-limits
#7
Giuseppe Marulli, Erino A Rendina, Walter Klepetko, Reinhold Perkmann, Davide Zampieri, Giulio Maurizi, Thomas Klikovits, Francesco Zaraca, Federico Venuta, Egle Perissinotto, Federico Rea
BACKGROUND: Few investigators have described en bloc resection of non-small cell lung cancer (NSCLC) invading the aorta. AIM OF STUDY: Analysis of outcome and prognostic factors for en bloc resections of NSCLC invading the aorta. METHODS: Thirty-five patients (27 males, 8 females; mean age 63 ± 8.6 years) were operated between 1994 and 2015 in four European Centers. HISTOLOGY: 12 (34.3%) squamous cell carcinoma, and 6 (17...
September 18, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28922421/effects-of-acute-administration-of-donepezil-or-memantine-on-sleep-deprivation-induced-spatial-memory-deficit-in-young-and-aged-non-human-primate-grey-mouse-lemurs-microcebus-murinus
#8
Anisur Rahman, Yves Lamberty, Esther Schenker, Massimo Cella, Solène Languille, Régis Bordet, Jill Richardson, Fabien Pifferi, Fabienne Aujard
The development of novel therapeutics to prevent cognitive decline of Alzheimer's disease (AD) is facing paramount difficulties since the translational efficacy of rodent models did not resulted in better clinical results. Currently approved treatments, including the acetylcholinesterase inhibitor donepezil (DON) and the N-methyl-D-aspartate antagonist memantine (MEM) provide marginal therapeutic benefits to AD patients. There is an urgent need to develop a predictive animal model that is phylogenetically proximal to humans to achieve better translation...
2017: PloS One
https://www.readbyqxmd.com/read/28922406/loss-of-liver-specific-and-sexually-dimorphic-gene-expression-by-aryl-hydrocarbon-receptor-activation-in-c57bl-6-mice
#9
Rance Nault, Kelly A Fader, Jack R Harkema, Tim Zacharewski
The aryl hydrocarbon receptor (AhR) is a highly conserved transcription factor that mediates a broad spectrum of species-, strain-, sex-, age-, tissue-, and cell-specific responses elicited by structurally diverse ligands including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Dose-dependent effects on liver-specific and sexually dimorphic gene expression were examined in male and female mice gavaged with TCDD every 4 days for 28 or 92 days. RNA-seq data revealed the coordinated repression of 181 genes predominately expressed in the liver including albumin (3...
2017: PloS One
https://www.readbyqxmd.com/read/28922404/eco-epidemiological-analysis-of-rickettsial-seropositivity-in-rural-areas-of-colombia-a-multilevel-approach
#10
Juan C Quintero V, Luis E Paternina T, Alexander Uribe Y, Carlos Muskus, Marylin Hidalgo, Juliana Gil, Astrid Vanessa Cienfuegos G, Lisardo Osorio Q, Carlos Rojas A
Rickettsiosis is a re-emergent infectious disease without epidemiological surveillance in Colombia. This disease is generally undiagnosed and several deadly outbreaks have been reported in the country in the last decade. The aim of this study is to analyze the eco-epidemiological aspects of rickettsial seropositivity in rural areas of Colombia where outbreaks of the disease were previously reported. A cross-sectional study, which included 597 people living in 246 households from nine hamlets in two municipalities of Colombia, was conducted from November 2015 to January 2016...
September 18, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28922367/perihematomal-diffusion-restriction-as-a-common-finding-in-large-intracerebral-hemorrhages-in-the-hyperacute-phase
#11
Tanja Schneider, David Frieling, Julian Schroeder, Jan Regelsberger, Gerhard Schoen, Jens Fiehler, Susanne Gellißen
PURPOSE: There is growing evidence that a perihematomal area of restricted diffusion (PDR) exists in intraparenchymal hemorrhages (IPH) within 1 week of symptom onset (SO). Here, we study characteristics and the clinical impact of the PDR in patients with hyperacute (≤ 6 hours from SO) IPH by means of apparent diffusion coefficient (ADC). METHODS: This monocentric, retrospective study includes 83 patients with first-ever primary IPH from 09/2002-10/2015. 3D volumetric segmentation was performed for the IPH, PDR, and perihematomal edema (PHE) on fluid-attenuated inversion recovery, T2*/susceptibility weighted images, and ADC images...
2017: PloS One
https://www.readbyqxmd.com/read/28922269/extubation-failure-is-associated-with-increased-mortality-following-first-stage-single-ventricle-reconstruction-operation
#12
Thomas Scodellaro, Jane M McKenzie, Yves d'Udekem, Warwick Butt, Siva P Namachivayam
OBJECTIVES: To identify the prevalence, causes, risk factors, and outcomes associated with extubation failure following first stage single ventricle reconstruction surgery. DESIGN: Retrospective cohort analysis of neonates who underwent a first stage single ventricle reconstruction operation. Extubation failure was defined as endotracheal reintubation within 48 hours of first extubation attempt. SETTING: The Royal Children's Hospital, Melbourne...
September 15, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28922260/increased-risk-of-inflammatory-bowel-disease-in-a-population-based-cohort-study-of-patients-with-hirschsprung-disease
#13
Anna Löf Granström, Leila Amin, Henrik Arnell, Tomas Wester
OBJECTIVES: Hirschsprung disease (HSCR) has previously been associated with inflammatory bowel disease (IBD). There are no data to show how common this association is. The aim of this study was to assess the risk of IBD in individuals with HSCR in a population-based cohort. METHODS: This was a nationwide, population-based cohort study. The study exposure was HSCR and the study outcome was IBD. The cohort included all individuals with HSCR registered in the Swedish National Patient Register between 1964-2013 and ten age- and sex-matched controls per patient, randomly selected from the Swedish Population Register...
September 16, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28922257/endoscopic-and-histological-assessment-of-paediatric-inflammatory-bowel-disease-over-a-three-year-follow-up-period
#14
J J Ashton, Q Bonduelle, E Mossotto, T Coelho, A Batra, N A Afzal, B Vadgama, S Ennis, R M Beattie
OBJECTIVES: Discrepancies between Inflammatory bowel disease (IBD) endoscopic/histological extent are documented at diagnosis. It is unclear whether these differences persist through disease course, with potential impact on categorisation and management. We aimed to analyse the progression of disease over a 3-year period. METHODS: Patients aged < 17 years, diagnosed between 2010-2013 at Southampton Children's Hospital and followed-up for 3 years were eligible...
September 16, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28922243/evaluation-of-the-changes-in-the-quality-of-life-in-patients-undergoing-orthognathic-surgery-a-multicenter-study
#15
Elham Sadat Emadian Razvadi, Sepideh Soheilifar, Mohammad Esmaeelinejad, Navid Naghdi
Orthognathic surgery can affect patients' quality of life. The aim of the present study was to assess changes in quality of life during combined orthodontics-surgery treatment and effect of orthodontist-surgeon teamwork on final patient's satisfaction. Twenty-six orthognathic patients who were referred to oral and maxillofacial department of 3 hospitals in Tehran were included in the study. Orthognathic quality of life questionnaire (OQLQ) was given to patients 1 week before, 4 weeks and 4 months after surgery...
September 15, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28922212/equity-of-physical-characteristics-between-adolescent-males-and-females-participating-in-single-or-mixed-gender-sport
#16
L M Krause, G A Naughton, A C Benson, S Tibbert
PURPOSE: Policies on single or mixed sex junior sports participation continue to be challenged publically and legally. Often challenges relate to perceptions of size and performance variability between adolescent males and females, yet the evidence base behind these challenges lacks recent review and rigor. METHODS: Physical performance was compared between males and females from two groups of younger (<13 years, n = 109, 67% females, 33% males) and older (>13 years, n = 108, 43% females, 57% males) adolescents...
September 12, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28922195/dispositional-mindful-attention-in-relation-to-negative-affect-tobacco-withdrawal-and-expired-carbon-monoxide-on-and-after-quit-day
#17
Daniel J Paulus, Kirsten J Langdon, David W Wetter, Michael J Zvolensky
BACKGROUND: Mindfulness (or "Mindful Attention") has been described as the presence or absence of attention to, and awareness of, what is occurring in the present moment. Among smokers, greater mindfulness is associated with greater effect stability and reduced cue-induced craving. While studies have shown that mindfulness is associated with other smoking-related factors such as reduced withdrawal symptoms using cross-sectional data, relatively little is known about the associations between baseline mindful attention and future abstinence-related effect/withdrawal...
September 15, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28922087/preexisting-cardiovascular-risk-and-subsequent-heart-failure-among-non-hodgkin-lymphoma-survivors
#18
Talya Salz, Emily C Zabor, Peter de Nully Brown, Susanne Oksberg Dalton, Nirupa J Raghunathan, Matthew J Matasar, Richard Steingart, Andrew J Vickers, Peter Svenssen Munksgaard, Kevin C Oeffinger, Christoffer Johansen
Purpose The use of anthracycline chemotherapy is associated with heart failure (HF) among survivors of non-Hodgkin lymphoma (NHL). We aimed to understand the contribution of preexisting cardiovascular risk factors to HF risk among NHL survivors. Methods Using Danish registries, we identified adults diagnosed with aggressive NHL from 2000 to 2010 and sex- and age-matched general-population controls. We assessed HF from 9 months after diagnosis through 2012. We used Cox regression analysis to assess differences in risk for HF between survivors and general population controls...
September 18, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28922006/process-factors-explaining-psycho-social-outcomes-in-adventure-therapy
#19
Keith C Russell, Harold L Lee Gillis, Dennis M Kivlighan
The development and factor analysis of the Adventure Therapy Experience Scale (ATES) is the first attempt found in the literature to empirically and quantitatively identify therapeutic factors theorized to affect change in the adventure therapy experience (Russell & Gillis, 2017). This study utilizes the ATES to explore how its inherent factors may impact treatment outcome utilizing a routine outcome monitoring process to empirically test how these factors may contribute to treatment outcome over time. The sample of 168 males 21...
September 2017: Psychotherapy
https://www.readbyqxmd.com/read/28921903/risk-factors-for-postoperative-ileus-after-colorectal-cancer-surgery
#20
E G Rybakov, Y A Shelygin, E A Khomyakov, I V Zarodniuk
AIM: To assess the rate and independent risk factors of postoperative ileus (POI) after colorectal cancer surgery. METHODS: Three hundred consecutive patients underwent colorectal surgery for cancer at the State Scientific Centre of coloproctology, Moscow, Russia, between November 2015 and August 2016. POI was diagnosed as an absence of intestinal function for 72 hours or more after operation and confirmed by plain radiography. Uni- and multivariate logistic regression of the tumour-, patient- and treatment-related factors was performed...
September 16, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
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