keyword
https://read.qxmd.com/read/38537227/presentation-of-wernicke-encephalopathy-in-patient-secondary-to-one-anastomosis-gastric-bypass-case-report-and-literature-review
#1
JOURNAL ARTICLE
Luis F Zorrilla-Núñez, Luis Tamez-Pedroza, Patricio Durán-Moreno, Gerardo E Muñoz-Maldonado
Wernicke encephalopathy, which is caused by a thiamine deficiency, occurs in 0.8-2% of the population. Only 16% present the typical triad of this disease: nystagmus, confusion and ataxia. We present the case of a postoperative patient with a one anastomosis gastric bypass with reoperation undergoing a Roux-en-Y gastric bypass that begins with confusion and nystagmus on her third postoperative day. The diagnosis of Wernicke encephalopathy is made by imaging, and vitamin B1 is administered with total improvement of nystagmus and altered state of consciousness (lethargy, bradypsychia, bradylalia)...
2024: Cirugia y Cirujanos
https://read.qxmd.com/read/38527735/use-of-thiamine-supplementation-in-pregnant-women-diagnosed-with-hyperemesis-gravidarum-and-wernicke-encephalopathy
#2
JOURNAL ARTICLE
Angela Feagan Clark
Hyperemesis gravidarum is the most common condition requiring hospital care for women during the first 20 weeks of pregnancy and may lead to malnutrition, dehydration, and vitamin deficiencies. Depletion of vitamins such as thiamine may result in the development of Wernicke encephalopathy, a severe neurological disorder that can increase the risk for mortality and morbidity for the mother and fetus. A lack of awareness regarding the relationship of hyperemesis gravidarum and Wernicke encephalopathy may result in delayed treatment and disease management...
March 22, 2024: Nursing for Women's Health
https://read.qxmd.com/read/38526684/vitamin-b12-deficiency-induced-megaloblastic-anemia-in-a-pediatric-patient-with-autism-spectrum-disorder-with-a-chronically-unbalanced-diet
#3
JOURNAL ARTICLE
Yuri Sawada, Kenichi Sakamoto, Atsushi Tsukamura, Chihiro Sawai
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by a lack of behavioral flexibility and stereotyped language. Food selectivity is common among children with ASD because of their persnickety nature. A prolonged unbalanced diet results in an increased risk of several diseases, such as iron deficiency anemia, scurvy, rickets, dry eye, and Wernicke encephalopathy. However, no cases of megaloblastic anemia have been reported to date. We report the case of an 11-year-old boy with ASD who developed megaloblastic anemia due to vitamin B12 deficiency...
March 25, 2024: International Journal of Hematology
https://read.qxmd.com/read/38521679/cortico-cortical-evoked-potentials-of-language-tracts-in-minimally-invasive-glioma-surgery-guided-by-penfield-stimulation
#4
JOURNAL ARTICLE
Kathleen Seidel, Jonathan Wermelinger, Pablo Alvarez-Abut, Vedran Deletis, Andreas Raabe, David Zhang, Philippe Schucht
OBJECTIVE: We investigated the feasibility of recording cortico-cortical evoked potentials (CCEPs) in patients with low- and high-grade glioma. We compared CCEPs during awake and asleep surgery, as well as those stimulated from the functional Broca area and recorded from the functional Wernicke area (BtW), and vice versa (WtB). We also analyzed CCEP properties according to tumor location, histopathology, and aphasia. METHODS: We included 20 patients who underwent minimally invasive surgery in an asleep-awake-asleep setting...
March 5, 2024: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/38520815/vitamin-deficiencies-in-children-lessons-from-clinical-and-neuroimaging-findings
#5
JOURNAL ARTICLE
Gabrielle Dupuy, Charles-Joris Roux, Rémi Barrois, Apolline Imbard, Clément Pontoizeau, Marie Thérèse Dangles, Mélodie Aubart, Jean-Baptiste Arnoux, Diane Margoses, Anaïs Brassier, Clothilde Marbach, Claire-Marine Bérat, Eugénie Sarda, Cyril Gitiaux, Pascale de Lonlay, Nathalie Boddaert, Manuel Schiff, Isabelle Desguerre
BACKGROUND AND AIMS: Water-soluble vitamins play an essential coenzyme role in the nervous system. Acquired vitamin deficiencies are easily treatable, however, without treatment, they can lead to irreversible complications. This study aimed to provide clinical, laboratory parameters and neuroimaging data on vitamin deficiencies in an attempt to facilitate early diagnosis and prompt supplementation. METHODS: From July 1998 to July 2023, patients at Necker-Enfants-Malades Hospital presenting with acute neurological symptoms attributed to acquired vitamin deficiency were included...
February 26, 2024: European Journal of Paediatric Neurology: EJPN
https://read.qxmd.com/read/38501383/conversational-production-and-comprehension-fmri-evidence-reminiscent-of-but-deviant-from-the-classical-broca-wernicke-model
#6
JOURNAL ARTICLE
Caroline Arvidsson, Ekaterina Torubarova, André Pereira, Julia Uddén
A key question in research on the neurobiology of language is to which extent the language production and comprehension systems share neural infrastructure, but this question has not been addressed in the context of conversation. We utilized a public fMRI dataset where 24 participants engaged in unscripted conversations with a confederate outside the scanner, via an audio-video link. We provide evidence indicating that the two systems share neural infrastructure in the left-lateralized perisylvian language network, but diverge regarding the level of activation in regions within the network...
March 1, 2024: Cerebral Cortex
https://read.qxmd.com/read/38500607/stability-of-vitamin-a-at-critical-points-in-pet-feed-manufacturing-and-during-premix-storage
#7
JOURNAL ARTICLE
Gabriela Miotto Galli, Ines Andretta, Nicolas Martinez, Bruno Wernick, Yauheni Shastak, Alvaro Gordillo, Jaqueline Gobi
The objective of this research was to assess and quantify the potential vitamin A losses that occur during the manufacturing of pet feed and premix, as well as during their extended storage periods. This trial was conducted at a commercial feeder mill that utilized a standard commercial dog feed along with a corresponding vitamin-mineral premix. The calculated amount of vitamin A supplemented in the feed, in addition to the endogenous vitamins present in the ingredients, was adjusted to 18,000 IU/kg of feed...
2024: Frontiers in Veterinary Science
https://read.qxmd.com/read/38469004/rehabilitation-strategies-for-wernicke-korsakoff-syndrome-physiotherapy-interventions-and-management-approaches
#8
Ghanishtha C Burile, Neha Arya, Nikita H Seth, Tejaswini Fating
Korsakoff syndrome and Wernicke's encephalopathy (WE) show neurological and cognitive deficits. Wernicke-Korsakoff syndrome (WKS) is a compound neurological condition. The cause of this neurological condition could be the consumption of alcohol regularly for a chronic duration. A tailored rehabilitation protocol that focuses on cognitive and physical deficiencies was implemented along with thiamine supplementation for managing a case of a 49-year-old male patient who had a history of high alcohol consumption and was exhibiting typical signs of WKS...
February 2024: Curēus
https://read.qxmd.com/read/38465188/the-role-of-early-rehabilitation-in-better-outcomes-in-a-rare-presentation-of-tuberculous-meningitis-with-broca-s-aphasia
#9
Ghanishtha C Burile, Pallavi Harjpal, Neha P Arya, Nikita H Seth
There is a complex link between tuberculous meningitis (TBM) and aphasia, in which a language impairment is caused by an injury to the cortical language centre. The parts of the brain that function for speech and language production are the Wernicke's, Broca's, and arcuate fasciculus regions. This case report mainly highlights the neurological consequences of TBM, and how it affects language and speech functioning. It outlines a comprehensive physiotherapy rehabilitation program that targets a range of issues for the patient, such as verbal output, weakness, motor deficits, articulation issues in speech, and coordination issues...
February 2024: Curēus
https://read.qxmd.com/read/38463520/letter-to-the-editor-total-parenteral-nutrition-induced-wernicke-s-encephalopathy-after-oncologic-gastrointestinal-surgery
#10
JOURNAL ARTICLE
Oguzhan Koca, Zeynep Hande Turna
No abstract text is available yet for this article.
2024: Open Medicine (Warsaw, Poland)
https://read.qxmd.com/read/38449490/seizures-in-the-third-trimester-of-pregnancy-a-rare-case-of-wernicke-s-encephalopathy-mimicking-eclampsia
#11
Badra Bannour, Maroi Baazaoui, Maroi Bannour, Imen Bannour, Hiba Abdellaoui, Khaled Ben Jazia
Unless otherwise demonstrated, seizures during pregnancy that happen after 20 weeks of gestation are typically caused by eclampsia. In our clinical case we report the diagnostic challenge of Wernicke's encephalopathy occurring at 34 weeks and mimicking an eclamptic attack. This is about a 30-year-old female patient who suffers from hyperemesis gravidarum during her pregnancy. she has no known history of epilepsy .The patient was brought to the emergency room by medical transport at 34 weeks of gestation due to a seizure at home...
May 2024: Radiology Case Reports
https://read.qxmd.com/read/38449424/altered-mental-status-and-cardiac-failure-due-to-thiamine-deficiency-in-an-overweight-teen
#12
JOURNAL ARTICLE
Brittany M Slagle, Trevor Meece, Claire Foster, Andrew Campbell, Lauren Tong, Paul Drake
We describe an overweight but otherwise previously healthy 17-year-old female who presented with altered mental status and rapidly progressive weakness. She was ultimately diagnosed with Wernicke encephalopathy and wet beriberi resulting from severe thiamine deficiency. She required admission to the pediatric ICU because of hypoventilation with progressive weakness and worsening encephalopathy and was found to have impaired cardiac function as assessed by echocardiography. Her heart function and encephalopathy improved on initiation of thiamine repletion...
March 7, 2024: Pediatrics
https://read.qxmd.com/read/38421595/the-role-of-cognitive-control-and-naming-in-aphasia
#13
JOURNAL ARTICLE
Annamária Kiss, Valéria Csépe
The classical aphasia literature has placed considerable emphasis on the language-centered understanding of aphasia and failed to consider the role of executive functions (EFs) regarding different aspects of patients' performance. Many current studies suggest deficits in EFs in individuals with aphasia, however, the available data is still limited. Here, our aim was to investigate the impairment of EFs and its potential negative effects on naming (slower performance, increased reaction time and/or decreased accuracy)...
February 29, 2024: Biologia futura
https://read.qxmd.com/read/38420944/safety-and-efficacy-of-switching-sar341402-insulin-aspart-and-originator-insulin-aspart-vs-continuous-use-of-originator-insulin-aspart-in-adults-with-type-1-diabetes-the-gemelli-x-trial
#14
JOURNAL ARTICLE
Viral N Shah, Amer Al-Karadsheh, Cathy Barnes, Jose Mandry, Samer Nakhle, Karin Wernicke-Panten, Daniel Kramer, Wolfgang Schmider, Suzanne Pierre, Lenore Teichert, Baerbel Rotthaeuser, Bhaswati Mukherjee, Timothy S Bailey
BACKGROUND: SAR341402 insulin aspart (SAR-Asp) is a rapid-acting insulin analog developed as an interchangeable biosimilar to the marketed insulin aspart reference product (NovoLog; NN-Asp). GEMELLI X was a randomized controlled trial to assess outcomes with a biosimilar in line with the US Food and Drug Administration requirements for designation as an interchangeable biosimilar. This report assessed whether multiple switches between SAR-Asp and NN-Asp lead to equivalent safety and efficacy compared with continuous use of NN-Asp in adults with type 1 diabetes (T1D) treated with multiple daily injections, using once-daily insulin glargine U100 (Lantus) as the basal insulin...
February 29, 2024: Journal of Diabetes Science and Technology
https://read.qxmd.com/read/38417935/nystagmus-in-a-child-with-nephrotic-syndrome
#15
JOURNAL ARTICLE
Hamsa Vasantha Shekar Reddy, Divya S Nagabushana, Deepthi Kattamanchi, Ahish Dakappa
We report a child with steroid-dependent nephrotic syndrome presenting with excessive irritability, double vision and inability to walk for 5 days. On examination, the child was irritable with Glasgow coma sccale (GCS of 12/15, had bilateral convergent squint (R>L), vertical nystagmus, ataxia without any focal neurological deficits and normal fundus. MRI brain with venogram showed bilateral symmetric FLAIR hyperintensity in the medial thalamus and periaqueductal grey matter showing diffuse restriction with normal venogram...
February 27, 2024: BMJ Case Reports
https://read.qxmd.com/read/38417618/carl-wernicke-of-wernicke-s-area-a-historical-review
#16
REVIEW
Abdullah Ahmad, Nitin Jagdhane, Karin Ademmer, Kishor Choudhari
Wernicke's area, also known as Brodmann area 22, is located in the posterior segment of the superior temporal gyrus in the dominant hemisphere. Carl Wernicke, a German neurologist, described this area in 1874. The life story of Carl Wernicke, a 19th century medical genius, remains an inspiration for all neuroscientists even a hundred years later. The authors outline Wernicke's life story and academic achievements in the fields of neurosurgery, neurology, and psychiatry. We explore his remarkable ability to turn his many setbacks into steps forward, his controversial foray into psychiatry, and his wide-ranging set of contributions including: his work on external ventricular drainage for hydrocephalus; encephalopathy; his description of the eponymous Wernicke's area; and his field-defining work on aphasia...
February 26, 2024: World Neurosurgery
https://read.qxmd.com/read/38415422/-hyperemesis-gravidarum-leading-to-gayet-wernicke-encephalopathy
#17
JOURNAL ARTICLE
Amine Bentahar, Taoufik Boubga, Habib Bellamlih, Khalil Chafi, Monsif Salek, Soufiane Belabbes, Brahim Zinoun, Taoufik Africha
No abstract text is available yet for this article.
February 2024: La Revue du Praticien
https://read.qxmd.com/read/38404781/brain-functional-connectivity-alterations-of-wernicke-s-area-in-individuals-with-autism-spectrum-conditions-in-multi-frequency-bands-a-mega-analysis
#18
JOURNAL ARTICLE
Linlin Zhan, Yanyan Gao, Lina Huang, Hongqiang Zhang, Guofeng Huang, Yadan Wang, Jiawei Sun, Zhou Xie, Mengting Li, Xize Jia, Lulu Cheng, Yang Yu
Characterized by severe deficits in communication, most individuals with autism spectrum conditions (ASC) experience significant language dysfunctions, thereby impacting their overall quality of life. Wernicke's area, a classical and traditional brain region associated with language processing, plays a substantial role in the manifestation of language impairments. The current study carried out a mega-analysis to attain a comprehensive understanding of the neural mechanisms underpinning ASC, particularly in the context of language processing...
February 29, 2024: Heliyon
https://read.qxmd.com/read/38403010/tdcs-of-right-hemispheric-wernicke-s-area-homologue-affects-contextual-learning-of-novel-lexicon
#19
JOURNAL ARTICLE
Daria Gnedykh, Diana Tsvetova, Nadezhda Mkrtychian, Evgeny Blagovechtchenski, Svetlana Kostromina, Yury Shtyrov
Numerous studies have shown robust evidence of the right hemisphere's involvement in language comprehension, for instance in the processing of intonation, grammar, prelexical processing stages, novel metaphor comprehension, etc. However, its role in lexicon acquisition remains obscure. We applied transcranial direct current stimulation (tDCS) over the right-hemispheric homologue of Wernicke's area to assess its putative involvement in processing different types of novel semantics. After receiving 15 min of anodal, cathodal, or sham (placebo) tDCS, three groups of healthy participants learnt novel concrete and abstract words in the context of short stories...
February 23, 2024: Neurobiology of Learning and Memory
https://read.qxmd.com/read/38392959/the-effects-of-intensive-rehabilitation-combined-with-thiamine-treatment-on-cognitive-recovery-in-a-case-of-non-alcoholic-wernicke-korsakoff-syndrome
#20
Cinzia Palmirotta, Gilda Turi, Serena Tagliente, Michele Pansini, Stefania De Trane, Gianvito Lagravinese
Wernicke-Korsakoff Syndrome (WKS) is a severe neurological disorder resulting from thiamine deficiency, commonly associated with alcohol consumption but also stemming from dietary imbalances or other clinical conditions. Cognitive deficits, affecting memory and executive functions, pose a serious concern, with partial recovery often not complete. A 28-year-old woman underwent surgery for acute necrotizing hemorrhagic pancreatitis, leading to admission for post-acute intensive treatment due to prolonged bed rest syndrome...
February 14, 2024: Neurology International
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