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https://www.readbyqxmd.com/read/29352711/gold-cleaning-methods-for-preparation-of-cell-culture-surfaces-for-self-assembled-monolayers-of-zwitterionic-oligopeptides
#1
Junko Enomoto, Tatsuto Kageyama, Dina Myasnikova, Kisaki Onishi, Yuka Kobayashi, Yoko Taruno, Takahiro Kanai, Junji Fukuda
Self-assembled monolayers (SAMs) have been used to elucidate interactions between cells and material surface chemistry. Gold surfaces modified with oligopeptide SAMs exhibit several unique characteristics, such as cell-repulsive surfaces, micropatterns of cell adhesion and non-adhesion regions for control over cell microenvironments, and dynamic release of cells upon external stimuli under culture conditions. However, basic procedures for the preparation of oligopeptide SAMs, including appropriate cleaning methods of the gold surface before modification, have not been fully established...
January 15, 2018: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/29352568/dual-energy-computed-tomography-should-be-a-first-line-preoperative-localization-imaging-test-for-primary-hyperparathyroidism-patients
#2
Jake Hiebert, Cameron Hague, Shangmei Hou, Sam M Wiseman
BACKGROUND: The objective of this study was to evaluate the performance of dual-energy computed tomography (DECT) for preoperative parathyroid tumor (PT) localization in primary hyperparathyroid (PHP) patients. METHODS: A retrospective review was carried out of the medical records of all PHP patients who underwent ultrasound (US), Tc-99m sestamibi noncontrast single photon emission computed tomography (CT-MIBI), DECT and parathyroidectomy at a single center. RESULTS: The sensitivities and accuracies for preoperative PT localization in the 97 patient study population were: US 40% and 93%, CT-MIBI 64...
January 5, 2018: American Journal of Surgery
https://www.readbyqxmd.com/read/29349431/complete-robotic-repair-of-a-renal-artery-aneurysm
#3
Kira Long, Jonathan Silberstein, Raju Thomas, Ashlie White, Jack Hua, Albert D Sam
Although the majority of renal artery aneurysms require only observation, those that require treatment have been addressed primarily surgically or endovascularly. We report a case of surgical resection of a large, symptomatic renal artery aneurysm from an entirely robotic approach.
December 2017: Journal of Vascular Surgery Cases and Innovative Techniques
https://www.readbyqxmd.com/read/29349054/post-traumatic-peripheral-giant-osteoma-in-the-frontal-bone
#4
Seong Hwan Kim, Dong Seob Lim, Do Hun Lee, Kyung Pil Kim, Jae Ha Hwang, Kwang Seog Kim, Sam Yong Lee
Osteomas are benign, slow-growing tumors that most frequently occur in the craniomaxillofacial region. These tumors are mostly asymptomatic and are generally found incidentally. A giant osteoma is generally considered to be greater than 30 mm in diameter or 110 g in weight. A 35-year-old female presented to us with complaints of a firm mass that showed continuous growth on the forehead following trauma. A hairline incision was made to expose the osteoma. Biopsy of the tumor confirmed a osteoma. There were no complications after surgery...
December 2017: Archives of Craniofacial Surgery
https://www.readbyqxmd.com/read/29349011/middle-glenohumeral-ligament-abrasion-causing-upper-subscapularis-tear
#5
Paul C Brady, Heather Grubbs, Alexandre Lädermann, Christopher R Adams
The middle glenohumeral ligament (MGHL) typically contributes partially to the anterior stability of the shoulder. In a very limited number of cases, the MGHL can cause abrasion on the upper edge of the subscapularis causing persistent pain symptoms for patients. The condition is exacerbated by internal rotation of the arm. In this Technical Note, we describe this entity and call it the SAM lesion (Subscapularis Abrasion from the MGHL). We present a technique of addressing this lesion.
December 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/29348638/changes-in-cytokine-responses-to-tb-antigens-esat-6-cfp-10-and-tb-7-7-and-inflammatory-markers-in-peripheral-blood-during-therapy
#6
Ah Young Leem, Joo Han Song, Eun Hye Lee, Hyejon Lee, Bora Sim, Song Yee Kim, Kyung Soo Chung, Eun Young Kim, Ji Ye Jung, Moo Suk Park, Young Sam Kim, Joon Chang, Young Ae Kang
Multiple cytokines and inflammatory markers control TB infection. We aimed to investigate the changes in multiple cytokines and inflammatory markers in active TB patients following anti-TB drug therapy. Twenty-nine patients with active TB were recruited prospectively between December 2010 and July 2017. Blood samples were collected before (T0), after 2 months (T2), and at the end of anti-TB treatment (Tend). We measured the levels of Interferon (IFN)-γ, interleukin (IL)-2, IL-12, IL-10, IL-13 and tumor necrosis factor (TNF)-α in supernatants collected from the QuantiFERON-TB Gold In-Tube assay (QFT-GIT), as well as the WBC, neutrophil, platelet count and neutrophil to lymphocyte ratio (NLR) in whole blood...
January 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29348582/nanostructured-titanium-surfaces-exhibit-recalcitrance-towards-staphylococcus-epidermidis-biofilm-formation
#7
Yunyi Cao, Bo Su, Subash Chinnaraj, Saikat Jana, Leon Bowen, Sam Charlton, Pengfei Duan, Nicholas S Jakubovics, Jinju Chen
Titanium-based implants are ubiquitous in the healthcare industries and often suffer from bacterial attachment which results in infections. An innovative method of reducing bacterial growth is to employ nanostructures on implant materials that cause contact-dependent cell death by mechanical rupture of bacterial cell membranes. To achieve this, we synthesized nanostructures with different architectures on titanium surfaces using hydrothermal treatment processes and then examined the growth of Staphylococcus epidermidis on these surfaces...
January 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29348140/interactions-localization-and-phosphorylation-of-the-m6a-generating-mettl3-mettl14-wtap-complex
#8
Eva Schöller, Franziska Weichmann, Thomas Treiber, Sam Ringle, Nora Treiber, Andrew Flatley, Regina Feederle, Astrid Bruckmann, Gunter Meister
N6-methyladenine (m6A) is found on many eukaryotic RNAs including mRNAs. M6A modification has been implicated in mRNA stability and turn over, localization or translation efficiency. A heterodimeric enzyme complex composed of METTL3 and METTL14 generates m6A on mRNAs. METTL3/14 is found in the nucleus where it is localized to nuclear speckles and the splicing regulator WTAP is required for this distinct nuclear localization pattern. Although recent crystal structures revealed how the catalytic MT-A70 domains of METTL3 and METTL14 interact with each other, a more global architecture including WTAP and RNA interactions has not been reported so far...
January 18, 2018: RNA
https://www.readbyqxmd.com/read/29346416/decoding-the-network-of-trypanosoma-brucei-proteins-that-determines-sensitivity-to-apolipoprotein-l1
#9
Rachel B Currier, Anneli Cooper, Hollie Burrell-Saward, Annette MacLeod, Sam Alsford
In contrast to Trypanosoma brucei gambiense and T. b. rhodesiense (the causative agents of human African trypanosomiasis), T. b. brucei is lysed by apolipoprotein-L1 (apoL1)-containing human serum trypanolytic factors (TLF), rendering it non-infectious to humans. While the mechanisms of TLF1 uptake, apoL1 membrane integration, and T. b. gambiense and T. b. rhodesiense apoL1-resistance have been extensively characterised, our understanding of the range of factors that drive apoL1 action in T. b. brucei is limited...
January 18, 2018: PLoS Pathogens
https://www.readbyqxmd.com/read/29346366/testing-for-soil-transmitted-helminth-transmission-elimination-analysing-the-impact-of-the-sensitivity-of-different-diagnostic-tools
#10
Marleen Werkman, James E Wright, James E Truscott, Alice V Easton, Rita G Oliveira, Jaspreet Toor, Alison Ower, Kristjana H Ásbjörnsdóttir, Arianna R Means, Sam H Farrell, Judd L Walson, Roy M Anderson
In recent years, an increased focus has been placed upon the possibility of the elimination of soil-transmitted helminth (STH) transmission using various interventions including mass drug administration. The primary diagnostic tool recommended by the WHO is the detection of STH eggs in stool using the Kato-Katz (KK) method. However, detecting infected individuals using this method becomes increasingly difficult as the intensity of infection decreases. Newer techniques, such as qPCR, have been shown to have greater sensitivity than KK, especially at low prevalence...
January 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29346280/a-multi-band-body-worn-distributed-radio-frequency-exposure-meter-design-on-body-calibration-and-study-of-body-morphology
#11
Reza Aminzadeh, Arno Thielens, Sam Agneessens, Patrick Van Torre, Matthias Van den Bossche, Stefan Dongus, Marloes Eeftens, Anke Huss, Roel Vermeulen, René de Seze, Paul Mazet, Elisabeth Cardis, Hendrik Rogier, Martin Röösli, Luc Martens, Wout Joseph
A multi-band Body-Worn Distributed exposure Meter (BWDM) calibrated for simultaneous measurement of the incident power density in 11 telecommunication frequency bands, is proposed. The BDWM consists of 22 textile antennas integrated in a garment and is calibrated on six human subjects in an anechoic chamber to assess its measurement uncertainty in terms of 68% confidence interval of the on-body antenna aperture. It is shown that by using multiple antennas in each frequency band, the uncertainty of the BWDM is 22 dB improved with respect to single nodes on the front and back of the torso and variations are decreased to maximum 8...
January 18, 2018: Sensors
https://www.readbyqxmd.com/read/29346204/new-diabetes-medications-raise-new-perioperative-concerns-for-the-anesthesiologist
#12
Jennifer A DeCou, Stephen H Sams
No abstract text is available yet for this article.
February 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29345980/society-of-biomolecular-imaging-and-informatics-high-content-screening-high-content-analysis-emerging-technologies-in-biological-models-when-and-why
#13
Ann F Hoffman, John Nolan, David F Gebhard, Debra Nickischer, Wienand Omta, Sam Cooper, Sharon Presnell, Judi Wardwell-Swanson, Myles Fennell
No abstract text is available yet for this article.
January 2018: Assay and Drug Development Technologies
https://www.readbyqxmd.com/read/29345067/supramolecular-gels-derived-from-the-salts-of-variously-substituted-phenylacetic-acid-and-dicyclohexyl-amine-design-synthesis-structures-and-dye-adsorption
#14
Parthasarathi Dastidar, Rajdip Roy, Tapas Kumar Adalder
A well-studied supramolecular synthon namely secondary ammonium monocarboxylate (SAM) was exploited to generate a new series of organic salts derived from variously substituted phenylacetic acid (PA) and dicyclohexyl amine (DCA) as potential low molecular weight gelators (LMWGs). As much as 25% of the SAM salts under study were gelators. The gels were characterized by rheology and the morphology of the gel networks was studied by high resolution electron microscopy. Single crystal and powder X-ray diffraction data were employed to study structure-property (gelation) correlation...
January 18, 2018: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/29344549/e-cadherin-and-k-ras-implications-of-a-newly-developed-model-of-gastric-cancer
#15
EDITORIAL
Jacob E Till, Sam S Yoon, Sandra Ryeom
No abstract text is available yet for this article.
November 2017: Oncoscience
https://www.readbyqxmd.com/read/29343916/effects-of-tumor-size-and-location-on-survival-in-upper-tract-urothelial-carcinoma-after-nephroureterectomy
#16
Shreyas S Joshi, Laura L Quast, Sam S Chang, Sanjay G Patel
Introduction: Upper Tract Urothelial Carcinoma (UTUC) is a rare disease with few prognostic determinants. We sought to evaluate the impact of tumor size and location on patient survival following nephroureterectomy for UTUC. Materials and Methods: Data on 8284 patients treated with radical nephroureterectomy for UTUC in the United States between 1998 and 2011 were analyzed from the National Cancer Data Base. Univariable survivorship curves were generated based on pT stage, pN stage, grade, tumor size, and tumor site (renal pelvis vs...
January 2018: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/29343446/s-adenosyl-methionine-prevents-asd-like-behaviors-triggered-by-early-postnatal-valproic-acid-exposure-in-very-young-mice
#17
Asher Ornoy, Liza Weinstein-Fudim, Matanel Tfilin, Zivanit Ergaz, Joseph Yanai, Moshe Szyf, Gadi Turgeman
INTRODUCTION: A common animal model of ASD is the one induced by valproic acid (VPA), inducing epigenetic changes and oxidative stress. We studied the possible preventive effect of the methyl donor for epigenetic enzymatic reactions, S-adenosine methionine (SAM), on ASD like behavioral changes and on redox potential in the brain and liver in this model. METHODS: ICR albino mice were injected on postnatal day 4 with one dose of 300 mg/kg of VPA, with normal saline (controls) or with VPA and SAM that was given orally for 3 days at the dose of 30 mg/kg body weight...
January 14, 2018: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/29343166/consensus-statement-of-the-international-summit-on-intellectual-disability-and-dementia-on-valuing-the-perspectives-of-persons-with-intellectual-disability
#18
Karen Watchman, Matthew P Janicki, Leslie Udell, Mary Hogan, Sam Quinn, Anna Beránková
The International Summit on Intellectual Disability and Dementia covered a range of issues related to dementia and intellectual disability, including the dearth of personal reflections of persons with intellectual disability affected by dementia. This article reflects on this deficiency and explores some of the personal perspectives gleaned from the literature, from the Summit attendees and from the experiences of persons with intellectual disability recorded or scribed in advance of the two-day Summit meeting...
January 1, 2018: Journal of Intellectual Disabilities: JOID
https://www.readbyqxmd.com/read/29342441/improving-professionalism-between-radiology-and-emergency-medicine
#19
Kenny Q Sam, Larry Laufman, Sara Andrabi, Peter N Fata, Megan K McNeer, Pedro Diaz-Marchan, Ellen Friedman
No abstract text is available yet for this article.
January 13, 2018: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29342126/tailoring-cu-nanoparticle-catalyst-for-methanol-synthesis-using-the-spinning-disk-reactor
#20
Christian Ahoba-Sam, Kamelia V K Boodhoo, Unni Olsbye, Klaus-Joachim Jens
Cu nanoparticles are known to be very active for methanol (MeOH) synthesis at relatively low temperatures, such that smaller particle sizes yield better MeOH productivity. We aimed to control Cu nanoparticle (NP) size and size distribution for catalysing MeOH synthesis, by using the spinning disk reactor. The spinning disk reactor (SDR), which operates based on shear effect and plug flow in thin films, can be used to rapidly micro-mix reactants in order to control nucleation and particle growth for uniform particle size distribution...
January 17, 2018: Materials
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