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https://www.readbyqxmd.com/read/28630242/tumour-necrosis-factor-tnf-inhibitor-induced-isolated-pleural-granulomas-a-rare-adverse-effect
#1
Muhammad Sajawal Ali, Rose Franco, Dheeraj Dhotre, Nagarjun Rao
A 53-year-old man with a history of Crohn's disease on infliximab, presented with several weeks of cough and dyspnoea. He had a right-sided pleural effusion, found to be exudative with lymphocytic predominance. He underwent right-sided video-assisted thoracic surgery (VATS) with biopsies and pleurodesis. Histopathology showed pleural-based non-caseating granulomas with unremarkable lung parenchyma. Cultures were only positive for Propionibacterium acnes 8 months later, he was found to have a left-sided exudative, lymphocytic predominant pleural effusion...
June 18, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28619528/ineffective-cough-and-mechanical-mucociliary-clearance-techniques
#2
A Fernández-Carmona, L Olivencia-Peña, M E Yuste-Ossorio, L Peñas-Maldonado
Cough is a fundamental defense mechanism for keeping the airway free of foreign elements. Life-threatening situations may arise when cough proves ineffective as a result of muscle weakness or altered mucociliary function. When a patient is unable to cough effectively, techniques are required to either reinforce or replace cough capacity. The use of mechanical systems that facilitate or substitute cough function is increasingly common in Intensive Care Units, where it is relatively frequent to find situations of ineffective cough due to different clinical causes...
June 12, 2017: Medicina Intensiva
https://www.readbyqxmd.com/read/28602999/cough-and-bronchiectasis
#3
REVIEW
Paul McCallion, Anthony De Soyza
Bronchiectasis is a chronic lung disease with permanent airway dilatation, mucus retention and recurrent lower respiratory tract infections. Bronchiectasis is increasing in prevalence and has a significant morbidity and an excess mortality rate over age matched controls. It is increasingly identified during investigations into chronic cough and is evident high resolution CT scanning. There remain significant knowledge gaps in our understanding of the epidemiology, pathophysiology, prognosis and optimal treatments in bronchiectasis...
June 7, 2017: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28601173/children-with-cough-and-fever-up-to-date-imaging-evaluation-and-management
#4
REVIEW
Gary R Schooler, Joseph T Davis, Victoria M Parente, Edward Y Lee
Cough and fever in infants and children are frequent but nonspecific symptoms. Several usual differential diagnoses are under consideration and imaging is often necessary to help arrive at an accurate diagnosis and ensure proper management. A broad spectrum of underlying disorders may be present. Radiologists must remain cognizant of the potential for immune dysfunction and underlying structural abnormalities. A clear understanding of up-to-date imaging evaluation recommendations and characteristic imaging features can assist radiologists and clinicians in arriving at the most accurate diagnosis in a timely manner and help ensure proper management and necessary follow-up imaging assessment...
July 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/28597697/effectiveness-of-assisted-and-unassisted-cough-capacity-in-amyotrophic-lateral-sclerosis-patients
#5
Jesús Sancho, Emilio Servera, Pilar Bañuls, Julio Marín
Decreased cough capacity during a respiratory infection is one of the main causes of acute respiratory failure and hospitalisation in amyotrophic lateral sclerosis (ALS). OBJECTIVE: To determine whether a respiratory measurement could identify the effectiveness of cough capacity in ALS during a respiratory infection. METHODS: This was a prospective study of all ALS patients who were treated at a respiratory care unit due to a respiratory infection from 2012 to 2016...
June 9, 2017: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
https://www.readbyqxmd.com/read/28566081/-a-rarely-isolated-bacterium-in-microbiology-laboratories-streptococcus-uberis
#6
Canan Eryıldız, Şebnem Bukavaz, Şaban Gürcan, Osman Hatipoğlu
Streptococcus uberis is a gram-positive bacterium that is mostly responsible for mastitis in cattle. The bacterium rarely has been associated with human infections. Conventional phenotyphic methods can be inadequate for the identification of S.uberis; and in microbiology laboratories S.uberis is confused with the other streptococci and enterococci isolates. Recently, molecular methods are recommended for the accurate identification of S.uberis isolates. The aim of this report is to present a lower respiratory tract infection case caused by S...
April 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28554579/wall-suction-assisted-image-guided-thoracentesis-a-safe-alternative-to-evacuated-bottles
#7
H Kim, P B Shyn, L Wu, V M Levesque, R Khorasani, S G Silverman
AIM: To compare the safety of evacuated bottle-assisted thoracentesis with wall suction-assisted thoracentesis. MATERIALS AND METHODS: An institutional review board-approved, Health Insurance Portability and Accountability Act-compliant retrospective study of 161 consecutive patients who underwent 191 evacuated bottle-assisted thoracenteses from 1 January 2012 to 30 September 2012, and 188 consecutive patients who underwent 230 wall suction-assisted thoracenteses from 1 January 2013 to 30 September 2013 was conducted...
May 26, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28538577/in-depth-review-of-symptoms-triggers-and-treatment-of-occipital-migraine-headaches-site-iv
#8
Mona Ascha, David E Kurlander, Abdus Sattar, James Gatherwright, Bahman Guyuron
BACKGROUND: This study reports the surgical technique and efficacy of deactivation of occipital-triggered migraine headaches. In addition, it reports the effect of surgical deactivation of occipital-triggered migraine headaches on migraine triggers and associated symptoms other than pain. METHODS: One hundred ninety-five patients undergoing surgery for occipital-triggered migraine headaches performed by a single surgeon, and followed for at least 1 year, were analyzed...
June 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28524084/bordetella-holmesii-lipid-a-structures-and-corresponding-genomic-sequences-comparison-in-three-clinical-isolates-and-the-reference-strain-atcc-51541
#9
Valérie Bouchez, Sami AlBitar-Nehmé, Alexey Novikov, Nicole Guiso, Martine Caroff
Bordetella holmesii can cause invasive infections but can also be isolated from the respiratory tract of patients with whooping-cough like symptoms. For the first time, we describe the lipid A structure of B. holmesii reference strain ATCC 51541 (alias NCTC12912 or CIP104394) and those of three French B. holmesii clinical isolates originating from blood (Bho1) or from respiratory samples (FR4020 and FR4101). They were investigated using chemical analyses, gas chromatography-mass spectrometry (GC-MS), and matrix-assisted laser desorption ionization-mass spectrometry (MALDI-MS)...
May 18, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28494216/cough-reflex-hypersensitivity-a-role-for-neurotrophins
#10
Ahmed Z El-Hashim, Sahar M Jaffal
Cough is one of the most common complaints for which sufferers seek medical assistance. However, currently available drugs are not very effective in treating cough, particularly that which follows an upper respiratory tract infection. Nonetheless, there has been a significant increase in our understanding of the mechanisms and pathways of the defensive cough as well as the hypersensitive/pathophysiological cough, both at airway and central nervous system (CNS) levels. Numerous molecules and signaling pathways have been identified as potential targets for antitussive drugs, including neurotrophins (NTs)...
March 2017: Experimental Lung Research
https://www.readbyqxmd.com/read/28489801/a-care-compliant-case-report-lung-transplantation-for-a-chinese-young-man-with-idiopathic-pleuroparenchymal-fibroelastosis
#11
Hui Huang, Ruie Feng, Shan Li, Bo Wu, Kai Xu, Zuojun Xu, Jingyu Chen
RATIONAL: Pleuroparenchymal fibroelastosis (PPFE) is a rare interstitial lung disease that is characterized radiologically by apical pleural thickening and histologically by elastic fibrosis of the visceral pleura. Although PPFE cases have been reported occasionally since this disease was initially described, most such cases have involved secondary PPFE. Idiopathic PPFE (iPPFE) cases have been less thoroughly studied. There are no effective medications for patients with iPPFE. PATIENT CONCERNS: A 34-year-old man with no asbestos or cigarette exposure was admitted to our ward due to worsening cough and exertional dyspnea for 10 years...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28477228/intrathecal-morphine-for-postoperative-pain-control-following-robot-assisted-prostatectomy-a-prospective-randomized-trial
#12
Junyeol Bae, Hyun-Chang Kim, Deok Man Hong
PURPOSE: Robot-assisted laparoscopic prostatectomy (RALP) is minimally invasive surgery, but also causes moderate to severe pain during the immediate postoperative period. We evaluated the efficacy and safety of intrathecal morphine (ITM) for postoperative pain control in patients undergoing RALP. METHODS: Thirty patients scheduled for RALP were randomly assigned into one of two groups. In the ITM group (n = 15), postoperative pain was managed using 300 µg intrathecal morphine with intravenous patient-controlled analgesia (IV-PCA)...
May 5, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/28462858/neuromuscular-disorders-and-chronic-ventilation
#13
REVIEW
Stamatia Alexiou, Joseph Piccione
Morbidity and mortality have decreased in patients with neuromuscular disease due to implementation of therapies to augment cough and improve ventilation. Infants with progressive neuromuscular disease will eventually develop respiratory complications as a result of muscle weakness and their inability to compensate during periods of increased respiratory loads. The finding of nocturnal hypercapnia is often the trigger for initiating non-invasive ventilation and studies have shown that its use not only may improve sleep-disordered breathing, but also that it may have an effect on daytime function, symptoms related to hypercapnia, and partial pressure of CO2...
April 24, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28403863/laparoscopic-resection-of-gastric-duplication-cysts-in-newborns-a-report-of-five-cases
#14
Hong-Xia Ren, Li-Qiong Duan, Xiao-Xia Wu, Bao-Hong Zhao, Yuan-Yuan Jin
BACKGROUND: Gastric duplication cysts are rare congenital alimentary tract anomalies and most cases are recognized during childhood. There were few reports about gastric duplication cysts in newborns and even fewer reports about laparoscopic resection of gastric duplication cysts in newborns. CASE PRESENTATION: We report a series of five newborns with gastric duplication cysts which were successfully resected by laparoscopy between January 2010 and April 2015. Case 1, a male newborn was admitted because of severe salivation, choking cough and dyspnea for 30 min after birth...
April 12, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28363626/validating-signs-and-symptoms-from-an-actual-mass-casualty-incident-to-characterize-an-irritant-gas-syndrome-agent-igsa-exposure-a-first-step-in-the-development-of-a-novel-igsa-triage-algorithm
#15
Joan M Culley, Jane Richter, Sara Donevant, Abbas Tavakoli, Jean Craig, Salvatore DiNardi
INTRODUCTION: Chemical exposures can pose a significant threat to life. Rapid assessment by first responders/emergency nurses is required to reduce death and disability. Currently, no informatics tools for irritant gas syndrome agents (IGSA) exposures exist to process victims efficiently, continuously monitor for latent signs/symptoms, or make triage recommendations. This study describes the first step in developing ED informatics tools for chemical incidents: validation of signs/symptoms that characterize an IGSA syndrome...
March 28, 2017: Journal of Emergency Nursing: JEN: Official Publication of the Emergency Department Nurses Association
https://www.readbyqxmd.com/read/28356637/rate-of-oral-intake-and-effects-of-mechanical-insufflation-exsufflation-on-pulmonary-complications-in-patients-with-duchenne-muscular-dystrophy
#16
Toshihiko Miura, Akiyoshi Takami, Misato Makino, Akira Ishikawa, Yuka Ishikawa
[Purpose] In Duchenne muscular dystrophy, it increases risks of difficulties of expectoration of secretion, asphyxia, aspiration pneumonia because of decreased cough function. The aim of this study is to prove that manually assisted coughing or mechanical insufflation-exsufflation prevents pulmonary complication and contribute to continue oral intake safely and continue rate of oral intake in Duchenne muscular dystrophy. [Subjects and Methods] We investigated the status of using ventilator, manually assisted coughing or mechanical insufflation-exsufflation, and oral intake or not...
March 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28353595/eotaxin-and-il-4-levels-are-increased-in-induced-sputum-and-correlate-with-sputum-eosinophils-in-patients-with-nonasthmatic-eosinophilic-bronchitis
#17
Rui Zhang, Wei Luo, Zhenyu Liang, Yaxia Tan, Ruchong Chen, Wenju Lu, Nanshan Zhong
Nonasthmatic eosinophilic bronchitis (NAEB) is characterized by chronic cough and airway eosinophilic inflammation. Airway and systemic inflammation cytokine profile have not been comprehensively described in patients with NAEB.The aim of the study was to identify the cytokine profile in sputum and serum of NAEB patients. Furthermore, the relationship between cytokines and clinical features would be evaluated.Induced sputum and serum were collected from untreated NAEB patients and healthy subjects. The cytokine profile in sputum and serum was analyzed by a bead-based multiplex cytokine assay including 21 cytokines...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28338488/respiratory-complications-management-and-treatments-for-neuromuscular-disease-in-children
#18
MyMy C Buu
PURPOSE OF REVIEW: To summarize current literature describing the respiratory complications of neuromuscular disease (NMD) and the effect of respiratory interventions and to explore new gene therapies for patients with NMD. RECENT FINDINGS: Measurements of respiratory function focus on vital capacity and maximal inspiratory and expiratory pressure and show decline over time. Management of respiratory complications includes lung volume recruitment, mechanical insufflation-exsufflation, chest physiotherapy and assisted ventilation...
June 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/28323731/thymic-carcinoma-with-endobronchial-metastasis-a-case-report
#19
Makoto Nagamata, Yusuke Okuma, Yukio Hosomi, Tsunekazu Hishima
Thymic carcinoma is a rare cancer, accounting for only 1% to 4% of thymic epithelial tumors. Endobronchial metastasis is a rare presentation of these tumors. A 64-year-old man presented with a cough. Lung cancer was suspected because a chest radiograph showed a 7-cm mass in the left pulmonary hilum. Computed tomography showed a mass in the anterior mediastinum and an infiltrate in the upper lobe of the left lung. Bronchoscopy demonstrated bilateral polypoid tumors in the left B bronchus and the right B bronchus...
April 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28315177/physical-symptoms-screening-for-cardiopulmonary-complications-of-obesity-using-audio-computer-assisted-self-interviews
#20
Jorge L Morales-Estrella, Farah D Ciftci, William E Trick, Keiki Hinami
PURPOSE: The main study objective was to assess the predictive value of selected physical symptoms for screening obstructive sleep apnea and major cardiac conditions in adults with obesity, thus providing the evidence for routine symptom screening of obesity complications endorsed by obesity management clinical practice guidelines. METHODS: We performed a retrospective cohort study using patient-reported outcomes data including the physical symptoms severity component of the Memorial Symptom Assessment Scale administered through Audio Computer-Assisted Self-Interviews combined with data from the electronic medical records of an urban safety-net primary care clinic...
March 17, 2017: Quality of Life Research
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