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https://www.readbyqxmd.com/read/28338469/the-utility-of-thyroid-ultrasonography-in-the-management-of-thyroid-nodules
#1
Gary Gamme, Tyler Parrington, Edward Wiebe, Sunita Ghosh, Brendan Litt, David C Williams, Todd P W McMullen
BACKGROUND: Ultrasonography for thyroid nodules is one of the most common imaging tests performed in the general population. Details from ultrasound reports guide biopsies and surgery. This study quantifies the completeness of these reports based on Thyroid Imaging and Reporting System (TI-RADS) criteria and considers their utility in predicting malignant disease. METHODS: We retrospectively reviewed ultrasound reports for 329 thyroidectomy patients and extracted data elements using the TI-RADS criteria: nodule size, echogenicity, margins, vascularity, solid/cystic composition and the presence or absence of microcalcifications and the halo sign...
April 2017: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://www.readbyqxmd.com/read/28338234/extent-of-surgery-did-not-affect-recurrence-during-7-years-follow-up-in-papillary-thyroid-cancer-sized-1-4-cm-preliminary-results
#2
Min Joo Kim, Myung-Chul Lee, Guk Haeng Lee, Hoon Sung Choi, Sun Wook Cho, Su-Jin Kim, Kyu Eun Lee, Young Joo Park, Do Joon Park
OBJECTIVE: There is debate whether hemithyroidectomy is sufficient for patients with papillary thyroid cancer (PTC) sized 1-4 cm. Therefore, we investigated whether hemithyroidectomy affects recurrence rate compared with thyroidectomy in patients with PTC sized 1-4 cm. DESIGN: Retrospective observational study. PATIENTS: We included 147 patients with 1-4 cm PTC who underwent hemithyroidectomy between 2004 and 2008. They were matched with 298 patients who underwent thyroidectomy, comparing age, sex, tumor size, multiplicity, and extrathyroidal extension status, and lymph node (LN) metastasis status...
March 24, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28337674/painful-hashimoto-s-thyroiditis-myth-or-reality
#3
REVIEW
M Rotondi, V Capelli, P Locantore, A Pontecorvi, L Chiovato
Neck pain is a common complain, being in most cases due to non-thyroidal causes. However, a minority of patients suffer from painful thyroid diseases. Among them, sub-acute thyroiditis (SAT) is the most frequent one. Rare thyroid-related causes of neck pain include hemorrhage within a thyroid nodule as well as Riedel's thyroiditis and suppurative thyroiditis. In the last 30 years, a few cases of a painful variant of Hashimoto's thyroiditis (HT) have been described. Biochemical, ultrasound, and histologic features were clearly suggestive for HT in all of the published cases and definitely ruled out the diagnosis of SAT...
March 24, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28337546/robotic-thyroidectomy-versus-conventional-open-thyroidectomy-for-thyroid-cancer-a-systematic-review-and-meta-analysis
#4
Jing-Hua Pan, Hong Zhou, Xiao-Xu Zhao, Hui Ding, Li Wei, Li Qin, Yun-Long Pan
BACKGROUND: Despite the new technical alternative offered by the robotic surgery for minimally invasive thyroid surgery, the role of the robotic thyroidectomy (RT) in thyroid cancer has been highly disputed. This paper gives a systematic review and meta-analysis aiming to compare RT and open thyroidectomy (OT) based on the surgical outcomes and oncologic results. METHODS: Relevant literature was searched from various databases up to July 2016, including PubMed, MEDLINE, EMBASE, Cochrane Library, Web of science and Clinical Trials...
March 23, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28332062/diagnosis-and-treatment-of-metastases-to-the-thyroid-gland-a-meta-analysis
#5
REVIEW
Patrizia Straccia, Claudia Mosseri, Chiara Brunelli, Esther Diana Rossi, Celestino Pio Lombardi, Alfredo Pontecorvi, Guido Fadda
The thyroid is a rare site of clinically detectable tumor metastases; even though the gland is a highly vascularized structure, the frequency of metastases in the routine practice is less than 0.2% of all thyroid malignancies. The purpose of our meta-analysis is to evaluate the frequency of metastatic diffusion from other primary tumors to the thyroid gland and to suggest the best possible treatment through an evidence-based study. Relevant studies were identified by searching the following databases: PubMed, Scopus, and Web of Science...
March 22, 2017: Endocrine Pathology
https://www.readbyqxmd.com/read/28332058/bilateral-axillo-breast-approach-robotic-thyroidectomy-baba-rt-does-not-interfere-with-breast-image-follow-up
#6
Hyeong Won Yu, Young Jun Chai, Hyungju Kwon, Su-Jin Kim, June Young Choi, Kyu Eun Lee
BACKGROUND: Bilateral axillo-breast approach robotic thyroidectomy (BABA RT) is frequently performed and has excellent cosmetic results. However, there has been concern that subcutaneous tunneling in construction of the operation field might interfere with subsequent breast imaging. In this study, we evaluated whether BABA RT interferes with breast imaging by evaluating serial perioperative results of mammography and ultrasonography. METHODS: We selected female patients who underwent BABA RT between 2008 and 2012, and who also had mammography or ultrasonography pre- and postoperatively, and compared the results of pre- and postoperative imaging...
March 22, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28330547/-ectopic-thyroid-tissue-with-a-primary-carcinoma
#7
Pernille Hammershøj Jensen, Anette Pedersen Pilt, Hans-Erik Wittendorff
Ectopic thyroid tissue is a result of abnormal embryologic development and migration of the thyroid gland. It has a prevalence of one per 100,000-300,000, and the risk of malignant transformation in ectopic thyroid tissue is rare. We present a rare case of perivesical ectopic papillary thyroid carcinoma in a 76-year-old man with a normal orthotopic thyroid gland. A total thyroidectomy was performed, and the pathology report showed normal thyroid tissue with no neoplastic involvement. The patient was treated with radioactive iodine, and a control scintigraphy was without any signs of activity...
March 20, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28329426/clinicopathological-characteristics-including-braf-v600e-mutation-status-and-pet-ct-findings-in-papillary-thyroid-carcinoma
#8
Eun Kyoung Choi, Ari Chong, Jung-Min Ha, Chan Kwon Jung, Joo Hyun O, Sung Hoon Kim
OBJECTIVE: We assessed the associations between FDG uptake in primary papillary thyroid carcinomas (PTCs) and clinicopathological features, including the BRAF V600E mutation, using quantitative and qualitative analyses of preoperative PET/CT data. DESIGN AND PATIENTS: This was a retrospective review of 106 patients with PTC who underwent PET/CT scans between February 2009 and January 2011 before undergoing total thyroidectomy. Data collected from surgical specimens were compared with FDG uptake in the primary tumor using quantitative and qualitative analyses of preoperative PET/CT data...
March 22, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28327204/lung-adenocarcinoma-with-thyroid-metastasis-a-case-report
#9
A Dao, H Jabir, A Taleb, N Benchakroun, Z Bouchbika, T Nezha, H Jouhadi, S Sahraoui, A Benider
BACKGROUND: The metastases of a primary lung cancer over the thyroid gland are extremely rare. We report on an unusual presentation of thyroid metastasis of lung cancer in order to improve the management of similar cases. CASE PRESENTATION: Three years ago, a Moroccan male 59-year-old was admitted for dyspnea, dry cough, and chest pain. He had smoked about 30 cigarette packs a year. Clinical examination revealed a right thyroid nodule. Chest and neck computed tomography (CT) scan showed a proximal left tumor in contact with the pulmonary artery and revealed a suspected nodule in the right lobe of the thyroid with homolateral neck node...
March 21, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28326742/comparative-assessment-of-calcitonin-stimulation-test-using-calcium-gluconate-and-pentagastrin-and-the-usefulness-of-procalcitonin-basic-and-post-stimulation-concentrations-in-the-diagnosis-of-patients-after-surgery-for-medullary-thyroid-cancer
#10
(no author information available yet)
OBJECTIVES: The aim of the study was to compare the calcitonin (CT) stimulation tests with tests of calcium gluconate (CaG) and pentagastrin (PG), their tolerance and usefulness of PCT in the patients' diagnosis with active Medullary thyroid cancer (MCT) after thyroidectomy. METHODS: CT was marked in serum by the immunosorbent sandwich test. PCT was marked by the immunosorbent sandwich test, with the final reading of fluorenscence. PG was given intravenously at a dose of 0...
December 22, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28325735/rescue-preoperative-treatment-with-lugol-s-solution-in-uncontrolled-graves-disease
#11
Jan Calissendorff, Henrik Falhammar
BACKGROUND: Graves' disease is a common cause of hyperthyroidism. Three therapies have been used for decades: pharmacologic therapy, surgery and radioiodine. In case of adverse events, especially agranulocytosis or hepatotoxicity, pre-treatment with Lugol's solution containing iodine/potassium-iodide to induce euthyroidism before surgery could be advocated but has rarely been reported. METHOD: All patients hospitalised due to uncontrolled hyperthyroidism at the Karolinska University Hospital 2005-2015 and treated with Lugol's solution were included...
March 21, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28325623/impact-of-body-mass-index-on-survival-outcome-in-patients-with-differentiated-thyroid-cancer
#12
Yousif Al-Ammar, Bader Al-Mansour, Omar Al-Rashood, Mutahir A Tunio, Tahera Islam, Mushabbab Al-Asiri, Khalid Hussain Al-Qahtani
INTRODUCTION: Increased body mass index (BMI) is known to be associated with the high prevalence of Differentiated Thyroid Cancers (DTC); however data on its impact on survival outcome after thyroidectomy and adjuvant therapy is scanty. OBJECTIVE: We aimed to evaluate the impact of BMI on overall survival (OS) and disease free survival (DFS) rates in patients with DTC. METHODS: Between 2000 and 2011, 209 patients with DTC (papillary, follicular, hurthle cell) were treated with thyroidectomy followed by adjuvant radioactive iodine-131 (RAI) therapy and thyroid-stimulating hormone (TSH) suppression...
February 28, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28323992/quantification-of-thyroid-cancer-and-multinodular-goiter-risk-in-the-dicer1-syndrome-a-family-based-cohort-study
#13
Nicholas E Khan, Andrew J Bauer, Kris Ann P Schultz, Leslie Doros, Rosamma M Decastro, Alexander Ling, Maya B Lodish, Laura A Harney, Ron G Kase, Ann G Carr, Christopher T Rossi, Amanda Field, Anne K Harris, Gretchen M Williams, Louis P Dehner, Yoav H Messinger, D Ashley Hill, Douglas R Stewart
Context: The risk of thyroid cancer and multinodular goiter (MNG) in the DICER1 syndrome, a rare tumor-predisposition disorder, is unknown. Objective: To quantify the risk of thyroid cancer and MNG in individuals with the DICER1 syndrome. Design: Family-based cohort study. Setting: National Institutes of Health (NIH) Clinical Center (CC). Participants: The National Cancer Institute DICER1 syndrome cohort consisted of 145 individuals with a DICER1 germline mutation and 135 family controls from 48 families...
February 2, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28323957/risk-profile-of-the-ret-a883f-germline-mutation-an-international-collaborative-study
#14
Jes Sloth Mathiesen, Mouhammed Amir Habra, John Howard Duncan Bassett, Sirazum Mubin Choudhury, Sabapathy Prakash Balasubramanian, Trevor A Howlett, Bruce G Robinson, Anne-Paule Gimenez-Roqueplo, Frederic Castinetti, Peter Vestergaard, Karin Frank-Raue
Context: The A883F germline mutation of the REarranged during Transfection proto-oncogene causes multiple endocrine neoplasia 2B. In the revised American Thyroid Association (ATA) guidelines for the management of medullary thyroid carcinoma (MTC) the A883F mutation has been reclassified from the highest to high risk level, although no well-defined risk profile for this mutation exists. Objective: To create a risk profile for the A883F mutation for appropriate classification in the ATA risk levels...
March 17, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28322121/thyroglossal-duct-cyst-carcinoma-a-systematic-review-of-clinical-features-and-outcomes
#15
Hani M Rayess, Ian Monk, Peter F Svider, Amar Gupta, S Naweed Raza, Ho-Sheng Lin
Objective Although thyroglossal duct cysts (TGDCs) are relatively common, malignancies within these lesions are infrequent. As a result, there are no large-scale series describing clinical characteristics. Our objectives were to perform a systematic review of the literature evaluating patient demographics, pathology, management, and prognosis of these patients. Data Sources PubMed, Embase, Cochrane reviews, and Google Scholar were searched for relevant articles. Articles meeting inclusion criteria were reviewed for data detailing epidemiology, treatment, and outcomes...
March 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28316221/-value-of-jugulo-omohyoid-lymph-nodes-in-predicting-lateral-cervical-occult-metastasis-in-patients-with-papillary-thyroid-carcinoma
#16
C M An, Y Wang, S X Wang, Y L Yin, M Q Chen, Z G Xu, P Z Tang, Z J Li
Objective: To investigate the value of jugulo-omohyoid lymph nodes (JOHLN) in predicting occult lateral cervical lymph node metastasis in patients with papillary thyroid carcinoma (PTC). Methods: The clinicopathological data of 136 out of 2 100 PTC patients, who had a high risk of lateral neck lymph node metastasis and treated by us from January 2010 to December 2015, were retrospectively analyzed. Super selective neck dissection (SSND, level Ⅲ and Ⅳ)was performed and JOHLNs were sent for frozen section in all the 136 cases...
March 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28315910/effect-of-selenium-supplementation-for-protection-of-salivary-glands-from-iodine-131-radiation-damage-in-patients-with-differentiated-thyroid-cancer
#17
Haiyoung Son, Sang Mi Lee, Ra Gyoung Yoon, Hakmin Lee, Ilkyun Lee, Soon Kim, Woong Youn Chung, Jeong Won Lee
OBJECTIVE: In the current study, we examined whether selenium supplementation during iodine-131 ((131)I) treatment had a radio-protective effect on salivary glands. SUBJECTS AND METHODS: Sixteen patients with differentiated thyroid cancer were prospectively enrolled in the study. Patients after total thyroidectomy, before (131)I treatment, were divided into two groups; 8 patients in the selenium group and 8 patients in the control group. Patients in the selenium group received 300νg of selenium orally for 10 days, from 3 days before to 6 days after (131)I treatment...
March 20, 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28304123/incidental-parathyroidectomy-during-total-thyroidectomy-is-not-a-direct-cause-of-post-operative-hypocalcaemia
#18
Carolyn Chew, Ran Li, Michael K Ng, Steven T F Chan, Bill Fleming
BACKGROUND: Post-operative hypocalcaemia is the most common complication after total thyroidectomy, with a reported incidence of transient hypocalcaemia up to 50% and permanent hypocalcaemia 1.5-4%. The impact of incidental parathyroidectomy (IPE) on post-operative hypocalcaemia remains controversial. This study evaluated the risk factors for IPE following total thyroidectomy and compared post-operative calcium levels serially between patients with and without IPE. METHODS: A retrospective analysis of patients undergoing total thyroidectomy from January 2009 to October 2016 at Western Health was conducted...
March 17, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28302227/anaesthetic-concerns-of-surgical-emphysema-following-thyroidectomy
#19
Sanum Kashif, Amna Gulrez
Surgical emphysema secondary to tracheal tear is a rare but serious complication after thyroidectomy. It is usually resolved by conservative management; but in case of compromised airway, early airway control and surgical intervention is required. This is the case report of a 52-year woman diagnosed as thyroid carcinoma, who developed rapidly progressive surgical emphysema involving head and upper thorax, following total thyroidectomy, in post anesthesia care unit (PACU). The complication was related to tracheal tear occurring during excision of huge thyroid mass, encroaching trachea...
March 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28302162/total-thyroidectomy-may-be-more-reasonable-as-initial-surgery-in-unilateral-multifocal-papillary-thyroid-microcarcinoma-a-single-center-experience
#20
Shuai Xue, Peisong Wang, Jia Liu, Guang Chen
BACKGROUND: The extent of surgery in patients with unilateral multifocal papillary thyroid microcarcinoma (UMPTMC) remains to be controversial. Aimed to improve surgical management of UMPTMC, this study was performed to identify the recurrence of UMPTMC and analyze its predictive factors. METHODS: This study was approved by the Ethical Committee of The First Hospital of the Jilin University, and written informed consent was given by participants for their clinical records to be used in this study...
March 16, 2017: World Journal of Surgical Oncology
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