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https://www.readbyqxmd.com/read/28231691/evaluation-of-diagnostic-performance-of-screening-thyroid-ultrasonography-us-and-imaging-findings-of-screening-detected-thyroid-cancer
#1
Jeongin Yoo, Hye Shin Ahn, Soo Jin Kim, Sung Hee Park, Mirinae Seo, Semin Chong
Purpose: To evaluate the diagnostic performance and cost of screening thyroid ultrasonography (US) in an asymptomatic population and determine the US features of screening-detected thyroid cancer. Materials and Methods: This study included 1845 asymptomatic participants who underwent screening thyroid US between March and August 2012 at the screening center in our hospital. We evaluated the diagnostic performance of screening thyroid US for thyroid cancer and the average cost of diagnosis for each patient...
February 24, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28229842/-thyroid-metastasis-as-the-initial-presentation-of-an-asymptomatic-clear-cell-renal-carcinoma
#2
Janine Carmelino, Ana Paula Tavares, Ana Crespo, José Mário Coutinho, António Lázaro, Vasco Ribeiro, Eduardo Barroso
INTRODUCTION: Clear cell renal carcinoma metastases to the thyroid gland are rare and only diagnosable after an immunohistochemistry analysis of the histological sample. The purpose of this article is to report a case of thyroid metastasis as the initial presentation of a clear cell renal carcinoma. CASE REPORT: Male patient with a solid nodule in the left lobe of the thyroid, 5.3 cm in diameter, suspicious of malignancy, for which a total thyroidectomy with central compartment lymphadenectomy was performed...
November 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28226001/recombinant-human-tsh-versus-thyroid-hormone-withdrawal-in-adjuvant-therapy-with-radioactive-iodine-of-patients-with-papillary-thyroid-carcinoma-and-clinically-apparent-lymph-node-metastases-not-limited-to-the-central-compartment-cn1b
#3
Pedro Weslley Rosario, Gabriela Franco Mourão, Maria Regina Calsolari
Objective: To compare the short- and long-term outcomes of adjuvant therapy with radioactive iodine (RAI) preceded by the administration of recombinant human TSH (rhTSH) versus thyroid hormone withdrawal (THW) in patients with papillary thyroid carcinoma and clinically apparent lymph node metastases not limited to the central neck compartment (cN1b). Subjects and methods: The sample consisted of 178 cN1b patients at intermediate risk who underwent total thyroidectomy with apparently complete tumor resection [including postoperative ultrasonography (US) without anomalies] and who received adjuvant therapy with RAI (30-100 mCi) preceded by the administration of rhTSH (n = 91) or THW (n = 87)...
February 13, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28225857/malignant-melanoma-with-synchronous-thyroid-metastases-case-report-and-literature-review
#4
Maria Manuel Costa, Sandra Belo, João Capela-Costa, Jennifer Costa, Davide Carvalho
Thyroid metastases are rare in clinical practice. We describe the case of an 85-year-old woman who was referred to our department due to a multinodular goiter with compressive symptoms and subclinical hyperthyroidism. The patient was also undergoing evaluation for a polyp in her left nasal cavity, which was then diagnosed as a malignant melanoma of the nasal mucosa. A thoracoabdominal magnetic resonance imaging obtained for cancer staging revealed a > 50% tracheal obstruction caused by the goiter. The patient underwent simultaneous total thyroidectomy and melanoma excision...
February 16, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28224278/the-need-of-prophylactic-central-lymph-node-dissection-is-controversial-in-terms-of-postoperative-thyroglobulin-follow-up-of-patients-with-cn0-papillary-thyroid-cancer
#5
Mehmet Hakan Korkmaz, Bülent Öcal, Güleser Saylam, Erman Çakal, Ömer Bayır, Esra Tutal, Emel Çadallı Tatar
PURPOSE: The objective of this study was to investigate whether prophylactic central lymph node dissection (pCLND) facilitates postoperative thyroglobulin (Tg) follow-up in the patients with papillary thyroid carcinoma (PTC). We also questioned whether radioactive iodine (RAI) remnant ablation provides any further advantage in this regard. METHODS: The records of patients with low-intermediate risk PTC who underwent either only total thyroidectomy (TT) or TT in conjunction with pCLND were reviewed...
February 21, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/28223546/skip-lateral-lymph-node-metastasis-leaping-over-the-central-neck-compartment-in-papillary-thyroid-carcinoma
#6
Jianyong Lei, Jinjing Zhong, Ke Jiang, Zhihui Li, Rixiang Gong, Jingqiang Zhu
OBJECTIVE: This study was performed to investigate the frequency and pattern as well as the predictive factors of skip metastasis (lateral cervical lymph node metastasis without central lymph node metastasis) in papillary thyroid carcinoma (PTC). METHODS: 450 PTC patients who received total thyroidectomy with central neck dissection(CND) combined with modified radical lateral neck dissection(LND) were divided into two groups: with or without skip metastases. The clinicopathological characteristics were statistically compared and analyzed, and univariate and multivariate analyses were performed to detect the risk factors of skip metastasis...
February 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28223197/bethesda-category-iii-iv-and-v-thyroid-nodules-can-nodule-size-help-predict-malignancy
#7
Colleen M Kiernan, Carmen C Solórzano
BACKGROUND: The association of tumor size with malignancy in thyroid nodules with indeterminate cytology: atypia/follicular lesion of undetermined significance (AUS/FLUS), suspicious for follicular (SFN)/Hürthle cell neoplasm (HCN), and suspicious for malignancy(SM) has not been clearly studied. STUDY DESIGN: We retrospectively identified 1,104, patients who underwent thyroid FNA and subsequent thyroidectomy. Patients with indeterminate cytology were reviewed. The size of the nodule was determined by ultrasound...
February 18, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28222967/clinical-implications-of-microscopic-extrathyroidal-extension-in-patients-with-papillary-thyroid-carcinoma
#8
Ji Su Park, Jae Won Chang, Lihua Liu, Seung-Nam Jung, Bon Seok Koo
BACKGROUND: Extrathyroidal extension (ETE) is a poor prognostic factor in papillary thyroid carcinoma (PTC). However, the impact of the degree of ETE, especially microscopic ETE, has not been well established. The purpose of present study was to compare differences in clinicopathological characteristics and clinical outcomes according to the presence or extent of ETE. METHODS: Data from 381 patients who underwent total thyroidectomy with/without lymph node (LN) dissection for PTC between 2004 and 2010 were analyzed...
February 17, 2017: Oral Oncology
https://www.readbyqxmd.com/read/28222412/low-risk-papillary-thyroid-carcinoma-patients-who-underwent-near-total-thyroidectomy-without-prophylactic-central-compartment-lymph-node-dissection-and-were-ablated-with-low-dose-50mci-rai-had-excellent-10-year-prognosis
#9
Marina Michalaki, Panagiotis Bountouris, Nikolaos D Roupas, Anastasia Theodoropoulou, Niki Agalianou, Theodoros Alexandrides, Kostas Markou
BACKGROUND: The current trend in the management of low risk differentiated thyroid carcinoma is to follow less aggressive strategies. OBJECTIVE: To assess the long-term morbidity and mortality outcomes of low-risk papillary thyroid carcinoma (PTC) patients undergoing minimal intervention. DESIGN: We retrospectively analyzed 137 patients with low-risk PTC (stage I: n=77; stage II: n=60). Of these patients, 107 (Group 1) had macro-PTC and underwent near-total thyroidectomy and received postoperatively 50mCi RAI...
October 2016: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28217964/is-fine-needle-aspiration-really-not-necessary-in-patients-with-thyroid-nodules%C3%A2-%C3%A2-%C3%A2-1-cm-with-highly-suspicious-features-on-ultrasonography-and-candidates-for-active-surveillance
#10
Pedro Weslley Rosario, Alexandre Lemos Silva, Maria Regina Calsolari
BACKGROUND: The low rate of progression associated with the potential complications of thyroidectomy makes active surveillance an increasingly recommended management in low-risk papillary microcarcinomas of the thyroid (PMT). The objective of this study was to report the results of fine needle aspiration (FNA) of nodules ≤ 1 cm with highly suspicious appearance on ultrasonography (US) in patients who are potential candidates for active surveillance. METHODS: We revised thyroid nodules ≤ 1 cm with highly suspicious appearance on US in patients without known distant metastases, suspicion of extrathyroid extension, or suspicious lymph nodes on US...
February 20, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28217498/usefulness-of-pre-and-post-operative-calcium-and-vitamin-d-supplementation-in-prevention-of-hypocalcemia-after-total-thyroidectomy-a-randomized-controlled-trial
#11
Sumiya Jaan, Ashish Sehgal, Rauf Ahmad Wani, Muneer Ahmad Wani, Khursheed Alam Wani, Bashir Ahmad Laway
BACKGROUND: Total thyroidectomy (TT) is a commonly performed surgery and postoperative hypocalcemia is a major detriment to early discharge. The aim of this randomized controlled trial was to ascertain the usefulness of routine pre- and post-operative calcium and Vitamin D supplementation in prevention of hypocalcemia after TT. MATERIALS AND METHODS: Sixty consecutive patients who underwent total or near TT from February 2013 to August 2014 were included in the study...
January 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28217014/antithyroglobulin-antibody-as-a-marker-of-successful-ablation-therapy-in-differentiated-thyroid-cancer
#12
Ayu Rosemeilia Dewi, Budi Darmawan, Achmad Hussein Sundawa Kartamihadja, Basuki Hidayat, Johan S Masjhur
The aim of this study was to determine the role of antithyroglobulin antibody (ATA) serum as a marker of successful I-131 ablation therapy in differentiated thyroid cancer (DTC) patients with low serum thyroglobulin (Tg). A retrospective study was conducted on 60 patients (10 males and 50 females). All patients underwent posttotal thyroidectomy and received 2.96 to 3 GBq I-131 ablation. Subjects were divided into two groups with succesful and unsuccessful I-131 ablation therapies. The data of age, gender, histopathologic type, tumor size, and metastasis were collected...
January 2017: World Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28214213/the-relationship-between-brafv600e-nf-%C3%AE%C2%BAb-and-tgab-expression-in-papillary-thyroid-carcinoma
#13
Wei Li, Hui Ming, Danyang Sun, Wei Li, Dan Wang, Guizhi Zhang, Jian Tan
PURPOSE: The aim of this study was to investigate the potential link between thyroglobulin antibody (TgAb) titers and papillary thyroid carcinoma (PTC) aggressiveness. MATERIALS AND METHODS: This retrospective study included 122 patients who had undergone total thyroidectomy and neck central area lymph dissection followed by radioactive iodine (RAI) ablation for PTC between July 2012 and July 2014. The parameters included clinical characteristics of PTC, TgAb levels and tumor histopathological characteristics...
January 12, 2017: Pathology, Research and Practice
https://www.readbyqxmd.com/read/28212628/is-propofol-injection-pain-really-important-to-patients
#14
Wen Wang, Linxin Wu, Chaobin Zhang, Li Sun
BACKGROUND: Propofol injection pain (PIP) has been adequately studied during the past decades. However, patients' opinion on this problem and the incidence of patients' recall of this brief discomfort are still unknown. Thus, we conducted this study to know the patients' perspectives on PIP and provide useful information about the incidence of recall of PIP under our routine general anesthesia. METHODS: Five hundred preoperative questionnaires were distributed to patients who were scheduled for elective open thyroidectomy under general anesthesia from May 2016 to July 2016...
February 17, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28208891/outcomes-of-capsular-dissection-technique-with-use-of-bipolar-electrocautery-in-total-thyroidectomy-a-rural-tertiary-center-experience
#15
Amal T Das, S B Prakash, V Priyadarshini
INTRODUCTION: Total thyroidectomy is one of the most routinely performed head and neck surgical procedures with extremely low mortality. This procedure has been associated with two major complications such as recurrent laryngeal nerve injury and hypocalcaemia due to parathyroid insufficiency. The use of bipolar electrocautery has not been widely accepted in view of thermal damage to adjacent structures. AIM: To study the outcomes and complications of capsular dissection technique along with use of bipolar electrocautery in total thyroidectomy...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28207532/synchronous-papillary-thyroid-carcinoma-and-breast-ductal-carcinoma-a-rare-case-report-and-literature-review
#16
Jinjing Zhong, Jianyong Lei, Ke Jiang, Zhihui Li, Rixiang Gong, Jingqiang Zhu
BACKGROUND: The incidences of both thyroid cancer and breast cancer have been rising in recent years; however, it is very rare to find a single person with both of these cancers. Only a few cases of synchronous thyroid and breast cancer have been published, and even fewer cases have been reported in older patients (>60 years). CASE SUMMARY: The current study presents a case of synchronous papillary thyroid carcinoma and breast ductal carcinoma in an elderly patient...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28207517/a-rare-case-report-of-very-low-thyroglobulin-and-a-negative-whole-body-scan-in-a-patient-with-a-solid-variant-of-papillary-thyroid-carcinoma-with-distant-metastases
#17
Wei Li, Danyang Sun, Hui Ming, Guizhi Zhang, Jian Tan
RATIONALE: The early detection of recurrent differentiated thyroid carcinoma (DTC) cells in postsurgery DTC patients relies on the sensitivity of measuring both the level of thyroglobulin (Tg) and 131-iodine distribution on a whole-body scan (WBS). Recent studies have defined patients who subsequently have no evidence of disease as those who have a stimulated Tg level <1 ng/mL with no other radiological or clinical evidence of disease. PATIENT CONCERNS: A woman patient with solid variant papillary thyroid carcinoma (SVPTC) had undergone twice thyroidectomy with lymph node dissection and radioactive therapy...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28204971/the-presence-of-cancerous-nodules-in-lymph-nodes-is-a-novel-indicator-of-distant-metastasis-and-poor-survival-in-patients-with-papillary-thyroid-carcinoma
#18
Ling Chen, Youzhi Zhu, Ke Zheng, Huihao Zhang, Hongkun Guo, Li Zhang, Kunlin Wu, Lingjun Kong, Weihong Ruan, Jianying Hu, Xin Zhang, Xiangjin Chen
PURPOSE: Several characteristics of lymph node metastasis (LNM) as predictors of the risk of recurrence or death were examined in patients with papillary thyroid carcinoma (PTC). The presence of cancerous nodules as a characteristic of LNMs in PTC has not yet been reported. The objective of this study was to evaluate the use of the cancerous nodules in the lymph node (CNLN) to determine the risk of distant metastasis and survival in patients with PTC. METHODS: This retrospective observational cohort study enrolled 1408 patients with pathologically confirmed PTC without initial distant metastasis who underwent thyroidectomy and neck dissection...
February 15, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28203373/a-silent-skull-metastatic-follicular-thyroid-carcinoma-mimicking-as-a-benign-scalp-tumor-in-a-pregnant-woman
#19
Tsung-Chun Huang, Yu-Kai Cheng, Tsung-Wei Chen, Yung-Chang Hsu, En-Wei Liu, Hsin-Han Chen
: Thyroid cancer with cranial metastasis in a pregnant woman is very rare. In the literature, most cases are diagnosed early from neurogenic signs or symptomatic thyroid gland. Pregnancy also contributes to a hesitation toward early surgical and medical treatments. We reported a scalp tumor in a physically healthy 37-year-old pregnant female with a follicular thyroid carcinoma (FTC) with lung, bone and cranial metastasis in initial presentation. Silent neurogenic and physical examinations make an early diagnosis very challenging...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/28194664/phrenic-nerve-stimulation-during-neck-dissection-for-advanced-thyroid-cancer-involving-level-iv-is-it-worth-doing-it
#20
Carlos S Duque, Juan P Dueñas, Marcela Marulanda, Diana Pérez, Andres Londoňo, Soham Roy, Mai Al Khadem
During thyroidectomy and neck dissection surgery for advanced or recurrent metastatic thyroid cancer under intraoperative monitoring, we used the available technology to assess the feasibility of such an intervention to monitor those patients with phrenic nerves at risk. A retrospective review of patients operated on from January 2009 to December 2015 by a single surgeon (CSD) was conducted. Patients who had neck and mediastinal dissection, with or without total thyroidectomy, due to advanced or recurrent metastatic disease to the neck were selected...
February 13, 2017: Updates in Surgery
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