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https://www.readbyqxmd.com/read/28742537/update-in-natural-orifice-translumenal-endoscopic-surgery-notes
#1
Joern Bernhardt, Sarah Sasse, Kaja Ludwig, Peter N Meier
PURPOSE OF REVIEW: The recent developments and clinical applications of natural orifice translumenal endoscopic surgery (NOTES)-procedures and technologies are going to be presented. RECENT FINDINGS: In experimental as well as clinical settings, NOTES-procedures are predominantly performed in hybrid technique. Current experimental studies focus on the implementation of new surgical approaches as well as on the training of procedures. One emphasis in the clinical application is transrectal and transanal interventions...
July 22, 2017: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/28741452/young-age-and-male-sex-can-predict-for-a-large-volume-central-neck-lymph-node-metastasis-in-clinical-n0-papillary-thyroid-microcarcinoma
#2
Hye-Seon Oh, Suyeon Park, Mijin Kim, Hyemi Kwon, Eyun Song, Tae-Yon Sung, Yu-Mi Lee, Won Gu Kim, Tae Yong Kim, YoungKee Shong, Won Bae Kim, MinJi Jeon
<b><i>Background</i></b> Large-volume lymph node metastasis (LNM) is associated with poor clinical outcomes in papillary thyroid microcarcinoma (PTMC) patients. However, sensitivity in the detection of central neck LNM on preoperative neck ultrasonography (US) is believed to be low. The aim of this study is to investigate the preoperative clinical factors associated with large volume LNM in clinical N0 PTMC patients. <b><i>Methods</i></b> In all, 2329 clinical N0 PTMC patients who underwent total thyroidectomy with prophylactic central lymph node (LN) dissection were evaluated...
July 25, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28741442/a-systematic-review-of-the-methods-of-diagnostic-accuracy-studies-of-the-afirma%C3%A2-gene-expression-classifier
#3
Quan-Yang Duh, Naifa Busaidy, Catherine Rahilly-Tierney, Hossein Gharib, Gregory W Randolph
BACKGROUND: The Afirma® Gene Expression Classifier (GEC) risk-stratifies Bethesda System for the Reporting of Thyroid Cytopathology class III/IV (indeterminate) thyroid nodules (ITNs) as Suspicious for malignancy or Benign. Several authors have published studies describing the diagnostic accuracy of the GEC. However, the quality of these methods has not been rigorously examined. SUMMARY: We searched Medline and EMBASE for studies published between January 1, 2010 and June 30, 2016 examining the sensitivity, specificity, negative predictive value (NPV), and positive predictive value (PPV) of the GEC...
July 25, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28741201/cost-effectiveness-of-a-locally-organized-surgical-outreach-mission-making-a-case-for-strengthening-local-non-governmental-organizations
#4
Adam Gyedu, Cameron Gaskill, Godfred Boakye, Francis Abantanga
INTRODUCTION: Many low- and middle-income countries (LMICs) have a high prevalence of unmet surgical need. Provision of operations through surgical outreach missions, mostly led by foreign organizations, offers a way to address the problem. We sought to assess the cost-effectiveness of surgical outreach missions provided by a wholly local organization in Ghana to highlight the role local groups might play in reducing the unmet surgical need of their communities. METHODS: We calculated the disability-adjusted life years (DALY) averted by surgical outreach mission activities of ApriDec Medical Outreach Group (AMOG), a Ghanaian non-governmental organization...
July 24, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28740961/isolated-thyroid-metastasis-from-renal-cell-carcinoma
#5
Ali Solmaz, Ali Muhammedoğlu, Serdar Altınay, Candaş Erçetin, Erkan Yavuz, Osman Bilgin Gülçiçek, Şenay Yalçın, Yeşim Erbil
Metastatic neoplasms of the thyroid are uncommon when compared to primary tumors of the gland. Renal cell carcinoma (RCC) is a highly aggressive tumor of the urinary system. It can spread all over the body. Isolated solitary metastases of RCC to the thyroid are very rarely observed. A 64-year-old woman with a history of left radical nephrectomy for RCC, was referred to our clinic with palpable thyroid nodule. Ultrasound confirmed the nodule on the left lobe. Histopathological examination of the thyroidectomy specimen revealed that there were two solitary metastasis of RCC...
2017: Turk J Surg
https://www.readbyqxmd.com/read/28740951/a-complication-of-thyroidectomy-do-not-forget-suture-reaction
#6
Burhan Hakan Kanat, Mehmet Buğra Bozan, Seyfi Emir, Fatih Mehmet Yazar, Fatih Erol, Özkan Alataş, Hasan Baki Altınsoy, Ali Aksu
OBJECTIVE: In this study, we aimed to present patients who have developed suture reaction and were treated in our clinic following thyroidectomy operation. MATERIAL AND METHODS: Patients who had been treated for suture reaction following thyroidectomy between January 2012 and December 2014 were retrospectively evaluated. The patients were analyzed in terms of their age, gender, duration of the symptoms, type of previous operation and treatment modality. RESULTS: Between January 2012 and December 2014, 559 thyroid/parathyroid operations were performed in our clinic...
2017: Turk J Surg
https://www.readbyqxmd.com/read/28739190/the-treatment-and-outcome-analysis-of-primary-squamous-cell-carcinoma-of-the-thyroid
#7
Ryuji Yasumatsu, Masanobu Sato, Ryutaro Uchi, Takafumi Nakano, Kazuki Hashimoto, Ryunosuke Kogo, Masahiko Taura, Mioko Matsuo, Torahiko Nakashima, Takashi Nakagawa
OBJECTIVES: Primary squamous cell carcinoma (SCC) of the thyroid is a rare disease. It usually presents with locally advanced disease and has an overall poor prognosis. In this study, we investigated the characteristics and outcomes of patients with SCC of the thyroid, and reported our experience with chemotherapy with lenvatinib in the treatment of SCC of the thyroid. METHODS: The management outcome of 10 patients who had SCC of the thyroid between January 2000 and 2015 at Kyushu University Hospital or associated facilities was reviewed...
July 21, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28738947/outpatient-total-thyroidectomy-is-safe-for-moderate-volume-surgeons
#8
Jonathan Black, Travis Cotton, Jen Jen Yeh
Traditionally, total thyroidectomy (TT) was an inpatient procedure, but recent trends indicate that patients are often discharged on the day of surgery. This has been proven safe for high-volume surgeons but has not been studied for low (<10 TT per year) and moderate volume surgeons (<24 TT per year). Retrospective review was performed for 414 total thyroidectomies between 2005 and 2013. Emergency department visits and readmissions within 30 days of surgery were captured, but were considered the same for the purpose of this analysis...
July 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28738945/disparities-in-the-care-of-differentiated-thyroid-cancer-in-the-united-states-exploring-the-national-cancer-database
#9
Kathryn Jaap, Rebekah Campbell, James Dove, Marcus Fluck, Marie Hunsinger, Jeffrey Wild, Tania Arora, Mohsen Shabahang, Joseph Blansfield
Differentiated thyroid cancer (DTC) treatment is multifaceted, and may be influenced by socioeconomic factors. The goal of this study is to examine disparities in DTC treatment. DTC patients from 1998 to 2012 were identified using the National Cancer Database. DTC was identified in 262,041 patients. The mean age was 48.2. The majority of patients (52%) received care at Comprehensive Community Cancer Programs (CCCPs). Total thyroidectomy was less common at Community Cancer Programs (CCPs) [odds ratio (OR): 0...
July 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28734186/bilateral-vocal-cord-palsy-after-total-thyroidectomy-a-new-treatment-case-reports
#10
Fong-Fu Chou, Cheng-Ming Hsu, Chi-Chih Lai, Yi-Chia Chan, Shun-Yu Chi
INTRODUCTION: Dyspnea due to bilateral vocal cord palsy after total thyroidectomy (BVCPATT) is a life-threatening complication; nevertheless, we try to avoid tracheotomy. METHODS: Using normalized glottal area (NGA), we retrospectively studied 14 patients with BVCPATT. Nine patients without dyspnea were treated conservatively, while five with dyspnea received immediate bilevel positive air-way pressure (BiPAP) treatment. Both right and left recurrent nerves were grossly intact during surgery...
June 30, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28733644/differentiating-malignant-from-benign-thyroid-nodules-with-indeterminate-cytology-by-99m-tc-mibi-scan-a-new-quantitative-method-for-improving-diagnostic-accuracy
#11
A Campennì, M Siracusa, R M Ruggeri, R Laudicella, S A Pignata, S Baldari, L Giovanella
Quantitative (99m)Tc-MIBI thyroid scintigraphy is a useful tool in differentiating malignant from benign thyroid nodules with indeterminate cytology. The aim of our report is to compare the diagnostic performance of different quantitative methods. We prospectively evaluated 20 patients affected by a thyroid nodule with a cytological diagnosis of class III or IV according to the Bethesda system. Planar images of the thyroid were acquired 10 and 60 minutes after (99m)Tc-MIBI administration and two different quantitative methods applied (i...
July 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28729773/is-new-american-thyroid-association-risk-classification-for-hereditary-medullary-thyroid-carcinoma-applicable-to-chinese-patients-a-single-center-study
#12
Xiwei Zhang, Dangui Yan, Junyi Wang, Hanfeng Wan, Yongxia Zhang, Yabing Zhang, Yuqin He, Wensheng Liu, Bin Zhang
OBJECTIVE: The American Thyroid Association (ATA) proposed a new risk classification for hereditary medullary thyroid carcinoma (MTC) in 2015. This study aimed to assess whether the new guidelines are suitable for the Chinese population, and reported our experience on prophylactic thyroidectomy. METHODS: A total of 73 patients from 22 families were screened as rearranged during transfection (RET) mutation carriers from 2010 to 2016 in Cancer Hospital, Chinese Academy of Medical Science; the medical history for each patient was collected...
June 2017: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
https://www.readbyqxmd.com/read/28729523/malignancy-rates-of-thyroid-cytology-cyst-fluid-benign-or-non-diagnostic
#13
Güven Güney, İbrahim Tayfun Şahiner
BACKGROUND We sought to investigate subgroup distribution using Bethesda classification and risks for malignancy. We also compared the malignancy risk of cases that were denoted as non-diagnostic due to cystic contents, with cases that were denoted as non-diagnostic due to presence of other features. MATERIAL AND METHODS The study included pathology test results of 1,440 thyroid nodule samples diagnosed using Bethesda classification. Results of 305 thyroidectomy excision specimens from these patients were also compared with cytology results to determine the frequency of malignancy...
July 21, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28728986/intra-capsular-total-thyroid-enucleation-versus-total-thyroidectomy-in-treatment-of-benign-multinodular-goiter-a-prospective-randomized-controlled-clinical-trial
#14
Alaa M Sewefy, Tohamy A Tohamy, Tarek M Esmael, Ahmed M Atyia
BACKGROUND: Due to high recurrence rate after subtotal thyroidectomy, most of centers have shifted to total thyroidectomy as a surgical treatment for benign multinodular goiter (BMNG), but serious complications, as laryngeal nerve affection & hypocalcaemia, are still present. This study aimed to evaluate treatment of BMNG using intra-capsular total thyroid enucleation in comparison to standard total thyroidectomy. PATIENTS &METHODS: This is a prospective randomized controlled clinical trial conducted in a hospital in the period from December 2009 to December 2015...
July 18, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28728245/-prophylactic-thyroidectomy-in-two-children-indentified-ret-germline-mutations-with-multiple-endocrine-neoplasia-type-2a
#15
Y J Pang, X H Chen, J Y Zhang, Z Dong, S F Wu, F F Zhang, J L Gao
No abstract text is available yet for this article.
July 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28727204/comparison-of-thyroid-fine-needle-aspiration-biopsy-results-before-and-after-implementation-of-bethesda-classification
#16
D Ozdemir, N Bestepe, S Faki, A Kilicarslan, O Parlak, R Ersoy, B Cakir
OBJECTIVE: The Bethesda classification was introduced in 2008 to provide standardisation in the evaluation of thyroid fine needle aspiration cytology (FNAC). We compared the diagnostic value of pre-Bethesda and Bethesda classification systems in the differentiation of benign and malignant thyroid nodules. METHODS: Medical records of patients who underwent a thyroidectomy between June 2007 and June 2014 were reviewed retrospectively. Nodules evaluated with FNAC before March 2010 were classified as pre-Bethesda (non-diagnostic, benign, indeterminate, suspicious for malignancy and malignant), and those evaluated after March 2010 were considered Bethesda (non-diagnostic, benign, atypia of undetermined significance/follicular lesion of undetermined significance, follicular neoplasia/suspicious for follicular neoplasia, suspicious for malignancy and malignant)...
July 20, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/28726141/transoral-robotic-thyroidectomy-lessons-learned-from-an-initial-consecutive-series-of-24-patients
#17
Hoon Yub Kim, Young Jun Chai, Gianlorenzo Dionigi, Angkoon Anuwong, Jeremy D Richmon
BACKGROUND: Transoral thyroid surgery is an ideal method for minimally invasive thyroidectomy, as there is less flap dissection during the procedure and no postoperative scars. Nonetheless, technical obstacles have precluded the wide dissemination of this procedure. We present the surgical procedures and outcomes of transoral robotic thyroidectomy (TORT). METHODS: From September 2012 to June 2016, we performed TORT at Korea University Hospital. We used three intraoral ports and a single axillary port for the system's four robotic arms...
July 19, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28726134/non-functioning-parathyroid-carcinoma-a-case-report
#18
Nobuyasu Suganuma, Hiroyuki Iwasaki, Satoru Shimizu, Tatsuya Yoshida, Takashi Yamanaka, Izumi Kojima, Haruhiko Yamazaki, Soji Toda, Hirotaka Nakayama, Katsuhiko Masudo, Yasushi Rino, Kae Kawachi, Yohei Miyagi, Akio Miyake, Kenichi Ohashi, Munetaka Masuda
BACKGROUND: Non-functioning parathyroid carcinoma is a rare disease that is difficult to distinguish from other diseases based on the lack of hyperparathyroidism. This is a report of non-functioning parathyroid carcinoma diagnosed by reverse transcription polymerase chain reaction (RT-PCR) targeting parathyroid hormone (PTH) messenger RNA. CASE PRESENTATION: The patient is a 67-year-old male who visited our hospital for the chief complaint of hoarseness. A 5-cm mass was observed in the right lobe of the thyroid gland, and poorly differentiated thyroid carcinoma was suspected according to the fine-needle biopsy results...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28717869/transoral-endoscopic-thyroidectomy-vestibular-approach-toetva-indications-techniques-and-results
#19
Angkoon Anuwong, Thanyawat Sasanakietkul, Pornpeera Jitpratoom, Khwannara Ketwong, Hoon Yub Kim, Gianlorenzo Dionigi, Jeremy D Richmon
INTRODUCTION: The Transoral Neck Surgery (TONS) Study Group was established at the 1st International Thyroid NOTES Conference in February 2016 with the intention of standardizing and refining thyroid NOTES techniques, including both transoral endoscopic and robotic thyroidectomy approaches. Herein, the authors report the modification of indications, preparation, and step-by-step explanations for operative techniques, as well as results and postoperative care for transoral endoscopic thyroidectomy vestibular approach (TOETVA)...
July 17, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28715809/thyroid-surgery-to-drain-or-not-to-drain-that-is-the-problem-a-randomized-clinical-trial
#20
Mario Schietroma, Beatrice Pessia, Zuleyka Bianchi, Fabiola De Vita, Francesco Carlei, Stefano Guadagni, Gianfranco Amicucci, Marco Clementi
PURPOSE: We conducted a prospective, randomized study to evaluate the necessity of drainage after thyroid surgery. METHODS: The patients (n = 215) were randomly assigned to be treated with suction drains (group 1; n = 108) or not (group 2; n = 107). RESULTS: The postoperative pain scores were significantly lower in the non-drained group than in the drained group of patients at postoperative days 0 and at 1. Hematomas, seromas, wound infections, transient biochemical hypoparathyroidism, and transient damage of the recurrent laryngeal nerve occurred more frequently in the drained group than in the non-drained group...
July 15, 2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
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