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Parathyroidectomy

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https://www.readbyqxmd.com/read/28533644/atypical-parathyroid-adenoma-with-multiple-brown-tumors-as-initial-presentation-a-rare-entity
#1
V S Krishna Mohan, Manishi L Narayan, Arun Mukka, Bharath Bachimanchi, Amit Kumar Chowhan, B Vijayalakshmi Devi, Suresh Vaikkakara, Alok Sachan
Brown tumors seen in hyperparathyroidism are rare, non-neoplastic lesions because of abnormal bone metabolism, and they can mimic benign bone tumors or malignancy. Although biopsy is considered as the gold standard for diagnosis, it can be inconclusive. As the diagnosis of brown tumors is often challenging, a high index of suspicion is essential for diagnosis. We present a case of 21-year-old woman who presented with multiple painful bony lesions, which were initially misdiagnosed as fibrous dysplasia. Due to persistent bone pain and deterioration in her physical mobility, she was referred to tertiary care centre...
April 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28530313/-minimally-invasive-parathyroidectomy-mip-under-local-anesthesia-for-treatment-of-primary-hyperparathyroidism-phpt-caused-by-a-single-adenoma
#2
Michael M Krausz, Orwa Younis, Ahmad Mahamid, Miri Bidder, Ricardo Alfici
INTRODUCTION: Minimally Invasive Parathyroidectomy (MIP) has become the treatment of choice of Primary Hyperparathyroidism (PHPT) caused by an adenoma. In the present investigation we describe our experience with MIP performed under local anesthesia. METHODS: MIP was performed on 454 of 496 patients (91.5%) with PHPT. In 170 patients (37.4%), MIP was accomplished under local anesthesia. This procedure was elected when the medical condition prohibited general anesthesia, or in accordance with the patient's request...
January 2017: Harefuah
https://www.readbyqxmd.com/read/28527123/clinical-profile-of-juvenile-primary-hyperparathyroidism-a-prospective-study
#3
Federica Saponaro, Claudio Marcocci, Federica Cacciatore, Mario Miccoli, Elena Pardi, Simona Borsari, Gabriele Materazzi, Paolo Miccoli, Filomena Cetani
INTRODUCTION: Juvenile primary hyperparathyroidism is uncommon and more symptomatic than the adult counterpart. The aim of this prospective monocentric study, conducted in a tertiary referral center, was to evaluate the clinical, biochemical, and densitometric data, and the outcome of a series of patients with juvenile primary hyperparathyroidism. MATERIAL AND METHODS: The study group included 154 patients with sporadic and familial juvenile primary hyperparathyroidism, aged ≤40 years...
May 20, 2017: Endocrine
https://www.readbyqxmd.com/read/28522130/primary-hyperparathyroidism-hypercalciuria-and-bone-recovery-after-parathyroidectomy
#4
Inga-Lena Nilsson, Sophie Norenstedt, Jan Zedenius, Ylva Pernow, Robert Bränström
BACKGROUND: In primary hyperparathyroidism, successful parathyroidectomy leads to improved bone mineral density in the majority of cases. Our aim was to further explore the relationship between hypercalciuria, kidney function, and bone recovery after parathyroidectomy. METHODS: Bone mineral density, estimated glomerular filtration rate, and 24-hour urinary calcium were analyzed before and one year after parathyroidectomy in a cohort of 150 primary hyperparathyroidism patients (119 women; median age 60 [range 30-80] years) taking part in a clinical trial...
May 15, 2017: Surgery
https://www.readbyqxmd.com/read/28518414/systematic-review-of-surgical-and-medical-treatment-for-tertiary-hyperparathyroidism
#5
REVIEW
R R Dulfer, G J H Franssen, D A Hesselink, E J Hoorn, C H J van Eijck, T M van Ginhoven
BACKGROUND: A significant proportion of patients with chronic kidney disease and secondary hyperparathyroidism (HPT) remain hyperparathyroid after kidney transplantation, a state known as tertiary HPT. Without treatment, tertiary HPT can lead to diminished kidney allograft and patient survival. Parathyroidectomy was commonly performed to treat tertiary HPT until the introduction of the calcimimetic drug, cinacalcet. It is not known whether surgery or medical treatment is superior for tertiary HPT...
June 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28516785/measurement-of-intact-parathormone-during-operation-for-primary-hyperparathyroidism
#6
P Libansky, S Adamek, P Broulik, M Fialova, J Kubinyi, J Sedy, P Pafko, D Yershov, R Lischke
In this prospective study, the role of the intact parathormone (iPHT) levels for the verification of pathologic parathyroid tissue removal during parathyroidectomy, was analyzed in 441 patients diagnosed with primary hyperparathyroidism. The level of intact parathormone was obtained before the initial incision (baseline level) and 10 minutes after the pathologic parathyroid gland removal (control value). In 80 % of cases, the decrease of intact parathormone was more than 50 % of the baseline level. The comparison of preoperative and postoperative intact parathormone levels can also be used as marker of parathyroid hyperplasia or persistent hyperparathyroidism...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/28515208/glucocorticoid-responsive-lymphocytic-parathyroiditis-and-hypocalciuric-hypercalcemia-due-to-autoantibodies-against-the-calcium-sensing-receptor-a-case-report-and-literature-review
#7
Li Song, Liping Liu, R Tyler Miller, Shirley X Yan, Nancy Jackson, Shelby A Holt, Naim M Maalouf
OBJECTIVE: Autoimmune lymphocytic parathyroiditis and acquired hypocalciuric hypercalcemia associated with autoantibodies against the calcium-sensing receptor (anti-CaSR) are rare and poorly understood conditions. Here, we describe a patient with acquired parathyroid hormone (PTH)-dependent hypercalcemia with associated hypocalciuria, found to have true lymphocytic parathyroiditis on histopathology, and circulating anti-CaSR antibodies in serum. DESIGN AND METHODS: A 64-year-old woman was referred to our clinic for persistent hypercalcemia after a subtotal parathyroidectomy...
July 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28513073/early-neurocognitive-improvements-following-parathyroidectomy-for-primary-hyperparathyroidism
#8
Shivani Shah-Becker, Jonathan Derr, Benjamin S Oberman, Aaron Baker, Brian Saunders, Michele M Carr, David Goldenberg
OBJECTIVES: To establish a time frame for postoperative improvements in neurocognitive function in patients who undergo parathyroidectomy for primary hyperparathyroidism by utilizing repeat neuropsychological assessment at multiple time points before and after surgery. STUDY DESIGN: Prospective cohort study. METHODS: A prospective study was conducted at a tertiary academic medical center between August 2014 and December 2015, including 50 patients with primary hyperparathyroidism who underwent parathyroidectomy...
May 16, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28506410/effectiveness-of-intraoperative-parathyroid-monitoring-iopth-in-predicting-a-multiglandular-or-malignant-parathyroid-disease
#9
C Dobrinja, G Santandrea, M Giacca, Elisabetta Stenner, Maurizio Ruscio, Nicolò de Manzini
AIM: The main goal of our study was to confirm the usefulness of intra-operative parathyroid hormone (PTH) monitoring (ioPTH) when using minimally invasive techniques for treatment of sporadic Primary hyperparathyroidism (pHTP). Furthermore, we aimed to evaluate if ioPTH monitoring may help to predict the etiology of primary hyperparathyroidism, especially in malignant or multiglandular parathyroid disease. METHODS: A retrospective review of 125 consecutive patients with pHPT who underwent parathyroidectomy between 2001 and 2016 at the Department of General Surgery was performed...
May 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28501106/concurrent-endocrine-and-other-surgical-procedures-an-institutional-experience
#10
Rachel Morris, Tina W F Yen, Kara Doffek, Azadeh A Carr, Stuart D Wilson, Douglas B Evans, Tracy S Wang
INRODUCTION: The number of endocrine procedures, specifically parathyroidectomy, thyroidectomy, and adrenalectomy, being performed is increasing. There is a paucity of literature on the feasibility of combining these procedures with other surgical procedures. Therefore, the aim of this study was to determine the effect of performing concurrent surgical procedures on postoperative outcomes. METHODS: This is a single institution retrospective review of multiple prospectively maintained databases of patients who underwent elective thyroidectomy, parathyroidectomy, and/or adrenalectomy in combination with another procedure...
May 1, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28493416/parathyroidectomy-for-the-treatment-of-hyperparathyroidism-thirty-day-morbidity-and-mortality
#11
Jessica A Tang, Anna M Salapatas, Lauren B Bonzelaar, Michael Friedman
OBJECTIVES/HYPOTHESIS: Evaluate morbidity and mortality rates for patients with different levels of hyperparathyroidism (HPT) undergoing parathyroidectomy (PTX), specifically comparing primary hyperparathyroidism to secondary and tertiary hyperparathyroidism. Assess predictive factors of increased morbidity and mortality. STUDY DESIGN: Retrospective national database review. METHODS: Patients undergoing PTX, defined by Current Procedural Terminology codes 60500, 60502, 60505, for the treatment of HPT, were identified in the American College of Surgeons National Surgical Quality Improvement Program database between 2006 and 2014...
May 11, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28489181/early-postoperative-parathormone-sampling-and-prognosis-after-total-parathyroidectomy-in-secondary-hyperparathyroidism
#12
Climério Pereira do Nascimento, Marília D'Elboux Guimarães Brescia, Melani Ribeiro Custódio, Ledo Mazzei Massoni, André Albuquerque Silveira, Patrícia Taschner Goldenstein, Sérgio Samir Arap, Vanda Jorgetti, Rosa Maria Affonso Moyses, Fábio Luiz de Menezes Montenegro
Introduction: There is possibility of a supernumerary hyperplastic parathyroid gland in dialysis patients after total parathyroidectomy and autograft in dialysis patients. Objective: To test if the early postoperative measure of parathyroid hormone (PTH) can identify persistent hyperparathyroidism. Methods: A prospective cohort of dialysis patients submitted to parathyroidectomy had PTH measured up to one week after operation. The absolute value and the relative decrease were analyzed according to clinical outcome of satisfactory control of secondary hyperparathyroidism or persistence...
April 27, 2017: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/28488572/acute-hypocalcemia-following-kidney-transplantation-may-depend-on-the-type-of-remote-parathyroidectomy-a-retrospective-cohort-study%C3%A2
#13
Malorie Simons, Josef Bautista, Rachel Occhiogrosso, Lori Scott-Sheldon, Reginald Gohh
BACKGROUND: Secondary hyperparathyroidism is a common complication of chronic kidney disease. When medical management fails, parathyroidectomy (PTX) is a treatment option. The two most common types are subtotal PTX and total PTX with autotransplantation (AT). To date, there is no consensus as to which procedure is preferable, especially in patients who are candidates for future kidney transplantation. The aim of this study was to identify if the type of PTX is a risk factor for acute postrenal transplant (postRTX) hypocalcemia and a concern for problems with long-term calcium homeostasis...
May 10, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/28486895/severe-hyperkalaemia-complicating-parathyroidectomy-in-patients-with-end-stage-renal-disease
#14
M Pauling, J C Lee, J W Serpell, S Wilson
We evaluated the incidence of perioperative hyperkalaemia in end-stage renal disease (ESRD) patients undergoing parathyroidectomy and investigated possible contributors to this phenomenon. This was a retrospective cohort study looking at patients who had undergone parathyroidectomy for chronic kidney disease-associated mineral bone disease (CKD-MBD) at The Alfred Hospital, Melbourne, since 2001. Baseline demographics including age, gender, aetiology of renal failure and mode of renal replacement therapy as well as anaesthetic technique and duration of surgery were studied as possible contributors...
May 2017: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/28474427/robotic-thyroidectomy-and-parathyroidectomy-an-initial-experience-with-retroauricular-approach
#15
Mohammed Alshehri, Hossam Eldin Mohamed, Thomas Moulthrop, Emad Kandil
BACKGROUND: New approaches for robotic-assisted thyroidectomy were recently described. The purpose of this study was to present the report of our initial experience using a retroauricular approach for thyroid and parathyroid surgeries. METHODS: This is a prospective study that was conducted under institutional review board approval and all surgeries were performed by a single surgeon at a North American academic institution. Some patients underwent an additional concomitant neck lift surgery in addition to the thyroid surgery...
May 5, 2017: Head & Neck
https://www.readbyqxmd.com/read/28467621/intraoperative-nerve-monitoring-during-parathyroid-surgery-the-fort-worth-experience
#16
Moustafa Mourad, Sameep Kadakia, Ameya Jategaonkar, Eli Gordin, Yadranko Ducic
BACKGROUND: Avoidance of recurrent laryngeal nerve (RLN) injury during parathyroid surgery is of paramount important. The purpose of this study was to determine if intraoperative nerve monitoring allowed for decreased rates of RLN injury during parathyroid surgery. METHOD: Between 1997 and 2016, 213 patients undergoing parathyroidectomy were retrospectively analyzed to determine postoperative recurrent nerve injury. Eighty-seven patients did not have intraoperative nerve monitoring, whereas 126 patients did...
May 3, 2017: Head & Neck
https://www.readbyqxmd.com/read/28465501/preoperative-localization-of-parathyroid-adenoma-in-video-assisted-era-is-better-cervical-ultrasound-or-99mtc-sesta-mibi-scintigraphy
#17
Belinda DE Simone, Paolo Del Rio, Fausto Catena, Gaia Fallani, Cino Bendinelli, Josephine A Napoli, Alberto Zaccaroni, Mario Sianesi
BACKGROUND: Endocrine surgeon localizes solitary adenoma (SA) in preoperative time by cervical ultrasound (c-US) and/or 99mTC Sesta MIBI scintigraphy (MIBI-S), but in clinical practice they often show discordant results. The aim of our study is to verify if c-US and MIBI-S have different sensitivity in preoperative localization of SA, depending on its localization, in planning minimally-invasive video-assisted parathyroidectomy (MIVAP). METHODS: This is a retrospective analysis of data (demographics data, preoperative localization of SA by US and MIBI-S, presence of associated thyroid disease, preoperative calcemia, preoperative serum PTH, surgical time, intraoperative PTH values, day 1 postoperative calcemia, definitive histological report) about patients consecutively submitted to MIVAP because of SA between January 2011 and January 2014 in the department of endocrine and general surgery of the University Hospital of Parma (Italy)...
May 2, 2017: Minerva Chirurgica
https://www.readbyqxmd.com/read/28462656/peripherally-inserted-central-catheters-for-calcium-requirements-after-successful-parathyroidectomy-a-comparison-with-centrally-inserted-catheters
#18
H J Qi, W W Yang, L D Zhang, X J Shi, Q Y Li, T Ye
BACKGROUND Intravenous calcium supplements are often required following parathyroidectomy to avoid postoperative hypocalcaemia. The aim of this study was to compare application effect of a femoral central venous catheter (CVC) and peripherally inserted central catheter (PICC) on intravenous calcium supplements after parathyroidectomy. METHODS We retrospectively reviewed the hospital records of 73 patients with secondary hyperparathyroidism who underwent a successful parathyroidectomy at the Huashan Hospital attached to Fudan University between 1 April 2011 and 1 February 2016...
May 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28462641/the-utility-of-the-radionuclide-probe-in-parathyroidectomy-for-primary-hyperparathyroidism
#19
M S Lim, M Jinih, C H Ngai, N M Foley, H P Redmond
INTRODUCTION Parathyroidectomy is the definitive treatment for primary hyperparathyroidism but the intraoperative identification of adenomas is challenging. The aim of this study was to evaluate the utility of a radionuclide probe (RNP) in addition to intraoperative parathyroid hormone ( IOPTH) measurement as an intraoperative diagnostic adjunct in patients undergoing parathyroidectomy for primary hyperparathyroidism. METHODS This was a retrospective cohort study of patients treated between 2004 and 2015 in a university affiliated teaching hospital...
May 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28457397/parathyroidectomy-in-persistent-post-transplantation-hyperparathyroidism-single-center-experience
#20
C Meng, P Martins, J Frazão, M Pestana
BACKGROUND: Hyperparathyroidism is a common complication in chronic kidney disease and might persist in up to 25% of patients after transplantation. In this setting, vitamin D analogues further aggravate persistent hypercalcemia and cinacalcet has not been approved for these patients, some of whom will require parathyroidectomy to correct post-transplantation hyperparathyroidism. OBJECTIVES: In this single-center, retrospective study we aimed to analyze the long-term effect of parathyroidectomy on calcium, phosphorus, and parathyroid hormone (PTH) levels and its effect on allograft function in kidney transplantation patients submitted to parathyroidectomy...
May 2017: Transplantation Proceedings
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