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https://www.readbyqxmd.com/read/28806989/maximising-value-from-a-united-kingdom-biomedical-research-centre-study-protocol
#1
Trisha Greenhalgh, Pavel V Ovseiko, Nick Fahy, Sara Shaw, Polly Kerr, Alexander D Rushforth, Keith M Channon, Vasiliki Kiparoglou
BACKGROUND: Biomedical Research Centres (BRCs) are partnerships between healthcare organisations and universities in England. Their mission is to generate novel treatments, technologies, diagnostics and other interventions that increase the country's international competitiveness, to rapidly translate these innovations into benefits for patients, and to improve efficiency and reduce waste in healthcare. As NIHR Oxford BRC (Oxford BRC) enters its third 5-year funding period, we seek to (1) apply the evidence base on how best to support the various partnerships in this large, multi-stakeholder research system and (2) research how these partnerships play out in a new, ambitious programme of translational research...
August 14, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/28801403/equipping-community-pharmacy-workers-as-agents-for-health-behaviour-change-developing-and-testing-a-theory-based-smoking-cessation-intervention
#2
Liz Steed, Ratna Sohanpal, Wai-Yee James, Carol Rivas, Sandra Jumbe, Angel Chater, Adam Todd, Elizabeth Edwards, Virginia Macneil, Fraser Macfarlane, Trisha Greenhalgh, Chris Griffiths, Sandra Eldridge, Stephanie Taylor, Robert Walton
OBJECTIVE: To develop a complex intervention for community pharmacy staff to promote uptake of smoking cessation services and to increase quit rates. DESIGN: Following the Medical Research Council framework, we used a mixed-methods approach to develop, pilot and then refine the intervention. METHODS: Phase I: We used information from qualitative studies in pharmacies, systematic literature reviews and the Capability, Opportunity, Motivation-Behaviour framework to inform design of the initial version of the intervention...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28687532/studying-scale-up-and-spread-as-social-practice-theoretical-introduction-and-empirical-case-study
#3
James Shaw, Sara Shaw, Joseph Wherton, Gemma Hughes, Trisha Greenhalgh
BACKGROUND: Health and care technologies often succeed on a small scale but fail to achieve widespread use (scale-up) or become routine practice in other settings (spread). One reason for this is under-theorization of the process of scale-up and spread, for which a potentially fruitful theoretical approach is to consider the adoption and use of technologies as social practices. OBJECTIVE: This study aimed to use an in-depth case study of assisted living to explore the feasibility and usefulness of a social practice approach to explaining the scale-up of an assisted-living technology across a local system of health and social care...
July 7, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28663428/books-challenging-perspectives-on-organizational-change-in-health-care-change-in-the-right-way
#4
Trisha Greenhalgh
No abstract text is available yet for this article.
July 2017: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/28637744/group-clinics-for-young-adults-with-diabetes-in-an-ethnically-diverse-socioeconomically-deprived-setting-together-study-protocol-for-a-realist-review-co-design-and-mixed-methods-participatory-evaluation-of-a-new-care-model
#5
Chrysanthi Papoutsi, Dougal Hargreaves, Grainne Colligan, Ann Hagell, Anita Patel, Desirée Campbell-Richards, Russell M Viner, Shanti Vijayaraghavan, Martin Marshall, Trisha Greenhalgh, Sarah Finer
INTRODUCTION: Young adults with diabetes often report dissatisfaction with care and have poor diabetes-related health outcomes. As diabetes prevalence continues to rise, group-based care could provide a sustainable alternative to traditional one-to-one consultations, by engaging young people through life stage-, context- and culturally-sensitive approaches. In this study, we will co-design and evaluate a group-based care model for young adults with diabetes and complex health and social needs in socioeconomically deprived areas...
June 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28615004/understanding-heart-failure-explaining-telehealth-a-hermeneutic-systematic-review
#6
Trisha Greenhalgh, Christine A'Court, Sara Shaw
BACKGROUND: Enthusiasts for telehealth extol its potential for supporting heart failure management. But randomised trials have been slow to recruit and produced conflicting findings; real-world roll-out has been slow. We sought to inform policy by making sense of a complex literature on heart failure and its remote management. METHODS: Through database searching and citation tracking, we identified 7 systematic reviews of systematic reviews, 32 systematic reviews (including 17 meta-analyses and 8 qualitative reviews); six mega-trials and over 60 additional relevant empirical studies and commentaries...
June 14, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28450337/books-evaluative-research-methods-managing-the-complexities-of-judgment-in-the-field-evaluation-for-social-justice
#7
Trisha Greenhalgh
No abstract text is available yet for this article.
May 2017: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/28369935/phase-2-of-catalise-a-multinational-and-multidisciplinary-delphi-consensus-study-of-problems-with-language-development-terminology
#8
Dorothy V M Bishop, Margaret J Snowling, Paul A Thompson, Trisha Greenhalgh
BACKGROUND: Lack of agreement about criteria and terminology for children's language problems affects access to services as well as hindering research and practice. We report the second phase of a study using an online Delphi method to address these issues. In the first phase, we focused on criteria for language disorder. Here we consider terminology. METHODS: The Delphi method is an iterative process in which an initial set of statements is rated by a panel of experts, who then have the opportunity to view anonymised ratings from other panel members...
March 30, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28351391/the-impact-on-healthcare-policy-and-practice-from-36-multi-project-research-programmes-findings-from-two-reviews
#9
REVIEW
Steve Hanney, Trisha Greenhalgh, Amanda Blatch-Jones, Matthew Glover, James Raftery
BACKGROUND: We sought to analyse the impacts found, and the methods used, in a series of assessments of programmes and portfolios of health research consisting of multiple projects. METHODS: We analysed a sample of 36 impact studies of multi-project research programmes, selected from a wider sample of impact studies included in two narrative systematic reviews published in 2007 and 2016. We included impact studies in which the individual projects in a programme had been assessed for wider impact, especially on policy or practice, and where findings had been described in such a way that allowed them to be collated and compared...
March 28, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/28052845/efficacy-and-effectiveness-of-screen-and-treat-policies-in-prevention-of-type-2-diabetes-systematic-review-and-meta-analysis-of-screening-tests-and-interventions
#10
REVIEW
Eleanor Barry, Samantha Roberts, Jason Oke, Shanti Vijayaraghavan, Rebecca Normansell, Trisha Greenhalgh
OBJECTIVES:  To assess diagnostic accuracy of screening tests for pre-diabetes and efficacy of interventions (lifestyle or metformin) in preventing onset of type 2 diabetes in people with pre-diabetes. DESIGN:  Systematic review and meta-analysis. DATA SOURCES AND METHOD:  Medline, PreMedline, and Embase. Study protocols and seminal papers were citation-tracked in Google Scholar to identify definitive trials and additional publications...
January 4, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27978837/what-works-for-whom-in-pharmacist-led-smoking-cessation-support-realist-review
#11
REVIEW
Trisha Greenhalgh, Fraser Macfarlane, Liz Steed, Robert Walton
BACKGROUND: New models of primary care are needed to address funding and staffing pressures. We addressed the research question "what works for whom in what circumstances in relation to the role of community pharmacies in providing lifestyle interventions to support smoking cessation?" METHODS: This is a realist review conducted according to RAMESES standards. We began with a sample of 103 papers included in a quantitative review of community pharmacy intervention trials identified through systematic searching of seven databases...
December 16, 2016: BMC Medicine
https://www.readbyqxmd.com/read/27925823/systematic-reviews-for-policymaking-muddling-through
#12
Trisha Greenhalgh, Kirsti Malterud
No abstract text is available yet for this article.
January 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/27869112/a-brief-overview-of-english-primary-care-in-the-last-half-century
#13
Carlota Blanco Rubio, Carmen de Francisco Montero, Francisco Javier González Hernández, Alberto Adrada Bautista, Inmaculada Gabaldón-Rodríguez, Manuel Ortega-Calvo
Key hefts, the hard core of clinical profile, scientific nursing and nowadays of the English School of Primary Care in the last sixty years are revisited. We understand that the most profound intellectual influence has been to Archie Cochrane, among family physicians hard core components we include John Fry (1922-1994), David Metcalfe and Julian Tudor Hart. On the other hand, Lisbeth Hockey (1918-2004), PhD in Nursing, was responsible for several years of Nursing Research Unit at the University of Edinburgh...
November 21, 2016: Revista Española de Salud Pública
https://www.readbyqxmd.com/read/27789487/blood-pressure-measurement-a-call-to-arms
#14
EDITORIAL
Christine A'Court, James Sheppard, Trisha Greenhalgh
No abstract text is available yet for this article.
November 2016: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/27432056/a-global-call-for-action-to-include-gender-in-research-impact-assessment
#15
Pavel V Ovseiko, Trisha Greenhalgh, Paula Adam, Jonathan Grant, Saba Hinrichs-Krapels, Kathryn E Graham, Pamela A Valentine, Omar Sued, Omar F Boukhris, Nada M Al Olaqi, Idrees S Al Rahbi, Anne-Maree Dowd, Sara Bice, Tamika L Heiden, Michael D Fischer, Sue Dopson, Robyn Norton, Alexandra Pollitt, Steven Wooding, Gert V Balling, Ulla Jakobsen, Ellen Kuhlmann, Ineke Klinge, Linda H Pololi, Reshma Jagsi, Helen Lawton Smith, Henry Etzkowitz, Mathias W Nielsen, Carme Carrion, Maite Solans-Domènech, Esther Vizcaino, Lin Naing, Quentin H N Cheok, Baerbel Eckelmann, Moses C Simuyemba, Temwa Msiska, Giovanna Declich, Laurel D Edmunds, Vasiliki Kiparoglou, Alison M J Buchan, Catherine Williamson, Graham M Lord, Keith M Channon, Rebecca Surender, Alastair M Buchan
Global investment in biomedical research has grown significantly over the last decades, reaching approximately a quarter of a trillion US dollars in 2010. However, not all of this investment is distributed evenly by gender. It follows, arguably, that scarce research resources may not be optimally invested (by either not supporting the best science or by failing to investigate topics that benefit women and men equitably). Women across the world tend to be significantly underrepresented in research both as researchers and research participants, receive less research funding, and appear less frequently than men as authors on research publications...
July 19, 2016: Health Research Policy and Systems
https://www.readbyqxmd.com/read/27392128/catalise-a-multinational-and-multidisciplinary-delphi-consensus-study-identifying-language-impairments-in-children
#16
D V M Bishop, Margaret J Snowling, Paul A Thompson, Trisha Greenhalgh
Delayed or impaired language development is a common developmental concern, yet there is little agreement about the criteria used to identify and classify language impairments in children. Children's language difficulties are at the interface between education, medicine and the allied professions, who may all adopt different approaches to conceptualising them. Our goal in this study was to use an online Delphi technique to see whether it was possible to achieve consensus among professionals on appropriate criteria for identifying children who might benefit from specialist services...
2016: PloS One
https://www.readbyqxmd.com/read/27352795/clinical-encounters-in-the-post-guidelines-era
#17
Glyn Elwyn, Siestse Wieringa, Trisha Greenhalgh
No abstract text is available yet for this article.
June 27, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27265562/achieving-research-impact-through-co-creation-in-community-based-health-services-literature-review-and-case-study
#18
REVIEW
Trisha Greenhalgh, Claire Jackson, Sara Shaw, Tina Janamian
POLICY POINTS: Co-creation-collaborative knowledge generation by academics working alongside other stakeholders-is an increasingly popular approach to aligning research and service development. It has potential for "moving beyond the ivory towers" to deliver significant societal impact via dynamic, locally adaptive community-academic partnerships. Principles of successful co-creation include a systems perspective, a creative approach to research focused on improving human experience, and careful attention to governance and process...
June 2016: Milbank Quarterly
https://www.readbyqxmd.com/read/27260370/uncertainty-and-objectivity-in-clinical-decision-making-a-clinical-case-in-emergency-medicine
#19
Eivind Engebretsen, Kristin Heggen, Sietse Wieringa, Trisha Greenhalgh
The evidence-based practice and evidence-based medicine (EBM) movements have promoted standardization through guideline development methodologies based on systematic reviews and meta-analyses of best available research. EBM has challenged clinicians to question their reliance on practical reasoning and clinical judgement. In this paper, we argue that the protagonists of EBM position their mission as reducing uncertainty through the use of standardized methods for knowledge evaluation and use. With this drive towards uniformity, standardization and control comes a suspicion towards intuition, creativity and uncertainty as integral parts of medical practice...
December 2016: Medicine, Health Care, and Philosophy
https://www.readbyqxmd.com/read/27211576/research-impact-a-narrative-review
#20
REVIEW
Trisha Greenhalgh, James Raftery, Steve Hanney, Matthew Glover
Impact occurs when research generates benefits (health, economic, cultural) in addition to building the academic knowledge base. Its mechanisms are complex and reflect the multiple ways in which knowledge is generated and utilised. Much progress has been made in measuring both the outcomes of research and the processes and activities through which these are achieved, though the measurement of impact is not without its critics. We review the strengths and limitations of six established approaches (Payback, Research Impact Framework, Canadian Academy of Health Sciences, monetisation, societal impact assessment, UK Research Excellence Framework) plus recently developed and largely untested ones (including metrics and electronic databases)...
May 23, 2016: BMC Medicine
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