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Trisha greenhalgh

Pavel V Ovseiko, Trisha Greenhalgh, Paula Adam, Jonathan Grant, Saba Hinrichs-Krapels, Kathryn E Graham, Pamela A Valentine, Omar Sued, Omar F Boukhris, Nada M Al Olaqi, Idrees S Al Rahbi, Anne-Maree Dowd, Sara Bice, Tamika L Heiden, Michael D Fischer, Sue Dopson, Robyn Norton, Alexandra Pollitt, Steven Wooding, Gert V Balling, Ulla Jakobsen, Ellen Kuhlmann, Ineke Klinge, Linda H Pololi, Reshma Jagsi, Helen Lawton Smith, Henry Etzkowitz, Mathias W Nielsen, Carme Carrion, Maite Solans-Domènech, Esther Vizcaino, Lin Naing, Quentin H N Cheok, Baerbel Eckelmann, Moses C Simuyemba, Temwa Msiska, Giovanna Declich, Laurel D Edmunds, Vasiliki Kiparoglou, Alison M J Buchan, Catherine Williamson, Graham M Lord, Keith M Channon, Rebecca Surender, Alastair M Buchan
Global investment in biomedical research has grown significantly over the last decades, reaching approximately a quarter of a trillion US dollars in 2010. However, not all of this investment is distributed evenly by gender. It follows, arguably, that scarce research resources may not be optimally invested (by either not supporting the best science or by failing to investigate topics that benefit women and men equitably). Women across the world tend to be significantly underrepresented in research both as researchers and research participants, receive less research funding, and appear less frequently than men as authors on research publications...
2016: Health Research Policy and Systems
D V M Bishop, Margaret J Snowling, Paul A Thompson, Trisha Greenhalgh
Delayed or impaired language development is a common developmental concern, yet there is little agreement about the criteria used to identify and classify language impairments in children. Children's language difficulties are at the interface between education, medicine and the allied professions, who may all adopt different approaches to conceptualising them. Our goal in this study was to use an online Delphi technique to see whether it was possible to achieve consensus among professionals on appropriate criteria for identifying children who might benefit from specialist services...
2016: PloS One
Glyn Elwyn, Siestse Wieringa, Trisha Greenhalgh
No abstract text is available yet for this article.
2016: BMJ: British Medical Journal
Trisha Greenhalgh, Claire Jackson, Sara Shaw, Tina Janamian
POLICY POINTS: Co-creation-collaborative knowledge generation by academics working alongside other stakeholders-is an increasingly popular approach to aligning research and service development. It has potential for "moving beyond the ivory towers" to deliver significant societal impact via dynamic, locally adaptive community-academic partnerships. Principles of successful co-creation include a systems perspective, a creative approach to research focused on improving human experience, and careful attention to governance and process...
June 2016: Milbank Quarterly
Eivind Engebretsen, Kristin Heggen, Sietse Wieringa, Trisha Greenhalgh
The evidence-based practice and evidence-based medicine (EBM) movements have promoted standardization through guideline development methodologies based on systematic reviews and meta-analyses of best available research. EBM has challenged clinicians to question their reliance on practical reasoning and clinical judgement. In this paper, we argue that the protagonists of EBM position their mission as reducing uncertainty through the use of standardized methods for knowledge evaluation and use. With this drive towards uniformity, standardization and control comes a suspicion towards intuition, creativity and uncertainty as integral parts of medical practice...
June 3, 2016: Medicine, Health Care, and Philosophy
Trisha Greenhalgh, James Raftery, Steve Hanney, Matthew Glover
Impact occurs when research generates benefits (health, economic, cultural) in addition to building the academic knowledge base. Its mechanisms are complex and reflect the multiple ways in which knowledge is generated and utilised. Much progress has been made in measuring both the outcomes of research and the processes and activities through which these are achieved, though the measurement of impact is not without its critics. We review the strengths and limitations of six established approaches (Payback, Research Impact Framework, Canadian Academy of Health Sciences, monetisation, societal impact assessment, UK Research Excellence Framework) plus recently developed and largely untested ones (including metrics and electronic databases)...
2016: BMC Medicine
Laurel D Edmunds, Pavel V Ovseiko, Sasha Shepperd, Trisha Greenhalgh, Peggy Frith, Nia W Roberts, Linda H Pololi, Alastair M Buchan
Women are under-represented in academic medicine. We reviewed the empirical evidence focusing on the reasons for women's choice or rejection of careers in academic medicine. Using a systematic search, we identified 52 studies published between 1985, and 2015. More than half had methodological limitations and most were from North America. Eight main themes were explored in these studies. There was consistent evidence for four of these themes: women are interested in teaching more than in research; participation in research can encourage women into academic medicine; women lack adequate mentors and role models; and women experience gender discrimination and bias...
April 19, 2016: Lancet
Olga P Nyssen, Stephanie J C Taylor, Geoff Wong, Elizabeth Steed, Liam Bourke, Joanne Lord, Carol A Ross, Sheila Hayman, Victoria Field, Ailish Higgins, Trisha Greenhalgh, Catherine Meads
BACKGROUND: Writing therapy to improve physical or mental health can take many forms. The most researched model of therapeutic writing (TW) is unfacilitated, individual expressive writing (written emotional disclosure). Facilitated writing activities are less widely researched. DATA SOURCES: Databases, including MEDLINE, EMBASE, PsycINFO, Linguistics and Language Behaviour Abstracts, Allied and Complementary Medicine Database and Cumulative Index to Nursing and Allied Health Literature, were searched from inception to March 2013 (updated January 2015)...
April 2016: Health Technology Assessment: HTA
Cameron David Willis, Jessie Saul, Helen Bevan, Mary Ann Scheirer, Allan Best, Trisha Greenhalgh, Russell Mannion, Evelyn Cornelissen, David Howland, Emily Jenkins, Jennifer Bitz
PURPOSE: The questions addressed by this review are: first, what are the guiding principles underlying efforts to stimulate sustained cultural change; second, what are the mechanisms by which these principles operate; and, finally, what are the contextual factors that influence the likelihood of these principles being effective? The paper aims to discuss these issues. DESIGN/METHODOLOGY/APPROACH: The authors conducted a literature review informed by rapid realist review methodology that examined how interventions interact with contexts and mechanisms to influence the sustainability of cultural change...
2016: Journal of Health Organization and Management
Trisha Greenhalgh, Sara Shaw, Joe Wherton, Gemma Hughes, Jenni Lynch, Christine A'Court, Sue Hinder, Nick Fahy, Emma Byrne, Alexander Finlayson, Tom Sorell, Rob Procter, Rob Stones
INTRODUCTION: Research to date into assisted living technologies broadly consists of 3 generations: technical design, experimental trials and qualitative studies of the patient experience. We describe a fourth-generation paradigm: studies of assisted living technologies in their organisational, social, political and policy context. Fourth-generation studies are necessarily organic and emergent; they view technology as part of a dynamic, networked and potentially unstable system. They use co-design methods to generate and stabilise local solutions, taking account of context...
2016: BMJ Open
Trisha Greenhalgh, Ellen Annandale, Richard Ashcroft, James Barlow, Nick Black, Alan Bleakley, Ruth Boaden, Jeffrey Braithwaite, Nicky Britten, Franco Carnevale, Kath Checkland, Julianne Cheek, Alex Clark, Simon Cohn, Jack Coulehan, Benjamin Crabtree, Steven Cummins, Frank Davidoff, Huw Davies, Robert Dingwall, Mary Dixon-Woods, Glyn Elwyn, Eivind Engebretsen, Ewan Ferlie, Naomi Fulop, John Gabbay, Marie-Pierre Gagnon, Dariusz Galasinski, Ruth Garside, Lucy Gilson, Peter Griffiths, Penny Hawe, Jan-Kees Helderman, Brian Hodges, David Hunter, Margaret Kearney, Celia Kitzinger, Jenny Kitzinger, Ayelet Kuper, Saville Kushner, Andree Le May, France Legare, Lorelei Lingard, Louise Locock, Jill Maben, Mary Ellen Macdonald, Frances Mair, Russell Mannion, Martin Marshall, Carl May, Nicholas Mays, Lorna McKee, Marissa Miraldo, David Morgan, Janice Morse, Sarah Nettleton, Sandy Oliver, Warrren Pearce, Pierre Pluye, Catherine Pope, Glenn Robert, Celia Roberts, Stefania Rodella, Jo Rycroft-Malone, Margarete Sandelowski, Paul Shekelle, Fiona Stevenson, Sharon Straus, Deborah Swinglehurst, Sally Thorne, Göran Tomson, Gerd Westert, Sue Wilkinson, Brian Williams, Terry Young, Sue Ziebland
No abstract text is available yet for this article.
2016: BMJ: British Medical Journal
Sarah Atkins, Celia Roberts, Kamila Hawthorne, Trisha Greenhalgh
BACKGROUND: Assessment of consulting skills using simulated patients is widespread in medical education. Most research into such assessment is sited in a statistical paradigm that focuses on psychometric properties or replicability of such tests. Equally important, but less researched, is the question of how far consultations with simulated patients reflect real clinical encounters--for which sociolinguistics, defined as the study of language in its socio-cultural context, provides a helpful analytic lens...
2016: BMC Medical Education
Felicity Goodyear-Smith, Claire Jackson, Trisha Greenhalgh
BACKGROUND: Implementation science research, especially when using participatory and co-design approaches, raises unique challenges for research ethics committees. Such challenges may be poorly addressed by approval and governance mechanisms that were developed for more traditional research approaches such as randomised controlled trials. DISCUSSION: Implementation science commonly involves the partnership of researchers and stakeholders, attempting to understand and encourage uptake of completed or piloted research...
2015: BMC Medical Ethics
Michael P Kelly, Iona Heath, Jeremy Howick, Trisha Greenhalgh
BACKGROUND: Evidence-based medicine (EBM) has always required integration of patient values with 'best' clinical evidence. It is widely recognized that scientific practices and discoveries, including those of EBM, are value-laden. But to date, the science of EBM has focused primarily on methods for reducing bias in the evidence, while the role of values in the different aspects of the EBM process has been almost completely ignored. DISCUSSION: In this paper, we address this gap by demonstrating how a consideration of values can enhance every aspect of EBM, including: prioritizing which tests and treatments to investigate, selecting research designs and methods, assessing effectiveness and efficiency, supporting patient choice and taking account of the limited time and resources available to busy clinicians...
2015: BMC Medical Ethics
Trisha Greenhalgh
No abstract text is available yet for this article.
October 2015: British Journal of General Practice: the Journal of the Royal College of General Practitioners
Eleanor Barry, Samantha Roberts, Sarah Finer, Shanti Vijayaraghavan, Trisha Greenhalgh
No abstract text is available yet for this article.
2015: BMJ: British Medical Journal
Trisha Greenhalgh, Rosamund Snow, Sara Ryan, Sian Rees, Helen Salisbury
BACKGROUND: Evidence-based medicine (EBM) is maturing from its early focus on epidemiology to embrace a wider range of disciplines and methodologies. At the heart of EBM is the patient, whose informed choices have long been recognised as paramount. However, good evidence-based care is more than choices. DISCUSSION: We discuss six potential 'biases' in EBM that may inadvertently devalue the patient and carer agenda: limited patient input to research design, low status given to experience in the hierarchy of evidence, a tendency to conflate patient-centred consulting with use of decision tools; insufficient attention to power imbalances that suppress the patient's voice, over-emphasis on the clinical consultation, and focus on people who seek and obtain care (rather than the hidden denominator of those that do not seek or cannot access care)...
2015: BMC Medicine
Trisha Greenhalgh, Geoff Wong, Justin Jagosh, Joanne Greenhalgh, Ana Manzano, Gill Westhorp, Ray Pawson
INTRODUCTION: Realist evaluation is an increasingly popular methodology in health services research. For realist evaluations (RE) this project aims to: develop quality and reporting standards and training materials; build capacity for undertaking and critically evaluating them; produce resources and training materials for lay participants, and those seeking to involve them. METHODS: To achieve our aims, we will: (1) Establish management and governance infrastructure; (2) Recruit an interdisciplinary Delphi panel of 35 participants with diverse relevant experience of RE; (3) Summarise current literature and expert opinion on best practice in RE; (4) Run an online Delphi panel to generate and refine items for quality and reporting standards; (5) Capture 'real world' experiences and challenges of RE-for example, by providing ongoing support to realist evaluations, hosting the RAMESES JISCmail list on realist research, and feeding problems and insights from these into the deliberations of the Delphi panel; (6) Produce quality and reporting standards; (7) Collate examples of the learning and training needs of researchers, students, reviewers and lay members in relation to RE; (8) Develop, deliver and evaluate training materials for RE and deliver training workshops; and (9) Develop and evaluate information and resources for patients and other lay participants in RE (eg, draft template information sheets and model consent forms) and; (10) Disseminate training materials and other resources...
2015: BMJ Open
Heather McMullen, Chris Griffiths, Werner Leber, Trisha Greenhalgh
BACKGROUND: Complex intervention trials may require health care organisations to implement new service models. In a recent cluster randomised controlled trial, some participating organisations achieved high recruitment, whereas others found it difficult to assimilate the intervention and were low recruiters. We sought to explain this variation and develop a model to inform organisational participation in future complex intervention trials. METHODS: The trial included 40 general practices in a London borough with high HIV prevalence...
2015: Trials
Joseph Wherton, Paul Sugarhood, Rob Procter, Sue Hinder, Trisha Greenhalgh
BACKGROUND: The low uptake of telecare and telehealth services by older people may be explained by the limited involvement of users in the design. If the ambition of 'care closer to home' is to be realised, then industry, health and social care providers must evolve ways to work with older people to co-produce useful and useable solutions. METHOD: We conducted 10 co-design workshops with users of telehealth and telecare, their carers, service providers and technology suppliers...
2015: Implementation Science: IS
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