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Uterine artery doppler ultrasound

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https://www.readbyqxmd.com/read/28436166/perinatal-loss-at-term-the-role-of-uteroplacental-and-fetal-doppler-assessment
#1
Caitriona Monaghan, Julia Binder, Baskaran Thilaganathan, José Morales-Roselló, Asma Khalil
OBJECTIVE: To examine the association of uterine artery (UtA) Doppler indices and cerebroplacental ratio (CPR) on perinatal outcome at term. METHODS: This retrospective cohort study conducted in a single tertiary referral centre included all singleton pregnancies undergoing ultrasound assessment in the third trimester, which subsequently delivered at term. Fetal biometry and Dopplers including the umbilical artery (UA), middle cerebral artery (MCA) and uterine artery were recorded...
April 24, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28374437/re-impact-of-aspirin-on-trophoblastic-invasion-in-women-with-abnormal-uterine-artery-doppler-at-11-14-weeks-a-randomized-controlled-study-e-scazzocchio-d-oros-d-diaz-j-c-ramirez-m-ricart-e-meler-r-gonz%C3%A3-lez-de-ag%C3%A3-ero-e-gratacos-and-f-figueras-ultrasound-obstet
#2
https://www.readbyqxmd.com/read/28328938/tissue-factor-pathway-inhibitor-for-prediction-of-placenta-mediated-adverse-pregnancy-outcomes-in-high-risk-women-angiopred-study
#3
Aurélie Di Bartolomeo, Céline Chauleur, Jean-Christophe Gris, Céline Chapelle, Edouard Noblot, Silvy Laporte, Tiphaine Raia-Barjat
OBJECTIVE: The study aimed to evaluate if the rate of tissue factor pathway inhibitor during pregnancy and following delivery could be a predictive factor for placenta-mediated adverse pregnancy outcomes in high-risk women. METHODS: This was a prospective multicentre cohort study of 200 patients at a high risk of occurrence or recurrence of placenta-mediated adverse pregnancy outcomes conducted between June 2008 and October 2010. Measurements of tissue factor pathway inhibitor resistance (normalized ratio) and tissue factor pathway inhibitor activity were performed for the last 72 patients at 20, 24, 28, 32, and 36 weeks of gestation and during the postpartum period...
2017: PloS One
https://www.readbyqxmd.com/read/28299220/spontaneous-regression-of-uterine-arteriovenous-malformations-with-conservative-management
#4
Keiko Mekaru, Sugiko Oishi, Kozue Akamine, Chiaki Heshiki, Yoichi Aoki
Uterine arteriovenous malformation (AVM) can cause massive hemorrhage and is often treated with uterine artery embolization (UAE), which may lead to ovarian insufficiency. Thus, avoiding UAE should be considered, particularly in women undergoing fertility treatments. We present three women diagnosed with postmiscarriage AVM on color Doppler by transvaginal ultrasound imaging. They had no genital bleeding and a small mass, measuring 16-22 mm. If estradiol was >300 pg/mL when AVM was diagnosed, then a gonadotropin-releasing hormone agonist was administered...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28153658/first-trimester-alcohol-exposure-alters-placental-perfusion-and-fetal-oxygen-availability-affecting-fetal-growth-and-development-in-a-non-human-primate-model
#5
Jamie O Lo, Matthias C Schabel, Victoria H J Roberts, Xiaojie Wang, Katherine S Lewandowski, Kathleen A Grant, Antonio E Frias, Christopher D Kroenke
BACKGROUND: Prenatal alcohol exposure leads to impaired fetal growth, brain development, and stillbirth. Placental impairment likely contributes to these adverse outcomes, but the mechanisms and specific vasoactive effects of alcohol that links altered placental function to impaired fetal development remain areas of active research. OBJECTIVE: Recently, we developed magnetic resonance imaging techniques in nonhuman primates to characterize placental blood oxygenation through measurements of T2* and perfusion using dynamic contrast-enhanced magnetic resonance imaging...
March 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28130433/the-association-of-maternal-thyroid-function-with-placental-hemodynamics
#6
M Barjaktarovic, T I M Korevaar, L Chaker, V W V Jaddoe, Y B de Rijke, T J Visser, E A P Steegers, R P Peeters
STUDY QUESTION: What is the clinical association of maternal thyroid function with placental hemodynamic function? SUMMARY ANSWER: A higher free thyroxine (FT4) concentration in early pregnancy is associated with higher placental vascular resistance. WHAT IS KNOWN ALREADY: Suboptimal placental function is associated with preeclampsia (which, in turn, further deteriorates placental hemodynamics and impairs the fetal blood supply), fetal growth restriction and premature delivery...
March 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28114884/everrest-prospective-study-a-6-year-prospective-study-to-define-the-clinical-and-biological-characteristics-of-pregnancies-affected-by-severe-early-onset-fetal-growth-restriction
#7
Rebecca Spencer, Gareth Ambler, Jana Brodszki, Anke Diemert, Francesc Figueras, Eduard Gratacós, Stefan R Hansson, Kurt Hecher, Angela Huertas-Ceballos, Neil Marlow, Karel Marsál, Eva Morsing, Donald Peebles, Carlo Rossi, Neil J Sebire, John F Timms, Anna L David
BACKGROUND: Fetal growth restriction (FGR) is a serious obstetric condition for which there is currently no treatment. The EVERREST Prospective Study has been designed to characterise the natural history of pregnancies affected by severe early onset FGR and establish a well phenotyped bio-bank. The findings will provide up-to-date information for clinicians and patients and inform the design and conduct of the EVERREST Clinical Trial: a phase I/IIa trial to assess the safety and efficacy of maternal vascular endothelial growth factor (VEGF) gene therapy in severe early onset FGR...
January 23, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28091544/ultrasound-prediction-of-abnormal-infant-development-in-hypertensive-pregnant-women-in-the-second-and-third-trimester
#8
Guofang Shen, Yajuan Huang, Lixin Jiang, Jinghong Gu, Yaxin Wang, Bing Hu
The objective was to assess the sensitivities and accuracies of Doppler ultrasound parameters in the second and third trimester of hypertensive pregnancies in determining perinatal outcomes. 1,054 pregnancies were retrospectively categorized into three groups (healthy pregnancies (HP, n = 988), pregnancies of hypertensive women (HypP, n = 30) and high-risk hypertension pregnancies (HRHypP, n = 36), depending on gestational hypertension as well as fetal birth weights and pregnancy outcomes. Systolic/diastolic ratio (S/D), resistance index (RI), pulsatility index (PI) of the bilateral uterine artery, umbilical artery and vein as well as venous flow velocity data were monitored by Doppler ultrasound...
January 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28079791/a-possible-new-approach-in-the-prediction-of-late-gestational-hypertension-the-role-of-the-fetal-aortic-intima-media-thickness
#9
Silvia Visentin, Ambrogio P Londero, Martina Camerin, Enrico Grisan, Erich Cosmi
The aim was to determine the predictive role of combined screening for late-onset gestational hypertension by fetal ultrasound measurements, third trimester uterine arteries (UtAs) Doppler imaging, and maternal history. This prospective study on singleton pregnancies was conducted at the tertiary center of Maternal and Fetal Medicine of the University of Padua during the period between January 2012 and December 2014. Ultrasound examination (fetal biometry, fetal wellbeing, maternal Doppler study, fetal abdominal aorta intima-media thickness [aIMT], and fetal kidney volumes), clinical data (mother age, prepregnancy body mass index [BMI], and parity), and pregnancy outcomes were collected...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28038968/combined-use-of-serum-mcp-1-il-10-ratio-and-uterine-artery-doppler-index-significantly-improves-the-prediction-of-preeclampsia
#10
Shihong Cui, Yanan Gao, Linlin Zhang, Yuan Wang, Lindong Zhang, Pingping Liu, Ling Liu, Juan Chen
BACKGROUND: Monocyte chemotactic protein-1 (MCP-1, or CCL2) is a member of the chemokine subfamily involved in recruitment of monocytes in inflammatory tissues. IL-10 is a key regulator for maintaining the balance of anti-inflammatory and pro-inflammatory milieu at the feto-maternal interface. Doppler examination has been routinely performed for the monitoring and management of preeclampsia patients. This study evaluates the efficiency of these factors alone, or in combination, for the predication of preeclampsia...
December 27, 2016: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28012454/prediction-of-low-birth-weight-comparison-of-placental-t2-estimated-by-mri-and-uterine-artery-pulsatility-index
#11
Marianne Sinding, David A Peters, Jens B Frøkjær, Ole B Christiansen, Astrid Petersen, Niels Uldbjerg, Anne Sørensen
OBJECTIVE: Neonates at low birth weight due to placental dysfunction are at high risk of adverse outcomes. These outcomes can be substantially improved by prenatal identification. The Magnetic Resonance Imaging (MRI) constant, placental T2* reflects placental structure and oxygenation and thereby placental function. Therefore, we aimed to evaluate the performance of placental T2* in the prediction of low birth weight using the uterine artery (UtA) pulsatility index (PI) as gold standard...
January 2017: Placenta
https://www.readbyqxmd.com/read/28004439/prediction-of-fetal-growth-restriction-using-estimated-fetal-weight-versus-a-combined-screening-model-at-32-36-weeks-of-gestation
#12
Jezid Miranda, Merida Rodriguez-Lopez, Stefania Triunfo, Mikko Sairanen, Heikki Kouru, Miguel Parra-Saavedra, Francesca Crovetto, Francesc Figueras, Fatima Crispi, Eduard Gratacos
OBJECTIVES: To compare the performance of a third trimester screening based on estimated fetal weight (EFW) versus a combined model composed by maternal baseline characteristics, mean arterial pressure (MAP), ultrasound and biochemical markers for the prediction of smallness for gestational age (SGA) and late-onset fetal growth restriction (FGR). METHODS: Nested case-control study within a prospective cohort of 1,590 singleton gestations referred for third-trimester evaluation (32-36 weeks of gestation)...
December 22, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28004170/uterine-artery-embolization-for-retained-products-of-conception-with-marked-vascularity-a-safe-and-efficient-first-line-treatment
#13
Paul Bazeries, Francine Paisant-Thouveny, Sultan Yahya, Antoine Bouvier, Cosmina Nedelcu, Francoise Boussion, Loic Sentilhes, Serge Willoteaux, Christophe Aubé
OBJECTIVE: To report our clinical practice regarding a case series of retained products of conception (RPOC) with marked vascularity (MV) managed with selective uterine artery embolization (UAE) as first-line treatment. METHODS: This was a monocentric, retrospective study of 31 consecutive cases of RPOC with MV diagnosed by Doppler ultrasound in the context of postpartum/postabortal bleeding. The primary outcome was the absence of rebleeding following embolization...
April 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/27925160/uterine-artery-doppler-measurements-during-first-and-second-trimesters-of-normal-pregnancy
#14
Solhild Stridsklev, Øyvind Salvesen, Kjell Å Salvesen, Sven M Carlsen, May A Husøy, Eszter Vanky
INTRODUCTION: The aim of this study was to construct a reference curve based on longitudinal Doppler blood flow measurements of the uterine artery during the first and second trimesters of normal pregnancy. MATERIAL AND METHODS: Healthy pregnant women (n = 124) between 18 and 38 years of age were included. The uterine artery pulsatility index (UtAPI) was measured with transvaginal ultrasound in the first trimester (gestational weeks 8-10 and 11-13) and with transabdominal ultrasound in the second trimester (gestational weeks 18 and 24)...
March 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/27914630/uterine-blood-flow-in-sheep-and-goats-during-the-peri-parturient-period-assessed-by-transrectal-doppler-sonography
#15
Mohammed Elmetwally, Heinrich Bollwein
The aim of the present study was to evaluate uterine blood flow (UBF) during the postpartum period in small ruminants. The study involved measures of UBF in 5 ewes and 5 goats during the first 4 weeks after parturition. Transrectal quantification of UBF was assessed by determining the diameter (DM), time averaged mean velocity (TAMEAN), blood flow volume (BFV), blood flow acceleration (ACCE) and pulsatility index (PI) in the uterine arteries ipsilateral to the previously gravid uterine horn(s) at Wk 20 of gestation and every 3days from the day of parturition (D 0) until Day 27 postpartum (D 27)...
January 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/27883242/sflt-1-plgf-for-early-onset-pre-eclampsia-prediction-steps-study-of-early-pre-eclampsia-in-spain
#16
A Perales, J L Delgado, M De La Calle, J A García-Hernández, A I Escudero, J M Campillos, M D Sarabia, B Laíz, M Duque, M Navarro, P Calmarza, M Hund, F V Álvarez
OBJECTIVES: A high ratio of soluble fms-like tyrosine kinase-1 (sFlt-1) to placental growth factor (PlGF) has been linked with pre-eclampsia (PE). We evaluated the sFlt-1/PlGF ratio as a predictive marker for early-onset PE in women at risk of PE. METHODS: This prospective, Spanish, multicenter study included pregnant women with PE risk factors (including: history of intrauterine growth restriction; PE; eclampsia; hemolysis, elevated liver enzymes and low platelet count syndrome; pre-gestational diabetes; and abnormal uterine artery Doppler ultrasound)...
November 24, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27862084/intra-and-inter-observer-reproducibility-and-generalizability-of-first-trimester-uterine-artery-pulsatility-index-by-transabdominal-and-transvaginal-ultrasound
#17
Laura Marchi, Eva Zwertbroek, Judith Snelder, Maaike Kloosterman, Caterina Maddalena Bilardo
OBJECTIVES: The primary aim of the study was to assess intra-observer and inter-observer reproducibility and generalizability (general reliability) of first trimester Doppler measurements of uterine arteries (UtA) performed both transabdominally (TA) and transvaginally (TV). Secondary aims were to investigate whether maternal BMI and acquisition modality (transabdominal or transvaginal) affect feasibility and reliability of UtA Doppler evaluation. METHODS: Singleton pregnancies between 11(+0) and 13(+6) weeks underwent TA and TV Doppler measurements of UtA prospectively, blindly and independently by Fetal Medicine Foundation-accredited operators...
December 2016: Prenatal Diagnosis
https://www.readbyqxmd.com/read/27824563/adaptive-spectral-envelope-estimation-for-doppler-ultrasound
#18
Aditi Kathpalia, Yucel Karabiyik, Sturla H Eik-Nes, Eva Tegnander, Ingvild Kinn Ekroll, Gabriel Kiss, Hans Torp
Estimation of accurate maximum velocities and spectral envelope in ultrasound Doppler blood flow spectrograms are both essential for clinical diagnostic purposes. However, obtaining accurate maximum velocity is not straightforward due to intrinsic spectral broadening and variance in the power spectrum estimate. The method proposed in this paper for maximum velocity point detection has been developed by modifying an existing method-signal noise slope intersection, incorporating in it steps from an altered version of another method called geometric method...
November 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/27739590/n-acetylcysteine-a-glutathione-precursor-reverts-vascular-dysfunction-and-endothelial-epigenetic-programming-in-intrauterine-growth-restricted-guinea-pigs
#19
Emilio A Herrera, Francisca Cifuentes-Zúñiga, Esteban Figueroa, Cristian Villanueva, Cherie Hernández, René Alegría, Viviana Arroyo-Jousse, Estefania Peñaloza, Marcelo Farías, Ricardo Uauy, Paola Casanello, Bernardo J Krause
KEY POINTS: Intrauterine growth restriction (IUGR) is associated with vascular dysfunction, oxidative stress and signs of endothelial epigenetic programming of the umbilical vessels. There is no evidence that this epigenetic programming is occurring on systemic fetal arteries. In IUGR guinea pigs we studied the functional and epigenetic programming of endothelial nitric oxide synthase (eNOS) (Nos3 gene) in umbilical and systemic fetal arteries, addressing the role of oxidative stress in this process by maternal treatment with N-acetylcysteine (NAC) during the second half of gestation...
February 15, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/27639435/-repeated-in-vitro-fertilization-failure-abnormalities-identified-in-the-diagnostic-assessment
#20
M Lambert, C Hocké, C Jimenez, S Frantz, A Papaxanthos, H Creux
OBJECTIVES: Investigate the proportion of abnormalities identified on the diagnostic assessment performed after at least two previous failed IVF attempts. Discuss the real benefit of this evaluation. METHODS: Retrospective descriptive study. Between January 2008 and January 2012, 205 couples with at least two consecutive failed IVF attempts had a diagnosis evaluation which consisted in couple's karyotypes; autoimmune and haemostasis biological check-up, pelvic ultrasound-Doppler and hysteroscopy for women...
October 2016: Gynécologie, Obstétrique & Fertilité
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