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Uterine artery doppler ultrasound

Emilio A Herrera, Francisca Cifuentes-Zúñiga, Esteban Figueroa, Cristian Villanueva, Cherie Hernández, René Alegría, Viviana Arroyo, Estefania Peñaloza, Marcelo Farías, Ricardo Uauy, Paola Casanello, Bernardo J Krause
In humans, intrauterine growth restriction (IUGR) is associated with vascular dysfunction, oxidative stress and signs of endothelial programming in umbilical vessels. We aimed to determine the effects of maternal antioxidant treatment with N-acetyl cysteine (NAC) on fetal endothelial function and eNOS programming in IUGR guinea pigs. IUGR was induced by implanting ameroid constrictors on uterine arteries of pregnant guinea pigs at mid gestation, receiving half of the sows NAC in the drinking water (from day 34 until term)...
October 14, 2016: Journal of Physiology
M Lambert, C Hocké, C Jimenez, S Frantz, A Papaxanthos, H Creux
OBJECTIVES: Investigate the proportion of abnormalities identified on the diagnostic assessment performed after at least two previous failed IVF attempts. Discuss the real benefit of this evaluation. METHODS: Retrospective descriptive study. Between January 2008 and January 2012, 205 couples with at least two consecutive failed IVF attempts had a diagnosis evaluation which consisted in couple's karyotypes; autoimmune and haemostasis biological check-up, pelvic ultrasound-Doppler and hysteroscopy for women...
September 14, 2016: Gynécologie, Obstétrique & Fertilité
Ozan Dogan, Ahmet Yildiz, Osman Temizkan, Cigdem Pulatoglu
OBJECTIVES: Blood flow to uterus and ovaries is demonstrated to be altered during mensturation. Studies has been published stating that blood flow differs also in ovulatory and anovulatory cycles. In this study, using color Doppler ultrasound, we aim to compare uterine, endometrial and ovarian blood flow during ovulatory and anovulatory cycles. MATERIAL AND METHODS: Women volunteers who are aged between 18-40 had no endocrinological problem and not recieving exogenous hormone therapy were included to study...
2016: Ginekologia Polska
Sudtawin Manthati, Busadee Pratumvinit, Ratchaneekorn Hanyongyuth, Suthipol Udompunthurak, Amprapha Phaophan, Tuangsit Wataganara
BACKGROUND: Data on first-trimester circulating soluble fms-like tyrosine kinase-1 (sFlt-1) and ischemic placental disease is limited and conflicting. This study aimed to study its physiology in relation to trophoblastic mass as the source of production. METHODS: Low-risk (representing normal placentation) women from 11 0/7 to 13 6/7 weeks' gestation were prospectively enrolled. Selective measurement of serum free sFlt-1 using a new automated assay from 100 eligible subjects was analyzed with gestational age, maternal weight, fetal crown-rump length (CRL), and mean uterine artery Doppler pulsatility index (PI)...
September 14, 2016: Journal of Maternal-fetal & Neonatal Medicine
Jacob Mørup Schlütter, Gry Johansen, Rikke Bek Helmig, Olav Bjørn Petersen
We report 2 cases of true uterine artery aneurysms diagnosed during pregnancy. Both cases presented with nonspecific symptoms such as urethral obstruction, minimal vaginal bleeding and lower abdominal pain in the 2nd trimester. Both aneurysms were diagnosed by color Doppler ultrasound. In the first case labor was induced at 37 + 4 weeks of gestation. However, due to sudden fetal distress and maternal abdominal pain, an emergency Caesarean section was performed during labor, and 3 liters of intra-peritoneal blood were encountered upon laparotomy, secondary to a ruptured uterine artery aneurysm...
September 13, 2016: Gynecologic and Obstetric Investigation
Alessandra Familiari, Carolina Scala, Maddalena Morlando, Amar Bhide, Asma Khalil, Basky Thilaganathan
INTRODUCTION: To evaluate the relative value of mid trimester fetal growth, uterine artery (UtA) Doppler indices and maternal demographics in prediction of stillbirth. MATERIAL AND METHODS: Retrospective cohort study; 23,894 singleton pregnancies routinely scanned between 19 and 24 weeks' gestation. Maternal characteristics included age, body mass index, ethnicity and medical history. Fetal biometry indices, birthweight and UtA pulsatility index (PI) values were converted to percentiles and multivariable logistic regression analysis was performed...
September 2, 2016: Acta Obstetricia et Gynecologica Scandinavica
P G Blanco, R Vercellini, A Rube, R Rodríguez, D O Arias, C Gobello
The aim of this study was to describe resistance index (RI) and systolic/diastolic ratio (S/D ratio) of uterine and umbilical arteries in an experimental model of abnormal pregnancy in felids. On days 30 to 35 (32 ± 2.9) after mating, 20 domestic short-hair pregnant queens were randomly assigned to one of the following treatment groups: a treated group (TG; n = 8), which received 10 mg/kg of aglepristone subcutaneously twice, 24 hours apart, and a control nontreated group (CG; n = 12). M-mode and Doppler ultrasonographic evaluations were performed at the initiation of the treatment (Day 0) and then every other day during 8 days...
August 4, 2016: Theriogenology
Isabela K R Agra, Maria L Brizot, Mariana Y Miyadahira, Mário H B Carvalho, Rossana P V Francisco, Marcelo Zugaib
OBJECTIVES: This study investigated the influence of vaginal progesterone on uterine circulation in asymptomatic twin gestations. STUDY DESIGN: This study was a secondary analysis of a randomized, double-blind, placebo-controlled trial of twin pregnancies exposed to vaginal progesterone or placebo. We included all trial participants who had undergone uterine artery pulsatility index evaluation at the time of randomization. During each ultrasound examination, the uterine artery pulsatility index was evaluated transabdominally...
October 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Alberto Borges Peixoto, Taciana Mara Rodrigues da Cunha Caldas, Tácito Augusto Godoy Silva, Mário Sérgio Silva Gomes Caetano, Wellington P Martins, Eduardo Felix Martins Santana, Edward Araujo Júnior
OBJECTIVES: The aim of the study was to investigate ultrasound and Doppler parameters in the third trimester of pregnancy as possible predictors of adverse perinatal outcome in unselected pregnancies. MATERIAL AND METHODS: We performed a retrospective cross-sectional study including unselected pregnant women be-tween 27 and 36 + 6 weeks of gestation. The following ultrasound and Doppler parameters were assessed: estimated fetal weight (EFW) [g], EFW percentile, placental maturity grade (Grannum classification), single vertical deepest pocket (SVDP) of amniotic fluid [cm], amniotic fluid index (AFI) [cm], mean uterine artery (UtA) pulsatility index (PI), umbilical artery (UA) PI, middle cerebral artery (MCA) PI, MCA peak systolic velocity (PSV) [cm/s], and cerebroplacental ratio (CPR)...
2016: Ginekologia Polska
Ilian Trayanov, Elena Dimitrakova
INTRODUCTION: According to the WHO, miscarriage is defined as "the loss of a pregnancy before the age of 20 weeks of gestation or fetal weight below 500 g". Only 50-60% of all conceptions fail to survive 20 weeks of gestation. It is estimated that about 75% of all unsuccessful conceptions are due to failed implantation and are not reported as spontaneous abortions. MATERIAL AND METHODS: We performed a prospective observational study at the Department of Obstetrics and Gynecology of the Medical University Plovdiv between October 2014 and September 2015...
2016: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
Renata Montes Dourado Abulé, Lisandra Stein Bernardes, Giovana Farina Doro, Seizo Miyadahira, Rossana Pulcinelli Vieira Francisco
OBJECTIVES: To evaluate placental volume and vascular indices in pregnancies with severe fetal growth restriction and determine their correlations to normal reference ranges and Doppler velocimetry results of uterine and umbilical arteries. METHODS: Twenty-seven fetuses with estimated weights below the 3rd percentile for gestational age were evaluated. Placental volume and vascular indices, including vascularization, flow, and vascularization flow indices, were measured by three-dimensional ultrasound using a rotational technique and compared to a previously described nomogram...
July 2016: Clinics
Charlotte Oyston, Joanna L Stanley, Mark H Oliver, Frank H Bloomfield, Philip N Baker
Intrauterine growth restriction (IUGR) causes short- and long-term morbidity. Reduced placental perfusion is an important pathogenic component of IUGR; substances that enhance vasodilation in the uterine circulation, such as sildenafil citrate (sildenafil), may improve placental blood flow and fetal growth. This study aimed to examine the effects of sildenafil in the growth-restricted ovine fetus. Ewes carrying singleton pregnancies underwent insertion of vascular catheters, and then, they were randomized to receive uterine artery embolization (IUGR) or to a control group...
September 2016: Hypertension
Manisha Kumar, Shalini Singh, Karuna Sharma, Ritu Singh, V Ravi, J Bhattacharya
AIMS AND OBJECTIVES: To evaluate the predictive value of first trimester biomarkers and ultrasound in determining adverse fetal outcomes in a low risk Asian population. MATERIAL AND METHOD: All low risk, singleton pregnancies between 11 and 14 weeks gestation underwent ultrasound with uterine artery Doppler along with PAPP-A and free β-hCG estimation, and were followed till delivery to observe the outcome. The adverse fetal outcomes detected were structural anomaly, aneuploidy, intrauterine growth restriction, preterm birth and stillbirth (SB)...
August 10, 2016: Journal of Maternal-fetal & Neonatal Medicine
Aditi Kathpalia, Yucel Karabiyik, Sturla Eik-Nes, Eva Tegnander, Ingvild Ekroll, Gabriel Kiss, Hans Torp
Estimation of accurate maximum velocities and spectral envelope in ultrasound Doppler blood flow spectrograms are both essential for clinical diagnostic purposes. However, obtaining accurate maximum velocity is not straightforward due to intrinsic spectral broadening and variance in the power spectrum estimate. The method proposed in this work for maximum velocity point detection has been developed by modifying an existing method - Signal Noise Slope Intersection (SNSI), incorporating in it steps from an altered version of another method called Geometric Method (GM)...
July 7, 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Narayanan Lalitha, Panicker Seetha, R Shanmugasundaram, G Rajendiran
BACKGROUND: Uterine AV malformation is a rare cause of torrential post-abortal hemorrhage, which can present with varying grades of severity. Diagnosis requires a high degree of suspicion and is done with ultrasound and Doppler. CASE SERIES: In our institution, during the period 2008-2013, five cases of symptomatic uterine AVMs have been reported. All of them were in the reproductive age group (22-36 years), presenting with a history of miscarriage or termination of pregnancy for which curettage was done...
August 2016: Journal of Obstetrics and Gynaecology of India
Terri A Levine, Fiona A Alderdice, Ruth E Grunau, Fionnuala M McAuliffe
Maternal prenatal stress is associated with preterm birth, intrauterine growth restriction, and developmental delay. However, the impact of prenatal stress on hemodynamics during pregnancy remains unclear. This systematic review was conducted in order to assess the quality of the evidence available to date regarding the relationship between prenatal stress and maternal-fetal hemodynamics. The PubMed/Medline, EMBASE, PsycINFO, Maternity and Infant Care, Trip, Cochrane Library, and CINAHL databases were searched using the search terms pregnancy; stress; fetus; blood; Doppler; ultrasound...
October 2016: Archives of Women's Mental Health
R A Hawkes, A J Patterson, A N Priest, G Harrison, S Hunter, J Pinney, P Set, N Hilliard, M J Graves, G C S Smith, D J Lomas
OBJECTIVE: The aim of this work was to evaluate whether the uterine arteries (UtA) could be identified and their flow profiles measured during a fetal MRI examination. A comparison was performed against same day sonographic Doppler assessment. METHODS: 35 normal, healthy, singleton pregnancies at 28-32 weeks gestation underwent routine Doppler examination, followed by MRI examination. The resistivity index (RI) and pulsatility index (PI) of the left and right UtA were measured using phase contrast MRI...
July 2016: Placenta
Sebastian Kwiatkowski, Ewa Kwiatkowska, Rafał Rzepka, Barbara Dołegowska, Andrzej Torbe, Agata Bartosik-Sławińska
OBJECTIVE: The shared pathogenesis of placental ischemia entitles us to create a single treatment model. We attempted to develop a unified method for monitoring ischemic placental syndrome patients using Doppler ultrasound of the uterine and umbilical arteries and disordered angiogenesis markers sFlt-1 and PlGF. MATERIAL AND METHODS: 182 pregnant women suffering from the ischemic placental syndrome were divided into four groups depending on the severity of their lesions revealed in the Doppler ultrasound examination and weeks of pregnancy...
June 17, 2016: Hypertension in Pregnancy
Franz Bahlmann, Ammar Al Naimi
PURPOSE: The aim of this study is to assess the value of the angiogenic factors for diagnosing preeclampsia and predicting the severity of manifestation. A secondary aim is assessing the combination of the uterine artery Doppler with the angiogenic factors for improving the diagnostic power. METHODS: This is a prospective single center study in a tertiary referral hospital. This study includes 728 individual patients. Inclusion criteria were singleton pregnancies, a referral to the hospital with suspicion of preeclampsia and any one or combination of the following symptoms: headache, upper abdominal pain, edema, and hypertension...
June 2, 2016: Archives of Gynecology and Obstetrics
Tianjie Zhang, Yaqiong He, Yuan Wang, Qingling Zhu, Jing Yang, Xiaoming Zhao, Yun Sun
OBJECTIVE: To investigate the value of ultrasound for the assessment of endometrial receptivity during in vitro fertilization (IVF) and embryo transfer (ET). MATERIALS AND METHODS: Only those patients in their first IVF cycle, followed a standard long gonadotropin releasing hormone (GnRH) agonist long ovarian stimulation regimen, and had 2 highest scoring embryos transferred on day 3 were included in the study. A 3D ultrasound examination was performed on the day of human chorionic gonadotropin (hCG) injection to determine endometrial thickness, endometrial pattern, peak systolic velocity (PSV), end diastolic velocity (EDV), pulsatility index (PI) and resistance index (RI) of endometrial spiral arteries, endometrial volume, vascularization index (VI), flow index (FI) and vasculariztion flow index (VFI) of endometrial and subendometrial region...
August 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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