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https://www.readbyqxmd.com/read/29783094/the-relation-of-parent-alcohol-disorder-to-young-adult-drinking-outcomes-mediated-by-parenting-effects-of-developmentally-limited-versus-persistent-parent-alcohol-disorder
#1
Ariel Sternberg, Danielle Pandika, Kit K Elam, Laurie Chassin
BACKGROUND: Parent alcohol use disorder (AUD) is a well-established risk factor for the development of offspring AUD and is associated with poor parenting. However, few studies have examined heterogeneity in trajectories of parental AUD and its influence on adolescent offspring drinking, and no studies to date have considered the differential risk to offspring conferred by parental AUDs that are limited to early adulthood. Specifically, AUDs limited to the period of emerging adulthood may confer less risk to a child's environment as recovery following emerging adulthood coincides with the typical ages of entry into the parenting role...
April 25, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29782482/trauma-patients-are-safe-to-fly-72-hours-after-tube-thoracostomy-removal
#2
David Zonies, Joel Elterman, Christopher Burns, Vincent Paul, John Oh, Jeremy Cannon
BACKGROUND: Current recommendations for safe air travel following traumatic pneumothorax are 2-3 weeks after radiographic resolution. These recommendations are based on several small observational studies and expert consensus which cite a theoretical risk of recurrence and hypoxia due to decreased oxygen tension at altitude. We sought to systematically study the timing of chest drain removal after traumatic pneumothorax and risk of recurrence in relation to air travel. METHODS: A retrospective cohort study of consecutively admitted patients who sustained a traumatic chest injury treated with tube thoracostomy over a 5-year period was undertaken...
May 18, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29781365/mental-health-interventions-among-older-adults-a-systematic-review
#3
Janni Niclasen, Lisbeth Lund, Carsten Obel, Lars Larsen
BACKGROUND: The aim of the present study was to conduct a systematic review to identify documented mental health promotion interventions developed and tested among population-based older adults. METHODS: A systematic review based on PRISMA guidelines. The literature was searched in PsycINFO and PubMed between June and September 2016. The Effective Public Health Practice Project tool was used to assess the quality of the included study. RESULTS: In total 53 randomized controlled trial studies qualified for the systematic review...
May 1, 2018: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/29781293/mindfulness-based-group-therapy-impact-on-psychiatrically-hospitalized-adolescents
#4
Deanna P Sams, Elizabeth D Handley, Linda J Alpert-Gillis
The practice of mindfulness has long been incorporated into psychotherapy. Research on the therapeutic benefits of mindfulness exists within adult populations, and emerging empirical evidence demonstrates the benefit of such practices in the treatment of adolescents in both clinical and non-clinical settings. However, there are extremely limited data on the practice of mindfulness with adolescents in a psychiatric hospital. The iMatter ( Improve Mindful ATTention, Enhance Relaxation) group is a manualized program developed to provide adolescents on a short-term psychiatric inpatient unit with an opportunity to learn and practice relaxation strategies, mindfulness exercises, and simple yoga poses...
May 1, 2018: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/29780813/loss-of-heterogeneity-quiescence-and-differentiation-in-muscle-stem-cells
#5
REVIEW
Haser Hasan Sutcu, Miria Ricchetti
Skeletal muscle stem cells in the adult display heterogeneity that has been functionally linked to their behavior, self-renewal capacity, and resistance to stress in hostile environments. Behavioral heterogeneity emerges also during developmental myogenesis. Muscle stem cell diversity may be functionally linked to the changing needs of skeletal muscle regeneration. Intriguingly, dramatic reduction of stem cell diversity, the "clonal drift", that implies loss of stem cells and related expansion of clonally related stem cells has been reported for tissue replacement in several adult tissues and suggested in the zebrafish embryo...
2018: Stem Cell Investigation
https://www.readbyqxmd.com/read/29780586/asthma-related-health-services-and-asthma-control-among-women-in-puerto-rico
#6
María Calixta Ortiz-Rivera
Objectives: This study evaluates social, behavioral, and environmental determinants to differentiate between active and inactive asthma and how predisposing, enabling, and need factors elucidate asthma-related health services and asthma control among women in Puerto Rico. Methods: This study analyzed secondary cross-sectional data from a subsample of 625 adult females who participated in the Asthma Call Back Survey in Puerto Rico. Logistic and multinomial regression analyses were conducted to examine associations between explanatory variables and asthma outcomes...
2018: SAGE Open Medicine
https://www.readbyqxmd.com/read/29779793/older-adults-response-to-analgesic-adverse-drug-reactions-a-pilot-study
#7
Deborah Dillon McDonald, Sarah Coughlin, Candy Jin
Older adults who take analgesics for chronic pain are at increased risk for adverse drug events (ADEs). The purpose of this descriptive pilot survey was to examine how older adults self-identify analgesic ADEs, and actions they take in response to analgesic ADEs. Twenty-two community dwelling older adults with chronic pain who reported an analgesic ADE associated with their chronic pain management were interviewed and asked to describe their analgesic related ADE. Written responses were content analyzed. Nineteen opioids were reported by 15, 11 NSAIDs were reported by 8, and acetaminophen was reported by 2 older adults as associated with an ADE...
May 17, 2018: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://www.readbyqxmd.com/read/29779737/neurodevelopmental-perspectives-on-dance-learning-insights-from-early-adolescence-and-young-adulthood
#8
Dilini K Sumanapala, Jon Walbrin, Louise P Kirsch, Emily S Cross
Studies investigating human motor learning and movement perception have shown that similar sensorimotor brain regions are engaged when we observe or perform action sequences. However, the way these networks enable translation of complex observed actions into motor commands-such as in the context of dance-remains poorly understood. Emerging evidence suggests that the ability to encode specific visuospatial and kinematic movement properties encountered via different routes of sensorimotor experience may be an integral component of action learning throughout development...
2018: Progress in Brain Research
https://www.readbyqxmd.com/read/29779504/association-of-dietary-patterns-of-american-adults-with-bone-mineral-density-and-fracture
#9
Mohsen Mazidi, Andre Pascal Kengne, Hassan Vatanparast
OBJECTIVE: In a representative sample of US adults, we investigated the associations of nutrient patterns (NP) with bone mineral density (BMD) and fractures. DESIGN: Cross-sectional. SETTING: US community-based National Health and Nutrition Examination Survey (NHANES). SUBJECTS: Participants with measured data on dietary intake and BMD from 2005 to 2010 were included. Principal components analysis was used to identify NP...
May 21, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29778808/maternal-treatment-with-a-placental-targeted-antioxidant-mitoq-impacts-offspring-cardiovascular-function-in-a-rat-model-of-prenatal-hypoxia
#10
Mais M Aljunaidy, Jude S Morton, Raven Kirschenman, Tom Phillips, C Patrick Case, Christy-Lynn M Cooke, Sandra T Davidge
Intrauterine growth restriction, a common consequence of prenatal hypoxia, is a leading cause of fetal morbidity and mortality with a significant impact on population health. Hypoxia may increase placental oxidative stress and lead to an abnormal release of placental-derived factors, which are emerging as potential contributors to developmental programming. Nanoparticle-linked drugs are emerging as a novel method to deliver therapeutics targeted to the placenta and avoid risking direct exposure to the fetus...
May 17, 2018: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/29778801/injury-and-stress-responses-of-adult-neural-crest-derived-cells
#11
REVIEW
Vadims Parfejevs, Ana T Antunes, Lukas Sommer
Multipotent neural crest cells can self-renew and give rise to a plethora of neural and non-neural cell types in the vertebrate embryo. Intriguingly, cells reminiscent of such neural crest stem cells (NCSCs) have also been isolated from various postnatal and adult neural crest (NC)-derived structures. However, it has been debated whether NCSC-like cells in the adult correspond to 'in vitro artefacts' emerging upon isolation or fulfil a physiological role in vivo. Here, we discuss recent findings indicating that in different adult NC derivatives, injury or stress responses induce a NCSC-like state, presumably by reprogramming of differentiated cells such as Schwann cells...
May 17, 2018: Developmental Biology
https://www.readbyqxmd.com/read/29778539/expressional-and-functional-comparisons-of-two-general-odorant-binding-proteins-in-agrotis-ipsilon
#12
Guang-Zhen Huang, Jing-Tao Liu, Jing-Jiang Zhou, Qian Wang, Jian-Zhen Dong, Yong-Jun Zhang, Xian-Chun Li, Jing Li, Shao-Hua Gu
Insect general odorant binding proteins (GOBPs) have been long thought to bind and transport host plant volatiles to the olfactory receptors on the dendrite membrane of the olfactory neurons. Recent studies indicate that they can also bind female sex pheromones. In present study, two GOBP genes, AipsGOBP1 and AipsGOBP2 were cloned from the adult antennae of Agrotis ipsilon. Tissue expression profiles indicated that both of them are antennae-specific and more abundant in the female antennae than in the male antennae...
May 17, 2018: Insect Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29778489/trends-in-non-medical-prescription-opioids-and-heroin-co-use-among-adults-2003-2014
#13
Sasha Mital, Michael Windle, Hannah L F Cooper, Natalie D Crawford
BACKGROUND: Patterns in non-medical prescription opioid (NMPO) and heroin use have recently shifted, with evidence that NMPO-only users transition to NMPO and heroin co-use. Co-use is associated with increased risk of morbidity and overdose, highlighting the need for further investigation. This study aims to quantify, describe, and explore trends in co-use. METHODS: Using data from the 2003-2014 National Surveys on Drug Use and Health, we compared co-use to NMPO- and heroin-only use across demographic, substance use and mental health characteristics with chi-squared tests...
May 16, 2018: Addictive Behaviors
https://www.readbyqxmd.com/read/29778034/early-discharge-of-patients-with-pulmonary-embolism-in-daily-clinical-practice-a-prospective-observational-study-comparing-clinical-gestalt-and-clinical-rules
#14
Simone Vanni, Cecilia Becattini, Peiman Nazerian, Carlo Bova, Valerio Teodoro Stefanone, Ludovica Anna Cimini, Gabriele Viviani, Cosimo Caviglioli, Michela Sanna, Giuseppe Pepe, Stefano Grifoni
OBJECTIVES: To estimate the efficiency and safety of clinicians' gestalt in the identification of patients with pulmonary embolism (PE) candidates for early discharge and to compare the efficiency and safety of clinical gestalt with that of the Pulmonary Embolism Severity Index (PESI), the simplified PESI (sPESI) and the Hestia criteria (HC). METHODS: Consecutive adult patients presenting to the emergency department of four Italian hospitals with confirmed diagnosis of PE were included...
May 8, 2018: Thrombosis Research
https://www.readbyqxmd.com/read/29778009/exploring-opioid-use-disorder-its-impact-and-treatment-among-individuals-experiencing-homelessness-as-part-of-a-family
#15
Avik Chatterjee, Eun Jin Yu, Lindsay Tishberg
BACKGROUND: Opioid Use Disorder (OUD) causes significant morbidity and mortality among people experiencing homelessness. We aimed to explore the unique way in which OUD impacts individuals experiencing homelessness as part of a family. METHODS: We conducted semi-structured interviews with adults experiencing OUD staying in Boston-area family shelters along with dependent children. We used Borkan's Immersion-Crystallization method to uncover themes from interview transcripts...
May 12, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29777350/the-american-association-for-the-surgery-of-trauma-emergency-general-surgery-anatomic-severity-scoring-system-as-a-predictor-of-cost-in-appendicitis
#16
Eric J Finnesgard, Matthew C Hernandez, Johnathon M Aho, Martin D Zielinski
BACKGROUND: The World Society for Emergency Surgery determined that for appendicitis managed with appendectomy, there is a paucity of evidence evaluating costs with respect to disease severity. The American Association for the Surgery of Trauma (AAST) disease severity grading system is valid and generalizable for appendicitis. We aimed to evaluate hospitalization costs incurred by patients with increasing disease severity as defined by the AAST. We hypothesized that increasing disease severity would be associated with greater cost...
May 17, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29777111/knockdown-of-rna-interference-pathway-genes-impacts-the-fitness-of-western-corn-rootworm
#17
Courtney Davis-Vogel, Angel Ortiz, Lisa Procyk, Jonathan Robeson, Adane Kassa, Yiwei Wang, Emily Huang, Carl Walker, Amit Sethi, Mark E Nelson, Dipali G Sashital
Western corn rootworm (Diabrotica virgifera virgifera) is a serious agricultural pest known for its high adaptability to various management strategies, giving rise to a continual need for new control options. Transgenic maize expressing insecticidal RNAs represents a novel mode of action for rootworm management that is dependent on the RNA interference (RNAi) pathways of the insect for efficacy. Preliminary evidence suggests that western corn rootworm could develop broad resistance to all insecticidal RNAs through changes in RNAi pathway genes; however, the likelihood of field-evolved resistance occurring through this mechanism remains unclear...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29776997/turning-workers-into-false-queens-the-role-of-exogenous-pheromones-in-regulating-reproduction-in-worker-honey-bees
#18
Abdullahi A Yusuf, Robin M Crewe, Christian W W Pirk
One of the responses that honey bee workers can make in the event of queen loss is to develop into false queens. False queens are workers that exhibit both behavioural and physiological traits similar to those of a true queen. However, the presence of more than one false queen in a colony distorts the established hierarchies. As transformation into a false queen occurs after emergence as an adult, we tested the effect of worker mobile pheromone carriers (PCs) treated with exogenously supplied pheromones on their nestmates...
May 18, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29776828/septic-acute-kidney-injury-patients-in-emergency-department-the-risk-factors-and-its-correlation-to-serum-lactate
#19
Yin-Chou Hsu, Chih-Wei Hsu
BACKGROUND: Acute kidney injury (AKI) is a common complication in septic patients, imposing a heavy burden of illness in terms of morbidity and mortality. Serum lactate is a widely used marker predicting the severity of sepsis. A paucity of research has investigated septic AKI in emergency departments (EDs) and its correlation with initial serum lactate level. This study aimed at identifying risk factors for septic AKI and clarifying the link between initial serum lactate level and septic AKI in ED patients...
May 15, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29776800/risk-of-emergency-hospital-admission-in-children-associated-with-mental-disorders-and-alcohol-misuse-in-the-household-an-electronic-birth-cohort-study
#20
Shantini Paranjothy, Annette Evans, Amrita Bandyopadhyay, David Fone, Behnaz Schofield, Ann John, Mark A Bellis, Ronan A Lyons, Daniel Farewell, Sara Jayne Long
BACKGROUND: Mental disorders and alcohol misuse are common in families but their effects on the physical health of children are not known. We investigated the risk of emergency hospital admissions during childhood associated with living with an adult who has a mental health disorder, or who had an alcohol-related hospital admission. METHODS: We did this cohort study in a total population electronic child cohort in Wales, UK, which includes all children who live in Wales or with a mother who is resident in Wales...
May 15, 2018: Lancet. Public Health
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