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https://www.readbyqxmd.com/read/28641248/method-for-simulating-dose-reduction-in-digital-breast-tomosynthesis
#1
Lucas R Borges, Igor Guerrero, Predrag R Bakic, Alessandro Foi, Andrew D A Maidment, Marcelo A C Vieira
This work proposes a new method of simulating dose reduction in digital breast tomosynthesis (DBT), starting from a clinical image acquired with a standard radiation dose. It considers both signal-dependent quantum and signal-independent electronic noise. Furthermore, the method accounts for pixel crosstalk, which causes the noise to be frequency-dependent, thus increasing the simulation accuracy. For an objective assessment, simulated and real images were compared in terms of noise standard deviation, signal-to-noise ratio (SNR) and normalized noise power spectrum (NNPS)...
June 15, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28639832/comparing-diagnostic-performance-of-digital-breast-tomosynthesis-and-full-field-digital-mammography-in-a-hybrid-screening-environment
#2
Catherine S Giess, Sarvenaz Pourjabbar, Ivan K Ip, Ronilda Lacson, Emily Alper, Ramin Khorasani
OBJECTIVE: The purpose of this study is to compare the diagnostic performance of screening digital breast tomosynthesis (DBT) to that of full-field digital mammography (FFDM) in a mixed DBT and FFDM imaging environment. MATERIALS AND METHODS: This retrospective observational study consisted of all female patients undergoing screening DBT or FFDM at an academic medical center and outpatient imaging facility between October 2012 and May 2015. Patient demographics and personal history of breast cancer were collected from the electronic medical record...
June 22, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28637970/impact-of-door-to-balloon-time-in-patients-with-st-elevation-myocardial-infarction-who-arrived-by-self-transport%C3%A3-acute-myocardial-infarction-kyoto-multi-center-risk-study-group
#3
Naotoshi Kodama, Takeshi Nakamura, Kenji Yanishi, Naohiko Nakanishi, Kan Zen, Tetsuhiro Yamano, Hirokazu Shiraishi, Takeshi Shirayama, Jun Shiraishi, Takahisa Sawada, Yoshio Kohno, Makoto Kitamura, Keizo Furukawa, Satoaki Matoba
BACKGROUND: Patients with ST-elevation myocardial infarction (STEMI) who arrive at a hospital via self-transport reportedly have a delayed door-to-balloon time (DBT). However, the clinical impacts of delayed DBT on in-hospital mortality among such patients are not well known.Methods and Results:In total, 1,172 STEMI patients who underwent primary percutaneous coronary intervention between January 2009 and December 2013 from the Acute Myocardial Infarction (AMI) Kyoto Registry were analyzed...
June 20, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28629811/tbt-and-its-metabolites-in-sediments-survey-at-a-german-coastal-site-and-the-central-baltic-sea
#4
Marion Abraham, Lina Westphal, Ines Hand, Astrid Lerz, Jenny Jeschek, Dennis Bunke, Thomas Leipe, Detlef Schulz-Bull
Since the 1950s the organotin compound tributyltin (TBT) was intensively used in antifouling paints for marine vessels and it became of concern for the marine environment. Herein, we report on a study from 2015 on TBT and its metabolites monobutyltin (MBT) and dibutyltin (DBT) in sediments from the central Baltic Sea and a Baltic Sea coastal site with strong harbor activities (Warnemünde). Sublayers from a sediment core from the Arkona Basin were analyzed to investigate the long term organotin pressure for the Baltic Sea...
June 16, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28607364/desulfurization-of-model-oil-by-selective-adsorption-over-porous-boron-nitride-fibers-with-tailored-microstructures
#5
Zhiyi Yan, Jing Lin, Xiaohai Yuan, Tao Song, Chao Yu, Zhenya Liu, Xin He, Jianli Liang, Chengchun Tang, Yang Huang
We report on the controllable synthesis of porous BN microfibers and explore their applications as adsorbent for removing dibenzothiophene (DBT) in model oil. The growth evolution of porous BN microfibers has been carefully investigated by correlating their structural characteristics with their synthesis conditions. The as-prepared BN microfibers exhibit very high adsorption capacity for DBT (86 mg S g(-1) according to the Langmuir isotherm model), showing excellent adsorptive desulfurization performance...
June 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28598261/neurotoxicity-of-alkylated-polycyclic-aromatic-compounds-in-human-neuroblastoma-cells
#6
Sailendra Nath Sarma, Jules M Blais, Hing Man Chan
Polycyclic aromatic compounds (PAC) are ubiquitous environmental pollutants originating from incomplete combustion processes. While the toxicity of parent PAC such as benzo[a]pyrene (BaP) is well characterized, effects of other alkyl-PAC dibenzothiophene (DBT) and retene (Ret) are not well established. The aim of this study was to examine the underlying relative neurotoxic mechanisms attributed to BaP (parent PAH), DBT and Ret (alkyl-PACs) using human neuroblastoma SK-N-SH cells. The lethal concentrations (LC10 and LC20) were found at approximately 10 µM and 40 µM, respectively after 24-h exposure of SK-N-SH cells...
June 9, 2017: Journal of Toxicology and Environmental Health. Part A
https://www.readbyqxmd.com/read/28581563/a-specific-environment-sensitive-near-infrared-fluorescent-turn-on-probe-for-synergistic-enhancement-of-anticancer-activity-of-a-chemo-drug
#7
Jun Li, Zhipeng Zhu, Shaoqin Rong, Heran Li, Yuenan Guo, Qiang Xue, Dan Ding
Chemotherapy is one of the main categories of clinical cancer treatment. One of the hindrances of a popularly used chemo-drug doxorubicin (DOX) is that some types of cancer cells are or become insensitive/resistant to DOX. In this work, we report a near-infrared (NIR) fluorescent turn-on probe DBT-2EEGYLFFVFER by conjugation of an environment-sensitive fluorophore DBT with human epidermal growth factor receptor 2 (HER2) specific binding peptides. Besides the NIR fluorescence turn-on signature, DBT-2EEGYLFFVFER also has activatable capability of reactive oxygen species (ROS) generation...
June 5, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/28577590/dialectical-behavior-therapy-group-skills-training-for-bipolar-disorder
#8
Lori Eisner, David Eddie, Rebecca Harley, Michelle Jacobo, Andrew A Nierenberg, Thilo Deckersbach
There is growing evidence that the capacity for emotion regulation is compromised in individuals with bipolar disorder. Dialectical behavior therapy (DBT), an empirically supported treatment that specifically targets emotion dysregulation, may be an effective adjunct treatment for improving emotion regulation and residual mood symptoms in patients with bipolar disorder. In this open, proof-of-concept pilot study, 37 participants engaged in a 12-week DBT group skills training program, learning mindfulness, emotion regulation, and distress tolerance skills...
July 2017: Behavior Therapy
https://www.readbyqxmd.com/read/28573453/diurnal-thermoregulatory-responses-in-pregnant-yankasa-ewes-to-the-dry-season-in-a-tropical-savannah
#9
Lukuman Surakat Yaqub, Joseph Olusegun Ayo, Muhammad Umar Kawu, Peter Ibrahim Rekwot
The study investigated concomitant effect of gestation and high ambient temperature under a tropical environment on rectal temperature (RT), respiratory rate (RR) and heart rate (HR) responses in Yankasa ewes. Twenty Yankasa ewes, consisting of ten pregnant and ten non-pregnant ewes, were used for the study. Ewes were synchronised and bred, such that each gestation phase coincided with different periods of the dry-seasons, early-gestation (cold/harmattan), mid-gestation (peak hot-dry) and late-gestation (late hot-dry)...
June 1, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28569999/second-generation-stationary-digital-breast-tomosynthesis-system-with-faster-scan-time-and-wider-angular-span
#10
Jabari Calliste, Gongting Wu, Philip E Laganis, Derrek Spronk, Houman Jafari, Kyle Olson, Bo Gao, Yueh Z Lee, Otto Zhou, Jianping Lu
PURPOSE: To characterize a new generation stationary digital breast tomosynthesis system with higher tube flux and increased angular span over a first generation system. METHODS: The linear CNT x-ray source was designed, built and evaluated to determine its performance parameters. The second generation system was then constructed using the CNT x-ray source and a Hologic gantry. Upon construction, test objects and phantoms were used to characterize system resolution as measured by the modulation transfer function (MTF), and artifact spread function (ASF)...
June 1, 2017: Medical Physics
https://www.readbyqxmd.com/read/28559765/value-of-digital-breast-tomosynthesis-versus-additional-views-for-the-assessment-of-screen-detected-abnormalities-a-first-analysis
#11
Sylvia Heywang-Köbrunner, Alexander Jaensch, Astrid Hacker, Sabina Wulz-Horber, Thomas Mertelmeier, Dieter Hölzel
BACKGROUND: The purpose of this study was to countercheck the equivalence of single-view digital breast tomosynthesis (DBT) or DBT with additional views (DBT+AV) compared to traditional standard assessment by additional views (AV) in patients with a screen-detected abnormality. PATIENTS AND METHODS: Patients with a screen-detected abnormality were consecutively invited to obtain 1 single-view wide-angle DBT in addition to the indicated AV. The study was approved by the local ethics committee and by the Federal Office for Radiation Protection...
May 2017: Breast Care
https://www.readbyqxmd.com/read/28545758/the-role-of-affect-management-for-hiv-risk-reduction-for-youth-in-alternative-schools
#12
Larry K Brown, Laura Whiteley, Christopher D Houck, Lacey K Craker, Ashley Lowery, Nancy Beausoleil, Geri Donenberg
OBJECTIVE: Adolescents in alternative schools for behavioral and emotional problems have an earlier sexual onset and higher rates of sexual risk than their peers. They also often have difficulty managing strong emotions, which can impair sexual decision making. Human immunodeficiency virus (HIV) prevention programs for these adolescents may be most effective if skills for coping with strong emotions during sexual situations are included. METHOD: This article reports the 6-month outcomes of a three-arm randomized controlled trial comparing an HIV prevention intervention with affect management (AM) to a standard, skills-based HIV prevention intervention (SB), and a general health promotion intervention (HP)...
June 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28543761/experimental-characterization-of-a-direct-conversion-amorphous-selenium-detector-with-thicker-conversion-layer-for-dual-energy-contrast-enhanced-breast-imaging
#13
David A Scadutom, Olivier Tousignant, Wei Zhao
PURPOSE: Dual-energy contrast-enhanced imaging is being investigated as a tool to identify and localize angiogenesis in the breast, a possible indicator of malignant tumors. This imaging technique requires that x-ray images are acquired at energies above the k-shell binding energy of an appropriate radiocontrast agent. Iodinated contrast agents are commonly used for vascular imaging, and require x-ray energies greater than 33 keV. Conventional direct conversion amorphous selenium (a-Se) flat panel imagers for digital mammography show suboptimal absorption efficiencies at these higher energies...
May 21, 2017: Medical Physics
https://www.readbyqxmd.com/read/28540564/digital-breast-tomosynthesis-dbt-recommendations-from-the-italian-college-of-breast-radiologists-icbr-by-the-italian-society-of-medical-radiology-sirm-and-the-italian-group-for-mammography-screening-gisma
#14
Daniela Bernardi, Paolo Belli, Eva Benelli, Beniamino Brancato, Lauro Bucchi, Massimo Calabrese, Luca A Carbonaro, Francesca Caumo, Beatrice Cavallo-Marincola, Paola Clauser, Chiara Fedato, Alfonso Frigerio, Vania Galli, Livia Giordano, Paolo Giorgi Rossi, Paola Golinelli, Doralba Morrone, Giovanna Mariscotti, Laura Martincich, Stefania Montemezzi, Carlo Naldoni, Adriana Paduos, Pietro Panizza, Federica Pediconi, Fiammetta Querci, Antonio Rizzo, Gianni Saguatti, Alberto Tagliafico, Rubina M Trimboli, Marco Zappa, Chiara Zuiani, Francesco Sardanelli
This position paper, issued by ICBR/SIRM and GISMa, summarizes the evidence on DBT and provides recommendations for its use. In the screening setting, DBT in adjunct to digital mammography (DM) increased detection rate by 0.5-2.7‰ and decreased false positives by 0.8-3.6% compared to DM alone in observational and double-testing experimental studies. The reduction in recall rate could be less prominent in those screening programs which already have low recall rates with DM. The increase in radiation exposure associated with DM/DBT protocols has been solved by the introduction of synthetic mammograms (sDM) reconstructed from DBT datasets...
May 25, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28535623/-the-breast-cancer-diagnosis-accuracy-of-the-digital-breast-tomosynthesis-technique
#15
H W Zhang, J T Li, M H Lü, L Qin, L F Li, S D Cui, H Liu
Objective: To explore the Digital breast tomosynthesis technique (DBT) in breast cancer diagnosis accuracy. Methods: Choose 263 cases of patients with breast lesions, using DBT combined FFDM (Full field digital mammography) independent FFDM, evaluate the diagnostic accuracy of breast cancer. Results: The ROC curve area (AUC) of two kinds of breast cancer diagnosis methods (DBT combined FFDM and independent FFDM) were 0.954±0.014 and 0.907±0.019, with significant difference (P=0.000 3). In premenopausal patients and breast density ACR3-4 cases, DBT combined FFDM diagnosis accuracy is higher than FFDM alone group, with significant difference (P<0...
May 16, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28525881/preparation-of-mesoporous-cs-pom-mof-199-mcm-41-under-two-different-synthetic-methods-for-a-highly-oxidesulfurization-of-dibenzothiophene
#16
Si-Wen Li, Jia-Rong Li, Qi-Ping Jin, Zhi Yang, Rong-Lan Zhang, Rui-Min Gao, Jian-She Zhao
Two different synthetic methods, the direct method and the substitution method, were used to synthesize the Cs-POM@MOF-199@MCM-41 (Cs-PMM), in which the modified heteropolyacid with cesium salt has been encapsulated into the pores with the mixture of MOF and MCM-41. The structural properties of the as-prepared catalysts were characterized using various analytical techniques: powder X-ray diffraction, FT-IR, SEM, TEM, XPS and BET, confirming that the Cs-POM active species retained its Keggin structure after immobilization...
April 15, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28516226/benefit-of-adding-digital-breast-tomosynthesis-to-digital-mammography-for-breast-cancer-screening-focused-on-cancer-characteristics-a-meta-analysis
#17
REVIEW
Seong Jong Yun, Chang-Woo Ryu, Sun Jung Rhee, Jung Kyu Ryu, Ji Young Oh
PURPOSE: We evaluated the benefit of adding digital breast tomosynthesis (DBT) to full-field digital mammography (FFDM) compared to FFDM alone for breast cancer detection, focusing on cancer characteristics. METHODS: We searched electronic databases and relevant references for published studies comparing DBT plus FFDM to FFDM alone for breast cancer screening. Pooled risk ratios (RRs) for various pathologic findings were determined using random effects models. RESULTS: Eleven eligible studies were included...
May 18, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28480806/mechanisms-of-change-in-dialectical-behaviour-therapy-and-cognitive-behaviour-therapy-for-borderline-personality-disorder-a-critical-review-of-the-literature
#18
Susie Rudge, Janet Denise Feigenbaum, Peter Fonagy
BACKGROUND: Little is known about the "active ingredients" of psychological therapy for Borderline Personality Disorder (BPD) despite a growing evidence base documenting its clinical effectiveness. This information can be used by clinicians to inform service planning and care pathways. AIMS: The aim of this study was to review published empirical research investigating the potential mechanisms underlying therapeutic change in Dialectical Behaviour Therapy (DBT) and Cognitive Behaviour Therapy (CBT) for BPD...
May 8, 2017: Journal of Mental Health
https://www.readbyqxmd.com/read/28473070/acr-appropriateness-criteria-%C3%A2-evaluation-of-nipple-discharge
#19
Su-Ju Lee, Sunita Trikha, Linda Moy, Paul Baron, Roberta M diFlorio, Edward D Green, Samantha L Heller, Anna I Holbrook, Alana A Lewin, Ana P Lourenco, Bethany L Niell, Priscilla J Slanetz, Ashley R Stuckey, Nina S Vincoff, Susan P Weinstein, Monica M Yepes, Mary S Newell
Appropriate imaging evaluation of nipple discharge depends the nature of the discharge. Imaging is not indicated for women with physiologic nipple discharge. For evaluation of pathologic nipple discharge, multiple breast imaging modalities are rated for evidence-based appropriateness under various scenarios. For women age 40 or older, mammography or digital breast tomosynthesis (DBT) should be the initial examination. Ultrasound is usually added as a complementary examination, with some exceptions. For women age 30 to 39, either mammogram or ultrasound may be used as the initial examination on the basis of institutional preference...
May 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28469438/visualization-of-breast-microcalcifications-on-digital-breast-tomosynthesis-and-2-dimensional-digital-mammography-using-specimens
#20
Jieun Byun, Jee Eun Lee, Eun Suk Cha, Jin Chung, Jeoung Hyun Kim
PURPOSE: The purpose of this study is to compare the visibility of microcalcifications of digital breast tomosynthesis (DBT) and full-field digital mammography (FFDM) using breast specimens. MATERIALS AND METHODS: Thirty-one specimens' DBT and FFDM were retrospectively reviewed by four readers. RESULTS: The image quality of microcalcifications of DBT was rated as superior or equivalent in 71.0% by reader 1, 67.8% by reader 2, 64.5% by reader 3, and 80...
2017: Breast Cancer: Basic and Clinical Research
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