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https://www.readbyqxmd.com/read/29764880/digital-breast-tomosynthesis-plus-synthesised-images-versus-standard-full-field-digital-mammography-in-population-based-screening-tosyma-protocol-of-a-randomised-controlled-trial
#1
Stefanie Weigel, Joachim Gerss, Hans-Werner Hense, Miriam Krischke, Alexander Sommer, Jörg Czwoydzinski, Horst Lenzen, Laura Kerschke, Karin Spieker, Stefanie Dickmaenken, Sonja Baier, Marc Urban, Gerold Hecht, Oliver Heidinger, Joachim Kieschke, Walter Heindel
INTRODUCTION: Development of digital breast tomosynthesis (DBT) provides a technology that generates three-dimensional data sets, thus reducing the pitfalls of overlapping breast tissue. Observational studies suggest that the combination of two-dimensional (2D) digital mammography and DBT increases diagnostic accuracy. However, because of duplicate exposure, this comes at the cost of an augmented radiation dose. This undesired adverse impact can be avoided by using synthesised 2D images reconstructed from the DBT data (s2D)...
May 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29761488/psychological-therapies-for-treatment-resistant-depression-in-adults
#2
REVIEW
Sharea Ijaz, Philippa Davies, Catherine J Williams, David Kessler, Glyn Lewis, Nicola Wiles
BACKGROUND: Antidepressants are a first-line treatment for adults with moderate to severe major depression. However, many people prescribed antidepressants for depression don't respond fully to such medication, and little evidence is available to inform the most appropriate 'next step' treatment for such patients, who may be referred to as having treatment-resistant depression (TRD). National Institute for Health and Care Excellence (NICE) guidance suggests that the 'next step' for those who do not respond to antidepressants may include a change in the dose or type of antidepressant medication, the addition of another medication, or the start of psychotherapy...
May 14, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29743941/cost-effectiveness-of-dialectical-behaviour-therapy-vs-enhanced-usual-care-in-the-treatment-of-adolescents-with-self-harm
#3
Egil Haga, Eline Aas, Berit Grøholt, Anita J Tørmoen, Lars Mehlum
Background: Studies have shown that dialectical behaviour therapy (DBT) is effective in reducing self-harm in adults and adolescents. Aims: To evaluate the cost-effectiveness of DBT for adolescents (DBT-A) compared to enhanced usual care (EUC). Methods: In a randomised study, 77 adolescents with repeated self-harm were allocated to 19 weeks of outpatient treatment, either DBT-A ( n  = 39) or EUC ( n  = 38). Cost-effective analyses, including estimation of incremental cost-effectiveness ratios, were conducted with self-harm and global functioning (CGAS) as health outcomes...
2018: Child and Adolescent Psychiatry and Mental Health
https://www.readbyqxmd.com/read/29740478/a-novel-whole-gene-deletion-of-bckdhb-by-alu-mediated-non-allelic-recombination-in-a-chinese-patient-with-maple-syrup-urine-disease
#4
Gang Liu, Dingyuan Ma, Ping Hu, Wen Wang, Chunyu Luo, Yan Wang, Yun Sun, Jingjing Zhang, Tao Jiang, Zhengfeng Xu
Maple syrup urine disease (MSUD) is an autosomal recessive inherited metabolic disorder caused by mutations in the BCKDHA, BCKDHB, DBT , and DLD genes. Among the wide range of disease-causing mutations in BCKDHB , only one large deletion has been associated with MSUD. Compound heterozygous mutations in BCKDHB were identified in a Chinese patient with typical MSUD using next-generation sequencing, quantitative PCR, and array comparative genomic hybridization. One allele presented a missense mutation (c.391G > A), while the other allele had a large deletion; both were inherited from the patient's unaffected parents...
2018: Frontiers in Genetics
https://www.readbyqxmd.com/read/29740365/the-use-of-virtual-reality-to-facilitate-mindfulness-skills-training-in-dialectical-behavioral-therapy-for-spinal-cord-injury-a-case-study
#5
Araceli Flores, Marsha M Linehan, S Rob Todd, Hunter G Hoffman
Introduction: Paralysis from a spinal cord injury (SCI) increases risk of psychological problems including suicide attempts, substance use disorder, negative emotions (e.g., anger), depression, anxiety, ASD/PTSD. Dialectical Behavioral Therapy® (DBT®) has been shown to be effective for treating similar psychological symptoms in non-SCI patient populations. The current study explored for the first time, the feasibility and clinical potential of using Immersive Virtual Reality (VR) enhanced DBT® Mindfulness skills training to help reduce psychological symptoms (negative emotions and anxiety, ASD/PTSD) of two patients with SCI...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29733057/retraso-de-la-rama-descendente-de-la-onda-t-en-electrocardiogramas-sin-datos-de-riesgo-aparente-de-muerte-s%C3%A3%C2%BAbita
#6
Cuauhtémoc Acoltzin-Vidal, Elizabeth Rabling-Arellanos
Introducción: Se ha identificado que la prolongación de la rama descendente de la onda T del electrocardiograma (ECG) puede determinar riesgo de muerte súbita de origen cardiaco, pero se desconoce su importancia en población general. Objetivo: Proporcionar una herramienta de fácil adquisición y aplicación efectiva para identificar riesgo de muerte súbita en población general. Método: Medimos el índice rdT/jT (la rama descendente de la onda T/el espacio entre el punto j y el fin de la T) en 400 electrocardiogramas (ECG) totalmente normales, 656 con alteraciones que no afectan la repolarización ventricular y 82 con bloqueo de rama...
2018: Gaceta Médica de México
https://www.readbyqxmd.com/read/29731724/suicidal-ideation-and-skill-use-during-in-patient-dialectical-behavior-therapy-for-borderline-personality-disorder-a-diary-card-study
#7
Thomas Probst, Verena Decker, Eva Kießling, Sascha Meyer, Christine Bofinger, Günter Niklewski, Andreas Mühlberger, Christoph Pieh
Associations between suicidal ideation and skill use were investigated during in-patient dialectical behavior therapy (DBT) for borderline personality disorder (BPD). Participants were N = 44 patients with BPD undergoing a 5-week in-patient DBT program in a psychiatric clinic. They filled in a diary card each treatment day resulting in 1,334 skill use ratings and 1,364 suicidal ideation ratings. Treatment days were categorized as days with successful skill use (using skills and perceiving them as effective), days with no skill use, days with unsuccessful skill use (using skills but perceiving them as ineffective)...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29730456/outcome-and-safety-analysis-of-3d-printed-patient-specific-pedicle-screw-jigs-for-complex-spinal-deformities-a-comparative-study
#8
Bhavuk Garg, Manish Gupta, Menaka Singh, Dinesh Kalyanasundaram
BACKGROUND CONTEXT: Spinal deformities are very challenging to treat and have a great risk of neurological complications due to hardware placement during corrective surgery. Various techniques have been introduced to ensure safe and accurate placement of pedicle screws. Patient-specific screw guides with pre-drawn and pre-validated trajectory seems to be an attractive option. PURPOSE: We have focused on developing 3D printing technique for complex spinal deformities in India...
May 3, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29729318/bioethanol-production-by-a-xylan-fermenting-thermophilic-isolate-clostridium-strain-dbt-ioc-dc21
#9
Nisha Singh, Munish Puri, Deepak K Tuli, Ravi P Gupta, Colin J Barrow, Anshu S Mathur
To overcome the challenges associated with combined bioprocessing of lignocellulosic biomass to biofuel, finding good organisms is essential. An ethanol producing bacteria DBT-IOC-DC21 was isolated from a compost site via preliminary enrichment culture on a pure hemicellulosic substrate and identified as a Clostridium strain by 16S rRNA analysis. This strain presented broad substrate spectrum with ethanol, acetate, lactate, and hydrogen as the primary metabolic end products. The optimum conditions for ethanol production were found to be an initial pH of 7...
May 2, 2018: Anaerobe
https://www.readbyqxmd.com/read/29724433/the-effect-of-the-addition-of-tomosynthesis-to-digital-mammography-on-reader-recall-rate-and-reader-confidence-in-the-uk-prevalent-screening-round
#10
N Upadhyay, N Soneji, V Stewart, G Ralleigh
AIM: To compare reader recall rate and confidence associated with recall decisions for digital mammography (DM) alone with DM plus digital breast tomosynthesis (DBT) in the prevalent screening round. MATERIALS AND METHODS: Following regional ethics committee approval and written informed consent from all participating women, DM and DBT were obtained. DM followed by the combination of DM plus DBT were reviewed retrospectively by one of nine radiologists, for 880 women aged between 46 and 53...
April 30, 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29723846/diagnostic-value-of-nineteen-different-imaging-methods-for-patients-with-breast-cancer-a-network-meta-analysis
#11
Xiao-Hong Zhang, Can Xiao
BACKGROUND/AIMS: We performed a network meta-analysis (NMA) to investigate and compare the diagnostic value of 19 different imaging methods used for breast cancer (BC). METHODS: Cochrane Library, PubMed and EMBASE were searched to collect the relevant literature from the inception of the study until November 2016. A combination of direct and indirect comparisons was performed using an NMA to evaluate the combined odd ratios (OR) and draw the surface under the cumulative ranking curves (SUCRA) of the diagnostic value of different imaging methods for BC...
April 28, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29723697/an-exploratory-radiomics-analysis-on-digital-breast-tomosynthesis-in-women-with-mammographically-negative-dense-breasts
#12
Alberto Stefano Tagliafico, Francesca Valdora, Giovanna Mariscotti, Maunela Durando, Jacopo Nori, Daniele La Forgia, Ilan Rosenberg, Francesca Caumo, Nicoletta Gandolfo, Nehmat Houssami, Massimo Calabrese
PURPOSE: To compare Digital Breast Tomosynthesis (DBT) for cancers and normal screens in women with dense breasts and negative mammography using a Radiomics approach. MATERIALS AND METHODS: A substudy (N = 40) of the 'Adjunct Screening With Tomosynthesis or Ultrasound in Women With Mammography-Negative Dense Breasts (ASTOUND)' trial was done based on 20 women who had DBT-detected, histology-proven, breast cancer and 20 controls matched for age and density. Using a Radiomics approach normal and pathological breast parenchyma were evaluated, and correlations among Radiomics features and clinical and prognostic parameters were investigated...
April 30, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29720582/author-correction-a-mechanistic-framework-for-auxin-dependent-arabidopsis-root-hair-elongation-to-low-external-phosphate
#13
Rahul Bhosale, Jitender Giri, Bipin K Pandey, Ricardo F H Giehl, Anja Hartmann, Richard Traini, Jekaterina Truskina, Nicola Leftley, Meredith Hanlon, Kamal Swarup, Afaf Rashed, Ute Voß, Jose Alonso, Anna Stepanova, Jeonga Yun, Karin Ljung, Kathleen M Brown, Jonathan P Lynch, Liam Dolan, Teva Vernoux, Anthony Bishopp, Darren Wells, Nicolaus von Wirén, Malcolm J Bennett, Ranjan Swarup
The original version of this Article omitted the following from the Acknowledgements: 'We also thank DBT-CREST BT/HRD/03/01/2002.' This has been corrected in both the PDF and HTML versions of the Article.
May 2, 2018: Nature Communications
https://www.readbyqxmd.com/read/29717128/author-correction-rice-auxin-influx-carrier-osaux1-facilitates-root-hair-elongation-in-response-to-low-external-phosphate
#14
Jitender Giri, Rahul Bhosale, Guoqiang Huang, Bipin K Pandey, Helen Parker, Susan Zappala, Jing Yang, Anne Dievart, Charlotte Bureau, Karin Ljung, Adam Price, Terry Rose, Antoine Larrieu, Stefan Mairhofer, Craig J Sturrock, Philip White, Lionel Dupuy, Malcolm Hawkesford, Christophe Perin, Wanqi Liang, Benjamin Peret, Charlie T Hodgman, Jonathan Lynch, Matthias Wissuwa, Dabing Zhang, Tony Pridmore, Sacha J Mooney, Emmanuel Guiderdoni, Ranjan Swarup, Malcolm J Bennett
The original version of this Article omitted the following from the Acknowledgements:'We also thank DBT-CREST BT/HRD/03/01/2002.'This has been corrected in both the PDF and HTML versions of the Article.
May 1, 2018: Nature Communications
https://www.readbyqxmd.com/read/29704965/changes-in-problematic-anger-shame-and-disgust-in-anxious-and-depressed-adults-undergoing-treatment-for-emotion-dysregulation
#15
Andrada D Neacsiu, Joscelyn Rompogren, Jeremy W Eberle, Kibby McMahon
Emotion dysregulation, the pervasive difficulty managing negative emotions, is a core problem across mood and anxiety disorders. Anger, shame, and disgust are particularly problematic emotions, impacting both disorder severity and treatment outcome. We previously found that a 16-week dialectical behavior therapy skills training group (DBT-ST) was superior to an activities-based support group (ASG) in decreasing emotion dysregulation in 44 adults with high emotion dysregulation who met diagnostic criteria for an anxiety or depressive disorder...
May 2018: Behavior Therapy
https://www.readbyqxmd.com/read/29692539/comparing-the-diagnostic-efficacy-of-full-field-digital-mammography-with-digital-breast-tomosynthesis-using-birads-score-in-a-tertiary-cancer-care-hospital
#16
Divya Singla, Arvind K Chaturvedi, Abhinav Aggarwal, S A Rao, Dibyamohan Hazarika, Vivek Mahawar
Introduction: Breast cancer is one of the leading cancers in females worldwide, and its incidence has been rising at an exponential pace in the last 10 years even in India. Mammography has been the mainstay for detection of breast cancer over decades and has gradually advanced from screen film to full-field digital mammography. Recently, tomosynthesis has evolved as an advanced imaging investigation for early diagnosis of breast lesions in both diagnostic and screening settings. Aim of Study: To compare and evaluate the impact of digital breast tomosynthesis (DBT) compared to full-field digital mammography (FFDM) in the interpretation of BIRADS score in both diagnostic and screening settings...
January 2018: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/29688873/assessing-the-marks-of-change-how-psychotherapy-alters-the-brain-structure-in-women-with-borderline-personality-disorder
#17
Falk Mancke, Ruth Schmitt, Dorina Winter, Inga Niedtfeld, Sabine C Herpertz, Christian Schmahl
BACKGROUND: There is increasing evidence that psychotherapy can alter the function of the brain of patients with borderline personality disorder (BPD). However, it is not known whether psychotherapy can also modify the brain structure of patients with BPD. METHODS: We used structural MRI data of female patients with BPD before and after participation in 12 weeks of residential dialectical behavioural therapy (DBT) and compared them to data from female patients with BPD who received treatment as usual (TAU)...
May 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/29687870/dl-3-n-butylphthalide-protects-the-blood-brain-barrier-of-cerebral-infarction-by-activating-the-nrf-2-ho-1-signaling-pathway-in-mice
#18
Y-J Zhao, Y Nai, Q-S Ma, D-J Song, Y-B Ma, L-H Zhang, L-X Mi
OBJECTIVE: The aim of this study was to explore whether Dl-3-n-butylphthalide (DBT) could protect blood-brain barrier (BBB) of mice with experimental cerebral infarction and the relevant mechanism. MATERIALS AND METHODS: Adult male CD-1 mice were selected as the study objects. The permanent middle cerebral artery occlusion (MCAO) model was prepared by Longa's modified suture-occluded method. The mice were randomly divided into 3 groups: the sham operation group (Sham group), the cerebral infarction model group (CI group) and the DBT (120 mg/kg) intervention group (DBT group)...
April 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29665537/mass-detection-in-digital-breast-tomosynthesis-data-using-convolutional-neural-networks-and-multiple-instance-learning
#19
Mina Yousefi, Adam Krzyżak, Ching Y Suen
Digital breast tomosynthesis (DBT) was developed in the field of breast cancer screening as a new tomographic technique to minimize the limitations of conventional digital mammography breast screening methods. A computer-aided detection (CAD) framework for mass detection in DBT has been developed and is described in this paper. The proposed framework operates on a set of two-dimensional (2D) slices. With plane-to-plane analysis on corresponding 2D slices from each DBT, it automatically learns complex patterns of 2D slices through a deep convolutional neural network (DCNN)...
April 12, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29651723/sulfur-extraction-from-liquid-fuels-using-trihexyl-tetradecyl-phosphonium-tetrafluoroborate-as-promising-solvent
#20
Swapnil Dharaskar, Mika Sillanpaa, Kiran Kumar Tadi
Sulfur extraction from fuel is essential to be done for environmental and industrial point of view. Extractive desulfurization (EDS) is one of the most promising techniques in order to achieve legislative sulfur content requirements. Among numerous extractants and solvents, ionic liquids (ILs) are more capable due to their desirable green solvent properties. This work demonstrated that trihexyl(tetradecyl)phosphonium tetrafluoroborate ([THTDP]BF4 ) was synthesized, characterized, and employed as extraction solvent for extraction of dibenzothiophene (DBT), thiophene, benzothiophene, and other alkyl-substituted derivatives of sulfur from liquid fuel...
April 12, 2018: Environmental Science and Pollution Research International
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