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https://www.readbyqxmd.com/read/28806573/digital-breast-tomosynthesis-vacuum-assisted-biopsy-for-tomosynthesis-detected-sonographically-occult-lesions
#1
Nikki S Ariaratnam, Sherrill T Little, Markus A Whitley, Kristy Ferguson
PURPOSE: To assess the utility and pathological results from DBT VAB for lesions occult on 2D mammography and breast ultrasound (US). MATERIALS AND METHODS: A retrospective review of 1116 consecutive stereotactic biopsies was performed over 27months. DBT VAB was performed for 38 non-calcified lesions which were solely detected using DBT. Imaging findings and pathology results were reviewed. RESULTS: Pathologic findings were malignant in 8 of 38 lesions [masses (5) and distortion (3)]...
August 5, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28799955/a-serotonergic-deficit-in-the-dorsal-periaqueductal-gray-matter-may-underpin-enhanced-panic-like-behavior-in-diabetic-rats
#2
Eder Gambeta, Caio C Sestile, Manoela V Fogaça, Francisco S Guimarães, Elisabeth A Audi, Joice M da Cunha, Hélio Zangrossi, Paula Shimene de Melo Yamashita, Janaina M Zanoveli
It is known that diabetic (DBT) animals present dysregulation on the serotonergic system in several brain areas associated with anxiety-like responses. The aim of this study was to investigate the involvement of 5-HT1A receptors on dorsal periaqueductal gray (dPAG) in the behavioral response related to panic disorder in type-1 DBT animals. For this, the escape response by electric stimulation (ES) of dPAG in DBT and normoglycemic (NGL) animals was assessed. Both NGL and DBT animals were exposed to an open-field test (OFT) 28 days after DBT confirmation...
August 9, 2017: Behavioural Pharmacology
https://www.readbyqxmd.com/read/28783629/low-dose-contrast-enhanced-breast-ct-using-spectral-shaping-filters-an-experimental-study
#3
Andrey Makeev, Stephen J Glick
Iodinated contrast-enhanced x-ray imaging of the breast has been studied with various modalities including, fullfield digital mammography (FFDM), digital breast tomosynthesis (DBT), and dedicated breast CT (BCT). Contrast imaging with breast CT has a number of advantages over FFDM and DBT including the lack of breast compression, and generation of fully isotropic, three-dimensional reconstructions. Nonetheless, for breast CT to be considered as a viable tool for routine clinical use, it would be desirable to reduce radiation dose...
August 2, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28783602/organotin-compounds-in-brachidontes-rodriguezii-mussels-from-the-bah%C3%A3-a-blanca-estuary-argentina
#4
Pamela Y Quintas, Andrés H Arias, Ana L Oliva, Claudia E Domini, Mónica B Alvarez, Mariano Garrido, Jorge E Marcovecchio
Levels of tributyltin and its breakdown compounds, including the first record of monobutyltin (MBT) in history for Latin America, were determined in native mussels (Brachidontes rodriguezii) by means of CG-MS, after extraction/derivatization assisted by ultrasound. The samples were collected in 2013 in Bahía Blanca Estuary (Argentina) at 6 sites, which reflect different levels of maritime activities. Total butyltins (TBts = TBT+ DBT+ MBT) levels ranged from 19.64 to 180.57ng Sn g(-1) dry weight. According to the Oslo-Paris commission, the results indicated that 73...
August 4, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28780702/clinical-implementation-of-synthesized-mammography-with-digital-breast-tomosynthesis-in-a-routine-clinical-practice
#5
Phoebe E Freer, Joanna Riegert, Laura Eisenmenger, Dominik Ose, Nicole Winkler, Matthew A Stein, Gregory J Stoddard, Rachel Hess
BACKGROUND: Most published studies evaluating digital breast tomosynthesis (DBT) included a separate 2-dimensional full-field digital mammogram (FFDM) for DBT screening protocols, increasing radiation from screening mammography. Synthesized mammography (SM) creates a 2-dimensional image from the DBT source data, and if used in place of FFDM, it reduces radiation of DBT screening. This study evaluated the implementation of SM + DBT in routine screening practice in terms of recall rates, cancer detection rates (CDR), % of minimal cancers, % of node-positive cancers, and positive predictive values (PPV)...
August 5, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28768765/crystal-structures-of-tdsc-a-dibenzothiophene-monooxygenase-from-the-thermophile-paenibacillus-sp-a11-2-reveal-potential-for-expanding-its-substrate-selectivity
#6
Tomoya Hino, Haruka Hamamoto, Hirokazu Suzuki, Hisashi Yagi, Takashi Ohshiro, Shingo Nagano
Sulfur compounds in fossil fuels are a major source of environmental pollution, and microbial desulfurization has emerged as a promising technology for removing sulfur under mild conditions. The enzyme TdsC from the thermophile Paenibacillus sp. A11-2 is a two-component Flavin-dependent monooxygenase that catalyzes the oxygenation of dibenzothiophene (DBT) to its sulfoxide (DBTO) and sulfone (DBTO2) during microbial desulfurization. The crystal structures of the apo and flavin mononucleotide (FMN)-bound forms of DszC, an ortholog of TdsC, were previously determined, although the structure of the ternary substrate-FMN-enzyme complex remained unknown...
August 2, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28767366/detector-blur-and-correlated-noise-modeling-for-digital-breast-tomosynthesis-reconstruction
#7
Jiabei Zheng, Jeffrey A Fessler, Heang-Ping Chan
This paper describes a new image reconstruction method for digital breast tomosynthesis (DBT). The new method incorporates detector blur into the forward model. The detector blur in DBT causes correlation in the measurement noise. By making a few approximations that are reasonable for breast imaging, we formulated a regularized quadratic optimization problem with a data-fit term that incorporates models for detector blur and correlated noise (DBCN). We derived a computationally efficient separable quadratic surrogate (SQS) algorithm to solve the optimization problem that has a non-diagonal noise covariance matrix...
July 27, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28760363/strategies-for-decreasing-screening-mammography-recall-rates-while-maintaining-performance-metrics
#8
Lisa A Mullen, Babita Panigrahi, Jacqueline Hollada, Benita Panigrahi, Eniola T Falomo, Susan C Harvey
RATIONALE AND OBJECTIVE: This study aimed to determine the impact of interventions designed to reduce screening mammography recall rates on screening performance metrics. MATERIALS AND METHODS: We assessed baseline performance for full-field digital mammography (FFDM) and digital breast tomosynthesis mammography (DBT) for a 3-year period before intervention. The first intervention sought to increase awareness of recalls from screening mammography. Breast imagers discussed their perceptions regarding screening recalls and were required to review their own recalled cases, including outcomes of diagnostic evaluation and biopsy...
July 28, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28717512/trauma-related-emotions-and-radical-acceptance-in-dialectical-behavior-therapy-for-posttraumatic-stress-disorder-after-childhood-sexual-abuse
#9
Nora Görg, Kathlen Priebe, Jan R Böhnke, Regina Steil, Anne S Dyer, Nikolaus Kleindienst
BACKGROUND: Posttraumatic Stress Disorder (PTSD) related to childhood sexual abuse (CSA) is often associated with a wide range of trauma-related aversive emotions such as fear, disgust, sadness, shame, guilt, and anger. Intense experience of aversive emotions in particular has been linked to higher psychopathology in trauma survivors. Most established psychosocial treatments aim to reduce avoidance of trauma-related memories and associated emotions. Interventions based on Dialectical Behavior Therapy (DBT) also foster radical acceptance of the traumatic event...
2017: Borderline Personality Disorder and Emotion Dysregulation
https://www.readbyqxmd.com/read/28716454/a-randomised-trial-of-screening-with-digital-breast-tomosynthesis-plus-conventional-digital-2d-mammography-versus-2d-mammography-alone-in-younger-higher-risk-women
#10
Anthony J Maxwell, Michael Michell, Yit Y Lim, Susan M Astley, Mary Wilson, Emma Hurley, D Gareth Evans, Anthony Howell, Asif Iqbal, John Kotre, Stephen Duffy, Julie Morris
INTRODUCTION: Digital breast tomosynthesis (DBT) has been shown to increase invasive cancer detection rates at screening compared to full field digital (2D) mammography alone, and some studies have reported a reduction in the screening recall rate. No prospective randomised studies of DBT have previously been published. This study compares recall rates with 2D mammography with and without concurrent DBT in women in their forties with a family history of breast cancer undergoing incident screening...
June 30, 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28715278/bi-rads-category-3-comparison-probably-benign-category-after-recall-from-screening-before-and-after-implementation-of-digital-breast-tomosynthesis
#11
Elizabeth S McDonald, Anne Marie McCarthy, Susan P Weinstein, Mitchell D Schnall, Emily F Conant
Purpose To evaluate Breast Imaging Reporting and Data System (BI-RADS) category 3 assessment at diagnostic examination after recall from screening in a large urban population after implementation of digital breast tomosynthesis (DBT) by focusing both on overall use and use stratified by recalled finding type and outcome at 2 years. Materials and Methods This was an intuitional review board-approved and HIPAA-compliant retrospective review of 10 728 digital mammography (DM) examinations from September 1, 2010, to August 30, 2011, and 15 571 screening DBT examinations from October 1, 2011, to February 28, 2013...
July 17, 2017: Radiology
https://www.readbyqxmd.com/read/28710582/comparison-of-digital-mammography-and-digital-breast-tomosynthesis-in-the-detection-of-architectural-distortion
#12
Elizabeth H Dibble, Ana P Lourenco, Grayson L Baird, Robert C Ward, A Stanley Maynard, Martha B Mainiero
OBJECTIVES: To compare interobserver variability (IOV), reader confidence, and sensitivity/specificity in detecting architectural distortion (AD) on digital mammography (DM) versus digital breast tomosynthesis (DBT). METHODS: This IRB-approved, HIPAA-compliant reader study used a counterbalanced experimental design. We searched radiology reports for AD on screening mammograms from 5 March 2012-27 November 2013. Cases were consensus-reviewed. Controls were selected from demographically matched non-AD examinations...
July 14, 2017: European Radiology
https://www.readbyqxmd.com/read/28707529/interpretation-of-digital-breast-tomosynthesis-preliminary-study-on-comparison-with-picture-archiving-and-communication-system-pacs-and-dedicated-workstation
#13
Young Seon Kim, Jung Min Chang, Ann Yi, Sung Ui Shin, Myung Eun Lee, Won Hwa Kim, Nariya Cho, Woo Kyung Moon
OBJECTIVES: To compare the diagnostic accuracy and efficiency in the interpretation of digital breast tomosynthesis (DBT) images using picture archiving and communication system (PACS) and a dedicated workstation. METHODS: A total of 97 DBT images performed for screening or diagnostic purposes were stored in both a workstation and PACS, and evaluated in combination with digital mammography by three independent radiologists retrospectively. Breast Imaging Reporting and Data System final assessments and likelihood of malignancy (%) were assigned and the interpretation time when using the workstation and PACS was recorded...
July 14, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28701090/-transference-focused-psychotherapy-for-borderline-adolescents-in-a-day-clinic-treatment-program
#14
Maya Krischer, Tamara Ponton-Rodriguez, Ghazal Rostami Gooran, Stephan Bender
Transference Focused Psychotherapy for Borderline-Adolescents in a Day Clinic Treatment Program This paper focuses on the concept of transference focused psychotherapy (TFP) modified for juvenile borderline patients. Adolescents with borderline developmental personality disorder (bpd) have an essential deficit in their personality structure that leads to oscillations in their self-esteem and in a "split" perception of the world. They suffer from a variety of symptoms and severe impairments on their own and their families' quality of life...
July 2017: Praxis der Kinderpsychologie und Kinderpsychiatrie
https://www.readbyqxmd.com/read/28696192/breast-cancer-screening-does-tomosynthesis-augment-mammography
#15
REVIEW
Traci A Takahashi, Christoph I Lee, Kay M Johnson
Digital breast tomosynthesis (DBT) is a relatively new imaging technology that is being adopted widely for breast cancer screening. Initial evidence suggests that it may reduce recall rates and increase cancer detection rates when added to digital mammography screening. However, more rigorous, prospective studies are needed to determine whether it improves long-term clinical outcomes of breast cancer screening.
July 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28690851/combining-emotion-regulation-and-mindfulness-skills-for-preventing-depression-relapse-a-randomized-controlled-study
#16
Matilde Elices, Joaquim Soler, Albert Feliu-Soler, Cristina Carmona, Thais Tiana, Juan C Pascual, Azucena García-Palacios, Enric Álvarez
BACKGROUND: Dialectical behavioral therapy (DBT) skills have become increasingly used to treat several psychiatric conditions, including major depressive disorder (MDD). The aim of the study was to investigate the efficacy of an intervention that combines emotion regulation and mindfulness skills of DBT to prevent depression relapse/recurrence. METHODS: A total of 75 individuals (79% females; mean age, 52 years) with a diagnosis of MDD in complete or partial remission were recruited...
2017: Borderline Personality Disorder and Emotion Dysregulation
https://www.readbyqxmd.com/read/28688342/estrogen-mediated-protection-of-the-organotin-degrading-strain-metarhizium-robertsii-against-oxidative-stress-promoted-by-monobutyltin
#17
Paulina Siewiera, Sylwia Różalska, Przemysław Bernat
Dibutyltin (DBT) is a global pollutant characterized by pro-oxidative properties. The fungal strain Metarhizium robertsii can eliminate high levels of DBT efficiently. In this study, induction of oxidative stress as well as its alleviation through the application of natural estrogens during the elimination of DBT by M. robertsii were evaluated. During the first 24 h of incubation, the initial concentration of DBT (20 mg l(-1)) was reduced to 3.1 mg l(-1), with simultaneous formation of a major byproduct - monobutyltin (MBT)...
June 30, 2017: Chemosphere
https://www.readbyqxmd.com/read/28668424/digital-breast-tomosynthesis-versus-full-field-digital-mammography-which-modality-provides-more-accurate-prediction-of-margin-status-in-specimen-radiography
#18
Heba A Amer, Florian Schmitzberger, Barbara Ingold-Heppner, Julia Kussmaul, Manal F El Tohamy, Hazim I Tantawy, B Hamm, M Makowski, Eva M Fallenberg
OBJECTIVES: To evaluate the reliability of tumor margin assessment in specimen radiography (SR) using digital breast tomosynthesis (DBT) and full-field digital mammography (FFDM) in comparison to postoperative histopathology margin status as the gold standard. METHODS: After ethics committee approval, 102 consecutive patients who underwent breast conservative surgery for nonpalpable proven breast cancer were prospectively included. All patients underwent ultrasound/mammography-guided wire localization of their lesions...
August 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28654786/l-proline-based-deep-eutectic-solvents-dess-for-deep-catalytic-oxidative-desulfurization-ods-of-diesel
#19
Lingwan Hao, Meiri Wang, Wenjuan Shan, Changliang Deng, Wanzhong Ren, Zhouzhou Shi, Hongying Lü
A series of L-proline-based DESs was prepared through an atom economic reaction between L-proline (L-Pro) and four different kinds of organic acids. The DESs were characterized by Fourier transform infrared spectroscopy (FT-IR), H nuclear magnetic resonance ((1)HNMR), cyclic voltammogram (CV) and the Hammett method. The synthesized DESs were used for the oxidative desulfurization and the L-Pro/p-toluenesultonic acid (L-Pro/p-TsOH) system shows the highest catalytic activity that the removal of dibenzothiophene (DBT) reached 99% at 60°C in 2h, which may involve the dual activation of the L-Pro/p-TsOH...
June 21, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28649383/impact-of-therapist-change-after-initial-contact-and-traumatic-burden-on-dropout-in-a-naturalistic-sample-of-inpatients-with-borderline-pathology-receiving-dialectical-behavior-therapy
#20
Carolin Steuwe, Michaela Berg, Martin Driessen, Thomas Beblo
BACKGROUND: This study focused on the predictors of therapy dropout in a naturalistic sample of patients with borderline pathology receiving dialectical behavior therapy (DBT) in an inpatient setting. We assumed that the change of the therapist between DBT-briefing and start of DBT-treatment as well as comorbid posttraumatic stress disorder (PTSD) and childhood trauma history were associated with elevated dropout. METHODS: Eighty-nine participants with borderline pathology (≥ 3 borderline personality disorder criteria) receiving an inpatient DBT program completed a quality assurance questionnaire set assessing demographic information and pretreatment psychopathology during the days of their inpatient stay...
2017: Borderline Personality Disorder and Emotion Dysregulation
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