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https://www.readbyqxmd.com/read/28214227/automated-breast-density-computation-in-digital-mammography-and-digital-breast-tomosynthesis-influence-on-mean-glandular-dose-and-birads-density-categorization
#1
Maria Castillo-García, Margarita Chevalier, Julia Garayoa, Alejandro Rodriguez-Ruiz, Diego García-Pinto, Julio Valverde
RATIONALE AND OBJECTIVES: The study aimed to compare the breast density estimates from two algorithms on full-field digital mammography (FFDM) and digital breast tomosynthesis (DBT) and to analyze the clinical implications. MATERIALS AND METHODS: We selected 561 FFDM and DBT examinations from patients without breast pathologies. Two versions of a commercial software (Quantra 2D and Quantra 3D) calculated the volumetric breast density automatically in FFDM and DBT, respectively...
February 14, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28211806/digital-breast-tomosynthesis-plus-mammography-magnetic-resonance-imaging-plus-mammography-and-mammography-alone-a-comparison-of-diagnostic-performance-in-symptomatic-women
#2
Wei Tang, Fei-Xiang Hu, Hui Zhu, Qi-Feng Wang, Ya-Jia Gu, Wei-Jun Peng
PURPOSE: To compare the diagnostic efficiency of digital breast tomosynthesis (DBT) plus digital mammography (DM) and magnetic resonance imaging (MRI) plus DM in symptomatic women. MATERIALS AND METHODS: The protocol used in our study was accepted by the ethics committee at our hospital, and informed consent was obtained from all patients. Between June and December 2014, 197 patients with 238 histologically proven lesions all underwent DM, DBT and MRI. Two radiologists were responsible for interpreting all images according to the Breast Imaging Reporting and Data System (BI-RADS)...
February 17, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28205250/crystal-structure-of-dibenzothiophene-sulfone-monooxygenase-bdsa-from-bacillus-subtilis-wu-s2b
#3
Masahiko Okai, Woo Cheol Lee, Li-Jun Guan, Takashi Ohshiro, Yoshikazu Izumi, Masaru Tanokura
The dibenzothiophene (DBT) sulfone monooxygenase BdsA from Bacillus subtilis WU-S2B catalyzes the conversion of DBT sulfone to 2'-hydroxybiphenyl 2-sulfinate (HBPS). We report the crystal structures of BdsA at a resolution of 2.80 Å. BdsA exists as a homotetramer with a dimer-of-dimers configuration in the crystal, and the interaction between E288 and R296 in BdsA is important for tetramer formation. A structural comparison with homologous proteins shows that the orientation and location of the α9-α12 helices in BdsA are closer to those of the closed form than those of the open form in the EDTA monooxygenase EmoA...
February 16, 2017: Proteins
https://www.readbyqxmd.com/read/28202601/cell-scientist-to-watch-arun-shukla
#4
(no author information available yet)
Arun Shukla received his master's degree in Biotechnology from the Jawaharlal Nehru University in New Delhi, and joined the lab of Nobel laureate Hartmut Michel at the Max Planck Institute of Biophysics in Frankfurt, Germany, for his PhD. He then moved to the United States for his postdoctoral work with Robert Lefkowitz at Duke University (Durham, NC) in a very close collaboration with Brian Kobilka (Stanford University, CA). Arun became an Assistant Professor in the Department of Medicine at Duke University in 2011, before returning to India in April 2014 as an Assistant Professor at the Indian Institute of Technology (IIT) in Kanpur as a Wellcome Trust DBT India Alliance Intermediate Fellow...
February 15, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28197878/two-homozygous-mutations-in-the-exon-5-of-bckdhb-gene-that-may-cause-the-classic-form-of-maple-syrup-urine-disease
#5
Ling Su, Zhikun Lu, Fatao Li, Yongxian Shao, Huiying Sheng, Yanna Cai, Li Liu
Maple syrup urine disease (MSUD) is a rare autosomal recessive genetic disorder caused by defects in the catabolism of the branched-chain amino acids (BCAAs). Classic form of MSUD (CMSUD) is caused by mutations in BCKDHA, BCKDHB, DBT genes mostly. In this study, we analyzed the clinical and genetic characteristics of two patients with CMSUD. Two homozygous mutations, c.517G > T (p.Asp173Tyr) and c.503G > A (p.Arg168His), both in the exon 5 of BCKDHB were detected respectively. The novel mutation p...
February 15, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28197085/anodal-transcranial-direct-current-stimulation-does-not-facilitate-dynamic-balance-task-learning-in-healthy-old-adults
#6
Elisabeth Kaminski, Maike Hoff, Viola Rjosk, Christopher J Steele, Christopher Gundlach, Bernhard Sehm, Arno Villringer, Patrick Ragert
Older adults frequently experience a decrease in balance control that leads to increased numbers of falls, injuries and hospitalization. Therefore, evaluating older adults' ability to maintain balance and examining new approaches to counteract age-related decline in balance control is of great importance for fall prevention and healthy aging. Non-invasive brain stimulation techniques such as transcranial direct current stimulation (tDCS) have been shown to beneficially influence motor behavior and motor learning...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28188043/digital-breast-tomosynthesis-practice-patterns-following-2011-fda-approval-a-survey-of-breast-imaging-radiologists
#7
Yiming Gao, James S Babb, Hildegard K Toth, Linda Moy, Samantha L Heller
RATIONALE AND OBJECTIVES: To evaluate uptake, patterns of use, and perception of digital breast tomosynthesis (DBT) among practicing breast radiologists. MATERIALS AND METHODS: Institutional Review Board exemption was obtained for this Health Insurance Portability and Accountability Act-compliant electronic survey, sent to 7023 breast radiologists identified via the Radiological Society of North America database. Respondents were asked of their geographic location and practice type...
February 7, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28181141/does-post-operative-psychotherapy-contribute-to-improved-comorbidities-in-bariatric-patients-with-borderline-personality-disorder-traits-and-bulimia-tendencies-a-prospective-study
#8
Francesca Gallé, Pietro Maida, Assunta Cirella, Elena Giuliano, Patrizia Belfiore, Giorgio Liguori
BACKGROUND: Borderline personality disorder (BPD) and eating disorders may affect the outcomes of bariatric surgery. This study was aimed to evaluate the influence of a post-operative dialectical behavioral therapy (DBT) intervention on weight loss and comorbidities in a sample of comorbid obese Italian patients with BPD traits and bulimia tendencies who underwent laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic adjustable gastric banding (LAGB). METHODS: One hundred fifty-four LRYGB or LAGB patients showing BPD and bulimia traits and type II diabetes, hypertension, and/or sleep apnea (OSAS) voluntarily adhered to DBT (n = 72) or treatment as usual (n = 82) for 12 months after surgery...
February 8, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28180927/short-segment-coil-embolization-using-a-double-balloon-technique-in-an-experimental-vascular-model
#9
Daisuke Yunaiyama, Toru Saguchi, Tomohisa Moriya, Natsuhiko Shirota, Jun Otaka, Koichi Tokuuye, Yuichi Nagakawa, Akihiko Tsuchida, Kazuhiro Saito
PURPOSE: To evaluate the feasibility of short-segment coil embolization between 2 balloons for tight packing in an experimental vascular model. MATERIALS AND METHODS: Three coil embolization techniques were performed by 5 interventional radiologists as follows: (1) proximal balloon technique (proximal BT) which involved proximal balloon inflation and coil deployment over the balloon, (2) distal balloon technique (distal BT) which involved distal balloon inflation and coil deployment at the proximal side of the inflated balloon, and (3) double-balloon technique (DBT) which involved coil deployment between 2 inflated balloons...
February 8, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28177646/digital-breast-tomosynthesis-cost-effectiveness-of-using-private-and-medicare-insurance-in-community-based-health-care-facilities
#10
Sara A Hunter, Colleen Morris, Karl Nelson, Brandon J Snyder, Thomas B Poulton
OBJECTIVE: The purpose of this study was to determine whether digital breast tomosynthesis (DBT) is a cost-effective alternative to full-field digital mammography (FFDM) for both Medicare and privately insured patients undergoing screening mammography. MATERIALS AND METHODS: A retrospective data analysis was performed between July 15, 2013, and July 14, 2014, with data on women presenting for screening mammography that included any additional radiologic workup (n = 6319)...
February 8, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28168608/barriers-facilitators-and-benefits-of-implementation-of-dialectical-behavior-therapy-in-routine-care-results-from-a-national-program-evaluation-survey-in-the-veterans-health-administration
#11
Sara J Landes, Allison L Rodriguez, Brandy N Smith, Monica M Matthieu, Lindsay R Trent, Janet Kemp, Caitlin Thompson
National implementation of evidence-based psychotherapies (EBPs) in the Veterans Health Administration (VHA) provides important lessons on the barriers and facilitators to implementation in a large healthcare system. Little is known about barriers and facilitators to the implementation of a complex EBP for emotional and behavioral dysregulation-dialectical behavioral therapy (DBT). The purpose of this study was to understand VHA clinicians' experiences with barriers, facilitators, and benefits from implementing DBT into routine care...
February 6, 2017: Translational Behavioral Medicine
https://www.readbyqxmd.com/read/28163116/danggui-buxue-tang-astragali-radix-and-angelicae-sinensis-radix-for-menopausal-symptoms-a-review
#12
REVIEW
Huang Q Lin, Amy Gw Gong, Huai Y Wang, Ran Duan, Tina Tx Dong, Kui J Zhao, Karl Wk Tsim
BACKGROUND: Traditional Chinese medicine (TCM) has contributed greatly to human health in past several thousand years. Today, the development of TCM is facing two obstacles: (i) quality control of herbal extract; and (ii) action mechanisms not known. OBJECTIVES: Among thousands of complex TCM formulations, Danggui Buxue Tang (DBT) is the simplest one. DBT is used to treat ailments in women and contains only two herbs, Astragali Radix (Huangqi; AR) and Angelicae Sinensis Radix (Danggui; ASR)...
February 2, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28160180/the-importance-of-environmental-factors-and-matrices-in-the-adsorption-desorption-and-toxicity-of-butyltins-a-review
#13
Liping Fang, Cuihong Xu, Ji Li, Ole K Borggaard, Dongsheng Wang
Butyltins (BTs) are considered as a group of the most important organometallic compounds in industry and agriculture. Due to their widespread use, large amounts of BTs including tributyltin (TBT), dibutyltin (DBT), and monobutyltin (MBT) have entered into the environment, and subsequently causing detrimental effects on humans and aquatic organisms. This work provides a critical review of recent studies on the adsorption, desorption, bioaccumulation, and toxicity of BTs that can notably influence the distribution of BTs in the environment...
February 4, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28157453/book-review-changing-behavior-in-dbt-problem-solving-in-action-changing-behavior-in-dbt-problem-solving-in-action-heard-heidi-l-swales-michaela-a-new-york-ny-guilford-2016-266-p-us-29-75
#14
Gail Myhr
No abstract text is available yet for this article.
February 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/28151728/optimization-of-digital-breast-tomosynthesis-dbt-acquisition-parameters-for-human-observers-effect-of-reconstruction-algorithms
#15
Rongping Zeng, Aldo Badano, Kyle Myers
We showed in our earlier work that the choice of reconstruction methods does not affect the optimization of DBT acquisition parameters (angular span and number of views) using simulated breast phantom images in detecting lesions with a channelized Hoteling observer (CHO). In this work we investigate whether the model-observer based conclusion is valid when using humans to interpret images. We used previously generated DBT breast phantom images and recruited human readers to find the optimal geometry settings associated with two reconstruction algorithms, filtered back projection (FBP) and simultaneous algebraic reconstruction technique (SART)...
February 2, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28151431/characterisation-of-noise-and-sharpness-of-images-from-four-digital-breast-tomosynthesis-systems-for-simulation-of-images-for-virtual-clinical-trials
#16
Alistair Mackenzie, Nicholas Marshall, Andria Hadjipanteli, David Dance, Hilde Bosmans, Kenneth Young
In-depth evaluation of the noise and sharpness characteristics of FujiFilm Innovality, GE SenoClaire, Hologic Selenia Dimensions and Siemens Inspiration digital breast tomosynthesis (DBT) systems was performed with the intention of improving image simulation for virtual clinical trials. Noise power spectra (NPS) and modulation transfer function curves (MTF) were measured for planar modes and for the first and central projections for DBT modes. In DBT mode, the x-ray beam was blocked for the projections before the central projection in order to remove the influence of lag and ghosting from the previous images...
February 2, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28142632/-dialectical-behavioral-therapy-for-male-adolescents-with-borderline-symptomatology
#17
Jens Heider, Anna Fleck, Christina Peteler, Sabine Anker, Susanne Lieb, Michael Behrens, Annette Schröder, Tina In-Albon, Michael Brünger
Dialectical Behavioral Therapy for Male Adolescents with Borderline Symptomatology The efficacy of Dialectical Behavior Therapy for adolescents (DBT-A) in patients with borderline symptomatology has mainly been shown in female adolescents. However, male adolescents with borderline symptoms are characterized by more aggressive, disruptive, and antisocial behavior. Therefore, the efficacy of the DBT-A has to be investigated in male adolescents. The DBT-A manual was adopted for male adolescents in an inpatient setting...
February 2017: Praxis der Kinderpsychologie und Kinderpsychiatrie
https://www.readbyqxmd.com/read/28141582/radiation-shielding-calculation-for-digital-breast-tomosynthesis-rooms-with-an-updated-workload-survey
#18
Kai Yang, Thomas J Schultz, Xinhua Li, Bob Liu
PURPOSE: To present shielding calculations for clinical digital breast tomosynthesis (DBT) rooms with updated workload data from a comprehensive survey and to provide reference shielding data for DBT rooms. METHODS: The workload survey was performed from eight clinical DBT (Hologic Selenia Dimensions) rooms at Massachusetts General Hospital (MGH) for the time period between 10/1/2014 and 10/1/2015. Radiation output related information tags from the DICOM header, including mAs, kVp, beam filter material and gantry angle, were extracted from a total of 310 421 clinical DBT acquisitions from the PACS database...
January 31, 2017: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/28139412/value-analysis-of-digital-breast-tomosynthesis-for-breast-cancer-screening-in-a-us-medicaid-population
#19
Jeffrey D Miller, Machaon M Bonafede, Sally D Herschorn, Scott K Pohlman, Kathleen A Troeger, Laurie L Fajardo
PURPOSE: Better understanding regarding the clinical-economic value of digital breast tomosynthesis (DBT) for breast cancer screening for Medicaid enrollees is needed to help inform sound, value-based decision making. The objective of this study was to conduct a clinical-economic value analysis of DBT for breast cancer screening among women enrolled in Medicaid to assess the potential clinical benefits, associated expenditures, and net budget impact of DBT. METHODS: Two annual screening mammography scenarios were evaluated with an economic model: (1) full-field digital mammography and (2) combined full-field digital mammography and DBT...
January 26, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28131937/inland-navigation-pah-inventories-in-soil-and-vegetation-after-eu-fuel-regulation-2009-30-ec
#20
Melanie Bläsing, Wulf Amelung, Lorenz Schwark, Eva Lehndorff
In January 2011, fuel quality in inland water vessels was changed by EU regulation 2009/30/EC, aiming at improving air quality along waterways. We hypothesized that the implementation of this regulation both lowered the total deposition of polycyclic aromatic hydrocarbons (PAHs) and changed their composition in river valleys. We analyzed parent-, alkylated- and thio-PAHs in soil and vine leaves, at two waterways (Rhine and Moselle, Germany), as well as in one ship-free reference area (Ahr, Germany). Samples were taken annually (2010-2013) in transects perpendicular to the rivers...
January 26, 2017: Science of the Total Environment
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