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https://www.readbyqxmd.com/read/27922541/effects-of-the-5-ht1a-receptor-agonists-buspirone-and-8-oh-dpat-on-pupil-size-in-common-marmosets
#1
Manato Kotani, Naoko Urushino, Itaru Natsutani, Yuji Ogi, Kazuhito Ikeda
As pupil size is affected by psychotropic drugs in all mammals, it has been used as a well-established clinical indicator for the preclinical and clinical development of novel drugs. It has been reported that activation of the serotonin (5-HT)1A receptor differently affects pupil response in rodents (mydriasis) and humans (miosis). Thus, it is important to establish a quantitative system for measuring pupil size using other species, such as nonhuman primates. Common marmosets have recently attracted a great deal of attention as suitable experimental animals in the psychoneurological field because of handling ease compared with other nonhuman primates and the requirement for small amounts of test drugs...
December 2, 2016: Behavioural Pharmacology
https://www.readbyqxmd.com/read/27920145/three-small-receptive-field-ganglion-cells-in-the-mouse-retina-are-distinctly-tuned-to-size-speed-and-object-motion
#2
Jason Jacoby, Gregory W Schwartz
: Retinal ganglion cells (RGCs) are frequently divided into functional types by their ability to extract and relay specific features from a visual scene, such as the capacity to discern local or global motion, direction of motion, stimulus orientation, contrast or uniformity, or the presence of large or small objects. Here we introduce three previously uncharacterized, non-direction selective ON-OFF RGC types that represent a distinct set of feature detectors in the mouse retina. The three high definition (HD) RGCs possess small receptive field (RF) centers and strong surround suppression...
December 5, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27919005/tracking-listeria-monocytogenes-contamination-and-virulence-associated-characteristics-in-the-ready-to-eat-meat-based-food-products-industry-according-to-the-hygiene-level
#3
A R Henriques, L T Gama, M J Fraqueza
Listeria monocytogenes isolates collected from final products and food contact surfaces of 10 ready-to-eat meat-based food products (RTEMP) producing industries were analyzed to relate their virulence-associated characteristics and genetic profiles with the hygiene assessment of those industries. Together with sample collection, an audit was performed to evaluate the implemented food safety management system and to investigate the specific audit requisites more associated to the occurrence of those L. monocytogenes serogroups frequently related with human disease...
November 21, 2016: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/27916856/a-novel-gravity-compensation-method-for-high-precision-free-ins-based-on-extreme-learning-machine
#4
Xiao Zhou, Gongliu Yang, Qingzhong Cai, Jing Wang
In recent years, with the emergency of high precision inertial sensors (accelerometers and gyros), gravity compensation has become a major source influencing the navigation accuracy in inertial navigation systems (INS), especially for high-precision INS. This paper presents preliminary results concerning the effect of gravity disturbance on INS. Meanwhile, this paper proposes a novel gravity compensation method for high-precision INS, which estimates the gravity disturbance on the track using the extreme learning machine (ELM) method based on measured gravity data on the geoid and processes the gravity disturbance to the height where INS has an upward continuation, then compensates the obtained gravity disturbance into the error equations of INS to restrain the INS error propagation...
November 29, 2016: Sensors
https://www.readbyqxmd.com/read/27916237/transesophageal-speckle-tracking-echocardiography-improves-right-ventricular-systolic-function-assessment-in-the-perioperative-setting
#5
Nicholas W Markin, Mohammed Chamsi-Pasha, Jiangtao Luo, Walker R Thomas, Tara R Brakke, Thomas R Porter, Sasha K Shillcutt
BACKGROUND: Perioperative evaluation of right ventricular (RV) systolic function is important to follow intraoperative changes, but it is often not possible to assess with transthoracic echocardiographic (TTE) imaging, because of surgical field constraints. Echocardiographic RV quantification is most commonly performed using tricuspid annular plane systolic excursion (TAPSE), but it is not clear whether this method works with transesophageal echocardiographic (TEE) imaging. This study was performed to evaluate the relationship between TTE and TEE TAPSE distances measured with M-mode imaging and in comparison with speckle-tracking TTE and TEE measurements...
December 1, 2016: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/27915067/the-feasibility-and-effects-of-acupuncture-in-an-adolescent-nordic-ski-population
#6
Kristin L Garlanger, William H Fredericks, Alexander Do, Brent A Bauer, Edward R Laskowski
BACKGROUND: Studies investigating the use and effectiveness of acupuncture in adults post exercise have been well documented. Fewer studies involving acupuncture have been completed in the adolescent athlete population. To our knowledge there are no published studies that investigate the use of acupuncture in adolescent athletes within their field of play. OBJECTIVE: To primarily assess the feasibility of performing acupuncture in adolescent Nordic skiers within their athletic environment, and secondarily to measure the effect of acupuncture on muscle soreness and sense of well-being...
November 30, 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27913338/intracardiac-vortex-dynamics-by-high-frame-rate-doppler-vortography-i-in-vivo-i-comparison-with-vector-flow-mapping-and-4-d-flow-mri
#7
Julia Faurie, Mathilde Baudet, Kondo Claude Assi, Dominique Auger, Guillaume Gilbert, Francois Tournoux, Damien Garcia
Recent studies have suggested that intracardiac vortex flow imaging could be of clinical interest to early diagnose the diastolic heart function. Doppler vortography has been intro-duced as a simple color Doppler method to detect and quantify intraventricular vortices. This method is able to locate a vortex core based on the recognition of an antisymmetric pattern in the Doppler velocity field. Because the heart is a fast-moving organ, high frame rates are needed to decipher the whole blood vortex dynamics during diastole...
November 29, 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/27912066/cell-type-specific-optical-recording-of-membrane-voltage-dynamics-in-freely-moving-mice
#8
Jesse D Marshall, Jin Zhong Li, Yanping Zhang, Yiyang Gong, François St-Pierre, Michael Z Lin, Mark J Schnitzer
Electrophysiological field potential dynamics are of fundamental interest in basic and clinical neuroscience, but how specific cell types shape these dynamics in the live brain is poorly understood. To empower mechanistic studies, we created an optical technique, TEMPO, that records the aggregate trans-membrane voltage dynamics of genetically specified neurons in freely behaving mice. TEMPO has >10-fold greater sensitivity than prior fiber-optic techniques and attains the noise minimum set by quantum mechanical photon shot noise...
December 1, 2016: Cell
https://www.readbyqxmd.com/read/27910586/a-novel-method-to-recover-dd-fusion-proton-cr-39-data-corrupted-by-fast-ablator-ions-at-omega-and-the-national-ignition-facility
#9
G D Sutcliffe, L M Milanese, D Orozco, B Lahmann, M Gatu Johnson, F H Séguin, H Sio, J A Frenje, C K Li, R D Petrasso, H-S Park, J R Rygg, D T Casey, R Bionta, D P Turnbull, C M Huntington, J S Ross, A B Zylstra, M J Rosenberg, V Yu Glebov
CR-39 detectors are used routinely in inertial confinement fusion (ICF) experiments as a part of nuclear diagnostics. CR-39 is filtered to stop fast ablator ions which have been accelerated from an ICF implosion due to electric fields caused by laser-plasma interactions. In some experiments, the filtering is insufficient to block these ions and the fusion-product signal tracks are lost in the large background of accelerated ion tracks. A technique for recovering signal in these scenarios has been developed, tested, and implemented successfully...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910447/design-of-the-polar-neutron-imaging-aperture-for-use-at-the-national-ignition-facility
#10
V E Fatherley, D A Barker, D N Fittinghoff, R L Hibbard, J I Martinez, F E Merrill, J A Oertel, D W Schmidt, P L Volegov, C H Wilde
The installation of a neutron imaging diagnostic with a polar view at the National Ignition Facility (NIF) required design of a new aperture, an extended pinhole array (PHA). This PHA is different from the pinhole array for the existing equatorial system due to significant changes in the alignment and recording systems. The complex set of component requirements, as well as significant space constraints in its intended location, makes the design of this aperture challenging. In addition, lessons learned from development of prior apertures mandate careful aperture metrology prior to first use...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910384/dual-langmuir-probe-array-for-3d-plasma-studies-in-torpex
#11
M Baquero-Ruiz, F Avino, O Chellai, A Fasoli, I Furno, R Jacquier, F Manke, S Patrick
We have designed and installed a new Langmuir-probe (LP) array diagnostic to determine basic three-dimensional (3D) features of plasmas in TORPEX. The diagnostic consists of two identical LP arrays, placed on opposite sides of the apparatus, which provide comprehensive coverage of the poloidal cross section at the two different toroidal locations. Cross correlation studies of signals from the arrays provide a basic way to extract 3D information from the plasmas, as experiments show. Moreover, the remarkable signal-to-noise performance of the front-end electronics allows us to follow a different approach in which we combine information from all probes in both arrays to reconstruct elementary 3D plasma structures at each acquisition time step...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27909418/risk-and-ambiguity-in-information-seeking-eye-gaze-patterns-reveal-contextual-behavior-in-dealing-with-uncertainty
#12
Peter Wittek, Ying-Hsang Liu, Sándor Darányi, Tom Gedeon, Ik Soo Lim
Information foraging connects optimal foraging theory in ecology with how humans search for information. The theory suggests that, following an information scent, the information seeker must optimize the tradeoff between exploration by repeated steps in the search space vs. exploitation, using the resources encountered. We conjecture that this tradeoff characterizes how a user deals with uncertainty and its two aspects, risk and ambiguity in economic theory. Risk is related to the perceived quality of the actually visited patch of information, and can be reduced by exploiting and understanding the patch to a better extent...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27909262/overcoming-the-limits-of-evidence-on-effective-multisectoral-nutrition-policy
#13
Madhu Kumar Marasini, Ssansa Mugenyi
The multisectoral approach has evolved as a popular instrument to attain nutrition goals and targets. But as policy makers, we need timely, relevant, and accurate information in order to effectively support these plans. This commentary comes from the members of the nutrition secretariats at the National Planning Commission in Nepal and the Office of the Prime Minister in Uganda on availability and use of evidence and the nutrition policy cycle. As has been highlighted in this supplement, some of the challenges we have faced include tracking nutrition spending and limited human resource capacity...
December 2016: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/27906309/spiral-phase-mask-shadow-imaging-for-3d-measurement-of-flow-fields
#14
Martin Teich, Michael Mattern, Jeremy Sturm, Lars Büttner, Jürgen W Czarske
Particle tracking velocimetry (PTV) is a valuable tool for microfluidic analysis. Especially mixing processes and the environmental interaction of fluids on a microscopic scale are of particular importance for pharmaceutical and biomedical applications. However, currently applied techniques suffer from the lag of instantaneous depth information. Here we present a scan-free, shadow-imaging PTV-technique for 3D trajectory and velocity measurement of flow fields in micro-channels with 2 µm spatial resolution...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27904796/functional-hop-tests-and-tuck-jump-assessment-scores-between-female-division-i-collegiate-athletes-participating-in-high-versus-low-acl-injury-prone-sports-a-cross-sectional-analysis
#15
Philipp Hoog, Meghan Warren, Craig A Smith, Nicole J Chimera
BACKGROUND: Although functional tests including the single leg hop (SLH), triple hop (TH), cross over hop (COH) for distance, and the tuck jump assessment (TJA) are used for return to play (RTP) criteria for post anterior cruciate ligament (ACL) injury, sport-specific baseline measurements are limited. PURPOSE: The purpose of this study was to examine differences in SLH, TH, and COH distance and limb symmetry index (LSI), as well as total scores, number of jumps, and individual flaws of the TJA in 97 injury-free Division I (DI) collegiate female student athletes participating in ACL injury prone vs...
December 2016: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/27903729/joint-encoding-of-object-motion-and-motion-direction-in-the-salamander-retina
#16
Norma Krystyna Kühn, Tim Gollisch
: The processing of motion in visual scenes is important for detecting and tracking moving objects as well as for monitoring self-motion through the induced optic flow. Specialized neural circuits have been identified in the vertebrate retina for detecting motion direction or for distinguishing between object motion and self-motion, although little is known about how information about these distinct features of visual motion is combined. The salamander retina, which is a widely used model system for analyzing retinal function, contains object-motion-sensitive (OMS) ganglion cells, which strongly respond to local motion signals but are suppressed by global image motion...
November 30, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27901026/perceptual-training-yields-rapid-improvements-in-visually-impaired-youth
#17
Jeffrey B Nyquist, Joseph S Lappin, Ruyuan Zhang, Duje Tadin
Visual function demands coordinated responses to information over a wide field of view, involving both central and peripheral vision. Visually impaired individuals often seem to underutilize peripheral vision, even in absence of obvious peripheral deficits. Motivated by perceptual training studies with typically sighted adults, we examined the effectiveness of perceptual training in improving peripheral perception of visually impaired youth. Here, we evaluated the effectiveness of three training regimens: (1) an action video game, (2) a psychophysical task that combined attentional tracking with a spatially and temporally unpredictable motion discrimination task, and (3) a control video game...
November 30, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27898794/greenhouse-gas-emissions-from-solid-and-liquid-organic-fertilizers-applied-to-lettuce
#18
Phasita Toonsiri, Stephen J Del Grosso, Arina Sukor, Jessica G Davis
Improper application of nitrogen (N) fertilizer and environmental factors can cause the loss of nitrous oxide (NO) to the environment. Different types of fertilizers with different C/N ratios may have different effects on the environment. The focus of this study was to evaluate the effects of environmental factors and four organic fertilizers (feather meal, blood meal, fish emulsion, and cyano-fertilizer) applied at different rates (0, 28, 56, and 112 kg N ha) on NO emissions and to track CO emissions from a lettuce field ( L...
November 2016: Journal of Environmental Quality
https://www.readbyqxmd.com/read/27898029/data-driven-multiresolution-camera-using-the-foveal-adaptive-pyramid
#19
Martin González, Antonio Sánchez-Pedraza, Rebeca Marfil, Juan A Rodríguez, Antonio Bandera
There exist image processing applications, such as tracking or pattern recognition, that are not necessarily precise enough to maintain the same resolution across the whole image sensor. In fact, they must only keep it as high as possible in a relatively small region, but covering a wide field of view. This is the aim of foveal vision systems. Briefly, they propose to sense a large field of view at a spatially-variant resolution: one relatively small region, the fovea, is mapped at a high resolution, while the rest of the image is captured at a lower resolution...
November 26, 2016: Sensors
https://www.readbyqxmd.com/read/27897385/reconstruction-of-biological-pathways-and-metabolic-networks-from-in-silico-labeled-metabolites
#20
Noushin Hadadi, Jasmin Hafner, Keng Cher Soh, Vassily Hatzimanikatis
Reaction atom mappings track the positional changes of all of the atoms between the substrates and the products as they undergo the biochemical transformation. However, information on atom transitions in the context of metabolic pathways is not widely available in the literature. The understanding of metabolic pathways at the atomic level is of great importance as it can deconvolute the overlapping catabolic/anabolic pathways resulting in the observed metabolic phenotype. The automated identification of atom transitions within a metabolic network is a very challenging task since the degree of complexity of metabolic networks dramatically increases when we transit from metabolite-level studies to atom-level studies...
November 29, 2016: Biotechnology Journal
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