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https://www.readbyqxmd.com/read/29679757/molecular-characterization-of-cu-zn-sod-gene-in-asian-clam-corbicula-fluminea-and-mrna-expression-and-enzymatic-activity-modulation-induced-by-metals
#1
Xie Yanhai, Chen Hongbing, Zheng Shuangyan, Zhang Xiali, Mu Songniu
The copper/zinc superoxide dismutase (Cu/Zn SOD) could effectively eliminate reactive oxygen species (ROS). In this study, the cDNA sequence of Cu/Zn SOD from Corbicula fluminea (designated as CfCu/Zn SOD) was cloned by the rapid amplification of cDNA ends (RACE) approaches. The full-length cDNA of CfCu/Zn SOD was of 1288 bp, including a 465 bp ORF encoding a protein of 154 amino acids. Two SOD family signatures were identified in CfCu/Zn SOD amino acids sequence. Multiple sequence alignments indicated that CfCu/Zn SOD amino acid sequences exhibited high similarities to those of other species...
April 18, 2018: Gene
https://www.readbyqxmd.com/read/29679744/phylogenetic-relationships-within-the-opisthorchis-viverrini-species-complex-with-specific-analysis-of-o-viverrini-sensu-lato-from-sakon-nakhon-thailand-by-mitochondrial-and-nuclear-dna-sequencing
#2
Opal Pitaksakulrat, Bonnie L Webster, Joanne P Webster, Thewarach Laha, Weerachai Saijuntha, Poppy H L Lamberton, Nadda Kiatsopit, Ross H Andrews, Trevor N Petney, Paiboon Sithithaworn
The liver fluke Opisthorchis viverrini sensu lato causes serious public-health problems in northeast Thailand and Southeast Asian countries. A hypothesis has been proposed that O. viverrini represents a species complex with varying levels of genetic differentiation in Thailand and Lao PDR. This study aimed to clarify whether O. viverrini populations can be genetically divided into separate taxa. We collected O. viverrini s.l. from eight different locations in Lao PDR and Thailand. The results of nad1, cox1, CF-int6, Pm-int9, ITS2 and 28S rDNA sequence analysis revealed that sub-structuring occurred between the eight populations...
April 18, 2018: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/29679628/long-and-short-term-outcomes-of-gestational-diabetes-mellitus-gdm-among-south-asian-women-a-community-based-study
#3
REVIEW
B H Sudasinghe, C N Wijeyaratne, P S Ginige
AIMS: To quantify short and long-term outcomes of Gestational Diabetes Mellitus (GDM) among South Asians METHODS: Prospective cohort-study in Gampaha District, Sri Lanka following a community-prevalence study (WHO 1999 criteria). All women with GDM (exposed) and within sample non-GDM (non-exposed) were recruited. Data was gathered at selected intervals until one-year post-partum by interviewer-administered questionnaire, anthropometry, blood pressure, post-partum 75gOGTT and cholesterol...
April 18, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29679439/younger-age-and-language-barriers-are-associated-with-non-adherence-to-clinical-follow-up-in-hepatitis-b-treatment
#4
Heng Chi, Angie Japhary, Robert A de Man, Robert J de Knegt, Harry L A Janssen, Bettina E Hansen
We investigated the incidence and predictors of non-adherence towards clinic visits in chronic hepatitis B (CHB) patients on entecavir or tenofovir treatment. This was a retrospective study of CHB patients treated for at least 3 months in a tertiary referral hospital in The Netherlands. Lack of attendance in clinic visits was defined as a missed follow-up visit without notice. 338 patients (48% Caucasian, 37% Asian) were followed for a median of 3.5 years. During 1283 person-years, 183 scheduled follow-up visits were missed in 101 patients resulting in 0...
April 21, 2018: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/29679353/low-frequency-of-cervicocranial-artery-involvement-in-japanese-with-renal-artery-fibromuscular-dysplasia-compared-with-that-of-caucasians
#5
Eikan Mishima, Shu Umezawa, Takehiro Suzuki, Miki Fujimura, Michiaki Abe, Junichiro Hashimoto, Takaaki Abe, Sadayoshi Ito
BACKGROUND: Fibromuscular dysplasia (FMD), which usually affects the renal artery, also affects the carotid, vertebral, and intracranial arteries. Previous studies have shown a high prevalence of concomitant renal artery and cervicocranial lesions in FMD patients. However, the analyzed subjects were mostly Caucasians in Western countries. METHOD: We performed a retrospective analysis to examine the prevalence of cervicocranial vascular lesions in Japanese FMD patients with renal artery involvement at a single institution...
April 20, 2018: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/29679189/an-exploratory-study-of-spirituality-and-spiritual-care-among-malaysian-nurses
#6
Mohd Arif Atarhim, Susan Lee, Beverley Copnell
The increasing evidence that spirituality is a critical component for promoting health and well-being has made spirituality more significant to nursing practice. However, although nurses' perceptions of spirituality have been studied in western countries, there has been little research on this topic in Southeast Asian countries where religions other than Christianity predominate. This study explores Malaysian nurses' perceptions of spirituality and spiritual care and examines associations between socio-demographics and their perceptions...
April 20, 2018: Journal of Religion and Health
https://www.readbyqxmd.com/read/29679092/clinical-versus-echocardiographic-parameters-in-assessing-cardiac-resynchronisation-therapy-response-in-a-multiethnic-asian-population
#7
Chiw Yeh Lim, Kelvin Wong, Colin Yeo, Khim Leng Tong, Vern Hsen Tan
No abstract text is available yet for this article.
March 2018: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/29679087/optical-and-tectonic-corneal-transplant-outcomes-in-a-tertiary-hospital-in-singapore-within-the-singapore-corneal-transplant-registry
#8
Dawn Ho, Charmaine Chai, Hazel Lin, Hla Myint Htoon, Anna Marie Tan, Ray Manotosh, Donald Tan
INTRODUCTION: This study aimed to describe and compare corneal graft survival and optical outcomes following deep anterior lamellar keratoplasty (DALK) and Descemet's stripping automated endothelial keratoplasty (DSAEK) with penetrating keratoplasty (PK), and to document tectonic success of patch grafts. MATERIALS AND METHODS: This was a retrospective, non-randomised, comparative and descriptive cohort study. A total of 139 eyes that underwent primary keratoplasty between 2000 and 2016 were included, and the following data was extracted: demographics, clinical diagnosis and primary indication, pre- and intraoperative risk factors, postkeratoplasty outcomes, and complications...
March 2018: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/29679014/the-association-between-skin-auto-fluorescence-of-palmoplantar-sites-and-microvascular-complications-in-asian-patients-with-type-2-diabetes-mellitus
#9
Jong Jin Kim, Bosu Jeong, Yongin Cho, Mi-Hyang Kwon, Yong-Ho Lee, Uk Kang, Eun Seok Kang
Skin auto-fluorescence (SAF) has generated broad interest about the prospects for non-invasive advanced glycation end product assessment and its direct interplay with the development of microvascular complications, but clinical application of the existing SAF measuring of non-palmoplantar sites in non-Caucasian subjects with dark skin type is still controversial. Here, we tested the diabetic complication screening performance of a novel SAF measuring system in Asian type 2 diabetes mellitus (T2DM) subjects...
April 20, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29679005/late-miocene-climate-cooling-and-intensification-of-southeast-asian-winter-monsoon
#10
Ann E Holbourn, Wolfgang Kuhnt, Steven C Clemens, Karlos G D Kochhann, Janika Jöhnck, Julia Lübbers, Nils Andersen
The late Miocene offers the opportunity to assess the sensitivity of the Earth's climate to orbital forcing and to changing boundary conditions, such as ice volume and greenhouse gas concentrations, on a warmer-than-modern Earth. Here we investigate the relationships between low- and high-latitude climate variability in an extended succession from the subtropical northwestern Pacific Ocean. Our high-resolution benthic isotope record in combination with paired mixed layer isotope and Mg/Ca-derived temperature data reveal that a long-term cooling trend was synchronous with intensification of the Asian winter monsoon and strengthening of the biological pump from ~7 Ma until ~5...
April 20, 2018: Nature Communications
https://www.readbyqxmd.com/read/29678980/health-related-quality-of-life-in-asian-patients-with-breast-cancer-a-systematic-review
#11
Peh Joo Ho, Sofie A M Gernaat, Mikael Hartman, Helena M Verkooijen
OBJECTIVE: To summarise the evidence on determinants of health-related quality of life (HRQL) in Asian patients with breast cancer. DESIGN: Systematic review conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations and registered with PROSPERO (CRD42015032468). METHODS: According to the PRISMA guidelines, databases of MEDLINE (PubMed), Embase and PsycINFO were systematically searched using the following terms and synonyms: breast cancer, quality of life and Asia...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678852/whole-blood-pcr-for-rapid-screening-of-%C3%AE-0-thalassemia
#12
Phongsathorn Wichian, Supawadee Yamsri, Kanokwan Sanchaisuriya, Goonnapa Fucharoen, Supan Fucharoen
Hemoglobin Bart's hydrops fetalis (homozygous α0 -thalassemia) is the most severe form of thalassemia in the Southeast Asian population. Fetuses with this disorder almost always die in utero or shortly after birth. Screening of α0 -thalassemia carrier is therefore crucial. Currently, diagnosis of α0 -thalassemia genes is done by DNA-based analysis which relies on DNA extraction. We have developed a simple screening format based on whole blood PCR assay. The method was validated on 198 specimens and the results show 100% concordance with a conventional gap-PCR on DNA specimens...
March 2018: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/29678850/cryopreservation-of-genotyped-abo-subgroup-rbcs-for-quality-assurance-of-abo-grouping-reagents
#13
Sinyoung Kim, Sungwook Song, Hyun Ok Kim
BACKGROUND: Quality assurance of newly developed or manufactured blood grouping reagents with reagent red blood cells (RBCs) is crucial in the process of product approval by governmental agency. However, RBCs with rare blood group are not easily available in the fresh state. We investigated the feasibility of cryopreserved and genotyped ABO subgroup RBC reagents for quality assurance purpose. METHODS: We obtained RBCs from 10 volunteers with ABO subgroup phenotypes...
March 2018: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/29678635/high-incidence-of-occult-atrial-fibrillation-in-asian-patients-with-cryptogenic-stroke
#14
Swee-Chong Seow, Ann-Kee How, Siew-Pang Chan, Hock-Luen Teoh, Toon-Wei Lim, Devinder Singh, Wee-Tiong Yeo, Pipin Kojodjojo
BACKGROUND: Occult atrial fibrillation (AF) is not uncommon in patients with stroke. In western cohorts, insertable loop recorders (ILRs) have been shown to be the gold-standard and are cost-effective for AF detection. Anticoagulation for secondary stroke prevention is indicated if AF is detected. The incidence of occult AF among Asian patients with cryptogenic stroke is unclear. METHODS: Patients with cryptogenic stroke referred between August 2014 and February 2017 had ILRs implanted...
April 17, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29678513/review-of-blood-based-colorectal-cancer-screening-how-far-are-circulating-cell-free-dna-methylation-markers-from-clinical-implementation
#15
REVIEW
Mai-Britt Worm Ørntoft
Colorectal cancer (CRC) is a leading cause of cancer related deaths worldwide, and late stages (III-IV) in particular have low 5-year survival rates. Stage shifting by CRC screening programs has proven effective by decreasing morbidity and mortality and in many countries national CRC screening programs have been implemented. Currently, European, Asian, and American authorities recommend screening for CRC using fecal occult blood testing, sigmoidoscopy, or colonoscopy. Because these approaches all have weaknesses (eg, poor compliance, high costs, test invasiveness), much effort has been put into the development of alternative screening approaches, many of which are blood-based...
March 2, 2018: Clinical Colorectal Cancer
https://www.readbyqxmd.com/read/29678409/phototherapy-for-neonatal-hyperbilirubinemia-and-childhood-eczema-rhinitis-and-wheeze
#16
Elizabeth Huiwen Tham, Evelyn Xiu Ling Loo, Anne Goh, Oon Hoe Teoh, Fabian Yap, Kok Hian Tan, Keith M Godfrey, Hugo Van Bever, Bee Wah Lee, Yap Seng Chong, Lynette Pei-Chi Shek
BACKGROUND: The pathogenesis of allergic diseases in childhood may be attributed to influences of early environmental stimuli on fetal and neonatal immune regulation. Neonatal hyperbilirubinemia is common in the Asian population and up to 20% of infants require phototherapy. We examined the hypothesis that phototherapy for neonatal hyperbilirubinemia modulates the infant's risk of developing eczema, rhinitis and wheeze in the Growing Up in Singapore Towards healthy Outcomes (GUSTO) birth cohort...
March 24, 2018: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29678344/-variability-of-chloroquine-and-hydroxychloroquine-retinopathy-among-various-ethnicities
#17
A Giocanti-Aurégan, A Couturier, J-F Girmens, Y Le Mer, N Massamba, E Barreau, I Audo
INTRODUCTION: Current screening recommendations for chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy are based on central 10°C static perimetry and a high-resolution SD-OCT with a special attention to the inferior part of the macula where the toxicity usually starts by ellipsoid zone disruption. However, Melles and Marmor, have recently shown a great variability in the topography of the initial toxicity observed among various ethnicities, which is important to keep in mind so as not to miss early toxicity in certain subgroups of patients...
April 17, 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29678299/molecular-epidemiology-of-klebsiella-pneumoniae-k1-and-k2-isolates-in-japan
#18
Sohei Harada, Yoshikazu Ishii, Tomoo Saga, Kotaro Aoki, Kazuhiro Tateda
Although severe infections caused by hypervirulent Klebsiella pneumoniae isolates, such as K1 isolates belonging to sequence type (ST) 23, have been a significant problem in Asian countries, epidemiology of these isolates in Japan remains unclear. We performed a nationwide molecular epidemiological study of K. pneumoniae K1 and K2 isolates in Japan. Of the 259K. pneumoniae isolates collected, 14 and 16 isolates were identified as capsular genotypes K1 and K2, respectively. All K1 isolates were ST23 or its closely related clones and showed high genetic similarity by pulsed-field gel electrophoresis (PFGE) and the DiversiLab system (DL)...
March 20, 2018: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/29678270/multi-directional-reach-test-in-south-asian-children-normative-reference-scores-from-5-year-to-12-years-old
#19
Kavita Sharma, Asir John Samuel, Divya Midha, Vencita Priyanka Aranha, Kanimozhi Narkeesh, Narkeesh Arumugam
Multi-directional reach test (MRT) emerged as a valid and reliable assessment tool for balance evaluation among elderly. The normative reference scores have been established in adults and elderly people, but they were not yet established for children. Hence, we aimed at establishing the normative reference scores of MRT among the school going children aged between 5 and 12 years. Children (N = 194; 124 males, 70 females) were recruited by the stratified random sampling for the normative study. MRT was performed by the custom made, multi-directional reach estimator...
March 27, 2018: Homo: Internationale Zeitschrift Für die Vergleichende Forschung Am Menschen
https://www.readbyqxmd.com/read/29678168/self-competence-in-death-work-among-health-and-social-care-workers-a-region-wide-survey-in-hong-kong
#20
Johnny T K Cheung, Doreen W H Au, Wallace C H Chan, Jenny H Y Chan, Kenway Ng, Jean Woo
BACKGROUND: According to the Quality of Death Index, Hong Kong is lagging behind many other Western and Asian countries in the category of palliative and healthcare. To ensure the provision of high-quality palliative care, it is important to explore the self-competence of health and social care workers in coping with death work including palliative care. This region-wide study aims to assess the level of self-competence with a validated Self-Competence in Death Work Scale (SC-DWS) and examine its correlates...
April 20, 2018: BMC Palliative Care
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