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https://www.readbyqxmd.com/read/28638477/triptolide-inhibits-the-ar-signaling-pathway-to-suppress-the-proliferation-of-enzalutamide-resistant-prostate-cancer-cells
#1
Yangyang Han, Weiwei Huang, Jiakuan Liu, Dandan Liu, Yangyan Cui, Ruimin Huang, Jun Yan, Ming Lei
Enzalutamide is a second-generation androgen receptor (AR) antagonist for the treatment of metastatic castration-resistant prostate cancer (mCRPC). Unfortunately, AR dysfunction means that resistance to enzalutamide will eventually develop. Thus, novel agents are urgently needed to treat this devastating disease. Triptolide (TPL), a key active compound extracted from the Chinese herb Thunder God Vine (Tripterygium wilfordii Hook F.), possesses anti-cancer activity in human prostate cancer cells. However, the effects of TPL against CRPC cells and the underlying mechanism of any such effect are unknown...
2017: Theranostics
https://www.readbyqxmd.com/read/28634627/influence-of-multiple-stapler-firings-used-for-rectal-division-on-colorectal-anastomotic-leak-rate
#2
Tamara Braunschmid, Nikolaus Hartig, Lukas Baumann, Bernhard Dauser, Friedrich Herbst
BACKGROUND: Anastomotic leakage following colorectal resection remains one of the most significant complications with relevant morbidity and mortality. There is evidence that a higher number of stapler firings for rectal division can affect the leak rate in double stapling anastomosis. However, there are no data concerning compression anastomosis. We present our institutional experience addressing this issue. DESIGN: This is a retrospective review of a prospective institutional database of patients undergoing colonic and rectal resection for benign and malignant indications between January 2008 and December 2014 at the surgical department of the St...
June 20, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28630291/global-sustainable-development-priorities-500-y-after-luther-sola-schola-et-sanitate
#3
Wolfgang Lutz
Martin Luther succinctly summarized his theology in sola statements, such as sola scriptura, viewing the Bible (scriptura) as the only valid source of information about God rather than what he viewed as the extraneous, corrupting church doctrine of the time. As a secular side effect of this focus on individual reading skills, the Protestant territories were the first to acquire high literacy rates, which subsequently fostered health, economic growth, and good governance. Here I argue that a similar priority focus on empowerment of all segments of all populations through education and health (sola schola et sanitate) is needed today for sustainable development...
June 19, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28628378/knowledge-and-behavioral-impact-of-adult-participation-in-child-sexual-abuse-prevention-evaluation-of-the-protecting-god-s-children-program
#4
Anne M Nurse
This article presents findings from an evaluation of a popular adult training program (Protecting God's Children) used in Catholic institutions, including schools, churches, and social service agencies. The study explores knowledge and behavior change based on pretest/posttest questionnaires administered to over 500 adults and follow-up questionnaires sent six months after the training. The participants in the training were compared to a control group of adults who did not participate in the program. The results indicate that participants arrive at the training with fairly high rates of preexisting knowledge but that the program increases knowledge across demographic groups...
June 19, 2017: Journal of Child Sexual Abuse
https://www.readbyqxmd.com/read/28624983/how-to-increase-vaccination-acceptance-among-apostolic-communities-quantitative-results-from-an-assessment-in-three-provinces-in-zimbabwe
#5
Regina Gerede, Zorodzai Machekanyanga, Serigne Ndiaye, Kenneth Chindedza, Colline Chigodo, Messeret E Shibeshi, James Goodson, Fussum Daniel, Reinhard Kaiser
A worldwide increasing trend toward vaccine hesitancy has been reported. Measles outbreaks in southern Africa in 2009-2010 were linked to objections originating from Apostolic gatherings. Founded in Zimbabwe in the 1950s, the Apostolic church has built up a large number of followers with an estimated 3.5 million in Zimbabwe in 2014. To inform planning of interventions for the 2015 measles-rubella vaccination campaign, we assessed vaccination status and knowledge, attitudes and practices among purposive samples of Apostolic caregivers in three districts each in Harare City, Manicaland and Matabeleland South in Zimbabwe...
June 17, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28617735/evaluating-the-effectiveness-of-using-a-progressive-muscle-relaxation-technique-on-the-self-efficacy-of-breastfeeding-in-mothers-with-preterm-infants
#6
Soheila Karbandi, Seyedeh Maryam Hosseini, Seyedeh Asieh Hosseini, Farshad Sadeghi, Maryam Hesari, Reza Masoudi
BACKGROUND: Breast milk is a God-given gift that conveys a mother's love and compassion and that is made according to the needs and age of the child. Mothers who are interested in the welfare of their newborns tend to breastfeed their children. Training programs have been shown to improve breastfeeding self-efficacy in terms of both duration and amount. PURPOSE: The aim of this study was to evaluate the effect of using the progressive muscle relaxation (PMR) technique on the self-efficacy of breastfeeding in mothers with preterm infants...
June 14, 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/28604521/spiritual-reflection-inviting-god-into-our-moments
#7
Carrie M Dameron
No abstract text is available yet for this article.
July 2017: Journal of Christian Nursing: a Quarterly Publication of Nurses Christian Fellowship
https://www.readbyqxmd.com/read/28596323/saving-the-god-of-ugly-things
#8
Elizabeth Pennisi
No abstract text is available yet for this article.
June 9, 2017: Science
https://www.readbyqxmd.com/read/28591375/-barriers-to-the-search-for-female-sterilization-among-women-in-the-bolsa-fam%C3%A3-lia-program
#9
Marion Teodósio de Quadros, Giselle Maria Nanes Correia Dos Santos
Poor women in the Bolsa Família program are accused of having more children in order to enroll or remain in the program. In an ethnographic study (2012-2014), we analyzed reports by five beneficiaries of the program and found exactly the opposite. The women reported that they had gone to public health services in Recife, Pernambuco State, Brazil, in hopes of avoiding more children, but that they had encountered various obstacles. Such barriers included difficulties in obtaining reversible contraception and restrictions in the supply of sterilization in these services, which increases the demand for cesarean sections...
June 1, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28588957/spiritual-issues-of-people-living-and-dying-with-advanced-heart-failure-in-kenya-a-qualitative-serial-interview-study
#10
Kellen N Kimani, Scott A Murray, Liz Grant
BACKGROUND: Exploring patients' spiritual issues is vital for informing holistic care. The spiritual concerns of patients living and dying with advanced heart failure in sub-Saharan Africa remains unknown. Our aim was to describe spiritual issues in the context of the lived experiences of patients with heart failure in Kenya. METHODS: We purposively recruited 18 patients admitted with advanced heart failure at a rural district hospital in Kenya. We conducted serial in-depth interviews with patients at 0, 3 and 6 months after recruitment...
November 2016: BMJ Global Health
https://www.readbyqxmd.com/read/28585974/roles-of-nitrogen-functionalities-in-enhancing-the-excitation-independent-green-color-photoluminescence-of-graphene-oxide-dots
#11
Chiao-Yi Teng, Ba-Son Nguyen, Te-Fu Yeh, Yuh-Lang Lee, Shean-Jen Chen, Hsisheng Teng
Fluorescent graphene oxide dots (GODs) are environmentally friendly and biocompatible materials for photoluminescence (PL) applications. In this study, we employed annealing and hydrothermal ammonia treatments at 500 and 140 °C, respectively, to introduce nitrogen functionalities into GODs for enhancing their green-color PL emissions. The hydrothermal treatment preferentially produces pyridinic and amino groups, whereas the annealing treatment produces pyrrolic and amide groups. The hydrothermally treated GODs (A-GODs) present a high conjugation of the nonbonding electrons of nitrogen in pyridinic and amino groups with the aromatic π orbital...
June 6, 2017: Nanoscale
https://www.readbyqxmd.com/read/28584543/comparing-the-concept-of-caring-in-islamic-perspective-with-watson-and-parse-s-nursing-theories
#12
Akram-Sadat Sadat-Hoseini, Abdoul-Hosein Khosropanah
BACKGROUND: In the nursing profession, it is apparent that the definition of caring differs between various perspectives. This article compares the difference of caring in Islamic with the Parse and Watson theories. MATERIALS AND METHODS: In this study, we use concept analyses of Walker-Avants and compare research methods. Material used is all Islamic documents. RESULTS: According to Islamic documents, there are four major types of caring, namely, (1) God taking care of humans, (2) Humans taking care of themselves, (3) Other humans taking care of humans, and (4) The universe taking care of humans and vice versa...
March 2017: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/28582709/electrodepositable-alginate-membranes-for-enzymatic-sensors-an-amperometric-glucose-biosensor-for-whole-blood-analysis
#13
A Márquez, C Jiménez-Jorquera, C Domínguez, X Muñoz-Berbel
Simple and disposable point of care systems are usually the best solution for chronic patients to get a rapid diagnosis in home care context. However, their main drawback relies on the poor reliability derived from the low stability of the bio-recognition elements and low quality of the transducers. In the current work, we study the use of electrodeposited calcium alginate hydrogels as a biocompatible matrix in the development of enzymatic amperometric biosensors for whole blood analysis, to enhance the enzymes stability and to protect the transducer from biofouling...
May 30, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28578682/secondary-distress-in-violence-researchers-a-randomised-trial-of-the-effectiveness-of-group-debriefings
#14
Heidi Grundlingh, Louise Knight, Dipak Naker, Karen Devries
BACKGROUND: Secondary distress including emotional distress, vicarious trauma (VT) and secondary traumatic stress (STS) due to exposure to primary trauma victims have been described in helping professionals and in violence researchers. To our knowledge, there are few prevalence studies, and no tailored interventions have been tested to reduce secondary distress in violence researchers. The study aims to (1) describe the epidemiology of secondary distress experienced by violence researchers; to (2) assess the effectiveness of group debriefings in mitigating secondary distress; to (3) assess risk and protective factors...
June 2, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28565922/god-heresy-trials-and-psychiatry
#15
Doug Sellman
No abstract text is available yet for this article.
May 1, 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/28560488/lived-religion-as-reproductive-decision-making-resource-among-romanian-women-who-use-abortion-as-contraception
#16
Cristina A Pop
This article draws upon qualitative ethnographic data collected between 2005 and 2013 in southern Romania among women who have been consistently using abortion as a contraceptive method. It particularly considers the role that lived religion might have played in some individuals' strategies to render abortion a justifiable practice. Over the last seven decades, Romanian women's experiences of abortion have often been at odds with both secular and religious regulations. This study shifts the perspective from the biopolitics and the bioethics of abortion toward women's own reproductive decision-making strategies in a context of enduring traditional patriarchy...
May 30, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28553805/prayer-attachment-to-god-and-changes-in-psychological-well-being-in-later-life
#17
Matt Bradshaw, Blake Victor Kent
OBJECTIVE: The aim of this study was to investigate the effects of prayer and attachment to God on psychological well-being (PWB) in later life. METHOD: Using data from two waves of the nationwide Religion, Aging, and Health Survey, we estimate the associations between frequency of prayer and attachment to God at baseline with cross-wave changes in three measures of PWB: self-esteem, optimism, and life satisfaction. RESULTS: Prayer does not have a main effect on PWB...
January 1, 2017: Journal of Aging and Health
https://www.readbyqxmd.com/read/28553604/diabetes-care-inspiration-from-sikhism
#18
REVIEW
Gagan Priya, Sanjay Kalra, Inderpreet Kaur Dardi, Simarjeet Saini, Sameer Aggarwal, Ramanbir Singh, Harpreet Kaur, Gurinder Singh, Vipin Talwar, Parminder Singh, Brig J S Saini, Sandeep Julka, Rajeev Chawla, Sarita Bajaj, Devinder Singh
Religion has been proposed as a means of enhancing patient and community acceptance of diabetes and cultural specific motivational strategies to improve diabetes care. Sikhism is a young and vibrant religion, spread across the world and the Holy Scripture Sri Guru Granth Sahib (SGGS) is regarded as the living Guru by all Sikhs. The three key pillars of Sikhism are Kirat Karni (honest living), Vand Chakna (sharing with others) and Naam Japna (focus on God). They can help encourage the diabetes care provider, patient and community to engage in lifestyle modification, shared responsibility, positive thinking and stress management...
May 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28552309/zymographic-approach-to-determine-the-intrinsic-enzyme-specific-activity-of-diamine-oxidase-in-presence-of-interfering-enzymes
#19
Samaneh Ahmadifar, Tien Canh Le, Lucia Marcocci, Paola Pietrangeli, Mircea Alexandru Mateescu
The purpose of this investigation was to elaborate a fast zymographic assay of oxidase enzymes in the presence of interfering enzymes as catalase (which disturbs current dosages based on H2O2 detection). This method also allows the determination of intrinsic specific activity (ISA) of oxidases, such as diamine oxidase (DAO) or glucose oxidase (GOD). The SDS-PAGE gels with entrapped peroxidase have been obtained by polymerization of acrylamide and bis-acrylamide in the presence of horse-radish peroxidase. The entrapped peroxidase was uniformly distributed in the PolyacrylAmide (PAA) material and did not migrate during electrophoresis...
July 4, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28551122/a-recyclable-silver-ions-specific-surface-enhanced-raman-scattering-sers-sensor
#20
Dan Sun, Guohua Qi, Fanghao Cao, Weiqing Xu, Qidan Chen, Shuping Xu
A highly sensitive and recyclable surface-enhanced Raman scattering (SERS) chip sensor is designed for the determination of silver ions. It is based on the specific reversible binding between silver ions and glucose oxidase (GOD). The sensing chip is made by layer-by-layer assembling GOD on a metal nanoparticle-assembled, SERS-active chip with a positive charged polyelectrolyte as a linker. Iso-alloxazine, a chromophore in flavin adenine dinucleotide (FAD) in GOD, coordinates with silver ions, which causes significant variation in SERS spectra of GOD...
August 15, 2017: Talanta
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