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Rosai dorfman

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https://www.readbyqxmd.com/read/29455179/a-quintessential-syndrome-with-a-rare-marvelling-aetiology-rosai-dorfman-disease-presenting-as-conus-cauda-syndrome
#1
Bharath A Chhabria, Ram V Nampoothiri, Kaniyappan Nambiyar, Deepesh Lad
A 19-year-old woman presented with a history of severe lower backache and asymmetric proximal lower limb weakness during the past 3 months. In addition, she also suffered from lower motor neuron-type bladder and bowel symptoms. On examination, paraparesis was noted. Further, sensory examination suggested patchy asymmetric sensory loss in both lower limbs with saddle anaesthesia and areflexia. A clinical diagnosis of Conus-Cauda syndrome was made and contrast-enhanced MRI of the lumbar and sacral spine was done, which confirmed the presence of a mass lesion within the spinal canal involving the cauda equina extending up to the sacral level...
February 17, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29451149/a-study-on-clinical-characteristics-and-magnetic-resonance-imaging-manifestations-on-systemic-rosai-dorfman-disease
#2
Xiao Cheng, Jing-Liang Cheng, An-Kang Gao
Background: Rosai-Dorfman disease (RDD) is typically characterized by painless bilateral and symmetrical cervical lymphadenopathy, with associated fever and leukocytosis. The aim of the current study was to summarize the clinical features and imaging characteristics of RDD, in an effort to improve its diagnostic accuracy. Methods: The study was analyzed from 32 patients between January 2011 and December 2017; of these, 16 patients had pathologically diagnosed RDD, eight had pathologically diagnosed meningioma, and eight pathologically diagnosed lymphoma...
February 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29435284/18f-fluoro-2-deoxyglucose-positron-emission-computed-tomography-in-a-rare-cutaneous-form-of-rosai-dorfman-disease-a-case-report
#3
Joya Hadchiti, Francois G Kamar, Jean Abi Ghosn, Mohamad Haidar, Ahmad Younes, Antoine Obeid, Marwan Haddad, Fadi Farhat, Feras Chehade
Rosai-Dorfman disease (RDD), or sinus histiocytosis with massive lymphadenopathy, commonly involves the lymph nodes but may secondarily involve the skin. Purely cutaneous disease without lymphatics or internal organ involvement occurs rarely. The present report detailed a rare case of 18F-fluoro-2-deoxyglucose positron emission-computed tomography (18FDG PET-CT) performed in a 33-year-old male soldier with a purely cutaneous form of RDD. Staging with 18FDG PET-CT was ordered prior to excisional biopsies of the aforedescribed masses and pathology reported RDD...
February 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29428455/ophthalmic-findings-of-rosai-dorfman-disease
#4
Michael B Choi, Diva R Salomão, Wendy M Smith, Jose S Pulido, James A Garrity
PURPOSE: To describe the ophthalmic, pathologic, and BRAF V600E mutation status of Rosai-Dorfman Disease (RDD). DESIGN: Retrospective case series. METHODS: A retrospective review of all cases of RDD seen at Mayo Clinic from 1992 to 2016 identified patients with ophthalmic manifestations (n=8). Immunostain for BRAF and molecular studies for BRAFV600E mutation were performed on cases with tissue available. RESULTS: Of 76 patients with RDD, 15 had eye exams and, of those, 8 had ophthalmic manifestations (5 females and 3 males)...
February 8, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29405342/melanoma-mimicking-rosai-dorfman-disease
#5
D Y Xie, C M Costello, H J Liang, B G Thomas, D J DiCaudo, A R Mangold
Despite advances in treatment and increased public awareness, the incidence of melanoma has dramatically increased over the last 50 years 1,2 . Primary and secondary prevention is critical for decreasing the incidence and improving outcomes in melanoma3 . A proper clinical and histopathological diagnosis is necessary for definitive management.
February 5, 2018: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/29400286/cutaneous-rosai-dorfman-disease-of-the-face-with-a-leonine-appearance-successful-response-to-dapsone
#6
Young In Lee, Sang Kyum Kim, Sang Ho Oh, Do Young Kim
No abstract text is available yet for this article.
February 5, 2018: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/29390533/multimodality-imaging-based-evaluation-of-rosai-dorfman-disease-in-the-head-and-neck-a-retrospective-observational-study
#7
Qinggang Xu, Liping Fu, Chengyao Liu
Rosai-Dorfman disease (RDD) is an uncommon benign entity characterized histologically by lymphatic sinus dilatation due to histiocyte proliferation. This study was performed to delineate its imaging features, reviewed retrospectively in 12 patients (8 women and 4 men, mean age 58.2 years [range 27-84]) with pathologically confirmed RDD in the head and neck. The location, involvement, and imaging characteristics (CT, magnetic resonance imaging (MRI), and PET/CT) of all lesions were evaluated. Signal intensity on MRI images was compared to gray matter (orbital RDD) and adjacent muscle (sinonasal and cervical RDD)...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29381971/isolated-intracranial-rosai-dorfman-disease-mimicking-petroclival-meningioma-in-a-child-case-report-and-review-of-the-literature
#8
Xiang Yang, Jiagang Liu, Yanming Ren, Seidu A Richard, Yuekang Zhang
RATIONALE: Rosai -Dorfman disease (RDD) is a rare, idiopathic, and non-neoplastic histioproliferative disease with distinctive entity of unknown etiology. Central nervous system (CNS) RDD is uncommon, hence, isolated intracranial RDD is extremely rare. So far only 6 cases of CNS RDD with the lesions originating from petroclival region have been reported. We present a case of isolated intracranial RDD mimicking petroclival meningioma. PATIENT CONCERNS: A 14-year-old girl was admitted at our hospital with a 3-month history of dizziness, slowly progressing headache, and 2-month history of instability in walking...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29372088/soft-tissue-rosai-dorfman-disease-case-report
#9
Rubyath C Rajib, Rajasekharan Pillai, Ibrahim A Sulaiman, Ibrahim Al-Haddabi
Rosai-Dorfman disease (RDD) is a rare benign proliferative histiocytic disorder characterised by massive lymphadenopathy. While extranodal involvement can occur in generalised RDD, isolated soft tissue RDD (STRDD) is extremely rare. We report a 17-year-old male patient who presented to the maxillofacial outpatient department of the Sultan Qaboos Hospital, Salalah, Oman, in 2015 with a painless cheek mass which had been slowly growing over the previous two months. Routine histopathological examinations and immunohistochemistry confirmed a diagnosis of STRDD...
November 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29341328/histiocytosis-cutaneous-manifestations-of-hematopoietic-neoplasm-and-non-neoplastic-histiocytic-proliferations
#10
REVIEW
C M Luder, T M Nordmann, E Ramelyte, B Mühleisen, K Kerl, O Boyman, E Guenova, R Dummer
Histiocytoses are rare disorders characterized by the accumulation of cells derived from macrophages, dendritic cells, or monocytes in various tissues. There is a broad spectrum of disease manifestations with some subtypes commonly showing skin lesions while in others the skin is rarely involved. Here we describe cutaneous manifestations of histiocytoses belonging to the Langerhans group (L group), the group of cutaneous and mucocutaneous histiocytoses (C group) and the group of Rosai-Dorfman disease and related histiocytoses (R group) according to the current classification...
January 16, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29332707/cutaneous-hemophagocytosis-clinicopathologic-features-of-21-cases
#11
Francesca Boggio, Viviana Lora, Carlo Cota, Amanda Pereira, Robert Müllegger, Lucia Prieto-Torres, Lorenzo Cerroni
BACKGROUND: Hemophagocytosis is well known in cytotoxic cutaneous T-cell lymphomas (CTCLs), in which it may represent a sign of hemophagocytic lymphohistiocytosis syndrome (HLHS), and is also typical of cutaneous Rosai-Dorfman disease (cRDD) (without prognostic relevance). Only rarely, has cutaneous hemophagocytosis (CH) been described in other skin conditions. OBJECTIVE: To characterize the clinicopathologic features of CH in skin biopsy specimens from patients with conditions other than CTCL or cRDD...
February 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29319260/rosai-dorfman-disease
#12
B N Mahanta, T Goswami Mahanta
A young male presented with recurrent neck swellings with initial leucocyte count of 16800/mm3, with non-caseating glands on ultrasonography neck. FNAC showed mixed cellularity with histiocytic and marked lymphophagocytosis as seen in Rosai Dorfman Disease. Immunohistochemistry demonstrated CD 25, Ki 67 and CD 68 in histiocytes. Her responded to supportive treatment alone.
October 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29313941/image-gallery-metachronic-occurrence-of-primary-cutaneous-marginal-zone-b-cell-lymphoma-and-primary-cutaneous-rosai-dorfman-disease-in-the-same-patient
#13
A González-Quesada, J Bastida, J C Rivero-Vera, M A Piris-Pinilla, M A Limeres-González
No abstract text is available yet for this article.
December 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/29288039/immunoglobulin-g4-related-chronic-rhinosinusitis-a-pitfall-in-the-differential-diagnosis-of-granulomatosis-with-polyangiitis-rosai-dorfman-disease-and-fungal-rhinosinusitis
#14
Yingshi Piao, Yuan Zhang, Changli Yue, Chengshuo Wang, Luo Zhang
Immunoglobulin G4 (IgG4)-related chronic rhinosinusitis (CRS) has recently been proposed to be a new clinical entity of nasal disease, with no consensually agreed criteria for diagnosis. Moreover, the pathological features if IgG4-related CRS often overlap with other sinonasal inflammatory and autoimmune diseases such as Granulomatosis with Polyangiitis (GPA), Rosai-Dorfman disease (RDD) and Fungal Rhinosinusitis (FRS). We aimed to explore the specific similarities and differences in clinicopathologic features between IgG4-related CRS, and GPA, RDD and FRS, in order that these conditions can be diagnosed more accurately...
December 26, 2017: Human Pathology
https://www.readbyqxmd.com/read/29285599/computed-tomography-and-magnetic-resonance-imaging-of-peripelvic-and-periureteric-pathologies
#15
REVIEW
Ekim Gumeler, Mehmet Ruhi Onur, Ali Devrim Karaosmanoglu, Mustafa Ozmen, Deniz Akata, Musturay Karcaaltincaba
Peripelvic and periureteric areas are frequently overlooked in the imaging evaluations of the urinary system on computed tomography and magnetic resonance imaging. Several neoplastic and non-neoplastic disorders and diseases including lipomatosis, angiomyolipoma and angiolipomatous proliferation, vascular lesions, lymphangiomatosis, Rosai-Dorfman disease, Erdheim-Chester disease, extramedullary hematopoiesis, IgG4-related disease, lymphoma, mesenchymal tumors, trauma, and Antopol-Goldman lesion may involve these areas...
December 28, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29233361/bronchial-involvement-in-rosai-dorfman-disease
#16
Yurdagül Uzunhan, Alexandre Chabrol, Marianne Kambouchner, Emmanuel Martinod
No abstract text is available yet for this article.
January 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29224419/expanding-the-phenotype-of-alk-positive-histiocytosis-a-report-of-2-cases
#17
Huiya Huang, Gabriela Gheorghe, Paula E North, Mariko Suchi
ALK-positive histiocytosis is a recently described rare histiocytic proliferative disorder of early infancy. When infants present with anemia, thrombocytopenia, and hepatosplenomegaly, this entity should be included in the differential diagnosis along with hemophagocytic lymphohistiocytosis, metabolic/storage diseases, hematopoietic malignancies, and autoimmune thrombocytopenia. We report 2 new cases of ALK-positive histiocytosis, one with kidney involvement and the other with extensive bone marrow involvement in addition to an overt liver disease...
January 1, 2017: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/29217303/castleman-disease-and-rosai-dorfman-disease
#18
REVIEW
Miguel A Piris, Elena Aguirregoicoa, Santiago Montes-Moreno, Catuxa Celeiro-Muñoz
This chapter describes the main features of two different diseases, Castleman Disease (CD) and Rosai-Dorfman Disease (RDD). Castleman disease (CD) is a clinical and histopathologically heterogeneous lymphoproliferative disorder that encompasses at least three distinct entities with some common overlapping morphological features: Hyaline Vascular CD (HVCD), Unicentric Plasma Cell CD and Multicentric CD. The most important feature of HVCD is the presence of abnormal germinal centers with hyaline-vascular transformation, sometimes showing multiple germinal centers within a single reactive lymphoid follicle, this outlining HVCD as a disorder of follicular dendritic cells...
December 2, 2017: Seminars in Diagnostic Pathology
https://www.readbyqxmd.com/read/29215410/isolated-multinodular-soft-tissue-rosai-dorfman-disease-on-fdg-pet-ct
#19
Darko Pucar, William B Laskin, Lawrence Saperstein
Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy) is a rare systemic histiocytic disorder of unknown etiology characterized by the accumulation of enlarged non-Langerhans histiocytes within lymph nodes and extranodal sites. The histiocytes display characteristic emperipolesis (nondestructive engulfment of inflammatory cells) and are CD68 and S100 positive and CD1a negative. Although extranodal disease frequently occurs with nodal involvement, isolated extranodal disease is uncommon. We report a case of isolated localized subcutaneous multinodular disease on FDG PET/CT...
December 5, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29200169/sinus-histiocytosis-with-massive-lymphadenopathy-rosai-dorfman-disease-diagnostic-and-treatment-modalities-for-this-rare-entity-revisited
#20
Andrew W Averitt, Kenneth Heym, Lauren Akers, Fernando Castro-Silva, Anish Ray
Rosai-Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy is a rare non-Langerhans' cell histiocytic disease resulting from the proliferation and accumulation of sinus histiocytes within lymph nodes. Extranodal involvement frequently occurs, which increases the morbidity and mortality of the disease. There is no clear consensus with regard to the most effective diagnostic and treatment modalities. This report will focus on the diagnostic imaging, treatment, and outcomes for 3 cases of Rosai-Dorfman disease...
December 1, 2017: Journal of Pediatric Hematology/oncology
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