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Rosai dorfman

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https://www.readbyqxmd.com/read/28532172/cranio-spinal-rosai-dorfman-disease-case-series-and-literature-review
#1
Shashank S Joshi, Shilpa Joshi, Girish Muzumdar, Keki E Turel, Rajan M Shah, Indoo Ammbulkar, Muhammad Masood Hussain, Kishor A Choudhari
Rosai-Dorfman disease (RDD) is a rare condition similar to lymphomas, presenting with cervical lymphadenopathy in young adults. Extra-nodal involvement is relatively common but involvement of the central nervous system (CNS) is rare. Cranial RDD presents with symptoms of raised intracranial pressure, focal or generalised seizures, while spinal RDD presents with pain, peripheral neurological deficits and radiculopathy. In contrast to other similar neoplastic or degenerative conditions affecting the CNS, RDD is a benign, non-infective, granulomatous disorder...
May 22, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/28525449/spontaneous-recovery-of-rosai-dorfman-disease-on-fdg-pet-ct
#2
Qianqian Xue, Weibing Miao
Rosai-Dorfman disease is a rare systemic proliferative disorder of histiocytes, which mainly manifests as lymphadenopathy but also often involves extranodal tissues. Rosai-Dorfman disease was often self-limited. We hereby report a case of Rosai-Dorfman disease involving both the lymph nodes and the lungs, which was spontaneously resolved on FDG PET/CT.
May 19, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28503389/rosai-dorfman-disease-of-the-breast
#3
Eileen E Delaney, Anne Larkin, Sue MacMaster, Ali Sakhdari, Carolynn M DeBenedectis
Rosai-Dorfman disease (also known as sinus histiocytosis with massive lymphadenopathy) is a rare benign proliferative disorder of histiocytes that typically involves the lymph nodes and can also involve extranodal sites. Rosai-Dorfman disease confined to the breast is extremely rare, but important to recognize as it can mimic malignancy. We present the case of a 63-year-old woman who presented with a palpable breast lump that was highly suspicious for malignancy based on mammogram and ultrasound appearance...
April 11, 2017: Curēus
https://www.readbyqxmd.com/read/28500693/the-clinical-spectrum-of-xanthomatous-lesions-of-the-eyelids
#4
REVIEW
Can Baykal, Algun Polat Ekinci, Kurtulus D Yazganoglu, Nesimi Buyukbabani
Yellowish papules, nodules, or plaques, namely "xanthomatous" lesions, may be seen on the eyelids in the course of various disorders. The prototype is "xanthelasma palpebrarum" (XP) that is localized only to the eyelids and may be associated with hyperlipidemia. On the other hand, different types of normolipemic disorders may also cause xanthomatous eyelid lesions. Among these, Langerhans cell histiocytosis, diffuse normolipemic xanthoma, and non-Langerhans cell histiocytoses (papular xanthoma, juvenile xanthogranuloma, xanthoma disseminatum, adult-onset xanthogranuloma, adult-onset asthma and periocular xanthogranuloma, necrobiotic xanthogranuloma, Erdheim-Chester disease, Rosai-Dorfman disease, and reticulohistiocytosis) can be listed...
May 13, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28443319/multifocal-rosai-dorfman-disease-with-involvement-of-the-pinna
#5
Molly B Hirt, Jordan Heskett, Vindhya Veerula, Simon Warren, Nidhi Avashia-Khemka, Lawrence A Mark
No abstract text is available yet for this article.
May 2017: JAAD Case Reports
https://www.readbyqxmd.com/read/28431722/rosai-dorfman-disease-of-right-atrium-mimicking-myxoma
#6
Surendra Nath Khanna, Krishna Subramony Iyer, Mathews Paul, S Radhakrishnan, Arun K Rathi
Rosai-Dorfman disease, or sinus histiocytosis with massive lymphadenopathy, is a rare multisystemic disorder that was first reported by Rosai and Dorfman in 1969. It is a distinct histioproliferative disorder due to overproduction of histiocytes, which accumulate in lymph nodes. The cardiac involvement of this disease is extremely rare, and until now, only 18 cases have been reported. We report the case of a 53-year-old woman with right atrial mass mimicking myxoma, which the histopathologic evaluation revealed to be Rosai-Dorfman disease of the right atrium...
May 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28420843/rosai-dorfman-disease-of-the-lung-overlapping-with-igg4-related-disease-the-difficulty-in-its-differential-diagnosis
#7
Mizue Hasegawa, Fumikazu Sakai, Asako Okabayashi, Hideki Katsura, Toshiko Kamata, Eitetsu Koh, Yasuo Sekine, Tamiko Takemura, Yukio Nakatani, Kenzo Hiroshima
We herein report a case of Rosai-Dorfman disease (RDD) overlapping with IgG4-related disease (IgG4-RD), which presented as diffuse interstitial lung disease with a perilymphatic pattern, followed by submandibular gland and eyelid swelling. The pathological findings of the submandibular gland biopsy specimen were indicative of IgG4-RD alone. We diagnosed the patient with RDD with overlapping IgG4-RD. However, the optimal method for differentiating between these two entities is still controversial. It is important that clinicians are aware that RDD should be included in the differential diagnoses of diffuse interstitial lung disease with a perilymphatic pattern and that RDD can overlap with IgG4-RD...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28403515/an-aggressive-multifocal-primary-cns-histiocytosis-with-ptpn11-shp2-mutation
#8
Qi Zhang, Areej Shibani, Bekim Sadikovic, Christopher J Howlett, Lee-Cyn Ang
Primary histiocytic tumors of the CNS are rare. The current WHO classification (2016) included 5 entities: Langerhans cell histiocytosis (LCH), Erdheim-Chester disease (ECD), Rosai-Dorfman disease (RDD), juvenile xanthogranuloma (JXG), and histiocytic sarcoma (HS) (1). The diagnosis usually is made based on the tumor differentiation as to the counterpart in normal histiocyte development. This article is protected by copyright. All rights reserved.
April 12, 2017: Neuropathology and Applied Neurobiology
https://www.readbyqxmd.com/read/28401384/bone-involvement-in-rosai-dorfman-disease-rdd-a-case-report-and-systematic-literature-review
#9
REVIEW
Birgit A Mosheimer, Bastian Oppl, Shahin Zandieh, Michael Fillitz, Felix Keil, Klaus Klaushofer, Günter Weiss, Jochen Zwerina
PURPOSE OF REVIEW: Rosai-Dorfman disease (RDD) is a rare histiocytic disorder typically presenting as painless cervical lymphadenopathy. Extranodal involvement is common and may also affect bones. Here, we present a patient with typical nodal disease and multifocal bone manifestations. Further, a systematic literature review was performed to better understand the phenotype, clinical course and treatment options of such patients. RECENT FINDINGS: RDD is a nonmalignant, classically sporadic histiocytosis...
May 2017: Current Rheumatology Reports
https://www.readbyqxmd.com/read/28396615/bone-pathologic-fracture-revealing-an-unusual-association-coexistence-of-langerhans-cell-histiocytosis-with-rosai-dorfman-disease
#10
Boubacar Efared, Asmae Mazti, Badarou Chaibou, Gabrielle Atsame-Ebang, Ibrahim Sory Sidibé, Layla Tahiri, Fatimazahra Erregad, Nawal Hammas, Abdelmajid El Mrini, Hinde El Fatemi, Laila Chbani
BACKGROUND: The coexistence of Rosai-Dorfman disease (RDD) with Langerhans cell histiocytosis (LCH) is very rare, as to date only 17 cases have been reported in the english literature. The pathophysiology of this uncommon co-occurrence still remains enigmatic and a subject of various speculations. CASE PRESENTATION: We report a case of a 30-year-old female patient who presented with a pathologic fracture of the left proximal femur. Her medical history was unremarkable, there were no fever, skin lesions, lymphadenopathy or other organomegaly at physical examination...
2017: BMC Clinical Pathology
https://www.readbyqxmd.com/read/28377039/novel-presentation-of-rosai-dorfman-histiocytosis-with-a-prolonged-course-of-cranial-and-peripheral-neuropathies
#11
Richa Tripathi, Fatema Serajee, Huiyuan Jiang, A H M Mahbubul Huq
BACKGROUND: Rosai-Dorfman disease is a form of histiocytosis affecting the systemic lymph nodes. Intracranial Rosai-Dorfman disease is rare and presents with extra-parenchymal or intraparenchymal proliferative mass lesions. Cranial neuropathy has not been reported in Rosai-Dorfman disease except when caused by mass effect by an adjacent lesion. PATIENT DESCRIPTION: We describe a girl with Rosai-Dorfman disease who presented with peripheral and multiple cranial neuropathies...
March 8, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28376596/-rosai-dorfman-disease-of-shin-bone-report-of-a-case
#12
Q Y Yang, Z H Zhang
No abstract text is available yet for this article.
April 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/28366926/successful-treatment-of-rosai-dorfman-disease-using-in-situ-photoimmunotherapy
#13
Meng Li, Lei Shi, Min Luo, Jia Chen, Bo Wang, Fuhe Zhang, Uma Keyal, Anil Kumar Bhatta, Wei R Chen, Xiuli Wang
Rosai-Dorfman disease is difficult to cure. In situ photoimmunotherapy combines local photothermal therapy with immunoadjuvant. In the present case report, a 39-year-old Chinese man with Rosai-Dorfman disease lesions below the left nostril and left preauricular region was treated with in situ photoimmunotherapy. The patient was treated with daily application of topical imiquimod (5%) and laser irradiations every 2 weeks for 8 weeks. After three cycles of treatment, the lesions improved markedly without adverse effects...
March 31, 2017: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/28321353/paranasal-rosai-dorfman-disease-with-osseous-destruction
#14
Kevin Hur, Changxing Liu, Jeffrey A Koempel
Rosai-Dorfman disease is a rare histiocytic proliferative disorder of unknown etiology typically characterized by cervical lymphadenopathy. Extranodal involvement often manifests in the head and neck region. We present a 10-year-old male who presented to our hospital with left epiphora from an aggressive paranasal mass invading the left orbit with osseous destruction. The mass was surgically biopsied and debulked with histopathological examination revealing Rosai-Dorfman disease. Although rarely found in the sinuses, Rosai-Dorfman disease should be considered when evaluating sinonasal masses...
2017: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/28255989/an-unusual-case-of-multiple-cutaneous-rosai-dorfman-disease-involving-two-separate-parts-of-the-body
#15
Jinjing Jia, Qiong Tian, Haitao Zhang, Yan Zheng
No abstract text is available yet for this article.
March 3, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28235354/rosai-dorfman-disease-of-isolated-spinal-involvement-and-isolated-intracranial-involvement
#16
Kaichuang Yang, Manish Kolakshyapati, Tejashwi Shrestha, Lin Lou, Shuda Chen
No abstract text is available yet for this article.
February 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28230567/magnetic-resonance-imaging-features-of-solitary-hypothalamitis
#17
Hua Zhang, Jing Wang, Yue Wu, Ying Tang, Ran Tao, Hongying Ye, Zhenwei Yao
OBJECTIVE: The study aimed to characterize magnetic resonance imaging (MRI) findings of solitary hypothalamitis and evaluate their clinical value in diagnosis. METHODS: Magnetic resonance imaging scans, including T1-weighted imaging (T1WI), T2-weighted imaging (T2WI), and contrast-enhanced T1-weighted sequences, of 8 biopsy-proven hypothalamitis lesions were retrospectively analyzed along with MRI features including size, shape, signal intensity, enhancement pattern, correlation with adjacent tissues, and changes in infundibular stalk and sella turcica...
March 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28214412/histiocytoses-emerging-neoplasia-behind-inflammation
#18
REVIEW
Julien Haroche, Fleur Cohen-Aubart, Barret J Rollins, Jean Donadieu, Frédéric Charlotte, Ahmed Idbaih, Augusto Vaglio, Omar Abdel-Wahab, Jean-François Emile, Zahir Amoura
Histiocytoses are disorders characterised by inflammation and the accumulation of cells derived from the monocyte and macrophage lineages, which results in tissue damage. Although they are often considered rare disorders with protean clinical manifestations, considerable advances in the understanding of their genetics have led to increased clinical recognition of these conditions, and fuelled further insights into their pathogenesis. In this Review, we describe insights into the cells of origin, molecular pathology, clinical features, and treatment strategies for some of the most common histiocytic disorders, including Langerhans cell histiocytosis, Erdheim-Chester disease, and Rosai-Dorfman disease...
February 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28210574/rosai-dorfman-disease-affecting-the-maxilla
#19
Thaís Gimenez Miniello, Juliane Piragine Araujo, Norberto Nobuo Sugaya, Fernando Melhem Elias, Oslei Paes de Almeida, Fabio Abreu Alves
Rosai-Dorfman disease (RDD), formerly called sinus histiocytosis with massive lymphadenopathy, is a non-neoplastic proliferative histiocytic disorder with behavior ranging from highly aggressive to spontaneous remission. Although the lymph nodes are more commonly involved, any organ can be affected. This study aimed to describe the features and the follow-up of a case of extranodal RDD. Our patient was a 39-year-old woman who was referred with an 11-month history of pain in the right maxilla. On clinical examination, some upper right teeth presented full mobility with normal appearance of the surrounding gingiva...
October 2016: Autopsy & case reports
https://www.readbyqxmd.com/read/28173721/rosai-dorfman-disease-of-the-subdural-spine-with-a-long-segment-lesion-a-case-report-and-literature-review
#20
Ji Tu, Wen-Tian Li, Cao Yang
Rosai-Dorfman disease (RDD) or sinus histiocytosis with massive lymphadenopathy is a rare benign disorder usually characterized by massive painless cervical lymphadenopathy and systemic manifestations. Extranodal involvement, especially spinal involvement, is extremely rare. We report a 41-year-old man who presented with only intermittent dorsodynia. His condition was diagnosed as non-specific inflammatory disease on the basis of preoperative puncture biopsy results. We performed total surgical resection. Histopathological findings showed distinctive emperipolesis and immunohistochemistry results were positive for cluster of differentiation CD68 and S100 and negative for CD1a...
January 1, 2017: Journal of International Medical Research
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