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Rosai dorfman

B N Mahanta, T Goswami Mahanta
A young male presented with recurrent neck swellings with initial leucocyte count of 16800/mm3, with non-caseating glands on ultrasonography neck. FNAC showed mixed cellularity with histiocytic and marked lymphophagocytosis as seen in Rosai Dorfman Disease. Immunohistochemistry demonstrated CD 25, Ki 67 and CD 68 in histiocytes. Her responded to supportive treatment alone.
October 2016: Journal of the Association of Physicians of India
Matthew Raymond Summers, Gosta Pettersson, Joseph F Maalouf, Wael A Jaber
No abstract text is available yet for this article.
October 14, 2016: European Heart Journal
Harshit Jain, Nikhil Gupta, Jalees Fatima, Ritu Karoli, Vaibhav Shukla
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
Marta Drake-Pérez, James G Smirniotopoulos
This article reviews the most frequent extra-axial tumors of the central nervous system, from the most common meningioma to some uncommon conditions, like Rosai-Dorfman disease, focusing on imaging techniques, pearls, and pitfalls as well as a more practical approach.
November 2016: Neuroimaging Clinics of North America
Edward Chen, Peter Pavlidakey, Naveed Sami
No abstract text is available yet for this article.
September 2016: JAAD Case Reports
Jay Karajgikar, Gregory Grimaldi, Barak Friedman, John Hines
Rosai-Dorfman disease is a rare disorder of unknown etiology caused by the proliferation of histiocytes within lymph nodes, predominantly in the cervical chain. Extranodal sites may be involved as well, with involvement of nearly every organ system described in the literature. Abdominal and pelvic manifestations of Rosai-Dorfman disease are extremely rare. We present four cases of abdominal and pelvic involvement by Rosai-Dorfman disease, specifically within the biliary tract, pancreas, spleen, and presacral space...
September 13, 2016: Clinical Imaging
Zhengxiang Luo, Yansong Zhang, Penglai Zhao, Hucheng Lu, Kun Yang, Yuhai Zhang, Yanjun Zeng
OBJECTIVES: The study aimed to summarize the clinical characteristics of Rosai-Dorfman syndrome primarily involved in central nervous system and to explore diagnosis and treatment. METHODS: By combining literature review in with our study, we analyzed the clinical, imaging and pathological characteristics as well as treatment and prognosis for three cases of Rosai-Dorfman syndrome primarily involved in the central nervous system. RESULTS: The largest of multiple intracranial lesions was totally resected, and steroid administration and radiotherapy were performed in phases for the remaining lesions...
September 28, 2016: World Neurosurgery
Abid Hussain, Ashwani Tandon, Aruna K Prayaga, Tara Roshni Paul, Anukonda M V R Narendra
OBJECTIVES: Rosai-Dorfman disease (RDD) is an uncommon, benign histiocytic disorder of unknown etiology, typically presenting in young adulthood. We highlight the cytomorphology of RDD and correlate it with the histopathology. STUDY DESIGN: All cases diagnosed as RDD on fine-needle aspiration cytology between January 2001 and June 2015 were included. Clinical details were obtained from medical records. The cytology smears were reviewed along with the histopathology and immunohistochemistry, wherever available...
September 28, 2016: Acta Cytologica
Julie M Jorns
No abstract text is available yet for this article.
September 26, 2016: Breast Journal
Aziz El Majdoub, Aziza El Houari, Laila Chbani, Hinde El Fatemi, Abdelhak Khallouk, Moulay Hassan Farih
We report a rare case of an elderly woman presented with right renal mass with invasion of renal vein and several small lymphadenopathy in the hilar area. The diagnosis of kidney cancer is suspected and the patient underwent open radical nephrectomy, surrenalectomy and lymphadenectomy dissection. The pathologic examinations find a rosai dorfman disease. This unusual benign entity is uncommon in the kidney, but in medical imaging, it may simulate an infiltrative renal neoplasm, especially a lymphoma or leukemia or even renal cell carcinoma...
2016: Pan African Medical Journal
J J Colombo, E Linares Espinós, J López Tello, M M Lorido Cortes, J C Albillos Merino, L Martínez-Piñeiro
No abstract text is available yet for this article.
September 2016: Archivos Españoles de Urología
Neeta Malviya, Alexander Marzuka, Mokhtar Maamed-Tayeb, Lu Le, Travis Vandergriff
We report the case of a patient with a long-standing history of extranodal, sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) and no evidence of original cutaneous involvement as well as a history of herpes zoster of the left flank with post-herpetic neuralgia who went on to develop multiple, round-to-oval, red-brown, atrophic macules and thin papules at the sites of herpes zoster scars on the left flank. Histopathology showed a dense nodular infiltrate of lymphocytes with some plasma cells and numerous large pale-staining histiocytes (S100+/CD68+), consistent with Rosai-Dorfman disease...
September 9, 2016: Journal of Cutaneous Pathology
Arian Teymoorian, Truman M Earl, Brian B Borg
Rosai-Dorfman Disease (RDD) is rare and characterized by a proliferation of histiocytes with the potential to involve a variety of tissues and organ systems. However, the involvement of intra abdominal organs, particularly the biliary tree, is most uncommon. We present a case of RDD that caused obstructive cholagiopathy, manifested as a hepatic mass and yielded features consistent with cholangiocarcinoma at magnetic resonance imaging (MRI).
September 5, 2016: Clinical Gastroenterology and Hepatology
Daniel Vargas, J Caleb Richards, Daniel Ocazionez, Arlene Sirajuddin, Lorna Browne, Carlos S Restrepo
OBJECTIVE: The objectives of this article are: (1) to review common and rare manifestations of systemic and pulmonary Langerhans cell histiocytosis, Rosai-Dorfman disease, Erdheim-Chester disease and juvenile xanthogranuloma; (2) to provide the reader with important pathologic, epidemiologic and clinical features of these diseases. CONCLUSION: The histiocytoses are a diverse group of diseases which typically manifest with multiorgan involvement. Understanding the pathologic, epidemiologic, and clinical features of these entities can help the radiologist suggest an accurate diagnosis of histiocytosis when typical imaging features are encountered...
September 7, 2016: British Journal of Radiology
Qiao Zhou, Umer Ansari, Nandan Keshav, Fiona Davis, Maria Cundiff
A 71-year-old asymptomatic female with a history of breast cancer status after right total mastectomy had interval development of several new nodules in the left breast in a 1-year time span. Stereotactic biopsy was performed, which revealed multifocal Rosai Dorfman disease in the left breast. The patient was referred to hematology, and computed tomography of the chest/abdomen/pelvis did not demonstrate any lymphadenopathy elsewhere in the body. This case report discusses incidences of extranodal Rosai Dorfman disease and the differential for breast lesions that can present the same way...
September 2016: Radiology case reports
Bo Yuan Huang, Miao Zong, Wen Jing Zong, Yan Hui Sun, Hua Zhang, Hong Bo Zhang
Rosai-Dorfman disease (RDD) is a rare histioproliferative disorder that only occasionally involves the central nervous system. We present the diagnosis and treatment of five patients with intracranial RDD. The patients were preoperatively misdiagnosed as meningioma or eosinophilic granuloma. All five patients were treated by total or subtotal surgical resection and none of them experienced recurrence. Histopathological examination showed a characteristic emperipolesis, the lymphocytes were engulfed in the S-100 protein and CD68 positive histiocytes, with negative expression of CD1a...
October 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Y P Chen, X N Jiang, J P Lu, H Zhang, X Q Li, G Chen
OBJECTIVE: To investigate the clinicopathologic features, diagnosis and differential diagnosis of extranodal Rosai-Dorfman disease(RDD)of the breast. METHODS: Twelve cases of extranodal RDD of the breast were analyzed using hematoxylin-eosin stain and immunohistochemical staining.The morphological features and immunophenotype were observed by light microscopy, accompanied with a review of the literature. RESULTS: Twelve cases of extranodal RDD of the breast are presented...
August 8, 2016: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
Alexandra Kuzyk, Shane Silver, Sharon Wallace, Sate Hamza, John Toole
No abstract text is available yet for this article.
August 9, 2016: Journal of Cutaneous Medicine and Surgery
Pengcheng Zhu, Naping Li, Lu Yu, Mariajose Navia Miranda, Guoping Wang, Yaqi Duan
Histiocytosis is an uncommon disease characterized by excessive accumulation of histiocytes. Here, we report a rare case of non-Langerhans-cell histiocytosis in a 51-year-old woman who presented with severe symptoms of pericardial effusion. Radiologic investigation also detected multiple bone (lower limbs, vertebrae, ribs, and ilium) lesions. Resected pericardium showed abundant mono- or multi-nucleated non-foamy histiocytes (CD68+/CD163+/S-100+/CD1α-/Langerin-) in a fibroinflammatory background. The histiocytes demonstrated emperipolesis of lymphocytes, a hallmark feature of Rosai-Dorfman Disease (RDD)...
July 28, 2016: Cancer Research and Treatment: Official Journal of Korean Cancer Association
Zdeněk Adam, Jiří Mašlaň, Leoš Křen, Roman Kodet, Renata Koukalová, Zdeněk Řehák, Libor Červinek, Luděk Pour, Marta Krejčí, Viera Sandecká, Zdeněk Král, Jiří Mayer
UNLABELLED: Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) is a very rare disease belonging to a group of histiocytoses (more precisely non-Langerhans cell histiocytoses). Rosai-Dorfman disease is characterised by the presence of atypical histiocytic cells in the sinuses of lymph nodes or in the extranodal lymphoid tissue, absorbing lymphocytes and plasma cells. The structure and function of the absorbed cells is not impaired and they can leave histiocytes as viable cells...
2016: Vnitr̆ní Lékar̆ství
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